Motif ID: IRF1,2,7.p3

Z-value: 5.243


Transcription factors associated with IRF1,2,7.p3:

Gene SymbolEntrez IDGene Name
IRF1 3659 interferon regulatory factor 1
IRF2 3660 interferon regulatory factor 2
IRF7 3665 interferon regulatory factor 7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
IRF7chr11_-_615998,
chr11_-_615649
0.926.3e-07Click!
IRF1chr5_-_1318264260.835.9e-05Click!
IRF2chr4_-_1853956160.774.9e-04Click!


Activity profile for motif IRF1,2,7.p3.

activity profile for motif IRF1,2,7.p3


Sorted Z-values histogram for motif IRF1,2,7.p3

Sorted Z-values for motif IRF1,2,7.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of IRF1,2,7.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_79086087 28.820 NM_006820
IFI44L
interferon-induced protein 44-like
chr10_+_91152321 19.980 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr21_+_42792441 18.988 NM_001144925
MX1
myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr1_+_948846 18.825 NM_005101
ISG15
ISG15 ubiquitin-like modifier
chr1_-_27998719 18.824 NM_002038
NM_022872
NM_022873
IFI6


interferon, alpha-inducible protein 6


chr1_-_27998658 17.795 IFI6
interferon, alpha-inducible protein 6
chr1_-_27998700 17.751 IFI6
interferon, alpha-inducible protein 6
chr11_-_615920 17.647 IRF7
interferon regulatory factor 7
chr11_-_615998 17.338 NM_001572
NM_004029
IRF7

interferon regulatory factor 7

chr21_+_42733916 15.532 NM_002463
LOC100131190
MX2
uncharacterized LOC100131190
myxovirus (influenza virus) resistance 2 (mouse)
chr12_+_25205488 12.829 LRMP
lymphoid-restricted membrane protein
chr4_+_89378234 12.665 NM_016323
HERC5
hect domain and RLD 5
chr1_+_158979681 12.575 NM_001206567
NM_005531
IFI16

interferon, gamma-inducible protein 16

chr12_+_113416267 12.444 NM_001032731
NM_002535
NM_016817
OAS2


2'-5'-oligoadenylate synthetase 2, 69/71kDa


chr6_+_32821924 12.244 NM_002800
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
chr4_-_169239816 12.136 NM_017631
DDX60
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr1_+_79115476 11.330 NM_006417
IFI44
interferon-induced protein 44
chr2_-_89165652 11.028


chr11_+_5710816 11.013 NM_001199573
NM_006074
TRIM22

tripartite motif containing 22

chr1_+_174843523 10.798 NM_001243763
RABGAP1L
RAB GTPase activating protein 1-like
chr11_-_615649 10.284 NM_004031
IRF7
interferon regulatory factor 7
chr5_-_149792276 10.252 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr22_+_18632841 10.092 USP18
ubiquitin specific peptidase 18
chr6_-_32812189 9.966 PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr22_+_18632704 9.826 NM_017414
USP18
ubiquitin specific peptidase 18
chr6_-_32811773 9.329 NM_148919
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr10_+_91087601 8.906 NM_001549
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr5_-_149792370 8.657 NM_001025158
NM_001025159
NM_004355
CD74


CD74 molecule, major histocompatibility complex, class II invariant chain


chr11_-_57335080 8.615 NM_004223
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chr10_+_91092238 8.493 NM_001031683
IFIT3
interferon-induced protein with tetratricopeptide repeats 3
chr6_-_32821743 8.488 NM_000593
TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_-_32821592 8.237 TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr17_-_40264687 8.099 NM_024119
DHX58
DEXH (Asp-Glu-X-His) box polypeptide 58
chr1_-_25291474 8.087 NM_001031680
RUNX3
runt-related transcription factor 3
chr6_+_6588933 8.029 NM_004271
LY86
lymphocyte antigen 86
chr7_+_74188308 7.966 NM_000265
NCF1
NCF1B
neutrophil cytosolic factor 1
neutrophil cytosolic factor 1B pseudogene
chr1_-_9129620 7.901 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr12_+_25205180 7.773 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chr2_-_191878908 7.399 STAT1
signal transducer and activator of transcription 1, 91kDa
chr2_-_231084600 7.311 NM_004509
NM_004510
NM_080424
SP110


SP110 nuclear body protein


chr2_-_191878883 7.197 STAT1
signal transducer and activator of transcription 1, 91kDa
chr21_+_42797977 7.187 NM_002462
NM_001178046
MX1

myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)

chr16_-_67970651 6.906 PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr12_+_113376001 6.883 OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr15_+_89182038 6.800 NM_002201
ISG20
interferon stimulated exonuclease gene 20kDa
chr2_-_191878924 6.736 NM_007315
NM_139266
STAT1

signal transducer and activator of transcription 1, 91kDa

chr17_+_25958257 6.733 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_25958245 6.700 LGALS9
lectin, galactoside-binding, soluble, 9
chr12_+_113376301 6.650 OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr19_-_7766978 6.646 NM_001220500
NM_002002
FCER2

Fc fragment of IgE, low affinity II, receptor for (CD23)

chr11_-_104972147 6.598 NM_001007232
NM_001223
NM_033292
NM_033293
NM_033294
NM_033295
CARD17
CASP1




caspase recruitment domain family, member 17
caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)




chr6_-_32821412 6.552 TAP1
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_-_29527701 6.473 NM_006398
UBD
ubiquitin D
chr4_+_142557722 6.391 NM_000585
NM_172175
IL15

interleukin 15

chr16_-_67970734 6.347 NM_002801
PSMB10
proteasome (prosome, macropain) subunit, beta type, 10
chr1_+_158801105 6.287 NM_002432
MNDA
myeloid cell nuclear differentiation antigen
chr17_+_6659155 6.285 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chr2_-_89442551 6.282 IGKC
IGK@
immunoglobulin kappa constant
immunoglobulin kappa locus
chr17_+_25958217 6.199 LGALS9
lectin, galactoside-binding, soluble, 9
chr2_-_191878882 6.142 STAT1
signal transducer and activator of transcription 1, 91kDa
chr12_+_113376226 6.096 NM_006187
OAS3
2'-5'-oligoadenylate synthetase 3, 100kDa
chr6_-_29527477 6.082 UBD
ubiquitin D
chr17_+_25958192 6.067 LGALS9
lectin, galactoside-binding, soluble, 9
chr17_+_25958151 6.048 NM_002308
NM_009587
LGALS9

lectin, galactoside-binding, soluble, 9

chr6_-_31239489 6.028 HLA-B
HLA-C
major histocompatibility complex, class I, B
major histocompatibility complex, class I, C
chr14_-_93214873 5.998 NM_001008530
NM_005606
LGMN

legumain

chr1_-_89530890 5.901 NM_002053
GBP1
guanylate binding protein 1, interferon-inducible
chr4_-_40517913 5.756 NM_019027
RBM47
RNA binding motif protein 47
chr1_-_9129583 5.750 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr13_+_50070096 5.743 PHF11
PHD finger protein 11
chr10_+_97515408 5.739 NM_001164178
NM_001164181
NM_001164179
NM_001164182
NM_001164183
NM_001776
ENTPD1





ectonucleoside triphosphate diphosphohydrolase 1





chr2_+_33701320 5.660 NM_001139488
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr5_+_49962920 5.658 PARP8
poly (ADP-ribose) polymerase family, member 8
chr17_+_6659356 5.641 XAF1
XIAP associated factor 1
chr12_+_113344811 5.545 OAS1
2'-5'-oligoadenylate synthetase 1, 40/46kDa
chr2_+_231280906 5.528 SP100
SP100 nuclear antigen
chr11_-_60719116 5.505 NM_016582
SLC15A3
solute carrier family 15, member 3
chr1_+_64058891 5.499 NM_002633
PGM1
phosphoglucomutase 1
chr6_-_133084585 5.495 NM_078488
VNN2
vanin 2
chr7_-_150329285 5.429 GIMAP6
GTPase, IMAP family member 6
chr13_+_50070527 5.405 NM_001040444
PHF11
PHD finger protein 11
chr6_+_32605182 5.358 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr4_-_76944585 5.349 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr3_+_187086167 5.347 NM_022147
RTP4
receptor (chemosensory) transporter protein 4
chr10_+_97471535 5.158 NM_001098175
ENTPD1
ectonucleoside triphosphate diphosphohydrolase 1
chr3_+_113251217 5.127 NM_017699
SIDT1
SID1 transmembrane family, member 1
chr6_+_26440699 5.107 NM_001242803
NM_006994
NM_197974
BTN3A3


butyrophilin, subfamily 3, member A3


chr11_+_5646206 5.068 NM_021616
TRIM34
tripartite motif containing 34
chr4_+_89300110 5.046 HERC6
hect domain and RLD 6
chr10_+_63808968 4.970 NM_001244638
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr17_+_18380097 4.907 NM_001040078
LGALS9B
LGALS9C
lectin, galactoside-binding, soluble, 9B
lectin, galactoside-binding, soluble, 9C
chr2_-_152146133 4.899 NMI
N-myc (and STAT) interactor
chr13_+_50069745 4.846 NM_001040443
PHF11
PHD finger protein 11
chr1_-_9129666 4.804 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chr2_+_33701678 4.790 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr6_+_31540092 4.721 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr5_-_95158465 4.696 NM_001118890
NM_001243658
NM_001243659
NM_002064
GLRX



glutaredoxin (thioltransferase)



chr5_-_95158365 4.525 GLRX
glutaredoxin (thioltransferase)
chr19_+_18284578 4.519 NM_006332
IFI30
interferon, gamma-inducible protein 30
chr1_-_170038055 4.502 NM_001204517
KIFAP3
kinesin-associated protein 3
chr2_-_152146373 4.491 NM_004688
NMI
N-myc (and STAT) interactor
chr19_+_10196757 4.475 NM_018381
C19orf66
chromosome 19 open reading frame 66
chr20_+_44746948 4.406 CD40
CD40 molecule, TNF receptor superfamily member 5
chr17_+_72462766 4.341 CD300A
CD300a molecule
chr8_+_54764367 4.299 NM_170587
RGS20
regulator of G-protein signaling 20
chr19_+_10196972 4.219 C19orf66
chromosome 19 open reading frame 66
chr17_-_20370819 4.219 NM_001042685
LGALS9B
lectin, galactoside-binding, soluble, 9B
chr13_+_31309644 4.199 NM_001629
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr19_+_18284619 4.197 IFI30
interferon, gamma-inducible protein 30
chr10_+_91061705 4.154 NM_001547
IFIT2
interferon-induced protein with tetratricopeptide repeats 2
chr2_-_163174816 4.139 NM_022168
IFIH1
interferon induced with helicase C domain 1
chr12_+_94542239 4.092 NM_005761
PLXNC1
plexin C1
chr3_+_48507621 4.016 TREX1
three prime repair exonuclease 1
chr10_+_11047274 3.994 CELF2
CUGBP, Elav-like family member 2
chrX_+_37639246 3.988 NM_000397
CYBB
cytochrome b-245, beta polypeptide
chr15_+_45003659 3.930 NM_004048
B2M
beta-2-microglobulin
chr19_+_18284631 3.889 IFI30
interferon, gamma-inducible protein 30
chr9_-_32526164 3.805 NM_014314
DDX58
DEAD (Asp-Glu-Ala-Asp) box polypeptide 58
chr7_+_134832765 3.759 NM_018295
TMEM140
transmembrane protein 140
chr6_-_31324955 3.712 HLA-B
major histocompatibility complex, class I, B
chr22_+_39473009 3.605 NM_021822
APOBEC3G
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3G
chr3_+_48507209 3.603 NM_016381
NM_033629
TREX1

three prime repair exonuclease 1

chr13_+_31309690 3.576 ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr6_+_29794743 3.571 NM_002127
HLA-G
major histocompatibility complex, class I, G
chr2_+_68592317 3.470 NM_002664
PLEK
pleckstrin
chr11_-_104839263 3.453 NM_001225
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr14_-_23284565 3.434 SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chrX_+_37639306 3.424 CYBB
cytochrome b-245, beta polypeptide
chr13_-_46756295 3.393 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_+_7055753 3.377 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr7_-_150329735 3.346 NM_001244071
NM_001244072
NM_024711
GIMAP6


GTPase, IMAP family member 6


chr4_-_156874993 3.340 NM_001334
CTSO
cathepsin O
chrX_+_80457559 3.334 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr3_-_49851356 3.320 NM_003335
UBA7
ubiquitin-like modifier activating enzyme 7
chr16_+_29831714 3.212 NM_005115
NM_017458
MVP

major vault protein

chr19_+_10197023 3.189 C19orf66
chromosome 19 open reading frame 66
chr17_+_72462780 3.134 CD300A
CD300a molecule
chr2_+_231280870 3.075 NM_001080391
NM_001206701
NM_001206702
NM_001206703
NM_003113
SP100




SP100 nuclear antigen




chr1_+_174844655 3.071 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr4_+_37892698 3.063 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr3_+_122044010 3.052 NM_005213
CSTA
cystatin A (stefin A)
chr10_+_115439632 3.045 CASP7
caspase 7, apoptosis-related cysteine peptidase
chr2_+_68592432 3.023 PLEK
pleckstrin
chr11_-_57335756 2.968 NM_198183
UBE2L6
ubiquitin-conjugating enzyme E2L 6
chrX_+_80457302 2.965 NM_003022
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr1_-_154580481 2.947 ADAR
adenosine deaminase, RNA-specific
chr12_-_10022457 2.923 NM_005127
CLEC2B
C-type lectin domain family 2, member B
chr10_+_115439425 2.923 NM_001227
NM_033338
NM_033339
CASP7


caspase 7, apoptosis-related cysteine peptidase


chr12_+_6561176 2.921 NM_018009
TAPBPL
TAP binding protein-like
chr12_-_10021932 2.869 CLEC2B
C-type lectin domain family 2, member B
chr2_+_69969105 2.846 NM_001153
ANXA4
annexin A4
chr5_+_156696351 2.816 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr16_+_29831755 2.810 MVP
major vault protein
chr19_+_6887576 2.808 NM_001974
EMR1
egf-like module containing, mucin-like, hormone receptor-like 1
chr1_-_154580632 2.774 ADAR
adenosine deaminase, RNA-specific
chr3_-_49851217 2.761 UBA7
ubiquitin-like modifier activating enzyme 7
chr7_+_128580725 2.728 NM_001098627
IRF5
interferon regulatory factor 5
chr13_-_46756326 2.720 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr10_+_91174303 2.692 NM_012420
IFIT5
interferon-induced protein with tetratricopeptide repeats 5
chrX_+_80457597 2.684 SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr18_+_48405486 2.656 ME2
malic enzyme 2, NAD(+)-dependent, mitochondrial
chr2_+_231090443 2.655 NM_001005176
NM_007237
SP140

SP140 nuclear body protein

chr7_-_92747317 2.642 NM_001193307
NM_017654
SAMD9

sterile alpha motif domain containing 9

chr10_+_70847857 2.621 SRGN
serglycin
chr6_-_30181113 2.611 TRIM26
tripartite motif containing 26
chr1_-_154580677 2.587 NM_001111
NM_015840
NM_015841
ADAR


adenosine deaminase, RNA-specific


chr8_-_95274520 2.567 GEM
GTP binding protein overexpressed in skeletal muscle
chr17_-_33759518 2.566 NM_018042
SLFN12
schlafen family member 12
chr6_-_30181197 2.563 NM_001242783
NM_003449
TRIM26

tripartite motif containing 26

chr20_-_43280359 2.523 NM_000022
ADA
adenosine deaminase
chr6_+_87969619 2.483 ZNF292
zinc finger protein 292
chr13_-_46756291 2.477 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr12_+_8276227 2.450 NM_016184
NM_194447
NM_194448
NM_194450
CLEC4A



C-type lectin domain family 4, member A



chr7_-_92747269 2.449 SAMD9
sterile alpha motif domain containing 9
chr16_-_21289637 2.440 CRYM
crystallin, mu
chr11_+_32112607 2.410 RCN1
reticulocalbin 1, EF-hand calcium binding domain
chr8_+_96145942 2.407 NM_024613
PLEKHF2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr18_+_48405426 2.403 NM_001168335
NM_002396
ME2

malic enzyme 2, NAD(+)-dependent, mitochondrial

chr19_+_50432399 2.386 NM_001193646
ATF5
activating transcription factor 5
chr6_+_26365397 2.362 NM_001197247
NM_001197249
NM_007047
NM_001197248
BTN3A2



butyrophilin, subfamily 3, member A2



chr17_+_72462521 2.360 NM_007261
CD300A
CD300a molecule
chr2_+_231280933 2.354 SP100
SP100 nuclear antigen
chr10_+_70847817 2.312 NM_002727
SRGN
serglycin
chr8_+_18079176 2.293 NM_001160174
NAT1
N-acetyltransferase 1 (arylamine N-acetyltransferase)
chr11_+_22696318 2.252 NM_005256
GAS2
growth arrest-specific 2
chr11_+_1874199 2.250 NM_002339
LSP1
lymphocyte-specific protein 1
chr13_-_30424795 2.232 NM_007106
UBL3
ubiquitin-like 3
chr13_-_30423599 2.213 UBL3
ubiquitin-like 3
chr2_-_231090443 2.208 NM_001185015
SP110
SP110 nuclear body protein
chr14_-_106691698 2.208


chr8_-_95274540 2.202 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr14_+_94577078 2.198 NM_001130080
NM_005532
IFI27

interferon, alpha-inducible protein 27

chr2_-_37384026 2.192 EIF2AK2
eukaryotic translation initiation factor 2-alpha kinase 2
chr9_+_33265043 2.179 CHMP5
charged multivesicular body protein 5
chr9_+_33264876 2.156 NM_001195536
NM_016410
CHMP5

charged multivesicular body protein 5

chr2_+_85811530 2.155 NM_006634
VAMP5
vesicle-associated membrane protein 5 (myobrevin)
chr11_-_4414887 2.131 NM_003141
TRIM21
tripartite motif containing 21
chr16_-_11350038 2.117 NM_003745
SOCS1
suppressor of cytokine signaling 1
chr2_-_37384147 2.099 NM_001135651
NM_002759
EIF2AK2

eukaryotic translation initiation factor 2-alpha kinase 2

chr19_+_44669214 2.092 NM_001146220
NM_001032373
NM_001032374
NM_015919
NM_001032372
ZNF226




zinc finger protein 226





Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
6.46 8.03e-33 GO:0006955 immune response
4.62 8.24e-29 GO:0002376 immune system process
24.73 5.73e-25 GO:0060337 type I interferon-mediated signaling pathway
24.73 5.73e-25 GO:0071357 cellular response to type I interferon
24.34 9.13e-25 GO:0034340 response to type I interferon
5.52 1.60e-24 GO:0006952 defense response
8.50 1.66e-24 GO:0045087 innate immune response
11.62 2.24e-22 GO:0019221 cytokine-mediated signaling pathway
10.49 6.35e-21 GO:0071345 cellular response to cytokine stimulus
8.26 1.61e-19 GO:0034097 response to cytokine stimulus
13.28 3.77e-11 GO:0034341 response to interferon-gamma
9.13 4.26e-11 GO:0009615 response to virus
14.67 3.58e-10 GO:0060333 interferon-gamma-mediated signaling pathway
13.35 1.43e-09 GO:0071346 cellular response to interferon-gamma
2.28 3.34e-09 GO:0006950 response to stress
3.90 1.29e-08 GO:0071310 cellular response to organic substance
4.58 9.99e-07 GO:0051707 response to other organism
23.54 8.21e-06 GO:0048002 antigen processing and presentation of peptide antigen
1.53 1.71e-05 GO:0050896 response to stimulus
29.49 1.98e-05 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I
3.76 4.19e-05 GO:0009607 response to biotic stimulus
2.77 4.75e-05 GO:0070887 cellular response to chemical stimulus
11.06 8.89e-05 GO:0019882 antigen processing and presentation
3.05 1.20e-04 GO:0002682 regulation of immune system process
3.63 1.60e-04 GO:0050776 regulation of immune response
11.62 3.15e-04 GO:0032479 regulation of type I interferon production
2.71 3.31e-04 GO:0051704 multi-organism process
2.07 6.80e-04 GO:0007166 cell surface receptor linked signaling pathway
1.70 9.87e-04 GO:0007165 signal transduction
36.51 1.83e-03 GO:0019883 antigen processing and presentation of endogenous antigen
3.34 2.16e-03 GO:0002684 positive regulation of immune system process
3.80 2.30e-03 GO:0031347 regulation of defense response
2.23 2.59e-03 GO:0010033 response to organic substance
14.20 2.84e-03 GO:0032480 negative regulation of type I interferon production
1.99 2.91e-03 GO:0048583 regulation of response to stimulus
2.60 4.44e-03 GO:0048584 positive regulation of response to stimulus
11.28 1.18e-02 GO:0030888 regulation of B cell proliferation
4.57 1.19e-02 GO:0050867 positive regulation of cell activation
3.72 1.20e-02 GO:0050778 positive regulation of immune response
3.35 1.26e-02 GO:0044419 interspecies interaction between organisms
3.88 1.48e-02 GO:0010740 positive regulation of intracellular protein kinase cascade
6.91 1.80e-02 GO:0043900 regulation of multi-organism process
5.28 1.81e-02 GO:0043122 regulation of I-kappaB kinase/NF-kappaB cascade
2.27 1.82e-02 GO:0042981 regulation of apoptosis
2.25 2.08e-02 GO:0043067 regulation of programmed cell death
1.56 2.11e-02 GO:0023052 signaling
3.73 2.26e-02 GO:0001817 regulation of cytokine production
2.22 2.71e-02 GO:0010941 regulation of cell death
4.57 2.75e-02 GO:0051251 positive regulation of lymphocyte activation
12.78 3.41e-02 GO:0030890 positive regulation of B cell proliferation
38.33 3.44e-02 GO:0002478 antigen processing and presentation of exogenous peptide antigen
38.33 3.44e-02 GO:0002483 antigen processing and presentation of endogenous peptide antigen
38.33 3.44e-02 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I
3.76 4.07e-02 GO:0050865 regulation of cell activation
3.18 4.25e-02 GO:0010627 regulation of intracellular protein kinase cascade
1.31 4.70e-02 GO:0050789 regulation of biological process
3.98 4.71e-02 GO:0051249 regulation of lymphocyte activation

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
4.50 2.28e-02 GO:0009897 external side of plasma membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
12.78 2.70e-05 GO:0003823 antigen binding
19.66 6.50e-03 GO:0050664 oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor
27.38 2.21e-02 GO:0015197 peptide transporter activity
23.96 3.49e-02 GO:0016175 superoxide-generating NADPH oxidase activity