Motif ID: ESRRA.p2

Z-value: 1.546


Transcription factors associated with ESRRA.p2:

Gene SymbolEntrez IDGene Name
ESRRA 2101 estrogen-related receptor alpha



Activity profile for motif ESRRA.p2.

activity profile for motif ESRRA.p2


Sorted Z-values histogram for motif ESRRA.p2

Sorted Z-values for motif ESRRA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESRRA.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_17923110 2.347 NM_002248
KCNN1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 1
chr9_+_17568952 2.338 NM_003026
SH3GL2
SH3-domain GRB2-like 2
chr5_-_148014282 2.273 HTR4
5-hydroxytryptamine (serotonin) receptor 4
chr5_+_149549712 2.073 NM_014228
SLC6A7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr17_-_70367479 2.053 NM_000835
GRIN2C
glutamate receptor, ionotropic, N-methyl D-aspartate 2C
chr22_-_29290875 2.030 NM_004861
GAL3ST1
galactose-3-O-sulfotransferase 1
chr19_+_540849 2.012 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr15_+_41672543 2.001 NM_020990
CKMT1B
CKMT1A
creatine kinase, mitochondrial 1B
creatine kinase, mitochondrial 1A
chr5_-_1647617 1.970 SDHAP3
succinate dehydrogenase complex, subunit A, flavoprotein pseudogene 3
chr22_-_28041474 1.952 RASL10A
RAS-like, family 10, member A
chr11_+_65815940 1.928 NM_153266
TMEM151A
transmembrane protein 151A
chr22_-_28041650 1.847 NM_001007279
NM_006477
RASL10A

RAS-like, family 10, member A

chr11_+_65815911 1.843 TMEM151A
transmembrane protein 151A
chr19_-_4486202 1.668 NM_001013706
PLIN5
perilipin 5
chr14_-_47213906 1.654 NM_001113498
MDGA2
MAM domain containing glycosylphosphatidylinositol anchor 2
chr10_+_44726635 1.621 NM_001123376
TMEM72
transmembrane protein 72
chrX_-_1470862 1.609 NM_001636
SLC25A6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 6
chr9_-_21340885 1.596 NM_021002
IFNA6
interferon, alpha 6
chr14_-_20572783 1.542 NM_001012264
RNASE13
ribonuclease, RNase A family, 13 (non-active)
chr5_-_63293301 1.492 NM_000524
HTR1A
5-hydroxytryptamine (serotonin) receptor 1A
chr11_-_64268841 1.450 NM_001098670
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr11_-_64268126 1.430 NM_001098671
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr20_+_36867708 1.429 NM_001172735
NM_015568
PPP1R16B

protein phosphatase 1, regulatory (inhibitor) subunit 16B

chr17_-_70430839 1.376 NM_173477
USH1G
Usher syndrome 1G (autosomal recessive)
chr22_-_42589543 1.361 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr4_-_21308415 1.318 NM_001035003
KCNIP4
Kv channel interacting protein 4
chr12_+_20413445 1.313 NM_000921
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr14_-_103058865 1.303 NM_001823
CKB
creatine kinase, brain
chr3_-_27738788 1.301 NM_005442
EOMES
eomesodermin
chr3_+_142253432 1.292 NM_080862
SPSB4
splA/ryanodine receptor domain and SOCS box containing 4
chr22_+_23221114 1.235 NM_016327
UPB1
ureidopropionase, beta
chr12_-_116021473 1.231 NM_001168325
NM_017899
TESC

tescalcin

chr17_+_7549138 1.191 NM_001406
EFNB3
ephrin-B3
chr1_+_29086206 1.180 EPB41
erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)
chr12_+_56299959 1.174 NM_133489
SLC26A10
solute carrier family 26, member 10
chr10_+_105334704 1.170 NEURL
neuralized homolog (Drosophila)
chr14_+_69021149 1.163 NM_001161498
UPF0639
UPF0639 protein
chr15_+_41772375 1.152 NM_001015001
CKMT1A
creatine kinase, mitochondrial 1A
chr11_-_132318741 1.144 OPCML
opioid binding protein/cell adhesion molecule-like
chr19_-_60360768 1.112 NM_000363
TNNI3
troponin I type 3 (cardiac)
chr3_+_134947788 1.110 TF
transferrin
chr22_+_29848923 1.106 NM_001002837
INPP5J
inositol polyphosphate-5-phosphatase J
chr5_-_148013908 1.090 NM_000870
HTR4
5-hydroxytryptamine (serotonin) receptor 4
chr11_-_132318080 1.090 NM_002545
OPCML
opioid binding protein/cell adhesion molecule-like
chr19_-_44518516 1.075 NM_004877
GMFG
glia maturation factor, gamma
chr17_+_71586857 1.074 NM_180990
ZACN
zinc activated ligand-gated ion channel
chr5_-_35266305 1.067 PRLR
prolactin receptor
chr3_-_180805104 1.036 NM_020409
NM_177988
MRPL47

mitochondrial ribosomal protein L47

chr12_-_642786 0.999 NM_016533
NINJ2
ninjurin 2
chr20_-_61600834 0.982 NM_001958
EEF1A2
eukaryotic translation elongation factor 1 alpha 2
chr3_+_134947940 0.972 TF
transferrin
chr12_-_52980914 0.971 NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr12_-_52980984 0.971 NM_001136023
NFE2
nuclear factor (erythroid-derived 2), 45kDa
chr3_+_134947894 0.949 TF
transferrin
chr1_-_152431175 0.938 NM_152263
TPM3
tropomyosin 3
chr11_-_84311867 0.923 DLG2
discs, large homolog 2 (Drosophila)
chr3_-_10724715 0.921 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr18_-_55136673 0.917 NM_181654
CPLX4
complexin 4
chr5_+_149550003 0.914 SLC6A7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr5_-_35266550 0.895 NM_000949
PRLR
prolactin receptor
chr7_-_100630912 0.883 NM_178176
MOGAT3
monoacylglycerol O-acyltransferase 3
chr1_+_29086156 0.873 NM_001166005
NM_001166007
NM_004437
NM_203342
NM_203343
EPB41




erythrocyte membrane protein band 4.1 (elliptocytosis 1, RH-linked)




chr17_-_34014390 0.872 SRCIN1
SRC kinase signaling inhibitor 1
chrX_-_132377087 0.871 GPC4
glypican 4
chrX_+_48505097 0.865 NM_001080489
GLOD5
glyoxalase domain containing 5
chr11_+_268569 0.859 NM_138329
NLRP6
NLR family, pyrin domain containing 6
chr18_-_5533967 0.856 NM_012307
EPB41L3
erythrocyte membrane protein band 4.1-like 3
chr10_-_103525646 0.853 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr20_-_43767069 0.836 NM_172006
NM_172131
WFDC10B

WAP four-disulfide core domain 10B

chr4_-_44145266 0.831 KCTD8
potassium channel tetramerisation domain containing 8
chr15_-_76210611 0.819 NM_006383
CIB2
calcium and integrin binding family member 2
chr8_+_120289735 0.812 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr3_+_134947573 0.810 NM_001063
TF
transferrin
chr12_-_107257205 0.810 NM_001142343
NM_001142344
NM_004072
CMKLR1


chemokine-like receptor 1


chr22_+_35586950 0.808 NM_000631
NM_013416
NCF4

neutrophil cytosolic factor 4, 40kDa

chr8_-_61356436 0.806 NM_004056
CA8
carbonic anhydrase VIII
chr12_+_76749199 0.793 NM_014903
NAV3
neuron navigator 3
chr11_-_45264193 0.789 NM_020826
SYT13
synaptotagmin XIII
chr2_+_219453487 0.782 NM_025216
WNT10A
wingless-type MMTV integration site family, member 10A
chr5_+_176717553 0.781


chr3_-_152449591 0.779 NM_001081455
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chr20_-_24987615 0.775 NM_032501
ACSS1
acyl-CoA synthetase short-chain family member 1
chr3_+_9720509 0.766 NM_153635
CPNE9
copine family member IX
chr20_-_44713466 0.764 NM_001193339
NM_001193342
NM_022829
SLC13A3


solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3


chr7_+_45580704 0.759 ADCY1
adenylate cyclase 1 (brain)
chr20_+_41621119 0.751 SGK2
serum/glucocorticoid regulated kinase 2
chr1_+_157824239 0.750 NM_001639
APCS
amyloid P component, serum
chr19_+_50693570 0.748 NM_001080401
PPM1N
protein phosphatase, Mg2+/Mn2+ dependent, 1N (putative)
chr18_+_42751510 0.745 KATNAL2
katanin p60 subunit A-like 2
chr15_+_76644882 0.725 NM_000745
CHRNA5
cholinergic receptor, nicotinic, alpha 5
chr8_+_36760999 0.716 NM_001031836
KCNU1
potassium channel, subfamily U, member 1
chr1_+_234916376 0.716 NM_001103
ACTN2
actinin, alpha 2
chr2_+_74594093 0.705 TLX2
T-cell leukemia homeobox 2
chr4_+_44375165 0.704 NM_021927
GUF1
GUF1 GTPase homolog (S. cerevisiae)
chr2_-_31293882 0.678 NM_001145122
CAPN14
calpain 14
chr14_+_87560646 0.676 LOC283587
hypothetical protein LOC283587
chrX_+_147389825 0.675 NM_001169122
NM_001169123
NM_001169124
NM_001169125
NM_002025
AFF2




AF4/FMR2 family, member 2




chr5_+_176807931 0.672 NM_001174102
PRR7
proline rich 7 (synaptic)
chr10_+_68355797 0.671 NM_178011
LRRTM3
leucine rich repeat transmembrane neuronal 3
chr20_+_41621079 0.668 NM_170693
SGK2
serum/glucocorticoid regulated kinase 2
chr8_+_100025806 0.659 NM_001142462
NM_053001
OSR2

odd-skipped related 2 (Drosophila)

chr12_-_16652202 0.655 NM_001001395
LMO3
LIM domain only 3 (rhombotin-like 2)
chr14_+_99220349 0.655 NM_006668
CYP46A1
cytochrome P450, family 46, subfamily A, polypeptide 1
chr13_+_32488477 0.654 NM_004795
KL
klotho
chr14_+_41146513 0.651 NM_152447
LRFN5
leucine rich repeat and fibronectin type III domain containing 5
chr19_-_44518465 0.645 GMFG
glia maturation factor, gamma
chr14_-_74400288 0.630 NM_001080408
PROX2
prospero homeobox 2
chr14_+_36200867 0.630 PAX9
paired box 9
chr19_+_19183763 0.628 NM_004386
NCAN
neurocan
chr11_-_64582568 0.623 NM_005468
NAALADL1
N-acetylated alpha-linked acidic dipeptidase-like 1
chr13_-_51483473 0.620 NM_000053
NM_001005918
ATP7B

ATPase, Cu++ transporting, beta polypeptide

chr10_-_97190885 0.619 NM_001034954
NM_001034955
NM_001034956
NM_001034957
NM_006434
SORBS1




sorbin and SH3 domain containing 1




chr14_-_69616616 0.599 NM_182936
NM_001130417
SLC8A3

solute carrier family 8 (sodium/calcium exchanger), member 3

chr14_+_36200815 0.584 PAX9
paired box 9
chr7_+_45580606 0.580 NM_021116
ADCY1
adenylate cyclase 1 (brain)
chr8_-_100975417 0.575 NM_004374
COX6C
cytochrome c oxidase subunit VIc
chr1_+_32489426 0.570 NM_005356
LCK
lymphocyte-specific protein tyrosine kinase
chr2_-_154043403 0.568 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr8_-_100975086 0.550 COX6C
cytochrome c oxidase subunit VIc
chr17_+_37247568 0.549 NM_152467
KLHL10
kelch-like 10 (Drosophila)
chr14_-_73296643 0.545 NM_194278
C14orf43
chromosome 14 open reading frame 43
chr14_-_103058568 0.541 CKB
creatine kinase, brain
chr12_-_3732478 0.541 EFCAB4B
EF-hand calcium binding domain 4B
chr3_-_134863316 0.537 NM_007027
TOPBP1
topoisomerase (DNA) II binding protein 1
chr1_-_172153024 0.537 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr2_+_104838177 0.536 NM_006236
POU3F3
POU class 3 homeobox 3
chr3_+_51716120 0.536 NM_000839
NM_001130063
GRM2

glutamate receptor, metabotropic 2

chr22_-_29197944 0.533 NM_174975
SEC14L3
SEC14-like 3 (S. cerevisiae)
chr19_+_55614006 0.531 NM_003121
SPIB
Spi-B transcription factor (Spi-1/PU.1 related)
chr17_+_45778381 0.527 NM_022167
XYLT2
xylosyltransferase II
chr11_+_43920385 0.526 NM_001145033
C11orf96
chromosome 11 open reading frame 96
chr1_-_19089971 0.525 NM_001161504
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr15_+_38520594 0.523 NM_014952
BAHD1
bromo adjacent homology domain containing 1
chr2_+_222997456 0.522 SGPP2
sphingosine-1-phosphate phosphatase 2
chr19_-_12773591 0.521 NM_005809
NM_181738
PRDX2

peroxiredoxin 2

chr7_+_37926687 0.521 NM_017549
EPDR1
ependymin related protein 1 (zebrafish)
chr14_+_92459244 0.519 CHGA
chromogranin A (parathyroid secretory protein 1)
chr2_+_222997529 0.517 NM_152386
SGPP2
sphingosine-1-phosphate phosphatase 2
chr20_+_1132097 0.516 NM_001009612
C20orf202
chromosome 20 open reading frame 202
chr17_-_4747147 0.508 NM_000080
CHRNE
cholinergic receptor, nicotinic, epsilon
chr20_-_1922393 0.501 NM_001190900
PDYN
prodynorphin
chr5_+_271428 0.501 SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr5_-_45731976 0.500 NM_021072
HCN1
hyperpolarization activated cyclic nucleotide-gated potassium channel 1
chr22_-_48866484 0.498 NM_015166
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr22_+_40702709 0.490 NM_019106
NM_145733
SEPT3

septin 3

chr2_+_119905812 0.490 NM_183240
TMEM37
transmembrane protein 37
chr1_-_172153087 0.486 NM_000488
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr8_+_11599119 0.485 NM_002052
GATA4
GATA binding protein 4
chr22_-_22440054 0.481 NM_213720
CHCHD10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr22_+_30480848 0.481 NM_001136029
DEPDC5
DEP domain containing 5
chr6_+_31662454 0.470 NM_205837
LST1
leukocyte specific transcript 1
chr3_-_148605996 0.470 NM_001168379
ZIC4
Zic family member 4
chr9_-_99994704 0.466 NM_052820
CORO2A
coronin, actin binding protein, 2A
chr2_-_30883775 0.462 NM_144575
CAPN13
calpain 13
chr5_+_271441 0.454 SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr20_+_3000265 0.453 NM_000915
OXT
oxytocin, prepropeptide
chr12_+_119647953 0.452 NM_000017
ACADS
acyl-CoA dehydrogenase, C-2 to C-3 short chain
chr22_-_48865907 0.442 NM_139202
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr9_+_128607081 0.441 NM_001135776
NM_014007
ZBTB43

zinc finger and BTB domain containing 43

chr4_-_40212670 0.441 NM_019027
RBM47
RNA binding motif protein 47
chr3_+_130451160 0.439 COPG
coatomer protein complex, subunit gamma
chr4_+_7245218 0.431 NM_020777
SORCS2
sortilin-related VPS10 domain containing receptor 2
chr6_+_44418374 0.429 NM_145026
SPATS1
spermatogenesis associated, serine-rich 1
chr4_+_36923084 0.422 NM_001144990
KIAA1239
KIAA1239
chr7_+_138859213 0.416 NM_001080511
CLEC2L
C-type lectin domain family 2, member L
chr9_-_88064338 0.413 NM_001010907
C9orf153
chromosome 9 open reading frame 153
chr9_-_32540818 0.413 TOPORS
topoisomerase I binding, arginine/serine-rich, E3 ubiquitin protein ligase
chrX_-_53002900 0.411 NM_014138
FAM156A
family with sequence similarity 156, member A
chr11_+_22652957 0.409 GAS2
growth arrest-specific 2
chr22_-_48865980 0.408 MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr8_+_55533047 0.408 NM_022454
SOX17
SRY (sex determining region Y)-box 17
chr2_-_86871459 0.408 CD8A
CD8a molecule
chr18_-_42590989 0.407 NM_013305
ST8SIA5
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr20_+_3724905 0.404 CDC25B
cell division cycle 25 homolog B (S. pombe)
chr5_-_150517528 0.403 NM_001155
ANXA6
annexin A6
chr22_-_22646602 0.402 NM_001084392
DDT
D-dopachrome tautomerase
chr5_+_271447 0.401 SDHA
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr11_+_82545784 0.398 NM_015885
PCF11
PCF11, cleavage and polyadenylation factor subunit, homolog (S. cerevisiae)
chr8_-_93176819 0.393 RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_-_132704339 0.392 NM_007208
MRPL3
mitochondrial ribosomal protein L3
chr5_-_137938904 0.392 HSPA9
heat shock 70kDa protein 9 (mortalin)
chr8_-_100975041 0.392 COX6C
cytochrome c oxidase subunit VIc
chr5_-_150707281 0.386 NM_181776
SLC36A2
solute carrier family 36 (proton/amino acid symporter), member 2
chr2_+_218843358 0.385 NM_001077399
NM_015488
PNKD

paroxysmal nonkinesigenic dyskinesia

chr4_+_24406336 0.384 SOD3
superoxide dismutase 3, extracellular
chr11_+_10428799 0.382 NM_000480
AMPD3
adenosine monophosphate deaminase 3
chr3_-_50624085 0.381 CISH
cytokine inducible SH2-containing protein
chr1_+_119759076 0.379 NM_001166120
HSD3B2
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
chr2_+_6935246 0.378 NM_080657
RSAD2
radical S-adenosyl methionine domain containing 2
chr19_+_54621499 0.374 NM_001195256
LOC645971
hypothetical protein LOC645971
chr12_+_79362256 0.372 NM_001145026
PTPRQ
protein tyrosine phosphatase, receptor type, Q
chr12_-_16650697 0.371 NM_018640
LMO3
LIM domain only 3 (rhombotin-like 2)
chr4_-_1827475 0.369 NM_012318
LETM1
leucine zipper-EF-hand containing transmembrane protein 1
chrX_-_132376660 0.367 NM_001448
GPC4
glypican 4
chr9_-_116190038 0.366 AKNA
AT-hook transcription factor
chr2_-_86942504 0.365 NM_001178100
NM_004931
NM_172101
NM_172102
NM_172213
CD8B




CD8b molecule




chrX_-_21686079 0.363 NM_014332
SMPX
small muscle protein, X-linked
chr3_+_182900081 0.361 SOX2OT
SOX2 overlapping transcript (non-protein coding)
chr19_+_50863341 0.361 NM_000164
GIPR
gastric inhibitory polypeptide receptor
chr22_-_48865864 0.361 MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.23 2.90e-03 GO:0005886 plasma membrane
2.20 3.65e-03 GO:0071944 cell periphery
1.61 2.60e-02 GO:0016020 membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
202.70 2.42e-03 GO:0004111 creatine kinase activity