Motif ID: MAZ.p2

Z-value: 2.957


Transcription factors associated with MAZ.p2:

Gene SymbolEntrez IDGene Name
MAZ 4150 MYC-associated zinc finger protein (purine-binding transcription factor)



Activity profile for motif MAZ.p2.

activity profile for motif MAZ.p2


Sorted Z-values histogram for motif MAZ.p2

Sorted Z-values for motif MAZ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MAZ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_103525646 6.558 NM_006119
NM_033163
NM_033164
NM_033165
FGF8



fibroblast growth factor 8 (androgen-induced)



chr4_-_809879 6.253 NM_006651
CPLX1
complexin 1
chr19_+_659766 5.793 NM_001040134
NM_002579
PALM

paralemmin

chr6_-_94185780 4.669 NM_004440
EPHA7
EPH receptor A7
chr19_-_2672337 4.554 NM_145173
DIRAS1
DIRAS family, GTP-binding RAS-like 1
chr11_-_118739838 4.542 USP2
ubiquitin specific peptidase 2
chr7_-_158073121 4.264 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr5_-_134397740 4.234 NM_002653
PITX1
paired-like homeodomain 1
chr19_-_55524445 4.218 NM_004977
KCNC3
potassium voltage-gated channel, Shaw-related subfamily, member 3
chr4_-_5940893 4.016 CRMP1
collapsin response mediator protein 1
chr1_-_11674264 3.966 NM_001127325
MAD2L2
MAD2 mitotic arrest deficient-like 2 (yeast)
chr16_-_2186465 3.940 NM_020764
CASKIN1
CASK interacting protein 1
chr6_-_33268177 3.829 NM_001163771
NM_080679
NM_080680
NM_080681
COL11A2



collagen, type XI, alpha 2



chr13_-_113066202 3.815 GRTP1
growth hormone regulated TBC protein 1
chr4_-_5945596 3.695 NM_001014809
CRMP1
collapsin response mediator protein 1
chr19_-_242335 3.683 NM_003712
NM_177526
PPAP2C

phosphatidic acid phosphatase type 2C

chr11_+_56984702 3.608 NM_178570
RTN4RL2
reticulon 4 receptor-like 2
chr11_-_118740069 3.446 NM_171997
USP2
ubiquitin specific peptidase 2
chr7_+_5289079 3.428 NM_001040661
NM_153247
SLC29A4

solute carrier family 29 (nucleoside transporters), member 4

chr15_-_86600658 3.257 NM_001007156
NM_001012338
NM_002530
NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr1_-_233879617 3.250 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr8_-_144313100 3.238 NM_001135655
LY6H
lymphocyte antigen 6 complex, locus H
chr19_+_12810258 3.221 NM_014975
MAST1
microtubule associated serine/threonine kinase 1
chr21_+_45888001 3.169 PCBP3
poly(rC) binding protein 3
chr17_-_44047299 3.127 NM_024016
HOXB8
homeobox B8
chr13_+_87122778 3.120 NM_015567
SLITRK5
SLIT and NTRK-like family, member 5
chr4_-_5941043 3.115 CRMP1
collapsin response mediator protein 1
chr12_+_50686990 3.108 NM_181711
GRASP
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr11_+_359723 3.099 NM_178537
B4GALNT4
beta-1,4-N-acetyl-galactosaminyl transferase 4
chr22_+_38183480 3.049 MGAT3
mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr18_+_53253775 3.041 NM_004852
ONECUT2
one cut homeobox 2
chr6_+_99389300 3.039 NM_005604
POU3F2
POU class 3 homeobox 2
chr12_-_21818881 3.032 NM_004982
KCNJ8
potassium inwardly-rectifying channel, subfamily J, member 8
chr2_+_5750229 2.986 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr10_+_133850325 2.981 NM_006426
DPYSL4
dihydropyrimidinase-like 4
chr6_+_99389318 2.974 POU3F2
POU class 3 homeobox 2
chr13_-_113066366 2.913 NM_024719
GRTP1
growth hormone regulated TBC protein 1
chr5_-_134397470 2.829 PITX1
paired-like homeodomain 1
chr1_+_11674365 2.770 NM_198545
C1orf187
chromosome 1 open reading frame 187
chr19_-_16998449 2.720 NM_015692
CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chr3_-_47595190 2.708 NM_006574
CSPG5
chondroitin sulfate proteoglycan 5 (neuroglycan C)
chr12_-_56418295 2.686 NM_001122772
AGAP2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr10_+_134893766 2.658 NM_003577
UTF1
undifferentiated embryonic cell transcription factor 1
chr8_+_104582151 2.631 NM_001100117
RIMS2
regulating synaptic membrane exocytosis 2
chr19_+_540849 2.620 NM_001194
HCN2
hyperpolarization activated cyclic nucleotide-gated potassium channel 2
chr11_-_71632695 2.577 PHOX2A
paired-like homeobox 2a
chr11_+_17714070 2.533 NM_001112741
NM_004976
KCNC1

potassium voltage-gated channel, Shaw-related subfamily, member 1

chr4_-_111763655 2.511 NM_000325
PITX2
paired-like homeodomain 2
chr1_+_26609819 2.504 NM_024674
LIN28A
lin-28 homolog A (C. elegans)
chr5_+_139155569 2.465 NM_032289
PSD2
pleckstrin and Sec7 domain containing 2
chr1_+_2975590 2.435 NM_022114
NM_199454
PRDM16

PR domain containing 16

chr4_-_1156362 2.424 SPON2
spondin 2, extracellular matrix protein
chr19_-_55763091 2.405 NM_001080457
LRRC4B
leucine rich repeat containing 4B
chr19_-_772966 2.404 LPPR3
lipid phosphate phosphatase-related protein type 3
chr8_-_144313053 2.402 LY6H
lymphocyte antigen 6 complex, locus H
chr4_-_1156458 2.393 SPON2
spondin 2, extracellular matrix protein
chr19_-_772913 2.392 NM_024888
LPPR3
lipid phosphate phosphatase-related protein type 3
chr19_+_40325993 2.376 NM_022006
FXYD7
FXYD domain containing ion transport regulator 7
chrX_+_9392980 2.352 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr16_-_265868 2.350 NM_003834
NM_183337
RGS11

regulator of G-protein signaling 11

chr10_-_88116181 2.336 NM_017551
GRID1
glutamate receptor, ionotropic, delta 1
chr4_-_1156378 2.321 SPON2
spondin 2, extracellular matrix protein
chr16_-_2776606 2.319 NM_152891
PRSS33
protease, serine, 33
chr4_-_1156533 2.316 NM_012445
SPON2
spondin 2, extracellular matrix protein
chr20_-_3097070 2.300 NM_014731
ProSAPiP1
ProSAPiP1 protein
chr9_+_70509925 2.271 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr17_+_40089270 2.263 NM_001145080
C17orf104
chromosome 17 open reading frame 104
chr21_+_42946719 2.254 NM_001001567
NM_001001568
NM_001001569
NM_001001570
NM_001001571
NM_001001572
NM_001001573
NM_001001574
NM_001001575
NM_001001576
NM_001001577
NM_001001578
NM_001001579
NM_001001580
NM_001001581
NM_001001582
NM_001001583
NM_001001584
NM_001001585
NM_002606
PDE9A



















phosphodiesterase 9A



















chr1_+_41022066 2.252 NM_004700
NM_172163
KCNQ4

potassium voltage-gated channel, KQT-like subfamily, member 4

chr2_+_10101081 2.242 NM_003597
NM_001177716
KLF11

Kruppel-like factor 11

chr21_-_43368963 2.234 NM_000071
CBS
cystathionine-beta-synthase
chr8_+_26427378 2.209 NM_001197293
DPYSL2
dihydropyrimidinase-like 2
chr10_+_102495327 2.206 NM_000278
NM_003987
NM_003988
NM_003989
NM_003990
PAX2




paired box 2




chr11_-_69228286 2.196 NM_005117
FGF19
fibroblast growth factor 19
chr4_-_5941167 2.188 NM_001313
CRMP1
collapsin response mediator protein 1
chr19_-_53706644 2.181


chr22_+_43476710 2.171 NM_181333
PRR5
proline rich 5 (renal)
chr2_-_219558517 2.143 NM_017521
FEV
FEV (ETS oncogene family)
chr13_+_99431417 2.143


chr1_+_26609893 2.136 LIN28A
lin-28 homolog A (C. elegans)
chr17_+_26742767 2.120 NM_032932
RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr20_-_47532585 2.115 NM_004975
KCNB1
potassium voltage-gated channel, Shab-related subfamily, member 1
chr1_-_50661716 2.113 NM_032110
DMRTA2
DMRT-like family A2
chr11_-_71632864 2.107 NM_005169
PHOX2A
paired-like homeobox 2a
chr9_-_121171400 2.104 NM_014618
DBC1
deleted in bladder cancer 1
chr12_+_93066370 2.102 NM_005761
PLXNC1
plexin C1
chr1_-_29322993 2.099 NM_001003682
TMEM200B
transmembrane protein 200B
chr19_-_2979901 2.078 NM_003260
TLE2
transducin-like enhancer of split 2 (E(sp1) homolog, Drosophila)
chr20_+_60918836 2.077 NM_001853
COL9A3
collagen, type IX, alpha 3
chr17_-_72045218 2.067 NM_134268
CYGB
cytoglobin
chr17_-_34014390 2.064 SRCIN1
SRC kinase signaling inhibitor 1
chr17_+_62391216 2.058 NM_014405
CACNG4
calcium channel, voltage-dependent, gamma subunit 4
chr16_-_51138306 2.050 NM_001080430
TOX3
TOX high mobility group box family member 3
chr11_-_64268841 2.040 NM_001098670
RASGRP2
RAS guanyl releasing protein 2 (calcium and DAG-regulated)
chr5_-_63293715 2.040 HTR1A
5-hydroxytryptamine (serotonin) receptor 1A
chr8_-_26427304 2.032 NM_007257
PNMA2
paraneoplastic antigen MA2
chr4_-_111763356 2.031 PITX2
paired-like homeodomain 2
chr15_-_63457378 2.031 NM_004884
IGDCC3
immunoglobulin superfamily, DCC subclass, member 3
chr11_+_113435506 2.027 ZBTB16
zinc finger and BTB domain containing 16
chr8_-_144313293 2.026 NM_001130478
LY6H
lymphocyte antigen 6 complex, locus H
chr3_-_193609531 2.026 NM_021032
FGF12
fibroblast growth factor 12
chr5_+_170668892 2.022 NM_021025
TLX3
T-cell leukemia homeobox 3
chr10_+_124897627 2.016 NM_005519
HMX2
H6 family homeobox 2
chr4_-_6253152 2.015 NM_001099433
NM_144720
JAKMIP1

janus kinase and microtubule interacting protein 1

chr1_-_29321599 2.012 NM_001171868
TMEM200B
transmembrane protein 200B
chr19_+_38979502 2.000 NM_001129994
NM_001129995
NM_024076
KCTD15


potassium channel tetramerisation domain containing 15


chr3_+_12813170 1.999 NM_001162499
NM_012298
CAND2

cullin-associated and neddylation-dissociated 2 (putative)

chr18_+_75256954 1.998 NFATC1
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 1
chr16_+_1143241 1.991 NM_001005407
NM_021098
CACNA1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

chr11_+_113435640 1.974 NM_006006
ZBTB16
zinc finger and BTB domain containing 16
chr10_-_118021532 1.970 NM_145793
GFRA1
GDNF family receptor alpha 1
chr14_+_89597860 1.965 NM_022054
KCNK13
potassium channel, subfamily K, member 13
chr2_-_100087366 1.964 AFF3
AF4/FMR2 family, member 3
chr17_+_75366524 1.955 NM_005189
NM_032647
CBX2

chromobox homolog 2

chr2_+_104837004 1.944


chr18_-_28606839 1.938 NM_020805
KLHL14
kelch-like 14 (Drosophila)
chr9_-_95757448 1.895 BARX1
BARX homeobox 1
chr17_-_37586716 1.893 NM_012285
KCNH4
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr3_+_53504070 1.889 NM_000720
NM_001128839
NM_001128840
CACNA1D


calcium channel, voltage-dependent, L type, alpha 1D subunit


chr19_-_19233370 1.885 HAPLN4
hyaluronan and proteoglycan link protein 4
chr19_-_52666886 1.884 SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr14_+_95412481 1.871


chr19_-_16868674 1.867 CPAMD8
C3 and PZP-like, alpha-2-macroglobulin domain containing 8
chrX_-_134883798 1.864 NM_173470
MMGT1
membrane magnesium transporter 1
chr17_+_26742903 1.863 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr16_+_1323627 1.853 BAIAP3
BAI1-associated protein 3
chrX_+_144707022 1.845 NM_001144003
NM_001144004
NM_001144005
NM_032539
SLITRK2



SLIT and NTRK-like family, member 2



chr2_+_42128521 1.841 NM_138370
PKDCC
protein kinase domain containing, cytoplasmic homolog (mouse)
chr1_-_1465602 1.837 NM_001114748
C1orf70
chromosome 1 open reading frame 70
chr7_-_44152252 1.836 GCK
glucokinase (hexokinase 4)
chr8_+_65656164 1.835 BHLHE22
basic helix-loop-helix family, member e22
chr5_+_3649167 1.835 NM_024337
IRX1
iroquois homeobox 1
chr3_-_140148671 1.828 NM_023067
FOXL2
forkhead box L2
chr14_-_20562962 1.827 NM_201538
NM_201539
NM_201540
NM_201541
NDRG2



NDRG family member 2



chr4_+_995395 1.820 FGFRL1
fibroblast growth factor receptor-like 1
chr2_-_200030412 1.801 SATB2
SATB homeobox 2
chr1_+_154878498 1.801 BCAN
brevican
chr1_-_40903700 1.798 RIMS3
regulating synaptic membrane exocytosis 3
chr7_-_27206249 1.798 NM_000522
HOXA13
homeobox A13
chr7_-_44152232 1.797 GCK
glucokinase (hexokinase 4)
chr11_+_2422747 1.792 NM_000218
KCNQ1
potassium voltage-gated channel, KQT-like subfamily, member 1
chr12_+_56291484 1.785 NM_182947
ARHGEF25
Rho guanine nucleotide exchange factor (GEF) 25
chr7_-_72822471 1.777 NM_001306
CLDN3
claudin 3
chr12_+_52618815 1.763 NM_017410
HOXC13
homeobox C13
chr11_-_69343128 1.757 NM_005247
FGF3
fibroblast growth factor 3
chr5_-_16232896 1.756 NM_001102562
MARCH11
membrane-associated ring finger (C3HC4) 11
chr19_+_447453 1.753 NM_130760
NM_130762
MADCAM1

mucosal vascular addressin cell adhesion molecule 1

chr21_-_43369492 1.752 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chr3_-_129689394 1.747 NM_001145662
GATA2
GATA binding protein 2
chr20_+_55359551 1.737 NM_003610
RAE1
RAE1 RNA export 1 homolog (S. pombe)
chrX_+_150095713 1.737 NM_004224
GPR50
G protein-coupled receptor 50
chr10_-_28074752 1.733 NM_173576
MKX
mohawk homeobox
chr7_-_19123765 1.731 TWIST1
twist homolog 1 (Drosophila)
chr11_-_6633427 1.731 NM_003737
DCHS1
dachsous 1 (Drosophila)
chr10_+_94823636 1.718 NM_000783
CYP26A1
cytochrome P450, family 26, subfamily A, polypeptide 1
chr20_-_61755145 1.715 NM_015894
STMN3
stathmin-like 3
chr6_-_165996031 1.715 LOC100132188
LP7097
chrX_+_128942435 1.713


chr2_+_210344945 1.711 NM_032504
NM_182587
UNC80

unc-80 homolog (C. elegans)

chr17_+_26839143 1.711 RAB11FIP4
RAB11 family interacting protein 4 (class II)
chr19_-_242168 1.710 NM_177543
PPAP2C
phosphatidic acid phosphatase type 2C
chr12_+_56230047 1.706 KIF5A
kinesin family member 5A
chr3_-_10724715 1.703 ATP2B2
ATPase, Ca++ transporting, plasma membrane 2
chr19_-_55914837 1.694


chr22_+_43476755 1.692 NM_181334
PRR5-ARHGAP8
PRR5
PRR5-ARHGAP8 readthrough
proline rich 5 (renal)
chr13_-_101366995 1.691 NM_004115
FGF14
fibroblast growth factor 14
chr10_+_94439658 1.687 NM_002729
HHEX
hematopoietically expressed homeobox
chr17_-_7138535 1.682 YBX2
Y box binding protein 2
chr14_+_105024576 1.651 CRIP1
cysteine-rich protein 1 (intestinal)
chr17_+_78630793 1.643 NM_001004431
METRNL
meteorin, glial cell differentiation regulator-like
chr22_+_48951286 1.636 NM_001160300
NM_052839
PANX2

pannexin 2

chr1_+_63561632 1.636 FOXD3
forkhead box D3
chr12_+_4889309 1.630 NM_000217
KCNA1
potassium voltage-gated channel, shaker-related subfamily, member 1 (episodic ataxia with myokymia)
chr17_+_44429748 1.611 NM_001160423
NM_006546
IGF2BP1

insulin-like growth factor 2 mRNA binding protein 1

chr5_-_146237826 1.608 PPP2R2B
protein phosphatase 2, regulatory subunit B, beta
chr2_+_171280182 1.600


chr19_+_1397268 1.598 APC2
adenomatosis polyposis coli 2
chr1_-_99242765 1.597 NM_001010861
NM_001037317
LPPR5

lipid phosphate phosphatase-related protein type 5

chr14_-_94306104 1.594 NM_173849
GSC
goosecoid homeobox
chr11_-_40271086 1.587 LRRC4C
leucine rich repeat containing 4C
chr10_+_83625049 1.587 NM_001010848
NM_001165972
NRG3

neuregulin 3

chr11_+_279113 1.587 NM_025092
ATHL1
ATH1, acid trehalase-like 1 (yeast)
chr22_+_27798887 1.587 NM_001039570
NM_032045
KREMEN1

kringle containing transmembrane protein 1

chr7_-_19123787 1.586 NM_000474
TWIST1
twist homolog 1 (Drosophila)
chr14_+_105024301 1.585 NM_001311
CRIP1
cysteine-rich protein 1 (intestinal)
chr1_+_21708502 1.584 ALPL
alkaline phosphatase, liver/bone/kidney
chr16_-_695719 1.583 NM_153350
FBXL16
F-box and leucine-rich repeat protein 16
chr16_-_47872880 1.580


chr3_-_166397142 1.574 NM_014926
SLITRK3
SLIT and NTRK-like family, member 3
chr1_+_154878344 1.571 NM_021948
NM_198427
BCAN

brevican

chr16_+_53522611 1.571 NM_005853
IRX5
iroquois homeobox 5
chr3_-_42282665 1.568 NM_000729
CCK
cholecystokinin
chr1_+_1971762 1.560 NM_002744
PRKCZ
protein kinase C, zeta
chr17_-_1029758 1.560 NM_021962
ABR
active BCR-related gene
chr17_+_35036704 1.557 NM_032192
PPP1R1B
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr19_-_13478037 1.552 NM_000068
NM_001127221
NM_001127222
NM_001174080
NM_023035
CACNA1A




calcium channel, voltage-dependent, P/Q type, alpha 1A subunit




chr8_+_1699418 1.551 CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr15_+_39739864 1.545 NM_001080541
NM_001164273
MGA

MAX gene associated

chr22_+_47350781 1.544 NM_015381
FAM19A5
family with sequence similarity 19 (chemokine (C-C motif)-like), member A5
chr9_-_139068269 1.541 NM_001246
NM_203468
ENTPD2

ectonucleoside triphosphate diphosphohydrolase 2


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.93 3.41e-35 GO:0007399 nervous system development
2.78 3.45e-32 GO:0048731 system development
2.61 8.22e-31 GO:0048856 anatomical structure development
2.46 4.09e-29 GO:0007275 multicellular organismal development
2.34 5.59e-28 GO:0032502 developmental process
1.98 2.52e-25 GO:0032501 multicellular organismal process
2.92 3.00e-24 GO:0030154 cell differentiation
2.84 3.51e-23 GO:0048869 cellular developmental process
4.21 6.40e-22 GO:0048699 generation of neurons
4.03 4.02e-21 GO:0022008 neurogenesis
3.09 3.00e-19 GO:0009653 anatomical structure morphogenesis
4.37 8.40e-19 GO:0030182 neuron differentiation
2.75 2.41e-18 GO:0048513 organ development
3.70 2.02e-17 GO:0048468 cell development
4.63 4.48e-15 GO:0007417 central nervous system development
4.21 1.79e-14 GO:0009887 organ morphogenesis
1.50 5.81e-13 GO:0065007 biological regulation
1.53 5.86e-13 GO:0050789 regulation of biological process
1.55 2.02e-12 GO:0050794 regulation of cellular process
4.04 2.03e-12 GO:0048666 neuron development
4.26 6.49e-12 GO:0031175 neuron projection development
2.11 7.66e-12 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.21 9.49e-12 GO:0000904 cell morphogenesis involved in differentiation
3.76 1.40e-11 GO:0032989 cellular component morphogenesis
4.78 2.42e-11 GO:0048598 embryonic morphogenesis
2.05 5.98e-11 GO:0051171 regulation of nitrogen compound metabolic process
4.32 1.01e-10 GO:0048667 cell morphogenesis involved in neuron differentiation
4.24 1.73e-10 GO:0048812 neuron projection morphogenesis
3.71 1.78e-10 GO:0000902 cell morphogenesis
4.60 4.13e-10 GO:0007420 brain development
4.71 4.90e-10 GO:0007389 pattern specification process
4.23 8.88e-10 GO:0007409 axonogenesis
3.87 1.39e-09 GO:0048858 cell projection morphogenesis
3.34 1.78e-09 GO:0009790 embryo development
3.84 1.82e-09 GO:0032990 cell part morphogenesis
2.10 2.95e-09 GO:0051252 regulation of RNA metabolic process
3.34 3.23e-09 GO:0031327 negative regulation of cellular biosynthetic process
2.11 5.85e-09 GO:0006355 regulation of transcription, DNA-dependent
3.27 6.55e-09 GO:0009890 negative regulation of biosynthetic process
3.38 7.16e-09 GO:0030030 cell projection organization
1.96 1.29e-08 GO:0031326 regulation of cellular biosynthetic process
2.94 1.86e-08 GO:0009888 tissue development
4.09 2.21e-08 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
1.94 2.51e-08 GO:0009889 regulation of biosynthetic process
1.77 4.18e-08 GO:0080090 regulation of primary metabolic process
1.76 4.79e-08 GO:0031323 regulation of cellular metabolic process
2.75 4.80e-08 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.05 9.86e-08 GO:0048523 negative regulation of cellular process
1.97 1.13e-07 GO:2000112 regulation of cellular macromolecule biosynthetic process
5.03 1.22e-07 GO:0003002 regionalization
3.47 1.29e-07 GO:0045892 negative regulation of transcription, DNA-dependent
1.92 1.89e-07 GO:0010468 regulation of gene expression
2.68 1.93e-07 GO:0009892 negative regulation of metabolic process
1.94 1.99e-07 GO:0010556 regulation of macromolecule biosynthetic process
2.81 2.26e-07 GO:0040011 locomotion
3.40 2.29e-07 GO:0051253 negative regulation of RNA metabolic process
3.25 2.49e-07 GO:0010629 negative regulation of gene expression
3.21 3.60e-07 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.96 3.61e-07 GO:0048519 negative regulation of biological process
4.35 4.95e-07 GO:0048729 tissue morphogenesis
3.17 5.16e-07 GO:0051172 negative regulation of nitrogen compound metabolic process
4.87 5.93e-07 GO:0048568 embryonic organ development
3.15 6.32e-07 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
3.09 6.41e-07 GO:0010558 negative regulation of macromolecule biosynthetic process
2.70 8.23e-07 GO:0031324 negative regulation of cellular metabolic process
4.09 8.92e-07 GO:0007411 axon guidance
4.78 1.97e-06 GO:0002009 morphogenesis of an epithelium
1.64 3.13e-06 GO:0019222 regulation of metabolic process
2.61 3.73e-06 GO:0010605 negative regulation of macromolecule metabolic process
3.33 4.06e-06 GO:0019226 transmission of nerve impulse
3.33 4.06e-06 GO:0035637 multicellular organismal signaling
2.50 4.79e-06 GO:0007154 cell communication
2.77 5.28e-06 GO:0007267 cell-cell signaling
5.51 6.68e-06 GO:0006813 potassium ion transport
3.94 8.31e-06 GO:0001501 skeletal system development
5.08 9.73e-06 GO:0035239 tube morphogenesis
3.62 1.27e-05 GO:0060429 epithelium development
2.25 1.28e-05 GO:0051239 regulation of multicellular organismal process
1.68 1.36e-05 GO:0060255 regulation of macromolecule metabolic process
5.53 1.69e-05 GO:0060562 epithelial tube morphogenesis
5.08 2.47e-05 GO:0030900 forebrain development
3.23 2.58e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
5.31 3.15e-05 GO:0048562 embryonic organ morphogenesis
3.28 5.93e-05 GO:0007268 synaptic transmission
9.90 6.54e-05 GO:0021510 spinal cord development
2.81 8.93e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.59 9.72e-05 GO:0023052 signaling
7.64 2.35e-04 GO:0009953 dorsal/ventral pattern formation
3.77 2.94e-04 GO:0035295 tube development
2.29 3.62e-04 GO:0009605 response to external stimulus
3.72 3.79e-04 GO:0007423 sensory organ development
2.62 4.68e-04 GO:0051254 positive regulation of RNA metabolic process
1.20 4.85e-04 GO:0009987 cellular process
2.89 5.06e-04 GO:0006935 chemotaxis
2.89 5.06e-04 GO:0042330 taxis
1.94 5.46e-04 GO:0023051 regulation of signaling
4.92 5.83e-04 GO:0045165 cell fate commitment
2.60 5.87e-04 GO:0010628 positive regulation of gene expression
2.36 6.63e-04 GO:0006351 transcription, DNA-dependent
2.49 7.10e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
17.45 8.57e-04 GO:0021522 spinal cord motor neuron differentiation
6.65 1.01e-03 GO:0021953 central nervous system neuron differentiation
4.16 1.08e-03 GO:0045664 regulation of neuron differentiation
3.30 1.48e-03 GO:0044057 regulation of system process
15.51 1.91e-03 GO:0021517 ventral spinal cord development
3.61 2.18e-03 GO:0045596 negative regulation of cell differentiation
2.87 2.29e-03 GO:0048646 anatomical structure formation involved in morphogenesis
2.92 2.70e-03 GO:0032583 regulation of gene-specific transcription
14.69 2.75e-03 GO:0072073 kidney epithelium development
2.38 2.93e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
4.07 3.10e-03 GO:0032582 negative regulation of gene-specific transcription
3.26 3.23e-03 GO:0051093 negative regulation of developmental process
4.05 3.33e-03 GO:0007517 muscle organ development
3.64 3.60e-03 GO:0050767 regulation of neurogenesis
10.86 3.62e-03 GO:0021515 cell differentiation in spinal cord
3.42 4.95e-03 GO:0051960 regulation of nervous system development
2.31 5.73e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
2.34 6.18e-03 GO:2000026 regulation of multicellular organismal development
4.34 6.21e-03 GO:0010553 negative regulation of gene-specific transcription from RNA polymerase II promoter
17.89 6.73e-03 GO:0072028 nephron morphogenesis
5.50 6.76e-03 GO:0007626 locomotory behavior
4.23 8.44e-03 GO:0009952 anterior/posterior pattern formation
2.97 8.44e-03 GO:0009792 embryo development ending in birth or egg hatching
2.13 8.47e-03 GO:0032774 RNA biosynthetic process
3.17 8.62e-03 GO:0060284 regulation of cell development
2.21 1.05e-02 GO:0031328 positive regulation of cellular biosynthetic process
7.45 1.41e-02 GO:0001764 neuron migration
15.51 1.52e-02 GO:0060441 epithelial tube branching involved in lung morphogenesis
15.51 1.52e-02 GO:0072009 nephron epithelium development
2.18 1.52e-02 GO:0009891 positive regulation of biosynthetic process
3.04 1.56e-02 GO:0015672 monovalent inorganic cation transport
8.80 1.61e-02 GO:0001708 cell fate specification
5.02 1.66e-02 GO:0001822 kidney development
2.14 1.67e-02 GO:0006811 ion transport
6.25 1.73e-02 GO:0010001 glial cell differentiation
4.58 1.74e-02 GO:0001763 morphogenesis of a branching structure
4.97 1.83e-02 GO:0061138 morphogenesis of a branching epithelium
3.24 1.87e-02 GO:0061061 muscle structure development
2.90 1.94e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
1.65 2.00e-02 GO:0042221 response to chemical stimulus
2.87 2.32e-02 GO:0043009 chordate embryonic development
4.83 2.40e-02 GO:0072001 renal system development
3.05 2.49e-02 GO:0007610 behavior
4.40 2.62e-02 GO:0042391 regulation of membrane potential
3.81 2.80e-02 GO:0035270 endocrine system development
13.68 3.01e-02 GO:0060993 kidney morphogenesis
4.70 3.13e-02 GO:0043583 ear development
9.97 3.24e-02 GO:0072006 nephron development
2.28 3.74e-02 GO:0045595 regulation of cell differentiation
9.63 4.01e-02 GO:0071804 cellular potassium ion transport
9.63 4.01e-02 GO:0071805 potassium ion transmembrane transport

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
7.24 2.75e-10 GO:0034703 cation channel complex
3.85 1.75e-08 GO:0045202 synapse
5.15 3.09e-08 GO:0034702 ion channel complex
8.02 1.06e-07 GO:0008076 voltage-gated potassium channel complex
8.02 1.06e-07 GO:0034705 potassium channel complex
4.22 1.58e-07 GO:0044456 synapse part
4.93 1.08e-06 GO:0030425 dendrite
3.39 4.43e-06 GO:0043005 neuron projection
6.74 1.41e-04 GO:0033267 axon part
1.73 2.50e-04 GO:0044459 plasma membrane part
4.21 3.20e-04 GO:0030424 axon
1.44 2.14e-03 GO:0005886 plasma membrane
1.42 4.30e-03 GO:0071944 cell periphery
11.08 1.48e-02 GO:0005891 voltage-gated calcium channel complex
3.54 1.89e-02 GO:0043025 neuronal cell body
4.03 2.06e-02 GO:0031225 anchored to membrane
3.44 2.53e-02 GO:0044297 cell body
2.49 2.87e-02 GO:0044463 cell projection part
1.93 4.61e-02 GO:0042995 cell projection

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
4.31 1.63e-19 GO:0043565 sequence-specific DNA binding
3.47 4.85e-18 GO:0030528 transcription regulator activity
3.34 5.45e-16 GO:0001071 nucleic acid binding transcription factor activity
3.34 5.45e-16 GO:0003700 sequence-specific DNA binding transcription factor activity
8.52 1.16e-14 GO:0022843 voltage-gated cation channel activity
6.72 1.41e-12 GO:0005244 voltage-gated ion channel activity
6.72 1.41e-12 GO:0022832 voltage-gated channel activity
5.29 2.90e-11 GO:0005261 cation channel activity
4.28 1.41e-10 GO:0005216 ion channel activity
4.79 1.60e-10 GO:0022836 gated channel activity
4.21 2.23e-10 GO:0022838 substrate-specific channel activity
4.08 5.39e-10 GO:0015267 channel activity
4.07 5.79e-10 GO:0022803 passive transmembrane transporter activity
8.07 8.81e-09 GO:0005249 voltage-gated potassium channel activity
1.96 3.04e-08 GO:0003677 DNA binding
6.65 6.53e-08 GO:0005267 potassium channel activity
3.03 1.87e-06 GO:0008324 cation transmembrane transporter activity
4.80 2.28e-06 GO:0010843 promoter binding
2.70 2.59e-06 GO:0015075 ion transmembrane transporter activity
4.61 4.56e-06 GO:0000975 regulatory region DNA binding
4.61 4.56e-06 GO:0001067 regulatory region nucleic acid binding
4.61 4.56e-06 GO:0044212 transcription regulatory region DNA binding
3.75 4.86e-06 GO:0016563 transcription activator activity
3.72 1.10e-05 GO:0016564 transcription repressor activity
2.42 2.46e-05 GO:0022891 substrate-specific transmembrane transporter activity
2.25 1.94e-04 GO:0022857 transmembrane transporter activity
12.53 2.72e-04 GO:0005245 voltage-gated calcium channel activity
2.13 5.96e-04 GO:0022892 substrate-specific transporter activity
7.61 6.96e-04 GO:0008301 DNA bending activity
1.53 1.14e-03 GO:0003676 nucleic acid binding
5.54 3.70e-03 GO:0003705 sequence-specific enhancer binding RNA polymerase II transcription factor activity
5.17 6.84e-03 GO:0003704 specific RNA polymerase II transcription factor activity
1.88 8.48e-03 GO:0005215 transporter activity
5.00 9.12e-03 GO:0000981 sequence-specific DNA binding RNA polymerase II transcription factor activity
4.14 1.04e-02 GO:0003690 double-stranded DNA binding
4.80 1.32e-02 GO:0016566 specific transcriptional repressor activity
3.52 1.44e-02 GO:0043566 structure-specific DNA binding
2.90 1.72e-02 GO:0008134 transcription factor binding
3.03 2.65e-02 GO:0003702 RNA polymerase II transcription factor activity