Motif ID: NANOG.p2

Z-value: 0.937


Transcription factors associated with NANOG.p2:

Gene SymbolEntrez IDGene Name
NANOG 79923 Nanog homeobox



Activity profile for motif NANOG.p2.

activity profile for motif NANOG.p2


Sorted Z-values histogram for motif NANOG.p2

Sorted Z-values for motif NANOG.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of NANOG.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_40632456 1.006 NM_005306
FFAR2
free fatty acid receptor 2
chr18_+_18989786 0.838 NM_138375
CABLES1
Cdk5 and Abl enzyme substrate 1
chr3_-_71860958 0.783 NM_001134650
EIF4E3
eukaryotic translation initiation factor 4E family member 3
chr1_-_109957195 0.764 NM_005272
GNAT2
guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2
chr6_+_131613196 0.758 NM_004842
NM_138633
AKAP7

A kinase (PRKA) anchor protein 7

chr1_-_116185215 0.719 NM_005599
NHLH2
nescient helix loop helix 2
chr12_-_51114372 0.687 NM_004693
KRT75
keratin 75
chr4_-_186815116 0.664 NM_001145674
NM_001145675
SORBS2

sorbin and SH3 domain containing 2

chr2_+_157822355 0.652 NM_014568
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr10_-_14412813 0.647 NM_018027
FRMD4A
FERM domain containing 4A
chr4_+_71806538 0.641 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr21_+_43024936 0.639 PDE9A
phosphodiesterase 9A
chr13_+_97856148 0.634


chr2_-_98646367 0.624 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr7_-_96471544 0.575 DLX6-AS1
DLX6 antisense RNA 1 (non-protein coding)
chr3_+_130730171 0.547 NM_000539
RHO
rhodopsin
chr12_-_108736983 0.520 NM_001177431
NM_001177428
NM_001177433
NM_147204
TRPV4



transient receptor potential cation channel, subfamily V, member 4



chr7_-_13992351 0.519 NM_001163150
NM_001163151
NM_001163152
ETV1


ets variant 1


chr6_-_42798286 0.515 NM_000322
PRPH2
peripherin 2 (retinal degeneration, slow)
chr3_-_11598829 0.508 NM_001128220
VGLL4
vestigial like 4 (Drosophila)
chr2_+_17861266 0.494 NM_001105569
MSGN1
mesogenin 1
chr8_+_67201684 0.490 NM_033058
NM_184085
NM_184086
NM_184087
TRIM55



tripartite motif containing 55



chr12_-_6103945 0.477 NM_000552
VWF
von Willebrand factor
chrX_-_19727828 0.458 NM_001024666
SH3KBP1
SH3-domain kinase binding protein 1
chr7_+_128802719 0.457 NM_001130722
AHCYL2
adenosylhomocysteinase-like 2
chr11_-_17147863 0.453 NM_002645
PIK3C2A
phosphoinositide-3-kinase, class 2, alpha polypeptide
chr19_+_53016910 0.451 NM_000554
CRX
cone-rod homeobox
chr7_-_36992221 0.449 NM_130442
ELMO1
engulfment and cell motility 1
chr15_-_53350383 0.448 NM_183236
RAB27A
RAB27A, member RAS oncogene family
chr7_+_116238309 0.443 CAPZA2
capping protein (actin filament) muscle Z-line, alpha 2
chr11_-_58736897 0.435 NM_001039396
MPEG1
macrophage expressed 1
chr7_+_141054621 0.433 NM_001105558
WEE2
WEE1 homolog 2 (S. pombe)
chr5_-_168204430 0.433


chr1_-_230717850 0.430 NM_020808
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr16_+_6763810 0.425 NM_001142334
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr5_+_140703784 0.425 NM_018916
NM_032011
PCDHGA3

protocadherin gamma subfamily A, 3

chr1_-_153109349 0.418 NM_002249
KCNN3
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 3
chr21_-_30836051 0.410 NM_181612
KRTAP19-6
keratin associated protein 19-6
chr9_-_132759045 0.408 NM_198180
QRFP
pyroglutamylated RFamide peptide
chr11_-_40272239 0.408 NM_020929
LRRC4C
leucine rich repeat containing 4C
chr16_+_6473759 0.406 RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr11_+_7574992 0.383 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr15_-_91078307 0.382 FAM174B
family with sequence similarity 174, member B
chr9_-_5294579 0.381 NM_005059
NM_134441
RLN2

relaxin 2

chr18_+_13601664 0.379 NM_001003674
NM_001003675
C18orf1

chromosome 18 open reading frame 1

chr4_+_3341521 0.373 NM_198227
RGS12
regulator of G-protein signaling 12
chr17_-_44400952 0.373 NM_004123
GIP
gastric inhibitory polypeptide
chr1_+_559618 0.367


chr3_+_161040343 0.366 NM_001197109
SCHIP1
schwannomin interacting protein 1
chr5_+_127012611 0.364 NM_001048252
CTXN3
cortexin 3
chr1_-_42156957 0.364 HIVEP3
human immunodeficiency virus type I enhancer binding protein 3
chr1_-_30977931 0.363 LAPTM5
lysosomal protein transmembrane 5
chr1_+_154386358 0.362 NM_001193301
SEMA4A
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A
chr3_+_161040439 0.361 SCHIP1
schwannomin interacting protein 1
chr1_+_15862887 0.355


chr2_+_96269703 0.354 NM_001037228
LOC285033
hypothetical protein LOC285033
chr9_+_115265827 0.348 NM_017790
RGS3
regulator of G-protein signaling 3
chr12_+_45896511 0.348 FAM113B
family with sequence similarity 113, member B
chr6_+_88026338 0.344 ZNF292
zinc finger protein 292
chr1_-_50661716 0.344 NM_032110
DMRTA2
DMRT-like family A2
chr17_-_36418869 0.342 NM_031958
KRTAP3-1
keratin associated protein 3-1
chr4_+_77575276 0.342 NM_020859
SHROOM3
shroom family member 3
chr20_+_43691797 0.341 NM_080753
WFDC10A
WAP four-disulfide core domain 10A
chr1_+_42934910 0.338 YBX1
Y box binding protein 1
chr21_-_26294332 0.338 APP
amyloid beta (A4) precursor protein
chr1_-_42156913 0.336


chr15_-_53349775 0.334 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr1_+_196874839 0.333 PTPRC
protein tyrosine phosphatase, receptor type, C
chr12_-_14740694 0.331 NM_004963
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr5_+_176744037 0.331 NM_001167579
NM_003052
SLC34A1

solute carrier family 34 (sodium phosphate), member 1

chr3_-_21767819 0.330 NM_024697
ZNF385D
zinc finger protein 385D
chrX_-_19727775 0.328 SH3KBP1
SH3-domain kinase binding protein 1
chr1_-_42157077 0.328 NM_001127714
NM_024503
HIVEP3

human immunodeficiency virus type I enhancer binding protein 3

chr3_+_63859114 0.325 NM_001177387
ATXN7
ataxin 7
chr10_+_11246934 0.325 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr10_-_74384485 0.324 NM_032562
PLA2G12B
phospholipase A2, group XIIB
chr5_+_125786975 0.318 GRAMD3
GRAM domain containing 3
chr4_-_40631397 0.316 APBB2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr18_-_50134940 0.312 NM_139171
STARD6
StAR-related lipid transfer (START) domain containing 6
chr2_-_110665188 0.308 NM_033514
LIMS3-LOC440895
LIMS3
LIMS3-LOC440895 read-through
LIM and senescent cell antigen-like domains 3
chr1_-_154484341 0.306 NM_198406
NM_024897
PAQR6

progestin and adipoQ receptor family member VI

chr1_-_120285753 0.305 NOTCH2
notch 2
chr7_+_104468614 0.305 MLL5
myeloid/lymphoid or mixed-lineage leukemia 5 (trithorax homolog, Drosophila)
chr6_+_34314545 0.301 NM_145905
HMGA1
high mobility group AT-hook 1
chr5_+_140848905 0.298 NM_018929
NM_032407
PCDHGC5

protocadherin gamma subfamily C, 5

chr8_-_40874485 0.297 NM_001135731
NM_024645
ZMAT4

zinc finger, matrin-type 4

chr1_+_20489998 0.293 NM_001039500
VWA5B1
von Willebrand factor A domain containing 5B1
chr3_-_116272911 0.288 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr16_+_8714326 0.279 NM_000663
ABAT
4-aminobutyrate aminotransferase
chr7_-_107930170 0.278 PNPLA8
patatin-like phospholipase domain containing 8
chr6_+_143971009 0.277 NM_001100166
NM_014721
PHACTR2

phosphatase and actin regulator 2

chr7_+_156716694 0.273


chr3_+_130014957 0.271 RAB7A
RAB7A, member RAS oncogene family
chr12_-_4358968 0.270 NM_020638
FGF23
fibroblast growth factor 23
chr5_+_140790510 0.270 PCDHGA12
protocadherin gamma subfamily A, 12
chr3_-_124893875 0.269 MYLK
myosin light chain kinase
chr4_+_114433551 0.268 ANK2
ankyrin 2, neuronal
chr1_+_180836050 0.265


chr13_-_31784088 0.263 NM_001136571
ZAR1L
zygote arrest 1-like
chr3_-_120861959 0.262 NM_022135
POPDC2
popeye domain containing 2
chr12_-_51457371 0.261 NM_015848
KRT76
keratin 76
chr12_-_52281050 0.261 NM_001130059
ATF7
activating transcription factor 7
chr5_+_125786717 0.260 NM_001146320
NM_001146321
NM_023927
GRAMD3


GRAM domain containing 3


chr8_-_7275061 0.260 NM_018661
DEFB103B
defensin, beta 103B
chr4_+_110968594 0.259 NM_006583
RRH
retinal pigment epithelium-derived rhodopsin homolog
chr10_+_49279647 0.259 NM_002750
NM_139046
NM_139047
NM_139049
MAPK8



mitogen-activated protein kinase 8



chr10_-_74384569 0.255 PLA2G12B
phospholipase A2, group XIIB
chr1_+_196874759 0.250 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr13_-_98708549 0.249 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr2_+_170742900 0.249 NM_001083615
NM_001171642
NM_138995
MYO3B


myosin IIIB


chr13_+_112825113 0.247 NM_000504
F10
coagulation factor X
chr5_-_132228375 0.246 NM_005260
GDF9
growth differentiation factor 9
chr7_-_107667728 0.246 NM_001037132
NRCAM
neuronal cell adhesion molecule
chr7_+_63411813 0.241 ZNF736
zinc finger protein 736
chr12_+_52105131 0.239 AMHR2
anti-Mullerian hormone receptor, type II
chr12_+_25096755 0.239 LRMP
lymphoid-restricted membrane protein
chr2_+_171280182 0.239


chr1_-_20178680 0.239 NM_001161729
PLA2G2A
phospholipase A2, group IIA (platelets, synovial fluid)
chr8_-_67253234 0.237 NM_000756
CRH
corticotropin releasing hormone
chr7_+_147918589 0.235 NM_145304
C7orf33
chromosome 7 open reading frame 33
chr5_+_140790365 0.232 PCDHGA12
protocadherin gamma subfamily A, 12
chr2_+_108604111 0.230 NM_001193484
LIMS1
LIM and senescent cell antigen-like domains 1
chr13_-_83354474 0.229 NM_052910
SLITRK1
SLIT and NTRK-like family, member 1
chr10_+_82163568 0.227 C10orf58
chromosome 10 open reading frame 58
chr14_-_79748273 0.226 NM_000793
NM_013989
DIO2

deiodinase, iodothyronine, type II

chr1_-_201321711 0.226 MYOG
myogenin (myogenic factor 4)
chr7_+_94135384 0.224 PEG10
paternally expressed 10
chr4_-_15686838 0.223 NM_001145849
NM_001145850
NM_001145851
NM_001145852
NM_006017
PROM1




prominin 1




chr2_-_55090759 0.223 NM_007008
RTN4
reticulon 4
chr6_+_167624792 0.223 NM_001143947
NM_018974
UNC93A

unc-93 homolog A (C. elegans)

chr17_-_46479127 0.222 SPAG9
sperm associated antigen 9
chr14_+_77939845 0.222 NM_004796
NRXN3
neurexin 3
chr3_-_124822113 0.221 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr17_-_36456949 0.221 NM_001123387
KRTAP2-1
keratin associated protein 2-1
chr6_-_31215089 0.219 NM_014069
PSORS1C2
psoriasis susceptibility 1 candidate 2
chr2_+_161981046 0.218 TBR1
T-box, brain, 1
chr2_-_37228452 0.217 NM_001135652
EIF2AK2
eukaryotic translation initiation factor 2-alpha kinase 2
chr12_+_108061584 0.217 NM_001093
ACACB
acetyl-CoA carboxylase beta
chr5_-_24535386 0.217 NM_001190450
CDH10
cadherin 10, type 2 (T2-cadherin)
chr17_+_4795128 0.216 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr5_+_156628929 0.215 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr3_+_46594079 0.214 NM_003212
TDGF1
teratocarcinoma-derived growth factor 1
chr1_+_165564904 0.213 NM_001198783
POU2F1
POU class 2 homeobox 1
chr11_+_123986661 0.213 NM_052959
PANX3
pannexin 3
chr3_+_16191159 0.212 NM_054110
GALNTL2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 2
chr11_+_4427100 0.209 NM_001005172
OR52K2
olfactory receptor, family 52, subfamily K, member 2
chr3_-_180467483 0.208 NM_001163677
NM_171828
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr1_+_151456683 0.208 NM_001195571
PRR9
proline rich 9
chr8_+_26569709 0.207 DPYSL2
dihydropyrimidinase-like 2
chr6_+_155579788 0.205 NM_001010927
TIAM2
T-cell lymphoma invasion and metastasis 2
chr11_+_65740789 0.203 PACS1
phosphofurin acidic cluster sorting protein 1
chr14_-_104330982 0.202 NM_005163
AKT1
v-akt murine thymoma viral oncogene homolog 1
chr17_-_36209672 0.201 NM_181535
KRT28
keratin 28
chr7_-_99555399 0.201 NM_001190415
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr6_-_114490701 0.201 NM_153612
HS3ST5
heparan sulfate (glucosamine) 3-O-sulfotransferase 5
chr3_+_157877146 0.200 NM_001184718
TIPARP
TCDD-inducible poly(ADP-ribose) polymerase
chr12_+_50981915 0.200 NM_002284
KRT86
keratin 86
chrX_+_134482212 0.198 NM_182540
DDX26B
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr3_+_153074118 0.197 NM_033050
SUCNR1
succinate receptor 1
chr12_+_50342814 0.197 NM_001177984
SCN8A
sodium channel, voltage gated, type VIII, alpha subunit
chr16_+_28797309 0.197 NM_004320
NM_173201
ATP2A1

ATPase, Ca++ transporting, cardiac muscle, fast twitch 1

chr10_+_35524835 0.195 NM_182721
NM_182722
NM_182723
NM_182724
NM_182725
CREM




cAMP responsive element modulator




chr1_+_242283129 0.195 NM_006352
ZNF238
zinc finger protein 238
chr3_-_42892636 0.194 NM_004391
CYP8B1
cytochrome P450, family 8, subfamily B, polypeptide 1
chrX_+_71280758 0.193 NM_207422
FLJ44635
TPT1-like protein
chr17_-_9870292 0.192 NM_001130831
GAS7
growth arrest-specific 7
chr5_+_137701122 0.192 NM_001135647
FAM53C
family with sequence similarity 53, member C
chr5_-_43326922 0.191 HMGCS1
3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
chr17_-_36475652 0.191 NM_033184
KRTAP2-4
keratin associated protein 2-4
chr5_+_140790310 0.189 NM_003735
NM_032094
PCDHGA12

protocadherin gamma subfamily A, 12

chr4_-_153523113 0.189 NM_001013415
FBXW7
F-box and WD repeat domain containing 7
chr8_+_32905027 0.189


chr17_-_78391178 0.188 NM_024702
ZNF750
zinc finger protein 750
chr22_-_39189369 0.188 MKL1
megakaryoblastic leukemia (translocation) 1
chr17_-_1195096 0.188 PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr3_+_138132006 0.187 NM_001190796
NCK1
NCK adaptor protein 1
chr5_+_140460240 0.187 NM_018937
PCDHB3
protocadherin beta 3
chr3_+_154362726 0.187 RAP2B
RAP2B, member of RAS oncogene family
chr17_+_38306339 0.186 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr6_-_87861492 0.186 NM_000735
CGA
glycoprotein hormones, alpha polypeptide
chr1_-_203579932 0.186 KLHDC8A
kelch domain containing 8A
chr4_+_71418886 0.185 NM_212557
AMTN
amelotin
chr18_+_30812205 0.185 NM_001143827
MAPRE2
microtubule-associated protein, RP/EB family, member 2
chr16_-_29817841 0.184 NM_001114099
NM_001114100
NM_012410
NM_201575
SEZ6L2



seizure related 6 homolog (mouse)-like 2



chr7_-_115458010 0.184 NM_001018058
NM_012252
TFEC

transcription factor EC

chr19_+_9064854 0.183 NM_001004456
OR1M1
olfactory receptor, family 1, subfamily M, member 1
chr5_-_35974493 0.182 NM_001042625
NM_144647
CAPSL

calcyphosine-like

chr19_+_49147219 0.182 NM_013359
ZNF221
zinc finger protein 221
chr14_+_34583863 0.181 NM_001079519
FAM177A1
family with sequence similarity 177, member A1
chr5_-_149446182 0.180 CSF1R
colony stimulating factor 1 receptor
chr9_+_135491305 0.176 NM_000787
DBH
dopamine beta-hydroxylase (dopamine beta-monooxygenase)
chr13_+_48923688 0.174 NM_001160308
SETDB2
SET domain, bifurcated 2
chr11_-_70350509 0.173 SHANK2
SH3 and multiple ankyrin repeat domains 2
chr2_-_165133239 0.172 GRB14
growth factor receptor-bound protein 14
chr4_-_176971175 0.169 NM_201591
GPM6A
glycoprotein M6A
chr15_-_70385709 0.169 NM_001172685
CELF6
CUGBP, Elav-like family member 6
chr3_-_184756101 0.168 NM_130446
KLHL6
kelch-like 6 (Drosophila)
chr11_-_110755112 0.168 POU2AF1
POU class 2 associating factor 1
chr6_-_33268177 0.167 NM_001163771
NM_080679
NM_080680
NM_080681
COL11A2



collagen, type XI, alpha 2



chr2_-_27967458 0.167 LOC100302650
hypothetical LOC100302650

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.