Motif ID: XBP1.p3

Z-value: 1.165


Transcription factors associated with XBP1.p3:

Gene SymbolEntrez IDGene Name
XBP1 7494 X-box binding protein 1



Activity profile for motif XBP1.p3.

activity profile for motif XBP1.p3


Sorted Z-values histogram for motif XBP1.p3

Sorted Z-values for motif XBP1.p3



Network of associatons between targets according to the STRING database.



First level regulatory network of XBP1.p3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_26631359 1.501 NM_024887
NM_205861
DHDDS

dehydrodolichyl diphosphate synthase

chr14_-_91576037 1.486 NM_004239
TRIP11
thyroid hormone receptor interactor 11
chr10_+_89409332 1.427 NM_001015880
NM_004670
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr2_+_183289205 1.396 NM_018981
DNAJC10
DnaJ (Hsp40) homolog, subfamily C, member 10
chr20_+_43478120 1.362 NM_001184728
NM_001184729
NM_001184730
NM_015937
PIGT



phosphatidylinositol glycan anchor biosynthesis, class T



chr6_+_144649142 1.352 UTRN
utrophin
chr15_-_72952648 1.283 NM_005697
SCAMP2
secretory carrier membrane protein 2
chr2_+_96790298 1.282 NM_020184
CNNM4
cyclin M4
chr14_-_38642029 1.247 SEC23A
Sec23 homolog A (S. cerevisiae)
chr14_+_30161267 1.232 NM_016106
NM_182835
SCFD1

sec1 family domain containing 1

chr2_+_171494026 1.224 GORASP2
golgi reassembly stacking protein 2, 55kDa
chr14_-_38642165 1.172 NM_006364
SEC23A
Sec23 homolog A (S. cerevisiae)
chr3_-_120665113 1.124 NM_018266
TMEM39A
transmembrane protein 39A
chr22_+_37193961 1.091 NM_006855
NM_016657
KDELR3

KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3

chr2_-_88707978 1.079 NM_004836
EIF2AK3
eukaryotic translation initiation factor 2-alpha kinase 3
chr20_-_33144013 1.059 TRPC4AP
transient receptor potential cation channel, subfamily C, member 4 associated protein
chr20_-_44426407 1.055 NM_015945
NM_173073
NM_173179
SLC35C2


solute carrier family 35, member C2


chr11_+_17254854 1.031 NM_005013
NUCB2
nucleobindin 2
chr1_-_143750988 1.020 NM_001198832
PDE4DIP
phosphodiesterase 4D interacting protein
chr2_-_33677798 1.019 NM_015475
FAM98A
family with sequence similarity 98, member A
chr2_-_69467825 0.966 NM_002056
GFPT1
glutamine--fructose-6-phosphate transaminase 1
chr5_+_112224875 0.962 NM_003135
SRP19
signal recognition particle 19kDa
chr14_+_38806280 0.956 CTAGE5
CTAGE family, member 5
chr2_+_84986273 0.932 NM_021103
TMSB10
thymosin beta 10
chr4_-_47611255 0.913 NM_152995
NFXL1
nuclear transcription factor, X-box binding-like 1
chr19_+_37874529 0.866 NM_001105570
NUDT19
nudix (nucleoside diphosphate linked moiety X)-type motif 19
chr20_+_25176698 0.842 NM_002862
PYGB
phosphorylase, glycogen; brain
chr12_+_55148567 0.815 NM_207344
SPRYD4
SPRY domain containing 4
chr5_-_108773468 0.814 NM_014819
PJA2
praja ring finger 2
chr12_-_28014151 0.807 NM_198964
NM_198966
PTHLH

parathyroid hormone-like hormone

chr20_-_33144262 0.786 NM_015638
NM_199368
TRPC4AP

transient receptor potential cation channel, subfamily C, member 4 associated protein

chr20_-_33144254 0.775 TRPC4AP
transient receptor potential cation channel, subfamily C, member 4 associated protein
chr2_-_20115269 0.764 NM_014713
LAPTM4A
lysosomal protein transmembrane 4 alpha
chr16_-_30477006 0.757 NM_001172679
NM_033410
ZNF764

zinc finger protein 764

chr6_+_41714171 0.746 NM_005586
MDFI
MyoD family inhibitor
chr3_-_57557906 0.745 ARF4
ADP-ribosylation factor 4
chr20_+_32414715 0.741 NM_031483
ITCH
itchy E3 ubiquitin protein ligase homolog (mouse)
chr16_-_11798507 0.725 ZC3H7A
zinc finger CCCH-type containing 7A
chr1_-_143643324 0.713 NM_001002811
PDE4DIP
phosphodiesterase 4D interacting protein
chr14_+_38806028 0.709 NM_005930
NM_203355
CTAGE5

CTAGE family, member 5

chr2_+_171493870 0.695 NM_015530
GORASP2
golgi reassembly stacking protein 2, 55kDa
chr3_+_124268545 0.687 NM_006810
PDIA5
protein disulfide isomerase family A, member 5
chr5_+_119827903 0.686 NM_016644
PRR16
proline rich 16
chr7_-_30032649 0.668 NM_017946
FKBP14
FK506 binding protein 14, 22 kDa
chr6_+_33276580 0.659 NM_001077516
NM_006979
SLC39A7

solute carrier family 39 (zinc transporter), member 7

chr11_+_65576379 0.656 NM_006842
SF3B2
splicing factor 3b, subunit 2, 145kDa
chr12_-_100325630 0.654 NM_001177
ARL1
ADP-ribosylation factor-like 1
chr7_-_5428043 0.651 TNRC18
trinucleotide repeat containing 18
chr11_-_102081654 0.640 NM_022122
MMP27
matrix metallopeptidase 27
chr4_-_119976631 0.635 SEC24D
SEC24 family, member D (S. cerevisiae)
chr6_+_97076390 0.617 NM_015323
KIAA0776
KIAA0776
chr3_-_107070400 0.606 NM_170662
CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr2_-_101134146 0.600 NM_001102426
TBC1D8
TBC1 domain family, member 8 (with GRAM domain)
chr3_+_173240983 0.596 NM_001135095
FNDC3B
fibronectin type III domain containing 3B
chr5_-_137116746 0.595 HNRNPA0
heterogeneous nuclear ribonucleoprotein A0
chr3_+_37259684 0.590 NM_001172713
NM_002078
GOLGA4

golgin A4

chr11_-_72986738 0.569 NM_015159
FAM168A
family with sequence similarity 168, member A
chr10_+_32775027 0.564 NM_001026383
NM_145023
CCDC7

coiled-coil domain containing 7

chr17_+_42355492 0.555 GOSR2
golgi SNAP receptor complex member 2
chr2_-_15618865 0.548 NBAS
neuroblastoma amplified sequence
chr14_-_22904074 0.540


chr6_+_97076451 0.536 KIAA0776
KIAA0776
chr14_-_22496098 0.529 NM_001166269
NM_001166270
NM_017815
HAUS4


HAUS augmin-like complex, subunit 4


chr6_-_33276416 0.527 RXRB
retinoid X receptor, beta
chr2_+_84986510 0.515 TMSB10
thymosin beta 10
chr6_-_33276426 0.511 RXRB
retinoid X receptor, beta
chr1_+_109434896 0.509 NM_020141
TMEM167B
transmembrane protein 167B
chr2_-_182229977 0.508 NM_001030311
NM_001030312
NM_001030313
NM_001160277
NM_201548
CERKL




ceramide kinase-like




chr2_-_15618896 0.505 NM_015909
NBAS
neuroblastoma amplified sequence
chr11_+_117948350 0.502 ARCN1
archain 1
chr2_-_20114761 0.491 LAPTM4A
lysosomal protein transmembrane 4 alpha
chr16_-_31427130 0.491 NM_022744
C16orf58
chromosome 16 open reading frame 58
chr14_+_30161285 0.490 SCFD1
sec1 family domain containing 1
chr9_-_112840064 0.487 NM_001401
NM_057159
LPAR1

lysophosphatidic acid receptor 1

chr3_-_122951200 0.483 NM_004487
GOLGB1
golgin B1
chr15_-_61680003 0.481 LOC100130855
hypothetical LOC100130855
chr2_+_241156776 0.479 NM_018226
RNPEPL1
arginyl aminopeptidase (aminopeptidase B)-like 1
chr9_-_111300350 0.471 NM_001145368
NM_002829
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr10_+_101409159 0.460 NM_020354
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr10_-_71600191 0.459 NM_001142648
NM_020150
SAR1A

SAR1 homolog A (S. cerevisiae)

chr3_-_188945921 0.454 BCL6
B-cell CLL/lymphoma 6
chr7_+_96584929 0.437 ACN9
ACN9 homolog (S. cerevisiae)
chr14_+_51526071 0.432 C14orf166
chromosome 14 open reading frame 166
chr7_-_127833231 0.423 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr16_-_30453499 0.418 ZNF747
zinc finger protein 747
chr14_+_51525942 0.415 NM_016039
C14orf166
chromosome 14 open reading frame 166
chr6_-_34772495 0.410 C6orf106
chromosome 6 open reading frame 106
chr6_-_109809595 0.410 CD164
CD164 molecule, sialomucin
chr2_+_27109341 0.408 TMEM214
transmembrane protein 214
chr5_-_157218555 0.407 NM_001195555
NM_001195556
NM_014666
CLINT1


clathrin interactor 1


chr6_-_86445138 0.404 SNHG5
small nucleolar RNA host gene 5 (non-protein coding)
chr14_+_49157150 0.398 NM_002408
MGAT2
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase
chr11_-_118477739 0.398 DPAGT1
dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr2_+_220116986 0.393 NM_001005209
TMEM198
transmembrane protein 198
chr2_-_154043403 0.392 NM_019845
RPRM
reprimo, TP53 dependent G2 arrest mediator candidate
chr3_-_73756668 0.389 NM_015009
PDZRN3
PDZ domain containing ring finger 3
chr2_+_220117009 0.378 TMEM198
transmembrane protein 198
chr2_-_99319197 0.376 NM_005783
TXNDC9
thioredoxin domain containing 9
chr14_-_23734598 0.375 NM_001014842
NM_006405
TM9SF1

transmembrane 9 superfamily member 1

chr15_-_49817454 0.375 NM_153374
LYSMD2
LysM, putative peptidoglycan-binding, domain containing 2
chr6_+_43036442 0.372 NM_018960
GNMT
glycine N-methyltransferase
chr2_+_241903395 0.367 NM_001008491
NM_006155
SEPT2

septin 2

chr2_-_20114881 0.366 LAPTM4A
lysosomal protein transmembrane 4 alpha
chr11_+_117948301 0.364 NM_001142281
NM_001655
ARCN1

archain 1

chr12_+_61146798 0.354 NM_015026
MON2
MON2 homolog (S. cerevisiae)
chr2_-_220116508 0.351 NM_024536
CHPF
chondroitin polymerizing factor
chr10_+_106103503 0.348 NM_001008723
CCDC147
coiled-coil domain containing 147
chr10_+_104667991 0.345 NM_017649
NM_199076
NM_199077
CNNM2


cyclin M2


chr5_+_126881207 0.342 NM_130809
PRRC1
proline-rich coiled-coil 1
chr13_+_24940965 0.341 ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr12_+_61147083 0.338 MON2
MON2 homolog (S. cerevisiae)
chr19_-_44214707 0.330


chr1_-_87152372 0.329 SEP15
15 kDa selenoprotein
chr6_+_27208763 0.328 NM_021064
HIST1H2AG
histone cluster 1, H2ag
chr4_-_119976736 0.328 NM_014822
SEC24D
SEC24 family, member D (S. cerevisiae)
chr6_-_33276347 0.326 NM_021976
RXRB
retinoid X receptor, beta
chr11_-_74819165 0.324 NM_001039548
KLHL35
kelch-like 35 (Drosophila)
chr6_-_34772565 0.324 NM_022758
NM_024294
C6orf106

chromosome 6 open reading frame 106

chr5_+_119827797 0.323 PRR16
proline rich 16
chr2_+_200528173 0.321 NM_024520
C2orf47
chromosome 2 open reading frame 47
chr10_-_22332368 0.317 DNAJC1
DnaJ (Hsp40) homolog, subfamily C, member 1
chr17_+_42355482 0.310 NM_001012511
NM_004287
NM_054022
GOSR2


golgi SNAP receptor complex member 2


chr9_-_129573330 0.302 NM_005489
SH2D3C
SH2 domain containing 3C
chr8_+_95722516 0.301 NM_001034915
NM_001122825
NM_001122826
NM_001122827
NM_017697
ESRP1




epithelial splicing regulatory protein 1




chr11_+_113776582 0.297 NM_016090
RBM7
RNA binding motif protein 7
chr16_+_51722285 0.294 CHD9
chromodomain helicase DNA binding protein 9
chr11_-_61441536 0.294 NM_013401
RAB3IL1
RAB3A interacting protein (rabin3)-like 1
chr2_+_203811903 0.294 CYP20A1
cytochrome P450, family 20, subfamily A, polypeptide 1
chr18_-_42956645 0.294 IER3IP1
immediate early response 3 interacting protein 1
chr17_-_37828643 0.292 NM_012232
PTRF
polymerase I and transcript release factor
chr12_+_67489063 0.289 MDM2
Mdm2 p53 binding protein homolog (mouse)
chr2_+_220116596 0.285 TMEM198
transmembrane protein 198
chr19_+_51796399 0.285 CALM3
calmodulin 3 (phosphorylase kinase, delta)
chr13_+_24940917 0.284 ATP8A2
ATPase, aminophospholipid transporter, class I, type 8A, member 2
chr6_-_7855277 0.280 TXNDC5
thioredoxin domain containing 5 (endoplasmic reticulum)
chr1_+_159390379 0.279 UFC1
ubiquitin-fold modifier conjugating enzyme 1
chr1_-_206484258 0.277 NM_025179
PLXNA2
plexin A2
chr2_-_27147995 0.277 NM_001134693
OST4
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr2_-_74915722 0.272


chr2_-_27195276 0.271 NM_001166239
CGREF1
cell growth regulator with EF-hand domain 1
chr17_+_3993690 0.271 CYB5D2
cytochrome b5 domain containing 2
chr1_-_87152396 0.270 SEP15
15 kDa selenoprotein
chr12_+_70519753 0.267 NM_001146213
NM_001146214
NM_022771
TBC1D15


TBC1 domain family, member 15


chr12_-_56445653 0.265 CYP27B1
cytochrome P450, family 27, subfamily B, polypeptide 1
chr3_-_57558120 0.260 ARF4
ADP-ribosylation factor 4
chr22_+_44828338 0.257


chr19_-_54636425 0.256 NM_020309
SLC17A7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr2_+_64604940 0.256 NM_001002243
NM_017657
NM_203437
AFTPH


aftiphilin


chr6_+_1336077 0.253


chr15_-_81744469 0.250 NM_001717
BNC1
basonuclin 1
chr14_+_49135164 0.250 NM_152329
NM_203467
LRR1

leucine rich repeat protein 1

chr12_+_58276114 0.246 SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr3_+_133861894 0.243 UBA5
ubiquitin-like modifier activating enzyme 5
chrX_+_152565849 0.242 DUSP9
dual specificity phosphatase 9
chr3_+_129253997 0.241 SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr18_-_42956733 0.237 NM_016097
IER3IP1
immediate early response 3 interacting protein 1
chr2_+_27109249 0.237 NM_001083590
NM_017727
TMEM214

transmembrane protein 214

chr17_+_52688842 0.236 NM_138962
MSI2
musashi homolog 2 (Drosophila)
chr5_-_121441805 0.234 LOX
lysyl oxidase
chr11_+_113776504 0.233 RBM7
RNA binding motif protein 7
chr6_-_108385905 0.232 SEC63
SEC63 homolog (S. cerevisiae)
chr3_-_134863316 0.230 NM_007027
TOPBP1
topoisomerase (DNA) II binding protein 1
chr3_+_129253977 0.226 SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr4_-_122063118 0.226 NM_018699
PRDM5
PR domain containing 5
chr22_-_29015452 0.225 NM_001037666
GATSL3
GATS protein-like 3
chr2_+_27740254 0.224 SLC4A1AP
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr2_+_64605049 0.222 AFTPH
aftiphilin
chr3_+_129254032 0.221


chr3_+_101462375 0.220 NM_018309
TBC1D23
TBC1 domain family, member 23
chr18_-_42956730 0.217 IER3IP1
immediate early response 3 interacting protein 1
chr4_-_39136448 0.217 NM_001024921
RPL9
ribosomal protein L9
chr2_+_75039273 0.211 NM_019896
POLE4
polymerase (DNA-directed), epsilon 4 (p12 subunit)
chr2_+_202607554 0.208 NM_003507
FZD7
frizzled homolog 7 (Drosophila)
chr3_+_129253816 0.207 NM_013336
SEC61A1
Sec61 alpha 1 subunit (S. cerevisiae)
chr2_-_71210856 0.207 NM_032601
MCEE
methylmalonyl CoA epimerase
chr3_+_171167243 0.205 NM_003262
SEC62
SEC62 homolog (S. cerevisiae)
chr1_+_234625338 0.203 NM_080738
EDARADD
EDAR-associated death domain
chr14_-_49157076 0.201 NM_001001
RPL36AL
ribosomal protein L36a-like
chr12_+_88268845 0.201 LOC100131490
hypothetical LOC100131490
chr9_+_91115924 0.198 NM_001827
CKS2
CDC28 protein kinase regulatory subunit 2
chr8_+_120289735 0.197 NM_052886
MAL2
mal, T-cell differentiation protein 2 (gene/pseudogene)
chr20_+_49008754 0.196 NM_014484
MOCS3
molybdenum cofactor synthesis 3
chr10_+_92970487 0.194 PCGF5
polycomb group ring finger 5
chr14_-_22904218 0.194 EFS
embryonal Fyn-associated substrate
chr17_+_14145051 0.193 NM_006041
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr1_-_21982037 0.192 USP48
ubiquitin specific peptidase 48
chr3_-_180651874 0.191 GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr11_+_124967961 0.191 STT3A
STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
chr11_+_61647990 0.188 NM_001040694
NM_020238
INCENP

inner centromere protein antigens 135/155kDa

chr20_+_61054539 0.187 SLC17A9
solute carrier family 17, member 9
chr14_+_38805622 0.184 CTAGE5
CTAGE family, member 5
chr2_+_27109327 0.184 TMEM214
transmembrane protein 214
chr11_-_65813031 0.184 YIF1A
Yip1 interacting factor homolog A (S. cerevisiae)
chr20_-_33198721 0.184 NM_001145025
NM_018217
EDEM2

ER degradation enhancer, mannosidase alpha-like 2

chr17_+_61729193 0.181 PRKCA
protein kinase C, alpha
chr13_+_44813479 0.180 LOC100190939
hypothetical LOC100190939
chr19_+_4423149 0.179 NM_001001520
NM_032631
HDGFRP2

hepatoma-derived growth factor-related protein 2

chr14_-_22904239 0.179 EFS
embryonal Fyn-associated substrate
chr16_+_71256497 0.178


chr17_+_26839143 0.178 RAB11FIP4
RAB11 family interacting protein 4 (class II)

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
358.47 4.59e-04 GO:0005797 Golgi medial cisterna
6.81 1.18e-03 GO:0005794 Golgi apparatus
8.22 1.82e-03 GO:0042175 nuclear membrane-endoplasmic reticulum network
6.15 2.28e-03 GO:0005783 endoplasmic reticulum
35.42 2.92e-03 GO:0031985 Golgi cisterna
4.87 2.99e-03 GO:0012505 endomembrane system
7.50 3.05e-03 GO:0044432 endoplasmic reticulum part
34.52 3.15e-03 GO:0031984 organelle subcompartment
26.41 7.00e-03 GO:0005795 Golgi stack
8.10 9.83e-03 GO:0044431 Golgi apparatus part
7.02 1.91e-02 GO:0005789 endoplasmic reticulum membrane
3.65 2.32e-02 GO:0031090 organelle membrane

Nothing significant found in function category.