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• Mean activities

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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: CEBPA,B_DDIT3.p2

Z-value: 0.928

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr3_+_186330844	5.241	NM_001622	AHSG	alpha-2-HS-glycoprotein
chr3_+_186330859	5.223		AHSG	alpha-2-HS-glycoprotein
chr3_+_186330711	4.508		AHSG	alpha-2-HS-glycoprotein
chr17_-_39092714	3.578		KRT23	keratin 23 (histone deacetylase inducible)
chr17_-_64225496	3.364	NM_000042	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr6_+_31895201	2.520	NM_000063 NM_001145903	C2	complement component 2
chr19_+_45452427	2.500		APOC2	apolipoprotein C-II
chr10_-_116444112	2.473		ABLIM1	actin binding LIM protein 1
chr6_+_31895401	2.377		C2	complement component 2
chr10_-_116444374	2.322	NM_001003407 NM_001003408	ABLIM1	actin binding LIM protein 1
chr9_+_117092068	2.152	NM_000608	ORM2	orosomucoid 2
chr9_+_117085302	2.002	NM_000607	ORM1	orosomucoid 1
chr4_-_10023094	1.966	NM_020041	SLC2A9	solute carrier family 2 (facilitated glucose transporter), member 9
chr12_-_122296619	1.862	NM_002150	HPD	4-hydroxyphenylpyruvate dioxygenase
chr9_-_123812535	1.859	NM_001735	C5	complement component 5
chr2_-_216300770	1.810	NM_002026 NM_054034 NM_212474 NM_212476 NM_212478 NM_212482	FN1	fibronectin 1
chr8_-_17743062	1.679		FGL1	fibrinogen-like 1
chrX_-_105282714	1.617	NM_000354	SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr3_-_79817058	1.432	NM_002941	ROBO1	roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr1_+_150954498	1.331	NM_003568	ANXA9	annexin A9
chr6_+_167704802	1.321	NM_001143947 NM_018974	UNC93A	unc-93 homolog A (C. elegans)
chr12_-_63328857	1.271		PPM1H	protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr12_-_52845862	1.166	NM_005555	KRT6B	keratin 6B
chr2_+_128175989	1.052	NM_000312	PROC	protein C (inactivator of coagulation factors Va and VIIIa)
chr17_+_1665281	1.031		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr3_-_148939784	1.012	NM_000096	CP	ceruloplasmin (ferroxidase)
chrX_-_13835187	0.933		GPM6B	glycoprotein M6B
chr19_+_11350282	0.903	NM_018687	C19orf80	chromosome 19 open reading frame 80
chr17_+_1665306	0.901		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr3_+_12392993	0.891	NM_015869	PPARG	peroxisome proliferator-activated receptor gamma
chr17_+_1665342	0.813		SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr19_+_33864574	0.803	NM_001806	CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma
chr11_-_8739398	0.778		ST5	suppression of tumorigenicity 5
chr16_-_28550227	0.773		NUPR1	nuclear protein, transcriptional regulator, 1
chr2_-_63815581	0.737		WDPCP	WD repeat containing planar cell polarity effector
chr16_-_28550324	0.721	NM_001042483 NM_012385	NUPR1	nuclear protein, transcriptional regulator, 1
chr17_+_1665233	0.691	NM_002615	SERPINF1	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr16_+_56966025	0.687		HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr6_+_31913852	0.686		CFB	complement factor B
chr3_-_49726081	0.679	NM_020998	MST1	macrophage stimulating 1 (hepatocyte growth factor-like)
chr10_-_92681025	0.677	NM_014391	ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr10_-_22498911	0.666	NM_001199938	EBLN1	endogenous Bornavirus-like nucleoprotein 1
chr6_+_131894343	0.654	NM_000045 NM_001244438	ARG1	arginase, liver
chr2_+_11674241	0.643	NM_014668	GREB1	growth regulation by estrogen in breast cancer 1
chr3_-_129599220	0.639	NM_001017395	TMCC1	transmembrane and coiled-coil domain family 1
chrX_-_131573638	0.600	NM_018388 NM_133486	MBNL3	muscleblind-like 3 (Drosophila)
chrX_-_15288588	0.596	NM_001168531	ASB9	ankyrin repeat and SOCS box containing 9
chr9_+_80911990	0.583	NM_021154 NM_058179	PSAT1	phosphoserine aminotransferase 1
chr5_-_147211141	0.583		SPINK1	serine peptidase inhibitor, Kazal type 1
chr12_+_100867739	0.573		NR1H4	nuclear receptor subfamily 1, group H, member 4
chr17_-_56492938	0.542		RNF43	ring finger protein 43
chr17_+_4675175	0.531	NM_003963	TM4SF5	transmembrane 4 L six family member 5
chr4_+_187187342	0.499		F11	coagulation factor XI
chr11_+_22689653	0.474	NM_177553	GAS2	growth arrest-specific 2
chr10_-_92680784	0.473		ANKRD1	ankyrin repeat domain 1 (cardiac muscle)
chr2_+_234296799	0.471	NM_003648	DGKD	diacylglycerol kinase, delta 130kDa
chr18_-_55288951	0.462		NARS	asparaginyl-tRNA synthetase
chrX_-_13835213	0.457		GPM6B	glycoprotein M6B
chrY_+_2709630	0.448		RPS4Y1	ribosomal protein S4, Y-linked 1
chr18_-_55289014	0.444		NARS	asparaginyl-tRNA synthetase
chrX_+_114827818	0.442	NM_001136025 NM_001172335	PLS3	plastin 3
chr4_+_184020343	0.437	NM_024949	WWC2	WW and C2 domain containing 2
chr17_-_55980749	0.435	NM_017949	CUEDC1	CUE domain containing 1
chr15_+_82944772	0.422		AGSK1	golgin subfamily A member 2-like
chr5_-_16738346	0.418		MYO10	myosin X
chr15_+_82944821	0.387		AGSK1	golgin subfamily A member 2-like
chr5_-_140013285	0.385	NM_001040021 NM_001174104 NM_001174105	CD14	CD14 molecule
chr1_-_67519698	0.384		SLC35D1	solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chrX_-_40506800	0.369	NM_144970	CXorf38	chromosome X open reading frame 38
chr1_-_173886401	0.368		SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1
chrX_-_40506666	0.365		CXorf38	chromosome X open reading frame 38
chr19_+_33865429	0.348	NM_001252296	CEBPG	CCAAT/enhancer binding protein (C/EBP), gamma
chr6_+_36644236	0.347	NM_001220777 NM_078467	CDKN1A	cyclin-dependent kinase inhibitor 1A (p21, Cip1)
chr18_-_55289026	0.344	NM_004539	NARS	asparaginyl-tRNA synthetase
chr8_+_123793988	0.340		ZHX2	zinc fingers and homeoboxes 2
chr6_+_132129195	0.339		ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr12_-_57009361	0.338		BAZ2A	bromodomain adjacent to zinc finger domain, 2A
chr15_+_58724174	0.332	NM_000236	LIPC	lipase, hepatic
chr4_+_187187117	0.324	NM_000128	F11	coagulation factor XI
chr8_-_12973752	0.323	NM_001164271	DLC1	deleted in liver cancer 1
chr8_-_110657745	0.314	NM_001099751 NM_001099752	SYBU	syntabulin (syntaxin-interacting)
chr15_+_85923739	0.312	NM_006738 NM_007200	AKAP13	A kinase (PRKA) anchor protein 13
chr16_-_70323407	0.304	NM_001605	AARS	alanyl-tRNA synthetase
chr11_-_66675334	0.297	NM_022172	PC	pyruvate carboxylase
chrX_+_46940235	0.294		RGN	regucalcin (senescence marker protein-30)
chr12_+_100897137	0.287	NM_001206992 NM_001206993	NR1H4	nuclear receptor subfamily 1, group H, member 4
chr16_-_90076528	0.282	NM_024043	DBNDD1	dysbindin (dystrobrevin binding protein 1) domain containing 1
chr4_-_15940362	0.282	NM_005130	FGFBP1	fibroblast growth factor binding protein 1
chr3_+_57994087	0.282	NM_001164317 NM_001164318 NM_001164319 NM_001457	FLNB	filamin B, beta
chr6_+_31913920	0.276		CFB	complement factor B
chr16_-_70323343	0.275		AARS	alanyl-tRNA synthetase
chr2_-_113594325	0.269	NM_000576	IL1B	interleukin 1, beta
chr2_-_110371669	0.269	NM_144710 NM_178584	SEPT10	septin 10
chrX_-_13835012	0.260		GPM6B	glycoprotein M6B
chr1_+_151630710	0.259		SNX27	sorting nexin family member 27
chr17_-_42200957	0.252		HDAC5	histone deacetylase 5
chr19_-_47735858	0.251	NM_001127240 NM_001127241 NM_001127242	BBC3	BCL2 binding component 3
chr6_-_29527477	0.251		UBD	ubiquitin D
chr15_-_77176191	0.247	NM_020843	SCAPER	S-phase cyclin A-associated protein in the ER
chr5_+_75699003	0.240	NM_006633	IQGAP2	IQ motif containing GTPase activating protein 2
chr15_-_34212523	0.239
chr6_+_64356430	0.236	NM_015153	PHF3	PHD finger protein 3
chr10_-_79789290	0.234	NM_007055	POLR3A	polymerase (RNA) III (DNA directed) polypeptide A, 155kDa
chr7_+_26400503	0.232	NM_001199837	SNX10	sorting nexin 10
chrX_-_15288172	0.229	NM_001031739 NM_001168530 NM_024087	ASB9	ankyrin repeat and SOCS box containing 9
chr14_-_21572789	0.229	NM_001102454	ZNF219	zinc finger protein 219
chr8_+_124194751	0.227	NM_032899 NM_207006	FAM83A	family with sequence similarity 83, member A
chr14_-_68162419	0.224	NM_001252650 NM_016026	RDH11	retinol dehydrogenase 11 (all-trans/9-cis/11-cis)
chr5_-_16742336	0.223		MYO10	myosin X
chr8_-_110661007	0.220	NM_001099747 NM_001099748 NM_001099749 NM_001099750 NM_017786	SYBU	syntabulin (syntaxin-interacting)
chr16_+_66995099	0.218	NM_001185177 NM_024922	CES3	carboxylesterase 3
chr3_+_9476506	0.216
chr12_-_52867521	0.215	NM_173086	KRT6C	keratin 6C
chr9_-_130712866	0.209	NM_203305	FAM102A	family with sequence similarity 102, member A
chr19_+_50015535	0.204	NM_001136019	FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chr1_+_24834083	0.201	NM_001251978	RCAN3	RCAN family member 3
chr6_-_11779279	0.200	NM_001143948 NM_032744	C6orf105	chromosome 6 open reading frame 105
chr20_+_361675	0.198		TRIB3	tribbles homolog 3 (Drosophila)
chr10_+_63808968	0.196	NM_001244638	ARID5B	AT rich interactive domain 5B (MRF1-like)
chrX_-_13062720	0.192	NM_174901	FAM9C	family with sequence similarity 9, member C
chr8_-_66701175	0.181	NM_002603	PDE7A	phosphodiesterase 7A
chr1_+_26503973	0.179	NM_006314	CNKSR1	connector enhancer of kinase suppressor of Ras 1
chr14_-_70883680	0.176	NM_001202547 NM_001202548 NM_001202549 NM_018373	SYNJ2BP-COX16 SYNJ2BP	SYNJ2BP-COX16 readthrough synaptojanin 2 binding protein
chr13_-_30169584	0.174		SLC7A1	solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr1_-_67520028	0.172	NM_015139	SLC35D1	solute carrier family 35 (UDP-glucuronic acid/UDP-N-acetylgalactosamine dual transporter), member D1
chrX_-_13835313	0.169	NM_001001995 NM_001001996 NM_005278	GPM6B	glycoprotein M6B
chr8_-_28347733	0.165	NM_172366	FBXO16 ZNF395	F-box protein 16 zinc finger protein 395
chr17_-_42201009	0.161	NM_001015053 NM_005474	HDAC5	histone deacetylase 5
chr1_+_212782103	0.155		ATF3	activating transcription factor 3
chr3_+_185080835	0.152	NM_004721	MAP3K13	mitogen-activated protein kinase kinase kinase 13
chr14_+_35514112	0.151	NM_001079519	FAM177A1	family with sequence similarity 177, member A1
chr3_+_186435097	0.151	NM_000893 NM_001102416 NM_001166451	KNG1	kininogen 1
chr1_+_17906941	0.150	NM_001011722	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like
chr11_+_73661363	0.149	NM_153614	DNAJB13	DnaJ (Hsp40) homolog, subfamily B, member 13
chr15_-_73051650	0.148
chr5_+_125758818	0.147	NM_001146320 NM_001146321 NM_023927	GRAMD3	GRAM domain containing 3
chr19_+_5823817	0.145	NM_004558	NRTN	neurturin
chr14_-_95608054	0.144	NM_030621	DICER1	dicer 1, ribonuclease type III
chr3_+_186739643	0.143	NM_003032	ST6GAL1	ST6 beta-galactosamide alpha-2,6-sialyltranferase 1
chr16_+_3405888	0.143	NM_012368	OR2C1	olfactory receptor, family 2, subfamily C, member 1
chr13_-_99174251	0.143	NM_003576	STK24	serine/threonine kinase 24
chr2_+_237993954	0.139	NM_006710 NM_198189	COPS8	COP9 constitutive photomorphogenic homolog subunit 8 (Arabidopsis)
chr7_-_91763677	0.139		CYP51A1	cytochrome P450, family 51, subfamily A, polypeptide 1
chrX_-_108976509	0.132	NM_004458 NM_022977	ACSL4	acyl-CoA synthetase long-chain family member 4
chr17_-_7578810	0.129	NM_001126115 NM_001126116 NM_001126117	TP53	tumor protein p53
chr20_+_11898536	0.128	NM_014962	BTBD3	BTB (POZ) domain containing 3
chr10_-_29923900	0.127	NM_021738	SVIL	supervillin
chr18_-_61311465	0.124	NM_002974	SERPINB4	serpin peptidase inhibitor, clade B (ovalbumin), member 4
chr1_-_21437875	0.124	NM_003760	EIF4G3	eukaryotic translation initiation factor 4 gamma, 3
chr12_-_71551564	0.123		TSPAN8	tetraspanin 8
chr6_-_134498973	0.123	NM_001143677	SGK1	serum/glucocorticoid regulated kinase 1
chr16_+_24266873	0.122	NM_006539	CACNG3	calcium channel, voltage-dependent, gamma subunit 3
chr19_+_47813074	0.121	NM_001736	C5AR1	complement component 5a receptor 1
chr17_-_39768939	0.119	NM_005557	KRT16	keratin 16
chr5_-_140013034	0.119	NM_000591	CD14	CD14 molecule
chr2_-_74542149	0.116	NM_021196	SLC4A5	solute carrier family 4, sodium bicarbonate cotransporter, member 5
chr11_-_8832881	0.111	NM_139157	ST5	suppression of tumorigenicity 5
chr10_-_47173917	0.111	NM_001040084 NM_001098845	ANXA8L2 ANXA8 ANXA8L1	annexin A8-like 2 annexin A8 annexin A8-like 1
chr20_+_32150139	0.109	NM_001039709 NM_005093	CBFA2T2	core-binding factor, runt domain, alpha subunit 2; translocated to, 2
chr6_+_35310399	0.109		PPARD	peroxisome proliferator-activated receptor delta
chr14_-_95599794	0.108	NM_001195573	DICER1	dicer 1, ribonuclease type III
chr1_+_212781969	0.107	NM_001040619 NM_001206484 NM_001206488 NM_001674	ATF3	activating transcription factor 3
chr2_-_211018294	0.106		C2orf67	chromosome 2 open reading frame 67
chr22_+_38004676	0.105		GGA1	golgi-associated, gamma adaptin ear containing, ARF binding protein 1
chr14_+_29241989	0.103		C14orf23	chromosome 14 open reading frame 23
chr1_-_151826042	0.103	NM_182578	THEM5	thioesterase superfamily member 5
chr12_-_10151689	0.101	NM_001099431 NM_016509	CLEC1B	C-type lectin domain family 1, member B
chr11_+_18287807	0.101	NM_000331 NM_001178006 NM_199161	SAA1	serum amyloid A1
chr1_+_236681513	0.101	NM_201545	LGALS8	lectin, galactoside-binding, soluble, 8
chr15_-_51386815	0.099		TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr17_+_56315786	0.098	NM_001160102 NM_006151	LPO	lactoperoxidase
chr5_-_24645084	0.097	NM_006727	CDH10	cadherin 10, type 2 (T2-cadherin)
chr17_+_61851557	0.096	NM_007372 NM_203499	DDX42	DEAD (Asp-Glu-Ala-Asp) box polypeptide 42
chr9_+_135937364	0.095	NM_001807	CEL	carboxyl ester lipase (bile salt-stimulated lipase)
chr7_-_91763828	0.094	NM_000786	CYP51A1	cytochrome P450, family 51, subfamily A, polypeptide 1
chr3_+_49568370	0.093		DAG1	dystroglycan 1 (dystrophin-associated glycoprotein 1)
chr2_+_236402948	0.092		AGAP1	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr13_-_45914246	0.091		TPT1	tumor protein, translationally-controlled 1
chr12_-_8043743	0.090		SLC2A14	solute carrier family 2 (facilitated glucose transporter), member 14
chr5_-_77844975	0.088		LHFPL2	lipoma HMGIC fusion partner-like 2
chr7_+_129847699	0.088	NM_145268	C7orf45	chromosome 7 open reading frame 45
chr4_+_111397181	0.088	NM_001977	ENPEP	glutamyl aminopeptidase (aminopeptidase A)
chr19_+_48758931	0.088		LOC100505812	uncharacterized LOC100505812
chr7_-_91764036	0.087	NM_001146152	CYP51A1	cytochrome P450, family 51, subfamily A, polypeptide 1
chr2_+_135011829	0.084	NM_002410	MGAT5	mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr15_+_89182038	0.081	NM_002201	ISG20	interferon stimulated exonuclease gene 20kDa
chr21_-_43816123	0.081	NM_024022 NM_032405	TMPRSS3	transmembrane protease, serine 3
chr1_+_161185061	0.080		FCER1G	Fc fragment of IgE, high affinity I, receptor for; gamma polypeptide
chr6_+_167525294	0.079	NM_004367	CCR6	chemokine (C-C motif) receptor 6
chrX_-_13956644	0.078	NM_001001994	GPM6B	glycoprotein M6B
chr3_+_171757442	0.078		FNDC3B	fibronectin type III domain containing 3B
chr22_-_43355886	0.077	NM_001184971	PACSIN2	protein kinase C and casein kinase substrate in neurons 2
chr6_-_30043547	0.074	NM_170769 NM_025236	RNF39	ring finger protein 39
chr18_-_3011944	0.074	NM_014646	LPIN2	lipin 2
chr6_+_28493788	0.073	NM_001509 NM_003996	GPX5	glutathione peroxidase 5 (epididymal androgen-related protein)
chr6_+_43399488	0.072	NM_033450	ABCC10	ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr19_-_47128293	0.072	NM_000960	PTGIR	prostaglandin I2 (prostacyclin) receptor (IP)
chr3_-_47957475	0.071
chr5_+_125759076	0.070		GRAMD3	GRAM domain containing 3
chr19_+_17516502	0.070		LOC100507535	uncharacterized LOC100507535

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
62.89	8.73e-05	GO:0006953	acute-phase response
15.76	2.97e-04	GO:0032101	regulation of response to external stimulus
42.34	4.42e-04	GO:0002526	acute inflammatory response
183.35	1.07e-02	GO:0051006	positive regulation of lipoprotein lipase activity
11.27	1.33e-02	GO:0006954	inflammatory response
30.59	2.67e-02	GO:0050680	negative regulation of epithelial cell proliferation
27.54	3.66e-02	GO:0072376	protein activation cascade
25.42	4.64e-02	GO:0032102	negative regulation of response to external stimulus

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
10.79	3.84e-10	GO:0005615	extracellular space
8.58	6.94e-09	GO:0044421	extracellular region part
5.06	4.80e-06	GO:0005576	extracellular region
157.16	3.19e-03	GO:0005577	fibrinogen complex
100.03	8.31e-03	GO:0042627	chylomicron
61.14	2.29e-02	GO:0034361	very-low-density lipoprotein particle
61.14	2.29e-02	GO:0034385	triglyceride-rich lipoprotein particle
50.04	3.45e-02	GO:0034364	high-density lipoprotein particle

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
549.96	1.23e-04	GO:0060230	lipoprotein lipase activator activity
220.01	1.23e-03	GO:0060229	lipase activator activity
12.43	1.43e-03	GO:0004857	enzyme inhibitor activity
19.51	1.69e-03	GO:0004866	endopeptidase inhibitor activity
19.17	1.81e-03	GO:0030414	peptidase inhibitor activity
18.68	2.00e-03	GO:0061135	endopeptidase regulator activity
15.43	4.23e-03	GO:0061134	peptidase regulator activity