Motif ID: FOXL1.p2

Z-value: 1.098


Transcription factors associated with FOXL1.p2:

Gene SymbolEntrez IDGene Name
FOXL1 2300 forkhead box L1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXL1chr16_+_86612114-0.421.1e-01Click!


Activity profile for motif FOXL1.p2.

activity profile for motif FOXL1.p2


Sorted Z-values histogram for motif FOXL1.p2

Sorted Z-values for motif FOXL1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXL1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_84035888 3.942 PLAC8
placenta-specific 8
chr4_+_74269971 3.352 NM_000477
ALB
albumin
chr4_-_84035908 3.235 NM_001130715
NM_016619
PLAC8

placenta-specific 8

chr4_-_71532206 3.235 IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr17_-_29641087 3.112 EVI2B
ecotropic viral integration site 2B
chr7_+_45933096 2.492


chr17_-_29641094 2.387 NM_006495
EVI2B
ecotropic viral integration site 2B
chr4_-_71532341 2.365 NM_144646
IGJ
immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides
chr10_-_98031154 2.213 NM_001114094
NM_013314
BLNK

B-cell linker

chr17_-_29641068 2.191 EVI2B
ecotropic viral integration site 2B
chr5_-_111091947 2.118 NM_001142483
C5orf13
chromosome 5 open reading frame 13
chr13_-_99959649 2.043 NM_004951
GPR183
G protein-coupled receptor 183
chr19_+_39899749 1.794


chr2_+_33661392 1.760 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr4_-_110723127 1.576 CFI
complement factor I
chr5_-_94224601 1.554 MCTP1
multiple C2 domains, transmembrane 1
chr1_+_192544856 1.553 NM_002922
RGS1
regulator of G-protein signaling 1
chr5_-_94417185 1.522 MCTP1
multiple C2 domains, transmembrane 1
chr2_+_143886898 1.330 NM_018460
ARHGAP15
Rho GTPase activating protein 15
chr12_+_25205180 1.308 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chr14_+_21249209 1.307 NM_005615
RNASE6
ribonuclease, RNase A family, k6
chr2_+_33738941 1.304 NM_015376
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr14_+_88471467 1.304 NM_003608
GPR65
G protein-coupled receptor 65
chr12_+_60083125 1.296 NM_004731
SLC16A7
solute carrier family 16, member 7 (monocarboxylic acid transporter 2)
chr2_-_89165652 1.286


chr1_-_161193375 1.236 NM_001643
APOA2
apolipoprotein A-II
chr13_-_48987247 1.187 LPAR6
lysophosphatidic acid receptor 6
chr1_+_183114214 1.155 LAMC1
laminin, gamma 1 (formerly LAMB2)
chr3_-_148939784 1.152 NM_000096
CP
ceruloplasmin (ferroxidase)
chr2_-_99279935 1.133 NM_001160154
MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr5_+_156696351 1.124 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr13_-_48987017 1.046 LPAR6
lysophosphatidic acid receptor 6
chr4_+_74270832 1.043 ALB
albumin
chr14_+_21156922 0.949 NM_001097577
NM_194431
ANG
RNASE4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family, 4
chr11_+_22688156 0.942 NM_001143830
GAS2
growth arrest-specific 2
chr2_+_143886969 0.939 ARHGAP15
Rho GTPase activating protein 15
chr6_-_32557431 0.923 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chr1_-_161193190 0.919 APOA2
apolipoprotein A-II
chr8_+_74903563 0.918 NM_001195797
NM_015364
LY96

lymphocyte antigen 96

chr8_-_102803196 0.913 NCALD
neurocalcin delta
chr3_-_114790221 0.897 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr11_+_7618416 0.888 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr14_-_107113943 0.879 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr4_+_68424444 0.878 NM_012108
STAP1
signal transducing adaptor family member 1
chr14_-_106471439 0.858 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr14_-_106774311 0.856 IGHA1
immunoglobulin heavy constant alpha 1
chr8_-_102803178 0.855 NCALD
neurocalcin delta
chrM_+_12283 0.849


chr13_-_48987652 0.848 NM_001162498
LPAR6
lysophosphatidic acid receptor 6
chr2_+_24807345 0.847 NM_003743
NM_147223
NM_147233
NCOA1


nuclear receptor coactivator 1


chr19_+_50922194 0.810 NM_001243998
NM_001243999
NM_001244000
NM_003121
SPIB



Spi-B transcription factor (Spi-1/PU.1 related)



chr1_-_207095198 0.797 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr3_-_121379757 0.776 NM_005335
HCLS1
hematopoietic cell-specific Lyn substrate 1
chr14_-_106733392 0.775 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr9_+_19290748 0.743 NM_017925
DENND4C
DENN/MADD domain containing 4C
chr4_+_155484131 0.742 NM_001184741
NM_005141
FGB

fibrinogen beta chain

chr15_-_77176191 0.734 NM_020843
SCAPER
S-phase cyclin A-associated protein in the ER
chr8_-_102803438 0.726 NM_032041
NCALD
neurocalcin delta
chr9_-_36375965 0.719 RNF38
ring finger protein 38
chr14_-_23285011 0.717 NM_001126105
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr4_-_110723334 0.703 NM_000204
CFI
complement factor I
chr4_-_155533882 0.678 NM_000509
NM_021870
FGG

fibrinogen gamma chain

chr4_-_155533800 0.675 FGG
fibrinogen gamma chain
chr3_-_121379701 0.672 HCLS1
hematopoietic cell-specific Lyn substrate 1
chr13_+_76334796 0.669 NM_015842
LMO7
LIM domain 7
chr4_-_155533757 0.666 FGG
fibrinogen gamma chain
chr17_-_64225496 0.664 NM_000042
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr16_+_12058963 0.661 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr14_-_95599794 0.654 NM_001195573
DICER1
dicer 1, ribonuclease type III
chrX_+_37639246 0.649 NM_000397
CYBB
cytochrome b-245, beta polypeptide
chr14_+_100563817 0.638 EVL
Enah/Vasp-like
chr12_+_25205488 0.638 LRMP
lymphoid-restricted membrane protein
chr7_-_37025696 0.638 ELMO1
engulfment and cell motility 1
chr14_-_107131217 0.635 IGHA1
immunoglobulin heavy constant alpha 1
chr1_-_160617042 0.633 NM_003037
SLAMF1
signaling lymphocytic activation molecule family member 1
chr10_-_116444112 0.633 ABLIM1
actin binding LIM protein 1
chr4_-_155533850 0.610 FGG
fibrinogen gamma chain
chr10_-_116444374 0.609 NM_001003407
NM_001003408
ABLIM1

actin binding LIM protein 1

chr3_-_158390266 0.601 NM_020169
LXN
latexin
chr3_-_12941547 0.591 IQSEC1
IQ motif and Sec7 domain 1
chr13_-_75901897 0.591 TBC1D4
TBC1 domain family, member 4
chr3_-_197300193 0.590 NM_203315
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr1_-_230849863 0.590 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr12_+_9822205 0.589 NM_001197318
NM_013269
NM_001004419
NM_001197317
NM_001197319
CLEC2D




C-type lectin domain family 2, member D




chr3_-_78666943 0.586 ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr6_-_133078894 0.584 NM_001242350
NM_004665
VNN2

vanin 2

chr13_-_46742678 0.582 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_+_112051914 0.575 NM_001004196
NM_005944
CD200

CD200 molecule

chr1_-_163172863 0.568 NM_003617
RGS5
regulator of G-protein signaling 5
chr14_-_106405633 0.557 IGHM
immunoglobulin heavy constant mu
chr4_-_16900028 0.553 LDB2
LIM domain binding 2
chr12_-_9268513 0.550 A2M
alpha-2-macroglobulin
chr3_-_58200397 0.550 NM_004944
DNASE1L3
deoxyribonuclease I-like 3
chr1_-_150738292 0.540 NM_001199739
NM_004079
CTSS

cathepsin S

chr8_+_40010986 0.540 NM_020130
C8orf4
chromosome 8 open reading frame 4
chr9_+_79968344 0.536 VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr5_+_92918924 0.535 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr7_+_116660291 0.534 ST7
suppression of tumorigenicity 7
chr2_+_228192227 0.529 NM_020194
MFF
mitochondrial fission factor
chr5_-_150521200 0.528 NM_001193544
ANXA6
annexin A6
chr1_-_57045129 0.523 PPAP2B
phosphatidic acid phosphatase type 2B
chr1_-_27240430 0.513 NM_021969
NR0B2
nuclear receptor subfamily 0, group B, member 2
chr15_-_60919642 0.507 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chr1_+_15990300 0.506


chr6_-_32812711 0.496 NM_004159
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr8_-_82395401 0.492 NM_001442
FABP4
fatty acid binding protein 4, adipocyte
chr12_-_9268522 0.492 NM_000014
A2M
alpha-2-macroglobulin
chrX_+_37639306 0.490 CYBB
cytochrome b-245, beta polypeptide
chrX_-_135863502 0.489 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr4_+_37892698 0.488 NM_015173
TBC1D1
TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1
chr14_-_106539099 0.487 IGHA1
IGHG1
IGHG3
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr5_-_88119604 0.480 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr17_-_29648631 0.477 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr6_-_116447225 0.475 NM_000493
COL10A1
collagen, type X, alpha 1
chr7_+_73624086 0.470 NM_014146
NM_032463
NM_032464
LAT2


linker for activation of T cells family, member 2


chr10_-_116418056 0.466 NM_002313
ABLIM1
actin binding LIM protein 1
chr10_-_52645430 0.465 NM_001198818
NM_001198819
NM_001198820
NM_014576
NM_138932
NM_138933
A1CF





APOBEC1 complementation factor





chr13_-_46679143 0.464 NM_001872
NM_016413
CPB2

carboxypeptidase B2 (plasma)

chr2_-_88427535 0.462 NM_001443
FABP1
fatty acid binding protein 1, liver
chr5_+_67586466 0.454 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_-_149889362 0.434 NM_014849
SV2A
synaptic vesicle glycoprotein 2A
chr11_+_99426872 0.430 NM_175566
CNTN5
contactin 5
chr14_+_64680858 0.429 NM_182913
SYNE2
spectrin repeat containing, nuclear envelope 2
chrX_-_33229428 0.427 NM_004006
DMD
dystrophin
chr1_-_169555710 0.426 NM_000130
F5
coagulation factor V (proaccelerin, labile factor)
chr7_+_90338711 0.421 NM_012395
CDK14
cyclin-dependent kinase 14
chr13_-_99910548 0.421 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr14_+_75988838 0.415 BATF
basic leucine zipper transcription factor, ATF-like
chr12_-_9268475 0.413 A2M
alpha-2-macroglobulin
chr5_-_94417544 0.411 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr2_+_237478379 0.410 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr15_-_90349819 0.410 ANPEP
alanyl (membrane) aminopeptidase
chr1_+_81771844 0.409 LPHN2
latrophilin 2
chr1_-_57045214 0.405 PPAP2B
phosphatidic acid phosphatase type 2B
chr2_-_133429069 0.401 NM_001077427
LYPD1
LY6/PLAUR domain containing 1
chr14_-_106967528 0.400 IGHA1
IGHA2
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr8_+_17822093 0.396 PCM1
pericentriolar material 1
chr12_-_9268440 0.396 A2M
alpha-2-macroglobulin
chr2_-_158300517 0.393 NM_004288
CYTIP
cytohesin 1 interacting protein
chr14_+_75988765 0.392 NM_006399
BATF
basic leucine zipper transcription factor, ATF-like
chr6_+_12717036 0.391 NM_001242648
NM_030948
PHACTR1

phosphatase and actin regulator 1

chr5_+_67588395 0.391 NM_001242466
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr1_+_198608136 0.389 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr1_-_169555624 0.376 F5
coagulation factor V (proaccelerin, labile factor)
chr15_+_100173182 0.375 NM_001130928
MEF2A
myocyte enhancer factor 2A
chr22_+_23054862 0.373 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr6_+_6588933 0.372 NM_004271
LY86
lymphocyte antigen 86
chr10_+_57358749 0.369 NM_001190478
MTRNR2L5
MT-RNR2-like 5
chr11_-_76381787 0.369 NM_001128922
LRRC32
leucine rich repeat containing 32
chr3_+_121774208 0.368 NM_001206924
NM_001206925
NM_175862
CD86


CD86 molecule


chr10_-_45474210 0.365 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr17_+_34538464 0.363 NM_207007
NM_001001435
CCL4L2
CCL4L1
chemokine (C-C motif) ligand 4-like 2
chemokine (C-C motif) ligand 4-like 1
chr14_-_106641585 0.362 IGHV4-31
IGHA1
IGHA2
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant alpha 2 (A2m marker)
immunoglobulin heavy constant gamma 1 (G1m marker)
chr6_+_36644236 0.358 NM_001220777
NM_078467
CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

chr1_-_89591685 0.356 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr2_+_152214105 0.354 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr2_+_189839078 0.353 NM_000090
COL3A1
collagen, type III, alpha 1
chr4_+_71062241 0.352 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr16_+_72088507 0.351 NM_001126102
NM_005143
HP

haptoglobin

chr3_-_49459870 0.351 AMT
aminomethyltransferase
chr13_-_46756326 0.350 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr3_+_132318980 0.347 NM_178445
CCRL1
chemokine (C-C motif) receptor-like 1
chr12_+_111843743 0.342 NM_005475
SH2B3
SH2B adaptor protein 3
chr9_+_71819926 0.341 NM_001170415
NM_001170416
TJP2

tight junction protein 2 (zona occludens 2)

chr8_+_107738239 0.341 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr3_-_49460110 0.340 NM_000481
NM_001164710
NM_001164711
NM_001164712
AMT



aminomethyltransferase



chr8_-_28347733 0.339 NM_172366
FBXO16
ZNF395
F-box protein 16
zinc finger protein 395
chr17_-_9929567 0.338 NM_001130831
GAS7
growth arrest-specific 7
chr1_-_150738232 0.338 CTSS
cathepsin S
chr6_-_75965845 0.335 TMEM30A
transmembrane protein 30A
chr12_-_91573264 0.333 NM_133503
DCN
decorin
chr1_+_160336856 0.331 NM_005598
NHLH1
nescient helix loop helix 1
chr15_+_86220267 0.329 NM_144767
AKAP13
A kinase (PRKA) anchor protein 13
chr4_-_39033981 0.328 NM_024943
TMEM156
transmembrane protein 156
chr5_-_88199868 0.326 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr2_+_20646831 0.324 NM_004040
RHOB
ras homolog gene family, member B
chr20_-_18477811 0.324 NM_006606
RBBP9
retinoblastoma binding protein 9
chr1_-_163172624 0.323 NM_001195303
RGS5
regulator of G-protein signaling 5
chr1_+_156123321 0.323 NM_001193300
NM_022367
NM_001193302
SEMA4A


sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A


chr1_-_230849847 0.323 AGT
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr9_-_5304579 0.322 NM_005059
NM_134441
RLN2

relaxin 2

chr15_-_80263460 0.320 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr9_-_123812535 0.319 NM_001735
C5
complement component 5
chr4_+_69962191 0.318 NM_001074
UGT2B7
UDP glucuronosyltransferase 2 family, polypeptide B7
chr15_-_37391893 0.317 MEIS2
Meis homeobox 2
chr5_-_169724782 0.316 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr14_-_106746056 0.308


chr15_-_70994608 0.304 NM_001008224
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr2_-_20527120 0.304 NM_015317
PUM2
pumilio homolog 2 (Drosophila)
chr6_-_22297729 0.303 NM_000948
PRL
prolactin
chr10_-_14050453 0.303 FRMD4A
FERM domain containing 4A
chr6_-_131291480 0.301 NM_001199389
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr22_+_40322609 0.296 GRAP2
GRB2-related adaptor protein 2
chr1_-_168513201 0.295 NM_003175
XCL1
XCL2
chemokine (C motif) ligand 1
chemokine (C motif) ligand 2
chr1_-_151414641 0.295 NM_207171
POGZ
pogo transposable element with ZNF domain
chr5_-_169724817 0.291 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr5_-_169724734 0.287 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr1_+_198608216 0.286 PTPRC
protein tyrosine phosphatase, receptor type, C
chr10_+_97515408 0.286 NM_001164178
NM_001164181
NM_001164179
NM_001164182
NM_001164183
NM_001776
ENTPD1





ectonucleoside triphosphate diphosphohydrolase 1





chr21_-_27253197 0.283 APP
amyloid beta (A4) precursor protein

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.