Motif ID: FOXP3.p2

Z-value: 0.798


Transcription factors associated with FOXP3.p2:

Gene SymbolEntrez IDGene Name
FOXP3 50943 forkhead box P3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXP3chrX_-_491211710.058.7e-01Click!


Activity profile for motif FOXP3.p2.

activity profile for motif FOXP3.p2


Sorted Z-values histogram for motif FOXP3.p2

Sorted Z-values for motif FOXP3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXP3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_32497925 2.331 NM_002125
HLA-DRB5
major histocompatibility complex, class II, DR beta 5
chr17_-_29641087 2.263 EVI2B
ecotropic viral integration site 2B
chr17_-_29641094 2.232 NM_006495
EVI2B
ecotropic viral integration site 2B
chr17_-_29641068 2.191 EVI2B
ecotropic viral integration site 2B
chr2_-_158300517 1.871 NM_004288
CYTIP
cytohesin 1 interacting protein
chr6_-_32557431 1.752 NM_001243965
NM_002124
HLA-DRB1

HLA-DRB4
HLA-DRB5
major histocompatibility complex, class II, DR beta 1

major histocompatibility complex, class II, DR beta 4
major histocompatibility complex, class II, DR beta 5
chrX_-_100641143 1.746 NM_000061
BTK
Bruton agammaglobulinemia tyrosine kinase
chr7_-_150329285 1.504 GIMAP6
GTPase, IMAP family member 6
chr4_+_40198526 1.406 NM_004310
RHOH
ras homolog gene family, member H
chr6_-_154677868 1.238 NM_001130700
NM_015553
IPCEF1

interaction protein for cytohesin exchange factors 1

chr7_-_150329735 1.217 NM_001244071
NM_001244072
NM_024711
GIMAP6


GTPase, IMAP family member 6


chr2_-_21225640 1.177 APOB
apolipoprotein B (including Ag(x) antigen)
chr22_+_21128378 1.159 NM_000185
SERPIND1
serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr10_+_114135013 1.114 NM_203380
ACSL5
acyl-CoA synthetase long-chain family member 5
chr1_+_15990300 1.065


chr1_+_207627614 1.022 NM_001006658
NM_001877
CR2

complement component (3d/Epstein Barr virus) receptor 2

chr7_+_26400503 0.905 NM_001199837
SNX10
sorting nexin 10
chr16_+_72088507 0.845 NM_001126102
NM_005143
HP

haptoglobin

chr11_+_116700620 0.829 NM_000040
APOC3
apolipoprotein C-III
chr15_-_93277303 0.823 FAM174B
family with sequence similarity 174, member B
chr4_+_88896801 0.797 NM_000582
NM_001040058
NM_001040060
NM_001251829
NM_001251830
SPP1




secreted phosphoprotein 1




chr4_+_15779887 0.774 NM_001775
CD38
CD38 molecule
chr9_-_116840545 0.721 AMBP
alpha-1-microglobulin/bikunin precursor
chr1_+_174844655 0.697 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr6_+_64356430 0.686 NM_015153
PHF3
PHD finger protein 3
chr1_+_192544856 0.675 NM_002922
RGS1
regulator of G-protein signaling 1
chr1_-_207095198 0.662 NM_001193338
NM_001142473
NM_005449
FAIM3


Fas apoptotic inhibitory molecule 3


chr9_-_36375965 0.636 RNF38
ring finger protein 38
chr9_-_116840551 0.615 AMBP
alpha-1-microglobulin/bikunin precursor
chr9_-_116840460 0.604 AMBP
alpha-1-microglobulin/bikunin precursor
chr15_-_80263460 0.568 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr1_-_150738232 0.533 CTSS
cathepsin S
chr1_-_150738292 0.529 NM_001199739
NM_004079
CTSS

cathepsin S

chr8_+_107738239 0.525 NM_001198534
NM_001198535
OXR1

oxidation resistance 1

chr11_+_124824012 0.500 NM_025004
CCDC15
coiled-coil domain containing 15
chr12_+_100897137 0.500 NM_001206992
NM_001206993
NR1H4

nuclear receptor subfamily 1, group H, member 4

chr9_-_116840604 0.479 AMBP
alpha-1-microglobulin/bikunin precursor
chr4_+_88896838 0.466 SPP1
secreted phosphoprotein 1
chr17_-_10421858 0.465 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr4_+_88896899 0.452 SPP1
secreted phosphoprotein 1
chr12_+_100867739 0.446 NR1H4
nuclear receptor subfamily 1, group H, member 4
chr6_+_87969619 0.421 ZNF292
zinc finger protein 292
chr16_+_15068832 0.413 NM_015027
PDXDC1
pyridoxal-dependent decarboxylase domain containing 1
chr4_-_186697065 0.388 NM_001145673
SORBS2
sorbin and SH3 domain containing 2
chr4_+_70146216 0.385 NM_001207004
NM_053039
UGT2B28

UDP glucuronosyltransferase 2 family, polypeptide B28

chr6_+_33043702 0.375 NM_002121
HLA-DPB1
major histocompatibility complex, class II, DP beta 1
chr19_+_42381189 0.347 NM_001783
NM_021601
CD79A

CD79a molecule, immunoglobulin-associated alpha

chr12_+_6554032 0.339 NM_001242
CD27
CD27 molecule
chr9_-_116840673 0.337 NM_001633
AMBP
alpha-1-microglobulin/bikunin precursor
chr2_+_143635194 0.336 NM_001032998
NM_001199241
NM_003937
KYNU


kynureninase


chr17_+_27369917 0.333 NM_016518
PIPOX
pipecolic acid oxidase
chr17_+_41052813 0.332 NM_000151
G6PC
glucose-6-phosphatase, catalytic subunit
chr11_+_124824076 0.327 CCDC15
coiled-coil domain containing 15
chr1_-_160549226 0.296 CD84
CD84 molecule
chr14_-_21899866 0.293 NM_001170629
CHD8
chromodomain helicase DNA binding protein 8
chr12_+_15475445 0.288 PTPRO
protein tyrosine phosphatase, receptor type, O
chr6_-_112041253 0.287 NM_153047
FYN
FYN oncogene related to SRC, FGR, YES
chrX_-_106960268 0.286 NM_004089
TSC22D3
TSC22 domain family, member 3
chr3_-_121264780 0.280 NM_199420
POLQ
polymerase (DNA directed), theta
chr6_-_11382501 0.279 NM_001142393
NEDD9
neural precursor cell expressed, developmentally down-regulated 9
chr12_+_100867550 0.266 NM_001206977
NM_001206978
NM_001206979
NM_005123
NR1H4



nuclear receptor subfamily 1, group H, member 4



chr1_-_173886464 0.263 NM_000488
SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr17_+_67410825 0.263 NM_002758
MAP2K6
mitogen-activated protein kinase kinase 6
chr6_-_32634287 0.263 NM_001243961
NM_002123
HLA-DQB1

major histocompatibility complex, class II, DQ beta 1

chr6_-_76203256 0.245 NM_015687
FILIP1
filamin A interacting protein 1
chr16_+_72097124 0.243 NM_020995
HPR
haptoglobin-related protein
chrX_+_78200828 0.231 NM_014499
NM_198333
P2RY10

purinergic receptor P2Y, G-protein coupled, 10

chr2_-_89513056 0.230 IGKC
immunoglobulin kappa constant
chr1_+_116925991 0.228 NM_001160234
ATP1A1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr13_-_99910548 0.226 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr4_+_71062241 0.225 NM_017855
ODAM
odontogenic, ameloblast asssociated
chr14_-_35344852 0.225 NM_013448
NM_182648
BAZ1A

bromodomain adjacent to zinc finger domain, 1A

chrX_-_135863502 0.220 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr4_-_186732047 0.220 NM_001145672
SORBS2
sorbin and SH3 domain containing 2
chr16_-_52581713 0.211 NM_001146188
TOX3
TOX high mobility group box family member 3
chr1_+_198608136 0.211 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr19_-_23578226 0.210 NM_003430
ZNF91
zinc finger protein 91
chr12_+_53497273 0.205 NM_003578
SOAT2
sterol O-acyltransferase 2
chr1_-_160832466 0.204 NM_001166663
NM_001166664
NM_016382
CD244


CD244 molecule, natural killer cell receptor 2B4


chr19_-_6720585 0.201 NM_000064
C3
complement component 3
chr6_+_144612872 0.198 NM_007124
UTRN
utrophin
chr2_-_89619820 0.195 IGKC
immunoglobulin kappa constant
chr10_-_91102430 0.195 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr12_+_51318515 0.190 NM_014033
METTL7A
methyltransferase like 7A
chr8_+_92114846 0.189 NM_001129890
LRRC69
leucine rich repeat containing 69
chr5_-_59783885 0.189 NM_001165899
PDE4D
phosphodiesterase 4D, cAMP-specific
chr8_-_17752847 0.186 NM_147203
NM_201553
NM_004467
NM_201552
FGL1



fibrinogen-like 1



chr16_-_70099755 0.184 PDXDC2P
pyridoxal-dependent decarboxylase domain containing 2, pseudogene
chr5_-_94417185 0.183 MCTP1
multiple C2 domains, transmembrane 1
chr8_+_124194751 0.179 NM_032899
NM_207006
FAM83A

family with sequence similarity 83, member A

chr15_+_58724174 0.173 NM_000236
LIPC
lipase, hepatic
chr1_-_115269672 0.161 CSDE1
cold shock domain containing E1, RNA-binding
chr16_-_12897693 0.155 NM_001099455
NM_018340
CPPED1

calcineurin-like phosphoesterase domain containing 1

chr4_-_103245468 0.154 NM_001135148
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr2_+_170440846 0.153 NM_004792
PPIG
peptidylprolyl isomerase G (cyclophilin G)
chr19_-_55767103 0.152 PPP6R1
protein phosphatase 6, regulatory subunit 1
chr3_+_63884074 0.151 NM_001177387
ATXN7
ataxin 7
chr6_+_106546736 0.147 NM_182907
PRDM1
PR domain containing 1, with ZNF domain
chr6_+_31540092 0.147 NM_000595
LTA
lymphotoxin alpha (TNF superfamily, member 1)
chr5_+_67586466 0.146 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr16_+_31724564 0.145 ZNF720
zinc finger protein 720
chr6_+_31730772 0.142 NM_001039651
C6orf26
chromosome 6 open reading frame 26
chr1_-_161147757 0.136 NM_001199873
NM_001199874
NM_003779
B4GALT3


UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3


chr16_+_2867163 0.136 NM_006799
NM_144956
NM_144957
PRSS21


protease, serine, 21 (testisin)


chr9_+_12693385 0.136 NM_000550
TYRP1
tyrosinase-related protein 1
chr6_-_131384387 0.136 NM_001135554
NM_001135555
NM_001199388
NM_001431
EPB41L2



erythrocyte membrane protein band 4.1-like 2



chr1_-_173886401 0.135 SERPINC1
serpin peptidase inhibitor, clade C (antithrombin), member 1
chr17_+_41006094 0.130 AOC3
amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr16_+_2867227 0.129 PRSS21
protease, serine, 21 (testisin)
chr11_-_47545539 0.128 NM_001172639
CELF1
CUGBP, Elav-like family member 1
chr1_-_78444772 0.127 NM_003902
FUBP1
far upstream element (FUSE) binding protein 1
chr1_-_204459445 0.127 NM_002646
PIK3C2B
phosphoinositide-3-kinase, class 2, beta polypeptide
chr22_-_45608232 0.125 KIAA0930
KIAA0930
chr14_-_106829736 0.124 IGHA1
IGHD
IGHG3
IGHM
SKAP2
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
src kinase associated phosphoprotein 2
chr1_+_244216506 0.124 NM_006352
ZNF238
zinc finger protein 238
chr2_-_215896809 0.124 NM_015657
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr2_+_103035148 0.123 NM_003853
IL18RAP
interleukin 18 receptor accessory protein
chr1_+_66797775 0.122 NM_001037339
PDE4B
phosphodiesterase 4B, cAMP-specific
chrX_-_30595883 0.121 NM_025159
CXorf21
chromosome X open reading frame 21
chr2_+_170366211 0.120 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr17_+_6659356 0.114 XAF1
XIAP associated factor 1
chr8_+_17829848 0.112 PCM1
pericentriolar material 1
chr15_-_65412175 0.108 PDCD7
programmed cell death 7
chr2_-_74382352 0.106


chr1_+_212788359 0.105 NM_001206486
ATF3
activating transcription factor 3
chr13_+_96085852 0.103 NM_001160100
NM_182848
CLDN10

claudin 10

chr2_-_110962577 0.102 NM_000272
NM_001128178
NM_001128179
NM_207181
NPHP1



nephronophthisis 1 (juvenile)



chr8_-_37727937 0.102 RAB11FIP1
RAB11 family interacting protein 1 (class I)
chr12_+_53497287 0.101 SOAT2
sterol O-acyltransferase 2
chr1_-_89591685 0.101 NM_004120
GBP2
guanylate binding protein 2, interferon-inducible
chr19_-_36304200 0.099 NM_021232
PRODH2
proline dehydrogenase (oxidase) 2
chrX_-_135863033 0.099 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr13_+_111839172 0.099 NM_001113513
ARHGEF7
Rho guanine nucleotide exchange factor (GEF) 7
chr3_+_119316694 0.097 NM_001206960
NM_001206961
NM_015900
PLA1A


phospholipase A1 member A


chr6_-_25874439 0.097 NM_001098486
NM_006632
SLC17A3

solute carrier family 17 (sodium phosphate), member 3

chr19_+_34710327 0.097 LSM14A
LSM14A, SCD6 homolog A (S. cerevisiae)
chr19_+_21106058 0.095 NM_003429
ZNF85
zinc finger protein 85
chr10_+_118380451 0.094 NM_005396
PNLIPRP2
pancreatic lipase-related protein 2
chr3_-_178984789 0.093 NM_001163677
NM_171828
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr11_+_87032428 0.093 TMEM135
transmembrane protein 135
chr13_+_49684388 0.092 NM_014923
FNDC3A
fibronectin type III domain containing 3A
chr2_-_166930130 0.091 NM_001165963
NM_001165964
NM_006920
SCN1A


sodium channel, voltage-gated, type I, alpha subunit


chr5_+_157158322 0.091 NM_017872
THG1L
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr10_-_45474210 0.090 NM_007021
C10orf10
chromosome 10 open reading frame 10
chr1_+_52195603 0.089 OSBPL9
oxysterol binding protein-like 9
chr4_+_124317884 0.088 NM_199327
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr17_+_6659155 0.087 NM_017523
NM_199139
XAF1

XIAP associated factor 1

chr4_+_71226477 0.086 NM_012390
SMR3B
SMR3A
submaxillary gland androgen regulated protein 3B
submaxillary gland androgen regulated protein 3A
chr4_-_186732208 0.086 NM_001145671
SORBS2
sorbin and SH3 domain containing 2
chr18_-_74728963 0.084 MBP
myelin basic protein
chr19_+_52266640 0.083 NM_001462
FPR2
formyl peptide receptor 2
chr15_+_85666291 0.081 PDE8A
phosphodiesterase 8A
chr19_-_36303766 0.080 PRODH2
proline dehydrogenase (oxidase) 2
chr17_+_75181294 0.079 NM_001144001
SEC14L1
SEC14-like 1 (S. cerevisiae)
chr1_+_174933904 0.079 NM_001243764
RABGAP1L
RAB GTPase activating protein 1-like
chr15_+_48498497 0.077 NM_000338
NM_001184832
SLC12A1

solute carrier family 12 (sodium/potassium/chloride transporters), member 1

chr19_+_42724431 0.077 NM_133444
ZNF526
zinc finger protein 526
chr17_-_45899133 0.075 NM_145798
OSBPL7
oxysterol binding protein-like 7
chr8_-_90996785 0.074 NBN
nibrin
chr2_+_1418179 0.073 NM_175721
NM_175722
TPO

thyroid peroxidase

chr17_-_45899118 0.073 OSBPL7
oxysterol binding protein-like 7
chr1_-_78444690 0.073 FUBP1
far upstream element (FUSE) binding protein 1
chr3_-_170744767 0.073 NM_000340
SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr14_+_102276279 0.072 PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr4_-_74088773 0.072 ANKRD17
ankyrin repeat domain 17
chr15_+_77287688 0.071 PSTPIP1
proline-serine-threonine phosphatase interacting protein 1
chr3_-_172241060 0.071 NM_001190943
NM_001190942
NM_003810
TNFSF10


tumor necrosis factor (ligand) superfamily, member 10


chr1_-_109935869 0.070 NM_001205228
SORT1
sortilin 1
chr2_+_166152282 0.070 NM_001040143
SCN2A
sodium channel, voltage-gated, type II, alpha subunit
chr2_-_110962539 0.069 NPHP1
nephronophthisis 1 (juvenile)
chr1_-_160549271 0.068 NM_001184879
NM_001184881
NM_001184882
NM_003874
CD84



CD84 molecule



chr11_+_30252562 0.067 NM_000510
NM_001018080
FSHB

follicle stimulating hormone, beta polypeptide

chr16_-_71748697 0.066 NM_015020
PHLPP2
PH domain and leucine rich repeat protein phosphatase 2
chr1_-_203144910 0.065 NM_004997
MYBPH
myosin binding protein H
chr18_+_77441429 0.065 NM_001202504
CTDP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr16_+_70333058 0.064 NM_001014449
NM_001014451
NM_007242
DDX19B


DEAD (Asp-Glu-Ala-As) box polypeptide 19B


chr5_+_115898218 0.062


chr13_+_49280619 0.061 NM_020377
CYSLTR2
cysteinyl leukotriene receptor 2
chr3_-_9885659 0.059 RPUSD3
RNA pseudouridylate synthase domain containing 3
chr3_-_170744458 0.057 SLC2A2
solute carrier family 2 (facilitated glucose transporter), member 2
chr9_-_75567915 0.057 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr4_-_100356290 0.056 NM_001166504
ADH7
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr9_+_134305476 0.056 NM_013318
PRRC2B
proline-rich coiled-coil 2B
chr5_-_32388595 0.054 ZFR
zinc finger RNA binding protein
chr3_+_149192479 0.053 TM4SF4
transmembrane 4 L six family member 4
chr4_-_164534656 0.053 NM_017923
MARCH1
membrane-associated ring finger (C3HC4) 1
chr1_+_67632168 0.053 NM_144701
IL23R
interleukin 23 receptor
chr5_+_40909617 0.052 C7
complement component 7
chr5_+_43602738 0.052 NM_012343
NNT
nicotinamide nucleotide transhydrogenase
chr1_-_182922504 0.051 NM_030933
SHCBP1L
SHC SH2-domain binding protein 1-like
chr7_+_48211054 0.051 NM_152701
ABCA13
ATP-binding cassette, sub-family A (ABC1), member 13
chr9_-_99064385 0.050 NM_000197
HSD17B3
hydroxysteroid (17-beta) dehydrogenase 3
chr10_+_112344076 0.050 SMC3
structural maintenance of chromosomes 3
chrX_-_135863104 0.050 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr19_-_40440532 0.049 NM_003890
FCGBP
Fc fragment of IgG binding protein
chr10_+_51576284 0.049 NM_001145262
NCOA4
nuclear receptor coactivator 4
chr2_-_145052059 0.048 NM_001006636
GTDC1
glycosyltransferase-like domain containing 1
chr17_+_72581056 0.048 NM_152460
C17orf77
chromosome 17 open reading frame 77
chr11_-_113345841 0.048 NM_000795
NM_016574
DRD2

dopamine receptor D2

chr15_+_77287738 0.048 PSTPIP1
proline-serine-threonine phosphatase interacting protein 1

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
139.07 3.49e-03 GO:0042613 MHC class II protein complex
3.01 1.18e-02 GO:0071944 cell periphery
10.51 1.45e-02 GO:0005768 endosome
64.94 1.65e-02 GO:0042611 MHC protein complex
14.25 3.95e-02 GO:0010008 endosome membrane
14.11 4.07e-02 GO:0044440 endosomal part
41.48 4.07e-02 GO:0031902 late endosome membrane

Nothing significant found in function category.