• All motifs sorted by activity significance
• All samples sorted alphabetically
• Mean activities

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
• Download the whole report

Motif ID: HNF1A.p2

Z-value: 4.462

---

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr17_-_64225496	35.441	NM_000042	APOH	apolipoprotein H (beta-2-glycoprotein I)
chr4_+_74301932	32.678	NM_001134	AFP	alpha-fetoprotein
chr4_+_74269971	28.557	NM_000477	ALB	albumin
chr14_-_94854910	28.443		SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chr14_-_94855120	27.871	NM_000295	SERPINA1	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1
chrX_-_105282714	27.687	NM_000354	SERPINA7	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr4_-_155511838	21.621	NM_000508 NM_021871	FGA	fibrinogen alpha chain
chr11_+_46740769	21.367		F2	coagulation factor II (thrombin)
chr4_-_110723127	21.282		CFI	complement factor I
chr8_-_17752847	20.935	NM_147203 NM_201553 NM_004467 NM_201552	FGL1	fibrinogen-like 1
chr7_+_45927958	19.969	NM_000596	IGFBP1	insulin-like growth factor binding protein 1
chr14_-_94789641	19.699	NM_001756	SERPINA6	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6
chr19_-_36303766	19.651		PRODH2	proline dehydrogenase (oxidase) 2
chr9_-_123812535	18.954	NM_001735	C5	complement component 5
chr14_+_21156922	18.787	NM_001097577 NM_194431	ANG RNASE4	angiogenin, ribonuclease, RNase A family, 5 ribonuclease, RNase A family, 4
chr11_+_46740736	18.545	NM_000506	F2	coagulation factor II (thrombin)
chr19_-_36303724	18.346		PRODH2	proline dehydrogenase (oxidase) 2
chr6_+_31623688	18.188		APOM	apolipoprotein M
chr4_-_110723334	17.785	NM_000204	CFI	complement factor I
chr6_+_31623668	17.630	NM_019101	APOM	apolipoprotein M
chr10_+_5136589	14.768		AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr19_+_11350282	14.642	NM_018687	C19orf80	chromosome 19 open reading frame 80
chr15_+_58724174	14.548	NM_000236	LIPC	lipase, hepatic
chr10_+_5136556	14.420	NM_003739	AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr19_-_48389514	14.403		SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr10_+_5136613	14.085		AKR1C3	aldo-keto reductase family 1, member C3 (3-alpha hydroxysteroid dehydrogenase, type II)
chr19_-_48389571	14.050	NM_003167	SULT2A1	sulfotransferase family, cytosolic, 2A, dehydroepiandrosterone (DHEA)-preferring, member 1
chr10_-_52645384	13.466		A1CF	APOBEC1 complementation factor
chr10_-_52645430	13.417	NM_001198818 NM_001198819 NM_001198820 NM_014576 NM_138932 NM_138933	A1CF	APOBEC1 complementation factor
chr17_+_41052813	13.026	NM_000151	G6PC	glucose-6-phosphatase, catalytic subunit
chr2_-_88427535	12.999	NM_001443	FABP1	fatty acid binding protein 1, liver
chr17_+_1646129	12.589	NM_000934 NM_001165921	SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr4_-_69817478	12.456	NM_024743	UGT2A3	UDP glucuronosyltransferase 2 family, polypeptide A3
chr4_+_155484131	12.003	NM_001184741 NM_005141	FGB	fibrinogen beta chain
chr14_-_94759594	11.590	NM_001100607	SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr1_+_207277577	11.433	NM_000715	C4BPA	complement component 4 binding protein, alpha
chr14_-_94759556	11.073		SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr14_-_94759360	10.957	NM_016186	SERPINA10	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr4_+_69962191	10.929	NM_001074	UGT2B7	UDP glucuronosyltransferase 2 family, polypeptide B7
chr14_+_95027760	10.897	NM_006215	SERPINA4	serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 4
chr10_+_101542460	10.665	NM_000392	ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr18_+_29171729	10.406	NM_000371	TTR	transthyretin
chr16_-_87970107	9.701	NM_001739	CA5A	carbonic anhydrase VA, mitochondrial
chr19_-_36304200	8.331	NM_021232	PRODH2	proline dehydrogenase (oxidase) 2
chr15_-_90349819	8.193		ANPEP	alanyl (membrane) aminopeptidase
chr17_+_73553883	8.132		LLGL2	lethal giant larvae homolog 2 (Drosophila)
chr10_+_101542554	7.920		ABCC2	ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr1_+_17906941	7.913	NM_001011722	ARHGEF10L	Rho guanine nucleotide exchange factor (GEF) 10-like
chr4_-_186733372	7.703	NM_003603 NM_001145670	SORBS2	sorbin and SH3 domain containing 2
chr2_+_102508333	7.602		MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chrX_+_70435048	7.305	NM_001097642	GJB1	gap junction protein, beta 1, 32kDa
chr1_+_207262211	7.292	NM_001017365 NM_001017366	C4BPB	complement component 4 binding protein, beta
chr17_+_1646290	6.883	NM_001165920	SERPINF2	serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2
chr8_-_17555158	6.658	NM_020749	MTUS1	microtubule associated tumor suppressor 1
chrX_+_70435087	6.361		GJB1	gap junction protein, beta 1, 32kDa
chr7_-_50633042	6.196	NM_001082971	DDC	dopa decarboxylase (aromatic L-amino acid decarboxylase)
chr11_-_117695408	6.049	NM_001680	FXYD2	FXYD domain containing ion transport regulator 2
chr4_-_70080448	6.008	NM_001073	UGT2B11 UGT2B10	UDP glucuronosyltransferase 2 family, polypeptide B11 UDP glucuronosyltransferase 2 family, polypeptide B10
chr2_+_102508377	5.802		MAP4K4	mitogen-activated protein kinase kinase kinase kinase 4
chr7_+_94292737	5.797		PEG10	paternally expressed 10
chr19_-_39443326	5.694	NM_148169	FBXO17	F-box protein 17
chr8_+_21911062	5.594	NM_001114137	EPB49	erythrocyte membrane protein band 4.9 (dematin)
chr4_+_187187117	5.512	NM_000128	F11	coagulation factor XI
chr7_-_44580857	5.428	NM_001101648 NM_013389	NPC1L1	NPC1 (Niemann-Pick disease, type C1, gene)-like 1
chr19_+_45417576	5.331		APOC1	apolipoprotein C-I
chr6_-_25930838	5.102	NM_005835	SLC17A2	solute carrier family 17 (sodium phosphate), member 2
chr6_+_167704802	5.064	NM_001143947 NM_018974	UNC93A	unc-93 homolog A (C. elegans)
chr4_+_74270832	4.540		ALB	albumin
chr5_+_175976342	4.495	NM_017675	CDHR2	cadherin-related family member 2
chr2_+_62934030	4.445	NM_001142614	EHBP1	EH domain binding protein 1
chr20_-_17641122	4.425		RRBP1	ribosome binding protein 1 homolog 180kDa (dog)
chrX_-_131547536	4.416	NM_001170701 NM_001170702 NM_001170703	MBNL3	muscleblind-like 3 (Drosophila)
chr2_-_169103886	4.193	NM_013233	STK39	serine threonine kinase 39
chr5_-_147211141	3.991		SPINK1	serine peptidase inhibitor, Kazal type 1
chr2_-_162931051	3.834	NM_001935	DPP4	dipeptidyl-peptidase 4
chr1_-_230849847	3.834		AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr16_+_30210548	3.681	NM_001017390 NM_177552	SULT1A4 SULT1A3	sulfotransferase family, cytosolic, 1A, phenol-preferring, member 4 sulfotransferase family, cytosolic, 1A, phenol-preferring, member 3
chr2_+_27719702	3.664	NM_001486	GCKR	glucokinase (hexokinase 4) regulator
chrX_+_107683015	3.600	NM_000495 NM_033380	COL4A5	collagen, type IV, alpha 5
chr6_+_158733691	3.521	NM_001007466 NM_020245	TULP4	tubby like protein 4
chr16_+_89696775	3.384		DPEP1	dipeptidase 1 (renal)
chr6_+_161123224	3.326	NM_000301 NM_001168338	PLG	plasminogen
chr16_+_89696674	3.304		DPEP1	dipeptidase 1 (renal)
chr17_-_202557	3.285		RPH3AL	rabphilin 3A-like (without C2 domains)
chr15_+_59903980	3.231	NM_004751	GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chr5_-_147211235	3.140	NM_003122	SPINK1	serine peptidase inhibitor, Kazal type 1
chr19_-_33360641	2.963	NM_001126335 NM_001243036 NM_014270	SLC7A9	solute carrier family 7 (glycoprotein-associated amino acid transporter light chain, bo,+ system), member 9
chr11_+_121461070	2.961		SORL1	sortilin-related receptor, L(DLR class) A repeats containing
chr7_-_156801980	2.958	NM_001165255	MNX1	motor neuron and pancreas homeobox 1
chr6_+_64231626	2.902		PTP4A1	protein tyrosine phosphatase type IVA, member 1
chr5_+_73109342	2.896	NM_001244364	RGNEF	190 kDa guanine nucleotide exchange factor
chr1_-_230849863	2.777		AGT	angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr20_-_22564893	2.574		FOXA2	forkhead box A2
chr14_+_39735500	2.526	NM_001247988 NM_203356	CTAGE5	CTAGE family, member 5
chr6_+_131894343	2.455	NM_000045 NM_001244438	ARG1	arginase, liver
chr6_+_167536240	2.430	NM_031409	CCR6	chemokine (C-C motif) receptor 6
chr11_+_22688156	2.356	NM_001143830	GAS2	growth arrest-specific 2
chr20_+_56136136	2.314	NM_002591	PCK1	phosphoenolpyruvate carboxykinase 1 (soluble)
chr17_-_202617	2.231	NM_001190411 NM_001190412 NM_001190413 NM_006987	RPH3AL	rabphilin 3A-like (without C2 domains)
chr6_-_25874439	2.180	NM_001098486 NM_006632	SLC17A3	solute carrier family 17 (sodium phosphate), member 3
chr4_+_124317884	2.139	NM_199327	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr2_-_162930544	2.139		DPP4	dipeptidyl-peptidase 4
chr4_+_187187342	2.123		F11	coagulation factor XI
chr8_-_18541441	2.117		PSD3	pleckstrin and Sec7 domain containing 3
chr12_-_12291374	2.092		LRP6	low density lipoprotein receptor-related protein 6
chr5_+_176513819	2.080	NM_002011 NM_213647	FGFR4	fibroblast growth factor receptor 4
chr12_-_71551564	2.007		TSPAN8	tetraspanin 8
chr3_-_50340979	1.969	NM_007312 NM_033159 NM_153282 NM_153283 NM_153285	HYAL1	hyaluronoglucosaminidase 1
chr3_-_52294427	1.900		WDR82	WD repeat domain 82
chr7_+_120629444	1.795	NM_001105533	C7orf58	chromosome 7 open reading frame 58
chr20_+_62371109	1.793	NM_020062	SLC2A4RG	SLC2A4 regulator
chr1_-_43424324	1.786		SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1
chr3_+_12392993	1.745	NM_015869	PPARG	peroxisome proliferator-activated receptor gamma
chr20_+_62371218	1.734		SLC2A4RG	SLC2A4 regulator
chr6_-_52628272	1.696	NM_000846	GSTA2	glutathione S-transferase alpha 2
chrX_-_33146543	1.690	NM_004010 NM_004009	DMD	dystrophin
chrX_+_2958274	1.683	NM_001201538	ARSF	arylsulfatase F
chr15_-_51397472	1.615	NM_207381	TNFAIP8L3	tumor necrosis factor, alpha-induced protein 8-like 3
chr12_-_24102563	1.589	NM_006940	SOX5	SRY (sex determining region Y)-box 5
chr18_-_46469118	1.573	NM_001190823	SMAD7	SMAD family member 7
chr20_+_35973083	1.501	NM_005417	SRC	v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr22_-_43355886	1.309	NM_001184971	PACSIN2	protein kinase C and casein kinase substrate in neurons 2
chr4_+_3443659	1.257		HGFAC	HGF activator
chr1_+_54359859	1.237	NM_000792 NM_001039715 NM_001039716 NM_213593	DIO1	deiodinase, iodothyronine, type I
chr4_+_3443691	1.231	NM_001528	HGFAC	HGF activator
chr14_-_20801427	1.177	NM_021178 NM_182849	CCNB1IP1	cyclin B1 interacting protein 1, E3 ubiquitin protein ligase
chr17_-_8424217	1.161		MYH10	myosin, heavy chain 10, non-muscle
chr1_-_20141593	1.150	NM_019062	RNF186	ring finger protein 186
chr16_-_57836380	1.147	NM_001130100 NM_005550	KIFC3	kinesin family member C3
chr1_+_81771844	1.127		LPHN2	latrophilin 2
chr4_-_166034003	1.127	NM_001100389	TMEM192	transmembrane protein 192
chr19_+_50016500	1.114		FCGRT	Fc fragment of IgG, receptor, transporter, alpha
chrX_+_107288199	1.101	NM_001170553 NM_182607	VSIG1	V-set and immunoglobulin domain containing 1
chr16_+_20775311	1.073	NM_005622 NM_202000	ACSM3	acyl-CoA synthetase medium-chain family member 3
chr3_+_119499330	1.072	NM_003889 NM_033013	NR1I2	nuclear receptor subfamily 1, group I, member 2
chr11_-_102323353	1.037	NM_052932	TMEM123	transmembrane protein 123
chr20_+_2944918	0.995		PTPRA	protein tyrosine phosphatase, receptor type, A
chr4_-_166033924	0.939		TMEM192	transmembrane protein 192
chr3_+_187943192	0.916	NM_001167671	LPP	LIM domain containing preferred translocation partner in lipoma
chr4_-_10686314	0.857	NM_052964	CLNK	cytokine-dependent hematopoietic cell linker
chr12_-_71551778	0.839	NM_004616	TSPAN8	tetraspanin 8
chr18_+_77866914	0.838	NM_014913	ADNP2	ADNP homeobox 2
chr3_-_150966901	0.837	NM_001081455	P2RY14	purinergic receptor P2Y, G-protein coupled, 14
chr6_+_54173202	0.825	NM_014464	TINAG	tubulointerstitial nephritis antigen
chr16_-_57836370	0.819		KIFC3	kinesin family member C3
chr5_-_78282356	0.813	NM_000046	ARSB	arylsulfatase B
chr16_-_57831675	0.773	NM_001130099	KIFC3	kinesin family member C3
chr7_+_130126035	0.759	NM_177524	MEST	mesoderm specific transcript homolog (mouse)
chr16_+_22524843	0.728	NM_001135865	LOC100132247 NPIPL3	nuclear pore complex interacting protein related gene nuclear pore complex interacting protein-like 3
chr16_+_31404596	0.719	NM_005353	ITGAD	integrin, alpha D
chr6_+_31707724	0.697	NM_002441 NM_025259 NM_172165 NM_172166	MSH5-C6orf26 MSH5	MSH5-C6orf26 readthrough (non-protein coding) mutS homolog 5 (E. coli)
chr11_-_118900078	0.661	NM_001164280	SLC37A4	solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr20_-_4990913	0.659	NM_203327	SLC23A2	solute carrier family 23 (nucleobase transporters), member 2
chr15_+_59904090	0.643		GCNT3	glucosaminyl (N-acetyl) transferase 3, mucin type
chr1_+_212475147	0.635	NM_001199756	PPP2R5A	protein phosphatase 2, regulatory subunit B', alpha
chr6_-_119470336	0.627	NM_001100411	FAM184A	family with sequence similarity 184, member A
chr16_-_21436657	0.607	NM_130464	NPIPL3	nuclear pore complex interacting protein-like 3
chr22_+_31366662	0.603
chr22_-_38881529	0.574		DDX17	DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr5_-_111093792	0.573	NM_001142477 NM_001142476	C5orf13	chromosome 5 open reading frame 13
chr20_+_42187705	0.538		SGK2	serum/glucocorticoid regulated kinase 2
chr16_-_72206023	0.533	NM_031293	PMFBP1	polyamine modulated factor 1 binding protein 1
chr11_+_119056165	0.530	NM_001168468 NM_024791	PDZD3	PDZ domain containing 3
chr9_+_79968344	0.525		VPS13A	vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr12_+_70133179	0.519	NM_175623 NM_175625	RAB3IP	RAB3A interacting protein (rabin3)
chr11_-_8739398	0.515		ST5	suppression of tumorigenicity 5
chr22_+_45098046	0.510	NM_181333	PRR5	proline rich 5 (renal)
chr3_+_63953419	0.509	NM_001128149	ATXN7	ataxin 7
chr4_-_122854192	0.496	NM_003305	TRPC3	transient receptor potential cation channel, subfamily C, member 3
chr5_-_111093251	0.484	NM_001142479 NM_001142480 NM_001142478	C5orf13	chromosome 5 open reading frame 13
chr6_-_52668599	0.443	NM_145740	GSTA1	glutathione S-transferase alpha 1
chr19_+_11909360	0.410	NM_152356	ZNF491	zinc finger protein 491
chr16_-_66952729	0.401	NM_001204744 NM_001204745 NM_001204746 NM_004062	CDH16	cadherin 16, KSP-cadherin
chr9_-_215892	0.395	NM_152569	C9orf66	chromosome 9 open reading frame 66
chr22_-_38506532	0.386		BAIAP2L2	BAI1-associated protein 2-like 2
chr20_-_44538654	0.375		PLTP	phospholipid transfer protein
chr15_+_85923739	0.372	NM_006738 NM_007200	AKAP13	A kinase (PRKA) anchor protein 13
chr7_+_139528951	0.367	NM_001061 NM_001166253 NM_030984	TBXAS1	thromboxane A synthase 1 (platelet)
chr19_-_11639929	0.364	NM_001142464 NM_001142465 NM_016581	ECSIT	ECSIT homolog (Drosophila)
chrX_-_15332680	0.362	NM_001012428	ASB11	ankyrin repeat and SOCS box containing 11
chr12_+_121416294	0.357		HNF1A	HNF1 homeobox A
chr20_+_57414770	0.353		GNAS	GNAS complex locus
chr2_+_98330030	0.338	NM_001079	ZAP70	zeta-chain (TCR) associated protein kinase 70kDa
chr4_-_122148620	0.336	NM_001244764	TNIP3	TNFAIP3 interacting protein 3
chr3_+_149530436	0.332	NM_007282 NM_183381	RNF13	ring finger protein 13
chr3_+_100238063	0.329		TMEM45A	transmembrane protein 45A
chr14_+_55221505	0.317	NM_001161577	SAMD4A	sterile alpha motif domain containing 4A
chr8_-_133117511	0.299	NM_001145095	HHLA1	HERV-H LTR-associating 1
chr16_-_4896197	0.294		GLYR1	glyoxylate reductase 1 homolog (Arabidopsis)
chr20_+_57414794	0.286	NM_016592	GNAS	GNAS complex locus
chr7_-_107443631	0.285	NM_000111	SLC26A3	solute carrier family 26, member 3
chr21_-_34185943	0.280	NM_001162495 NM_001162496 NM_019596	C21orf62	chromosome 21 open reading frame 62
chr1_-_179833581	0.280
chr12_+_132434443	0.280	NM_015409	EP400	E1A binding protein p400
chr5_-_111091947	0.272	NM_001142483	C5orf13	chromosome 5 open reading frame 13
chrX_+_1710485	0.264	NM_005088	AKAP17A	A kinase (PRKA) anchor protein 17A
chrY_+_1660485	0.244	NM_005088	AKAP17A	A kinase (PRKA) anchor protein 17A
chr2_-_96482382	0.235		LINC00342	long intergenic non-protein coding RNA 342
chr12_+_21284127	0.229	NM_006446	SLCO1B1	solute carrier organic anion transporter family, member 1B1
chr2_+_102615456	0.223	NM_173343	IL1R2	interleukin 1 receptor, type II

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
52.27	1.61e-05	GO:0051917	regulation of fibrinolysis
16.44	1.97e-05	GO:0010951	negative regulation of endopeptidase activity
21.19	2.46e-05	GO:0030193	regulation of blood coagulation
19.64	4.29e-05	GO:0050818	regulation of coagulation
9.84	5.11e-05	GO:0051346	negative regulation of hydrolase activity
2.43	6.45e-05	GO:0065008	regulation of biological quality
24.65	9.64e-05	GO:0030195	negative regulation of blood coagulation
17.13	1.15e-04	GO:0061041	regulation of wound healing
23.80	1.21e-04	GO:0050819	negative regulation of coagulation
57.50	2.99e-04	GO:0051918	negative regulation of fibrinolysis
9.42	3.52e-04	GO:0030162	regulation of proteolysis
10.83	5.44e-04	GO:0010466	negative regulation of peptidase activity
13.42	6.45e-04	GO:0072376	protein activation cascade
7.20	9.59e-04	GO:0052548	regulation of endopeptidase activity
4.72	1.11e-03	GO:0071702	organic substance transport
6.89	1.42e-03	GO:0052547	regulation of peptidase activity
6.06	1.49e-03	GO:0008202	steroid metabolic process
4.56	1.67e-03	GO:0043086	negative regulation of catalytic activity
38.34	2.06e-03	GO:0030194	positive regulation of blood coagulation
3.11	3.76e-03	GO:0006629	lipid metabolic process
32.86	4.11e-03	GO:0050820	positive regulation of coagulation
3.92	4.49e-03	GO:0051336	regulation of hydrolase activity
16.92	8.29e-03	GO:0097006	regulation of plasma lipoprotein particle levels
11.90	8.41e-03	GO:0055088	lipid homeostasis
6.36	9.30e-03	GO:0006887	exocytosis
5.48	1.09e-02	GO:0032101	regulation of response to external stimulus
7.03	1.41e-02	GO:0006869	lipid transport
15.14	1.46e-02	GO:0030301	cholesterol transport
10.79	1.49e-02	GO:0006638	neutral lipid metabolic process
10.79	1.49e-02	GO:0006639	acylglycerol metabolic process
24.22	1.54e-02	GO:0034381	plasma lipoprotein particle clearance
3.74	1.63e-02	GO:0044092	negative regulation of molecular function
14.75	1.66e-02	GO:0015918	sterol transport
3.44	2.14e-02	GO:0042060	wound healing
21.91	2.35e-02	GO:0034367	macromolecular complex remodeling
21.91	2.35e-02	GO:0034368	protein-lipid complex remodeling
21.91	2.35e-02	GO:0034369	plasma lipoprotein particle remodeling
6.44	2.66e-02	GO:0010876	lipid localization
9.33	3.44e-02	GO:0002576	platelet degranulation
11.99	4.64e-02	GO:0033993	response to lipid
18.41	4.83e-02	GO:0071825	protein-lipid complex subunit organization
18.41	4.83e-02	GO:0071827	plasma lipoprotein particle organization

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
4.50	6.59e-09	GO:0005615	extracellular space
3.72	1.93e-07	GO:0044421	extracellular region part
2.75	2.22e-06	GO:0005576	extracellular region
15.49	3.94e-05	GO:0031983	vesicle lumen
14.69	4.01e-04	GO:0031093	platelet alpha granule lumen
14.38	4.55e-04	GO:0034774	secretory granule lumen
13.81	5.82e-04	GO:0060205	cytoplasmic membrane-bounded vesicle lumen
17.98	1.01e-03	GO:0032994	protein-lipid complex
17.98	1.01e-03	GO:0034358	plasma lipoprotein particle
12.33	1.14e-03	GO:0031091	platelet alpha granule
49.29	2.98e-03	GO:0005577	fibrinogen complex
20.91	4.75e-03	GO:0034364	high-density lipoprotein particle
4.95	2.81e-02	GO:0045177	apical part of cell
5.48	3.84e-02	GO:0016324	apical plasma membrane

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
14.85	9.58e-06	GO:0004867	serine-type endopeptidase inhibitor activity
9.17	9.43e-05	GO:0004866	endopeptidase inhibitor activity
9.01	1.10e-04	GO:0030414	peptidase inhibitor activity
8.78	1.36e-04	GO:0061135	endopeptidase regulator activity
5.71	5.71e-04	GO:0004857	enzyme inhibitor activity
7.25	6.80e-04	GO:0061134	peptidase regulator activity
13.38	5.74e-03	GO:0043498	cell surface binding
2.84	8.72e-03	GO:0030234	enzyme regulator activity
31.37	1.75e-02	GO:0034185	apolipoprotein binding
14.38	2.79e-02	GO:0005504	fatty acid binding