Motif ID: JUN.p2

Z-value: 1.295


Transcription factors associated with JUN.p2:

Gene SymbolEntrez IDGene Name
JUN 3725 jun oncogene
JUNB 3726 jun B proto-oncogene
JUND 3727 jun D proto-oncogene

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
JUNchr1_-_592496870.821.0e-04Click!
JUNBchr19_+_12902295-0.322.3e-01Click!
JUNDchr19_-_183920480.126.5e-01Click!


Activity profile for motif JUN.p2.

activity profile for motif JUN.p2


Sorted Z-values histogram for motif JUN.p2

Sorted Z-values for motif JUN.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of JUN.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_12695851 4.169 NM_021961
TEAD1
TEA domain family member 1 (SV40 transcriptional enhancer factor)
chr2_-_216300770 3.886 NM_002026
NM_054034
NM_212474
NM_212476
NM_212478
NM_212482
FN1





fibronectin 1





chr20_+_19915716 3.516 RIN2
Ras and Rab interactor 2
chr9_-_99382073 3.482 NM_003671
NM_033331
CDC14B

CDC14 cell division cycle 14 homolog B (S. cerevisiae)

chr1_-_20812727 3.191 NM_018584
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr19_+_16187266 2.970 TPM4
tropomyosin 4
chr19_+_16187315 2.938 TPM4
tropomyosin 4
chr3_-_99594915 2.657 NM_014890
FILIP1L
filamin A interacting protein 1-like
chr3_+_8543508 2.617 NM_014583
LMCD1
LIM and cysteine-rich domains 1
chr21_-_44846927 2.350 NM_173354
SIK1
salt-inducible kinase 1
chr11_+_117070039 2.344 NM_001001522
NM_003186
TAGLN

transgelin

chr6_+_139456240 2.299 NM_016217
HECA
headcase homolog (Drosophila)
chr2_-_238322770 2.149 COL6A3
collagen, type VI, alpha 3
chr19_+_16187306 2.118 TPM4
tropomyosin 4
chr2_-_238322840 2.066 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
COL6A3




collagen, type VI, alpha 3




chr4_-_186456580 1.993 NM_001114107
NM_014476
PDLIM3

PDZ and LIM domain 3

chr8_-_18666295 1.979 NM_206909
PSD3
pleckstrin and Sec7 domain containing 3
chr5_-_172198160 1.939 NM_004417
DUSP1
dual specificity phosphatase 1
chr3_+_8543539 1.920 LMCD1
LIM and cysteine-rich domains 1
chr11_+_69455938 1.841 CCND1
cyclin D1
chr11_+_69455837 1.840 NM_053056
CCND1
cyclin D1
chr4_-_111558150 1.839 PITX2
paired-like homeodomain 2
chr1_-_59249687 1.737 NM_002228
JUN
jun proto-oncogene
chr19_+_45349560 1.731 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr11_-_111782447 1.699 NM_001885
CRYAB
crystallin, alpha B
chr1_-_1293907 1.688 NM_032348
MXRA8
matrix-remodelling associated 8
chr2_-_216300444 1.687 FN1
fibronectin 1
chr3_+_187871473 1.661 NM_001167672
LPP
LIM domain containing preferred translocation partner in lipoma
chr2_-_238322815 1.660 COL6A3
collagen, type VI, alpha 3
chr7_+_134464417 1.631 CALD1
caldesmon 1
chr13_-_110802708 1.620 COL4A1
collagen, type IV, alpha 1
chr3_-_187463474 1.577 NM_001706
BCL6
B-cell CLL/lymphoma 6
chr1_+_99730067 1.567 LPPR4
lipid phosphate phosphatase-related protein type 4
chr21_+_47545189 1.547 COL6A2
collagen, type VI, alpha 2
chr10_+_63808968 1.545 NM_001244638
ARID5B
AT rich interactive domain 5B (MRF1-like)
chr17_+_41476351 1.524 NM_001661
ARL4D
ADP-ribosylation factor-like 4D
chr16_-_10674443 1.507 NM_001424
EMP2
epithelial membrane protein 2
chr6_+_39760148 1.468 NM_001201427
DAAM2
dishevelled associated activator of morphogenesis 2
chr21_+_47545896 1.444 COL6A2
collagen, type VI, alpha 2
chr8_-_42065037 1.437 PLAT
plasminogen activator, tissue
chr11_-_35547144 1.418 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr6_-_169653922 1.404 THBS2
thrombospondin 2
chr8_-_42065193 1.381 NM_000930
NM_033011
PLAT

plasminogen activator, tissue

chr19_-_52227220 1.369 NM_001523
HAS1
hyaluronan synthase 1
chr2_-_211168315 1.353 NM_079422
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr3_+_158991035 1.338 NM_001197107
NM_001197108
NM_014575
SCHIP1


schwannomin interacting protein 1


chr2_+_28615695 1.327 FOSL2
FOS-like antigen 2
chr2_+_220283098 1.327 NM_001927
DES
desmin
chr8_-_119123804 1.293 NM_000127
EXT1
exostosin 1
chr8_+_94929082 1.287 NM_018444
NM_001161780
NM_001161779
NM_001161781
PDP1



pyruvate dehyrogenase phosphatase catalytic subunit 1



chr11_+_129939807 1.269 APLP2
amyloid beta (A4) precursor-like protein 2
chr1_-_193155723 1.261 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr22_+_38597938 1.253 NM_001161572
NM_001161574
NM_012323
MAFF


v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)


chr5_-_57755787 1.251 NM_001252226
NM_006622
PLK2

polo-like kinase 2

chr3_+_100211554 1.227 TMEM45A
transmembrane protein 45A
chr10_-_99446899 1.220 NM_021732
AVPI1
arginine vasopressin-induced 1
chr11_+_129939792 1.214 APLP2
amyloid beta (A4) precursor-like protein 2
chr9_+_97488943 1.199 NM_001193331
NM_032823
C9orf3

chromosome 9 open reading frame 3

chr14_+_104095491 1.196 NM_001130107
NM_005552
NM_182923
KLC1


kinesin light chain 1


chr16_-_79634610 1.189 NM_001031804
NM_005360
MAF

v-maf musculoaponeurotic fibrosarcoma oncogene homolog (avian)

chr9_+_97488993 1.170 C9orf3
chromosome 9 open reading frame 3
chr12_+_13044352 1.168 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr10_-_62703822 1.168 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr4_-_111544206 1.161 NM_000325
PITX2
paired-like homeodomain 2
chr22_+_38598065 1.155 MAFF
v-maf musculoaponeurotic fibrosarcoma oncogene homolog F (avian)
chr3_+_62304667 1.134 C3orf14
chromosome 3 open reading frame 14
chr9_+_97521930 1.129 NM_001193329
C9orf3
chromosome 9 open reading frame 3
chr5_+_34687663 1.103 NM_001145523
RAI14
retinoic acid induced 14
chr11_+_69455978 1.098 CCND1
cyclin D1
chr2_+_241375030 1.088 NM_002081
GPC1
glypican 1
chr5_-_131562934 1.078 NM_001017973
NM_004199
P4HA2

prolyl 4-hydroxylase, alpha polypeptide II

chr7_+_65670256 1.070 NM_003596
TPST1
tyrosylprotein sulfotransferase 1
chrX_-_13835187 1.065 GPM6B
glycoprotein M6B
chr4_+_668250 1.065 MYL5
myosin, light chain 5, regulatory
chr11_+_129939847 1.061 APLP2
amyloid beta (A4) precursor-like protein 2
chr1_-_110933635 1.059 SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr2_-_86850935 1.054 RNF103
ring finger protein 103
chr2_+_232457574 1.050 NM_152614
C2orf57
chromosome 2 open reading frame 57
chr4_+_668312 1.041 MYL5
myosin, light chain 5, regulatory
chr19_-_9695166 1.034 NM_001008727
ZNF121
zinc finger protein 121
chr7_-_129592794 1.033 NM_003344
NM_182697
UBE2H

ubiquitin-conjugating enzyme E2H

chr11_+_129939787 1.031 APLP2
amyloid beta (A4) precursor-like protein 2
chr5_+_52776479 1.031 FST
follistatin
chr1_-_16482426 1.022 NM_004431
EPHA2
EPH receptor A2
chr17_+_66508564 1.020 PRKAR1A
protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)
chr12_+_13044493 1.020 GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr10_+_123923104 1.011 NM_006997
NM_206860
TACC2

transforming, acidic coiled-coil containing protein 2

chr10_+_102792166 1.005 SFXN3
sideroflexin 3
chr2_-_86850959 0.999 NM_001198951
NM_001198952
NM_005667
RNF103


ring finger protein 103


chr5_+_71403040 0.985 NM_005909
MAP1B
microtubule-associated protein 1B
chr2_+_5832778 0.981 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr16_+_31119748 0.972 BCKDK
branched chain ketoacid dehydrogenase kinase
chr8_-_18541441 0.967 PSD3
pleckstrin and Sec7 domain containing 3
chr5_+_71502700 0.963 MAP1B
microtubule-associated protein 1B
chr17_-_13505217 0.959 NM_006042
HS3ST3A1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1
chr6_-_128841432 0.947 NM_002844
NM_001135648
PTPRK

protein tyrosine phosphatase, receptor type, K

chr9_-_14086901 0.944 NFIB
nuclear factor I/B
chr1_-_110933683 0.939 NM_001201546
NM_001201547
NM_001201548
NM_001201549
NM_004696
SLC16A4




solute carrier family 16, member 4 (monocarboxylic acid transporter 5)




chr10_+_124134206 0.938 PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr16_+_86544104 0.935 NM_001451
FOXF1
forkhead box F1
chr16_+_31119730 0.933 BCKDK
branched chain ketoacid dehydrogenase kinase
chr10_+_123922940 0.929 TACC2
transforming, acidic coiled-coil containing protein 2
chr9_-_129884885 0.926 ANGPTL2
angiopoietin-like 2
chr12_-_102455793 0.925 NM_016053
CCDC53
coiled-coil domain containing 53
chr12_+_10365415 0.916 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr10_+_102792161 0.915 SFXN3
sideroflexin 3
chr14_+_88851987 0.915 NM_001040428
NM_018418
SPATA7

spermatogenesis associated 7

chrX_-_13956530 0.909 GPM6B
glycoprotein M6B
chr14_+_101292483 0.904


chr6_-_46293628 0.903 NM_005822
RCAN2
regulator of calcineurin 2
chr5_+_138211084 0.901 CTNNA1
catenin (cadherin-associated protein), alpha 1, 102kDa
chr18_-_21891469 0.896 NM_001242508
OSBPL1A
oxysterol binding protein-like 1A
chr13_+_48807492 0.889 ITM2B
integral membrane protein 2B
chr18_+_8717368 0.880 NM_015210
CCDC165
coiled-coil domain containing 165
chr22_-_44258210 0.879 NM_014351
SULT4A1
sulfotransferase family 4A, member 1
chr10_+_124134093 0.878 NM_001001974
PLEKHA1
pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr6_+_148663728 0.878 NM_015278
SASH1
SAM and SH3 domain containing 1
chr2_+_30454396 0.876 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr19_+_45349584 0.865 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr3_+_9975513 0.863 NM_015513
NM_001031717
NM_001077415
CRELD1


cysteine-rich with EGF-like domains 1


chr11_-_2159472 0.862 IGF2
insulin-like growth factor 2 (somatomedin A)
chr9_+_33624214 0.861 ANXA2P2
annexin A2 pseudogene 2
chrX_-_10645726 0.856 NM_001098624
MID1
midline 1 (Opitz/BBB syndrome)
chr6_+_148664124 0.855 SASH1
SAM and SH3 domain containing 1
chr6_+_148663953 0.853 SASH1
SAM and SH3 domain containing 1
chr12_+_54378929 0.851 NM_017409
HOXC10
homeobox C10
chr11_+_129939667 0.849 NM_001142276
NM_001142277
NM_001142278
NM_001642
APLP2



amyloid beta (A4) precursor-like protein 2



chr17_-_63822660 0.843 NM_001037325
CEP112
centrosomal protein 112kDa
chr8_-_98290072 0.842 TSPYL5
TSPY-like 5
chr7_-_129592711 0.841 NM_001202498
UBE2H
ubiquitin-conjugating enzyme E2H
chr3_+_171757432 0.839 FNDC3B
fibronectin type III domain containing 3B
chr3_-_187463227 0.835 BCL6
B-cell CLL/lymphoma 6
chr3_-_10067989 0.832 CIDECP
cell death-inducing DFFA-like effector c pseudogene
chr9_-_129884998 0.831 NM_012098
ANGPTL2
angiopoietin-like 2
chr15_-_35087748 0.818 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr12_+_122150638 0.816 NM_001080825
TMEM120B
transmembrane protein 120B
chr2_+_33172368 0.813 NM_206943
LTBP1
latent transforming growth factor beta binding protein 1
chr3_+_154797435 0.812 NM_000902
MME
membrane metallo-endopeptidase
chr1_-_235812994 0.803 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr12_-_102455763 0.799 CCDC53
coiled-coil domain containing 53
chr9_+_112887780 0.796 NM_001136562
AKAP2
A kinase (PRKA) anchor protein 2
chr11_-_63381907 0.794 NM_007069
PLA2G16
phospholipase A2, group XVI
chr21_-_45079327 0.788 NM_007031
HSF2BP
heat shock transcription factor 2 binding protein
chr8_+_98788014 0.774 LAPTM4B
lysosomal protein transmembrane 4 beta
chr11_-_63381840 0.768 PLA2G16
phospholipase A2, group XVI
chr21_+_47546427 0.764 COL6A2
collagen, type VI, alpha 2
chr1_+_78470593 0.764 NM_007034
DNAJB4
DnaJ (Hsp40) homolog, subfamily B, member 4
chr14_+_101292451 0.763 MEG3
maternally expressed 3 (non-protein coding)
chr1_+_99729847 0.762 NM_001166252
NM_014839
LPPR4

lipid phosphate phosphatase-related protein type 4

chr1_+_160175146 0.762 PEA15
phosphoprotein enriched in astrocytes 15
chr14_+_88852065 0.755 SPATA7
spermatogenesis associated 7
chr1_-_201475966 0.755 NM_001193571
CSRP1
cysteine and glycine-rich protein 1
chr1_-_201476241 0.749 CSRP1
cysteine and glycine-rich protein 1
chr11_-_119187811 0.747 NM_006500
MCAM
melanoma cell adhesion molecule
chrX_-_13956644 0.747 NM_001001994
GPM6B
glycoprotein M6B
chr6_-_46293404 0.742 RCAN2
regulator of calcineurin 2
chr1_-_201476218 0.739 CSRP1
cysteine and glycine-rich protein 1
chr8_+_26240522 0.738 NM_004331
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr3_+_11267666 0.737 NM_001098211
HRH1
histamine receptor H1
chr1_+_160175114 0.731 NM_003768
PEA15
phosphoprotein enriched in astrocytes 15
chr1_-_201476248 0.728 NM_001193570
NM_004078
CSRP1

cysteine and glycine-rich protein 1

chr11_+_69455884 0.723 CCND1
cyclin D1
chr1_-_95392501 0.720 NM_001839
CNN3
calponin 3, acidic
chr8_-_98290171 0.720 NM_033512
TSPYL5
TSPY-like 5
chr17_+_66508525 0.720 NM_002734
NM_212472
PRKAR1A

protein kinase, cAMP-dependent, regulatory, type I, alpha (tissue specific extinguisher 1)

chr11_-_63381940 0.713 NM_001128203
PLA2G16
phospholipase A2, group XVI
chr4_-_156297944 0.705 MAP9
microtubule-associated protein 9
chr9_+_34990266 0.705 NM_001135005
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr21_+_35190586 0.704 ITSN1
intersectin 1 (SH3 domain protein)
chr2_+_131862885 0.703 PLEKHB2
pleckstrin homology domain containing, family B (evectins) member 2
chr8_-_49833823 0.686 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chrX_-_68385249 0.678 NM_001032396
NM_022368
NM_145119
PJA1


praja ring finger 1


chr3_-_124774735 0.677 NM_020733
HEG1
HEG homolog 1 (zebrafish)
chr8_+_98787808 0.673 NM_018407
LAPTM4B
lysosomal protein transmembrane 4 beta
chr11_-_8832189 0.671 NM_213618
ST5
suppression of tumorigenicity 5
chr11_-_27723061 0.671 NM_170733
BDNF
brain-derived neurotrophic factor
chr12_+_56552141 0.664 MYL6
myosin, light chain 6, alkali, smooth muscle and non-muscle
chr3_-_107941168 0.662 NM_018010
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr2_+_54785453 0.661 NM_178313
SPTBN1
spectrin, beta, non-erythrocytic 1
chr4_-_170924911 0.654 NM_001009554
MFAP3L
microfibrillar-associated protein 3-like
chr1_+_25071906 0.653 CLIC4
chloride intracellular channel 4
chr2_+_28615668 0.651 FOSL2
FOS-like antigen 2
chr2_-_224467095 0.651 SCG2
secretogranin II
chr8_-_18871163 0.651 NM_015310
PSD3
pleckstrin and Sec7 domain containing 3
chr7_-_37956377 0.649 SFRP4
secreted frizzled-related protein 4
chr2_-_224467142 0.646 NM_003469
SCG2
secretogranin II
chrX_-_13835012 0.645 GPM6B
glycoprotein M6B
chr4_-_156297973 0.639 MAP9
microtubule-associated protein 9
chr12_-_102455739 0.638 CCDC53
coiled-coil domain containing 53
chr22_+_44319674 0.634 PNPLA3
patatin-like phospholipase domain containing 3
chr6_-_47277511 0.633 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr6_-_47277646 0.630 NM_014452
TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr13_-_52980628 0.629 NM_018676
NM_199263
THSD1

thrombospondin, type I, domain containing 1

chr17_+_53342356 0.625 HLF
hepatic leukemia factor
chr19_+_16187047 0.623 NM_003290
TPM4
tropomyosin 4
chr2_+_46524448 0.610 NM_001430
EPAS1
endothelial PAS domain protein 1
chr19_-_36246411 0.610 HSPB6
heat shock protein, alpha-crystallin-related, B6
chr19_-_46088084 0.609 NM_001017989
NM_025136
OPA3

optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)

chr6_-_47277354 0.600 TNFRSF21
tumor necrosis factor receptor superfamily, member 21
chr20_+_19870209 0.599 NM_018993
RIN2
Ras and Rab interactor 2

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
10.07 2.45e-03 GO:0043292 contractile fiber
9.22 1.81e-02 GO:0044449 contractile fiber part
8.96 2.07e-02 GO:0030016 myofibril

Nothing significant found in function category.