Motif ID: LHX3,4.p2

Z-value: 1.159


Transcription factors associated with LHX3,4.p2:

Gene SymbolEntrez IDGene Name
LHX3 8022 LIM homeobox 3
LHX4 89884 LIM homeobox 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
LHX3chr9_-_139094886,
chr9_-_139096954
-0.155.8e-01Click!


Activity profile for motif LHX3,4.p2.

activity profile for motif LHX3,4.p2


Sorted Z-values histogram for motif LHX3,4.p2

Sorted Z-values for motif LHX3,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LHX3,4.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_198608216 2.027 PTPRC
protein tyrosine phosphatase, receptor type, C
chr6_+_12717036 1.920 NM_001242648
NM_030948
PHACTR1

phosphatase and actin regulator 1

chr16_+_12058963 1.698 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr10_+_91152321 1.610 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr2_-_31352489 1.605 NM_001253827
GALNT14
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14 (GalNAc-T14)
chr1_-_197552304 1.591 DENND1B
DENN/MADD domain containing 1B
chr1_-_93342706 1.403 NM_001252271
FAM69A
family with sequence similarity 69, member A
chr14_-_106926393 1.245 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr3_-_57234279 1.230 NM_003865
HESX1
HESX homeobox 1
chr11_-_58343308 1.214 NM_004811
LPXN
leupaxin
chr7_-_25268057 1.186 NM_022150
NPVF
neuropeptide VF precursor
chr5_-_1882764 1.150 NM_016358
IRX4
iroquois homeobox 4
chr5_+_67586466 1.143 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr20_-_6104056 1.096 NM_017671
FERMT1
fermitin family member 1
chr11_+_22689653 1.019 NM_177553
GAS2
growth arrest-specific 2
chrX_-_13835012 1.005 GPM6B
glycoprotein M6B
chr13_-_99910548 0.927 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr1_+_198608136 0.880 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr6_-_29527701 0.877 NM_006398
UBD
ubiquitin D
chr1_+_198608244 0.851 PTPRC
protein tyrosine phosphatase, receptor type, C
chr2_-_158300517 0.842 NM_004288
CYTIP
cytohesin 1 interacting protein
chr2_-_175462428 0.838 WIPF1
WAS/WASL interacting protein family, member 1
chr8_-_110693233 0.813 NM_001099745
NM_001099746
SYBU

syntabulin (syntaxin-interacting)

chr12_-_102872329 0.809 NM_001111284
IGF1
insulin-like growth factor 1 (somatomedin C)
chr12_+_54410893 0.797 HOXC5
HOXC6
homeobox C5
homeobox C6
chr12_-_102512277 0.792 NM_024057
NUP37
nucleoporin 37kDa
chr5_-_88119604 0.789 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr8_-_110661007 0.782 NM_001099747
NM_001099748
NM_001099749
NM_001099750
NM_017786
SYBU




syntabulin (syntaxin-interacting)




chr12_-_102874299 0.776 IGF1
insulin-like growth factor 1 (somatomedin C)
chr5_+_67588395 0.771 NM_001242466
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr17_-_40833840 0.760 NM_016602
CCR10
chemokine (C-C motif) receptor 10
chr7_+_23286420 0.754 GPNMB
glycoprotein (transmembrane) nmb
chr1_-_150738232 0.749 CTSS
cathepsin S
chr3_-_151034514 0.738 NM_023915
GPR87
G protein-coupled receptor 87
chr12_+_28410132 0.735 NM_018318
CCDC91
coiled-coil domain containing 91
chr7_-_37024664 0.732 NM_001039459
ELMO1
engulfment and cell motility 1
chr8_+_54764367 0.728 NM_170587
RGS20
regulator of G-protein signaling 20
chr7_+_23286384 0.727 GPNMB
glycoprotein (transmembrane) nmb
chr10_+_48255223 0.715 NM_001040084
NM_001098845
ANXA8L2
ANXA8
ANXA8L1
annexin A8-like 2
annexin A8
annexin A8-like 1
chr13_-_36050758 0.707 NM_005584
MAB21L1
mab-21-like 1 (C. elegans)
chr3_+_63953419 0.679 NM_001128149
ATXN7
ataxin 7
chr10_-_47173917 0.674 NM_001040084
NM_001098845
ANXA8L2
ANXA8
ANXA8L1
annexin A8-like 2
annexin A8
annexin A8-like 1
chr7_+_129015483 0.674 NM_001130722
AHCYL2
adenosylhomocysteinase-like 2
chr7_+_23286390 0.668 GPNMB
glycoprotein (transmembrane) nmb
chr7_+_23286386 0.668 GPNMB
glycoprotein (transmembrane) nmb
chr5_+_115898218 0.652


chr10_+_47746919 0.649 NM_001630
ANXA8L2
ANXA8
annexin A8-like 2
annexin A8
chrX_+_37639246 0.630 NM_000397
CYBB
cytochrome b-245, beta polypeptide
chr8_+_98703361 0.605 MTDH
metadherin
chr8_-_102803196 0.601 NCALD
neurocalcin delta
chr7_-_7758237 0.594 NM_002947
RPA3
replication protein A3, 14kDa
chrX_-_72434623 0.591 NAP1L2
nucleosome assembly protein 1-like 2
chr9_+_118916069 0.573 NM_002581
PAPPA
pregnancy-associated plasma protein A, pappalysin 1
chr1_-_150738292 0.572 NM_001199739
NM_004079
CTSS

cathepsin S

chr20_-_18477811 0.571 NM_006606
RBBP9
retinoblastoma binding protein 9
chr6_-_33041266 0.570 NM_033554
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chrX_-_13835313 0.565 NM_001001995
NM_001001996
NM_005278
GPM6B


glycoprotein M6B


chr4_-_176733901 0.556 GPM6A
glycoprotein M6A
chr2_-_216003068 0.549 NM_173076
ABCA12
ATP-binding cassette, sub-family A (ABC1), member 12
chr3_-_126327397 0.548 NM_001039783
TXNRD3NB
thioredoxin reductase 3 neighbor
chr12_-_53600999 0.548 NM_000889
ITGB7
integrin, beta 7
chr12_-_53601051 0.542 ITGB7
integrin, beta 7
chr18_+_29027731 0.539 NM_001944
DSG3
desmoglein 3
chr14_+_67831484 0.531 EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr3_-_141747434 0.523 NM_001178141
NM_001178142
NM_006286
TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chrX_-_107682600 0.522 NM_001847
COL4A6
collagen, type IV, alpha 6
chr22_+_40297183 0.521 GRAP2
GRB2-related adaptor protein 2
chr1_-_114414245 0.521 NM_001193431
NM_012411
NM_015967
PTPN22


protein tyrosine phosphatase, non-receptor type 22 (lymphoid)


chrX_-_72434656 0.517 NAP1L2
nucleosome assembly protein 1-like 2
chrX_-_72434667 0.515 NM_021963
NAP1L2
nucleosome assembly protein 1-like 2
chr7_+_26400503 0.507 NM_001199837
SNX10
sorting nexin 10
chr11_-_115088628 0.500 CADM1
cell adhesion molecule 1
chr1_+_111413820 0.499 NM_001040033
CD53
CD53 molecule
chr8_-_102803178 0.496 NCALD
neurocalcin delta
chr7_+_77469446 0.486 NM_001127357
NM_001127359
NM_020432
PHTF2


putative homeodomain transcription factor 2


chr22_+_40297085 0.480 NM_004810
GRAP2
GRB2-related adaptor protein 2
chr12_-_102874373 0.479 NM_000618
NM_001111283
NM_001111285
IGF1


insulin-like growth factor 1 (somatomedin C)


chr14_-_106733392 0.476 IGHG1
IGHG3
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr1_+_168250277 0.469 NM_005149
TBX19
T-box 19
chr1_-_150738255 0.469 CTSS
cathepsin S
chr1_+_174844655 0.468 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr4_-_176733413 0.467 GPM6A
glycoprotein M6A
chrX_-_13835187 0.467 GPM6B
glycoprotein M6B
chr12_+_8332789 0.459 FAM66C
family with sequence similarity 66, member C
chr8_-_80993009 0.453 NM_001025252
TPD52
tumor protein D52
chr2_+_162272800 0.440 TBR1
T-box, brain, 1
chr14_-_106471439 0.439 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr12_-_102874321 0.438 IGF1
insulin-like growth factor 1 (somatomedin C)
chrX_-_110655384 0.436 NM_178151
NM_001195553
NM_178152
NM_178153
DCX



doublecortin



chr3_+_178276487 0.425 NM_005832
KCNMB2
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr4_-_103245468 0.425 NM_001135148
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr4_-_57547845 0.423 NM_001145460
NM_032495
NM_139212
HOPX


HOP homeobox


chr18_+_21269528 0.421 NM_001127717
NM_198129
LAMA3

laminin, alpha 3

chrX_+_99839789 0.415 NM_022144
TNMD
tenomodulin
chr6_-_169654047 0.415 NM_003247
THBS2
thrombospondin 2
chr2_+_162272892 0.414 TBR1
T-box, brain, 1
chr3_+_98250742 0.413 NM_005290
GPR15
G protein-coupled receptor 15
chr12_-_53994783 0.403 NM_001130059
ATF7
activating transcription factor 7
chr12_+_54422193 0.403 NM_004503
HOXC6
homeobox C6
chr14_-_107013474 0.399 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chrX_+_37639306 0.399 CYBB
cytochrome b-245, beta polypeptide
chr12_-_54653317 0.398 NM_001127322
CBX5
chromobox homolog 5
chr15_+_94899163 0.394 NM_001159644
MCTP2
multiple C2 domains, transmembrane 2
chr3_-_9291251 0.392 NM_001033117
NM_014850
SRGAP3

SLIT-ROBO Rho GTPase activating protein 3

chr20_-_52199635 0.391 NM_006526
ZNF217
zinc finger protein 217
chr11_-_102576444 0.377 NM_022122
MMP27
matrix metallopeptidase 27
chr12_-_102874340 0.377 IGF1
insulin-like growth factor 1 (somatomedin C)
chr3_-_141719188 0.377 NM_001178140
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr15_+_81489218 0.373 NM_001172128
IL16
interleukin 16
chr6_-_22297729 0.373 NM_000948
PRL
prolactin
chr6_-_136788012 0.372 NM_001198615
MAP7
microtubule-associated protein 7
chr5_-_22853435 0.371 CDH12
cadherin 12, type 2 (N-cadherin 2)
chr10_+_35426709 0.365 NM_183011
NM_183012
CREM

cAMP responsive element modulator

chr16_+_86612114 0.362 NM_005250
FOXL1
forkhead box L1
chr14_+_102276279 0.360 PPP2R5C
protein phosphatase 2, regulatory subunit B', gamma
chr15_+_34261088 0.359 NM_012125
CHRM5
cholinergic receptor, muscarinic 5
chrX_+_24073071 0.357 EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr12_-_54653369 0.356 NM_001127321
CBX5
chromobox homolog 5
chrX_+_70765479 0.354 OGT
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr2_-_122159140 0.354 CLASP1
cytoplasmic linker associated protein 1
chr2_+_68961912 0.353 NM_001007231
NM_001166277
ARHGAP25

Rho GTPase activating protein 25

chr12_-_102874158 0.351 IGF1
insulin-like growth factor 1 (somatomedin C)
chr1_+_100316530 0.350 NM_000646
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr8_-_29207795 0.347 NM_001394
DUSP4
dual specificity phosphatase 4
chr1_-_92952429 0.345 NM_005263
GFI1
growth factor independent 1 transcription repressor
chr6_-_87804773 0.345 NM_000735
NM_001252383
CGA

glycoprotein hormones, alpha polypeptide

chr20_-_7921068 0.339 NM_017545
HAO1
hydroxyacid oxidase (glycolate oxidase) 1
chr2_-_216946463 0.337 NM_018441
PECR
peroxisomal trans-2-enoyl-CoA reductase
chr7_+_23286277 0.336 NM_001005340
NM_002510
GPNMB

glycoprotein (transmembrane) nmb

chr3_+_130569368 0.335 NM_001199180
NM_001199181
NM_001199182
ATP2C1


ATPase, Ca++ transporting, type 2C, member 1


chr13_+_24463006 0.330 NM_001014442
C1QTNF9B-AS1
C1QTNF9B antisense RNA 1 (non-protein coding)
chr8_+_132991171 0.326 EFR3A
EFR3 homolog A (S. cerevisiae)
chr4_-_116034932 0.323 NM_022569
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr8_-_102803438 0.321 NM_032041
NCALD
neurocalcin delta
chr3_-_79817058 0.317 NM_002941
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr2_+_234637772 0.316 NM_019093
UGT1A3
UDP glucuronosyltransferase 1 family, polypeptide A3
chr2_+_162272619 0.315 NM_006593
TBR1
T-box, brain, 1
chr3_+_141043054 0.313 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chrX_+_107288199 0.311 NM_001170553
NM_182607
VSIG1

V-set and immunoglobulin domain containing 1

chr12_-_26277807 0.307 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr1_+_158801105 0.306 NM_002432
MNDA
myeloid cell nuclear differentiation antigen
chr6_+_73076431 0.301 NM_001168411
RIMS1
regulating synaptic membrane exocytosis 1
chr11_+_99426872 0.300 NM_175566
CNTN5
contactin 5
chr6_-_24877453 0.300 NM_015864
FAM65B
family with sequence similarity 65, member B
chr14_-_106539099 0.300 IGHA1
IGHG1
IGHG3
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr6_-_32908583 0.299 NM_002118
HLA-DMB
major histocompatibility complex, class II, DM beta
chr3_+_69812961 0.294 NM_006722
MITF
microphthalmia-associated transcription factor
chr4_-_76944585 0.292 NM_001565
CXCL10
chemokine (C-X-C motif) ligand 10
chr1_+_79115476 0.288 NM_006417
IFI44
interferon-induced protein 44
chr4_-_120243257 0.286 NM_000134
FABP2
fatty acid binding protein 2, intestinal
chr2_-_200213802 0.285 SATB2
SATB homeobox 2
chr10_+_18549583 0.284 NM_000724
CACNB2
calcium channel, voltage-dependent, beta 2 subunit
chr13_-_41593405 0.282 ELF1
E74-like factor 1 (ets domain transcription factor)
chr3_+_142342265 0.281 NM_002670
PLS1
plastin 1
chr3_-_124930192 0.277 NM_001195483
SLC12A8
solute carrier family 12 (potassium/chloride transporters), member 8
chr3_-_167191808 0.277 NM_006217
SERPINI2
serpin peptidase inhibitor, clade I (pancpin), member 2
chr3_-_119582422 0.274 GSK3B
glycogen synthase kinase 3 beta
chr3_-_105421044 0.274 CBLB
Cas-Br-M (murine) ecotropic retroviral transforming sequence b
chr12_+_25205488 0.274 LRMP
lymphoid-restricted membrane protein
chrX_+_24073060 0.273 NM_001415
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr8_-_57026540 0.272 NM_005372
MOS
v-mos Moloney murine sarcoma viral oncogene homolog
chr18_+_29769986 0.271 NM_005925
MEP1B
meprin A, beta
chr7_+_28452143 0.271 NM_182898
CREB5
cAMP responsive element binding protein 5
chr2_+_102979096 0.270 NM_003855
IL18R1
interleukin 18 receptor 1
chr1_+_159259503 0.268 NM_002001
FCER1A
Fc fragment of IgE, high affinity I, receptor for; alpha polypeptide
chr17_-_39092714 0.268 KRT23
keratin 23 (histone deacetylase inducible)
chr12_+_14538232 0.268 ATF7IP
activating transcription factor 7 interacting protein
chr4_+_88571453 0.267 NM_001079911
NM_004407
DMP1

dentin matrix acidic phosphoprotein 1

chr7_-_27166638 0.263 NM_153631
HOXA3
homeobox A3
chr7_+_90339146 0.263 CDK14
cyclin-dependent kinase 14
chrX_-_24690740 0.262 NM_001163264
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr5_+_156696351 0.255 NM_014376
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr12_-_46633551 0.254 SLC38A1
solute carrier family 38, member 1
chr14_+_102276125 0.254 NM_002719
NM_178586
NM_178587
PPP2R5C


protein phosphatase 2, regulatory subunit B', gamma


chr6_+_31583766 0.254 NM_032955
AIF1
allograft inflammatory factor 1
chr18_-_3845295 0.251 NM_001003809
NM_001242765
NM_001242766
DLGAP1


discs, large (Drosophila) homolog-associated protein 1


chr4_-_46911223 0.250 NM_130902
COX7B2
cytochrome c oxidase subunit VIIb2
chr9_-_112191105 0.249 NM_001145371
NM_001145372
PTPN3

protein tyrosine phosphatase, non-receptor type 3

chr7_+_96745904 0.247 NM_020186
ACN9
ACN9 homolog (S. cerevisiae)
chr12_-_10282680 0.242 NM_022570
NM_197947
NM_197948
NM_197949
NM_197950
NM_197954
CLEC7A





C-type lectin domain family 7, member A





chr8_+_22844918 0.236 NM_001160036
RHOBTB2
Rho-related BTB domain containing 2
chr3_-_12941547 0.235 IQSEC1
IQ motif and Sec7 domain 1
chr14_-_64194692 0.235 NM_030791
SGPP1
sphingosine-1-phosphate phosphatase 1
chr8_-_101315457 0.234 NM_015435
RNF19A
ring finger protein 19A
chr1_+_153003677 0.234 NM_003125
SPRR1B
small proline-rich protein 1B
chrX_+_49091926 0.234 NM_014008
CCDC22
coiled-coil domain containing 22
chr21_-_31538970 0.233 NM_012131
CLDN17
claudin 17
chr9_+_12693385 0.230 NM_000550
TYRP1
tyrosinase-related protein 1
chr2_-_191872322 0.229 STAT1
signal transducer and activator of transcription 1, 91kDa
chr5_+_59784004 0.228 PART1
prostate androgen-regulated transcript 1 (non-protein coding)
chr15_+_52201590 0.228 TMOD3
tropomodulin 3 (ubiquitous)
chr7_-_122839999 0.227 NM_022444
SLC13A1
solute carrier family 13 (sodium/sulfate symporters), member 1
chr3_+_119316694 0.226 NM_001206960
NM_001206961
NM_015900
PLA1A


phospholipase A1 member A


chrX_-_114252132 0.225 NM_000640
IL13RA2
interleukin 13 receptor, alpha 2
chrX_-_118726852 0.225 NM_001173488
NKRF
NFKB repressing factor
chr1_-_154578775 0.224 NM_001193495
ADAR
adenosine deaminase, RNA-specific
chr17_-_39093671 0.222 NM_015515
KRT23
keratin 23 (histone deacetylase inducible)
chr3_+_39424766 0.218 NM_017875
SLC25A38
solute carrier family 25, member 38
chr20_-_34025955 0.217 NM_000557
GDF5
growth differentiation factor 5
chr3_-_111314181 0.217 NM_024508
ZBED2
zinc finger, BED-type containing 2

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.