Motif ID: MYBL2.p2

Z-value: 1.207


Transcription factors associated with MYBL2.p2:

Gene SymbolEntrez IDGene Name
MYBL2 4605 v-myb myeloblastosis viral oncogene homolog (avian)-like 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MYBL2chr20_+_42295747-0.381.5e-01Click!


Activity profile for motif MYBL2.p2.

activity profile for motif MYBL2.p2


Sorted Z-values histogram for motif MYBL2.p2

Sorted Z-values for motif MYBL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of MYBL2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_157154579 6.587 NM_002852
PTX3
pentraxin 3, long
chr10_+_17270257 5.336 NM_003380
VIM
vimentin
chr10_+_17270469 3.676 VIM
vimentin
chr2_-_190044330 3.011 NM_000393
COL5A2
collagen, type V, alpha 2
chr12_+_78225068 2.969 NM_014903
NAV3
neuron navigator 3
chr3_-_123339178 2.952 MYLK
myosin light chain kinase
chr5_-_39425030 2.763 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr5_-_39424930 2.681 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr5_-_39425297 2.248 NM_001244871
NM_001343
DAB2

disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)

chr2_+_170366211 2.197 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr9_+_116356199 2.193 NM_144489
RGS3
regulator of G-protein signaling 3
chrX_+_135278912 1.964 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr17_-_48264039 1.927 COL1A1
collagen, type I, alpha 1
chr9_+_116356407 1.833 RGS3
regulator of G-protein signaling 3
chr1_-_193155723 1.814 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr3_-_123339423 1.799 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr9_+_79056581 1.745 NM_001097634
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr11_-_119294242 1.725 NM_006288
THY1
Thy-1 cell surface antigen
chr11_-_111782447 1.556 NM_001885
CRYAB
crystallin, alpha B
chr2_+_231281470 1.531 NM_001206704
SP100
SP100 nuclear antigen
chr9_-_14086901 1.486 NFIB
nuclear factor I/B
chr2_+_152214105 1.474 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr1_+_84630374 1.454 PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr21_+_30517897 1.452 C21orf7
chromosome 21 open reading frame 7
chr1_+_84630014 1.443 NM_001242857
NM_001242858
NM_001242859
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr15_+_43809805 1.426 NM_002373
MAP1A
microtubule-associated protein 1A
chr13_+_102104941 1.307 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr4_-_111563278 1.160 NM_001204397
NM_001204398
NM_001204399
NM_153426
NM_153427
PITX2




paired-like homeodomain 2




chr17_-_15554809 1.154 TRIM16
tripartite motif containing 16
chr3_+_8775485 1.142 NM_001234
NM_033337
CAV3

caveolin 3

chr20_+_19915716 1.127 RIN2
Ras and Rab interactor 2
chr5_-_94417185 1.127 MCTP1
multiple C2 domains, transmembrane 1
chr1_+_174844655 1.102 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr10_-_121296044 1.095 NM_002925
RGS10
regulator of G-protein signaling 10
chr21_+_37507209 1.069 NM_001236
CBR3
carbonyl reductase 3
chr20_+_9288446 1.051 NM_000933
PLCB4
phospholipase C, beta 4
chr3_-_114478117 1.037 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr5_+_155754172 1.020 SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr2_-_152590983 1.004 NM_001164507
NM_001164508
NM_004543
NEB


nebulin


chr3_-_15839674 0.983 NM_001195098
ANKRD28
ankyrin repeat domain 28
chr5_-_94417544 0.983 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr1_-_103496768 0.978 COL11A1
collagen, type XI, alpha 1
chr12_+_56915587 0.973 NM_002898
RBMS2
RNA binding motif, single stranded interacting protein 2
chr12_+_13043955 0.972 NM_003979
GPRC5A
G protein-coupled receptor, family C, group 5, member A
chr3_+_35721115 0.965 NM_001025068
NM_001025069
ARPP21

cAMP-regulated phosphoprotein, 21kDa

chr10_-_70092648 0.964 NM_001033083
NM_022129
PBLD

phenazine biosynthesis-like protein domain containing

chr11_+_124543739 0.960 NM_017425
SPA17
sperm autoantigenic protein 17
chr18_-_21891469 0.950 NM_001242508
OSBPL1A
oxysterol binding protein-like 1A
chr9_-_95298251 0.940 NM_001197295
NM_001197296
NM_001393
ECM2


extracellular matrix protein 2, female organ and adipocyte specific


chr1_-_150780705 0.857 NM_000396
CTSK
cathepsin K
chrX_-_10588458 0.853 NM_000381
NM_033289
MID1

midline 1 (Opitz/BBB syndrome)

chr4_+_148402068 0.851 NM_001166055
NM_001957
EDNRA

endothelin receptor type A

chr12_-_50616425 0.840 NM_001113547
LIMA1
LIM domain and actin binding 1
chr6_+_151561094 0.828 NM_005100
AKAP12
A kinase (PRKA) anchor protein 12
chr11_+_131240370 0.823 NM_001048209
NTM
neurotrimin
chrX_+_80457302 0.798 NM_003022
SH3BGRL
SH3 domain binding glutamic acid-rich protein like
chr8_-_95274520 0.784 GEM
GTP binding protein overexpressed in skeletal muscle
chr3_+_135684463 0.782 NM_001190447
NM_002718
PPP2R3A

protein phosphatase 2, regulatory subunit B'', alpha

chrX_+_149613719 0.750 NM_001177466
NM_005491
MAMLD1

mastermind-like domain containing 1

chr19_+_48828627 0.748 NM_001425
EMP3
epithelial membrane protein 3
chr1_+_148577356 0.742 NM_001102663
NBPF15
NBPF16
neuroblastoma breakpoint family, member 15
neuroblastoma breakpoint family, member 16
chr15_+_67418053 0.731 NM_001145102
SMAD3
SMAD family member 3
chr10_-_98031154 0.718 NM_001114094
NM_013314
BLNK

B-cell linker

chr3_+_141043054 0.716 NM_001080412
ZBTB38
zinc finger and BTB domain containing 38
chr4_+_148402117 0.716 EDNRA
endothelin receptor type A
chr5_+_155753755 0.701 NM_000337
NM_001128209
NM_172244
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr2_+_231280870 0.699 NM_001080391
NM_001206701
NM_001206702
NM_001206703
NM_003113
SP100




SP100 nuclear antigen




chr1_-_93342706 0.657 NM_001252271
FAM69A
family with sequence similarity 69, member A
chr12_+_54422193 0.635 NM_004503
HOXC6
homeobox C6
chr4_+_120056938 0.633 NM_016599
MYOZ2
myozenin 2
chr1_-_197036350 0.630 NM_001994
F13B
coagulation factor XIII, B polypeptide
chr9_-_14398981 0.629 NM_001190738
NFIB
nuclear factor I/B
chr2_+_231280906 0.622 SP100
SP100 nuclear antigen
chr19_+_48828820 0.611 EMP3
epithelial membrane protein 3
chr20_-_52687303 0.611 NM_003657
BCAS1
breast carcinoma amplified sequence 1
chr3_-_127541160 0.609 NM_007283
MGLL
monoglyceride lipase
chr22_+_38071612 0.595 NM_002305
LGALS1
lectin, galactoside-binding, soluble, 1
chr17_-_42908178 0.587 NM_001080383
GJC1
gap junction protein, gamma 1, 45kDa
chr5_-_54281345 0.584 NM_001135604
NM_007036
ESM1

endothelial cell-specific molecule 1

chr1_-_9129620 0.574 SLC2A5
solute carrier family 2 (facilitated glucose/fructose transporter), member 5
chr3_-_27498244 0.571 NM_003615
SLC4A7
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr5_-_157002739 0.570 NM_033274
ADAM19
ADAM metallopeptidase domain 19
chr16_+_12058963 0.556 NM_001192
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr1_+_163038395 0.552 NM_001102445
RGS4
regulator of G-protein signaling 4
chr3_+_33318911 0.552 NM_012157
NM_001171713
FBXL2

F-box and leucine-rich repeat protein 2

chr6_-_112080284 0.551 NM_153048
FYN
FYN oncogene related to SRC, FGR, YES
chr14_-_23288912 0.551 NM_001126106
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr1_+_144614958 0.551 NM_001037675
NBPF9
NBPF8
neuroblastoma breakpoint family, member 9
neuroblastoma breakpoint family, member 8
chr1_-_110933635 0.547 SLC16A4
solute carrier family 16, member 4 (monocarboxylic acid transporter 5)
chr12_-_91576805 0.544 NM_001920
DCN
decorin
chr7_-_81399286 0.543 NM_000601
NM_001010931
NM_001010932
NM_001010933
NM_001010934
HGF




hepatocyte growth factor (hepapoietin A; scatter factor)




chr10_-_92680784 0.540 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr15_-_72563627 0.534 NM_020214
PARP6
poly (ADP-ribose) polymerase family, member 6
chr1_-_115300583 0.518 CSDE1
cold shock domain containing E1, RNA-binding
chr8_-_95274540 0.513 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr2_-_211168315 0.512 NM_079422
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr1_-_9129666 0.511 NM_001135585
NM_003039
SLC2A5

solute carrier family 2 (facilitated glucose/fructose transporter), member 5

chr12_-_15114495 0.507 NM_001175
ARHGDIB
Rho GDP dissociation inhibitor (GDI) beta
chr1_-_115300601 0.507 CSDE1
cold shock domain containing E1, RNA-binding
chr15_+_49715374 0.506 NM_002009
FGF7
fibroblast growth factor 7
chr6_-_24877453 0.503 NM_015864
FAM65B
family with sequence similarity 65, member B
chrX_-_21776158 0.502 NM_014332
SMPX
small muscle protein, X-linked
chrX_-_106960268 0.499 NM_004089
TSC22D3
TSC22 domain family, member 3
chr1_-_115300561 0.490 CSDE1
cold shock domain containing E1, RNA-binding
chr15_-_42749710 0.486 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr11_-_104827421 0.486 NM_033306
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr1_-_110933683 0.478 NM_001201546
NM_001201547
NM_001201548
NM_001201549
NM_004696
SLC16A4




solute carrier family 16, member 4 (monocarboxylic acid transporter 5)




chr15_+_63334753 0.474 NM_000366
NM_001018004
NM_001018005
NM_001018006
NM_001018007
NM_001018020
TPM1





tropomyosin 1 (alpha)





chr12_-_16757944 0.472 LMO3
LIM domain only 3 (rhombotin-like 2)
chr21_-_27253197 0.472 APP
amyloid beta (A4) precursor protein
chr1_+_218518675 0.468 NM_001135599
NM_003238
TGFB2

transforming growth factor, beta 2

chr17_-_58603492 0.468 NM_006380
APPBP2
amyloid beta precursor protein (cytoplasmic tail) binding protein 2
chr1_-_115300586 0.445 CSDE1
cold shock domain containing E1, RNA-binding
chrX_-_114252132 0.444 NM_000640
IL13RA2
interleukin 13 receptor, alpha 2
chr20_-_52687014 0.440 BCAS1
breast carcinoma amplified sequence 1
chr17_+_42634598 0.439 NM_001466
FZD2
frizzled family receptor 2
chr10_-_90750955 0.438 NM_001141945
ACTA2
actin, alpha 2, smooth muscle, aorta
chr3_-_126327397 0.434 NM_001039783
TXNRD3NB
thioredoxin reductase 3 neighbor
chr1_-_154943001 0.431 NM_001130040
NM_183001
SHC1

SHC (Src homology 2 domain containing) transforming protein 1

chrX_+_12885190 0.431 NM_016562
TLR7
toll-like receptor 7
chr2_+_231280933 0.424 SP100
SP100 nuclear antigen
chr11_+_33563772 0.423 NM_012194
C11orf41
chromosome 11 open reading frame 41
chr12_+_14538232 0.418 ATF7IP
activating transcription factor 7 interacting protein
chr2_-_224467142 0.408 NM_003469
SCG2
secretogranin II
chr14_-_89016806 0.398 PTPN21
protein tyrosine phosphatase, non-receptor type 21
chr1_+_155853546 0.396 SYT11
synaptotagmin XI
chr13_-_37679800 0.395 NM_145203
CSNK1A1L
casein kinase 1, alpha 1-like
chr12_-_57505176 0.391 NM_001178078
NM_001178080
NM_001178081
NM_003153
STAT6



signal transducer and activator of transcription 6, interleukin-4 induced



chr6_-_117747017 0.391 NM_002944
ROS1
c-ros oncogene 1 , receptor tyrosine kinase
chr2_+_228356287 0.391 AGFG1
ArfGAP with FG repeats 1
chr4_+_148402244 0.391 EDNRA
endothelin receptor type A
chr22_+_44395090 0.389 NM_001003828
PARVB
parvin, beta
chr1_-_116311398 0.386 NM_001232
CASQ2
calsequestrin 2 (cardiac muscle)
chr7_+_80267972 0.381 CD36
CD36 molecule (thrombospondin receptor)
chr11_-_27742224 0.378 NM_001143805
NM_001143806
NM_170732
BDNF


brain-derived neurotrophic factor


chr12_-_50677238 0.375 NM_001113546
NM_016357
LIMA1

LIM domain and actin binding 1

chr8_+_94929991 0.372 NM_001161778
PDP1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr3_+_150321065 0.371 NM_016275
SELT
selenoprotein T
chr6_-_131321868 0.369 NM_001252660
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr12_-_57505121 0.369 STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr1_-_201390845 0.365 NM_003281
TNNI1
troponin I type 1 (skeletal, slow)
chr10_-_92681025 0.362 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr21_-_30257611 0.361 NM_013240
NM_182749
N6AMT1

N-6 adenine-specific DNA methyltransferase 1 (putative)

chr1_+_84630575 0.357 NM_001242860
NM_001242861
PRKACB

protein kinase, cAMP-dependent, catalytic, beta

chr12_+_20963637 0.348 NM_019844
SLCO1B3
solute carrier organic anion transporter family, member 1B3
chr1_-_163172624 0.346 NM_001195303
RGS5
regulator of G-protein signaling 5
chr14_+_59104736 0.340 NM_001079520
NM_016651
DACT1

dapper, antagonist of beta-catenin, homolog 1 (Xenopus laevis)

chr3_-_114790221 0.331 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr17_-_46035109 0.331 NM_024320
PRR15L
proline rich 15-like
chr2_-_224467049 0.331 SCG2
secretogranin II
chrX_-_101771641 0.331 NM_021992
TMSB15A
TMSB15B
thymosin beta 15a
thymosin beta 15B
chr8_+_22437983 0.328 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr6_+_153019029 0.322 NM_025107
MYCT1
myc target 1
chr21_-_27423423 0.321


chr1_-_116311161 0.319 CASQ2
calsequestrin 2 (cardiac muscle)
chr9_+_120466625 0.315 TLR4
toll-like receptor 4
chr2_+_237478379 0.315 NM_020311
CXCR7
chemokine (C-X-C motif) receptor 7
chr2_+_33701678 0.310 RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr7_+_80267922 0.307 CD36
CD36 molecule (thrombospondin receptor)
chr2_-_190627923 0.304 NM_022353
OSGEPL1
O-sialoglycoprotein endopeptidase-like 1
chr10_-_28571014 0.302 NM_173496
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr12_-_26277807 0.300 NM_030762
BHLHE41
basic helix-loop-helix family, member e41
chr12_-_71031174 0.295 NM_001109754
PTPRB
protein tyrosine phosphatase, receptor type, B
chr4_-_120549115 0.294 NM_033437
PDE5A
phosphodiesterase 5A, cGMP-specific
chr4_+_113970784 0.293 NM_001148
NM_020977
ANK2

ankyrin 2, neuronal

chr2_-_224467095 0.292 SCG2
secretogranin II
chr9_+_120466453 0.289 NM_138554
TLR4
toll-like receptor 4
chr3_+_16974581 0.285 NM_015184
PLCL2
phospholipase C-like 2
chr13_+_76334796 0.282 NM_015842
LMO7
LIM domain 7
chr1_-_115300615 0.281 NM_001007553
NM_001130523
NM_001242891
NM_001242892
NM_001242893
NM_007158
CSDE1





cold shock domain containing E1, RNA-binding





chr5_+_42548314 0.277 NM_001242403
GHR
growth hormone receptor
chr12_-_57504935 0.276 STAT6
signal transducer and activator of transcription 6, interleukin-4 induced
chr8_-_122653493 0.275 NM_005328
HAS2
hyaluronan synthase 2
chr14_-_75600111 0.275 TMED10
transmembrane emp24-like trafficking protein 10 (yeast)
chr20_+_9494995 0.269 NM_001199897
NM_012261
LAMP5

lysosomal-associated membrane protein family, member 5

chr9_-_16727887 0.268 BNC2
basonuclin 2
chr2_+_37571752 0.264 NM_012413
QPCT
glutaminyl-peptide cyclotransferase
chr15_+_68871285 0.261 NM_006091
CORO2B
coronin, actin binding protein, 2B
chr18_+_72922725 0.256 NM_005786
TSHZ1
teashirt zinc finger homeobox 1
chr1_+_148739441 0.252 NM_001102663
NBPF15
NBPF8
NBPF16
neuroblastoma breakpoint family, member 15
neuroblastoma breakpoint family, member 8
neuroblastoma breakpoint family, member 16
chr6_-_112041253 0.252 NM_153047
FYN
FYN oncogene related to SRC, FGR, YES
chr4_+_77953942 0.251 SEPT11
septin 11
chr17_-_1303548 0.250 NM_006761
YWHAE
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon polypeptide
chr19_+_41509825 0.249 CYP2B6
cytochrome P450, family 2, subfamily B, polypeptide 6
chrX_+_102883891 0.248 NM_001006639
NM_004780
TCEAL1

transcription elongation factor A (SII)-like 1

chr8_+_26150731 0.248 NM_001177591
PPP2R2A
protein phosphatase 2, regulatory subunit B, alpha
chr11_-_102401430 0.247 NM_002423
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr3_+_113616317 0.245 NM_001172105
GRAMD1C
GRAM domain containing 1C
chr5_+_36606667 0.245 SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrX_+_51546154 0.243 NM_001005332
MAGED1
melanoma antigen family D, 1
chr11_+_101983170 0.236 NM_001195045
YAP1
Yes-associated protein 1
chr10_+_99332197 0.235 NM_001129981
NM_020349
ANKRD2

ankyrin repeat domain 2 (stretch responsive muscle)

chrX_+_114827818 0.235 NM_001136025
NM_001172335
PLS3

plastin 3

chr1_-_116311330 0.234 CASQ2
calsequestrin 2 (cardiac muscle)
chr10_-_98325100 0.233 TM9SF3
transmembrane 9 superfamily member 3
chr1_+_101185195 0.231 NM_001078
NM_001199834
NM_080682
VCAM1


vascular cell adhesion molecule 1


chr5_+_36608430 0.230 NM_001166695
SLC1A3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_+_23305792 0.230 NM_004995
MMP14
matrix metallopeptidase 14 (membrane-inserted)
chr11_+_128563993 0.229 FLI1
Friend leukemia virus integration 1
chr2_+_33738941 0.229 NM_015376
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
69.72 2.39e-02 GO:0005583 fibrillar collagen

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
9.71 7.80e-03 GO:0005096 GTPase activator activity
5.33 1.37e-02 GO:0005198 structural molecule activity