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• Activity deltas table
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Motif ID: NFATC1..3.p2

Z-value: 1.596

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_+_13349720	9.762		EMP1	epithelial membrane protein 1
chr12_+_13349601	8.655	NM_001423	EMP1	epithelial membrane protein 1
chr2_+_189839132	6.097		COL3A1	collagen, type III, alpha 1
chr2_+_189839078	5.266	NM_000090	COL3A1	collagen, type III, alpha 1
chr2_-_238322840	5.228	NM_004369 NM_057164 NM_057165 NM_057166 NM_057167	COL6A3	collagen, type VI, alpha 3
chr2_-_238322770	5.128		COL6A3	collagen, type VI, alpha 3
chr2_+_189839113	5.065		COL3A1	collagen, type III, alpha 1
chr2_-_238322815	4.692		COL6A3	collagen, type VI, alpha 3
chr4_+_169418167	4.537	NM_001166108 NM_016081	PALLD	palladin, cytoskeletal associated protein
chr18_-_21891469	4.289	NM_001242508	OSBPL1A	oxysterol binding protein-like 1A
chr3_+_159557745	4.272		SCHIP1	schwannomin interacting protein 1
chr6_-_128841432	3.664	NM_002844 NM_001135648	PTPRK	protein tyrosine phosphatase, receptor type, K
chr7_+_116164838	3.616	NM_001753	CAV1	caveolin 1, caveolae protein, 22kDa
chr12_-_91573264	3.598	NM_133503	DCN	decorin
chr22_-_36236264	3.440		RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr6_-_169654047	3.430	NM_003247	THBS2	thrombospondin 2
chr22_-_36236421	3.135	NM_001031695 NM_001082576 NM_001082577 NM_014309	RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr22_-_36236330	3.118		RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr1_+_158979681	3.097	NM_001206567 NM_005531	IFI16	interferon, gamma-inducible protein 16
chr1_-_150780705	3.053	NM_000396	CTSK	cathepsin K
chr6_-_169653922	2.769		THBS2	thrombospondin 2
chrX_-_10544852	2.705	NM_001193277	MID1	midline 1 (Opitz/BBB syndrome)
chr1_+_99127146	2.700	NM_015976 NM_152238	SNX7	sorting nexin 7
chr2_-_216259197	2.651		FN1	fibronectin 1
chr15_+_25101697	2.557	NM_022805	SNRPN	small nuclear ribonucleoprotein polypeptide N
chr1_+_86046434	2.402	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr16_-_65155881	2.377	NM_001797	CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)
chr6_-_134639195	2.372	NM_001143676	SGK1	serum/glucocorticoid regulated kinase 1
chr20_+_19915716	2.292		RIN2	Ras and Rab interactor 2
chr1_-_68697997	2.286	NM_001002292 NM_001193334 NM_024911	WLS	wntless homolog (Drosophila)
chrX_+_100805415	2.277	NM_016608	ARMCX1	armadillo repeat containing, X-linked 1
chr3_+_187943192	2.274	NM_001167671	LPP	LIM domain containing preferred translocation partner in lipoma
chr6_-_134495944	2.268		SGK1	serum/glucocorticoid regulated kinase 1
chr20_+_19867075	2.220	NM_001242581	RIN2	Ras and Rab interactor 2
chr1_-_94702916	2.210		ARHGAP29	Rho GTPase activating protein 29
chr1_-_153518265	2.176	NM_002961 NM_019554	S100A4	S100 calcium binding protein A4
chr8_-_18541441	2.153		PSD3	pleckstrin and Sec7 domain containing 3
chr1_-_94703252	2.054	NM_004815	ARHGAP29	Rho GTPase activating protein 29
chr3_-_123411185	2.028		MYLK	myosin light chain kinase
chr3_+_159557649	2.022	NM_001197109	SCHIP1	schwannomin interacting protein 1
chr13_-_38172862	2.003	NM_001135934 NM_001135935 NM_001135936 NM_006475	POSTN	periostin, osteoblast specific factor
chr13_+_111134933	2.000		COL4A2	collagen, type IV, alpha 2
chr1_+_162602308	1.997		DDR2	discoidin domain receptor tyrosine kinase 2
chr1_+_162602198	1.944	NM_001014796 NM_006182	DDR2	discoidin domain receptor tyrosine kinase 2
chr2_-_56151273	1.875	NM_001039348 NM_001039349	EFEMP1	EGF containing fibulin-like extracellular matrix protein 1
chr9_+_75766777	1.827	NM_000700	ANXA1	annexin A1
chr7_+_93551015	1.811	NM_004126	GNG11	guanine nucleotide binding protein (G protein), gamma 11
chr11_-_104839263	1.774	NM_001225	CASP4	caspase 4, apoptosis-related cysteine peptidase
chr6_-_134496006	1.772	NM_005627	SGK1	serum/glucocorticoid regulated kinase 1
chr1_+_171154387	1.761	NM_001460	FMO2	flavin containing monooxygenase 2 (non-functional)
chr9_-_35689902	1.746	NM_003289 NM_213674	TPM2	tropomyosin 2 (beta)
chrX_+_135251454	1.735	NM_001159704	FHL1	four and a half LIM domains 1
chr9_+_706744	1.692	NM_153186	KANK1	KN motif and ankyrin repeat domains 1
chr6_+_116692098	1.656	NM_013352	DSE	dermatan sulfate epimerase
chr2_-_190044330	1.646	NM_000393	COL5A2	collagen, type V, alpha 2
chr18_+_66465316	1.643	NM_024781	CCDC102B	coiled-coil domain containing 102B
chr4_-_114900802	1.637	NM_024590	ARSJ	arylsulfatase family, member J
chr9_-_35689799	1.634		TPM2	tropomyosin 2 (beta)
chrX_+_135229536	1.629	NM_001159702 NM_001159703 NM_001449	FHL1	four and a half LIM domains 1
chr7_+_23286384	1.620		GPNMB	glycoprotein (transmembrane) nmb
chr3_+_157154579	1.567	NM_002852	PTX3	pentraxin 3, long
chr7_+_94024201	1.523		COL1A2	collagen, type I, alpha 2
chr10_-_126716452	1.493	NM_022802	CTBP2	C-terminal binding protein 2
chr19_+_41725098	1.490	NM_001699 NM_021913	AXL	AXL receptor tyrosine kinase
chr4_+_41258941	1.458		UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr13_-_52980628	1.455	NM_018676 NM_199263	THSD1	thrombospondin, type I, domain containing 1
chr19_-_43709692	1.449	NM_002780 NM_213633	PSG4	pregnancy specific beta-1-glycoprotein 4
chr4_+_41258909	1.447		UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr7_+_23286390	1.434		GPNMB	glycoprotein (transmembrane) nmb
chr15_+_32933869	1.419	NM_001144757 NM_003020	SCG5	secretogranin V (7B2 protein)
chr16_-_65155984	1.417		CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)
chr22_+_33196801	1.404	NM_000362	TIMP3	TIMP metallopeptidase inhibitor 3
chr4_+_41258895	1.403	NM_004181	UCHL1	ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr7_+_23286386	1.382		GPNMB	glycoprotein (transmembrane) nmb
chr2_-_216241321	1.364		FN1	fibronectin 1
chr3_-_149095413	1.363		TM4SF1	transmembrane 4 L six family member 1
chr16_-_65155965	1.349		CDH11	cadherin 11, type 2, OB-cadherin (osteoblast)
chr8_-_49833823	1.346	NM_003068	SNAI2	snail homolog 2 (Drosophila)
chr6_-_112575880	1.328		LAMA4	laminin, alpha 4
chr6_-_112575766	1.319	NM_001105206 NM_001105207 NM_001105208 NM_001105209 NM_002290	LAMA4	laminin, alpha 4
chr5_+_140739589	1.317	NM_018923 NM_032096	PCDHGB2	protocadherin gamma subfamily B, 2
chr3_-_149095517	1.294	NM_014220	TM4SF1	transmembrane 4 L six family member 1
chrX_-_114252132	1.269	NM_000640	IL13RA2	interleukin 13 receptor, alpha 2
chr16_+_29831714	1.266	NM_005115 NM_017458	MVP	major vault protein
chr1_-_153538305	1.259	NM_005978	S100A2	S100 calcium binding protein A2
chr11_-_12030622	1.246	NM_015881	DKK3	dickkopf 3 homolog (Xenopus laevis)
chr1_-_209825797	1.240	NM_000228	LAMB3	laminin, beta 3
chr7_+_100199881	1.227	NM_002593	PCOLCE	procollagen C-endopeptidase enhancer
chr8_+_70405080	1.220		SULF1	sulfatase 1
chr12_-_50616425	1.210	NM_001113547	LIMA1	LIM domain and actin binding 1
chr3_-_149095458	1.208		TM4SF1	transmembrane 4 L six family member 1
chr1_-_32169619	1.202	NM_001856	COL16A1	collagen, type XVI, alpha 1
chr11_+_114167197	1.200		NNMT	nicotinamide N-methyltransferase
chr12_-_52886971	1.176	NM_005554	KRT6A	keratin 6A
chr3_-_149095333	1.173		TM4SF1	transmembrane 4 L six family member 1
chr9_-_129884998	1.169	NM_012098	ANGPTL2	angiopoietin-like 2
chr9_-_88715024	1.167	NM_177937	GOLM1	golgi membrane protein 1
chr18_+_29027731	1.166	NM_001944	DSG3	desmoglein 3
chr3_+_45067750	1.160	NM_003278	CLEC3B	C-type lectin domain family 3, member B
chr3_-_18480203	1.147	NM_001131010	SATB1	SATB homeobox 1
chr3_+_69134057	1.145	NM_006407	ARL6IP5	ADP-ribosylation-like factor 6 interacting protein 5
chr7_-_137028275	1.144		PTN	pleiotrophin
chr12_-_50677238	1.140	NM_001113546 NM_016357	LIMA1	LIM domain and actin binding 1
chr2_+_36583369	1.131	NM_016441	CRIM1	cysteine rich transmembrane BMP regulator 1 (chordin-like)
chr12_-_52867521	1.129	NM_173086	KRT6C	keratin 6C
chr14_-_61748510	1.127	NM_001017970	TMEM30B	transmembrane protein 30B
chr21_-_28339405	1.126	NM_007038	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr9_+_75766794	1.117		ANXA1	annexin A1
chr11_-_12030539	1.111		DKK3	dickkopf 3 homolog (Xenopus laevis)
chr17_-_15164043	1.108	NM_153322	PMP22	peripheral myelin protein 22
chr1_+_203595929	1.107		ATP2B4	ATPase, Ca++ transporting, plasma membrane 4
chr1_-_32169555	1.087		COL16A1	collagen, type XVI, alpha 1
chr2_+_192109879	1.082	NM_001130158 NM_012223 NM_001161819	MYO1B	myosin IB
chr6_-_112575708	1.082		LAMA4	laminin, alpha 4
chr7_-_41742666	1.073	NM_002192	INHBA	inhibin, beta A
chr13_+_102104941	1.065	NM_004791	ITGBL1	integrin, beta-like 1 (with EGF-like repeat domains)
chr4_+_47487230	1.064	NM_020453	ATP10D	ATPase, class V, type 10D
chr22_+_38071612	1.061	NM_002305	LGALS1	lectin, galactoside-binding, soluble, 1
chr18_+_61420276	1.055	NM_001040147	SERPINB7	serpin peptidase inhibitor, clade B (ovalbumin), member 7
chr16_+_82660390	1.053	NM_001220488 NM_001220489 NM_001220490 NM_001220491 NM_001220492 NM_001257	CDH13	cadherin 13, H-cadherin (heart)
chr11_-_12030128	1.046	NM_001018057	DKK3	dickkopf 3 homolog (Xenopus laevis)
chr6_-_2840683	1.039		SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr12_-_91505215	1.038		LUM	lumican
chr11_+_101983170	1.035	NM_001195045	YAP1	Yes-associated protein 1
chr5_-_146833150	1.033	NM_001387	DPYSL3	dihydropyrimidinase-like 3
chr7_+_23286277	1.030	NM_001005340 NM_002510	GPNMB	glycoprotein (transmembrane) nmb
chr7_-_137028433	1.012		PTN	pleiotrophin
chr18_-_21852189	1.010	NM_018030	OSBPL1A	oxysterol binding protein-like 1A
chr1_+_78470593	1.009	NM_007034	DNAJB4	DnaJ (Hsp40) homolog, subfamily B, member 4
chr5_-_150537335	1.007	NM_001155	ANXA6	annexin A6
chr4_-_100242487	1.007	NM_000668	ADH1A ADH1B	alcohol dehydrogenase 1A (class I), alpha polypeptide alcohol dehydrogenase 1B (class I), beta polypeptide
chr1_-_153599969	1.001	NM_001024211	S100A13	S100 calcium binding protein A13
chr21_+_37442221	0.999	NM_001757	CBR1	carbonyl reductase 1
chr5_+_140729723	0.997	NM_018922 NM_032095	PCDHGB1	protocadherin gamma subfamily B, 1
chr5_+_76011780	0.988	NM_001992	F2R	coagulation factor II (thrombin) receptor
chr22_+_31478845	0.986	NM_001207017	SMTN	smoothelin
chr18_-_53068755	0.985		TCF4	transcription factor 4
chr5_+_140868721	0.982	NM_018929 NM_032407	PCDHGC5	protocadherin gamma subfamily C, 5
chr20_-_14318200	0.981	NM_013281 NM_198391	FLRT3	fibronectin leucine rich transmembrane protein 3
chr12_-_52967608	0.969	NM_175053	KRT74	keratin 74
chr5_+_34684611	0.966	NM_001145521 NM_001145525	RAI14	retinoic acid induced 14
chr8_-_95274520	0.963		GEM	GTP binding protein overexpressed in skeletal muscle
chr19_+_38755422	0.953		SPINT2	serine peptidase inhibitor, Kunitz type, 2
chr8_+_17433941	0.951	NM_006207	PDGFRL	platelet-derived growth factor receptor-like
chr8_-_18871163	0.949	NM_015310	PSD3	pleckstrin and Sec7 domain containing 3
chr9_-_13279562	0.949		MPDZ	multiple PDZ domain protein
chr11_+_131240370	0.936	NM_001048209	NTM	neurotrimin
chr14_+_94577078	0.927	NM_001130080 NM_005532	IFI27	interferon, alpha-inducible protein 27
chr5_+_140734767	0.927	NM_018917 NM_032053	PCDHGA4	protocadherin gamma subfamily A, 4
chr3_+_187930720	0.926	NM_005578	LPP	LIM domain containing preferred translocation partner in lipoma
chr7_-_76829109	0.925	NM_006682	FGL2	fibrinogen-like 2
chr12_-_91505541	0.921	NM_002345	LUM	lumican
chr8_-_95274540	0.917	NM_005261 NM_181702	GEM	GTP binding protein overexpressed in skeletal muscle
chrX_-_13835012	0.911		GPM6B	glycoprotein M6B
chrX_-_13835187	0.911		GPM6B	glycoprotein M6B
chr10_+_124151818	0.907	NM_021622	PLEKHA1	pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 1
chr5_+_140810181	0.901		PCDHGA12	protocadherin gamma subfamily A, 12
chr11_+_123986103	0.900	NM_001130142 NM_014622 NM_198315	VWA5A	von Willebrand factor A domain containing 5A
chr7_+_18535817	0.899	NM_058176 NM_178425	HDAC9	histone deacetylase 9
chr12_+_119616594	0.891	NM_014365	HSPB8	heat shock 22kDa protein 8
chr7_+_23286420	0.890		GPNMB	glycoprotein (transmembrane) nmb
chr2_-_55237255	0.889	NM_007008	RTN4	reticulon 4
chr11_-_8892909	0.889		ST5	suppression of tumorigenicity 5
chr1_+_46640748	0.887	NM_005727	TSPAN1	tetraspanin 1
chr5_-_172755418	0.881		STC2	stanniocalcin 2
chr22_-_37164073	0.880	NM_001177702	IFT27	intraflagellar transport 27 homolog (Chlamydomonas)
chr17_+_32582295	0.877	NM_002982	CCL2	chemokine (C-C motif) ligand 2
chr8_+_70405027	0.876	NM_001128205 NM_001128206	SULF1	sulfatase 1
chrX_+_102632108	0.872	NM_014380	NGFRAP1	nerve growth factor receptor (TNFRSF16) associated protein 1
chr16_+_1584161	0.870	NM_024600	TMEM204	transmembrane protein 204
chr7_+_18535351	0.870	NM_001204145 NM_001204146 NM_014707 NM_178423	HDAC9	histone deacetylase 9
chr5_+_140810126	0.866	NM_003735 NM_032094	PCDHGA12	protocadherin gamma subfamily A, 12
chr12_+_12764844	0.858		CREBL2	cAMP responsive element binding protein-like 2
chr3_+_158787040	0.856	NM_001197113 NM_001197114 NM_001042705 NM_001042706 NM_001197100	IQCJ-SCHIP1 IQCJ	IQCJ-SCHIP1 readthrough IQ motif containing J
chr2_-_231989755	0.854	NM_000867	HTR2B	5-hydroxytryptamine (serotonin) receptor 2B
chr1_-_226926875	0.852	NM_002221	ITPKB	inositol-trisphosphate 3-kinase B
chr1_+_164818083	0.851		PBX1	pre-B-cell leukemia homeobox 1
chr18_-_500583	0.843	NM_130386	COLEC12	collectin sub-family member 12
chr16_+_82660573	0.839		CDH13	cadherin 13, H-cadherin (heart)
chr1_+_163038934	0.837	NM_001113381	RGS4	regulator of G-protein signaling 4
chr7_-_137028370	0.833		PTN	pleiotrophin
chr5_+_96211643	0.831	NM_001130140 NM_022350	ERAP2	endoplasmic reticulum aminopeptidase 2
chr14_+_62164339	0.830	NM_001243084	HIF1A	hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
chrX_-_13835313	0.830	NM_001001995 NM_001001996 NM_005278	GPM6B	glycoprotein M6B
chr5_+_140749830	0.828	NM_018924 NM_032097	PCDHGB3	protocadherin gamma subfamily B, 3
chr2_+_113885137	0.823	NM_173842	IL1RN	interleukin 1 receptor antagonist
chr5_+_140797243	0.819	NM_018927	PCDHGB7	protocadherin gamma subfamily B, 7
chr1_-_57045235	0.814	NM_003713	PPAP2B	phosphatidic acid phosphatase type 2B
chr9_+_112542496	0.807	NM_053016 NM_007203 NM_147150	PALM2 PALM2-AKAP2	paralemmin 2 PALM2-AKAP2 readthrough
chr5_+_140753480	0.807	NM_018919 NM_032086	PCDHGA6	protocadherin gamma subfamily A, 6
chr5_-_111093792	0.803	NM_001142477 NM_001142476	C5orf13	chromosome 5 open reading frame 13
chr12_+_49212253	0.791	NM_000725 NM_001206915	CACNB3	calcium channel, voltage-dependent, beta 3 subunit
chrX_-_38079980	0.789	NM_001170750 NM_001170751 NM_001170752 NM_006307	SRPX	sushi-repeat containing protein, X-linked
chr9_-_95298251	0.773	NM_001197295 NM_001197296 NM_001393	ECM2	extracellular matrix protein 2, female organ and adipocyte specific
chr12_-_15038724	0.763	NM_000900 NM_001190839	MGP	matrix Gla protein
chr14_-_53417272	0.761		FERMT2	fermitin family member 2
chr13_-_45150391	0.759		TSC22D1	TSC22 domain family, member 1
chr1_+_101185195	0.759	NM_001078 NM_001199834 NM_080682	VCAM1	vascular cell adhesion molecule 1
chr14_-_69354900	0.758		ACTN1	actinin, alpha 1
chr21_+_39628663	0.751	NM_002243	KCNJ15	potassium inwardly-rectifying channel, subfamily J, member 15

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
3.89	6.37e-04	GO:0007155	cell adhesion
3.89	6.37e-04	GO:0022610	biological adhesion
3.67	6.86e-04	GO:0009888	tissue development
11.08	1.51e-03	GO:0030198	extracellular matrix organization
25.92	7.32e-03	GO:0018149	peptide cross-linking
1.91	1.18e-02	GO:0007275	multicellular organismal development
22.68	1.28e-02	GO:0030199	collagen fibril organization
2.02	1.31e-02	GO:0048731	system development
1.93	1.75e-02	GO:0048856	anatomical structure development
1.83	1.78e-02	GO:0032502	developmental process
7.22	2.52e-02	GO:0043062	extracellular structure organization

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
3.44	5.06e-10	GO:0005576	extracellular region
8.89	2.23e-09	GO:0005578	proteinaceous extracellular matrix
4.40	2.45e-09	GO:0044421	extracellular region part
7.82	3.80e-09	GO:0031012	extracellular matrix
32.98	7.09e-09	GO:0005581	collagen
15.28	1.15e-08	GO:0044420	extracellular matrix part
3.90	2.57e-05	GO:0005615	extracellular space
49.47	8.32e-05	GO:0005583	fibrillar collagen
45.34	3.01e-03	GO:0030934	anchoring collagen
90.68	1.54e-02	GO:0005589	collagen type VI

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
14.01	7.60e-05	GO:0005201	extracellular matrix structural constituent
4.04	4.59e-04	GO:0005198	structural molecule activity
8.51	5.33e-04	GO:0005539	glycosaminoglycan binding
19.44	6.47e-04	GO:0005518	collagen binding
9.73	9.08e-04	GO:0008201	heparin binding
7.89	9.33e-04	GO:0001871	pattern binding
7.89	9.33e-04	GO:0030247	polysaccharide binding
4.51	8.84e-03	GO:0030246	carbohydrate binding
6.67	1.05e-02	GO:0061134	peptidase regulator activity
90.68	1.98e-02	GO:0004024	alcohol dehydrogenase activity, zinc-dependent
4.91	2.74e-02	GO:0004857	enzyme inhibitor activity