Motif ID: PAX2.p2

Z-value: 0.911


Transcription factors associated with PAX2.p2:

Gene SymbolEntrez IDGene Name
PAX2 5076 paired box 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PAX2chr10_+_1025053370.371.5e-01Click!


Activity profile for motif PAX2.p2.

activity profile for motif PAX2.p2


Sorted Z-values histogram for motif PAX2.p2

Sorted Z-values for motif PAX2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PAX2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_127413739 1.280 GYPC
glycophorin C (Gerbich blood group)
chr16_+_23847359 1.057 PRKCB
protein kinase C, beta
chr2_+_127413678 0.905 NM_002101
NM_016815
GYPC

glycophorin C (Gerbich blood group)

chr6_-_90121966 0.821 NM_021244
RRAGD
Ras-related GTP binding D
chr2_-_197036262 0.674 STK17B
serine/threonine kinase 17b
chr2_-_197036301 0.604 NM_004226
STK17B
serine/threonine kinase 17b
chr16_+_23847321 0.562 PRKCB
protein kinase C, beta
chr14_-_106208537 0.559


chr6_-_90121911 0.541 RRAGD
Ras-related GTP binding D
chr18_+_9136742 0.529 NM_001083625
NM_015208
ANKRD12

ankyrin repeat domain 12

chr2_+_74781846 0.517 DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr22_+_22723972 0.508


chr3_-_98241357 0.506 CLDND1
claudin domain containing 1
chr12_-_91572328 0.497 NM_133504
NM_133505
NM_133506
NM_133507
DCN



decorin



chr10_+_11060105 0.495 CELF2
CUGBP, Elav-like family member 2
chr15_+_43809805 0.481 NM_002373
MAP1A
microtubule-associated protein 1A
chr1_+_77747602 0.469 NM_174858
AK5
adenylate kinase 5
chr5_-_81046858 0.469 SSBP2
single-stranded DNA binding protein 2
chr8_-_95274540 0.464 NM_005261
NM_181702
GEM

GTP binding protein overexpressed in skeletal muscle

chr1_+_174843523 0.452 NM_001243763
RABGAP1L
RAB GTPase activating protein 1-like
chr15_-_66084438 0.451 DENND4A
DENN/MADD domain containing 4A
chr17_-_48262900 0.448 COL1A1
collagen, type I, alpha 1
chr10_+_11060069 0.441 CELF2
CUGBP, Elav-like family member 2
chr15_-_66084544 0.440 NM_001144823
NM_005848
DENND4A

DENN/MADD domain containing 4A

chr19_-_45681454 0.432 NM_024108
TRAPPC6A
trafficking protein particle complex 6A
chr1_-_212873306 0.432 NM_018664
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr1_-_27961623 0.431 NM_005248
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr2_+_74781511 0.426 NM_001381
DOK1
docking protein 1, 62kDa (downstream of tyrosine kinase 1)
chr6_-_109703661 0.419 CD164
CD164 molecule, sialomucin
chr11_+_7618416 0.414 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr10_+_69644341 0.397 NM_012238
SIRT1
sirtuin 1
chr17_-_42201009 0.389 NM_001015053
NM_005474
HDAC5

histone deacetylase 5

chr5_-_133706717 0.386 CDKL3
cyclin-dependent kinase-like 3
chr8_-_95274520 0.386 GEM
GTP binding protein overexpressed in skeletal muscle
chr3_+_133118789 0.386 NM_003571
BFSP2
beaded filament structural protein 2, phakinin
chrX_+_128913897 0.374 SASH3
SAM and SH3 domain containing 3
chr12_+_56109851 0.369 BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr17_-_26903854 0.368 ALDOC
aldolase C, fructose-bisphosphate
chr6_-_32920812 0.368 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr12_+_56109817 0.366 NM_001487
BLOC1S1
biogenesis of lysosomal organelles complex-1, subunit 1
chr17_-_26903926 0.364 NM_005165
ALDOC
aldolase C, fructose-bisphosphate
chr12_-_91573264 0.363 NM_133503
DCN
decorin
chrX_+_128913881 0.362 NM_018990
SASH3
SAM and SH3 domain containing 3
chr6_-_109703703 0.359 NM_001142401
NM_001142402
NM_001142403
NM_001142404
NM_006016
CD164




CD164 molecule, sialomucin




chr5_-_150537335 0.355 NM_001155
ANXA6
annexin A6
chr12_+_56109832 0.352 BLOC1S1-RDH5
BLOC1S1
BLOC1S1-RDH5 readthrough
biogenesis of lysosomal organelles complex-1, subunit 1
chr2_-_64881040 0.352 NM_014755
SERTAD2
SERTA domain containing 2
chr1_-_51425464 0.349 FAF1
Fas (TNFRSF6) associated factor 1
chr10_-_98031154 0.348 NM_001114094
NM_013314
BLNK

B-cell linker

chr8_-_71581419 0.346 NM_016027
LACTB2
lactamase, beta 2
chr19_+_50922194 0.339 NM_001243998
NM_001243999
NM_001244000
NM_003121
SPIB



Spi-B transcription factor (Spi-1/PU.1 related)



chr17_-_42200957 0.335 HDAC5
histone deacetylase 5
chr10_-_64576123 0.334 NM_000399
NM_001136177
NM_001136179
EGR2


early growth response 2


chr6_-_90121656 0.332 RRAGD
Ras-related GTP binding D
chr11_+_65479685 0.327 KAT5
K(lysine) acetyltransferase 5
chr6_+_127587984 0.326 RNF146
ring finger protein 146
chr19_+_1067293 0.325 HMHA1
histocompatibility (minor) HA-1
chr5_-_150537306 0.324 ANXA6
annexin A6
chr2_+_46926049 0.322 NM_014011
SOCS5
suppressor of cytokine signaling 5
chr8_+_98656428 0.321 MTDH
metadherin
chr6_+_14117857 0.319 NM_001040280
NM_004233
CD83

CD83 molecule

chr1_-_212873104 0.316 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr1_-_32801606 0.314 NM_023009
MARCKSL1
MARCKS-like 1
chr11_+_7535213 0.313 PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr10_-_64576074 0.307 EGR2
early growth response 2
chr7_+_98246595 0.307 NM_002523
NPTX2
neuronal pentraxin II
chr6_-_109703617 0.306 CD164
CD164 molecule, sialomucin
chr19_+_1067114 0.304 NM_012292
HMHA1
histocompatibility (minor) HA-1
chr19_+_1067536 0.301 HMHA1
histocompatibility (minor) HA-1
chr12_-_7245048 0.298 C1R
complement component 1, r subcomponent
chr5_-_150537261 0.297 ANXA6
annexin A6
chr14_-_91884138 0.295 CCDC88C
coiled-coil domain containing 88C
chr1_+_246887591 0.290 SCCPDH
saccharopine dehydrogenase (putative)
chr3_-_98241683 0.286 CLDND1
claudin domain containing 1
chr19_+_16435734 0.286 KLF2
Kruppel-like factor 2 (lung)
chr5_+_118604417 0.284 NM_001077654
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr12_-_7245006 0.284 NM_001733
C1R
complement component 1, r subcomponent
chr14_+_24584009 0.283 DCAF11
DDB1 and CUL4 associated factor 11
chr1_-_212873197 0.283 BATF3
basic leucine zipper transcription factor, ATF-like 3
chr10_+_76586299 0.282 NM_012330
KAT6B
K(lysine) acetyltransferase 6B
chr2_-_60780404 0.280 NM_018014
NM_022893
NM_138559
BCL11A


B-cell CLL/lymphoma 11A (zinc finger protein)


chrX_-_15873094 0.276 NM_003916
AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr8_+_98656494 0.276 MTDH
metadherin
chr12_-_110434057 0.271 GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
chr11_-_116968986 0.270 NM_025164
SIK3
SIK family kinase 3
chr3_+_113465901 0.269 ATP6V1A
ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A
chr5_-_81046943 0.268 NM_012446
SSBP2
single-stranded DNA binding protein 2
chr2_-_211179765 0.267 NM_079420
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr21_-_43816123 0.266 NM_024022
NM_032405
TMPRSS3

transmembrane protease, serine 3

chr5_+_118604504 0.265 TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr21_-_28339405 0.265 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr6_+_127587826 0.264 NM_001242851
NM_001242844
NM_001242849
NM_001242852
NM_001242845
NM_001242846
NM_001242850
NM_030963
RNF146







ring finger protein 146







chr1_-_202896315 0.264 KLHL12
kelch-like 12 (Drosophila)
chr16_+_23847271 0.263 NM_002738
NM_212535
PRKCB

protein kinase C, beta

chr1_+_181002560 0.262 NM_001194999
NM_001195000
NM_001195035
NM_001531
MR1



major histocompatibility complex, class I-related



chr12_-_63328857 0.261 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr6_+_138188352 0.261 NM_006290
TNFAIP3
tumor necrosis factor, alpha-induced protein 3
chr14_+_24584321 0.261 DCAF11
DDB1 and CUL4 associated factor 11
chr14_-_64970319 0.260 NM_006977
ZBTB25
zinc finger and BTB domain containing 25
chr5_+_110074708 0.259 SLC25A46
solute carrier family 25, member 46
chrX_+_30671456 0.257 NM_000167
NM_001128127
NM_001205019
NM_203391
GK



glycerol kinase



chr3_+_158519888 0.253 MFSD1
major facilitator superfamily domain containing 1
chr7_-_87505640 0.252 SLC25A40
solute carrier family 25, member 40
chr1_+_6052357 0.251 NM_001199861
KCNAB2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr3_-_8811263 0.251 NM_000916
OXTR
oxytocin receptor
chr8_+_86089618 0.249 NM_001083588
NM_001951
E2F5

E2F transcription factor 5, p130-binding

chrX_-_106960028 0.248 TSC22D3
TSC22 domain family, member 3
chr6_-_144329342 0.248 NM_001080952
NM_001080953
NM_001080954
NM_001080956
NM_002656
NM_006718
PLAGL1





HYMAI
pleiomorphic adenoma gene-like 1





hydatidiform mole associated and imprinted (non-protein coding)
chr12_-_63328663 0.246 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr12_-_53601051 0.245 ITGB7
integrin, beta 7
chr5_+_110074740 0.244 NM_138773
SLC25A46
solute carrier family 25, member 46
chr11_-_108093328 0.243 NM_002519
NPAT
nuclear protein, ataxia-telangiectasia locus
chr19_-_36236291 0.243 NM_001040425
NM_144987
U2AF1L4

U2 small nuclear RNA auxiliary factor 1-like 4

chr12_-_109027654 0.242 NM_003006
SELPLG
selectin P ligand
chr7_-_97501680 0.242 ASNS
asparagine synthetase (glutamine-hydrolyzing)
chr2_+_30454396 0.242 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr3_-_195808997 0.241 NM_001128148
TFRC
transferrin receptor (p90, CD71)
chr1_-_11866079 0.237 NM_005957
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr19_-_41256371 0.236 C19orf54
chromosome 19 open reading frame 54
chr1_+_161284165 0.235 NM_001035511
NM_001035512
NM_001035513
NM_003001
SDHC



succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa



chr6_-_49604524 0.235 NM_000324
RHAG
Rh-associated glycoprotein
chr17_-_40540576 0.235 STAT3
signal transducer and activator of transcription 3 (acute-phase response factor)
chr4_+_113739203 0.234 NM_001127493
ANK2
ankyrin 2, neuronal
chr1_-_202896368 0.234 NM_021633
KLHL12
kelch-like 12 (Drosophila)
chr2_-_240964717 0.233 NDUFA10
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa
chr20_+_44519965 0.232 CTSA
cathepsin A
chr12_+_81110689 0.231 NM_005593
MYF5
myogenic factor 5
chr10_-_93392857 0.231 NM_005398
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr10_+_104155431 0.230 NM_002502
NFKB2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
chr2_+_231729638 0.230 ITM2C
integral membrane protein 2C
chr6_-_46293404 0.229 RCAN2
regulator of calcineurin 2
chr1_+_51435641 0.228 NM_078626
CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr19_-_11308184 0.227 NM_001136191
KANK2
KN motif and ankyrin repeat domains 2
chr6_+_30524485 0.226 NM_001077497
NM_025263
PRR3

proline rich 3

chr17_-_29641068 0.225 EVI2B
ecotropic viral integration site 2B
chrX_-_15872938 0.224 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr6_-_53213699 0.224 ELOVL5
ELOVL fatty acid elongase 5
chr11_+_65479472 0.224 NM_001206833
NM_006388
NM_182709
NM_182710
KAT5



K(lysine) acetyltransferase 5



chrX_-_15872882 0.224 AP1S2
adaptor-related protein complex 1, sigma 2 subunit
chr3_-_195808958 0.224 NM_003234
TFRC
transferrin receptor (p90, CD71)
chr14_+_24583979 0.223 NM_025230
DCAF11
DDB1 and CUL4 associated factor 11
chr5_+_133451297 0.222 NM_001134851
NM_201632
NM_201634
NM_213648
TCF7



transcription factor 7 (T-cell specific, HMG-box)



chr1_-_111743297 0.220 DENND2D
DENN/MADD domain containing 2D
chr17_-_29641094 0.220 NM_006495
EVI2B
ecotropic viral integration site 2B
chr15_+_33010174 0.220 NM_001191322
NM_001191323
NM_013372
GREM1


gremlin 1


chr8_+_97506478 0.220 SDC2
syndecan 2
chr6_+_14118002 0.218 CD83
CD83 molecule
chr1_-_51425918 0.218 NM_007051
FAF1
Fas (TNFRSF6) associated factor 1
chr10_+_69644708 0.218 SIRT1
sirtuin 1
chr1_+_33283042 0.216 NM_001017406
NM_022753
S100PBP

S100P binding protein

chr12_+_72148653 0.215 NM_014999
RAB21
RAB21, member RAS oncogene family
chr6_-_109703603 0.214 CD164
CD164 molecule, sialomucin
chr18_+_21083439 0.214 NM_013326
C18orf8
chromosome 18 open reading frame 8
chr1_-_154531083 0.214 NM_017582
UBE2Q1
ubiquitin-conjugating enzyme E2Q family member 1
chr6_+_32821924 0.213 NM_002800
PSMB9
proteasome (prosome, macropain) subunit, beta type, 9 (large multifunctional peptidase 2)
chr10_+_88428167 0.212 NM_001171610
LDB3
LIM domain binding 3
chr15_-_80263460 0.211 NM_001114735
NM_004049
BCL2A1

BCL2-related protein A1

chr1_+_33116748 0.210 NM_001135255
NM_005610
NM_001135256
RBBP4


retinoblastoma binding protein 4


chr1_+_242011471 0.210 NM_130398
EXO1
exonuclease 1
chr2_+_42396392 0.210 NM_001145076
NM_019063
EML4

echinoderm microtubule associated protein like 4

chr3_-_98241748 0.209 CLDND1
claudin domain containing 1
chr1_-_11865963 0.208 MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr21_-_38639593 0.207 DSCR3
Down syndrome critical region gene 3
chr20_+_44519924 0.206 CTSA
cathepsin A
chr1_-_51425829 0.205 FAF1
Fas (TNFRSF6) associated factor 1
chr1_-_51425740 0.205 FAF1
Fas (TNFRSF6) associated factor 1
chr3_+_139654001 0.204 NM_022131
CLSTN2
calsyntenin 2
chr6_-_33385814 0.204


chr14_+_24583905 0.202 NM_001163484
DCAF11
DDB1 and CUL4 associated factor 11
chr2_+_220042901 0.202 NM_024293
FAM134A
family with sequence similarity 134, member A
chrX_+_106871653 0.202 NM_001204402
NM_002764
PRPS1

phosphoribosyl pyrophosphate synthetase 1

chr14_+_55738102 0.202 FBXO34
F-box protein 34
chr16_-_23521755 0.201 GGA2
golgi-associated, gamma adaptin ear containing, ARF binding protein 2
chr3_-_182880463 0.201 NM_014398
LAMP3
lysosomal-associated membrane protein 3
chr12_+_7023490 0.200 NM_001975
ENO2
enolase 2 (gamma, neuronal)
chr10_-_93392744 0.200 PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr7_+_150068252 0.200 NM_014374
REPIN1
replication initiator 1
chr12_-_58146025 0.199 CDK4
cyclin-dependent kinase 4
chr1_-_51425795 0.199 FAF1
Fas (TNFRSF6) associated factor 1
chr6_-_109703553 0.199 CD164
CD164 molecule, sialomucin
chr11_+_67776016 0.197 NM_001161473
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chr3_-_195808934 0.197 TFRC
transferrin receptor (p90, CD71)
chr6_-_111804413 0.196 NM_002912
REV3L
REV3-like, catalytic subunit of DNA polymerase zeta (yeast)
chr7_-_140624280 0.196 NM_004333
BRAF
v-raf murine sarcoma viral oncogene homolog B1
chr11_-_66234176 0.195 MRPL11
mitochondrial ribosomal protein L11
chr6_+_160390128 0.194 NM_000876
IGF2R
insulin-like growth factor 2 receptor
chr2_+_75061234 0.193 HK2
hexokinase 2
chr21_+_47545896 0.191 COL6A2
collagen, type VI, alpha 2
chr6_-_43027114 0.191 NM_015950
MRPL2
mitochondrial ribosomal protein L2
chr12_+_51157636 0.191 NM_005171
ATF1
activating transcription factor 1
chr1_+_242011544 0.191 EXO1
exonuclease 1
chr7_+_150065968 0.191 REPIN1
replication initiator 1
chr2_-_172017358 0.191 NM_012290
TLK1
tousled-like kinase 1
chr12_-_109027565 0.191 SELPLG
selectin P ligand
chr5_-_150138081 0.190 NM_001135644
DCTN4
dynactin 4 (p62)
chr20_+_34359904 0.189 NM_016436
PHF20
PHD finger protein 20
chr1_-_31845818 0.189 NM_004102
FABP3
fatty acid binding protein 3, muscle and heart (mammary-derived growth inhibitor)
chr19_-_48018277 0.188 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr19_-_11688508 0.188 NM_001611
ACP5
acid phosphatase 5, tartrate resistant
chr12_-_58146108 0.188 CDK4
cyclin-dependent kinase 4

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.