Motif ID: RBPJ.p2

Z-value: 1.005


Transcription factors associated with RBPJ.p2:

Gene SymbolEntrez IDGene Name
RBPJ 3516 recombination signal binding protein for immunoglobulin kappa J region

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
RBPJchr4_+_26321307-0.126.6e-01Click!


Activity profile for motif RBPJ.p2.

activity profile for motif RBPJ.p2


Sorted Z-values histogram for motif RBPJ.p2

Sorted Z-values for motif RBPJ.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of RBPJ.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_160681552 2.993 NM_001778
CD48
CD48 molecule
chr22_+_22697538 2.055


chr11_-_111250156 1.550 NM_006235
POU2AF1
POU class 2 associating factor 1
chr2_-_160761192 1.521 LY75-CD302
LY75
LY75-CD302 readthrough
lymphocyte antigen 75
chrX_-_70331297 1.501 NM_000206
IL2RG
interleukin 2 receptor, gamma
chr9_-_123676849 1.449 NM_001190947
TRAF1
TNF receptor-associated factor 1
chr9_-_123688352 1.365 TRAF1
TNF receptor-associated factor 1
chr9_-_123689172 1.290 NM_005658
TRAF1
TNF receptor-associated factor 1
chr11_-_111249902 1.275 POU2AF1
POU class 2 associating factor 1
chr1_+_111413820 1.128 NM_001040033
CD53
CD53 molecule
chrX_+_24483343 1.083 NM_001142386
NM_005391
PDK3

pyruvate dehydrogenase kinase, isozyme 3

chr2_-_163174816 0.915 NM_022168
IFIH1
interferon induced with helicase C domain 1
chr2_-_160761266 0.846 NM_001198759
NM_001198760
NM_002349
LY75-CD302

LY75
LY75-CD302 readthrough

lymphocyte antigen 75
chr15_+_91260575 0.818 NM_000057
BLM
Bloom syndrome, RecQ helicase-like
chr8_+_96145968 0.711 PLEKHF2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr11_-_58345593 0.660 NM_001143995
LPXN
leupaxin
chr8_+_96145942 0.659 NM_024613
PLEKHF2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr16_+_23690190 0.654 PLK1
polo-like kinase 1
chr8_+_96146097 0.649 PLEKHF2
pleckstrin homology domain containing, family F (with FYVE domain) member 2
chr12_-_57146081 0.638 NM_000946
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr17_+_7942351 0.628 NM_001039130
NM_001039131
NM_001141
ALOX15B


arachidonate 15-lipoxygenase, type B


chr8_-_81083660 0.627 NM_001025253
NM_005079
TPD52

tumor protein D52

chr14_-_106926393 0.623 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr3_+_193853937 0.611 HES1
hairy and enhancer of split 1, (Drosophila)
chr12_+_7060531 0.606 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr16_+_23690234 0.589 PLK1
polo-like kinase 1
chr12_+_7060538 0.583 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr12_+_7060517 0.581 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr5_-_169724817 0.573 NM_005565
LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr16_+_23690212 0.557 PLK1
polo-like kinase 1
chr16_+_23690191 0.548 NM_005030
PLK1
polo-like kinase 1
chr14_-_23285011 0.546 NM_001126105
SLC7A7
solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr16_+_23690160 0.531 PLK1
polo-like kinase 1
chr12_+_9822205 0.523 NM_001197318
NM_013269
NM_001004419
NM_001197317
NM_001197319
CLEC2D




C-type lectin domain family 2, member D




chr16_+_30194730 0.513 NM_001193333
NM_007074
CORO1A

coronin, actin binding protein, 1A

chr19_-_51504799 0.508 NM_007196
NM_144505
NM_144506
NM_144507
KLK8



kallikrein-related peptidase 8



chr12_+_7060433 0.506 NM_002831
NM_080549
PTPN6

protein tyrosine phosphatase, non-receptor type 6

chr15_-_66084438 0.506 DENND4A
DENN/MADD domain containing 4A
chr6_-_32812189 0.504 PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr12_+_7060543 0.502 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr5_+_112312392 0.495 NM_001242377
NM_152624
DCP2

DCP2 decapping enzyme homolog (S. cerevisiae)

chr19_-_50528683 0.477 NM_001025778
NM_016440
VRK3

vaccinia related kinase 3

chr1_+_212209129 0.469 DTL
denticleless homolog (Drosophila)
chr12_+_7060554 0.467 PTPN6
protein tyrosine phosphatase, non-receptor type 6
chr2_-_158300517 0.466 NM_004288
CYTIP
cytohesin 1 interacting protein
chr5_+_137514753 0.463 KIF20A
kinesin family member 20A
chr17_-_26926044 0.462 NM_006461
SPAG5
sperm associated antigen 5
chr14_-_105261850 0.459 AKT1
v-akt murine thymoma viral oncogene homolog 1
chr15_-_66084544 0.452 NM_001144823
NM_005848
DENND4A

DENN/MADD domain containing 4A

chr19_-_6481765 0.451 NM_024898
DENND1C
DENN/MADD domain containing 1C
chr19_-_50528627 0.437 VRK3
vaccinia related kinase 3
chr4_-_84255999 0.435 HPSE
heparanase
chr16_+_85932766 0.434 NM_002163
IRF8
interferon regulatory factor 8
chr4_-_84256304 0.431 NM_001166498
NM_006665
HPSE

heparanase

chr19_-_2042022 0.430 MKNK2
MAP kinase interacting serine/threonine kinase 2
chrX_+_24073060 0.425 NM_001415
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr1_+_212208918 0.423 NM_016448
DTL
denticleless homolog (Drosophila)
chr22_-_46933066 0.419 NM_014246
CELSR1
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr14_+_97263681 0.418 NM_003384
VRK1
vaccinia related kinase 1
chrX_+_24073071 0.417 EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr1_+_111682881 0.417 CEPT1
choline/ethanolamine phosphotransferase 1
chr12_-_9913415 0.415 NM_001781
CD69
CD69 molecule
chr2_-_175547471 0.414 NM_001077269
WIPF1
WAS/WASL interacting protein family, member 1
chr18_-_47814024 0.413 CXXC1
CXXC finger protein 1
chr16_+_30194925 0.409 CORO1A
coronin, actin binding protein, 1A
chr7_+_47694841 0.405 NM_001123065
C7orf65
chromosome 7 open reading frame 65
chr14_-_106725620 0.402 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr4_-_84256012 0.401 NM_001098540
HPSE
heparanase
chr9_-_130712866 0.400 NM_203305
FAM102A
family with sequence similarity 102, member A
chr22_+_40322609 0.393 GRAP2
GRB2-related adaptor protein 2
chr2_-_192015706 0.390 STAT4
signal transducer and activator of transcription 4
chr1_-_25256767 0.387 NM_004350
RUNX3
runt-related transcription factor 3
chr18_-_47814187 0.387 CXXC1
CXXC finger protein 1
chrX_-_73834460 0.384 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr18_-_47814005 0.383 CXXC1
CXXC finger protein 1
chr9_+_100174369 0.378 TDRD7
tudor domain containing 7
chr17_+_18759611 0.378 NM_001243936
NM_001243942
PRPSAP2

phosphoribosyl pyrophosphate synthetase-associated protein 2

chr10_+_94352809 0.376 NM_004523
KIF11
kinesin family member 11
chr17_-_56160564 0.375


chr14_-_93214873 0.371 NM_001008530
NM_005606
LGMN

legumain

chr5_-_169724734 0.366 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr5_-_169724782 0.363 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr14_-_107013474 0.360 IGHA1
IGHG1
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
chr7_-_99699426 0.357 NM_005916
MCM7
minichromosome maintenance complex component 7
chr20_+_9494995 0.351 NM_001199897
NM_012261
LAMP5

lysosomal-associated membrane protein family, member 5

chr2_-_192015751 0.349 STAT4
signal transducer and activator of transcription 4
chr11_-_87908551 0.349 NM_022337
RAB38
RAB38, member RAS oncogene family
chr2_-_161056762 0.348 ITGB6
integrin, beta 6
chr22_-_37640287 0.340 NM_002872
RAC2
ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
chr5_+_85913762 0.340 NM_001867
COX7C
cytochrome c oxidase subunit VIIc
chr8_+_123794043 0.340 ZHX2
zinc fingers and homeoboxes 2
chr6_-_32805819 0.338 TAP2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr4_-_84255895 0.334 NM_001199830
HPSE
heparanase
chrX_-_19140581 0.333 NM_001079858
NM_001079859
NM_001079860
NM_001184833
NM_001184834
NM_001184835
NM_001184836
NM_001184837
NM_005756
GPR64








G protein-coupled receptor 64








chr17_-_26926015 0.331 SPAG5
sperm associated antigen 5
chr6_-_32811773 0.323 NM_148919
PSMB8
proteasome (prosome, macropain) subunit, beta type, 8 (large multifunctional peptidase 7)
chr10_+_94352873 0.319 KIF11
kinesin family member 11
chr5_-_176836535 0.317 NM_000505
F12
coagulation factor XII (Hageman factor)
chr2_-_192016293 0.316 NM_001243835
STAT4
signal transducer and activator of transcription 4
chr19_+_50180408 0.315 NM_001207042
NM_001536
NM_198318
PRMT1


protein arginine methyltransferase 1


chr19_+_44716683 0.315 NM_182490
ZNF227
zinc finger protein 227
chr19_-_2041862 0.312 MKNK2
MAP kinase interacting serine/threonine kinase 2
chr2_-_192015934 0.312 NM_003151
STAT4
signal transducer and activator of transcription 4
chr2_-_161056573 0.312 NM_000888
ITGB6
integrin, beta 6
chr19_+_52772847 0.310 ZNF766
zinc finger protein 766
chr7_-_99699030 0.310 MCM7
minichromosome maintenance complex component 7
chr12_-_49392909 0.309 NM_015086
DDN
dendrin
chr3_+_121554029 0.305 NM_018456
EAF2
ELL associated factor 2
chr7_-_128045995 0.304 NM_001142573
NM_001142574
NM_001142575
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chr7_-_99698993 0.304 MCM7
minichromosome maintenance complex component 7
chr2_-_192015733 0.302 STAT4
signal transducer and activator of transcription 4
chr14_+_39736529 0.298 CTAGE5
CTAGE family, member 5
chr19_-_50528576 0.296 VRK3
vaccinia related kinase 3
chr1_-_45805606 0.293 NM_001048174
NM_001048172
NM_001048173
NM_001048171
NM_001128425
NM_012222
MUTYH





mutY homolog (E. coli)





chr7_-_75115536 0.291 NM_001099415
POM121C
POM121 membrane glycoprotein C
chr18_+_10526095 0.289 NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr5_-_693413 0.289 NM_007030
TPPP
tubulin polymerization promoting protein
chr5_-_39074478 0.289 RICTOR
RPTOR independent companion of MTOR, complex 2
chr14_-_106994001 0.285 IGHV3-48
IGH@
IGHA1
IGHM
immunoglobulin heavy variable 3-48
immunoglobulin heavy locus
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant mu
chr10_+_70847857 0.283 SRGN
serglycin
chr5_-_149792276 0.283 CD74
CD74 molecule, major histocompatibility complex, class II invariant chain
chr8_+_123793988 0.280 ZHX2
zinc fingers and homeoboxes 2
chr20_+_47895168 0.278 ZNFX1-AS1
ZNFX1 antisense RNA 1 (non-protein coding)
chr5_-_169724614 0.277 LCP2
lymphocyte cytosolic protein 2 (SH2 domain containing leukocyte protein of 76kDa)
chr18_+_10526022 0.276 NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr19_+_52772823 0.274 NM_001010851
ZNF766
zinc finger protein 766
chr13_+_37006408 0.272 NM_001111045
NM_003914
CCNA1

cyclin A1

chr18_-_28622624 0.268 NM_001941
NM_024423
DSC3

desmocollin 3

chr8_+_123793894 0.267 NM_014943
ZHX2
zinc fingers and homeoboxes 2
chr6_+_29691116 0.267 NM_001098478
NM_001098479
NM_018950
HLA-F


major histocompatibility complex, class I, F


chr22_-_39268169 0.266 CBX6
chromobox homolog 6
chr18_+_10525861 0.266 NM_003826
NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr9_-_115095933 0.264 NM_001163788
NM_001163790
NM_001244896
NM_001244897
NM_005156
PTBP3




polypyrimidine tract binding protein 3




chr8_-_124408688 0.263 NM_014109
ATAD2
ATPase family, AAA domain containing 2
chr13_-_74708361 0.261 KLF12
Kruppel-like factor 12
chr7_-_99698916 0.258 MCM7
minichromosome maintenance complex component 7
chr3_-_47823386 0.258 NM_003074
SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr10_+_47746919 0.257 NM_001630
ANXA8L2
ANXA8
annexin A8-like 2
annexin A8
chr1_-_27961623 0.251 NM_005248
FGR
Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr8_+_145149936 0.250 NM_001916
CYC1
cytochrome c-1
chr2_-_37458695 0.247 NM_005760
CEBPZ
CCAAT/enhancer binding protein (C/EBP), zeta
chr10_+_114133775 0.247 ACSL5
acyl-CoA synthetase long-chain family member 5
chr6_+_42531951 0.243 UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr10_+_124913884 0.237 BUB3
budding uninhibited by benzimidazoles 3 homolog (yeast)
chr2_-_170219012 0.235 NM_004525
LRP2
low density lipoprotein receptor-related protein 2
chr8_-_28347733 0.235 NM_172366
FBXO16
ZNF395
F-box protein 16
zinc finger protein 395
chrX_-_31284946 0.233 NM_004015
NM_004016
NM_004017
NM_004018
NM_004019
DMD




dystrophin




chr9_+_100263818 0.233 NM_003275
TMOD1
tropomodulin 1
chr11_-_113746205 0.232 NM_020886
USP28
ubiquitin specific peptidase 28
chr1_+_86889768 0.232 NM_006536
CLCA2
chloride channel accessory 2
chr12_+_25205180 0.232 NM_001204126
NM_001204127
NM_006152
LRMP


lymphoid-restricted membrane protein


chr16_+_68771192 0.232 NM_004360
CDH1
cadherin 1, type 1, E-cadherin (epithelial)
chr21_-_18985104 0.231 BTG3
BTG family, member 3
chr17_+_25958245 0.231 LGALS9
lectin, galactoside-binding, soluble, 9
chr18_+_10526044 0.229 NAPG
N-ethylmaleimide-sensitive factor attachment protein, gamma
chr12_-_26985922 0.226 NM_002223
ITPR2
inositol 1,4,5-trisphosphate receptor, type 2
chr11_+_61129831 0.225 TMEM138
transmembrane protein 138
chrX_-_72434656 0.225 NAP1L2
nucleosome assembly protein 1-like 2
chr3_-_47823343 0.225 SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chrX_+_150884506 0.224 NM_033085
FATE1
fetal and adult testis expressed 1
chr5_+_6633499 0.222 NM_001047
SRD5A1
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
chr1_-_185286460 0.220 NM_006469
IVNS1ABP
influenza virus NS1A binding protein
chr7_-_16844606 0.220 NM_006408
AGR2
anterior gradient 2 homolog (Xenopus laevis)
chr7_-_45151272 0.220 TBRG4
transforming growth factor beta regulator 4
chr15_-_38856830 0.220 NM_001128602
NM_005739
RASGRP1

RAS guanyl releasing protein 1 (calcium and DAG-regulated)

chr17_-_29151724 0.219 NM_015986
CRLF3
cytokine receptor-like factor 3
chrX_-_118726852 0.216 NM_001173488
NKRF
NFKB repressing factor
chr5_-_169816637 0.215 NM_004137
KCNMB1
potassium large conductance calcium-activated channel, subfamily M, beta member 1
chr8_-_22550057 0.214 NM_001199881
EGR3
early growth response 3
chr4_+_39460643 0.212 NM_006859
NM_194451
LIAS

lipoic acid synthetase

chr1_-_35324645 0.211 NM_001164824
C1orf212
chromosome 1 open reading frame 212
chr17_-_29151638 0.210 CRLF3
cytokine receptor-like factor 3
chr12_-_120907411 0.208 SRSF9
serine/arginine-rich splicing factor 9
chr5_+_133861685 0.208 NM_015288
PHF15
PHD finger protein 15
chr11_+_44587140 0.208 NM_001024844
NM_002231
CD82

CD82 molecule

chr7_+_150130741 0.208 LOC285972
uncharacterized LOC285972
chr5_+_6633659 0.207 SRD5A1
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
chr5_+_175815730 0.207 NM_138820
HIGD2A
HIG1 hypoxia inducible domain family, member 2A
chr19_-_42746678 0.206 GSK3A
glycogen synthase kinase 3 alpha
chr2_+_172821874 0.206 HAT1
histone acetyltransferase 1
chr1_-_59042827 0.205 TACSTD2
tumor-associated calcium signal transducer 2
chr1_+_155108276 0.205 NM_001122837
NM_001122839
NM_018845
SLC50A1


solute carrier family 50 (sugar transporter), member 1


chr19_-_19754452 0.205 NM_016573
GMIP
GEM interacting protein
chr3_-_47823337 0.204 SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr2_+_102615456 0.204 NM_173343
IL1R2
interleukin 1 receptor, type II
chr12_-_120907535 0.204 NM_003769
SRSF9
serine/arginine-rich splicing factor 9
chrX_+_123094377 0.203 NM_001042749
STAG2
stromal antigen 2
chr12_+_8276227 0.200 NM_016184
NM_194447
NM_194448
NM_194450
CLEC4A



C-type lectin domain family 4, member A



chr19_-_37019169 0.200 NM_001012756
NM_001166036
NM_001166037
NM_001166038
ZNF260



zinc finger protein 260



chr1_+_955468 0.200 NM_198576
AGRN
agrin
chr14_-_96180402 0.199 NM_001098725
NM_021966
TCL1A

T-cell leukemia/lymphoma 1A

chr21_+_42797977 0.199 NM_002462
NM_001178046
MX1

myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)

chrX_-_100662788 0.199 GLA
galactosidase, alpha
chr14_-_106691698 0.198


chr5_+_85913755 0.198 COX7C
cytochrome c oxidase subunit VIIc
chr6_-_53409897 0.198 NM_001197115
NM_001498
GCLC

glutamate-cysteine ligase, catalytic subunit

chr17_+_26698986 0.198 NM_015077
SARM1
sterile alpha and TIR motif containing 1
chr5_+_68788387 0.198 NM_001205254
OCLN
occludin
chr9_-_95896498 0.197 NM_004148
NINJ1
ninjurin 1
chr19_+_5681139 0.195 HSD11B1L
hydroxysteroid (11-beta) dehydrogenase 1-like

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.