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Motif ID: TBP.p2

Z-value: 3.338

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr16_+_56685810	10.655	NM_005947	MT1B	metallothionein 1B
chr1_-_59042827	10.392		TACSTD2	tumor-associated calcium signal transducer 2
chr16_+_56659584	10.315	NM_175617	MT1E	metallothionein 1E
chr17_-_39780762	10.267	NM_000422	KRT17	keratin 17
chr16_+_56659679	10.133		MT1E	metallothionein 1E
chr4_+_75310852	10.017	NM_001657	AREG	amphiregulin
chr1_+_153003677	9.673	NM_003125	SPRR1B	small proline-rich protein 1B
chr12_-_52886971	9.636	NM_005554	KRT6A	keratin 6A
chr2_-_151344145	9.570	NM_005168	RND3	Rho family GTPase 3
chr12_-_52867521	9.326	NM_173086	KRT6C	keratin 6C
chr2_-_216300770	8.922	NM_002026 NM_054034 NM_212474 NM_212476 NM_212478 NM_212482	FN1	fibronectin 1
chr21_-_28217692	8.371	NM_006988	ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr12_-_53012332	8.301	NM_175068	KRT73	keratin 73
chr11_-_2950593	8.136	NM_003311	PHLDA2	pleckstrin homology-like domain, family A, member 2
chr1_-_153363544	7.998	NM_002964	S100A8	S100 calcium binding protein A8
chr7_+_100770378	7.970	NM_000602 NM_001165413	SERPINE1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
chr21_-_28217272	7.918		ADAMTS1	ADAM metallopeptidase with thrombospondin type 1 motif, 1
chr10_+_54074037	7.885	NM_012242	DKK1	dickkopf 1 homolog (Xenopus laevis)
chr16_+_56716378	7.555	NM_005952	MT1X	metallothionein 1X
chr15_-_63674074	7.305	NM_001218 NM_206925	CA12	carbonic anhydrase XII
chr12_-_52845862	7.286	NM_005555	KRT6B	keratin 6B
chr15_-_63673918	6.577		CA12	carbonic anhydrase XII
chr16_+_56672577	6.560	NM_005946	MT1A	metallothionein 1A
chr1_-_95007139	6.338	NM_001178096 NM_001993	F3	coagulation factor III (thromboplastin, tissue factor)
chr8_-_23261626	6.229		LOXL2	lysyl oxidase-like 2
chr1_+_153330329	5.957	NM_002965	S100A9	S100 calcium binding protein A9
chr6_-_169653922	5.568		THBS2	thrombospondin 2
chr8_-_23261591	5.527		LOXL2	lysyl oxidase-like 2
chr12_+_52627007	5.328		KRT7	keratin 7
chr8_-_24814028	5.062	NM_006158	NEFL	neurofilament, light polypeptide
chr12_+_13044352	4.919		GPRC5A	G protein-coupled receptor, family C, group 5, member A
chr16_+_56598960	4.669	NM_032935	MT4	metallothionein 4
chr9_-_117880411	4.620	NM_002160	TNC	tenascin C
chr5_-_57755787	4.590	NM_001252226 NM_006622	PLK2	polo-like kinase 2
chr13_-_45150391	4.432		TSC22D1	TSC22 domain family, member 1
chr6_-_2842069	4.377	NM_030666	SERPINB1	serpin peptidase inhibitor, clade B (ovalbumin), member 1
chr9_+_124048396	4.109		GSN	gelsolin
chr10_+_17271276	4.063		VIM	vimentin
chr1_+_152881022	3.934	NM_005547	IVL	involucrin
chr15_+_39873276	3.789	NM_003246	THBS1	thrombospondin 1
chr14_-_53417808	3.776	NM_001134999 NM_001135000 NM_006832	FERMT2	fermitin family member 2
chr1_-_153518265	3.759	NM_002961 NM_019554	S100A4	S100 calcium binding protein A4
chr8_-_48650703	3.728	NM_005195	CEBPD	CCAAT/enhancer binding protein (C/EBP), delta
chr11_+_18287807	3.707	NM_000331 NM_001178006 NM_199161	SAA1	serum amyloid A1
chr10_+_17271277	3.700		VIM	vimentin
chr16_-_56701904	3.689	NM_005950	MT1G	metallothionein 1G
chr4_+_74735107	3.642	NM_001511	CXCL1	chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha)
chr5_-_16742336	3.583		MYO10	myosin X
chr22_-_36236330	3.516		RBFOX2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr15_+_81071708	3.371	NM_018689	KIAA1199	KIAA1199
chr22_+_31480981	3.360	NM_001207018	SMTN	smoothelin
chr6_-_134498973	3.349	NM_001143677	SGK1	serum/glucocorticoid regulated kinase 1
chr6_-_52860076	3.313	NM_001512	GSTA4	glutathione S-transferase alpha 4
chr17_-_39768939	3.229	NM_005557	KRT16	keratin 16
chr20_-_43977023	3.203	NM_002999	SDC4	syndecan 4
chr1_-_153029987	3.127	NM_005988	SPRR2A	small proline-rich protein 2A
chr1_-_201465700	2.968	NM_001193572	CSRP1	cysteine and glycine-rich protein 1
chr11_-_102651321	2.929	NM_002425	MMP10	matrix metallopeptidase 10 (stromelysin 2)
chr17_-_39675078	2.909	NM_002275	KRT15	keratin 15
chr17_-_39553796	2.868	NM_002277	KRT31	keratin 31
chr8_-_23261632	2.826		LOXL2	lysyl oxidase-like 2
chr1_+_86046434	2.799	NM_001554	CYR61	cysteine-rich, angiogenic inducer, 61
chr3_+_62304667	2.797		C3orf14	chromosome 3 open reading frame 14
chr5_-_42811959	2.778	NM_001085486 NM_001093726 NM_005410	SEPP1	selenoprotein P, plasma, 1
chr7_-_41742666	2.759	NM_002192	INHBA	inhibin, beta A
chr15_-_60690115	2.698	NM_001002857 NM_001002858 NM_001136015 NM_004039	ANXA2	annexin A2
chr12_-_53074172	2.686	NM_006121	KRT1	keratin 1
chr7_-_559479	2.630	NM_002607 NM_033023	PDGFA	platelet-derived growth factor alpha polypeptide
chr7_+_134464161	2.620	NM_004342 NM_033138 NM_033157	CALD1	caldesmon 1
chr9_-_33447527	2.603	NM_004925	AQP3	aquaporin 3 (Gill blood group)
chr14_+_75745480	2.488	NM_005252	FOS	FBJ murine osteosarcoma viral oncogene homolog
chr10_-_3827418	2.480	NM_001160124 NM_001160125 NM_001300	KLF6	Kruppel-like factor 6
chr3_-_99594915	2.453	NM_014890	FILIP1L	filamin A interacting protein 1-like
chr1_-_16482426	2.421	NM_004431	EPHA2	EPH receptor A2
chr8_+_86376130	2.403	NM_000067	CA2	carbonic anhydrase II
chr16_+_56691854	2.383	NM_005949	MT1F	metallothionein 1F
chr11_-_18270167	2.352	NM_001199744 NM_001127380 NM_030754	SAA2-SAA4 SAA2	SAA2-SAA4 readthrough serum amyloid A2
chr1_-_43424536	2.258		SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1
chr8_-_23261675	2.204	NM_002318	LOXL2	lysyl oxidase-like 2
chr10_+_17271302	2.203		VIM	vimentin
chr1_-_11714471	2.193		FBXO2	F-box protein 2
chr1_-_153044083	2.171	NM_001017418	SPRR2B	small proline-rich protein 2B
chr3_-_49395751	2.139	NM_000581 NM_201397	GPX1	glutathione peroxidase 1
chr21_-_27543445	2.037	NM_001136131	APP	amyloid beta (A4) precursor protein
chr4_-_74964836	2.009		CXCL2	chemokine (C-X-C motif) ligand 2
chr1_-_203155827	1.996		CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)
chr14_+_65007418	1.987		HSPA2	heat shock 70kDa protein 2
chr7_+_94024201	1.969		COL1A2	collagen, type I, alpha 2
chr1_-_152297678	1.905	NM_002016	FLG	filaggrin
chr19_-_6720585	1.902	NM_000064	C3	complement component 3
chr3_+_193853937	1.858		HES1	hairy and enhancer of split 1, (Drosophila)
chr17_-_39538635	1.819	NM_021013	KRT34	keratin 34
chr7_-_94285372	1.815		SGCE	sarcoglycan, epsilon
chr9_+_130911731	1.781	NM_005564	LCN2	lipocalin 2
chr12_-_52685249	1.756	NM_002281	KRT81	keratin 81
chr12_+_13044493	1.716		GPRC5A	G protein-coupled receptor, family C, group 5, member A
chr10_-_3827205	1.714		KLF6	Kruppel-like factor 6
chr7_-_94285426	1.697		SGCE	sarcoglycan, epsilon
chr1_-_86043932	1.689	NM_001134445	DDAH1	dimethylarginine dimethylaminohydrolase 1
chr2_-_122042767	1.681	NM_014553	TFCP2L1	transcription factor CP2-like 1
chr7_-_94285477	1.679	NM_001099400 NM_001099401 NM_003919	SGCE	sarcoglycan, epsilon
chr17_-_10325266	1.644	NM_002472	MYH8	myosin, heavy chain 8, skeletal muscle, perinatal
chr2_-_43453737	1.628	NM_006887	ZFP36L2	zinc finger protein 36, C3H type-like 2
chr7_-_134143804	1.628		AKR1B1	aldo-keto reductase family 1, member B1 (aldose reductase)
chr20_+_30193083	1.613	NM_002165 NM_181353	ID1	inhibitor of DNA binding 1, dominant negative helix-loop-helix protein
chr19_+_676346	1.588	NM_005860	FSTL3	follistatin-like 3 (secreted glycoprotein)
chr6_-_53409897	1.576	NM_001197115 NM_001498	GCLC	glutamate-cysteine ligase, catalytic subunit
chr10_+_17271341	1.557		VIM	vimentin
chr1_-_43424324	1.551		SLC2A1	solute carrier family 2 (facilitated glucose transporter), member 1
chr11_-_111782447	1.537	NM_001885	CRYAB	crystallin, alpha B
chr1_-_27481400	1.528	NM_003047	SLC9A1	solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr17_-_79818406	1.524		P4HB	prolyl 4-hydroxylase, beta polypeptide
chr17_-_48278987	1.462	NM_000088	COL1A1	collagen, type I, alpha 1
chr16_+_56966025	1.450		HERPUD1	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr15_-_85201417	1.435		NMB	neuromedin B
chr13_-_45150601	1.410	NM_001243799 NM_183422	TSC22D1	TSC22 domain family, member 1
chr3_+_193853930	1.391	NM_005524	HES1	hairy and enhancer of split 1, (Drosophila)
chr18_+_21718930	1.387	NM_012189 NM_138643 NM_153768 NM_153769 NM_153770	CABYR	calcium binding tyrosine-(Y)-phosphorylation regulated
chr15_+_63334753	1.382	NM_000366 NM_001018004 NM_001018005 NM_001018006 NM_001018007 NM_001018020	TPM1	tropomyosin 1 (alpha)
chr16_+_89989686	1.361	NM_006086	TUBB3	tubulin, beta 3 class III
chr10_+_91152321	1.356	NM_001548	IFIT1	interferon-induced protein with tetratricopeptide repeats 1
chr8_-_48650683	1.329		CEBPD	CCAAT/enhancer binding protein (C/EBP), delta
chr1_-_153067000	1.319	NM_001024209	SPRR2E	small proline-rich protein 2E
chr9_+_131314669	1.317	NM_001130438 NM_001195532 NM_003127	SPTAN1	spectrin, alpha, non-erythrocytic 1 (alpha-fodrin)
chrX_-_106960268	1.311	NM_004089	TSC22D3	TSC22 domain family, member 3
chr18_+_21719025	1.300		CABYR	calcium binding tyrosine-(Y)-phosphorylation regulated
chr7_+_94285620	1.298	NM_001040152 NM_001184961 NM_001184962 NM_015068	PEG10	paternally expressed 10
chr2_+_85132762	1.278	NM_021103	TMSB10	thymosin beta 10
chr2_-_179672056	1.274	NM_003319 NM_133378 NM_133379 NM_133432 NM_133437	TTN	titin
chr17_+_43225834	1.274		HEXIM1	hexamethylene bis-acetamide inducible 1
chr1_-_153013593	1.263	NM_006945	SPRR2D	small proline-rich protein 2D
chr3_+_101546833	1.250	NM_001005474	NFKBIZ	nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr2_-_43453146	1.222		ZFP36L2	zinc finger protein 36, C3H type-like 2
chr7_-_134143864	1.221	NM_001628	AKR1B1	aldo-keto reductase family 1, member B1 (aldose reductase)
chr4_-_74904329	1.215	NM_002090	CXCL3	chemokine (C-X-C motif) ligand 3
chr7_+_94285676	1.214	NM_001172437 NM_001172438	PEG10	paternally expressed 10
chr11_+_2398543	1.208	NM_004356	CD81	CD81 molecule
chr1_-_203155867	1.196		CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)
chr11_+_75273245	1.195		SERPINH1	serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)
chr19_+_13049413	1.179	NM_004343	CALR	calreticulin
chr17_+_79008945	1.170	NM_001144888 NM_006340 NM_017450 NM_017451	BAIAP2	BAI1-associated protein 2
chr6_+_132129154	1.169	NM_006208	ENPP1	ectonucleotide pyrophosphatase/phosphodiesterase 1
chr8_+_24771276	1.167		NEFM	neurofilament, medium polypeptide
chr7_+_94285736	1.166		PEG10	paternally expressed 10
chr17_+_7387688	1.161	NM_000937	POLR2A	polymerase (RNA) II (DNA directed) polypeptide A, 220kDa
chr12_-_125399146	1.158		UBC	ubiquitin C
chr16_-_4292052	1.154	NM_001098814	SRL	sarcalumenin
chrX_-_133792497	1.139	NM_021796	PLAC1	placenta-specific 1
chr1_-_11714396	1.136		FBXO2	F-box protein 2
chr12_-_125399586	1.134	NM_021009	UBC	ubiquitin C
chr19_+_13049428	1.099		CALR	calreticulin
chr3_+_49449638	1.078	NM_022171	TCTA	T-cell leukemia translocation altered gene
chr17_-_73775822	1.077	NM_005324	H3F3B	H3 histone, family 3B (H3.3B)
chr7_-_45960738	1.077	NM_000598 NM_001013398	IGFBP3	insulin-like growth factor binding protein 3
chr2_+_85766100	1.076	NM_005911	MAT2A	methionine adenosyltransferase II, alpha
chr16_+_71392637	1.073		CALB2	calbindin 2
chr1_-_203155813	1.063		CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)
chr8_+_24771268	1.053	NM_005382	NEFM	neurofilament, medium polypeptide
chr16_+_71392615	1.040	NM_001740 NM_007088	CALB2	calbindin 2
chr22_+_39916563	1.033	NM_001675 NM_182810	ATF4	activating transcription factor 4 (tax-responsive enhancer element B67)
chr12_-_53298765	1.029	NM_002273	KRT8	keratin 8
chr19_+_572568	0.997		BSG	basigin (Ok blood group)
chr17_-_74707000	0.978	NM_001008528 NM_001008529 NM_198530	MXRA7	matrix-remodelling associated 7
chr19_+_13049440	0.968		CALR	calreticulin
chr17_-_39507055	0.967	NM_004138	KRT33A	keratin 33A
chr19_-_51487070	0.964	NM_139277 NM_001207053 NM_001243126 NM_005046	KLK7	kallikrein-related peptidase 7
chr19_+_572575	0.954		BSG	basigin (Ok blood group)
chr19_+_572403	0.952	NM_001728 NM_198589	BSG	basigin (Ok blood group)
chr6_-_133035180	0.923	NM_004666	VNN1	vanin 1
chr6_-_169654047	0.920	NM_003247	THBS2	thrombospondin 2
chr10_-_62703822	0.920	NM_001242359 NM_014836	RHOBTB1	Rho-related BTB domain containing 1
chr2_+_85766291	0.917		MAT2A	methionine adenosyltransferase II, alpha
chr12_-_49582800	0.906	NM_006009	TUBA1A	tubulin, alpha 1a
chr17_-_10560625	0.889	NM_002470	MYH3	myosin, heavy chain 3, skeletal muscle, embryonic
chr9_-_99329092	0.885	NM_001077181	CDC14B	CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr17_+_79008958	0.884		BAIAP2	BAI1-associated protein 2
chr17_-_48278874	0.883		COL1A1	collagen, type I, alpha 1
chr9_+_140135742	0.883		TUBB4B	tubulin, beta 4B class IVb
chr1_+_163038934	0.866	NM_001113381	RGS4	regulator of G-protein signaling 4
chr1_+_153963237	0.860	NM_001030	RPS27	ribosomal protein S27
chr19_+_41222915	0.853	NM_025194	ITPKC	inositol-trisphosphate 3-kinase C
chr11_-_61735067	0.853		FTH1 CPSF7	ferritin, heavy polypeptide 1 cleavage and polyadenylation specific factor 7, 59kDa
chr9_+_140135738	0.851		TUBB4B	tubulin, beta 4B class IVb
chr15_-_35087748	0.830	NM_005159	ACTC1	actin, alpha, cardiac muscle 1
chr6_+_12290528	0.824	NM_001168319 NM_001955	EDN1	endothelin 1
chr14_+_90863365	0.817		CALM1	calmodulin 1 (phosphorylase kinase, delta)
chr14_+_94492747	0.814		OTUB2	OTU domain, ubiquitin aldehyde binding 2
chr6_-_35765056	0.802	NM_001252597 NM_001252598 NM_001832	CLPS	colipase, pancreatic
chr9_-_5437825	0.796	NM_018465	C9orf46	chromosome 9 open reading frame 46
chr12_+_6643967	0.794		GAPDH	glyceraldehyde-3-phosphate dehydrogenase
chr2_-_43453724	0.791		ZFP36L2	zinc finger protein 36, C3H type-like 2
chr9_+_140135698	0.730	NM_006088	TUBB4B	tubulin, beta 4B class IVb
chr1_+_202509241	0.722	NM_001197131	PPP1R12B	protein phosphatase 1, regulatory subunit 12B
chrX_-_106960028	0.721		TSC22D3	TSC22 domain family, member 3
chr1_-_203155910	0.714	NM_001276	CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)
chr1_-_203155745	0.714		CHI3L1	chitinase 3-like 1 (cartilage glycoprotein-39)
chr6_+_31783314	0.677		HSPA1A HSPA1B	heat shock 70kDa protein 1A heat shock 70kDa protein 1B
chr4_-_169239816	0.670	NM_017631	DDX60	DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chr1_-_228613025	0.669	NM_003493	HIST3H3	histone cluster 3, H3
chr10_+_17851342	0.669	NM_002438	MRC1	mannose receptor, C type 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
4.55	4.39e-10	GO:0009888	tissue development
9.44	4.15e-08	GO:0008544	epidermis development
2.05	7.04e-07	GO:0032502	developmental process
2.18	9.39e-07	GO:0048856	anatomical structure development
5.91	2.73e-05	GO:0010035	response to inorganic substance
2.51	3.23e-05	GO:0048513	organ development
26.75	5.54e-05	GO:0031424	keratinization
2.11	6.07e-05	GO:0048731	system development
2.15	5.91e-04	GO:0042221	response to chemical stimulus
1.68	6.33e-04	GO:0032501	multicellular organismal process
2.98	1.66e-03	GO:0009611	response to wounding
1.86	1.77e-03	GO:0007275	multicellular organismal development
15.49	1.79e-03	GO:0030193	regulation of blood coagulation
14.36	2.85e-03	GO:0050818	regulation of coagulation
13.38	4.37e-03	GO:0030216	keratinocyte differentiation
2.00	5.20e-03	GO:0006950	response to stress
4.81	6.15e-03	GO:0006954	inflammatory response
12.52	6.48e-03	GO:0061041	regulation of wound healing
2.93	6.62e-03	GO:0040011	locomotion
5.78	7.58e-03	GO:0006979	response to oxidative stress
2.96	9.55e-03	GO:0051128	regulation of cellular component organization
2.11	1.13e-02	GO:0048869	cellular developmental process
11.32	1.18e-02	GO:0009913	epidermal cell differentiation
2.10	1.69e-02	GO:0030154	cell differentiation
7.99	2.26e-02	GO:0000302	response to reactive oxygen species
3.42	2.62e-02	GO:0006935	chemotaxis
3.42	2.62e-02	GO:0042330	taxis
2.83	3.04e-02	GO:0006952	defense response
20.65	3.06e-02	GO:0045103	intermediate filament-based process
2.26	3.41e-02	GO:0009653	anatomical structure morphogenesis
12.58	3.81e-02	GO:0034614	cellular response to reactive oxygen species
3.50	3.82e-02	GO:0007010	cytoskeleton organization
3.47	4.15e-02	GO:0072358	cardiovascular system development
3.47	4.15e-02	GO:0072359	circulatory system development
18.68	4.66e-02	GO:0018149	peptide cross-linking

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
19.62	9.68e-15	GO:0005882	intermediate filament
15.54	4.82e-13	GO:0045111	intermediate filament cytoskeleton
3.36	5.45e-10	GO:0005856	cytoskeleton
4.14	1.07e-08	GO:0005615	extracellular space
3.52	9.95e-08	GO:0044421	extracellular region part
23.78	1.33e-07	GO:0045095	keratin filament
2.69	4.20e-07	GO:0005576	extracellular region
34.61	1.45e-06	GO:0001533	cornified envelope
3.20	2.26e-05	GO:0044430	cytoskeletal part
2.03	2.03e-04	GO:0043228	non-membrane-bounded organelle
2.03	2.03e-04	GO:0043232	intracellular non-membrane-bounded organelle
3.98	6.13e-03	GO:0031012	extracellular matrix
98.05	1.37e-02	GO:0005584	collagen type I
10.44	1.44e-02	GO:0031093	platelet alpha granule lumen
10.22	1.60e-02	GO:0034774	secretory granule lumen
9.81	1.95e-02	GO:0060205	cytoplasmic membrane-bounded vesicle lumen
9.44	2.35e-02	GO:0031983	vesicle lumen
8.76	3.34e-02	GO:0031091	platelet alpha granule
3.79	4.00e-02	GO:0015629	actin cytoskeleton

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
6.21	4.03e-15	GO:0005198	structural molecule activity
16.82	6.21e-10	GO:0005200	structural constituent of cytoskeleton
78.44	6.99e-06	GO:0046870	cadmium ion binding
12.80	9.04e-04	GO:0005507	copper ion binding
1.37	5.56e-03	GO:0005515	protein binding
29.42	1.63e-02	GO:0001968	fibronectin binding
26.75	2.22e-02	GO:0048407	platelet-derived growth factor binding
3.58	3.44e-02	GO:0030246	carbohydrate binding