Motif ID: TCF4_dimer.p2

Z-value: 2.144


Transcription factors associated with TCF4_dimer.p2:

Gene SymbolEntrez IDGene Name
TCF4 6925 transcription factor 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
TCF4chr18_-_530712250.411.2e-01Click!


Activity profile for motif TCF4_dimer.p2.

activity profile for motif TCF4_dimer.p2


Sorted Z-values histogram for motif TCF4_dimer.p2

Sorted Z-values for motif TCF4_dimer.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of TCF4_dimer.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr15_+_74218962 6.887 LOXL1
lysyl oxidase-like 1
chr9_-_35689799 4.825 TPM2
tropomyosin 2 (beta)
chr9_-_35689902 4.746 NM_003289
NM_213674
TPM2

tropomyosin 2 (beta)

chr2_+_220283098 4.632 NM_001927
DES
desmin
chr4_-_80994183 4.587


chr15_+_74218786 4.435 NM_005576
LOXL1
lysyl oxidase-like 1
chr15_+_74218794 4.372 LOXL1
lysyl oxidase-like 1
chr15_-_48937795 3.928 NM_000138
FBN1
fibrillin 1
chr9_-_75567915 3.771 ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr2_+_170366211 3.659 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr7_+_94023872 3.418 NM_000089
COL1A2
collagen, type I, alpha 2
chr9_-_75568232 3.200 NM_000689
ALDH1A1
aldehyde dehydrogenase 1 family, member A1
chr7_+_94024201 3.143 COL1A2
collagen, type I, alpha 2
chr10_+_124220990 2.978 NM_002775
HTRA1
HtrA serine peptidase 1
chr2_-_175629140 2.835 NM_000079
NM_001039523
CHRNA1

cholinergic receptor, nicotinic, alpha 1 (muscle)

chr3_-_87040246 2.748 NM_016206
VGLL3
vestigial like 3 (Drosophila)
chr11_-_47470687 2.728 NM_005055
NM_032645
RAPSN

receptor-associated protein of the synapse

chr6_-_139695349 2.565 NM_001168389
NM_001168388
CITED2

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2

chrX_-_135863502 2.539 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chrX_-_107018889 2.518 TSC22D3
TSC22 domain family, member 3
chr12_+_81110689 2.434 NM_005593
MYF5
myogenic factor 5
chr17_+_45286713 2.429 NM_002476
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr3_+_35681008 2.424 ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr7_+_102553343 2.409 NM_001031692
NM_005824
LRRC17

leucine rich repeat containing 17

chr10_-_92681025 2.403 NM_014391
ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr10_+_11060069 2.398 CELF2
CUGBP, Elav-like family member 2
chr10_+_31608097 2.392 NM_001174093
NM_001174095
NM_001174096
NM_030751
ZEB1



zinc finger E-box binding homeobox 1



chr2_-_192711923 2.384 NM_004657
SDPR
serum deprivation response
chr8_-_49833823 2.378 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr11_+_65779461 2.373 NM_001323
CST6
cystatin E/M
chr12_-_91505215 2.360 LUM
lumican
chr21_+_30517897 2.316 C21orf7
chromosome 21 open reading frame 7
chr15_+_74218811 2.302 LOXL1
lysyl oxidase-like 1
chr7_-_131241321 2.294 NM_001018111
NM_005397
PODXL

podocalyxin-like

chr2_-_192711651 2.284 SDPR
serum deprivation response
chr12_-_91505541 2.276 NM_002345
LUM
lumican
chr10_+_11059854 2.246 NM_006561
CELF2
CUGBP, Elav-like family member 2
chr4_-_41216455 2.217 NM_001166050
NM_004307
NM_173075
APBB2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr1_-_201346804 2.215 NM_000364
NM_001001430
NM_001001431
NM_001001432
TNNT2



troponin T type 2 (cardiac)



chr10_+_31607419 2.165 ZEB1
zinc finger E-box binding homeobox 1
chr2_-_37899227 2.153 NM_006449
CDC42EP3
CDC42 effector protein (Rho GTPase binding) 3
chr7_-_45960738 2.141 NM_000598
NM_001013398
IGFBP3

insulin-like growth factor binding protein 3

chr10_-_92680784 2.134 ANKRD1
ankyrin repeat domain 1 (cardiac muscle)
chr1_-_201346783 2.094 TNNT2
troponin T type 2 (cardiac)
chr15_-_35087748 2.049 NM_005159
ACTC1
actin, alpha, cardiac muscle 1
chr7_+_98246595 2.048 NM_002523
NPTX2
neuronal pentraxin II
chr7_+_116140097 2.029 NM_001206748
CAV2
caveolin 2
chrX_-_13956530 2.019 GPM6B
glycoprotein M6B
chr1_-_33168356 2.012 NM_001161708
NM_030786
SYNC

syncoilin, intermediate filament protein

chr2_-_211179765 1.978 NM_079420
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr5_+_148520985 1.958 NM_014945
ABLIM3
actin binding LIM protein family, member 3
chrX_+_70521627 1.950 NM_012278
ITGB1BP2
integrin beta 1 binding protein (melusin) 2
chr4_+_41258941 1.949 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr10_+_104404195 1.894 NM_030912
TRIM8
tripartite motif containing 8
chr10_+_11060105 1.893 CELF2
CUGBP, Elav-like family member 2
chr10_+_11207053 1.888 CELF2
CUGBP, Elav-like family member 2
chr19_-_45826131 1.859 CKM
creatine kinase, muscle
chr10_-_75410778 1.845 NM_024875
SYNPO2L
synaptopodin 2-like
chr2_-_190044330 1.802 NM_000393
COL5A2
collagen, type V, alpha 2
chr11_-_63933493 1.795 NM_014067
MACROD1
MACRO domain containing 1
chr12_+_78225068 1.795 NM_014903
NAV3
neuron navigator 3
chr3_+_8775485 1.788 NM_001234
NM_033337
CAV3

caveolin 3

chrX_-_107019001 1.765 NM_198057
TSC22D3
TSC22 domain family, member 3
chr6_-_139695739 1.748 CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr21_+_27011588 1.746 NM_021219
JAM2
junctional adhesion molecule 2
chr17_+_45286427 1.682 NM_001002841
MYL4
myosin, light chain 4, alkali; atrial, embryonic
chr6_-_139695784 1.673 NM_006079
CITED2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr1_-_95392501 1.668 NM_001839
CNN3
calponin 3, acidic
chr1_+_182992694 1.656


chr1_-_193155723 1.653 NM_003783
B3GALT2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr17_-_10452939 1.651 NM_001100112
NM_017534
MYH2

myosin, heavy chain 2, skeletal muscle, adult

chr2_-_179672056 1.626 NM_003319
NM_133378
NM_133379
NM_133432
NM_133437
TTN




titin




chr1_-_144931707 1.614 PDE4DIP
phosphodiesterase 4D interacting protein
chr9_-_97401588 1.611 FBP1
fructose-1,6-bisphosphatase 1
chr8_+_22436641 1.598 PDLIM2
PDZ and LIM domain 2 (mystique)
chr11_-_63933204 1.597 MACROD1
MACRO domain containing 1
chr4_-_57976516 1.594 IGFBP7
insulin-like growth factor binding protein 7
chr8_-_41522724 1.588 NM_001142445
NM_020478
NM_020480
ANK1


ankyrin 1, erythrocytic


chr10_+_11206928 1.572 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr21_-_39288661 1.569 NM_002240
KCNJ6
potassium inwardly-rectifying channel, subfamily J, member 6
chr4_-_57976550 1.561 NM_001253835
NM_001553
IGFBP7

insulin-like growth factor binding protein 7

chr4_-_157892545 1.557 NM_016205
PDGFC
platelet derived growth factor C
chr21_-_44845920 1.544 SIK1
salt-inducible kinase 1
chr15_+_63340314 1.544 NM_001018008
TPM1
tropomyosin 1 (alpha)
chr4_-_57976355 1.519 IGFBP7
insulin-like growth factor binding protein 7
chr1_+_223889253 1.518 NM_001146068
CAPN2
calpain 2, (m/II) large subunit
chr2_+_71295685 1.509 NAGK
N-acetylglucosamine kinase
chrX_-_13956644 1.468 NM_001001994
GPM6B
glycoprotein M6B
chr11_+_1886394 1.457 NM_001242932
LSP1
lymphocyte-specific protein 1
chr19_-_46974663 1.441 PNMAL1
PNMA-like 1
chr6_-_137113166 1.439


chr3_-_178789535 1.427 ZMAT3
zinc finger, matrin-type 3
chr2_-_152590983 1.412 NM_001164507
NM_001164508
NM_004543
NEB


nebulin


chr1_-_85930610 1.411 DDAH1
dimethylarginine dimethylaminohydrolase 1
chr11_-_119294242 1.408 NM_006288
THY1
Thy-1 cell surface antigen
chr22_-_19511777 1.404 CLDN5
claudin 5
chr3_-_178789597 1.381 NM_022470
NM_152240
ZMAT3

zinc finger, matrin-type 3

chrX_-_135863033 1.368 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr5_-_88199868 1.367 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr11_+_86511490 1.362 NM_007173
PRSS23
protease, serine, 23
chr15_-_26108236 1.359 NM_024490
ATP10A
ATPase, class V, type 10A
chrX_-_135863104 1.359 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr7_+_116166346 1.337 NM_001172896
NM_001172897
CAV1

caveolin 1, caveolae protein, 22kDa

chr11_-_119293848 1.304 THY1
Thy-1 cell surface antigen
chr11_+_1860232 1.290 NM_003282
TNNI2
troponin I type 2 (skeletal, fast)
chr5_-_172755195 1.284 STC2
stanniocalcin 2
chr2_+_223916861 1.280 NM_080671
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr1_-_203144910 1.268 NM_004997
MYBPH
myosin binding protein H
chr19_-_12886263 1.228 HOOK2
hook homolog 2 (Drosophila)
chr3_+_158787040 1.222 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr6_+_129204285 1.222 NM_000426
NM_001079823
LAMA2

laminin, alpha 2

chr7_+_44788453 1.211 NM_031449
ZMIZ2
zinc finger, MIZ-type containing 2
chr8_+_1922030 1.192 NM_014867
KBTBD11
kelch repeat and BTB (POZ) domain containing 11
chr4_-_157892054 1.187 PDGFC
platelet derived growth factor C
chr5_+_140864626 1.177 NM_018928
NM_032406
PCDHGC4

protocadherin gamma subfamily C, 4

chr7_-_37956377 1.164 SFRP4
secreted frizzled-related protein 4
chr5_-_151066492 1.159 NM_003118
SPARC
secreted protein, acidic, cysteine-rich (osteonectin)
chr3_-_99833348 1.153 NM_001042459
NM_182909
FILIP1L

filamin A interacting protein 1-like

chr3_-_15900928 1.138 NM_015199
ANKRD28
ankyrin repeat domain 28
chr16_-_31076408 1.132 NM_001172669
NM_001172670
ZNF668

zinc finger protein 668

chr5_-_176899870 1.131 NM_080881
DBN1
drebrin 1
chr16_+_7382750 1.129 NM_145891
NM_145892
NM_145893
RBFOX1


RNA binding protein, fox-1 homolog (C. elegans) 1


chr19_-_49658645 1.120 NM_002152
HRC
histidine rich calcium binding protein
chr1_+_145524989 1.119 NM_003637
ITGA10
integrin, alpha 10
chr19_-_18717577 1.116 CRLF1
cytokine receptor-like factor 1
chr14_-_23821423 1.103 NM_020372
SLC22A17
solute carrier family 22, member 17
chr6_+_57037058 1.083 NM_004282
BAG2
BCL2-associated athanogene 2
chr6_+_46097700 1.081 NM_014936
ENPP4
ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
chr11_-_6341708 1.081 NM_145040
PRKCDBP
protein kinase C, delta binding protein
chrX_+_135251454 1.076 NM_001159704
FHL1
four and a half LIM domains 1
chr1_-_40367539 1.075 NM_001033081
NM_001033082
NM_005376
MYCL1


v-myc myelocytomatosis viral oncogene homolog 1, lung carcinoma derived (avian)


chr6_-_46459010 1.075 NM_001251974
RCAN2
regulator of calcineurin 2
chr6_-_137113624 1.070 NM_005923
MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr11_+_69455837 1.067 NM_053056
CCND1
cyclin D1
chr1_-_23885916 1.066 ID3
inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
chr1_-_147931877 1.048 FLJ39739
uncharacterized FLJ39739
chr15_-_42749710 1.042 NM_022473
ZFP106
zinc finger protein 106 homolog (mouse)
chr19_-_18717631 1.033 NM_004750
CRLF1
cytokine receptor-like factor 1
chr12_+_122150638 1.025 NM_001080825
TMEM120B
transmembrane protein 120B
chr1_-_17445865 1.007 NM_007365
PADI2
peptidyl arginine deiminase, type II
chr21_+_47531369 1.006 COL6A2
collagen, type VI, alpha 2
chr11_-_64014381 1.001 PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chrX_-_6146655 1.001 NM_181332
NLGN4X
neuroligin 4, X-linked
chr6_+_46097818 0.993 ENPP4
ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
chr19_-_11308184 0.972 NM_001136191
KANK2
KN motif and ankyrin repeat domains 2
chr6_-_137113602 0.959 MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr6_-_137113721 0.954 MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr9_+_133320093 0.953 NM_000050
NM_054012
ASS1

argininosuccinate synthase 1

chr10_+_17271341 0.949 VIM
vimentin
chr1_+_86046434 0.948 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr9_+_34990715 0.939 DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr4_-_186733372 0.934 NM_003603
NM_001145670
SORBS2

sorbin and SH3 domain containing 2

chr11_+_1860718 0.928 NM_001145829
TNNI2
troponin I type 2 (skeletal, fast)
chr11_+_44587140 0.927 NM_001024844
NM_002231
CD82

CD82 molecule

chr5_+_95066628 0.926 NM_014899
RHOBTB3
Rho-related BTB domain containing 3
chr1_-_109584589 0.923 NM_001142550
NM_001142551
NM_014969
WDR47


WD repeat domain 47


chr19_-_12886421 0.919 NM_001100176
NM_013312
HOOK2

hook homolog 2 (Drosophila)

chr17_+_16945766 0.909 NM_015134
NM_201274
MPRIP

myosin phosphatase Rho interacting protein

chr15_-_23932364 0.908


chr2_-_1748317 0.907 PXDN
peroxidasin homolog (Drosophila)
chr5_+_71403040 0.907 NM_005909
MAP1B
microtubule-associated protein 1B
chr15_-_56209305 0.907 NM_198400
NEDD4
neural precursor cell expressed, developmentally down-regulated 4
chr6_-_137113529 0.906 MAP3K5
mitogen-activated protein kinase kinase kinase 5
chr8_+_22436253 0.894 NM_021630
PDLIM2
PDZ and LIM domain 2 (mystique)
chr11_+_67776016 0.885 NM_001161473
ALDH3B1
aldehyde dehydrogenase 3 family, member B1
chrX_-_13956445 0.884


chr12_-_110434028 0.879 GIT2
G protein-coupled receptor kinase interacting ArfGAP 2
chr2_-_230135954 0.878 NM_001100818
NM_017933
PID1

phosphotyrosine interaction domain containing 1

chr19_-_18717467 0.877 CRLF1
cytokine receptor-like factor 1
chr10_+_17271956 0.868 VIM
vimentin
chr2_-_1748240 0.868 PXDN
peroxidasin homolog (Drosophila)
chr17_-_48264039 0.866 COL1A1
collagen, type I, alpha 1
chr6_-_46293404 0.865 RCAN2
regulator of calcineurin 2
chr19_-_45826232 0.864 NM_001824
CKM
creatine kinase, muscle
chr10_+_17271859 0.860 VIM
vimentin
chr14_-_34419957 0.859 NM_022073
EGLN3
egl nine homolog 3 (C. elegans)
chr11_+_44587212 0.854 CD82
CD82 molecule
chr9_-_97401746 0.851 FBP1
fructose-1,6-bisphosphatase 1
chr9_+_34990266 0.850 NM_001135005
DNAJB5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr2_+_238395863 0.845 NM_001042467
NM_024101
MLPH

melanophilin

chr6_-_24911194 0.844 NM_014722
FAM65B
family with sequence similarity 65, member B
chr17_+_7348362 0.842 NM_000747
CHRNB1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr12_+_6833425 0.842 NM_001164093
COPS7A
COP9 constitutive photomorphogenic homolog subunit 7A (Arabidopsis)
chr8_-_17941598 0.839 ASAH1
N-acylsphingosine amidohydrolase (acid ceramidase) 1
chr11_-_35547144 0.836 NM_001001991
NM_015430
PAMR1

peptidase domain containing associated with muscle regeneration 1

chr15_+_83776323 0.831 NM_001144903
NM_023003
TM6SF1

transmembrane 6 superfamily member 1

chr17_+_1665233 0.826 NM_002615
SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr10_-_62703822 0.824 NM_001242359
NM_014836
RHOBTB1

Rho-related BTB domain containing 1

chr16_+_89238160 0.820 NM_004933
CDH15
cadherin 15, type 1, M-cadherin (myotubule)
chr17_+_1665281 0.812 SERPINF1
serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
chr11_-_61658853 0.806 NM_021727
FADS3
fatty acid desaturase 3
chr8_+_37654833 0.806 GPR124
G protein-coupled receptor 124
chr17_+_68165660 0.804 NM_000891
KCNJ2
potassium inwardly-rectifying channel, subfamily J, member 2
chr1_+_203097427 0.802 ADORA1
adenosine A1 receptor
chr1_+_89990396 0.797 NM_001134476
LRRC8B
leucine rich repeat containing 8 family, member B
chr12_-_111358353 0.792 NM_000432
MYL2
myosin, light chain 2, regulatory, cardiac, slow
chr9_-_89562103 0.788 NM_002048
GAS1
growth arrest-specific 1
chr19_-_46285645 0.788 DMPK
dystrophia myotonica-protein kinase
chr17_+_7348840 0.787 CHRNB1
cholinergic receptor, nicotinic, beta 1 (muscle)
chr10_+_99258615 0.787 NM_024954
UBTD1
ubiquitin domain containing 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
35.15 4.44e-12 GO:0030049 muscle filament sliding
35.15 4.44e-12 GO:0033275 actin-myosin filament sliding
34.23 6.21e-12 GO:0070252 actin-mediated cell contraction
25.50 2.24e-10 GO:0030048 actin filament-based movement
11.61 2.85e-10 GO:0007517 muscle organ development
11.52 1.82e-09 GO:0006936 muscle contraction
8.71 5.50e-09 GO:0061061 muscle structure development
10.56 6.49e-09 GO:0003012 muscle system process
26.28 3.35e-07 GO:0006941 striated muscle contraction
10.20 3.16e-05 GO:0042692 muscle cell differentiation
6.33 8.55e-05 GO:0030029 actin filament-based process
16.56 1.26e-04 GO:0055001 muscle cell development
23.65 1.23e-03 GO:0031032 actomyosin structure organization
15.77 1.33e-03 GO:0055002 striated muscle cell development
11.66 1.46e-03 GO:0051146 striated muscle cell differentiation
8.93 2.05e-03 GO:0014706 striated muscle tissue development
8.16 4.03e-03 GO:0060537 muscle tissue development
31.53 4.15e-03 GO:0043462 regulation of ATPase activity
31.53 4.15e-03 GO:0060048 cardiac muscle contraction
1.68 4.92e-03 GO:0032501 multicellular organismal process
2.61 6.73e-03 GO:0003008 system process
59.11 7.82e-03 GO:0031579 membrane raft organization
1.92 8.51e-03 GO:0048856 anatomical structure development
24.89 1.15e-02 GO:0003015 heart process
24.89 1.15e-02 GO:0030239 myofibril assembly
24.89 1.15e-02 GO:0060047 heart contraction
1.84 1.80e-02 GO:0007275 multicellular organismal development
4.59 1.84e-02 GO:0044057 regulation of system process
2.23 2.04e-02 GO:0048513 organ development
3.01 2.86e-02 GO:0009888 tissue development
1.91 3.06e-02 GO:0048731 system development
39.41 3.22e-02 GO:0045214 sarcomere organization
9.10 3.36e-02 GO:0008016 regulation of heart contraction
35.47 4.58e-02 GO:0032781 positive regulation of ATPase activity
118.21 4.80e-02 GO:0001765 membrane raft assembly
118.21 4.80e-02 GO:0070836 caveola assembly

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
19.33 1.52e-15 GO:0030016 myofibril
22.00 1.67e-15 GO:0030017 sarcomere
18.11 4.81e-15 GO:0043292 contractile fiber
18.73 2.49e-14 GO:0044449 contractile fiber part
7.77 6.75e-09 GO:0015629 actin cytoskeleton
23.07 2.03e-07 GO:0031674 I band
45.47 6.43e-06 GO:0005865 striated muscle thin filament
22.17 3.22e-05 GO:0030018 Z disc
2.60 9.22e-04 GO:0005856 cytoskeleton
2.78 9.61e-03 GO:0044430 cytoskeletal part
10.95 1.20e-02 GO:0016459 myosin complex
32.25 1.24e-02 GO:0005583 fibrillar collagen
7.25 2.38e-02 GO:0044420 extracellular matrix part
4.00 2.67e-02 GO:0031012 extracellular matrix
1.82 4.90e-02 GO:0043228 non-membrane-bounded organelle
1.82 4.90e-02 GO:0043232 intracellular non-membrane-bounded organelle

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
4.92 1.55e-07 GO:0005198 structural molecule activity
23.07 2.07e-07 GO:0008307 structural constituent of muscle
4.81 3.89e-06 GO:0008092 cytoskeletal protein binding
5.68 6.10e-05 GO:0003779 actin binding
8.70 3.68e-02 GO:0005201 extracellular matrix structural constituent