Motif ID: ZNF384.p2

Z-value: 1.526


Transcription factors associated with ZNF384.p2:

Gene SymbolEntrez IDGene Name
ZNF384 171017 zinc finger protein 384

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZNF384chr12_-_67984190.524.1e-02Click!


Activity profile for motif ZNF384.p2.

activity profile for motif ZNF384.p2


Sorted Z-values histogram for motif ZNF384.p2

Sorted Z-values for motif ZNF384.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZNF384.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_189839113 7.197 COL3A1
collagen, type III, alpha 1
chr2_+_189839078 6.833 NM_000090
COL3A1
collagen, type III, alpha 1
chr2_+_189839132 5.721 COL3A1
collagen, type III, alpha 1
chr2_-_190044330 4.636 NM_000393
COL5A2
collagen, type V, alpha 2
chr2_-_238322770 3.681 COL6A3
collagen, type VI, alpha 3
chr4_+_55095263 3.604 NM_006206
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr2_-_238322840 3.401 NM_004369
NM_057164
NM_057165
NM_057166
NM_057167
COL6A3




collagen, type VI, alpha 3




chr12_-_91505541 3.236 NM_002345
LUM
lumican
chr2_-_175712276 3.161 NM_001206602
CHN1
chimerin (chimaerin) 1
chr2_+_170366211 2.716 NM_006063
KBTBD10
kelch repeat and BTB (POZ) domain containing 10
chr2_-_188419185 2.694 NM_001032281
NM_006287
TFPI

tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)

chr2_-_238322815 2.667 COL6A3
collagen, type VI, alpha 3
chr2_-_190927321 2.650 NM_005259
MSTN
myostatin
chr13_+_102104941 2.558 NM_004791
ITGBL1
integrin, beta-like 1 (with EGF-like repeat domains)
chr12_-_91576805 2.446 NM_001920
DCN
decorin
chrX_-_135863502 2.186 NM_004840
ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr3_-_55521567 2.109 WNT5A
wingless-type MMTV integration site family, member 5A
chr10_+_11207053 2.054 CELF2
CUGBP, Elav-like family member 2
chr2_-_217560247 2.007 NM_000599
IGFBP5
insulin-like growth factor binding protein 5
chr2_-_145277879 2.004 NM_001171653
NM_014795
ZEB2

zinc finger E-box binding homeobox 2

chr1_-_57045235 1.990 NM_003713
PPAP2B
phosphatidic acid phosphatase type 2B
chr1_+_196621007 1.879 NM_000186
NM_001014975
CFH

complement factor H

chr2_-_188419049 1.802 TFPI
tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)
chr10_+_70847817 1.753 NM_002727
SRGN
serglycin
chr1_-_103574051 1.706 NM_001190709
NM_001854
NM_080629
NM_080630
COL11A1



collagen, type XI, alpha 1



chr2_-_211179765 1.667 NM_079420
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr3_-_55521330 1.624 NM_003392
WNT5A
wingless-type MMTV integration site family, member 5A
chr12_-_91576579 1.611 DCN
decorin
chr4_-_80994183 1.568


chr5_-_42811959 1.511 NM_001085486
NM_001093726
NM_005410
SEPP1


selenoprotein P, plasma, 1


chr6_-_46293404 1.488 RCAN2
regulator of calcineurin 2
chr2_-_224467049 1.452 SCG2
secretogranin II
chr4_+_41700736 1.448 LIMCH1
LIM and calponin homology domains 1
chr11_-_27681195 1.433 NM_001143816
NM_170735
BDNF

brain-derived neurotrophic factor

chr1_+_164528586 1.393 NM_001204961
NM_001204963
NM_002585
PBX1


pre-B-cell leukemia homeobox 1


chr20_+_9288446 1.317 NM_000933
PLCB4
phospholipase C, beta 4
chr2_-_224467142 1.316 NM_003469
SCG2
secretogranin II
chr4_+_41258941 1.315 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr5_+_155753755 1.313 NM_000337
NM_001128209
NM_172244
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr2_-_224467095 1.292 SCG2
secretogranin II
chr2_-_163099877 1.288 NM_004460
FAP
fibroblast activation protein, alpha
chr3_+_69985750 1.280 NM_000248
NM_001184968
NM_198158
NM_198178
MITF



microphthalmia-associated transcription factor



chr4_+_41258909 1.261 UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr4_+_41258895 1.254 NM_004181
UCHL1
ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
chr20_-_35274557 1.246 NM_032214
NM_175077
SLA2

Src-like-adaptor 2

chr5_-_88119604 1.214 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr1_+_51434447 1.213 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr2_+_5832778 1.209 NM_003108
SOX11
SRY (sex determining region Y)-box 11
chr12_-_56106061 1.192 NM_001144997
ITGA7
integrin, alpha 7
chr5_-_149535138 1.191 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr5_+_155754172 1.186 SGCD
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
chr7_-_137028433 1.167 PTN
pleiotrophin
chr2_+_74120132 1.163 ACTG2
actin, gamma 2, smooth muscle, enteric
chr8_-_12973752 1.158 NM_001164271
DLC1
deleted in liver cancer 1
chr1_+_101185195 1.147 NM_001078
NM_001199834
NM_080682
VCAM1


vascular cell adhesion molecule 1


chr2_+_74120092 1.146 NM_001199893
NM_001615
ACTG2

actin, gamma 2, smooth muscle, enteric

chr12_+_81110689 1.138 NM_005593
MYF5
myogenic factor 5
chr5_+_35856990 1.135 NM_002185
IL7R
interleukin 7 receptor
chr1_+_164818083 1.117 PBX1
pre-B-cell leukemia homeobox 1
chr5_+_125758818 1.115 NM_001146320
NM_001146321
NM_023927
GRAMD3


GRAM domain containing 3


chr13_+_76334796 1.108 NM_015842
LMO7
LIM domain 7
chr3_-_55515361 1.094 WNT5A
wingless-type MMTV integration site family, member 5A
chr2_-_145277568 1.077 ZEB2
zinc finger E-box binding homeobox 2
chr6_-_46293628 1.057 NM_005822
RCAN2
regulator of calcineurin 2
chr10_+_11206928 1.046 NM_001025076
NM_001083591
CELF2

CUGBP, Elav-like family member 2

chr5_-_149535420 1.023 NM_002609
PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr1_-_103573894 1.023 COL11A1
collagen, type XI, alpha 1
chr3_-_123339178 0.990 MYLK
myosin light chain kinase
chr3_-_123339423 0.980 NM_053031
NM_053032
MYLK

myosin light chain kinase

chr4_+_71587674 0.970 NM_001037442
NM_014961
RUFY3

RUN and FYVE domain containing 3

chr5_-_39424930 0.966 DAB2
disabled homolog 2, mitogen-responsive phosphoprotein (Drosophila)
chr20_-_34025955 0.944 NM_000557
GDF5
growth differentiation factor 5
chr21_-_28339405 0.942 NM_007038
ADAMTS5
ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr17_-_46687925 0.938 HOXB7
homeobox B7
chr2_-_231989755 0.931 NM_000867
HTR2B
5-hydroxytryptamine (serotonin) receptor 2B
chr3_-_114790221 0.931 NM_001164343
ZBTB20
zinc finger and BTB domain containing 20
chr7_-_37956377 0.925 SFRP4
secreted frizzled-related protein 4
chr5_-_146833150 0.923 NM_001387
DPYSL3
dihydropyrimidinase-like 3
chr3_+_45067750 0.919 NM_003278
CLEC3B
C-type lectin domain family 3, member B
chr2_+_33359607 0.894 NM_000627
NM_001166264
NM_001166265
NM_001166266
LTBP1



latent transforming growth factor beta binding protein 1



chr3_+_147127151 0.876 NM_003412
ZIC1
Zic family member 1
chr18_-_53089722 0.876 NM_001243233
TCF4
transcription factor 4
chr1_-_57045214 0.857 PPAP2B
phosphatidic acid phosphatase type 2B
chr3_-_120169493 0.823 NM_007085
FSTL1
follistatin-like 1
chr19_-_45996470 0.801 NM_206901
RTN2
reticulon 2
chrX_-_11284094 0.797 NM_013423
ARHGAP6
Rho GTPase activating protein 6
chr10_-_90750955 0.768 NM_001141945
ACTA2
actin, alpha 2, smooth muscle, aorta
chr2_+_30454396 0.748 NM_030915
LBH
limb bud and heart development homolog (mouse)
chr8_-_120651019 0.740 NM_001040092
NM_001130863
NM_006209
ENPP2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr5_+_125759076 0.729 GRAMD3
GRAM domain containing 3
chr1_+_77747727 0.725 AK5
adenylate kinase 5
chr4_+_72204769 0.719 NM_003759
SLC4A4
solute carrier family 4, sodium bicarbonate cotransporter, member 4
chr9_-_16727887 0.711 BNC2
basonuclin 2
chr5_+_92918924 0.710 NM_005654
NR2F1
nuclear receptor subfamily 2, group F, member 1
chr12_+_6898705 0.708 CD4
CD4 molecule
chr17_-_46622274 0.708 NM_002145
HOXB2
homeobox B2
chrX_+_9431314 0.707 NM_001139466
NM_001139467
NM_001139468
TBL1X


transducin (beta)-like 1X-linked


chr12_+_81101407 0.703 NM_002469
MYF6
myogenic factor 6 (herculin)
chr5_+_32711437 0.699 NM_000908
NM_001204375
NPR3

natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)

chr1_+_86046434 0.699 NM_001554
CYR61
cysteine-rich, angiogenic inducer, 61
chr1_-_85155885 0.697 NM_001166295
NM_001166417
NM_001166293
NM_001166294
NM_014021
SSX2IP




synovial sarcoma, X breakpoint 2 interacting protein




chr1_+_162602198 0.692 NM_001014796
NM_006182
DDR2

discoidin domain receptor tyrosine kinase 2

chr3_+_158787040 0.680 NM_001197113
NM_001197114
NM_001042705
NM_001042706
NM_001197100
IQCJ-SCHIP1

IQCJ


IQCJ-SCHIP1 readthrough

IQ motif containing J


chr7_+_94023872 0.676 NM_000089
COL1A2
collagen, type I, alpha 2
chr1_+_51434231 0.676 NM_001262
CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr10_+_91152321 0.676 NM_001548
IFIT1
interferon-induced protein with tetratricopeptide repeats 1
chr3_-_114478117 0.672 NM_001164344
NM_001164345
ZBTB20

zinc finger and BTB domain containing 20

chr16_+_6823809 0.669 NM_001142334
RBFOX1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr2_+_152214105 0.667 NM_007115
TNFAIP6
tumor necrosis factor, alpha-induced protein 6
chr4_+_55095433 0.661 PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr5_+_125800786 0.661 NM_001146322
GRAMD3
GRAM domain containing 3
chr12_+_75874512 0.660 NM_006851
GLIPR1
GLI pathogenesis-related 1
chrX_+_99899162 0.652 NM_014467
SRPX2
sushi-repeat containing protein, X-linked 2
chr17_+_4854383 0.649 NM_001193503
NM_001976
NM_053013
ENO3


enolase 3 (beta, muscle)


chr1_+_162602308 0.641 DDR2
discoidin domain receptor tyrosine kinase 2
chr1_-_57045129 0.640 PPAP2B
phosphatidic acid phosphatase type 2B
chr9_-_88714486 0.639 NM_016548
GOLM1
golgi membrane protein 1
chr2_-_152590983 0.632 NM_001164507
NM_001164508
NM_004543
NEB


nebulin


chr9_-_16870719 0.632 NM_017637
BNC2
basonuclin 2
chr7_+_120628867 0.625 C7orf58
chromosome 7 open reading frame 58
chr7_+_94024201 0.623 COL1A2
collagen, type I, alpha 2
chr7_-_37956515 0.619 NM_003014
SFRP4
secreted frizzled-related protein 4
chr4_-_111563278 0.611 NM_001204397
NM_001204398
NM_001204399
NM_153426
NM_153427
PITX2




paired-like homeodomain 2




chr3_-_165555167 0.594 BCHE
butyrylcholinesterase
chr7_+_93551015 0.587 NM_004126
GNG11
guanine nucleotide binding protein (G protein), gamma 11
chrX_-_137821514 0.585 NM_033642
FGF13
fibroblast growth factor 13
chr7_-_76829109 0.580 NM_006682
FGL2
fibrinogen-like 2
chr1_+_51434375 0.570 CDKN2C
cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
chr21_+_47545896 0.569 COL6A2
collagen, type VI, alpha 2
chr7_+_120629444 0.559 NM_001105533
C7orf58
chromosome 7 open reading frame 58
chr5_-_121412805 0.548 NM_001178102
LOX
lysyl oxidase
chrX_-_135863033 0.544 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr15_-_37391893 0.543 MEIS2
Meis homeobox 2
chr7_+_120628722 0.542 NM_024913
C7orf58
chromosome 7 open reading frame 58
chr14_+_96722546 0.539 NM_000710
BDKRB1
bradykinin receptor B1
chr4_+_77953942 0.533 SEPT11
septin 11
chr17_-_66951381 0.526 NM_007168
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chrX_+_135251454 0.525 NM_001159704
FHL1
four and a half LIM domains 1
chr2_+_223916861 0.523 NM_080671
KCNE4
potassium voltage-gated channel, Isk-related family, member 4
chr17_-_10421858 0.522 NM_005963
MYH1
myosin, heavy chain 1, skeletal muscle, adult
chr1_-_173176314 0.520 NM_003326
TNFSF4
tumor necrosis factor (ligand) superfamily, member 4
chr10_-_69752385 0.518 HERC4
hect domain and RLD 4
chr4_+_169418167 0.506 NM_001166108
NM_016081
PALLD

palladin, cytoskeletal associated protein

chr7_+_22767101 0.505 IL6
interleukin 6 (interferon, beta 2)
chr5_-_121414011 0.504 NM_002317
LOX
lysyl oxidase
chr2_-_87248942 0.504 NM_002665
NM_001032392
PLGLB2
PLGLB1
plasminogen-like B2
plasminogen-like B1
chr3_+_69812961 0.503 NM_006722
MITF
microphthalmia-associated transcription factor
chr18_-_53303129 0.502 NM_001243226
TCF4
transcription factor 4
chr14_+_103592663 0.501 NM_006291
TNFAIP2
tumor necrosis factor, alpha-induced protein 2
chr10_+_70847857 0.498 SRGN
serglycin
chr9_-_88714460 0.495 GOLM1
golgi membrane protein 1
chr8_+_22437983 0.495 NM_176871
NM_198042
PDLIM2

PDZ and LIM domain 2 (mystique)

chr12_+_6898605 0.493 NM_000616
NM_001195014
NM_001195015
NM_001195016
NM_001195017
CD4




CD4 molecule




chr1_-_201342318 0.490 TNNT2
troponin T type 2 (cardiac)
chr10_+_124320180 0.489 NM_004406
NM_007329
NM_017579
DMBT1


deleted in malignant brain tumors 1


chr3_-_99833348 0.489 NM_001042459
NM_182909
FILIP1L

filamin A interacting protein 1-like

chr1_+_174844655 0.487 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chr6_-_131291480 0.483 NM_001199389
EPB41L2
erythrocyte membrane protein band 4.1-like 2
chr18_+_32073343 0.479 DTNA
dystrobrevin, alpha
chr8_-_49833823 0.475 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chr17_-_46682333 0.475 NM_018952
HOXB6
homeobox B6
chrX_+_12994286 0.474 TMSB4X
thymosin beta 4, X-linked
chr17_-_63822660 0.472 NM_001037325
CEP112
centrosomal protein 112kDa
chr5_+_43609261 0.470 NNT
nicotinamide nucleotide transhydrogenase
chr1_-_86043932 0.464 NM_001134445
DDAH1
dimethylarginine dimethylaminohydrolase 1
chr7_-_83824216 0.463 NM_006080
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr15_-_90349819 0.459 ANPEP
alanyl (membrane) aminopeptidase
chr5_-_149535309 0.455 PDGFRB
platelet-derived growth factor receptor, beta polypeptide
chr21_+_40823779 0.450 NM_007341
SH3BGR
SH3 domain binding glutamic acid-rich protein
chr12_-_25101993 0.444 BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr1_-_110933683 0.442 NM_001201546
NM_001201547
NM_001201548
NM_001201549
NM_004696
SLC16A4




solute carrier family 16, member 4 (monocarboxylic acid transporter 5)




chr18_+_66465316 0.441 NM_024781
CCDC102B
coiled-coil domain containing 102B
chr4_-_120549827 0.441 NM_001083
PDE5A
phosphodiesterase 5A, cGMP-specific
chrX_-_135863104 0.440 ARHGEF6
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr15_+_68908878 0.435 NM_001190456
CORO2B
coronin, actin binding protein, 2B
chr7_+_73442486 0.435 ELN
elastin
chr12_-_25101923 0.435 BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr2_+_228192227 0.432 NM_020194
MFF
mitochondrial fission factor
chr2_-_44587812 0.430 NM_006036
PREPL
prolyl endopeptidase-like
chr12_+_13349601 0.429 NM_001423
EMP1
epithelial membrane protein 1
chr12_+_10365415 0.422 NM_031412
GABARAPL1
GABA(A) receptor-associated protein like 1
chr17_+_40834571 0.420 NM_003632
CNTNAP1
contactin associated protein 1
chr11_+_17332454 0.416


chr22_-_30642683 0.416 NM_002309
LIF
leukemia inhibitory factor (cholinergic differentiation factor)
chr3_-_165555252 0.415 NM_000055
BCHE
butyrylcholinesterase
chr12_-_9268513 0.415 A2M
alpha-2-macroglobulin
chr2_-_44586854 0.413 NM_001042385
NM_001042386
PREPL

prolyl endopeptidase-like

chrX_+_135278912 0.413 NM_001159701
NM_001159699
FHL1

four and a half LIM domains 1

chr5_+_140864626 0.411 NM_018928
NM_032406
PCDHGC4

protocadherin gamma subfamily C, 4

chr12_-_105322056 0.409 NM_032148
SLC41A2
solute carrier family 41, member 2
chr16_+_6069094 0.408 NM_001142333
NM_018723
RBFOX1

RNA binding protein, fox-1 homolog (C. elegans) 1

chr17_+_78518742 0.404 RPTOR
regulatory associated protein of MTOR, complex 1
chr12_-_9268522 0.401 NM_000014
A2M
alpha-2-macroglobulin
chr17_-_29648631 0.400 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr1_-_201390845 0.399 NM_003281
TNNI1
troponin I type 1 (skeletal, slow)
chr19_-_43690558 0.397 NM_001130014
NM_002781
PSG5

pregnancy specific beta-1-glycoprotein 5

chr17_+_39969205 0.395 FKBP10
FK506 binding protein 10, 65 kDa
chr13_-_114526166 0.395 GAS6
growth arrest-specific 6
chr19_+_11649578 0.395 NM_001299
CNN1
calponin 1, basic, smooth muscle
chr13_-_110802708 0.393 COL4A1
collagen, type IV, alpha 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.50 3.52e-08 GO:0048731 system development
17.66 7.05e-08 GO:0007517 muscle organ development
4.27 1.70e-07 GO:0048513 organ development
3.06 2.92e-07 GO:0007275 multicellular organismal development
3.15 4.08e-07 GO:0048856 anatomical structure development
2.43 1.68e-06 GO:0032501 multicellular organismal process
12.47 2.13e-06 GO:0061061 muscle structure development
2.78 3.04e-06 GO:0032502 developmental process
5.61 1.06e-04 GO:0009888 tissue development
20.08 2.22e-04 GO:0030198 extracellular matrix organization
47.93 6.21e-04 GO:0030199 collagen fibril organization
8.83 1.25e-03 GO:0001501 skeletal system development
3.69 2.15e-03 GO:0009653 anatomical structure morphogenesis
13.09 2.75e-03 GO:0043062 extracellular structure organization
3.49 9.42e-03 GO:0007399 nervous system development
3.00 1.34e-02 GO:0030154 cell differentiation
45.41 1.80e-02 GO:0030325 adrenal gland development
2.92 1.88e-02 GO:0048869 cellular developmental process
12.41 2.31e-02 GO:0060537 muscle tissue development
6.96 2.65e-02 GO:0043009 chordate embryonic development
6.87 2.89e-02 GO:0009792 embryo development ending in birth or egg hatching
11.61 3.18e-02 GO:0001655 urogenital system development

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
52.29 7.44e-08 GO:0005581 collagen
104.55 2.48e-06 GO:0005583 fibrillar collagen
3.65 2.14e-05 GO:0005576 extracellular region
4.83 2.51e-05 GO:0044421 extracellular region part
17.62 6.00e-05 GO:0044420 extracellular matrix part
5.21 9.55e-05 GO:0005615 extracellular space
8.24 1.12e-03 GO:0005578 proteinaceous extracellular matrix
191.66 2.20e-03 GO:0005589 collagen type VI
6.82 3.76e-03 GO:0031012 extracellular matrix
63.90 2.60e-02 GO:0030934 anchoring collagen

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
78.42 5.70e-04 GO:0048407 platelet-derived growth factor binding
14.25 2.17e-03 GO:0019838 growth factor binding
191.66 3.23e-03 GO:0005017 platelet-derived growth factor receptor activity
16.93 7.80e-03 GO:0005201 extracellular matrix structural constituent
95.84 1.60e-02 GO:0005021 vascular endothelial growth factor receptor activity
24.66 2.13e-02 GO:0005518 collagen binding