• All motifs sorted by activity significance
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• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: AGGUAGU

Z-value: 1.457

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_+_94023872	2.210	NM_000089	COL1A2	collagen, type I, alpha 2
chr2_+_189839078	1.755	NM_000090	COL3A1	collagen, type III, alpha 1
chr12_-_25102281	1.753	NM_001178091 NM_001178092 NM_005504	BCAT1	branched chain amino-acid transaminase 1, cytosolic
chr12_-_25055966	1.751	NM_001178093	BCAT1	branched chain amino-acid transaminase 1, cytosolic
chr1_-_92351613	1.709	NM_001195683 NM_003243	TGFBR3	transforming growth factor, beta receptor III
chr12_-_25055228	1.689	NM_001178094	BCAT1	branched chain amino-acid transaminase 1, cytosolic
chr1_-_92371558	1.537	NM_001195684	TGFBR3	transforming growth factor, beta receptor III
chr17_-_46688362	1.475	NM_004502	HOXB7	homeobox B7
chr9_-_16870719	1.197	NM_017637	BNC2	basonuclin 2
chr17_-_46682333	1.112	NM_018952	HOXB6	homeobox B6
chr20_+_37434294	0.902	NM_001172735 NM_015568	PPP1R16B	protein phosphatase 1, regulatory subunit 16B
chr1_+_164528586	0.872	NM_001204961 NM_001204963 NM_002585	PBX1	pre-B-cell leukemia homeobox 1
chr17_+_68165660	0.864	NM_000891	KCNJ2	potassium inwardly-rectifying channel, subfamily J, member 2
chr17_-_48278987	0.816	NM_000088	COL1A1	collagen, type I, alpha 1
chr10_+_11059854	0.785	NM_006561	CELF2	CUGBP, Elav-like family member 2
chr12_+_12869818	0.749	NM_004064	CDKN1B	cyclin-dependent kinase inhibitor 1B (p27, Kip1)
chr10_+_11047253	0.726	NM_001025077	CELF2	CUGBP, Elav-like family member 2
chr16_-_89043215	0.686	NM_005187	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr15_+_67000929	0.676	NM_001142861	SMAD6	SMAD family member 6
chr9_+_133710746	0.666	NM_005157	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase
chr7_-_45960738	0.646	NM_000598 NM_001013398	IGFBP3	insulin-like growth factor binding protein 3
chr9_+_133589267	0.586	NM_007313	ABL1	c-abl oncogene 1, non-receptor tyrosine kinase
chr12_-_69326946	0.578	NM_001005502 NM_198320	CPM	carboxypeptidase M
chr1_+_179923870	0.556	NM_014810	CEP350	centrosomal protein 350kDa
chr16_-_89007605	0.547	NM_175931	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr16_+_447175	0.540	NM_005009	NME4	non-metastatic cells 4, protein expressed in
chr7_-_23509972	0.515	NM_006547	IGF2BP3	insulin-like growth factor 2 mRNA binding protein 3
chr18_+_19749403	0.511	NM_005257	GATA6	GATA binding protein 6
chr12_-_69357019	0.500	NM_001874	CPM	carboxypeptidase M
chr10_+_11206928	0.491	NM_001025076 NM_001083591	CELF2	CUGBP, Elav-like family member 2
chr2_+_170590241	0.485	NM_144711	KLHL23	kelch-like 23 (Drosophila)
chr2_-_175547471	0.465	NM_001077269	WIPF1	WAS/WASL interacting protein family, member 1
chr12_-_58240746	0.461	NM_005730	CTDSP2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr1_-_207224298	0.459	NM_018566	YOD1	YOD1 OTU deubiquinating enzyme 1 homolog (S. cerevisiae)
chr2_-_99347588	0.452	NM_012214	MGAT4A	mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr1_+_193091057	0.449	NM_024529	CDC73	cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr17_+_28705922	0.449	NM_001304	CPD	carboxypeptidase D
chr14_+_72398816	0.449	NM_001204423	RGS6	regulator of G-protein signaling 6
chr5_-_55290601	0.433	NM_001190981 NM_002184 NM_175767	IL6ST	interleukin 6 signal transducer (gp130, oncostatin M receptor)
chr17_+_28707495	0.430	NM_001199775	CPD	carboxypeptidase D
chr9_-_79520878	0.428	NM_015225	PRUNE2	prune homolog 2 (Drosophila)
chr10_+_97803064	0.418	NM_001134375 NM_001134376 NM_019084	CCNJ	cyclin J
chr2_-_175499275	0.406	NM_003387	WIPF1	WAS/WASL interacting protein family, member 1
chr21_-_40033617	0.404	NM_001243432 NM_001136154 NM_004449	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr7_+_150068252	0.400	NM_014374	REPIN1	replication initiator 1
chr17_+_8214139	0.391	NM_025014	ARHGEF15	Rho guanine nucleotide exchange factor (GEF) 15
chr7_+_150065859	0.383	NM_001099695 NM_001099696 NM_013400	REPIN1	replication initiator 1
chr14_-_88460008	0.373	NM_001201402	GALC	galactosylceramidase
chr21_-_39870303	0.366	NM_001136155 NM_182918	ERG	v-ets erythroblastosis virus E26 oncogene homolog (avian)
chr2_+_172378856	0.352	NM_001127383 NM_024843	CYBRD1	cytochrome b reductase 1
chr10_+_181410	0.340	NM_001202464	ZMYND11	zinc finger, MYND-type containing 11
chr2_+_5832778	0.336	NM_003108	SOX11	SRY (sex determining region Y)-box 11
chr20_+_306205	0.287	NM_006943	SOX12	SRY (sex determining region Y)-box 12
chr14_+_72399149	0.280	NM_001204424	RGS6	regulator of G-protein signaling 6
chr3_-_47823386	0.272	NM_003074	SMARCC1	SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr20_+_49348050	0.268	NM_032521	PARD6B	par-6 partitioning defective 6 homolog beta (C. elegans)
chrX_-_129244471	0.256	NM_001421	ELF4	E74-like factor 4 (ets domain transcription factor)
chr13_-_33760215	0.254	NM_001243466 NM_178007	STARD13	StAR-related lipid transfer (START) domain containing 13
chr12_-_76478737	0.254	NM_004537 NM_139207	NAP1L1	nucleosome assembly protein 1-like 1
chr2_-_39664129	0.253	NM_003618	MAP4K3	mitogen-activated protein kinase kinase kinase kinase 3
chr16_+_69220940	0.252	NM_006750	SNTB2	syntrophin, beta 2 (dystrophin-associated protein A1, 59kDa, basic component 2)
chr21_-_46221662	0.251	NM_001202489 NM_003343 NM_182688	UBE2G2	ubiquitin-conjugating enzyme E2G 2
chr15_-_38856830	0.251	NM_001128602 NM_005739	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr6_+_32146161	0.242	NM_006913	RNF5	ring finger protein 5
chrX_-_77150907	0.238	NM_032121	MAGT1	magnesium transporter 1
chr3_-_178789597	0.230	NM_022470 NM_152240	ZMAT3	zinc finger, matrin-type 3
chr15_+_66994669	0.229	NM_005585	SMAD6	SMAD family member 6
chr14_-_88459469	0.228	NM_000153 NM_001201401	GALC	galactosylceramidase
chr13_-_33780142	0.227	NM_001243474 NM_052851	STARD13	StAR-related lipid transfer (START) domain containing 13
chrX_-_134156488	0.227	NM_001078173	FAM127C	family with sequence similarity 127, member C
chr13_-_33859835	0.219	NM_178006	STARD13	StAR-related lipid transfer (START) domain containing 13
chr21_+_30671217	0.214	NM_001186	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr2_-_160654736	0.212	NM_001198763 NM_001198764 NM_014880	CD302	CD302 molecule
chr1_+_153232178	0.207	NM_000427	LOR	loricrin
chr1_-_179112178	0.200	NM_001136000 NM_001168239 NM_005158	ABL2	v-abl Abelson murine leukemia viral oncogene homolog 2
chr12_+_62654120	0.194	NM_001252078 NM_001252079 NM_006313	USP15	ubiquitin specific peptidase 15
chr13_+_97874540	0.192	NM_144778 NM_207304	MBNL2	muscleblind-like 2 (Drosophila)
chr7_-_22396511	0.189	NM_012294	RAPGEF5	Rap guanine nucleotide exchange factor (GEF) 5
chr3_-_53381533	0.188	NM_018403	DCP1A	DCP1 decapping enzyme homolog A (S. cerevisiae)
chr10_+_180404	0.186	NM_006624 NM_001202465 NM_001202466 NM_212479	ZMYND11	zinc finger, MYND-type containing 11
chr3_-_36986535	0.174	NM_014831	TRANK1	tetratricopeptide repeat and ankyrin repeat containing 1
chr1_-_115259433	0.162	NM_002524	NRAS	neuroblastoma RAS viral (v-ras) oncogene homolog
chr9_-_135819995	0.162	NM_000368 NM_001162426 NM_001162427	TSC1	tuberous sclerosis 1
chr4_+_174089889	0.160	NM_017423	GALNT7	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 7 (GalNAc-T7)
chr9_+_110045516	0.155	NM_002874	RAD23B	RAD23 homolog B (S. cerevisiae)
chr21_-_28339405	0.152	NM_007038	ADAMTS5	ADAM metallopeptidase with thrombospondin type 1 motif, 5
chr13_-_41240607	0.149	NM_002015	FOXO1	forkhead box O1
chr16_+_81348564	0.147	NM_022041	GAN	gigaxonin
chr2_-_145090038	0.146	NM_001164629	GTDC1	glycosyltransferase-like domain containing 1
chrX_+_2746810	0.144	NM_001079855 NM_001184702 NM_001184703 NM_001184704 NM_003918	GYG2	glycogenin 2
chr22_+_50781717	0.141	NM_001242898 NM_001242899 NM_001242900 NM_014678	PPP6R2	protein phosphatase 6, regulatory subunit 2
chrX_-_129244652	0.139	NM_001127197	ELF4	E74-like factor 4 (ets domain transcription factor)
chr2_+_109335906	0.139	NM_006267	RANBP2	RAN binding protein 2
chr18_+_6834431	0.133	NM_001010000	ARHGAP28	Rho GTPase activating protein 28
chr1_-_51984994	0.133	NM_001981	EPS15	epidermal growth factor receptor pathway substrate 15
chr16_+_31484497	0.130	NM_015927	TGFB1I1	transforming growth factor beta 1 induced transcript 1
chr6_+_34206567	0.129	NM_145905	HMGA1	high mobility group AT-hook 1
chr2_-_145052059	0.127	NM_001006636	GTDC1	glycosyltransferase-like domain containing 1
chr14_-_57735614	0.124	NM_006544	EXOC5	exocyst complex component 5
chr3_+_61547179	0.120	NM_002841	PTPRG	protein tyrosine phosphatase, receptor type, G
chr8_+_22102618	0.120	NM_001722	POLR3D	polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
chr8_+_58906968	0.120	NM_147189	FAM110B	family with sequence similarity 110, member B
chr21_+_17102370	0.116	NM_013396	USP25	ubiquitin specific peptidase 25
chr20_-_45035253	0.115	NM_133171 NM_182764	ELMO2	engulfment and cell motility 2
chr3_-_37034609	0.114	NM_014805	EPM2AIP1	EPM2A (laforin) interacting protein 1
chr10_-_94050799	0.112	NM_014912	CPEB3	cytoplasmic polyadenylation element binding protein 3
chr8_+_121137297	0.110	NM_021110	COL14A1	collagen, type XIV, alpha 1
chr1_+_91966653	0.109	NM_001134420	CDC7	cell division cycle 7 homolog (S. cerevisiae)
chr8_+_37594078	0.108	NM_001003791 NM_007175	ERLIN2	ER lipid raft associated 2
chr17_-_7145742	0.107	NM_007278	GABARAP	GABA(A) receptor-associated protein
chr7_-_27205148	0.107	NM_152739	HOXA9	homeobox A9
chr1_+_99729847	0.105	NM_001166252 NM_014839	LPPR4	lipid phosphate phosphatase-related protein type 4
chr17_+_8213555	0.105	NM_173728	ARHGEF15	Rho guanine nucleotide exchange factor (GEF) 15
chr11_+_111944967	0.102	NM_001082969 NM_001082970 NM_018195	C11orf57	chromosome 11 open reading frame 57
chr9_+_123850573	0.101	NM_007018	CNTRL	centriolin
chr1_+_91966365	0.100	NM_001134419 NM_003503	CDC7	cell division cycle 7 homolog (S. cerevisiae)
chr1_-_205601999	0.100	NM_001973 NM_021795	ELK4	ELK4, ETS-domain protein (SRF accessory protein 1)
chr7_+_99156020	0.098	NM_001083956 NM_001085366 NM_024061 NM_138494	ZNF655	zinc finger protein 655
chr3_-_150264280	0.097	NM_014445	SERP1	stress-associated endoplasmic reticulum protein 1
chr2_-_144994905	0.096	NM_024659	GTDC1	glycosyltransferase-like domain containing 1
chr7_+_99156427	0.096	NM_001009958 NM_001009960 NM_001085367 NM_001085368	ZNF655	zinc finger protein 655
chr2_-_142889269	0.095	NM_018557	LRP1B	low density lipoprotein receptor-related protein 1B
chr9_+_115983807	0.093	NM_001859	SLC31A1	solute carrier family 31 (copper transporters), member 1
chr15_+_79724857	0.093	NM_015206	KIAA1024	KIAA1024
chr3_+_50712671	0.093	NM_004947	DOCK3	dedicator of cytokinesis 3
chr10_-_38146221	0.092	NM_021045	ZNF248	zinc finger protein 248
chr16_-_30022300	0.092	NM_003586	DOC2A	double C2-like domains, alpha
chr16_+_31483066	0.090	NM_001042454 NM_001164719	TGFB1I1	transforming growth factor beta 1 induced transcript 1
chr16_+_70333058	0.087	NM_001014449 NM_001014451 NM_007242	DDX19B	DEAD (Asp-Glu-Ala-As) box polypeptide 19B
chr7_-_83824216	0.086	NM_006080	SEMA3A	sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr1_-_103574051	0.085	NM_001190709 NM_001854 NM_080629 NM_080630	COL11A1	collagen, type XI, alpha 1
chr6_+_34204576	0.085	NM_002131 NM_145899 NM_145903	HMGA1	high mobility group AT-hook 1
chr1_+_113615787	0.084	NM_014813	LRIG2	leucine-rich repeats and immunoglobulin-like domains 2
chr16_+_70380763	0.084	NM_018332	DDX19A	DEAD (Asp-Glu-Ala-As) box polypeptide 19A
chr6_+_170102236	0.083	NM_001029863	C6orf120	chromosome 6 open reading frame 120
chr17_-_40540491	0.081	NM_003150 NM_139276	STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)
chr17_-_9929567	0.079	NM_001130831	GAS7	growth arrest-specific 7
chr4_+_106473776	0.078	NM_001242729 NM_017700	ARHGEF38	Rho guanine nucleotide exchange factor (GEF) 38
chrX_+_134166318	0.077	NM_001078171	FAM127A	family with sequence similarity 127, member A
chr17_-_40540359	0.075	NM_213662	STAT3	signal transducer and activator of transcription 3 (acute-phase response factor)
chr11_-_798196	0.070	NM_001191061	SLC25A22	solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr16_-_22385596	0.067	NM_001802	CDR2	cerebellar degeneration-related protein 2, 62kDa
chr12_-_93323088	0.065	NM_003566	EEA1	early endosome antigen 1
chr14_+_72399785	0.064	NM_001204416 NM_001204417 NM_001204418 NM_001204419 NM_001204420 NM_001204421 NM_001204422 NM_004296	RGS6	regulator of G-protein signaling 6
chr20_+_44509847	0.061	NM_080603	ZSWIM1	zinc finger, SWIM-type containing 1
chr3_-_176915012	0.058	NM_024665	TBL1XR1	transducin (beta)-like 1 X-linked receptor 1
chr6_-_24911194	0.058	NM_014722	FAM65B	family with sequence similarity 65, member B
chr12_+_50794591	0.056	NM_001170803 NM_001170804 NM_001170808 NM_052879 NM_199188 NM_199190	LARP4	La ribonucleoprotein domain family, member 4
chr6_-_35464716	0.053	NM_003214	TEAD3	TEA domain family member 3
chr11_+_10772781	0.051	NM_014633	CTR9	Ctr9, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
chr12_-_102872329	0.049	NM_001111284	IGF1	insulin-like growth factor 1 (somatomedin C)
chr16_-_3285069	0.049	NM_001145447 NM_003454	ZNF200	zinc finger protein 200
chr1_-_200379165	0.045	NM_012482	ZNF281	zinc finger protein 281
chr6_+_134274247	0.045	NM_004865	TBPL1	TBP-like 1
chr5_+_56110899	0.043	NM_005921	MAP3K1	mitogen-activated protein kinase kinase kinase 1
chr8_+_59465727	0.042	NM_001007067 NM_001007068 NM_001007069 NM_001007070 NM_005625	SDCBP	syndecan binding protein (syntenin)
chr11_-_77899640	0.042	NM_001029859	KCTD21	potassium channel tetramerisation domain containing 21
chr9_-_111882209	0.041	NM_032012	C9orf5	chromosome 9 open reading frame 5
chr22_-_22221953	0.040	NM_002745 NM_138957	MAPK1	mitogen-activated protein kinase 1
chr10_+_102672325	0.039	NM_001136123 NM_001243770 NM_018121	FAM178A	family with sequence similarity 178, member A
chr7_-_11871735	0.036	NM_015204	THSD7A	thrombospondin, type I, domain containing 7A
chrX_+_67718623	0.035	NM_001195214 NM_173834	YIPF6	Yip1 domain family, member 6
chr22_+_30279064	0.034	NM_021090 NM_153050 NM_153051	MTMR3	myotubularin related protein 3
chr7_-_138665853	0.034	NM_001164665 NM_020910	KIAA1549	KIAA1549
chr13_-_102568994	0.034	NM_004115	FGF14	fibroblast growth factor 14
chr6_-_7313352	0.031	NM_003144	SSR1	signal sequence receptor, alpha
chr8_+_1449531	0.031	NM_004745	DLGAP2	discs, large (Drosophila) homolog-associated protein 2
chr15_-_40600118	0.030	NM_004573	PLCB2	phospholipase C, beta 2
chr17_-_45266664	0.029	NM_001114091 NM_001256	CDC27	cell division cycle 27 homolog (S. cerevisiae)
chr1_+_101003692	0.026	NM_022049	GPR88	G protein-coupled receptor 88
chr17_-_9940004	0.024	NM_201432	GAS7	growth arrest-specific 7
chr11_+_63871240	0.023	NM_013280	FLRT1	fibronectin leucine rich transmembrane protein 1
chr22_+_39853316	0.021	NM_002409	MGAT3	mannosyl (beta-1,4-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase
chr17_+_53342320	0.021	NM_002126	HLF	hepatic leukemia factor
chr8_-_17580024	0.020	NM_001166393	MTUS1	microtubule associated tumor suppressor 1
chr6_+_32605182	0.019	NM_002122	HLA-DQA1	major histocompatibility complex, class II, DQ alpha 1
chr6_+_133562488	0.019	NM_004100 NM_172103 NM_172105	EYA4	eyes absent homolog 4 (Drosophila)
chrX_-_124097601	0.019	NM_001163278 NM_001163279 NM_014253	ODZ1	odz, odd Oz/ten-m homolog 1 (Drosophila)
chr1_+_18957499	0.019	NM_001135254 NM_002584 NM_013945	PAX7	paired box 7
chr8_-_17658385	0.019	NM_001001924 NM_001001925	MTUS1	microtubule associated tumor suppressor 1
chr4_+_56212381	0.016	NM_024592	SRD5A3	steroid 5 alpha-reductase 3
chr1_+_215256559	0.015	NM_001017425 NM_014217	KCNK2	potassium channel, subfamily K, member 2
chr18_-_24445652	0.011	NM_001650	AQP4	aquaporin 4
chr6_+_34204647	0.011	NM_145901 NM_145902	HMGA1	high mobility group AT-hook 1
chr12_+_12764755	0.010	NM_001310	CREBL2	cAMP responsive element binding protein-like 2
chr6_-_84419108	0.010	NM_001242793 NM_001242794 NM_014841	SNAP91	synaptosomal-associated protein, 91kDa homolog (mouse)
chr21_+_30671736	0.009	NM_206866	BACH1	BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr8_-_17579729	0.008	NM_001001931	MTUS1	microtubule associated tumor suppressor 1
chr3_+_101498028	0.008	NM_145037	FAM55C	family with sequence similarity 55, member C
chr17_-_60142598	0.008	NM_005121	MED13	mediator complex subunit 13
chr8_-_82754427	0.007	NM_022133 NM_152836 NM_152837	SNX16	sorting nexin 16
chr1_+_26737232	0.006	NM_024674	LIN28A	lin-28 homolog A (C. elegans)
chr2_-_48982809	0.004	NM_000233	LHCGR	luteinizing hormone/choriogonadotropin receptor
chr14_-_92572950	0.004	NM_001127696 NM_001127697 NM_001164774 NM_001164776 NM_001164777 NM_001164778 NM_001164779 NM_001164780 NM_001164781 NM_001164782 NM_004993 NM_030660	ATXN3	ataxin 3
chr1_+_36023389	0.004	NM_001014839 NM_001014841 NM_014284	NCDN	neurochondrin
chr12_-_102874373	0.003	NM_000618 NM_001111283 NM_001111285	IGF1	insulin-like growth factor 1 (somatomedin C)
chr4_-_47840058	0.003	NM_006587	CORIN	corin, serine peptidase
chr6_-_13814546	0.003	NM_001031713	CCDC90A	coiled-coil domain containing 90A
chr11_-_797955	0.003	NM_001191060	SLC25A22	solute carrier family 25 (mitochondrial carrier: glutamate), member 22
chr4_-_52904424	0.001	NM_000232	SGCB	sarcoglycan, beta (43kDa dystrophin-associated glycoprotein)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
49.02	2.02e-03	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
13.49	8.41e-03	GO:0009887	organ morphogenesis
137.60	8.86e-03	GO:0043588	skin development
131.88	9.66e-03	GO:0030199	collagen fibril organization
6.85	1.69e-02	GO:0009653	anatomical structure morphogenesis
77.25	2.86e-02	GO:0034101	erythrocyte homeostasis
67.40	3.76e-02	GO:0048704	embryonic skeletal system morphogenesis

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
287.58	3.07e-04	GO:0005583	fibrillar collagen
95.94	2.93e-03	GO:0005581	collagen
32.39	2.59e-02	GO:0044420	extracellular matrix part

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
287.58	2.49e-04	GO:0048407	platelet-derived growth factor binding
47.09	2.94e-04	GO:0019838	growth factor binding
75.41	3.86e-03	GO:0046332	SMAD binding
46.62	1.01e-02	GO:0005201	extracellular matrix structural constituent