• All motifs sorted by activity significance
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• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: FOXP3.p2

Z-value: 1.121

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr6_-_32497925	2.331	NM_002125	HLA-DRB5	major histocompatibility complex, class II, DR beta 5
chr17_-_29641087	2.263		EVI2B	ecotropic viral integration site 2B
chr17_-_29641094	2.232	NM_006495	EVI2B	ecotropic viral integration site 2B
chr17_-_29641068	2.191		EVI2B	ecotropic viral integration site 2B
chr2_-_158300517	1.871	NM_004288	CYTIP	cytohesin 1 interacting protein
chr6_-_32557431	1.752	NM_001243965 NM_002124	HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chrX_-_100641143	1.746	NM_000061	BTK	Bruton agammaglobulinemia tyrosine kinase
chr7_-_150329285	1.504		GIMAP6	GTPase, IMAP family member 6
chr4_+_40198526	1.406	NM_004310	RHOH	ras homolog gene family, member H
chr6_-_154677868	1.238	NM_001130700 NM_015553	IPCEF1	interaction protein for cytohesin exchange factors 1
chr7_-_150329735	1.217	NM_001244071 NM_001244072 NM_024711	GIMAP6	GTPase, IMAP family member 6
chr2_-_21225640	1.177		APOB	apolipoprotein B (including Ag(x) antigen)
chr22_+_21128378	1.159	NM_000185	SERPIND1	serpin peptidase inhibitor, clade D (heparin cofactor), member 1
chr10_+_114135013	1.114	NM_203380	ACSL5	acyl-CoA synthetase long-chain family member 5
chr1_+_15990300	1.065
chr1_+_207627614	1.022	NM_001006658 NM_001877	CR2	complement component (3d/Epstein Barr virus) receptor 2
chr7_+_26400503	0.905	NM_001199837	SNX10	sorting nexin 10
chr16_+_72088507	0.845	NM_001126102 NM_005143	HP	haptoglobin
chr11_+_116700620	0.829	NM_000040	APOC3	apolipoprotein C-III
chr15_-_93277303	0.823		FAM174B	family with sequence similarity 174, member B
chr4_+_88896801	0.797	NM_000582 NM_001040058 NM_001040060 NM_001251829 NM_001251830	SPP1	secreted phosphoprotein 1
chr4_+_15779887	0.774	NM_001775	CD38	CD38 molecule
chr9_-_116840545	0.721		AMBP	alpha-1-microglobulin/bikunin precursor
chr1_+_174844655	0.697	NM_001035230	RABGAP1L	RAB GTPase activating protein 1-like
chr6_+_64356430	0.686	NM_015153	PHF3	PHD finger protein 3
chr1_+_192544856	0.675	NM_002922	RGS1	regulator of G-protein signaling 1
chr1_-_207095198	0.662	NM_001193338 NM_001142473 NM_005449	FAIM3	Fas apoptotic inhibitory molecule 3
chr9_-_36375965	0.636		RNF38	ring finger protein 38
chr9_-_116840551	0.615		AMBP	alpha-1-microglobulin/bikunin precursor
chr9_-_116840460	0.604		AMBP	alpha-1-microglobulin/bikunin precursor
chr15_-_80263460	0.568	NM_001114735 NM_004049	BCL2A1	BCL2-related protein A1
chr1_-_150738232	0.533		CTSS	cathepsin S
chr1_-_150738292	0.529	NM_001199739 NM_004079	CTSS	cathepsin S
chr8_+_107738239	0.525	NM_001198534 NM_001198535	OXR1	oxidation resistance 1
chr11_+_124824012	0.500	NM_025004	CCDC15	coiled-coil domain containing 15
chr12_+_100897137	0.500	NM_001206992 NM_001206993	NR1H4	nuclear receptor subfamily 1, group H, member 4
chr9_-_116840604	0.479		AMBP	alpha-1-microglobulin/bikunin precursor
chr4_+_88896838	0.466		SPP1	secreted phosphoprotein 1
chr17_-_10421858	0.465	NM_005963	MYH1	myosin, heavy chain 1, skeletal muscle, adult
chr4_+_88896899	0.452		SPP1	secreted phosphoprotein 1
chr12_+_100867739	0.446		NR1H4	nuclear receptor subfamily 1, group H, member 4
chr6_+_87969619	0.421		ZNF292	zinc finger protein 292
chr16_+_15068832	0.413	NM_015027	PDXDC1	pyridoxal-dependent decarboxylase domain containing 1
chr4_-_186697065	0.388	NM_001145673	SORBS2	sorbin and SH3 domain containing 2
chr4_+_70146216	0.385	NM_001207004 NM_053039	UGT2B28	UDP glucuronosyltransferase 2 family, polypeptide B28
chr6_+_33043702	0.375	NM_002121	HLA-DPB1	major histocompatibility complex, class II, DP beta 1
chr19_+_42381189	0.347	NM_001783 NM_021601	CD79A	CD79a molecule, immunoglobulin-associated alpha
chr12_+_6554032	0.339	NM_001242	CD27	CD27 molecule
chr9_-_116840673	0.337	NM_001633	AMBP	alpha-1-microglobulin/bikunin precursor
chr2_+_143635194	0.336	NM_001032998 NM_001199241 NM_003937	KYNU	kynureninase
chr17_+_27369917	0.333	NM_016518	PIPOX	pipecolic acid oxidase
chr17_+_41052813	0.332	NM_000151	G6PC	glucose-6-phosphatase, catalytic subunit
chr11_+_124824076	0.327		CCDC15	coiled-coil domain containing 15
chr1_-_160549226	0.296		CD84	CD84 molecule
chr14_-_21899866	0.293	NM_001170629	CHD8	chromodomain helicase DNA binding protein 8
chr12_+_15475445	0.288		PTPRO	protein tyrosine phosphatase, receptor type, O
chr6_-_112041253	0.287	NM_153047	FYN	FYN oncogene related to SRC, FGR, YES
chrX_-_106960268	0.286	NM_004089	TSC22D3	TSC22 domain family, member 3
chr3_-_121264780	0.280	NM_199420	POLQ	polymerase (DNA directed), theta
chr6_-_11382501	0.279	NM_001142393	NEDD9	neural precursor cell expressed, developmentally down-regulated 9
chr12_+_100867550	0.266	NM_001206977 NM_001206978 NM_001206979 NM_005123	NR1H4	nuclear receptor subfamily 1, group H, member 4
chr1_-_173886464	0.263	NM_000488	SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1
chr17_+_67410825	0.263	NM_002758	MAP2K6	mitogen-activated protein kinase kinase 6
chr6_-_32634287	0.263	NM_001243961 NM_002123	HLA-DQB1	major histocompatibility complex, class II, DQ beta 1
chr6_-_76203256	0.245	NM_015687	FILIP1	filamin A interacting protein 1
chr16_+_72097124	0.243	NM_020995	HPR	haptoglobin-related protein
chrX_+_78200828	0.231	NM_014499 NM_198333	P2RY10	purinergic receptor P2Y, G-protein coupled, 10
chr2_-_89513056	0.230		IGKC	immunoglobulin kappa constant
chr1_+_116925991	0.228	NM_001160234	ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr13_-_99910548	0.226	NM_001098200 NM_005292	GPR18	G protein-coupled receptor 18
chr4_+_71062241	0.225	NM_017855	ODAM	odontogenic, ameloblast asssociated
chr14_-_35344852	0.225	NM_013448 NM_182648	BAZ1A	bromodomain adjacent to zinc finger domain, 1A
chrX_-_135863502	0.220	NM_004840	ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr4_-_186732047	0.220	NM_001145672	SORBS2	sorbin and SH3 domain containing 2
chr16_-_52581713	0.211	NM_001146188	TOX3	TOX high mobility group box family member 3
chr1_+_198608136	0.211	NM_002838 NM_080921 NM_080923	PTPRC	protein tyrosine phosphatase, receptor type, C
chr19_-_23578226	0.210	NM_003430	ZNF91	zinc finger protein 91
chr12_+_53497273	0.205	NM_003578	SOAT2	sterol O-acyltransferase 2
chr1_-_160832466	0.204	NM_001166663 NM_001166664 NM_016382	CD244	CD244 molecule, natural killer cell receptor 2B4
chr19_-_6720585	0.201	NM_000064	C3	complement component 3
chr6_+_144612872	0.198	NM_007124	UTRN	utrophin
chr2_-_89619820	0.195		IGKC	immunoglobulin kappa constant
chr10_-_91102430	0.195		LIPA	lipase A, lysosomal acid, cholesterol esterase
chr12_+_51318515	0.190	NM_014033	METTL7A	methyltransferase like 7A
chr8_+_92114846	0.189	NM_001129890	LRRC69	leucine rich repeat containing 69
chr5_-_59783885	0.189	NM_001165899	PDE4D	phosphodiesterase 4D, cAMP-specific
chr8_-_17752847	0.186	NM_147203 NM_201553 NM_004467 NM_201552	FGL1	fibrinogen-like 1
chr16_-_70099755	0.184		PDXDC2P	pyridoxal-dependent decarboxylase domain containing 2, pseudogene
chr5_-_94417185	0.183		MCTP1	multiple C2 domains, transmembrane 1
chr8_+_124194751	0.179	NM_032899 NM_207006	FAM83A	family with sequence similarity 83, member A
chr15_+_58724174	0.173	NM_000236	LIPC	lipase, hepatic
chr1_-_115269672	0.161		CSDE1	cold shock domain containing E1, RNA-binding
chr16_-_12897693	0.155	NM_001099455 NM_018340	CPPED1	calcineurin-like phosphoesterase domain containing 1
chr4_-_103245468	0.154	NM_001135148	SLC39A8	solute carrier family 39 (zinc transporter), member 8
chr2_+_170440846	0.153	NM_004792	PPIG	peptidylprolyl isomerase G (cyclophilin G)
chr19_-_55767103	0.152		PPP6R1	protein phosphatase 6, regulatory subunit 1
chr3_+_63884074	0.151	NM_001177387	ATXN7	ataxin 7
chr6_+_106546736	0.147	NM_182907	PRDM1	PR domain containing 1, with ZNF domain
chr6_+_31540092	0.147	NM_000595	LTA	lymphotoxin alpha (TNF superfamily, member 1)
chr5_+_67586466	0.146	NM_181504	PIK3R1	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr16_+_31724564	0.145		ZNF720	zinc finger protein 720
chr6_+_31730772	0.142	NM_001039651	C6orf26	chromosome 6 open reading frame 26
chr1_-_161147757	0.136	NM_001199873 NM_001199874 NM_003779	B4GALT3	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 3
chr16_+_2867163	0.136	NM_006799 NM_144956 NM_144957	PRSS21	protease, serine, 21 (testisin)
chr9_+_12693385	0.136	NM_000550	TYRP1	tyrosinase-related protein 1
chr6_-_131384387	0.136	NM_001135554 NM_001135555 NM_001199388 NM_001431	EPB41L2	erythrocyte membrane protein band 4.1-like 2
chr1_-_173886401	0.135		SERPINC1	serpin peptidase inhibitor, clade C (antithrombin), member 1
chr17_+_41006094	0.130		AOC3	amine oxidase, copper containing 3 (vascular adhesion protein 1)
chr16_+_2867227	0.129		PRSS21	protease, serine, 21 (testisin)
chr11_-_47545539	0.128	NM_001172639	CELF1	CUGBP, Elav-like family member 1
chr1_-_78444772	0.127	NM_003902	FUBP1	far upstream element (FUSE) binding protein 1
chr1_-_204459445	0.127	NM_002646	PIK3C2B	phosphoinositide-3-kinase, class 2, beta polypeptide
chr22_-_45608232	0.125		KIAA0930	KIAA0930
chr14_-_106829736	0.124		IGHA1 IGHD IGHG3 IGHM SKAP2	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu src kinase associated phosphoprotein 2
chr1_+_244216506	0.124	NM_006352	ZNF238	zinc finger protein 238
chr2_-_215896809	0.124	NM_015657	ABCA12	ATP-binding cassette, sub-family A (ABC1), member 12
chr2_+_103035148	0.123	NM_003853	IL18RAP	interleukin 18 receptor accessory protein
chr1_+_66797775	0.122	NM_001037339	PDE4B	phosphodiesterase 4B, cAMP-specific
chrX_-_30595883	0.121	NM_025159	CXorf21	chromosome X open reading frame 21
chr2_+_170366211	0.120	NM_006063	KBTBD10	kelch repeat and BTB (POZ) domain containing 10
chr17_+_6659356	0.114		XAF1	XIAP associated factor 1
chr8_+_17829848	0.112		PCM1	pericentriolar material 1
chr15_-_65412175	0.108		PDCD7	programmed cell death 7
chr2_-_74382352	0.106
chr1_+_212788359	0.105	NM_001206486	ATF3	activating transcription factor 3
chr13_+_96085852	0.103	NM_001160100 NM_182848	CLDN10	claudin 10
chr2_-_110962577	0.102	NM_000272 NM_001128178 NM_001128179 NM_207181	NPHP1	nephronophthisis 1 (juvenile)
chr8_-_37727937	0.102		RAB11FIP1	RAB11 family interacting protein 1 (class I)
chr12_+_53497287	0.101		SOAT2	sterol O-acyltransferase 2
chr1_-_89591685	0.101	NM_004120	GBP2	guanylate binding protein 2, interferon-inducible
chr19_-_36304200	0.099	NM_021232	PRODH2	proline dehydrogenase (oxidase) 2
chrX_-_135863033	0.099		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr13_+_111839172	0.099	NM_001113513	ARHGEF7	Rho guanine nucleotide exchange factor (GEF) 7
chr3_+_119316694	0.097	NM_001206960 NM_001206961 NM_015900	PLA1A	phospholipase A1 member A
chr6_-_25874439	0.097	NM_001098486 NM_006632	SLC17A3	solute carrier family 17 (sodium phosphate), member 3
chr19_+_34710327	0.097		LSM14A	LSM14A, SCD6 homolog A (S. cerevisiae)
chr19_+_21106058	0.095	NM_003429	ZNF85	zinc finger protein 85
chr10_+_118380451	0.094	NM_005396	PNLIPRP2	pancreatic lipase-related protein 2
chr3_-_178984789	0.093	NM_001163677 NM_171828	KCNMB3	potassium large conductance calcium-activated channel, subfamily M beta member 3
chr11_+_87032428	0.093		TMEM135	transmembrane protein 135
chr13_+_49684388	0.092	NM_014923	FNDC3A	fibronectin type III domain containing 3A
chr2_-_166930130	0.091	NM_001165963 NM_001165964 NM_006920	SCN1A	sodium channel, voltage-gated, type I, alpha subunit
chr5_+_157158322	0.091	NM_017872	THG1L	tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr10_-_45474210	0.090	NM_007021	C10orf10	chromosome 10 open reading frame 10
chr1_+_52195603	0.089		OSBPL9	oxysterol binding protein-like 9
chr4_+_124317884	0.088	NM_199327	SPRY1	sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr17_+_6659155	0.087	NM_017523 NM_199139	XAF1	XIAP associated factor 1
chr4_+_71226477	0.086	NM_012390	SMR3B SMR3A	submaxillary gland androgen regulated protein 3B submaxillary gland androgen regulated protein 3A
chr4_-_186732208	0.086	NM_001145671	SORBS2	sorbin and SH3 domain containing 2
chr18_-_74728963	0.084		MBP	myelin basic protein
chr19_+_52266640	0.083	NM_001462	FPR2	formyl peptide receptor 2
chr15_+_85666291	0.081		PDE8A	phosphodiesterase 8A
chr19_-_36303766	0.080		PRODH2	proline dehydrogenase (oxidase) 2
chr17_+_75181294	0.079	NM_001144001	SEC14L1	SEC14-like 1 (S. cerevisiae)
chr1_+_174933904	0.079	NM_001243764	RABGAP1L	RAB GTPase activating protein 1-like
chr15_+_48498497	0.077	NM_000338 NM_001184832	SLC12A1	solute carrier family 12 (sodium/potassium/chloride transporters), member 1
chr19_+_42724431	0.077	NM_133444	ZNF526	zinc finger protein 526
chr17_-_45899133	0.075	NM_145798	OSBPL7	oxysterol binding protein-like 7
chr8_-_90996785	0.074		NBN	nibrin
chr2_+_1418179	0.073	NM_175721 NM_175722	TPO	thyroid peroxidase
chr17_-_45899118	0.073		OSBPL7	oxysterol binding protein-like 7
chr1_-_78444690	0.073		FUBP1	far upstream element (FUSE) binding protein 1
chr3_-_170744767	0.073	NM_000340	SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2
chr14_+_102276279	0.072		PPP2R5C	protein phosphatase 2, regulatory subunit B', gamma
chr4_-_74088773	0.072		ANKRD17	ankyrin repeat domain 17
chr15_+_77287688	0.071		PSTPIP1	proline-serine-threonine phosphatase interacting protein 1
chr3_-_172241060	0.071	NM_001190943 NM_001190942 NM_003810	TNFSF10	tumor necrosis factor (ligand) superfamily, member 10
chr1_-_109935869	0.070	NM_001205228	SORT1	sortilin 1
chr2_+_166152282	0.070	NM_001040143	SCN2A	sodium channel, voltage-gated, type II, alpha subunit
chr2_-_110962539	0.069		NPHP1	nephronophthisis 1 (juvenile)
chr1_-_160549271	0.068	NM_001184879 NM_001184881 NM_001184882 NM_003874	CD84	CD84 molecule
chr11_+_30252562	0.067	NM_000510 NM_001018080	FSHB	follicle stimulating hormone, beta polypeptide
chr16_-_71748697	0.066	NM_015020	PHLPP2	PH domain and leucine rich repeat protein phosphatase 2
chr1_-_203144910	0.065	NM_004997	MYBPH	myosin binding protein H
chr18_+_77441429	0.065	NM_001202504	CTDP1	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1
chr16_+_70333058	0.064	NM_001014449 NM_001014451 NM_007242	DDX19B	DEAD (Asp-Glu-Ala-As) box polypeptide 19B
chr5_+_115898218	0.062
chr13_+_49280619	0.061	NM_020377	CYSLTR2	cysteinyl leukotriene receptor 2
chr3_-_9885659	0.059		RPUSD3	RNA pseudouridylate synthase domain containing 3
chr3_-_170744458	0.057		SLC2A2	solute carrier family 2 (facilitated glucose transporter), member 2
chr9_-_75567915	0.057		ALDH1A1	aldehyde dehydrogenase 1 family, member A1
chr4_-_100356290	0.056	NM_001166504	ADH7	alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr9_+_134305476	0.056	NM_013318	PRRC2B	proline-rich coiled-coil 2B
chr5_-_32388595	0.054		ZFR	zinc finger RNA binding protein
chr3_+_149192479	0.053		TM4SF4	transmembrane 4 L six family member 4
chr4_-_164534656	0.053	NM_017923	MARCH1	membrane-associated ring finger (C3HC4) 1
chr1_+_67632168	0.053	NM_144701	IL23R	interleukin 23 receptor
chr5_+_40909617	0.052		C7	complement component 7
chr5_+_43602738	0.052	NM_012343	NNT	nicotinamide nucleotide transhydrogenase
chr1_-_182922504	0.051	NM_030933	SHCBP1L	SHC SH2-domain binding protein 1-like
chr7_+_48211054	0.051	NM_152701	ABCA13	ATP-binding cassette, sub-family A (ABC1), member 13
chr9_-_99064385	0.050	NM_000197	HSD17B3	hydroxysteroid (17-beta) dehydrogenase 3
chr10_+_112344076	0.050		SMC3	structural maintenance of chromosomes 3
chrX_-_135863104	0.050		ARHGEF6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr19_-_40440532	0.049	NM_003890	FCGBP	Fc fragment of IgG binding protein
chr10_+_51576284	0.049	NM_001145262	NCOA4	nuclear receptor coactivator 4
chr2_-_145052059	0.048	NM_001006636	GTDC1	glycosyltransferase-like domain containing 1
chr17_+_72581056	0.048	NM_152460	C17orf77	chromosome 17 open reading frame 77
chr11_-_113345841	0.048	NM_000795 NM_016574	DRD2	dopamine receptor D2
chr15_+_77287738	0.048		PSTPIP1	proline-serine-threonine phosphatase interacting protein 1

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
139.07	3.49e-03	GO:0042613	MHC class II protein complex
3.01	1.18e-02	GO:0071944	cell periphery
10.51	1.45e-02	GO:0005768	endosome
64.94	1.65e-02	GO:0042611	MHC protein complex
14.25	3.95e-02	GO:0010008	endosome membrane
14.11	4.07e-02	GO:0044440	endosomal part
41.48	4.07e-02	GO:0031902	late endosome membrane

Nothing significant found in function category.