Motif ID: GFI1.p2

Z-value: 2.159


Transcription factors associated with GFI1.p2:

Gene SymbolEntrez IDGene Name
GFI1 2672 growth factor independent 1 transcription repressor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GFI1chr1_-_92951593-0.533.5e-02Click!


Activity profile for motif GFI1.p2.

activity profile for motif GFI1.p2


Sorted Z-values histogram for motif GFI1.p2

Sorted Z-values for motif GFI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_1619473 2.939 MIR22HG
MIR22 host gene (non-protein coding)
chr14_+_104182045 2.691 NM_001198953
NM_024071
ZFYVE21

zinc finger, FYVE domain containing 21

chr6_-_167040700 2.154 NM_021135
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr12_-_21810779 1.976 NM_002300
LDHB
lactate dehydrogenase B
chr12_-_21810754 1.963 LDHB
lactate dehydrogenase B
chr12_-_21810733 1.947 LDHB
lactate dehydrogenase B
chr12_-_21810720 1.934 NM_001174097
LDHB
lactate dehydrogenase B
chr12_-_28124915 1.891 NM_002820
NM_198965
PTHLH

parathyroid hormone-like hormone

chr10_+_17271276 1.881 VIM
vimentin
chr12_-_21810769 1.878 LDHB
lactate dehydrogenase B
chr10_+_17271277 1.852 VIM
vimentin
chr8_-_98290171 1.832 NM_033512
TSPYL5
TSPY-like 5
chr11_+_13299260 1.820 NM_001030272
NM_001030273
NM_001178
ARNTL


aryl hydrocarbon receptor nuclear translocator-like


chr2_-_190044330 1.790 NM_000393
COL5A2
collagen, type V, alpha 2
chr8_-_101964236 1.763 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr4_+_47487230 1.712 NM_020453
ATP10D
ATPase, class V, type 10D
chr11_+_13299372 1.703 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr11_+_13299376 1.687 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chrX_-_13835012 1.662 GPM6B
glycoprotein M6B
chr12_-_47473424 1.654 NM_001143668
NM_181847
AMIGO2

adhesion molecule with Ig-like domain 2

chr11_+_13299349 1.635 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr15_+_41245635 1.619 NM_001142776
NM_024111
CHAC1

ChaC, cation transport regulator homolog 1 (E. coli)

chr3_+_50273645 1.595 NM_002070
GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr16_+_82660390 1.548 NM_001220488
NM_001220489
NM_001220490
NM_001220491
NM_001220492
NM_001257
CDH13





cadherin 13, H-cadherin (heart)





chr16_+_82660573 1.519 CDH13
cadherin 13, H-cadherin (heart)
chr11_+_13299391 1.516 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr17_+_76183397 1.511 NM_001010982
NM_001145526
AFMID

arylformamidase

chr3_+_50273745 1.508 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr10_+_17270469 1.486 VIM
vimentin
chr3_+_50273635 1.484 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr3_+_50273575 1.482 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr12_+_4430346 1.446 NM_020375
C12orf5
chromosome 12 open reading frame 5
chr9_+_75766777 1.434 NM_000700
ANXA1
annexin A1
chr3_+_50273648 1.394 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr8_-_49833823 1.376 NM_003068
SNAI2
snail homolog 2 (Drosophila)
chrX_+_103217192 1.375 NM_194324
TMSB15B
thymosin beta 15B
chr11_+_13299329 1.359 ARNTL
aryl hydrocarbon receptor nuclear translocator-like
chr19_+_41284068 1.353 NM_016154
RAB4B
RAB4B, member RAS oncogene family
chr12_+_79258588 1.325 SYT1
synaptotagmin I
chr22_-_19511777 1.319 CLDN5
claudin 5
chr9_+_75766794 1.283 ANXA1
annexin A1
chr14_-_52535765 1.281 NID2
nidogen 2 (osteonidogen)
chr8_-_41166931 1.272 NM_003012
SFRP1
secreted frizzled-related protein 1
chr14_-_52535737 1.271 NID2
nidogen 2 (osteonidogen)
chr3_+_48488180 1.254 NM_032166
NM_130384
TREX1
ATRIP

three prime repair exonuclease 1
ATR interacting protein

chr14_-_52535711 1.237 NID2
nidogen 2 (osteonidogen)
chr5_-_127873734 1.236 NM_001999
FBN2
fibrillin 2
chr2_-_179672056 1.230 NM_003319
NM_133378
NM_133379
NM_133432
NM_133437
TTN




titin




chr7_+_65670256 1.229 NM_003596
TPST1
tyrosylprotein sulfotransferase 1
chr1_-_153363544 1.210 NM_002964
S100A8
S100 calcium binding protein A8
chr9_+_79093256 1.209 NM_001097635
GCNT1
glucosaminyl (N-acetyl) transferase 1, core 2
chr1_-_68697997 1.204 NM_001002292
NM_001193334
NM_024911
WLS


wntless homolog (Drosophila)


chr16_+_68679229 1.202 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr3_+_50273674 1.202 GNAI2
guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2
chr14_-_52535945 1.187 NM_007361
NID2
nidogen 2 (osteonidogen)
chr8_-_101964268 1.137 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chrX_+_102631267 1.125 NM_206915
NM_206917
NGFRAP1

nerve growth factor receptor (TNFRSF16) associated protein 1

chr1_+_181057835 1.116 IER5
immediate early response 5
chr9_-_35072545 1.111 VCP
valosin containing protein
chr1_+_101702304 1.097 NM_001400
S1PR1
sphingosine-1-phosphate receptor 1
chrX_+_64887593 1.095 MSN
moesin
chr16_+_68679198 1.080 CDH3
cadherin 3, type 1, P-cadherin (placental)
chr15_-_83876769 1.075 HDGFRP3
hepatoma-derived growth factor, related protein 3
chr9_+_36190885 1.039 CLTA
clathrin, light chain A
chr2_-_86116016 1.026 NM_003896
ST3GAL5
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chrX_+_107334896 1.023 NM_052936
NM_178270
ATG4A

ATG4 autophagy related 4 homolog A (S. cerevisiae)

chr22_-_17640168 1.021 NM_033070
CECR5
cat eye syndrome chromosome region, candidate 5
chr22_-_17640153 1.021 CECR5
cat eye syndrome chromosome region, candidate 5
chr22_-_17640076 1.005 CECR5
cat eye syndrome chromosome region, candidate 5
chr10_+_102792166 0.986 SFXN3
sideroflexin 3
chr8_+_42010463 0.976 NM_001134296
NM_006803
AP3M2

adaptor-related protein complex 3, mu 2 subunit

chr4_+_78078394 0.970 CCNG2
cyclin G2
chr16_+_31484497 0.963 NM_015927
TGFB1I1
transforming growth factor beta 1 induced transcript 1
chr8_-_42065193 0.957 NM_000930
NM_033011
PLAT

plasminogen activator, tissue

chr8_-_101964197 0.955 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chrX_+_102631408 0.954 NGFRAP1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr9_+_36190928 0.950 CLTA
clathrin, light chain A
chr8_-_98290072 0.946 TSPYL5
TSPY-like 5
chr10_+_102792161 0.940 SFXN3
sideroflexin 3
chr9_+_116327301 0.924 NM_134427
RGS3
regulator of G-protein signaling 3
chr3_-_69435223 0.918 FRMD4B
FERM domain containing 4B
chr4_+_78078332 0.918 NM_004354
CCNG2
cyclin G2
chr10_-_101690655 0.910 DNMBP
dynamin binding protein
chr18_+_21452981 0.909 NM_000227
NM_001127718
LAMA3

laminin, alpha 3

chr9_-_35072643 0.902 NM_007126
VCP
valosin containing protein
chr1_-_94147201 0.885 NM_003567
BCAR3
breast cancer anti-estrogen resistance 3
chr12_+_79258517 0.885 SYT1
synaptotagmin I
chr1_-_207205996 0.884 NM_001083924
NM_023938
C1orf116

chromosome 1 open reading frame 116

chr9_+_33624214 0.883 ANXA2P2
annexin A2 pseudogene 2
chr1_-_95392449 0.881 CNN3
calponin 3, acidic
chr9_-_35072596 0.879 VCP
valosin containing protein
chr8_-_101964248 0.874 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr14_-_91526912 0.872 NM_004755
NM_182398
RPS6KA5

ribosomal protein S6 kinase, 90kDa, polypeptide 5

chr7_-_134143804 0.870 AKR1B1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr7_+_98246595 0.862 NM_002523
NPTX2
neuronal pentraxin II
chr1_-_46598250 0.853 NM_003629
NM_001114172
PIK3R3

phosphoinositide-3-kinase, regulatory subunit 3 (gamma)

chr19_+_41284161 0.840 RAB4B-EGLN2
RAB4B
RAB4B-EGLN2 readthrough
RAB4B, member RAS oncogene family
chr12_-_49582800 0.837 NM_006009
TUBA1A
tubulin, alpha 1a
chr8_-_77912296 0.833 NM_000318
NM_001079867
PEX2

peroxisomal biogenesis factor 2

chr9_+_36190852 0.832 NM_001076677
NM_001184760
NM_001184761
NM_001184762
NM_001833
NM_007096
CLTA





clathrin, light chain A





chr9_+_36190956 0.825 CLTA
clathrin, light chain A
chr17_-_3571819 0.818 TAX1BP3
Tax1 (human T-cell leukemia virus type I) binding protein 3
chr5_+_102201713 0.815 PAM
peptidylglycine alpha-amidating monooxygenase
chr20_-_32307889 0.814 NM_007238
NM_183397
PXMP4

peroxisomal membrane protein 4, 24kDa

chr9_+_82186846 0.812 NM_007005
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr12_+_79258448 0.805 NM_005639
SYT1
synaptotagmin I
chr17_-_7307413 0.801 NM_152766
C17orf61-PLSCR3
C17orf61
C17orf61-PLSCR3 readthrough
chromosome 17 open reading frame 61
chrX_-_101771641 0.800 NM_021992
TMSB15A
TMSB15B
thymosin beta 15a
thymosin beta 15B
chr11_+_35160832 0.786 CD44
CD44 molecule (Indian blood group)
chr7_-_134143864 0.785 NM_001628
AKR1B1
aldo-keto reductase family 1, member B1 (aldose reductase)
chr5_+_102201526 0.784 NM_000919
NM_001177306
NM_138766
NM_138821
NM_138822
PAM




peptidylglycine alpha-amidating monooxygenase




chr10_+_11060105 0.780 CELF2
CUGBP, Elav-like family member 2
chr14_-_55658205 0.765 NM_001146015
NM_014750
DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chr9_-_99801365 0.765 NM_001333
CTSL2
cathepsin L2
chr7_-_94285477 0.762 NM_001099400
NM_001099401
NM_003919
SGCE


sarcoglycan, epsilon


chr8_-_101964258 0.748 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr7_-_94285426 0.745 SGCE
sarcoglycan, epsilon
chr12_+_54447660 0.743 NM_153633
HOXC4
HOXC6
homeobox C4
homeobox C6
chr14_-_100842623 0.742 WARS
tryptophanyl-tRNA synthetase
chr13_+_37006408 0.741 NM_001111045
NM_003914
CCNA1

cyclin A1

chr7_-_94285372 0.739 SGCE
sarcoglycan, epsilon
chr8_-_101964247 0.731 YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr1_+_181057637 0.729 NM_016545
IER5
immediate early response 5
chr17_-_5389480 0.726 NM_016041
DERL2
Der1-like domain family, member 2
chr1_-_103574051 0.724 NM_001190709
NM_001854
NM_080629
NM_080630
COL11A1



collagen, type XI, alpha 1



chr8_+_26435339 0.721 NM_001386
DPYSL2
dihydropyrimidinase-like 2
chr2_-_130886794 0.720 NM_001099771
POTEF
POTE ankyrin domain family, member F
chr19_-_45926819 0.719 NM_202001
ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr1_+_236305831 0.718 NM_003272
GPR137B
G protein-coupled receptor 137B
chr12_-_21654484 0.718 NM_002907
NM_032941
RECQL

RecQ protein-like (DNA helicase Q1-like)

chr9_+_36191015 0.716 CLTA
clathrin, light chain A
chr13_+_37006628 0.712 CCNA1
cyclin A1
chr9_+_137533643 0.712 NM_000093
COL5A1
collagen, type V, alpha 1
chr10_+_71075609 0.710 NM_033496
HK1
hexokinase 1
chr20_+_44441334 0.705 UBE2C
ubiquitin-conjugating enzyme E2C
chr5_+_140729723 0.703 NM_018922
NM_032095
PCDHGB1

protocadherin gamma subfamily B, 1

chr1_-_209979388 0.695 NM_001206696
NM_006147
IRF6

interferon regulatory factor 6

chr20_+_44441247 0.690 NM_007019
NM_181799
NM_181800
NM_181802
NM_181803
UBE2C




ubiquitin-conjugating enzyme E2C




chr9_+_116207010 0.681 NM_144488
RGS3
regulator of G-protein signaling 3
chr17_-_33759518 0.680 NM_018042
SLFN12
schlafen family member 12
chr10_-_91011562 0.678 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr18_+_29027731 0.677 NM_001944
DSG3
desmoglein 3
chr9_-_99801924 0.673 NM_001201575
CTSL2
cathepsin L2
chr18_+_47088400 0.671 NM_006033
LIPG
lipase, endothelial
chr2_-_45236521 0.670 NM_016932
SIX2
SIX homeobox 2
chr10_-_91102430 0.669 LIPA
lipase A, lysosomal acid, cholesterol esterase
chr11_-_4629371 0.669 NM_018073
TRIM68
tripartite motif containing 68
chr3_+_172468469 0.661 ECT2
epithelial cell transforming sequence 2 oncogene
chr6_-_32920812 0.660 NM_006120
HLA-DMA
major histocompatibility complex, class II, DM alpha
chr12_+_54332575 0.658 NM_017410
HOXC13
homeobox C13
chr11_-_122932806 0.657 HSPA8
heat shock 70kDa protein 8
chr14_-_100841793 0.655 WARS
tryptophanyl-tRNA synthetase
chr4_-_90759446 0.648 NM_001146055
SNCA
synuclein, alpha (non A4 component of amyloid precursor)
chr19_-_48018163 0.646 NAPA
N-ethylmaleimide-sensitive factor attachment protein, alpha
chr1_+_213123853 0.644 NM_001136474
NM_001136475
NM_024749
VASH2


vasohibin 2


chr5_+_151151483 0.640 G3BP1
GTPase activating protein (SH3 domain) binding protein 1
chr6_-_112194648 0.637 NM_002037
FYN
FYN oncogene related to SRC, FGR, YES
chr11_-_119293848 0.629 THY1
Thy-1 cell surface antigen
chr1_-_151966303 0.628 S100A10
S100 calcium binding protein A10
chr14_-_104181744 0.628 NM_001100118
NM_001100119
NM_005432
XRCC3


X-ray repair complementing defective repair in Chinese hamster cells 3


chr2_+_9346909 0.627 ASAP2
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr2_+_241375030 0.626 NM_002081
GPC1
glypican 1
chr1_+_151032683 0.621 MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr3_-_197463713 0.620 NM_014687
KIAA0226
KIAA0226
chr6_+_36644236 0.619 NM_001220777
NM_078467
CDKN1A

cyclin-dependent kinase inhibitor 1A (p21, Cip1)

chr12_-_21654206 0.618 RECQL
RecQ protein-like (DNA helicase Q1-like)
chr3_-_49761293 0.617 NM_013334
NM_021971
GMPPB

GDP-mannose pyrophosphorylase B

chr5_+_140762401 0.615 NM_018920
NM_032087
PCDHGA7

protocadherin gamma subfamily A, 7

chr4_-_114900802 0.613 NM_024590
ARSJ
arylsulfatase family, member J
chr8_-_101964334 0.606 NM_145690
YWHAZ
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr3_-_98620452 0.605 NM_080927
DCBLD2
discoidin, CUB and LCCL domain containing 2
chr14_-_100842676 0.600 NM_173701
NM_213645
WARS

tryptophanyl-tRNA synthetase

chr17_+_5389864 0.600 MIS12
MIS12, MIND kinetochore complex component, homolog (S. pombe)
chr8_+_26435466 0.598 DPYSL2
dihydropyrimidinase-like 2
chr1_-_109584589 0.596 NM_001142550
NM_001142551
NM_014969
WDR47


WD repeat domain 47


chr6_+_29855506 0.596


chr14_-_100842637 0.596 WARS
tryptophanyl-tRNA synthetase
chr20_+_44441671 0.595 NM_181801
UBE2C
ubiquitin-conjugating enzyme E2C
chr1_+_101702561 0.591 S1PR1
sphingosine-1-phosphate receptor 1
chr19_+_52693334 0.578 PPP2R1A
protein phosphatase 2, regulatory subunit A, alpha
chr16_-_84651639 0.568 NM_021149
COTL1
coactosin-like 1 (Dictyostelium)
chr1_-_151966276 0.562 S100A10
S100 calcium binding protein A10
chr9_-_35115844 0.561 NM_025182
FAM214B
family with sequence similarity 214, member B
chr3_+_51422691 0.559 NM_006010
MANF
mesencephalic astrocyte-derived neurotrophic factor
chr16_+_57278979 0.557 NM_012106
ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr10_-_3827418 0.557 NM_001160124
NM_001160125
NM_001300
KLF6


Kruppel-like factor 6


chr11_-_119294242 0.555 NM_006288
THY1
Thy-1 cell surface antigen
chr12_-_28122884 0.553 NM_198964
NM_198966
PTHLH

parathyroid hormone-like hormone

chr11_-_14380591 0.551 NM_012250
RRAS2
related RAS viral (r-ras) oncogene homolog 2
chr1_-_103573894 0.551 COL11A1
collagen, type XI, alpha 1
chr9_+_34329503 0.549 NM_001161
NM_001244390
NM_147172
NM_147173
NUDT2



nudix (nucleoside diphosphate linked moiety X)-type motif 2



chr19_-_45926759 0.548 ERCC1
excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
chr13_-_67804432 0.539 NM_020403
NM_203487
PCDH9

protocadherin 9

chrX_-_23761396 0.539 NM_001033583
NM_001037171
ACOT9

acyl-CoA thioesterase 9

chr1_-_68962679 0.539 DEPDC1
DEP domain containing 1
chr7_-_86848818 0.538 NM_024315
C7orf23
chromosome 7 open reading frame 23
chr17_+_48133331 0.534 NM_002204
NM_005501
ITGA3

integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)

chr9_+_34989637 0.533 NM_001135004
NM_012266
DNAJB5

DnaJ (Hsp40) homolog, subfamily B, member 5

chr21_+_47744032 0.533 NM_006031
PCNT
pericentrin
chr18_-_45457454 0.532 NM_001003652
NM_001135937
SMAD2

SMAD family member 2


Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.