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• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: LMO2.p2

Z-value: 1.898

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr15_+_89182038	3.385	NM_002201	ISG20	interferon stimulated exonuclease gene 20kDa
chr5_+_169064238	2.638	NM_004946	DOCK2	dedicator of cytokinesis 2
chr16_+_23847321	2.357		PRKCB	protein kinase C, beta
chr16_+_23847271	2.300	NM_002738 NM_212535	PRKCB	protein kinase C, beta
chrX_-_118827060	2.169		SEPT6	septin 6
chr22_+_22697538	2.116
chr6_-_32551993	2.053		HLA-DRB1 HLA-DRB4 HLA-DRB5	major histocompatibility complex, class II, DR beta 1 major histocompatibility complex, class II, DR beta 4 major histocompatibility complex, class II, DR beta 5
chr11_-_33890931	2.039		LMO2	LIM domain only 2 (rhombotin-like 1)
chr17_+_76164624	2.026	NM_004710	SYNGR2	synaptogyrin 2
chr22_+_22550112	1.933
chr16_+_23847359	1.896		PRKCB	protein kinase C, beta
chr5_+_169064274	1.858		DOCK2	dedicator of cytokinesis 2
chr14_+_31343642	1.764	NM_001135058 NM_004086	COCH	coagulation factor C homolog, cochlin (Limulus polyphemus)
chr14_-_106208695	1.762
chr5_-_94620277	1.705	NM_024717	MCTP1	multiple C2 domains, transmembrane 1
chr1_-_111746917	1.676		DENND2D	DENN/MADD domain containing 2D
chr14_-_106405633	1.620		IGHM	immunoglobulin heavy constant mu
chr14_-_107131217	1.577		IGHA1	immunoglobulin heavy constant alpha 1
chr14_-_107113943	1.577		IGHA1 IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chr14_-_106208537	1.554
chr19_+_18284619	1.524		IFI30	interferon, gamma-inducible protein 30
chr22_+_24823529	1.438	NM_000675	ADORA2A	adenosine A2a receptor
chr19_+_18284631	1.432		IFI30	interferon, gamma-inducible protein 30
chr14_-_106092256	1.425		IGHG4	immunoglobulin heavy constant gamma 4 (G4m marker)
chr2_+_79740059	1.408	NM_001164883 NM_004389	CTNNA2	catenin (cadherin-associated protein), alpha 2
chr11_-_33891258	1.395		LMO2	LIM domain only 2 (rhombotin-like 1)
chrX_-_118827322	1.367	NM_015129 NM_145799 NM_145800 NM_145802	SEPT6	septin 6
chr2_+_79740171	1.363		CTNNA2	catenin (cadherin-associated protein), alpha 2
chr22_+_23010757	1.362
chr16_+_81812899	1.360		PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr5_+_156693051	1.346	NM_001037333 NM_001037332	CYFIP2	cytoplasmic FMR1 interacting protein 2
chr16_+_81812925	1.340		PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr2_+_65216526	1.319		SLC1A4	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr16_+_81812897	1.313	NM_002661	PLCG2	phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr15_-_38856830	1.307	NM_001128602 NM_005739	RASGRP1	RAS guanyl releasing protein 1 (calcium and DAG-regulated)
chr4_-_36245893	1.273	NM_015230	ARAP2	ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_+_60223281	1.265	NM_021950 NM_152866	MS4A1	membrane-spanning 4-domains, subfamily A, member 1
chr14_-_106237486	1.261
chr14_-_107170400	1.235		IGHV4-31 IGHV1-69 IGHA1 IGHG1 IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy variable 1-69 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chrX_-_118827155	1.203		SEPT6	septin 6
chr19_-_11689765	1.203	NM_001111035 NM_001111036	ACP5	acid phosphatase 5, tartrate resistant
chr4_-_42658883	1.177	NM_001105529 NM_006095	ATP8A1	ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr14_-_106539099	1.173		IGHA1 IGHG1 IGHG3	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker)
chr14_-_106237675	1.172		IGHM	immunoglobulin heavy constant mu
chr9_+_116226006	1.169	NM_017790	RGS3	regulator of G-protein signaling 3
chr1_-_160990862	1.147		F11R	F11 receptor
chr14_-_106573348	1.122		IGHV4-31 IGHA1 IGHA2 IGHG1 IGHG3 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 3 (G3m marker) immunoglobulin heavy constant mu
chr14_-_106518424	1.112		IGH@ IGHA1 IGHG1 IGHG2 IGHM	immunoglobulin heavy locus immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 2 (G2m marker) immunoglobulin heavy constant mu
chr19_-_11689591	1.112	NM_001111034	ACP5	acid phosphatase 5, tartrate resistant
chr20_+_37434294	1.102	NM_001172735 NM_015568	PPP1R16B	protein phosphatase 1, regulatory subunit 16B
chr14_-_106967528	1.083		IGHA1 IGHA2 IGHG1 IGHM	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr10_+_11060105	1.079		CELF2	CUGBP, Elav-like family member 2
chr7_-_994008	1.064		ADAP1	ArfGAP with dual PH domains 1
chr6_+_31539875	1.052	NM_001159740	LTA	lymphotoxin alpha (TNF superfamily, member 1)
chr2_+_65216482	1.036	NM_003038	SLC1A4	solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr7_-_37488894	1.035	NM_001206480	ELMO1	engulfment and cell motility 1
chr1_+_12227050	1.027	NM_001066	TNFRSF1B	tumor necrosis factor receptor superfamily, member 1B
chr14_-_106994001	1.011		IGHV3-48 IGH@ IGHA1 IGHM	immunoglobulin heavy variable 3-48 immunoglobulin heavy locus immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant mu
chr12_-_117537090	1.000	NM_001168325 NM_017899	TESC	tescalcin
chr2_-_163174816	0.993	NM_022168	IFIH1	interferon induced with helicase C domain 1
chr17_-_38721701	0.990	NM_001838	CCR7	chemokine (C-C motif) receptor 7
chr5_-_88199868	0.987	NM_001131005 NM_001193347	MEF2C	myocyte enhancer factor 2C
chr19_+_14544216	0.984		PKN1	protein kinase N1
chr14_-_107013474	0.982		IGHA1 IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chr2_-_160761192	0.980		LY75-CD302 LY75	LY75-CD302 readthrough lymphocyte antigen 75
chrX_-_118827116	0.980		SEPT6	septin 6
chr7_+_73624328	0.980		LAT2	linker for activation of T cells family, member 2
chr16_-_89043215	0.971	NM_005187	CBFA2T3	core-binding factor, runt domain, alpha subunit 2; translocated to, 3
chr7_+_73624347	0.970		LAT2	linker for activation of T cells family, member 2
chr19_+_1071208	0.966		HMHA1	histocompatibility (minor) HA-1
chr14_-_23288912	0.957	NM_001126106	SLC7A7	solute carrier family 7 (amino acid transporter light chain, y+L system), member 7
chr8_+_6566153	0.928		AGPAT5	1-acylglycerol-3-phosphate O-acyltransferase 5 (lysophosphatidic acid acyltransferase, epsilon)
chr10_+_11060069	0.926		CELF2	CUGBP, Elav-like family member 2
chr9_-_123691442	0.916	NM_001190945	TRAF1	TNF receptor-associated factor 1
chr7_+_73624086	0.909	NM_014146 NM_032463 NM_032464	LAT2	linker for activation of T cells family, member 2
chr6_-_90121911	0.906		RRAGD	Ras-related GTP binding D
chr22_+_37257004	0.905	NM_000631 NM_013416	NCF4	neutrophil cytosolic factor 4, 40kDa
chr19_+_42381189	0.895	NM_001783 NM_021601	CD79A	CD79a molecule, immunoglobulin-associated alpha
chr22_+_22712091	0.889		IGLV1-44 IGL@	immunoglobulin lambda variable 1-44 immunoglobulin lambda locus
chr14_-_55369163	0.883	NM_000161 NM_001024024 NM_001024070 NM_001024071	GCH1	GTP cyclohydrolase 1
chr6_-_3227776	0.875	NM_178012	TUBB2B	tubulin, beta 2B class IIb
chr10_-_115613858	0.860	NM_014881	DCLRE1A	DNA cross-link repair 1A
chr3_+_16926451	0.856	NM_001144382	PLCL2	phospholipase C-like 2
chr17_+_39240412	0.854	NM_033061	KRTAP4-7	keratin associated protein 4-7
chr2_+_170590241	0.840	NM_144711	KLHL23	kelch-like 23 (Drosophila)
chr3_-_13461802	0.838	NM_024923	NUP210	nucleoporin 210kDa
chr3_-_182833859	0.837		MCCC1	methylcrotonoyl-CoA carboxylase 1 (alpha)
chr1_-_27961623	0.821	NM_005248	FGR	Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog
chr9_-_92112887	0.819		SEMA4D	sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr12_-_92539614	0.818	NM_001731	BTG1	B-cell translocation gene 1, anti-proliferative
chr9_+_71320105	0.816	NM_003558	PIP5K1B	phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr8_-_28243941	0.808	NM_018660	ZNF395	zinc finger protein 395
chr5_+_126112847	0.806		LMNB1	lamin B1
chr4_+_89378234	0.801	NM_016323	HERC5	hect domain and RLD 5
chr19_+_13875352	0.795		MRI1	methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)
chr12_+_7055736	0.794	NM_080548	PTPN6	protein tyrosine phosphatase, non-receptor type 6
chr4_+_40198526	0.785	NM_004310	RHOH	ras homolog gene family, member H
chr20_+_61273823	0.780		SLCO4A1	solute carrier organic anion transporter family, member 4A1
chr2_-_242089393	0.777	NM_001252120	PASK	PAS domain containing serine/threonine kinase
chr22_-_37882214	0.777	NM_001166343 NM_002405	MFNG	MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr12_-_63328857	0.771		PPM1H	protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr14_-_106471439	0.759		IGHA1 IGHG1 IGHM	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant mu
chr19_+_18284578	0.756	NM_006332	IFI30	interferon, gamma-inducible protein 30
chr19_-_7764283	0.750	NM_001207019	FCER2	Fc fragment of IgE, low affinity II, receptor for (CD23)
chr10_-_23003036	0.747		PIP4K2A	phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr17_-_46507599	0.743		SKAP1	src kinase associated phosphoprotein 1
chr20_+_61273786	0.737	NM_016354	SLCO4A1	solute carrier organic anion transporter family, member 4A1
chr7_+_150065859	0.735	NM_001099695 NM_001099696 NM_013400	REPIN1	replication initiator 1
chr2_+_95691428	0.733	NM_002371 NM_022438 NM_022439 NM_022440	MAL	mal, T-cell differentiation protein
chr15_-_60884615	0.730	NM_134262	RORA	RAR-related orphan receptor A
chr10_-_98945662	0.729	NM_003061	SLIT1	slit homolog 1 (Drosophila)
chr3_-_124930192	0.720	NM_001195483	SLC12A8	solute carrier family 12 (potassium/chloride transporters), member 8
chr14_-_106780535	0.717		IGHA1 IGHA2 IGHD IGHG1	immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant delta immunoglobulin heavy constant gamma 1 (G1m marker)
chr12_-_63328663	0.715	NM_020700	PPM1H	protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr21_+_42797977	0.709	NM_002462 NM_001178046	MX1	myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)
chr2_+_231090443	0.703	NM_001005176 NM_007237	SP140	SP140 nuclear body protein
chr5_-_138725544	0.703	NM_016459	MZB1	marginal zone B and B1 cell-specific protein
chr6_+_31540092	0.702	NM_000595	LTA	lymphotoxin alpha (TNF superfamily, member 1)
chr7_-_37488554	0.702	NM_014800	ELMO1	engulfment and cell motility 1
chr6_-_32497925	0.698	NM_002125	HLA-DRB5	major histocompatibility complex, class II, DR beta 5
chr17_+_40440481	0.697		STAT5A	signal transducer and activator of transcription 5A
chr6_-_90121966	0.689	NM_021244	RRAGD	Ras-related GTP binding D
chr8_-_103136486	0.684	NM_001040624 NM_001040625 NM_001040626 NM_001040627 NM_001040628 NM_001040629	NCALD	neurocalcin delta
chr6_-_90121656	0.683		RRAGD	Ras-related GTP binding D
chr3_+_53880590	0.681		IL17RB	interleukin 17 receptor B
chr17_-_76836852	0.680	NM_025090	USP36	ubiquitin specific peptidase 36
chr2_+_191273012	0.673	NM_017694	MFSD6	major facilitator superfamily domain containing 6
chr19_-_6670078	0.671		TNFSF14	tumor necrosis factor (ligand) superfamily, member 14
chr1_-_193028389	0.668		UCHL5	ubiquitin carboxyl-terminal hydrolase L5
chr14_-_106877689	0.666		IGHV4-31 IGH@ IGHA1 IGHA2 IGHG1 IGHG4 IGHM	immunoglobulin heavy variable 4-31 immunoglobulin heavy locus immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant alpha 2 (A2m marker) immunoglobulin heavy constant gamma 1 (G1m marker) immunoglobulin heavy constant gamma 4 (G4m marker) immunoglobulin heavy constant mu
chr7_-_37488408	0.663		ELMO1	engulfment and cell motility 1
chr2_+_163200582	0.655	NM_012198	GCA	grancalcin, EF-hand calcium binding protein
chr2_-_160761266	0.651	NM_001198759 NM_001198760 NM_002349	LY75-CD302 LY75	LY75-CD302 readthrough lymphocyte antigen 75
chr10_+_89623091	0.650	NM_000314	PTEN	phosphatase and tensin homolog
chr18_+_29078026	0.649	NM_001943	DSG2	desmoglein 2
chr1_-_193028524	0.638		UCHL5	ubiquitin carboxyl-terminal hydrolase L5
chr22_+_44422183	0.634	NM_001243386	PARVB	parvin, beta
chrX_+_78200828	0.627	NM_014499 NM_198333	P2RY10	purinergic receptor P2Y, G-protein coupled, 10
chr15_-_45670955	0.625	NM_001482	GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr5_-_150603615	0.624		CCDC69	coiled-coil domain containing 69
chr19_+_13875345	0.623		MRI1	methylthioribose-1-phosphate isomerase homolog (S. cerevisiae)
chr7_-_994259	0.621	NM_006869	ADAP1	ArfGAP with dual PH domains 1
chr3_+_57261729	0.621	NM_012096	APPL1	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1
chr8_-_80993009	0.617	NM_001025252	TPD52	tumor protein D52
chr20_-_23066828	0.616	NM_012072	CD93	CD93 molecule
chr22_+_22550159	0.612		IGLV6-57	immunoglobulin lambda variable 6-57
chr8_+_56792399	0.612		LYN	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog
chr17_+_65822242	0.612		BPTF	bromodomain PHD finger transcription factor
chr15_-_45670624	0.611		GATM	glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chrX_+_129305553	0.609	NM_004794	RAB33A	RAB33A, member RAS oncogene family
chr12_+_54891539	0.605		NCKAP1L	NCK-associated protein 1-like
chr5_+_68788387	0.603	NM_001205254	OCLN	occludin
chr3_-_13461725	0.601		NUP210	nucleoporin 210kDa
chr3_+_53880563	0.599	NM_018725	IL17RB	interleukin 17 receptor B
chr9_+_117373622	0.597	NM_153045	C9orf91	chromosome 9 open reading frame 91
chr3_-_171177851	0.597	NM_001161560 NM_001161561 NM_001161562 NM_001161563 NM_001161564 NM_001161565 NM_001161566 NM_015028	TNIK	TRAF2 and NCK interacting kinase
chrX_-_39956655	0.596	NM_001123385 NM_017745	BCOR	BCL6 corepressor
chr8_-_28243589	0.593		ZNF395	zinc finger protein 395
chr19_+_7702010	0.593		STXBP2	syntaxin binding protein 2
chr3_-_197282805	0.593	NM_004051 NM_203314	BDH1	3-hydroxybutyrate dehydrogenase, type 1
chr1_+_6094342	0.587	NM_001199860	KCNAB2	potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr1_-_24194760	0.586	NM_000147	FUCA1	fucosidase, alpha-L- 1, tissue
chr8_-_103137134	0.585	NM_001040630	NCALD	neurocalcin delta
chr17_-_28619183	0.583	NM_000386	BLMH	bleomycin hydrolase
chr20_+_42295747	0.581		MYBL2	v-myb myeloblastosis viral oncogene homolog (avian)-like 2
chr11_+_7535213	0.570		PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr9_+_93564099	0.569		SYK	spleen tyrosine kinase
chr11_-_33891485	0.569	NM_001142315	LMO2	LIM domain only 2 (rhombotin-like 1)
chr2_-_216878314	0.565	NM_018000	MREG	melanoregulin
chr9_-_35650852	0.564	NM_014450	SIT1	signaling threshold regulating transmembrane adaptor 1
chr15_+_74833517	0.562	NM_006465	ARID3B	AT rich interactive domain 3B (BRIGHT-like)
chr17_+_67410825	0.558	NM_002758	MAP2K6	mitogen-activated protein kinase kinase 6
chr2_+_170550949	0.557	NM_001199290 NM_001008489 NM_001199285 NM_001199286 NM_001199287 NM_001199288	PHOSPHO2-KLHL23 PHOSPHO2	PHOSPHO2-KLHL23 readthrough phosphatase, orphan 2
chrX_+_131157635	0.551	NM_001042452	MST4	serine/threonine protein kinase MST4
chrX_-_107018889	0.549		TSC22D3	TSC22 domain family, member 3
chr15_-_93198602	0.547	NM_207446	FAM174B	family with sequence similarity 174, member B
chr10_-_116527955	0.545		ABLIM1	actin binding LIM protein 1
chr1_+_36771962	0.545	NM_001162530	SH3D21	SH3 domain containing 21
chr17_-_54991352	0.543		TRIM25	tripartite motif containing 25
chr12_+_54891522	0.543		NCKAP1L	NCK-associated protein 1-like
chr6_+_106534188	0.542	NM_001198	PRDM1	PR domain containing 1, with ZNF domain
chr17_+_65822206	0.542		BPTF	bromodomain PHD finger transcription factor
chr11_-_22647329	0.540	NM_022725	FANCF	Fanconi anemia, complementation group F
chr20_+_42295708	0.539	NM_002466	MYBL2	v-myb myeloblastosis viral oncogene homolog (avian)-like 2
chr8_-_81083660	0.535	NM_001025253 NM_005079	TPD52	tumor protein D52
chr14_-_107083398	0.533		IGH@ IGHA1 IGHG1	immunoglobulin heavy locus immunoglobulin heavy constant alpha 1 immunoglobulin heavy constant gamma 1 (G1m marker)
chr1_-_32403888	0.531		PTP4A2	protein tyrosine phosphatase type IVA, member 2
chr19_+_7702020	0.531		STXBP2	syntaxin binding protein 2
chr16_+_85646923	0.530	NM_014615	KIAA0182	KIAA0182
chr11_+_7535000	0.529	NM_003621	PPFIBP2	PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr19_+_7701976	0.527	NM_001127396 NM_006949	STXBP2	syntaxin binding protein 2
chr6_+_16129321	0.526		MYLIP	myosin regulatory light chain interacting protein
chr1_+_158801105	0.524	NM_002432	MNDA	myeloid cell nuclear differentiation antigen
chr1_+_32739711	0.523	NM_001042771	LCK	lymphocyte-specific protein tyrosine kinase
chr6_+_106534210	0.521		PRDM1	PR domain containing 1, with ZNF domain
chr2_-_242088822	0.521	NM_001252119 NM_001252122 NM_001252124 NM_015148	PASK	PAS domain containing serine/threonine kinase
chr10_-_103347882	0.520		POLL	polymerase (DNA directed), lambda
chr10_+_92980322	0.520	NM_032373	PCGF5	polycomb group ring finger 5
chr11_+_71249070	0.519	NM_021046	KRTAP5-8	keratin associated protein 5-8
chr1_-_32403975	0.515	NM_080391	PTP4A2	protein tyrosine phosphatase type IVA, member 2

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
5.95	1.88e-08	GO:0002376	immune system process
8.00	2.34e-08	GO:0006955	immune response
2.11	1.71e-04	GO:0050896	response to stimulus
3.49	1.71e-03	GO:0048583	regulation of response to stimulus
26.32	4.28e-03	GO:0019882	antigen processing and presentation
5.26	9.45e-03	GO:0002682	regulation of immune system process
21.06	1.04e-02	GO:0032102	negative regulation of response to external stimulus
113.97	3.65e-02	GO:0060134	prepulse inhibition
15.22	3.74e-02	GO:0050851	antigen receptor-mediated signaling pathway
29.33	4.08e-02	GO:0050728	negative regulation of inflammatory response
7.20	4.45e-02	GO:0031347	regulation of defense response

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
5.80	2.47e-05	GO:0005624	membrane fraction
5.62	3.54e-05	GO:0005626	insoluble fraction
2.44	6.40e-04	GO:0071944	cell periphery
4.25	6.75e-04	GO:0000267	cell fraction
2.35	2.22e-03	GO:0005886	plasma membrane

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
59.85	7.94e-10	GO:0003823	antigen binding