Motif ID: PATZ1.p2

Z-value: 1.966


Transcription factors associated with PATZ1.p2:

Gene SymbolEntrez IDGene Name
PATZ1 23598 POZ (BTB) and AT hook containing zinc finger 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
PATZ1chr22_-_317423290.871.0e-05Click!


Activity profile for motif PATZ1.p2.

activity profile for motif PATZ1.p2


Sorted Z-values histogram for motif PATZ1.p2

Sorted Z-values for motif PATZ1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of PATZ1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_198060 4.201 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr6_+_37137882 3.708 NM_001243186
NM_002648
PIM1

pim-1 oncogene

chrY_+_148060 3.687 NM_018390
PLCXD1
phosphatidylinositol-specific phospholipase C, X domain containing 1
chr16_-_52580805 3.299 NM_001080430
TOX3
TOX high mobility group box family member 3
chr1_-_32801606 2.600 NM_023009
MARCKSL1
MARCKS-like 1
chr7_-_158380360 2.524 NM_002847
NM_130842
NM_130843
PTPRN2


protein tyrosine phosphatase, receptor type, N polypeptide 2


chr20_-_3154169 2.217 ProSAPiP1
ProSAPiP1 protein
chr17_-_79008372 2.011 FLJ90757
uncharacterized LOC440465
chr19_-_18717577 1.959 CRLF1
cytokine receptor-like factor 1
chr19_-_18717631 1.955 NM_004750
CRLF1
cytokine receptor-like factor 1
chr16_-_29910340 1.944 NM_001114099
NM_001114100
NM_001243332
NM_001243333
NM_012410
NM_201575
SEZ6L2





seizure related 6 homolog (mouse)-like 2





chr5_+_176513819 1.903 NM_002011
NM_213647
FGFR4

fibroblast growth factor receptor 4

chr7_-_103629962 1.719 NM_005045
NM_173054
RELN

reelin

chr19_+_496453 1.713 NM_130760
NM_130762
MADCAM1

mucosal vascular addressin cell adhesion molecule 1

chr3_-_13008959 1.662 NM_014869
IQSEC1
IQ motif and Sec7 domain 1
chr16_+_69600110 1.659 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr11_+_46403279 1.646 MDK
midkine (neurite growth-promoting factor 2)
chr9_+_71320105 1.625 NM_003558
PIP5K1B
phosphatidylinositol-4-phosphate 5-kinase, type I, beta
chr2_-_174828775 1.622 NM_001017371
SP3
Sp3 transcription factor
chr17_-_42200957 1.621 HDAC5
histone deacetylase 5
chr19_-_41196419 1.617 NM_004756
NUMBL
numb homolog (Drosophila)-like
chr19_-_2702662 1.593 GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr12_-_63328857 1.583 PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr17_-_42201009 1.578 NM_001015053
NM_005474
HDAC5

histone deacetylase 5

chr10_-_95360959 1.573 NM_006744
RBP4
retinol binding protein 4, plasma
chr1_+_155099935 1.572 EFNA1
ephrin-A1
chr20_+_306205 1.568 NM_006943
SOX12
SRY (sex determining region Y)-box 12
chr2_-_61697899 1.544 USP34
ubiquitin specific peptidase 34
chr1_-_21995793 1.535 NM_001145657
NM_002885
RAP1GAP

RAP1 GTPase activating protein

chr2_+_170590241 1.508 NM_144711
KLHL23
kelch-like 23 (Drosophila)
chr17_-_76124767 1.505 TMC6
transmembrane channel-like 6
chr20_-_22564893 1.502 FOXA2
forkhead box A2
chr20_+_34203746 1.454 NM_003116
SPAG4
sperm associated antigen 4
chrX_+_9432980 1.450 NM_005647
TBL1X
transducin (beta)-like 1X-linked
chr11_-_116708334 1.419 NM_000039
APOA1
apolipoprotein A-I
chr19_-_18548118 1.416 NM_001253389
ISYNA1
inositol-3-phosphate synthase 1
chr2_-_174829108 1.414 SP3
Sp3 transcription factor
chr19_-_2702738 1.394 NM_052847
GNG7
guanine nucleotide binding protein (G protein), gamma 7
chr17_-_80606095 1.393 NM_019613
WDR45L
WDR45-like
chr16_+_69599868 1.392 NM_001113178
NM_006599
NM_138713
NM_138714
NM_173214
NM_173215
NFAT5





nuclear factor of activated T-cells 5, tonicity-responsive





chr16_+_69599869 1.387 NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr20_+_35974458 1.381 NM_198291
SRC
v-src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog (avian)
chr6_-_4135701 1.381 NM_001166010
NM_006117
NM_206836
ECI2


enoyl-CoA delta isomerase 2


chr16_+_85645014 1.378 NM_001134473
KIAA0182
KIAA0182
chr19_+_45452427 1.342 APOC2
apolipoprotein C-II
chr1_-_235812994 1.333 NM_001098722
GNG4
guanine nucleotide binding protein (G protein), gamma 4
chr21_-_44496423 1.307 NM_001178008
NM_001178009
CBS

cystathionine-beta-synthase

chr12_-_125348422 1.291 NM_001082959
NM_005505
SCARB1

scavenger receptor class B, member 1

chr11_+_46403205 1.272 NM_002391
MDK
midkine (neurite growth-promoting factor 2)
chr15_+_80445177 1.271 NM_000137
FAH
fumarylacetoacetate hydrolase (fumarylacetoacetase)
chr15_-_45480160 1.268 SHF
Src homology 2 domain containing F
chr8_+_1711869 1.267 NM_018941
CLN8
ceroid-lipofuscinosis, neuronal 8 (epilepsy, progressive with mental retardation)
chr19_+_50016435 1.254 NM_004107
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr2_-_99347430 1.251 MGAT4A
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme A
chr17_-_76124791 1.215 NM_001127198
TMC6
transmembrane channel-like 6
chr11_+_46403302 1.213 NM_001012333
MDK
midkine (neurite growth-promoting factor 2)
chr2_+_47596447 1.212 EPCAM
epithelial cell adhesion molecule
chr12_-_125348346 1.211 SCARB1
scavenger receptor class B, member 1
chr20_+_31350190 1.209 NM_001207055
NM_001207056
NM_006892
NM_175848
NM_175849
DNMT3B




DNA (cytosine-5-)-methyltransferase 3 beta




chr2_+_47596286 1.208 NM_002354
EPCAM
epithelial cell adhesion molecule
chr11_+_46402333 1.204 NM_001012334
MDK
midkine (neurite growth-promoting factor 2)
chr11_-_86666211 1.200 NM_012193
FZD4
frizzled family receptor 4
chr12_-_63328663 1.163 NM_020700
PPM1H
protein phosphatase, Mg2+/Mn2+ dependent, 1H
chr16_-_402617 1.160 NM_003502
NM_181050
AXIN1

axin 1

chr7_-_51384458 1.148 NM_015198
COBL
cordon-bleu homolog (mouse)
chr1_-_15850776 1.145 NM_001229
NM_032996
CASP9

caspase 9, apoptosis-related cysteine peptidase

chr19_+_50016490 1.133 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr16_+_2039945 1.133 NM_004209
SYNGR3
synaptogyrin 3
chr19_+_50016500 1.129 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr15_+_74833517 1.123 NM_006465
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr17_-_65241305 1.123 NM_014877
HELZ
helicase with zinc finger
chr4_+_38665587 1.119 NM_016531
KLF3
Kruppel-like factor 3 (basic)
chr19_+_35532617 1.118 HPN
hepsin
chr2_+_234263153 1.103 DGKD
diacylglycerol kinase, delta 130kDa
chr17_-_65241276 1.093 HELZ
helicase with zinc finger
chr9_-_116139148 1.074 HDHD3
haloacid dehalogenase-like hydrolase domain containing 3
chr2_+_86668428 1.070 KDM3A
lysine (K)-specific demethylase 3A
chrX_-_20285141 1.070 RPS6KA3
ribosomal protein S6 kinase, 90kDa, polypeptide 3
chr7_-_100239136 1.068 NM_003227
TFR2
transferrin receptor 2
chr20_-_62601140 1.067 NM_020713
ZNF512B
zinc finger protein 512B
chr1_+_1981902 1.061 NM_002744
PRKCZ
protein kinase C, zeta
chr19_+_35531409 1.058 NM_002151
NM_182983
HPN

hepsin

chr1_+_212781969 1.055 NM_001040619
NM_001206484
NM_001206488
NM_001674
ATF3



activating transcription factor 3



chr11_-_66234176 1.051 MRPL11
mitochondrial ribosomal protein L11
chr12_-_125348266 1.045 SCARB1
scavenger receptor class B, member 1
chr17_-_36904545 1.038 NM_007144
PCGF2
polycomb group ring finger 2
chr6_+_7107986 1.037 NM_001003698
NM_001003699
NM_001003700
RREB1


ras responsive element binding protein 1


chrX_+_152990322 1.025 NM_000033
ABCD1
ATP-binding cassette, sub-family D (ALD), member 1
chr3_+_50304989 1.021 NM_001005914
NM_004636
SEMA3B

sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B

chr2_-_11484699 1.018 NM_004850
ROCK2
Rho-associated, coiled-coil containing protein kinase 2
chr17_+_37896219 1.014 NM_001242443
GRB7
growth factor receptor-bound protein 7
chr14_-_38064440 1.007 NM_004496
FOXA1
forkhead box A1
chr4_+_1795004 0.997 NM_000142
NM_001163213
NM_022965
FGFR3


fibroblast growth factor receptor 3


chr8_+_86089618 0.997 NM_001083588
NM_001951
E2F5

E2F transcription factor 5, p130-binding

chr19_-_18717467 0.991 CRLF1
cytokine receptor-like factor 1
chr20_+_30946786 0.980 ASXL1
additional sex combs like 1 (Drosophila)
chr17_-_41622727 0.973 ETV4
ets variant 4
chr1_+_214161279 0.971 PROX1
prospero homeobox 1
chr2_+_54683276 0.967 NM_003128
SPTBN1
spectrin, beta, non-erythrocytic 1
chr17_+_48503607 0.967 ACSF2
acyl-CoA synthetase family member 2
chr2_+_8822112 0.967 NM_002166
ID2
inhibitor of DNA binding 2, dominant negative helix-loop-helix protein
chr2_-_200322699 0.964 NM_001172509
SATB2
SATB homeobox 2
chr22_+_21771661 0.960 NM_015094
HIC2
hypermethylated in cancer 2
chr10_-_28821459 0.954 LOC220906
uncharacterized LOC220906
chr17_+_79935493 0.953 ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr17_+_48503518 0.952 NM_025149
ACSF2
acyl-CoA synthetase family member 2
chr17_+_79935410 0.952 NM_001251888
NM_024083
ASPSCR1

alveolar soft part sarcoma chromosome region, candidate 1

chr20_+_31350387 0.950 DNMT3B
DNA (cytosine-5-)-methyltransferase 3 beta
chr17_+_76164624 0.949 NM_004710
SYNGR2
synaptogyrin 2
chrX_+_46937807 0.946 RGN
regucalcin (senescence marker protein-30)
chrX_+_46937889 0.941 RGN
regucalcin (senescence marker protein-30)
chr19_-_9929682 0.938 NM_017703
FBXL12
F-box and leucine-rich repeat protein 12
chr1_+_212782103 0.926 ATF3
activating transcription factor 3
chr1_-_11714396 0.923 FBXO2
F-box protein 2
chr12_+_3068442 0.921 NM_003213
NM_201441
NM_201443
TEAD4


TEA domain family member 4


chrX_+_46937744 0.921 NM_004683
NM_152869
RGN

regucalcin (senescence marker protein-30)

chr19_+_35532640 0.916 HPN
hepsin
chr19_+_45349584 0.915 PVRL2
poliovirus receptor-related 2 (herpesvirus entry mediator B)
chr19_-_47734215 0.914 NM_014417
BBC3
BCL2 binding component 3
chr9_+_138371627 0.914 NM_014811
PPP1R26
protein phosphatase 1, regulatory subunit 26
chr8_-_80679897 0.913 NM_001040708
NM_012258
HEY1

hairy/enhancer-of-split related with YRPW motif 1

chr2_+_234263141 0.911 NM_152879
DGKD
diacylglycerol kinase, delta 130kDa
chr2_-_61697846 0.907 NM_014709
USP34
ubiquitin specific peptidase 34
chr2_-_27435014 0.901 NM_021095
SLC5A6
solute carrier family 5 (sodium-dependent vitamin transporter), member 6
chr19_-_55866063 0.900 NM_144613
COX6B2
cytochrome c oxidase subunit VIb polypeptide 2 (testis)
chr17_-_56591900 0.900 MTMR4
myotubularin related protein 4
chr2_+_86668488 0.900 NM_001146688
KDM3A
lysine (K)-specific demethylase 3A
chr16_-_89768094 0.900 NM_152339
SPATA2L
spermatogenesis associated 2-like
chr11_-_75236866 0.894 GDPD5
glycerophosphodiester phosphodiesterase domain containing 5
chr7_+_94285736 0.892 PEG10
paternally expressed 10
chr10_+_102729249 0.890 SEMA4G
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr4_-_1166364 0.886 SPON2
spondin 2, extracellular matrix protein
chr7_-_22396511 0.885 NM_012294
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr16_+_29817810 0.884 NM_001042539
NM_002383
MAZ

MYC-associated zinc finger protein (purine-binding transcription factor)

chr14_+_21538339 0.874 NM_018071
ARHGEF40
Rho guanine nucleotide exchange factor (GEF) 40
chr7_+_94285676 0.871 NM_001172437
NM_001172438
PEG10

paternally expressed 10

chr1_-_11714738 0.870 NM_012168
FBXO2
F-box protein 2
chr4_-_1166378 0.869 SPON2
spondin 2, extracellular matrix protein
chr10_+_111985628 0.865 NM_005962
MXI1
MAX interactor 1
chr1_+_11333244 0.864 NM_013319
UBIAD1
UbiA prenyltransferase domain containing 1
chr2_+_85198431 0.861 KCMF1
potassium channel modulatory factor 1
chr12_+_57522247 0.860 NM_002332
LRP1
low density lipoprotein receptor-related protein 1
chr12_+_112204711 0.860 ALDH2
aldehyde dehydrogenase 2 family (mitochondrial)
chr16_-_402398 0.857 AXIN1
axin 1
chr2_+_219264719 0.856 CTDSP1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr7_+_138145179 0.855 TRIM24
tripartite motif containing 24
chr7_+_116164838 0.853 NM_001753
CAV1
caveolin 1, caveolae protein, 22kDa
chr11_+_114166534 0.853 NM_006169
NNMT
nicotinamide N-methyltransferase
chr2_+_86668270 0.850 NM_018433
KDM3A
lysine (K)-specific demethylase 3A
chr3_+_73046081 0.849 NM_174907
PPP4R2
protein phosphatase 4, regulatory subunit 2
chr6_+_42981955 0.848 KLHDC3
kelch domain containing 3
chr9_-_36401149 0.848 NM_194330
RNF38
ring finger protein 38
chr14_-_21566497 0.845 ZNF219
zinc finger protein 219
chr22_-_19165872 0.845 SLC25A1
solute carrier family 25 (mitochondrial carrier; citrate transporter), member 1
chr19_+_50016606 0.845 FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr19_+_56652689 0.843 ZNF444
zinc finger protein 444
chr19_+_14544216 0.843 PKN1
protein kinase N1
chr7_+_65338161 0.841 NM_173517
VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr19_-_39342957 0.841 NM_001005335
HNRNPL
heterogeneous nuclear ribonucleoprotein L
chr9_-_36400817 0.840 NM_194328
NM_194332
RNF38

ring finger protein 38

chr16_-_90085786 0.838 NM_001042610
DBNDD1
dysbindin (dystrobrevin binding protein 1) domain containing 1
chr16_+_2587989 0.838 PDPK1
3-phosphoinositide dependent protein kinase-1
chr7_+_73868397 0.837 GTF2IRD1
GTF2I repeat domain containing 1
chr16_+_29690328 0.835 NM_014298
QPRT
quinolinate phosphoribosyltransferase
chr1_-_11714471 0.832 FBXO2
F-box protein 2
chr20_+_34680569 0.831 EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr2_+_27309610 0.828 NM_000221
NM_006488
KHK

ketohexokinase (fructokinase)

chr6_+_42981975 0.827 KLHDC3
kelch domain containing 3
chr17_-_53499055 0.827 NM_012329
MMD
monocyte to macrophage differentiation-associated
chr21_+_47649066 0.826 MCM3AP-AS1
MCM3AP antisense RNA 1 (non-protein coding)
chr2_-_176032850 0.826 NM_001880
ATF2
activating transcription factor 2
chr11_+_46403260 0.824 MDK
midkine (neurite growth-promoting factor 2)
chr6_+_42982013 0.816 KLHDC3
kelch domain containing 3
chr16_+_68119211 0.816 NM_004555
NM_173163
NM_173165
NFATC3


nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3


chr19_-_18548788 0.814 NM_001170939
ISYNA1
inositol-3-phosphate synthase 1
chr4_-_57301643 0.812 NM_002703
PPAT
phosphoribosyl pyrophosphate amidotransferase
chr20_+_34742656 0.811 NM_012156
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr2_-_20212448 0.811 NM_002381
MATN3
matrilin 3
chr8_-_37756971 0.810 NM_001002814
NM_025151
RAB11FIP1

RAB11 family interacting protein 1 (class I)

chr6_-_99395774 0.809 FBXL4
F-box and leucine-rich repeat protein 4
chr15_-_60884615 0.807 NM_134262
RORA
RAR-related orphan receptor A
chr6_+_42981840 0.802 NM_057161
KLHDC3
kelch domain containing 3
chr1_-_21978287 0.801 NM_001145658
RAP1GAP
RAP1 GTPase activating protein
chr19_+_925984 0.796 NM_005224
ARID3A
AT rich interactive domain 3A (BRIGHT-like)
chr4_+_6271605 0.796 WFS1
Wolfram syndrome 1 (wolframin)
chr16_+_68119350 0.795 NFATC3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr5_+_92920592 0.788 NR2F1
NR2F2
nuclear receptor subfamily 2, group F, member 1
nuclear receptor subfamily 2, group F, member 2
chr4_-_1166547 0.787 NM_012445
SPON2
spondin 2, extracellular matrix protein
chr16_-_8962842 0.787 NM_014316
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr2_-_172016904 0.785 TLK1
tousled-like kinase 1
chr9_-_132805456 0.784 NM_015033
FNBP1
formin binding protein 1
chr11_-_2159472 0.777 IGF2
insulin-like growth factor 2 (somatomedin A)
chr1_-_36023005 0.776 NM_024874
KIAA0319L
KIAA0319-like
chr3_+_38495778 0.776 NM_001106
ACVR2B
activin A receptor, type IIB
chr22_-_31742217 0.773 NM_014323
NM_032050
NM_032051
NM_032052
PATZ1



POZ (BTB) and AT hook containing zinc finger 1



chr21_-_44495894 0.772 NM_000071
CBS
cystathionine-beta-synthase
chr19_+_708766 0.771 NM_001040134
NM_002579
PALM

paralemmin

chr17_-_41623246 0.771 NM_001986
ETV4
ets variant 4
chr2_-_39347562 0.769 NM_005633
SOS1
son of sevenless homolog 1 (Drosophila)
chr18_-_25756946 0.767 CDH2
cadherin 2, type 1, N-cadherin (neuronal)

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
93.01 1.82e-03 GO:0034384 high-density lipoprotein particle clearance
9.95 3.76e-03 GO:0006869 lipid transport
3.04 4.40e-03 GO:0065009 regulation of molecular function
9.12 6.70e-03 GO:0010876 lipid localization
1.82 1.25e-02 GO:0032501 multicellular organismal process
186.01 1.78e-02 GO:0035376 sterol import
186.01 1.78e-02 GO:0035382 sterol transmembrane transport
186.01 1.78e-02 GO:0070508 cholesterol import
4.07 1.90e-02 GO:0030182 neuron differentiation
3.63 2.74e-02 GO:0044093 positive regulation of molecular function
3.59 3.15e-02 GO:0048699 generation of neurons
2.16 4.56e-02 GO:0048518 positive regulation of biological process

Nothing significant found in compartment category.

Nothing significant found in function category.