Motif ID: ZBTB16.p2

Z-value: 2.667


Transcription factors associated with ZBTB16.p2:

Gene SymbolEntrez IDGene Name
ZBTB16 7704 zinc finger and BTB domain containing 16

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ZBTB16chr11_+_113931228,
chr11_+_113930430,
chr11_+_113930296
0.009.9e-01Click!


Activity profile for motif ZBTB16.p2.

activity profile for motif ZBTB16.p2


Sorted Z-values histogram for motif ZBTB16.p2

Sorted Z-values for motif ZBTB16.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ZBTB16.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_198608136 6.154 NM_002838
NM_080921
NM_080923
PTPRC


protein tyrosine phosphatase, receptor type, C


chr12_-_53601051 5.972 ITGB7
integrin, beta 7
chr7_+_26400503 5.775 NM_001199837
SNX10
sorting nexin 10
chr1_+_198608216 5.129 PTPRC
protein tyrosine phosphatase, receptor type, C
chr12_-_53600999 4.712 NM_000889
ITGB7
integrin, beta 7
chr1_+_198608244 4.168 PTPRC
protein tyrosine phosphatase, receptor type, C
chr13_-_99959649 3.777 NM_004951
GPR183
G protein-coupled receptor 183
chr19_-_48759141 3.499 NM_001184902
NM_001184904
CARD8

caspase recruitment domain family, member 8

chr13_-_46756291 3.358 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr2_-_89292396 3.355 IGKC
immunoglobulin kappa constant
chr13_-_99910548 3.340 NM_001098200
NM_005292
GPR18

G protein-coupled receptor 18

chr19_-_48752921 3.324 NM_001184901
NM_001184903
NM_014959
CARD8


caspase recruitment domain family, member 8


chr16_+_81812899 2.879 PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr16_+_81812897 2.848 NM_002661
PLCG2
phospholipase C, gamma 2 (phosphatidylinositol-specific)
chr22_+_23229959 2.823 NM_001178126
IGLL5
IGLC1
immunoglobulin lambda-like polypeptide 5
immunoglobulin lambda constant 1 (Mcg marker)
chr6_+_12717036 2.735 NM_001242648
NM_030948
PHACTR1

phosphatase and actin regulator 1

chr3_-_15382874 2.582 NM_001018009
SH3BP5
SH3-domain binding protein 5 (BTK-associated)
chr8_-_80993009 2.373 NM_001025252
TPD52
tumor protein D52
chr2_+_33661392 2.364 NM_170672
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr1_+_174844655 2.352 NM_001035230
RABGAP1L
RAB GTPase activating protein 1-like
chrX_-_78623006 2.330 NM_001171581
NM_004867
ITM2A

integral membrane protein 2A

chr12_+_54892567 2.279 NM_001184976
NCKAP1L
NCK-associated protein 1-like
chr11_+_67351276 2.270 GSTP1
glutathione S-transferase pi 1
chr10_+_35426709 2.177 NM_183011
NM_183012
CREM

cAMP responsive element modulator

chr4_+_15779887 2.152 NM_001775
CD38
CD38 molecule
chr12_+_25205488 2.125 LRMP
lymphoid-restricted membrane protein
chr1_-_111743297 2.081 DENND2D
DENN/MADD domain containing 2D
chr6_-_44233244 2.064 NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr22_+_22723972 1.989


chr15_-_55562483 1.979 NM_183234
NM_004580
RAB27A

RAB27A, member RAS oncogene family

chr19_-_20607761 1.959 ZNF826P
zinc finger protein 826, pseudogene
chr6_-_33041266 1.930 NM_033554
HLA-DPA1
major histocompatibility complex, class II, DP alpha 1
chrX_+_12885190 1.891 NM_016562
TLR7
toll-like receptor 7
chr14_-_106471439 1.880 IGHA1
IGHG1
IGHM
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr14_-_106610338 1.857 IGHV4-31
IGHG1
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant gamma 1 (G1m marker)
chr21_+_42797977 1.844 NM_002462
NM_001178046
MX1

myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)

chr8_+_86099909 1.837 NM_001083589
E2F5
E2F transcription factor 5, p130-binding
chr10_-_11574273 1.827 NM_001080491
USP6NL
USP6 N-terminal like
chr18_-_47814691 1.815 NM_001101654
NM_014593
CXXC1

CXXC finger protein 1

chr7_+_26331611 1.784 SNX10
sorting nexin 10
chr5_-_94224601 1.770 MCTP1
multiple C2 domains, transmembrane 1
chr6_-_44233499 1.739 NM_004556
NFKBIE
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr10_+_97515408 1.700 NM_001164178
NM_001164181
NM_001164179
NM_001164182
NM_001164183
NM_001776
ENTPD1





ectonucleoside triphosphate diphosphohydrolase 1





chr4_-_84035908 1.695 NM_001130715
NM_016619
PLAC8

placenta-specific 8

chr14_+_88471467 1.687 NM_003608
GPR65
G protein-coupled receptor 65
chr3_-_124930192 1.670 NM_001195483
SLC12A8
solute carrier family 12 (potassium/chloride transporters), member 8
chr1_+_111770280 1.665 NM_001025197
NM_004000
CHI3L2

chitinase 3-like 2

chr10_+_62538088 1.656 NM_001170406
NM_001170407
NM_001786
NM_033379
CDK1



cyclin-dependent kinase 1



chr4_-_84035888 1.645 PLAC8
placenta-specific 8
chr14_-_106725620 1.638 IGHV4-31
IGHV3-23
IGHA1
IGHG1
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy variable 3-23
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant mu
chr6_+_14117486 1.561 NM_001251901
CD83
CD83 molecule
chr4_+_106631966 1.530 NM_001031720
GSTCD
glutathione S-transferase, C-terminal domain containing
chr21_-_15918635 1.527 NM_022136
SAMSN1
SAM domain, SH3 domain and nuclear localization signals 1
chr10_+_70847817 1.497 NM_002727
SRGN
serglycin
chr8_-_102803438 1.492 NM_032041
NCALD
neurocalcin delta
chr1_+_100326765 1.446 NM_000645
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr3_+_121774208 1.444 NM_001206924
NM_001206925
NM_175862
CD86


CD86 molecule


chr19_-_39826676 1.443 NM_004877
GMFG
glia maturation factor, gamma
chr12_+_14538232 1.413 ATF7IP
activating transcription factor 7 interacting protein
chr12_-_57146081 1.411 NM_000946
PRIM1
primase, DNA, polypeptide 1 (49kDa)
chr14_-_106691698 1.396


chr13_-_41556360 1.378 NM_001145353
ELF1
E74-like factor 1 (ets domain transcription factor)
chr10_-_99052429 1.373 NM_001204300
NM_032900
ARHGAP19

Rho GTPase activating protein 19

chr6_+_27777713 1.369 NM_003536
HIST1H3H
histone cluster 1, H3h
chr19_-_20844312 1.358 NM_001076675
NM_145297
ZNF626

zinc finger protein 626

chr2_-_38303265 1.342 CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr11_-_67450536 1.329 RPL37
ribosomal protein L37
chr4_+_40198526 1.324 NM_004310
RHOH
ras homolog gene family, member H
chr8_+_104831415 1.319 NM_014677
RIMS2
regulating synaptic membrane exocytosis 2
chr7_-_124570036 1.297 NM_001042594
NM_015450
POT1

protection of telomeres 1 homolog (S. pombe)

chr1_+_241695433 1.291 NM_003679
KMO
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr2_-_38303307 1.290 NM_000104
CYP1B1
cytochrome P450, family 1, subfamily B, polypeptide 1
chr20_-_52199635 1.289 NM_006526
ZNF217
zinc finger protein 217
chr13_-_41593405 1.270 ELF1
E74-like factor 1 (ets domain transcription factor)
chr16_+_20775311 1.242 NM_005622
NM_202000
ACSM3

acyl-CoA synthetase medium-chain family member 3

chr12_+_118454505 1.218 NM_001130112
NM_001206801
NM_007370
NM_181578
RFC5



replication factor C (activator 1) 5, 36.5kDa



chr19_+_20277991 1.216 NM_052852
ZNF486
zinc finger protein 486
chr14_-_106478129 1.212 IGHV4-31
IGHD
IGHG3
IGHM
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 3 (G3m marker)
immunoglobulin heavy constant mu
chr17_+_67498391 1.204 MAP2K6
mitogen-activated protein kinase kinase 6
chr7_+_26331493 1.187 NM_001199835
NM_013322
SNX10

sorting nexin 10

chr11_+_67351065 1.183 NM_000852
GSTP1
glutathione S-transferase pi 1
chr5_+_68667280 1.177 NM_133339
RAD17
RAD17 homolog (S. pombe)
chr17_-_29648631 1.169 NM_001003927
NM_014210
EVI2A

ecotropic viral integration site 2A

chr16_-_85722503 1.168 GINS2
GINS complex subunit 2 (Psf2 homolog)
chr10_-_99052391 1.167 ARHGAP19-SLIT1
ARHGAP19
ARHGAP19-SLIT1 readthrough
Rho GTPase activating protein 19
chr7_+_116660263 1.151 ST7
suppression of tumorigenicity 7
chr4_-_76957139 1.132 NM_005409
CXCL11
chemokine (C-X-C motif) ligand 11
chr3_+_136649316 1.122 NM_001190796
NCK1
NCK adaptor protein 1
chrX_+_48542159 1.120 NM_000377
WAS
Wiskott-Aldrich syndrome (eczema-thrombocytopenia)
chr3_+_98250742 1.116 NM_005290
GPR15
G protein-coupled receptor 15
chr1_-_150738255 1.114 CTSS
cathepsin S
chr1_+_160709038 1.106 NM_021181
SLAMF7
SLAM family member 7
chr5_-_94417544 1.094 NM_001002796
MCTP1
multiple C2 domains, transmembrane 1
chr5_-_88199868 1.090 NM_001131005
NM_001193347
MEF2C

myocyte enhancer factor 2C

chr7_+_116660291 1.086 ST7
suppression of tumorigenicity 7
chr2_-_89619820 1.083 IGKC
immunoglobulin kappa constant
chr1_+_100316530 1.082 NM_000646
AGL
amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
chr13_-_41556188 1.051 ELF1
E74-like factor 1 (ets domain transcription factor)
chr13_-_41593491 1.024 NM_172373
ELF1
E74-like factor 1 (ets domain transcription factor)
chr16_-_85722587 1.021 NM_016095
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr10_+_70847857 1.014 SRGN
serglycin
chr7_+_150264457 0.974 NM_018326
GIMAP4
GTPase, IMAP family member 4
chr15_-_58306185 0.973 NM_170697
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr5_+_102465256 0.960 NM_015216
PPIP5K2
diphosphoinositol pentakisphosphate kinase 2
chr5_+_67586466 0.955 NM_181504
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chr7_+_7606634 0.953 MIOS
missing oocyte, meiosis regulator, homolog (Drosophila)
chr17_-_18266691 0.943 NM_004169
NM_148918
SHMT1

serine hydroxymethyltransferase 1 (soluble)

chr7_+_7606549 0.942 NM_019005
MIOS
missing oocyte, meiosis regulator, homolog (Drosophila)
chr15_+_81489218 0.931 NM_001172128
IL16
interleukin 16
chr3_-_189838673 0.921 LEPREL1
leprecan-like 1
chr5_+_49961732 0.919 NM_001178055
PARP8
poly (ADP-ribose) polymerase family, member 8
chr6_-_154651214 0.919 NM_001130699
IPCEF1
interaction protein for cytohesin exchange factors 1
chr8_-_30585442 0.912 NM_000637
NM_001195102
NM_001195103
NM_001195104
GSR



glutathione reductase



chr6_+_32605182 0.905 NM_002122
HLA-DQA1
major histocompatibility complex, class II, DQ alpha 1
chr13_-_46756326 0.901 NM_002298
LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_-_51887740 0.899 NM_001159969
EPS15
epidermal growth factor receptor pathway substrate 15
chr18_+_29671817 0.892 NM_016271
RNF138
ring finger protein 138
chr2_+_172821874 0.889 HAT1
histone acetyltransferase 1
chr3_+_122044010 0.889 NM_005213
CSTA
cystatin A (stefin A)
chr10_-_27057776 0.882 ABI1
abl-interactor 1
chr19_-_20748540 0.880 NM_001159293
ZNF737
zinc finger protein 737
chr14_+_39649711 0.875 PNN
pinin, desmosome associated protein
chr3_+_39509069 0.870 NM_182935
MOBP
myelin-associated oligodendrocyte basic protein
chr14_+_70236266 0.852 SRSF5
serine/arginine-rich splicing factor 5
chr5_+_70944968 0.851 MCCC2
methylcrotonoyl-CoA carboxylase 2 (beta)
chr13_-_46756295 0.850 LCP1
lymphocyte cytosolic protein 1 (L-plastin)
chr1_+_186798031 0.847 NM_024420
PLA2G4A
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr1_+_167298382 0.842 POU2F1
POU class 2 homeobox 1
chr6_+_134274247 0.841 NM_004865
TBPL1
TBP-like 1
chr7_-_104909442 0.834 NM_182691
SRPK2
SRSF protein kinase 2
chr17_-_41739261 0.828 NM_001040002
MEOX1
mesenchyme homeobox 1
chr15_-_93277303 0.826 FAM174B
family with sequence similarity 174, member B
chr22_+_23054862 0.815 IGLV3-21
IGLJ3
IGLC1
immunoglobulin lambda variable 3-21
immunoglobulin lambda joining 3
immunoglobulin lambda constant 1 (Mcg marker)
chr16_-_21314371 0.805 NM_001014444
NM_001888
CRYM

crystallin, mu

chrX_-_23925947 0.799 NM_024122
APOO
apolipoprotein O
chr18_-_51690988 0.795 MBD2
methyl-CpG binding domain protein 2
chr7_+_39017608 0.785 NM_001166018
NM_007252
POU6F2

POU class 6 homeobox 2

chr3_-_47098906 0.785 SETD2
SET domain containing 2
chr22_-_42336222 0.783 NM_001110215
CENPM
centromere protein M
chr11_+_5641173 0.783 NM_001003827
TRIM34
tripartite motif containing 34
chr7_+_28725597 0.780 NM_001011666
CREB5
cAMP responsive element binding protein 5
chr6_+_10521564 0.777 NM_145649
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr10_-_65028825 0.776 NM_004241
JMJD1C
jumonji domain containing 1C
chr14_-_20797532 0.775 NM_182852
NM_182851
CCNB1IP1

cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

chr3_-_137893718 0.762 DBR1
debranching enzyme homolog 1 (S. cerevisiae)
chr6_+_4890225 0.755 NM_001143971
CDYL
chromodomain protein, Y-like
chr14_+_58906398 0.747 NM_001244193
KIAA0586
KIAA0586
chr3_-_33700932 0.741 NM_001207044
CLASP2
cytoplasmic linker associated protein 2
chr7_-_64023331 0.729 ZNF680
zinc finger protein 680
chr3_-_197300193 0.716 NM_203315
BDH1
3-hydroxybutyrate dehydrogenase, type 1
chr5_+_159656436 0.712 NM_001445
FABP6
fatty acid binding protein 6, ileal
chr5_-_176836488 0.710 F12
coagulation factor XII (Hageman factor)
chr17_-_18177716 0.701 TOP3A
topoisomerase (DNA) III alpha
chr5_-_88119604 0.699 NM_001193348
NM_001193349
MEF2C

myocyte enhancer factor 2C

chr13_-_41837619 0.692 NM_004294
MTRF1
mitochondrial translational release factor 1
chr6_+_26251826 0.686 NM_003524
HIST1H2BH
histone cluster 1, H2bh
chr3_-_186857188 0.678 NM_052969
RPL39L
ribosomal protein L39-like
chr3_-_185641596 0.670 TRA2B
transformer 2 beta homolog (Drosophila)
chr5_-_176836535 0.667 NM_000505
F12
coagulation factor XII (Hageman factor)
chr3_-_164796275 0.659 NM_001041
SI
sucrase-isomaltase (alpha-glucosidase)
chr2_+_204801453 0.658 NM_012092
ICOS
inducible T-cell co-stimulator
chr6_-_29527477 0.657 UBD
ubiquitin D
chr3_+_112051914 0.654 NM_001004196
NM_005944
CD200

CD200 molecule

chr3_-_141747434 0.654 NM_001178141
NM_001178142
NM_006286
TFDP2


transcription factor Dp-2 (E2F dimerization partner 2)


chr2_+_216176678 0.653 NM_004044
ATIC
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr2_-_20512016 0.652 PUM2
pumilio homolog 2 (Drosophila)
chr1_-_169703178 0.649 NM_000450
SELE
selectin E
chr14_-_45722332 0.648 MIS18BP1
MIS18 binding protein 1
chr15_-_60919642 0.644 NM_002943
NM_134260
RORA

RAR-related orphan receptor A

chrX_-_73834460 0.643 NM_016120
NM_183353
RLIM

ring finger protein, LIM domain interacting

chr7_-_64023454 0.642 NM_001130022
NM_178558
ZNF680

zinc finger protein 680

chr4_+_74347461 0.637 NM_001133
AFM
afamin
chr17_-_40833840 0.637 NM_016602
CCR10
chemokine (C-C motif) receptor 10
chr15_+_66585632 0.629 NM_133375
DIS3L
DIS3 mitotic control homolog (S. cerevisiae)-like
chrX_+_118602362 0.629 NM_001152
SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr6_+_26104103 0.628 NM_003542
HIST2H4B
HIST1H4C
histone cluster 2, H4b
histone cluster 1, H4c
chr1_-_169680677 0.627 NM_000655
SELL
selectin L
chr5_+_67588395 0.622 NM_001242466
PIK3R1
phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
chrX_+_118602391 0.621 SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr4_+_54292035 0.617 FIP1L1
FIP1 like 1 (S. cerevisiae)
chr10_-_6019880 0.617 NM_001243539
IL15RA
interleukin 15 receptor, alpha
chr17_+_18768781 0.617 NM_001243940
PRPSAP2
phosphoribosyl pyrophosphate synthetase-associated protein 2
chr12_+_9822205 0.616 NM_001197318
NM_013269
NM_001004419
NM_001197317
NM_001197319
CLEC2D




C-type lectin domain family 2, member D




chr5_+_159614373 0.613 NM_001130958
FABP6
fatty acid binding protein 6, ileal
chr17_-_3599298 0.610 P2RX5
purinergic receptor P2X, ligand-gated ion channel, 5
chr5_+_159848876 0.603 PTTG1
pituitary tumor-transforming 1
chr2_-_73520448 0.600 NM_001965
EGR4
early growth response 4
chr13_-_47012324 0.600 KIAA0226L
KIAA0226-like
chr10_-_94257470 0.596 NM_001165946
IDE
insulin-degrading enzyme
chr10_+_35484054 0.595 NM_182717
NM_182718
NM_182719
NM_182720
CREM



cAMP responsive element modulator



chr19_-_50666279 0.591 NM_152358
IZUMO2
IZUMO family member 2
chr3_-_137893745 0.591 NM_016216
DBR1
debranching enzyme homolog 1 (S. cerevisiae)
chr7_-_107770785 0.584 NM_007356
LAMB4
laminin, beta 4
chr14_-_106692107 0.584 IGHV4-31
IGHA1
IGHD
IGHG1
IGHG3
immunoglobulin heavy variable 4-31
immunoglobulin heavy constant alpha 1
immunoglobulin heavy constant delta
immunoglobulin heavy constant gamma 1 (G1m marker)
immunoglobulin heavy constant gamma 3 (G3m marker)
chr12_+_12938540 0.583 NM_030817
APOLD1
apolipoprotein L domain containing 1
chr3_-_56809594 0.578 NM_001128616
ARHGEF3
Rho guanine nucleotide exchange factor (GEF) 3
chr10_+_111765725 0.577 NM_019903
ADD3
adducin 3 (gamma)
chr7_+_106505876 0.570 NM_002649
PIK3CG
phosphoinositide-3-kinase, catalytic, gamma polypeptide
chr6_-_123957941 0.569 NM_001251987
NM_006073
TRDN

triadin

chr1_-_217113007 0.568 NM_001243512
NM_001243513
NM_001243510
NM_001243511
ESRRG



estrogen-related receptor gamma




Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
4.79 1.29e-11 GO:0002376 immune system process
5.99 2.42e-10 GO:0006955 immune response
11.00 1.41e-08 GO:0002253 activation of immune response
11.73 2.03e-07 GO:0002757 immune response-activating signal transduction
11.52 2.51e-07 GO:0002764 immune response-regulating signaling pathway
11.38 2.88e-07 GO:0046649 lymphocyte activation
9.88 2.98e-07 GO:0045321 leukocyte activation
8.70 3.20e-07 GO:0050778 positive regulation of immune response
6.70 7.56e-07 GO:0002684 positive regulation of immune system process
6.61 9.12e-07 GO:0050776 regulation of immune response
5.19 1.25e-06 GO:0002682 regulation of immune system process
12.42 3.85e-06 GO:0002252 immune effector process
14.24 4.74e-05 GO:0050851 antigen receptor-mediated signaling pathway
13.08 9.24e-05 GO:0002429 immune response-activating cell surface receptor signaling pathway
12.69 1.17e-04 GO:0002768 immune response-regulating cell surface receptor signaling pathway
5.32 1.63e-04 GO:0001775 cell activation
2.71 1.04e-03 GO:0048583 regulation of response to stimulus
7.48 1.74e-03 GO:0051249 regulation of lymphocyte activation
37.68 1.84e-03 GO:0050853 B cell receptor signaling pathway
8.33 2.90e-03 GO:0051251 positive regulation of lymphocyte activation
10.20 3.10e-03 GO:0042110 T cell activation
19.07 3.45e-03 GO:0002263 cell activation involved in immune response
19.07 3.45e-03 GO:0002366 leukocyte activation involved in immune response
6.81 3.75e-03 GO:0002694 regulation of leukocyte activation
7.78 4.82e-03 GO:0002696 positive regulation of leukocyte activation
6.53 5.25e-03 GO:0050865 regulation of cell activation
7.64 5.51e-03 GO:0050867 positive regulation of cell activation
25.63 9.44e-03 GO:0030890 positive regulation of B cell proliferation
24.64 1.11e-02 GO:0002285 lymphocyte activation involved in immune response
5.08 1.46e-02 GO:0045087 innate immune response
48.04 1.60e-02 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB cascade
10.02 1.68e-02 GO:0070663 regulation of leukocyte proliferation
12.72 2.58e-02 GO:0002449 lymphocyte mediated immunity
3.41 2.88e-02 GO:0006952 defense response
40.04 2.91e-02 GO:0043372 positive regulation of CD4-positive, alpha-beta T cell differentiation
40.04 2.91e-02 GO:2000516 positive regulation of CD4-positive, alpha-beta T cell activation
12.33 3.00e-02 GO:0042113 B cell activation
3.38 3.13e-02 GO:0048584 positive regulation of response to stimulus
18.85 3.32e-02 GO:0030888 regulation of B cell proliferation
11.96 3.47e-02 GO:0050671 positive regulation of lymphocyte proliferation
11.78 3.73e-02 GO:0032946 positive regulation of mononuclear cell proliferation
11.61 4.00e-02 GO:0070665 positive regulation of leukocyte proliferation

Nothing significant found in compartment category.

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
28.03 4.47e-07 GO:0003823 antigen binding
3.07 1.52e-02 GO:0030234 enzyme regulator activity
28.27 1.53e-02 GO:0001608 nucleotide receptor activity, G-protein coupled
28.27 1.53e-02 GO:0045028 purinergic nucleotide receptor activity, G-protein coupled
9.21 2.10e-02 GO:0019207 kinase regulator activity
20.03 4.42e-02 GO:0001614 purinergic nucleotide receptor activity
20.03 4.42e-02 GO:0016502 nucleotide receptor activity