Motif ID: AGCACCA

Z-value: 0.781


Mature miRNA associated with seed AGCACCA:

NamemiRBase Accession
hsa-miR-29a-3p MIMAT0000086
hsa-miR-29b-3p MIMAT0000100
hsa-miR-29c-3p MIMAT0000681



Activity profile for motif AGCACCA.

activity profile for motif AGCACCA


Sorted Z-values histogram for motif AGCACCA

Sorted Z-values for motif AGCACCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCACCA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_23261589 1.843 ENST00000524168.1
ENST00000523833.2
ENST00000519243.1
ENST00000389131.3
LOXL2



lysyl oxidase-like 2



chr2_-_1748214 1.740 ENST00000433670.1
ENST00000425171.1
ENST00000252804.4
PXDN


peroxidasin homolog (Drosophila)


chr1_-_17304771 1.732 ENST00000375534.3
MFAP2
microfibrillar-associated protein 2
chrX_-_107681633 1.392 ENST00000394872.2
ENST00000334504.7
COL4A6

collagen, type IV, alpha 6

chr1_+_151030234 1.316 ENST00000368921.3
MLLT11
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 11
chr16_+_55512742 1.260 ENST00000568715.1
ENST00000219070.4
MMP2

matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

chr13_+_110959598 1.160 ENST00000360467.5
COL4A2
collagen, type IV, alpha 2
chr20_-_43280361 1.152 ENST00000372874.4
ADA
adenosine deaminase
chr3_-_48632593 1.125 ENST00000454817.1
ENST00000328333.8
COL7A1

collagen, type VII, alpha 1

chr17_-_48278983 1.069 ENST00000225964.5
COL1A1
collagen, type I, alpha 1
chr1_-_113498943 0.956 ENST00000369626.3
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr2_-_230933709 0.883 ENST00000436869.1
ENST00000295190.4
SLC16A14

solute carrier family 16, member 14

chr2_-_190044480 0.880 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr15_+_81071684 0.852 ENST00000220244.3
ENST00000394685.3
ENST00000356249.5
KIAA1199


KIAA1199


chr20_-_5591626 0.809 ENST00000379019.4
GPCPD1
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr19_+_48216600 0.767 ENST00000263277.3
ENST00000538399.1
EHD2

EH-domain containing 2

chr7_+_130126012 0.746 ENST00000341441.5
MEST
mesoderm specific transcript
chr7_+_100797678 0.746 ENST00000337619.5
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr9_-_110251836 0.719 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr7_-_143059845 0.710 ENST00000443739.2
FAM131B
family with sequence similarity 131, member B
chr17_-_8055747 0.701 ENST00000317276.4
ENST00000581703.1
PER1

period circadian clock 1

chr1_+_182992545 0.691 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr12_-_67072714 0.674 ENST00000545666.1
ENST00000398016.3
ENST00000359742.4
ENST00000286445.7
ENST00000538211.1
GRIP1




glutamate receptor interacting protein 1




chr2_-_238323007 0.662 ENST00000295550.4
COL6A3
collagen, type VI, alpha 3
chr5_-_139726181 0.646 ENST00000507104.1
ENST00000230990.6
HBEGF

heparin-binding EGF-like growth factor

chr11_+_842808 0.623 ENST00000397397.2
ENST00000397411.2
ENST00000397396.1
TSPAN4


tetraspanin 4


chr7_-_128049955 0.602 ENST00000419067.2
ENST00000378717.4
IMPDH1

IMP (inosine 5'-monophosphate) dehydrogenase 1

chr6_-_99797522 0.600 ENST00000389677.5
FAXC
failed axon connections homolog (Drosophila)
chrX_-_106959631 0.584 ENST00000486554.1
ENST00000372390.4
TSC22D3

TSC22 domain family, member 3

chr4_+_113066552 0.563 ENST00000309733.5
C4orf32
chromosome 4 open reading frame 32
chr6_+_43737939 0.552 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr6_-_43596899 0.551 ENST00000307126.5
ENST00000452781.1
GTPBP2

GTP binding protein 2

chr2_+_211342432 0.544 ENST00000430249.2
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr3_+_99357319 0.543 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
COL8A1


collagen, type VIII, alpha 1


chr18_-_28681950 0.539 ENST00000251081.6
DSC2
desmocollin 2
chr5_-_146833485 0.539 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr10_-_75634260 0.538 ENST00000372765.1
ENST00000351293.3
CAMK2G

calcium/calmodulin-dependent protein kinase II gamma

chr17_-_40575535 0.536 ENST00000357037.5
PTRF
polymerase I and transcript release factor
chr14_-_35182994 0.533 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr8_+_42752053 0.532 ENST00000307602.4
HOOK3
hook microtubule-tethering protein 3
chr4_-_80994210 0.523 ENST00000403729.2
ANTXR2
anthrax toxin receptor 2
chr12_-_69326940 0.510 ENST00000549781.1
ENST00000548262.1
ENST00000551568.1
ENST00000548954.1
CPM



carboxypeptidase M



chr16_-_19729502 0.510 ENST00000219837.7
KNOP1
lysine-rich nucleolar protein 1
chr15_+_42066632 0.507 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
MAPKBP1



mitogen-activated protein kinase binding protein 1



chr10_+_101419187 0.506 ENST00000370489.4
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr2_-_227664474 0.503 ENST00000305123.5
IRS1
insulin receptor substrate 1
chr4_+_99182593 0.501 ENST00000508213.1
ENST00000408927.3
ENST00000514122.1
ENST00000453712.2
ENST00000511212.1
ENST00000408900.3
ENST00000339360.5
RAP1GDS1






RAP1, GTP-GDP dissociation stimulator 1






chr6_+_15246501 0.499 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr11_+_117049445 0.498 ENST00000324225.4
ENST00000532960.1
SIDT2

SID1 transmembrane family, member 2

chr2_-_220094294 0.497 ENST00000436856.1
ENST00000428226.1
ENST00000409422.1
ENST00000431715.1
ENST00000457841.1
ENST00000439812.1
ENST00000361242.4
ENST00000396761.2
ATG9A







autophagy related 9A







chr1_+_203595903 0.490 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATP2B4


ATPase, Ca++ transporting, plasma membrane 4


chr11_-_119599794 0.473 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr9_+_124413873 0.471 ENST00000408936.3
DAB2IP
DAB2 interacting protein
chr14_+_55034599 0.470 ENST00000392067.3
ENST00000357634.3
SAMD4A

sterile alpha motif domain containing 4A

chrX_-_51239425 0.467 ENST00000375992.3
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr6_-_33547975 0.466 ENST00000442998.2
ENST00000360661.5
BAK1

BCL2-antagonist/killer 1

chr12_+_4382917 0.466 ENST00000261254.3
CCND2
cyclin D2
chrX_-_109561294 0.464 ENST00000372059.2
ENST00000262844.5
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr7_-_124405681 0.458 ENST00000303921.2
GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
chrX_-_71351678 0.443 ENST00000609883.1
ENST00000545866.1
RGAG4

retrotransposon gag domain containing 4

chr17_+_26662730 0.442 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr16_-_56459354 0.441 ENST00000290649.5
AMFR
autocrine motility factor receptor, E3 ubiquitin protein ligase
chr11_-_102962929 0.436 ENST00000260247.5
DCUN1D5
DCN1, defective in cullin neddylation 1, domain containing 5
chrY_+_15016725 0.435 ENST00000336079.3
DDX3Y
DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked
chr1_-_244013384 0.431 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr19_-_47249679 0.431 ENST00000263280.6
STRN4
striatin, calmodulin binding protein 4
chr6_+_30524663 0.427 ENST00000376560.3
PRR3
proline rich 3
chr6_+_70576457 0.423 ENST00000322773.4
COL19A1
collagen, type XIX, alpha 1
chr13_-_103451307 0.422 ENST00000376004.4
KDELC1
KDEL (Lys-Asp-Glu-Leu) containing 1
chr13_+_109248500 0.422 ENST00000356711.2
MYO16
myosin XVI
chr20_+_306221 0.421 ENST00000342665.2
SOX12
SRY (sex determining region Y)-box 12
chr5_-_43313574 0.417 ENST00000325110.6
ENST00000433297.2
HMGCS1

3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)

chr11_+_75273101 0.405 ENST00000533603.1
ENST00000358171.3
ENST00000526242.1
SERPINH1


serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1)


chr12_+_13349650 0.400 ENST00000256951.5
ENST00000431267.2
ENST00000542474.1
ENST00000544053.1
EMP1



epithelial membrane protein 1



chr11_-_117186946 0.395 ENST00000313005.6
ENST00000528053.1
BACE1

beta-site APP-cleaving enzyme 1

chr2_+_70142189 0.391 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr8_-_82024290 0.388 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr4_-_10458982 0.382 ENST00000326756.3
ZNF518B
zinc finger protein 518B
chr19_+_34287751 0.382 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15



potassium channel tetramerization domain containing 15



chr4_+_124320665 0.380 ENST00000394339.2
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chr12_+_60083118 0.378 ENST00000261187.4
ENST00000543448.1
SLC16A7

solute carrier family 16 (monocarboxylate transporter), member 7

chr20_-_25604811 0.377 ENST00000304788.3
NANP
N-acetylneuraminic acid phosphatase
chr11_+_60691924 0.376 ENST00000544065.1
ENST00000453848.2
ENST00000005286.4
TMEM132A


transmembrane protein 132A


chr3_+_43732362 0.376 ENST00000458276.2
ABHD5
abhydrolase domain containing 5
chr5_-_157002775 0.373 ENST00000257527.4
ADAM19
ADAM metallopeptidase domain 19
chr5_-_122372354 0.372 ENST00000306442.4
PPIC
peptidylprolyl isomerase C (cyclophilin C)
chr1_-_166028709 0.365 ENST00000595430.1
AL626787.1
AL626787.1
chr12_-_8088871 0.364 ENST00000075120.7
SLC2A3
solute carrier family 2 (facilitated glucose transporter), member 3
chr12_-_28124903 0.357 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH


parathyroid hormone-like hormone


chr15_+_79724858 0.356 ENST00000305428.3
KIAA1024
KIAA1024
chr18_+_29027696 0.353 ENST00000257189.4
DSG3
desmoglein 3
chr18_-_24445729 0.352 ENST00000383168.4
AQP4
aquaporin 4
chr14_+_75745477 0.351 ENST00000303562.4
ENST00000554617.1
ENST00000554212.1
ENST00000535987.1
ENST00000555242.1
FOS




FBJ murine osteosarcoma viral oncogene homolog




chr6_-_30043539 0.348 ENST00000376751.3
ENST00000244360.6
RNF39

ring finger protein 39

chr3_-_57678772 0.346 ENST00000311128.5
DENND6A
DENN/MADD domain containing 6A
chr8_-_66754172 0.345 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chr1_+_40627038 0.344 ENST00000372771.4
RLF
rearranged L-myc fusion
chr3_+_158991025 0.344 ENST00000337808.6
IQCJ-SCHIP1
IQCJ-SCHIP1 readthrough
chr22_+_40390930 0.333 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr15_+_52121822 0.332 ENST00000558455.1
ENST00000308580.7
TMOD3

tropomodulin 3 (ubiquitous)

chr11_+_35965531 0.332 ENST00000528989.1
ENST00000524419.1
ENST00000315571.5
LDLRAD3


low density lipoprotein receptor class A domain containing 3


chr3_+_159557637 0.330 ENST00000445224.2
SCHIP1
schwannomin interacting protein 1
chr2_-_96811170 0.330 ENST00000288943.4
DUSP2
dual specificity phosphatase 2
chr7_+_73442102 0.329 ENST00000445912.1
ENST00000252034.7
ELN

elastin

chr2_-_134326009 0.328 ENST00000409261.1
ENST00000409213.1
NCKAP5

NCK-associated protein 5

chr12_+_104359576 0.326 ENST00000392872.3
ENST00000436021.2
TDG

thymine-DNA glycosylase

chr6_+_142468361 0.321 ENST00000367630.4
VTA1
vesicle (multivesicular body) trafficking 1
chr2_+_48541776 0.319 ENST00000413569.1
ENST00000340553.3
FOXN2

forkhead box N2

chr1_-_27816556 0.318 ENST00000536657.1
WASF2
WAS protein family, member 2
chr11_+_66188475 0.315 ENST00000311034.2
NPAS4
neuronal PAS domain protein 4
chr12_-_133464151 0.314 ENST00000315585.7
ENST00000266880.7
ENST00000443047.2
ENST00000432561.2
ENST00000450056.2
CHFR




checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase




chr20_+_34700333 0.313 ENST00000441639.1
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr12_+_88536067 0.313 ENST00000549011.1
ENST00000266712.6
ENST00000551088.1
TMTC3


transmembrane and tetratricopeptide repeat containing 3


chr4_+_128703295 0.309 ENST00000296464.4
ENST00000508549.1
HSPA4L

heat shock 70kDa protein 4-like

chr5_+_149887672 0.309 ENST00000261797.6
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr19_-_16738984 0.308 ENST00000600060.1
ENST00000263390.3
MED26

mediator complex subunit 26

chrX_+_21958674 0.308 ENST00000404933.2
SMS
spermine synthase
chr3_+_182971018 0.305 ENST00000326505.3
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr9_-_34126730 0.304 ENST00000361264.4
DCAF12
DDB1 and CUL4 associated factor 12
chr7_-_28220354 0.303 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr11_-_101454658 0.302 ENST00000344327.3
TRPC6
transient receptor potential cation channel, subfamily C, member 6
chr20_+_30555805 0.302 ENST00000562532.2
XKR7
XK, Kell blood group complex subunit-related family, member 7
chr9_+_112403088 0.301 ENST00000448454.2
PALM2
paralemmin 2
chr6_+_125283566 0.294 ENST00000521654.2
RNF217
ring finger protein 217
chr5_+_176560742 0.289 ENST00000439151.2
NSD1
nuclear receptor binding SET domain protein 1
chr22_-_39096661 0.289 ENST00000216039.5
JOSD1
Josephin domain containing 1
chr1_+_184356188 0.288 ENST00000235307.6
C1orf21
chromosome 1 open reading frame 21
chr10_-_33246722 0.287 ENST00000437302.1
ENST00000396033.2
ITGB1

integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)

chr12_+_50898881 0.286 ENST00000301180.5
DIP2B
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chrX_+_9754461 0.285 ENST00000380913.3
SHROOM2
shroom family member 2
chr12_+_56915713 0.284 ENST00000262031.5
ENST00000552247.2
RBMS2

RNA binding motif, single stranded interacting protein 2

chrX_+_107683096 0.282 ENST00000328300.6
ENST00000361603.2
COL4A5

collagen, type IV, alpha 5

chr17_-_41623716 0.282 ENST00000319349.5
ETV4
ets variant 4
chr2_+_208576355 0.281 ENST00000420822.1
ENST00000295414.3
ENST00000339882.5
CCNYL1


cyclin Y-like 1


chr15_-_55562582 0.281 ENST00000396307.2
RAB27A
RAB27A, member RAS oncogene family
chr18_+_59992527 0.279 ENST00000586569.1
TNFRSF11A
tumor necrosis factor receptor superfamily, member 11a, NFKB activator
chr1_+_218519577 0.278 ENST00000366930.4
ENST00000366929.4
TGFB2

transforming growth factor, beta 2

chr1_-_3447967 0.276 ENST00000294599.4
MEGF6
multiple EGF-like-domains 6
chr6_+_64281906 0.275 ENST00000370651.3
PTP4A1
protein tyrosine phosphatase type IVA, member 1
chr5_-_141704566 0.274 ENST00000344120.4
ENST00000434127.2
SPRY4

sprouty homolog 4 (Drosophila)

chr17_-_57784755 0.274 ENST00000537860.1
ENST00000393038.2
ENST00000409433.2
PTRH2


peptidyl-tRNA hydrolase 2


chr7_+_116139424 0.267 ENST00000222693.4
CAV2
caveolin 2
chr5_+_14664762 0.263 ENST00000284274.4
FAM105B
family with sequence similarity 105, member B
chr14_+_103851712 0.263 ENST00000440884.3
ENST00000416682.2
ENST00000429436.2
ENST00000303622.9
MARK3



MAP/microtubule affinity-regulating kinase 3



chr10_+_12110963 0.263 ENST00000263035.4
ENST00000437298.1
DHTKD1

dehydrogenase E1 and transketolase domain containing 1

chr8_-_125384927 0.262 ENST00000297632.6
TMEM65
transmembrane protein 65
chr15_-_72612470 0.261 ENST00000287202.5
CELF6
CUGBP, Elav-like family member 6
chr3_+_25469724 0.261 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr4_-_157892498 0.261 ENST00000502773.1
PDGFC
platelet derived growth factor C
chr1_+_165796753 0.260 ENST00000367879.4
UCK2
uridine-cytidine kinase 2
chr13_+_41363581 0.259 ENST00000338625.4
SLC25A15
solute carrier family 25 (mitochondrial carrier; ornithine transporter) member 15
chrX_+_73641286 0.259 ENST00000587091.1
SLC16A2
solute carrier family 16, member 2 (thyroid hormone transporter)
chr8_+_11141925 0.257 ENST00000221086.3
MTMR9
myotubularin related protein 9
chr14_-_99737565 0.256 ENST00000357195.3
BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr10_+_80828774 0.256 ENST00000334512.5
ZMIZ1
zinc finger, MIZ-type containing 1
chr10_+_18948311 0.255 ENST00000377275.3
ARL5B
ADP-ribosylation factor-like 5B
chr3_+_191046810 0.253 ENST00000392455.3
ENST00000392456.3
CCDC50

coiled-coil domain containing 50

chr4_+_144257915 0.252 ENST00000262995.4
GAB1
GRB2-associated binding protein 1
chr17_+_38333263 0.249 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1




Rap guanine nucleotide exchange factor (GEF)-like 1




chr19_+_47104493 0.249 ENST00000291295.9
ENST00000597743.1
CALM3

calmodulin 3 (phosphorylase kinase, delta)

chr7_+_106809406 0.246 ENST00000468410.1
ENST00000478930.1
ENST00000464009.1
ENST00000222574.4
HBP1



HMG-box transcription factor 1



chr10_+_105036909 0.246 ENST00000369849.4
INA
internexin neuronal intermediate filament protein, alpha
chr12_+_112563335 0.245 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAFD1



TRAF-type zinc finger domain containing 1



chr17_-_28618948 0.243 ENST00000261714.6
BLMH
bleomycin hydrolase
chr3_-_119813264 0.240 ENST00000264235.8
GSK3B
glycogen synthase kinase 3 beta
chr1_+_215740709 0.240 ENST00000259154.4
KCTD3
potassium channel tetramerization domain containing 3
chr12_-_8025442 0.239 ENST00000340749.5
ENST00000535295.1
ENST00000539234.1
SLC2A14


solute carrier family 2 (facilitated glucose transporter), member 14


chr9_+_5629025 0.237 ENST00000251879.6
ENST00000414202.2
KIAA1432

KIAA1432

chr3_-_36781352 0.237 ENST00000416516.2
DCLK3
doublecortin-like kinase 3
chr15_+_68570062 0.235 ENST00000306917.4
FEM1B
fem-1 homolog b (C. elegans)
chr2_-_208634287 0.234 ENST00000295417.3
FZD5
frizzled family receptor 5
chr5_-_78809950 0.233 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chr15_+_73976545 0.228 ENST00000318443.5
ENST00000537340.2
ENST00000318424.5
CD276


CD276 molecule


chr19_-_44100275 0.228 ENST00000422989.1
ENST00000598324.1
IRGQ

immunity-related GTPase family, Q

chr9_-_123555655 0.227 ENST00000340778.5
ENST00000453291.1
ENST00000608872.1
FBXW2


F-box and WD repeat domain containing 2


chr11_+_74459876 0.227 ENST00000299563.4
RNF169
ring finger protein 169
chr12_-_6451235 0.224 ENST00000440083.2
ENST00000162749.2
TNFRSF1A

tumor necrosis factor receptor superfamily, member 1A

chr17_-_7297833 0.224 ENST00000571802.1
ENST00000576201.1
ENST00000573213.1
ENST00000324822.11
TMEM256-PLSCR3



TMEM256-PLSCR3 readthrough (NMD candidate)



chr1_+_206557366 0.224 ENST00000414007.1
ENST00000419187.2
SRGAP2

SLIT-ROBO Rho GTPase activating protein 2

chr6_+_106959718 0.223 ENST00000369066.3
AIM1
absent in melanoma 1
chr20_+_42295745 0.222 ENST00000396863.4
ENST00000217026.4
MYBL2

v-myb avian myeloblastosis viral oncogene homolog-like 2

chr7_-_25019760 0.222 ENST00000352860.1
ENST00000353930.1
ENST00000431825.2
ENST00000313367.2
OSBPL3



oxysterol binding protein-like 3



chr20_-_32700075 0.222 ENST00000374980.2
EIF2S2
eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa
chr15_-_68724490 0.222 ENST00000315757.7
ENST00000423218.2
ITGA11

integrin, alpha 11

chr10_+_89622870 0.221 ENST00000371953.3
PTEN
phosphatase and tensin homolog
chr6_+_53883708 0.219 ENST00000514921.1
ENST00000274897.5
ENST00000370877.2
MLIP


muscular LMNA-interacting protein


chrX_+_115567767 0.217 ENST00000371900.4
SLC6A14
solute carrier family 6 (amino acid transporter), member 14
chr9_+_116917807 0.217 ENST00000356083.3
COL27A1
collagen, type XXVII, alpha 1
chr3_-_122233723 0.216 ENST00000493510.1
ENST00000344337.6
ENST00000476916.1
ENST00000465882.1
KPNA1



karyopherin alpha 1 (importin alpha 5)



chrX_+_41192595 0.215 ENST00000399959.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr14_+_103058948 0.215 ENST00000262241.6
RCOR1
REST corepressor 1
chr1_+_50574585 0.211 ENST00000371824.1
ENST00000371823.4
ELAVL4

ELAV like neuron-specific RNA binding protein 4

chr16_-_23160591 0.210 ENST00000219689.7
USP31
ubiquitin specific peptidase 31
chr7_-_92463210 0.209 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr5_+_157170703 0.206 ENST00000286307.5
LSM11
LSM11, U7 small nuclear RNA associated
chr17_+_21279509 0.203 ENST00000583088.1
KCNJ12
potassium inwardly-rectifying channel, subfamily J, member 12
chr6_-_110500905 0.202 ENST00000392587.2
WASF1
WAS protein family, member 1
chr16_-_67217844 0.202 ENST00000563902.1
ENST00000561621.1
ENST00000290881.7
KIAA0895L


KIAA0895-like


chr12_+_62654119 0.201 ENST00000353364.3
ENST00000549523.1
ENST00000280377.5
USP15


ubiquitin specific peptidase 15


chr22_-_36236265 0.198 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2




RNA binding protein, fox-1 homolog (C. elegans) 2





Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0006154 adenosine catabolic process(GO:0006154) inosine biosynthetic process(GO:0046103)
0.3 1.0 GO:0044691 tooth eruption(GO:0044691)
0.3 1.0 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.3 0.9 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.7 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.2 1.9 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.2 0.6 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 1.3 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.2 0.5 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.2 0.5 GO:0031077 post-embryonic camera-type eye development(GO:0031077)
0.1 0.5 GO:0071400 cellular response to oleic acid(GO:0071400)
0.1 0.6 GO:0051541 elastin metabolic process(GO:0051541)
0.1 0.4 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 0.5 GO:0044805 late nucleophagy(GO:0044805)
0.1 1.6 GO:0038065 collagen-activated signaling pathway(GO:0038065)
0.1 0.7 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.3 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.6 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.7 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.1 0.5 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.3 GO:0071812 circadian temperature homeostasis(GO:0060086) regulation of fever generation by regulation of prostaglandin secretion(GO:0071810) positive regulation of fever generation by positive regulation of prostaglandin secretion(GO:0071812) positive regulation of ERK1 and ERK2 cascade via TNFSF11-mediated signaling(GO:0071848) regulation of fever generation by prostaglandin secretion(GO:0100009)
0.1 0.3 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) negative regulation of alkaline phosphatase activity(GO:0010693) uterine wall breakdown(GO:0042704) positive regulation of catagen(GO:0051795) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.4 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.2 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 0.3 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 0.3 GO:1902544 regulation of DNA N-glycosylase activity(GO:1902544)
0.1 0.8 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 0.2 GO:0071109 superior temporal gyrus development(GO:0071109) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.1 0.3 GO:1904862 inhibitory synapse assembly(GO:1904862)
0.1 0.5 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.2 GO:0021816 lamellipodium assembly involved in ameboidal cell migration(GO:0003363) extension of a leading process involved in cell motility in cerebral cortex radial glia guided migration(GO:0021816)
0.1 0.1 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.1 0.5 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.1 0.3 GO:0010710 regulation of collagen catabolic process(GO:0010710)
0.1 0.6 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.1 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 1.3 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.1 0.3 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.1 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 0.6 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.1 0.7 GO:0086042 cardiac muscle cell-cardiac muscle cell adhesion(GO:0086042)
0.1 0.2 GO:0060743 epithelial cell maturation involved in prostate gland development(GO:0060743)
0.1 0.2 GO:1903984 negative regulation of ribosome biogenesis(GO:0090071) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.5 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 1.8 GO:0032332 positive regulation of chondrocyte differentiation(GO:0032332)
0.1 0.4 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.6 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.1 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.1 0.5 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 3.9 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.0 1.7 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.0 0.3 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.5 GO:0045964 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.4 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0031064 negative regulation of histone deacetylation(GO:0031064)
0.0 0.1 GO:0043686 co-translational protein modification(GO:0043686)
0.0 0.3 GO:1903352 L-ornithine transmembrane transport(GO:1903352)
0.0 0.3 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:0043418 homocysteine catabolic process(GO:0043418)
0.0 0.5 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.0 0.3 GO:0060161 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791) positive regulation of dopamine receptor signaling pathway(GO:0060161)
0.0 0.0 GO:1904580 regulation of intracellular mRNA localization(GO:1904580) positive regulation of intracellular mRNA localization(GO:1904582)
0.0 0.7 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.1 GO:1905064 metanephric glomerular mesangial cell development(GO:0072255) reversible differentiation(GO:0090677) cell dedifferentiation involved in phenotypic switching(GO:0090678) positive regulation of phenotypic switching(GO:1900241) negative regulation of vascular smooth muscle cell differentiation(GO:1905064) regulation of vascular smooth muscle cell dedifferentiation(GO:1905174) positive regulation of vascular smooth muscle cell dedifferentiation(GO:1905176) vascular smooth muscle cell dedifferentiation(GO:1990936)
0.0 0.1 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.4 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.1 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:1903028 positive regulation of opsonization(GO:1903028)
0.0 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.1 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.0 0.2 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.2 GO:0060282 positive regulation of oocyte development(GO:0060282)
0.0 0.9 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.4 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.0 0.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.2 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.5 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.4 GO:0033197 response to vitamin E(GO:0033197)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.2 GO:1902019 regulation of cilium movement involved in cell motility(GO:0060295) regulation of cilium beat frequency involved in ciliary motility(GO:0060296) regulation of cilium-dependent cell motility(GO:1902019)
0.0 0.3 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.5 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.2 GO:1903898 negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.2 GO:0036093 male germ cell proliferation(GO:0002176) germ cell proliferation(GO:0036093)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.0 GO:1900222 negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.5 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.0 0.1 GO:0071469 cellular response to alkaline pH(GO:0071469)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 0.3 GO:1904896 ESCRT complex disassembly(GO:1904896) ESCRT III complex disassembly(GO:1904903)
0.0 0.2 GO:0010713 negative regulation of collagen metabolic process(GO:0010713) negative regulation of collagen biosynthetic process(GO:0032966)
0.0 0.3 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.2 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.3 GO:0021942 radial glia guided migration of Purkinje cell(GO:0021942)
0.0 0.1 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.0 0.2 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.5 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.2 GO:0090205 positive regulation of cholesterol metabolic process(GO:0090205)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.1 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 0.0 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.2 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.2 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.0 0.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.8 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.0 0.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205)
0.0 0.2 GO:0002063 chondrocyte development(GO:0002063)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.5 GO:0008360 regulation of cell shape(GO:0008360)
0.0 0.3 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.3 GO:0032060 bleb assembly(GO:0032060)
0.0 0.1 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.2 GO:0061036 positive regulation of cartilage development(GO:0061036)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.3 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.4 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.0 GO:0061582 intestinal epithelial cell migration(GO:0061582)
0.0 0.1 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.2 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.1 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.2 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.7 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.2 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.1 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.0 0.0 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.0 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.3 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.0 0.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.2 GO:0033235 positive regulation of protein sumoylation(GO:0033235)
0.0 0.0 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.4 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.3 0.9 GO:0005588 collagen type V trimer(GO:0005588)
0.3 1.1 GO:0030934 anchoring collagen complex(GO:0030934)
0.2 0.7 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.2 0.5 GO:0034681 integrin alpha11-beta1 complex(GO:0034681)
0.2 0.5 GO:1990032 parallel fiber(GO:1990032)
0.1 0.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 1.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.5 GO:0005899 insulin receptor complex(GO:0005899)
0.1 0.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 0.2 GO:0031523 Myb complex(GO:0031523)
0.1 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.2 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.1 1.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.7 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.4 GO:0035976 AP1 complex(GO:0035976)
0.0 0.3 GO:0071953 elastic fiber(GO:0071953)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.3 GO:0005593 FACIT collagen trimer(GO:0005593)
0.0 0.2 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.4 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.5 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.9 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683)
0.0 0.7 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.4 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0042565 RNA nuclear export complex(GO:0042565)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0042587 glycogen granule(GO:0042587)
0.0 0.2 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0042272 nuclear RNA export factor complex(GO:0042272)
0.0 0.0 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.0 1.8 GO:0005604 basement membrane(GO:0005604)
0.0 0.5 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.5 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.8 GO:0031941 filamentous actin(GO:0031941)
0.0 0.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.5 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 1.5 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.3 GO:0014704 intercalated disc(GO:0014704)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.3 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.3 1.7 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.3 1.0 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.3 0.8 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.2 0.5 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2 0.5 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.2 0.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.4 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.7 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.4 GO:0008798 beta-aspartyl-peptidase activity(GO:0008798)
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.3 GO:0043739 G/U mismatch-specific uracil-DNA glycosylase activity(GO:0043739)
0.1 0.4 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.1 0.6 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.3 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.4 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.6 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.4 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.5 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.5 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.3 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.4 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 1.2 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.6 GO:0043426 MRF binding(GO:0043426)
0.1 0.2 GO:0030350 iron-responsive element binding(GO:0030350)
0.1 0.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.5 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.2 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.1 0.2 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 0.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.2 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.3 GO:0047238 glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047238)
0.0 0.3 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.0 0.5 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 4.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 0.2 GO:0004096 catalase activity(GO:0004096)
0.0 0.0 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.0 0.4 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.2 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.3 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.0 0.2 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.4 GO:0015250 water channel activity(GO:0015250)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.7 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 2.2 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.6 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.0 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.0 0.9 GO:0008028 monocarboxylic acid transmembrane transporter activity(GO:0008028)
0.0 0.2 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.0 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.0 0.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.4 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0050509 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509)
0.0 0.3 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.1 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.0 GO:0004947 bradykinin receptor activity(GO:0004947)
0.0 0.2 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0043176 amine binding(GO:0043176) serotonin binding(GO:0051378)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.0 GO:0098808 mRNA cap binding(GO:0098808)
0.0 0.0 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 7.6 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.9 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.8 PID_S1P_S1P3_PATHWAY S1P3 pathway
0.0 1.0 PID_S1P_S1P2_PATHWAY S1P2 pathway
0.0 1.8 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 0.7 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.6 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 1.8 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.9 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.8 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.7 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.5 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.6 PID_EPO_PATHWAY EPO signaling pathway
0.0 1.1 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.1 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 0.4 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.7 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.3 PID_ANTHRAX_PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 0.3 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.1 1.3 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 0.7 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 1.3 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.2 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.7 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.0 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.8 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.7 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.6 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.6 REACTOME_SOS_MEDIATED_SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.4 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME_SIGNALLING_TO_P38_VIA_RIT_AND_RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.6 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.3 REACTOME_BASE_FREE_SUGAR_PHOSPHATE_REMOVAL_VIA_THE_SINGLE_NUCLEOTIDE_REPLACEMENT_PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.7 REACTOME_RNA_POL_I_TRANSCRIPTION_TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.4 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME_SEROTONIN_RECEPTORS Genes involved in Serotonin receptors
0.0 0.4 REACTOME_PHOSPHORYLATION_OF_CD3_AND_TCR_ZETA_CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.5 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME_SLBP_DEPENDENT_PROCESSING_OF_REPLICATION_DEPENDENT_HISTONE_PRE_MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.7 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.2 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.1 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)