Motif ID: AGCUGCC

Z-value: 0.431


Mature miRNA associated with seed AGCUGCC:

NamemiRBase Accession
hsa-miR-22-3p MIMAT0000077



Activity profile for motif AGCUGCC.

activity profile for motif AGCUGCC


Sorted Z-values histogram for motif AGCUGCC

Sorted Z-values for motif AGCUGCC



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCUGCC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_+_125133315 0.445 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr5_-_100238956 0.378 ENST00000231461.5
ST8SIA4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr5_-_146833485 0.360 ENST00000398514.3
DPYSL3
dihydropyrimidinase-like 3
chr1_-_244013384 0.342 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr5_-_127873659 0.317 ENST00000262464.4
FBN2
fibrillin 2
chr17_-_16256718 0.300 ENST00000476243.1
ENST00000299736.4
CENPV

centromere protein V

chr19_-_46234119 0.293 ENST00000317683.3
FBXO46
F-box protein 46
chr12_+_93965451 0.276 ENST00000548537.1
SOCS2
suppressor of cytokine signaling 2
chr22_+_38071615 0.270 ENST00000215909.5
LGALS1
lectin, galactoside-binding, soluble, 1
chr1_+_26438289 0.263 ENST00000374271.4
ENST00000374269.1
PDIK1L

PDLIM1 interacting kinase 1 like

chr16_+_10971037 0.255 ENST00000324288.8
ENST00000381835.5
CIITA

class II, major histocompatibility complex, transactivator

chr10_+_69644404 0.241 ENST00000212015.6
SIRT1
sirtuin 1
chr1_-_63988846 0.240 ENST00000283568.8
ENST00000371092.3
ENST00000271002.10
ITGB3BP


integrin beta 3 binding protein (beta3-endonexin)


chr11_-_95657231 0.230 ENST00000409459.1
ENST00000352297.7
ENST00000393223.3
ENST00000346299.5
MTMR2



myotubularin related protein 2



chr1_+_184356188 0.228 ENST00000235307.6
C1orf21
chromosome 1 open reading frame 21
chr5_-_159739532 0.219 ENST00000520748.1
ENST00000393977.3
ENST00000257536.7
CCNJL


cyclin J-like


chr11_-_115375107 0.213 ENST00000545380.1
ENST00000452722.3
ENST00000537058.1
ENST00000536727.1
ENST00000542447.2
ENST00000331581.6
CADM1





cell adhesion molecule 1





chr7_+_73703728 0.204 ENST00000361545.5
ENST00000223398.6
CLIP2

CAP-GLY domain containing linker protein 2

chr5_+_57878859 0.202 ENST00000282878.4
RAB3C
RAB3C, member RAS oncogene family
chr10_+_89622870 0.197 ENST00000371953.3
PTEN
phosphatase and tensin homolog
chr3_-_135914615 0.192 ENST00000309993.2
MSL2
male-specific lethal 2 homolog (Drosophila)
chr1_-_114355083 0.182 ENST00000261441.5
RSBN1
round spermatid basic protein 1
chr7_-_35734730 0.181 ENST00000396081.1
ENST00000311350.3
HERPUD2

HERPUD family member 2

chr16_+_66878814 0.181 ENST00000394069.3
CA7
carbonic anhydrase VII
chr12_+_56401268 0.181 ENST00000262032.5
IKZF4
IKAROS family zinc finger 4 (Eos)
chr1_+_192778161 0.178 ENST00000235382.5
RGS2
regulator of G-protein signaling 2, 24kDa
chr10_+_78078088 0.175 ENST00000496424.2
C10orf11
chromosome 10 open reading frame 11
chr4_-_78740511 0.173 ENST00000504123.1
ENST00000264903.4
ENST00000515441.1
CNOT6L


CCR4-NOT transcription complex, subunit 6-like


chr2_-_213403565 0.164 ENST00000342788.4
ENST00000436443.1
ERBB4

v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4

chr11_-_88796803 0.162 ENST00000418177.2
ENST00000455756.2
GRM5

glutamate receptor, metabotropic 5

chr5_-_136834982 0.155 ENST00000510689.1
ENST00000394945.1
SPOCK1

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1

chr12_+_49372251 0.154 ENST00000293549.3
WNT1
wingless-type MMTV integration site family, member 1
chr2_-_166651191 0.148 ENST00000392701.3
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr1_+_182992545 0.145 ENST00000258341.4
LAMC1
laminin, gamma 1 (formerly LAMB2)
chr7_+_30323923 0.141 ENST00000323037.4
ZNRF2
zinc and ring finger 2
chr1_-_153895377 0.141 ENST00000368655.4
GATAD2B
GATA zinc finger domain containing 2B
chr5_-_149492904 0.139 ENST00000286301.3
ENST00000511344.1
CSF1R

colony stimulating factor 1 receptor

chr8_+_17354587 0.137 ENST00000494857.1
ENST00000522656.1
SLC7A2

solute carrier family 7 (cationic amino acid transporter, y+ system), member 2

chr7_+_128577972 0.129 ENST00000357234.5
ENST00000477535.1
ENST00000479582.1
ENST00000464557.1
ENST00000402030.2
IRF5




interferon regulatory factor 5




chr8_+_1449532 0.129 ENST00000421627.2
DLGAP2
discs, large (Drosophila) homolog-associated protein 2
chr4_+_184826418 0.128 ENST00000308497.4
ENST00000438269.1
STOX2

storkhead box 2

chr9_+_116638562 0.126 ENST00000374126.5
ENST00000288466.7
ZNF618

zinc finger protein 618

chr6_-_43478239 0.124 ENST00000372441.1
LRRC73
leucine rich repeat containing 73
chr7_-_106301405 0.123 ENST00000523505.1
CCDC71L
coiled-coil domain containing 71-like
chr2_-_240322643 0.120 ENST00000345617.3
HDAC4
histone deacetylase 4
chr6_+_53659746 0.118 ENST00000370888.1
LRRC1
leucine rich repeat containing 1
chr10_+_72238517 0.115 ENST00000263563.6
PALD1
phosphatase domain containing, paladin 1
chrX_-_54070607 0.115 ENST00000338154.6
ENST00000338946.6
PHF8

PHD finger protein 8

chr11_+_120207787 0.114 ENST00000397843.2
ENST00000356641.3
ARHGEF12

Rho guanine nucleotide exchange factor (GEF) 12

chr17_-_19771216 0.114 ENST00000395544.4
ULK2
unc-51 like autophagy activating kinase 2
chr11_-_126870655 0.113 ENST00000525144.2
KIRREL3
kin of IRRE like 3 (Drosophila)
chr6_-_62996066 0.109 ENST00000281156.4
KHDRBS2
KH domain containing, RNA binding, signal transduction associated 2
chr17_+_47865917 0.106 ENST00000259021.4
ENST00000454930.2
ENST00000509773.1
ENST00000510819.1
ENST00000424009.2
KAT7




K(lysine) acetyltransferase 7




chr15_-_37390482 0.106 ENST00000559085.1
ENST00000397624.3
MEIS2

Meis homeobox 2

chr19_+_34745442 0.103 ENST00000299505.6
ENST00000588470.1
ENST00000589583.1
ENST00000588338.2
KIAA0355



KIAA0355



chr10_-_75634260 0.102 ENST00000372765.1
ENST00000351293.3
CAMK2G

calcium/calmodulin-dependent protein kinase II gamma

chr7_-_44924939 0.101 ENST00000395699.2
PURB
purine-rich element binding protein B
chr6_-_152958521 0.099 ENST00000367255.5
ENST00000265368.4
ENST00000448038.1
ENST00000341594.5
SYNE1



spectrin repeat containing, nuclear envelope 1



chr22_+_41487711 0.097 ENST00000263253.7
EP300
E1A binding protein p300
chr1_+_6673745 0.096 ENST00000377648.4
PHF13
PHD finger protein 13
chr22_+_41777927 0.096 ENST00000266304.4
TEF
thyrotrophic embryonic factor
chr11_+_65101225 0.096 ENST00000528416.1
ENST00000415073.2
ENST00000252268.4
DPF2


D4, zinc and double PHD fingers family 2


chr1_-_204380919 0.095 ENST00000367188.4
PPP1R15B
protein phosphatase 1, regulatory subunit 15B
chr9_+_116207007 0.095 ENST00000374140.2
RGS3
regulator of G-protein signaling 3
chr16_+_31044812 0.093 ENST00000313843.3
STX4
syntaxin 4
chr9_+_132815985 0.093 ENST00000372410.3
GPR107
G protein-coupled receptor 107
chr1_+_52870227 0.092 ENST00000257181.9
PRPF38A
pre-mRNA processing factor 38A
chr22_+_40390930 0.091 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr16_+_27561449 0.088 ENST00000261588.4
KIAA0556
KIAA0556
chr15_+_57668695 0.088 ENST00000281282.5
CGNL1
cingulin-like 1
chr15_+_51633826 0.087 ENST00000335449.6
GLDN
gliomedin
chr4_+_184020398 0.087 ENST00000403733.3
ENST00000378925.3
WWC2

WW and C2 domain containing 2

chrX_+_108780062 0.086 ENST00000372106.1
NXT2
nuclear transport factor 2-like export factor 2
chr1_-_149889382 0.083 ENST00000369145.1
ENST00000369146.3
SV2A

synaptic vesicle glycoprotein 2A

chr10_-_32636106 0.083 ENST00000263062.8
ENST00000319778.6
EPC1

enhancer of polycomb homolog 1 (Drosophila)

chr5_+_56469775 0.083 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr12_-_53893399 0.082 ENST00000267079.2
MAP3K12
mitogen-activated protein kinase kinase kinase 12
chr2_+_232651124 0.081 ENST00000350033.3
ENST00000412591.1
ENST00000410017.1
ENST00000373608.3
COPS7B



COP9 signalosome subunit 7B



chr1_-_212873267 0.081 ENST00000243440.1
BATF3
basic leucine zipper transcription factor, ATF-like 3
chr6_-_110500905 0.081 ENST00000392587.2
WASF1
WAS protein family, member 1
chr14_-_67982146 0.079 ENST00000557779.1
ENST00000557006.1
TMEM229B

transmembrane protein 229B

chr1_-_10003372 0.078 ENST00000377223.1
ENST00000541052.1
ENST00000377213.1
LZIC


leucine zipper and CTNNBIP1 domain containing


chr17_-_47841485 0.078 ENST00000506156.1
ENST00000240364.2
FAM117A

family with sequence similarity 117, member A

chr2_-_99552620 0.078 ENST00000428096.1
ENST00000397899.2
ENST00000420294.1
KIAA1211L


KIAA1211-like


chr16_-_87525651 0.078 ENST00000268616.4
ZCCHC14
zinc finger, CCHC domain containing 14
chr1_-_115259337 0.078 ENST00000369535.4
NRAS
neuroblastoma RAS viral (v-ras) oncogene homolog
chr7_+_39989611 0.077 ENST00000181839.4
CDK13
cyclin-dependent kinase 13
chr17_-_8055747 0.076 ENST00000317276.4
ENST00000581703.1
PER1

period circadian clock 1

chr15_+_44719394 0.075 ENST00000260327.4
ENST00000396780.1
CTDSPL2

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2

chr1_-_169863016 0.074 ENST00000367772.4
ENST00000367771.6
SCYL3

SCY1-like 3 (S. cerevisiae)

chr10_-_118032697 0.074 ENST00000439649.3
GFRA1
GDNF family receptor alpha 1
chr1_-_89357179 0.074 ENST00000448623.1
ENST00000418217.1
ENST00000370500.5
GTF2B


general transcription factor IIB


chr2_-_71454185 0.074 ENST00000244221.8
PAIP2B
poly(A) binding protein interacting protein 2B
chr9_-_14314066 0.074 ENST00000397575.3
NFIB
nuclear factor I/B
chrX_+_21392873 0.073 ENST00000379510.3
CNKSR2
connector enhancer of kinase suppressor of Ras 2
chr16_+_1756162 0.073 ENST00000250894.4
ENST00000356010.5
MAPK8IP3

mitogen-activated protein kinase 8 interacting protein 3

chr4_+_40058411 0.070 ENST00000261435.6
ENST00000515550.1
N4BP2

NEDD4 binding protein 2

chr7_+_20370746 0.069 ENST00000222573.4
ITGB8
integrin, beta 8
chr6_+_96463840 0.068 ENST00000302103.5
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr10_+_5454505 0.066 ENST00000355029.4
NET1
neuroepithelial cell transforming 1
chr17_+_38333263 0.066 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1




Rap guanine nucleotide exchange factor (GEF)-like 1




chr8_-_48651648 0.064 ENST00000408965.3
CEBPD
CCAAT/enhancer binding protein (C/EBP), delta
chr15_+_41851211 0.060 ENST00000263798.3
TYRO3
TYRO3 protein tyrosine kinase
chr22_-_22221900 0.059 ENST00000215832.6
ENST00000398822.3
MAPK1

mitogen-activated protein kinase 1

chr22_-_30783356 0.059 ENST00000382363.3
RNF215
ring finger protein 215
chr4_-_53525406 0.059 ENST00000451218.2
ENST00000441222.3
USP46

ubiquitin specific peptidase 46

chr10_+_92980517 0.058 ENST00000336126.5
PCGF5
polycomb group ring finger 5
chr1_-_15911510 0.058 ENST00000375826.3
AGMAT
agmatine ureohydrolase (agmatinase)
chr14_+_55738021 0.057 ENST00000313833.4
FBXO34
F-box protein 34
chr14_+_71108460 0.057 ENST00000256367.2
TTC9
tetratricopeptide repeat domain 9
chr21_+_40177143 0.057 ENST00000360214.3
ETS2
v-ets avian erythroblastosis virus E26 oncogene homolog 2
chr11_+_119076745 0.057 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chrX_+_123095155 0.056 ENST00000371160.1
ENST00000435103.1
STAG2

stromal antigen 2

chr10_-_99094458 0.056 ENST00000371019.2
FRAT2
frequently rearranged in advanced T-cell lymphomas 2
chr2_+_74881355 0.056 ENST00000357877.2
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr1_-_11863171 0.055 ENST00000376592.1
MTHFR
methylenetetrahydrofolate reductase (NAD(P)H)
chr16_+_30006615 0.055 ENST00000563197.1
INO80E
INO80 complex subunit E
chr1_+_180123969 0.054 ENST00000367602.3
ENST00000367600.5
QSOX1

quiescin Q6 sulfhydryl oxidase 1

chr7_-_79082867 0.054 ENST00000419488.1
ENST00000354212.4
MAGI2

membrane associated guanylate kinase, WW and PDZ domain containing 2

chr17_-_202579 0.054 ENST00000577079.1
ENST00000331302.7
ENST00000536489.2
RPH3AL


rabphilin 3A-like (without C2 domains)


chr17_+_60536002 0.053 ENST00000582809.1
TLK2
tousled-like kinase 2
chr6_-_134373732 0.053 ENST00000275230.5
SLC2A12
solute carrier family 2 (facilitated glucose transporter), member 12
chr1_+_114472222 0.051 ENST00000369558.1
ENST00000369561.4
HIPK1

homeodomain interacting protein kinase 1

chr4_-_41216619 0.051 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
APBB2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr5_+_149109825 0.051 ENST00000360453.4
ENST00000394320.3
ENST00000309241.5
PPARGC1B


peroxisome proliferator-activated receptor gamma, coactivator 1 beta


chr1_-_204329013 0.050 ENST00000272203.3
ENST00000414478.1
PLEKHA6

pleckstrin homology domain containing, family A member 6

chr6_+_15246501 0.050 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr4_-_87281224 0.049 ENST00000395169.3
ENST00000395161.2
MAPK10

mitogen-activated protein kinase 10

chr12_+_9067327 0.048 ENST00000433083.2
ENST00000544916.1
ENST00000544539.1
ENST00000539063.1
PHC1



polyhomeotic homolog 1 (Drosophila)



chr19_+_19303008 0.048 ENST00000353145.1
ENST00000421262.3
ENST00000303088.4
ENST00000456252.3
ENST00000593273.1
RFXANK




regulatory factor X-associated ankyrin-containing protein




chr1_-_213189108 0.047 ENST00000535388.1
ANGEL2
angel homolog 2 (Drosophila)
chr9_+_101867359 0.047 ENST00000374994.4
TGFBR1
transforming growth factor, beta receptor 1
chr3_+_43328004 0.046 ENST00000454177.1
ENST00000429705.2
ENST00000296088.7
ENST00000437827.1
SNRK



SNF related kinase



chr10_-_35930219 0.045 ENST00000374694.1
FZD8
frizzled family receptor 8
chr1_+_93544791 0.045 ENST00000545708.1
ENST00000540243.1
ENST00000370298.4
MTF2


metal response element binding transcription factor 2


chr9_+_87284622 0.044 ENST00000395882.1
NTRK2
neurotrophic tyrosine kinase, receptor, type 2
chr15_-_34502278 0.044 ENST00000559515.1
ENST00000256544.3
ENST00000560108.1
ENST00000559462.1
KATNBL1



katanin p80 subunit B-like 1



chr5_+_139927213 0.043 ENST00000310331.2
EIF4EBP3
eukaryotic translation initiation factor 4E binding protein 3
chr6_-_99873145 0.043 ENST00000369239.5
ENST00000438806.1
PNISR

PNN-interacting serine/arginine-rich protein

chr15_-_73661605 0.043 ENST00000261917.3
HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chrX_+_24483338 0.043 ENST00000379162.4
ENST00000441463.2
PDK3

pyruvate dehydrogenase kinase, isozyme 3

chr17_+_48912744 0.042 ENST00000311378.4
WFIKKN2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr4_+_20702059 0.042 ENST00000444671.2
ENST00000510700.1
ENST00000506745.1
ENST00000514663.1
ENST00000509469.1
ENST00000515339.1
ENST00000513861.1
ENST00000502374.1
ENST00000538990.1
ENST00000511160.1
ENST00000504630.1
ENST00000513590.1
ENST00000514292.1
ENST00000502938.1
ENST00000509625.1
ENST00000505160.1
ENST00000507634.1
ENST00000513459.1
ENST00000511089.1
PACRGL


















PARK2 co-regulated-like


















chr17_+_40118759 0.042 ENST00000393892.3
CNP
2',3'-cyclic nucleotide 3' phosphodiesterase
chr1_+_27561007 0.041 ENST00000319394.3
WDTC1
WD and tetratricopeptide repeats 1
chr16_+_24266874 0.041 ENST00000005284.3
CACNG3
calcium channel, voltage-dependent, gamma subunit 3
chr12_-_57400227 0.040 ENST00000300101.2
ZBTB39
zinc finger and BTB domain containing 39
chr12_-_86230315 0.040 ENST00000361228.3
RASSF9
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr11_-_75062730 0.039 ENST00000420843.2
ENST00000360025.3
ARRB1

arrestin, beta 1

chr5_+_142149955 0.038 ENST00000378004.3
ARHGAP26
Rho GTPase activating protein 26
chr12_+_113796347 0.038 ENST00000545182.2
ENST00000280800.3
PLBD2

phospholipase B domain containing 2

chr15_-_89456593 0.038 ENST00000558029.1
ENST00000539437.1
ENST00000542878.1
ENST00000268151.7
ENST00000566497.1
MFGE8




milk fat globule-EGF factor 8 protein




chr11_-_47788847 0.037 ENST00000263773.5
FNBP4
formin binding protein 4
chr2_+_166326157 0.037 ENST00000421875.1
ENST00000314499.7
ENST00000409664.1
CSRNP3


cysteine-serine-rich nuclear protein 3


chrX_-_112084043 0.037 ENST00000304758.1
AMOT
angiomotin
chr2_-_32264850 0.037 ENST00000295066.3
ENST00000342166.5
DPY30

dpy-30 homolog (C. elegans)

chr1_-_39347255 0.036 ENST00000454994.2
ENST00000357771.3
GJA9

gap junction protein, alpha 9, 59kDa

chr1_-_222885770 0.036 ENST00000355727.2
ENST00000340020.6
AIDA

axin interactor, dorsalization associated

chr2_-_175113301 0.036 ENST00000344357.5
ENST00000284719.3
OLA1

Obg-like ATPase 1

chr20_-_39995467 0.035 ENST00000332312.3
EMILIN3
elastin microfibril interfacer 3
chr7_+_31003621 0.035 ENST00000326139.2
GHRHR
growth hormone releasing hormone receptor
chr1_-_162381907 0.035 ENST00000367929.2
ENST00000359567.3
SH2D1B

SH2 domain containing 1B

chr10_+_76586348 0.035 ENST00000372724.1
ENST00000287239.4
ENST00000372714.1
KAT6B


K(lysine) acetyltransferase 6B


chr5_-_78809950 0.034 ENST00000334082.6
HOMER1
homer homolog 1 (Drosophila)
chr7_-_11871815 0.034 ENST00000423059.4
THSD7A
thrombospondin, type I, domain containing 7A
chr19_+_49468558 0.033 ENST00000331825.6
FTL
ferritin, light polypeptide
chr17_-_4890919 0.032 ENST00000572543.1
ENST00000381311.5
ENST00000348066.3
ENST00000358183.4
CAMTA2



calmodulin binding transcription activator 2



chr2_-_25194963 0.030 ENST00000264711.2
DNAJC27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr21_+_33245548 0.030 ENST00000270112.2
HUNK
hormonally up-regulated Neu-associated kinase
chr21_-_35831880 0.030 ENST00000399289.3
ENST00000432085.1
KCNE1

potassium voltage-gated channel, Isk-related family, member 1

chr15_-_75871589 0.030 ENST00000306726.2
PTPN9
protein tyrosine phosphatase, non-receptor type 9
chr2_-_225450013 0.030 ENST00000264414.4
CUL3
cullin 3
chr5_+_177540444 0.030 ENST00000274605.5
N4BP3
NEDD4 binding protein 3
chr2_-_128643496 0.029 ENST00000272647.5
AMMECR1L
AMMECR1-like
chr10_-_105615164 0.029 ENST00000355946.2
ENST00000369774.4
SH3PXD2A

SH3 and PX domains 2A

chr9_+_114659046 0.028 ENST00000374279.3
UGCG
UDP-glucose ceramide glucosyltransferase
chr1_+_38259540 0.027 ENST00000397631.3
MANEAL
mannosidase, endo-alpha-like
chr4_-_39979576 0.027 ENST00000303538.8
ENST00000503396.1
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr2_-_219433014 0.026 ENST00000418019.1
ENST00000454775.1
ENST00000338465.5
ENST00000415516.1
ENST00000258399.3
USP37




ubiquitin specific peptidase 37




chr1_+_209757051 0.025 ENST00000009105.1
ENST00000423146.1
ENST00000361322.2
CAMK1G


calcium/calmodulin-dependent protein kinase IG


chr11_+_64948665 0.025 ENST00000533820.1
CAPN1
calpain 1, (mu/I) large subunit
chr7_+_100797678 0.025 ENST00000337619.5
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr1_+_214161272 0.024 ENST00000498508.2
ENST00000366958.4
PROX1

prospero homeobox 1

chr6_+_71377473 0.023 ENST00000370452.3
ENST00000316999.5
ENST00000370455.3
SMAP1


small ArfGAP 1


chr2_+_135676381 0.023 ENST00000537343.1
ENST00000295238.6
ENST00000264157.5
CCNT2


cyclin T2


chr1_+_35734562 0.022 ENST00000314607.6
ENST00000373297.2
ZMYM4

zinc finger, MYM-type 4

chr3_+_8775466 0.022 ENST00000343849.2
ENST00000397368.2
CAV3

caveolin 3

chr1_+_52682052 0.022 ENST00000371591.1
ZFYVE9
zinc finger, FYVE domain containing 9
chr19_-_344786 0.022 ENST00000264819.4
MIER2
mesoderm induction early response 1, family member 2
chr16_+_12995468 0.021 ENST00000424107.3
ENST00000558583.1
ENST00000558318.1
SHISA9


shisa family member 9


chr3_-_57199397 0.021 ENST00000296318.7
IL17RD
interleukin 17 receptor D
chr12_-_50101165 0.021 ENST00000352151.5
ENST00000335154.5
ENST00000293590.5
FMNL3


formin-like 3


chr2_-_200322723 0.021 ENST00000417098.1
SATB2
SATB homeobox 2
chr12_+_110437328 0.021 ENST00000261739.4
ANKRD13A
ankyrin repeat domain 13A
chrX_-_108868390 0.020 ENST00000372101.2
KCNE1L
KCNE1-like
chr11_+_65479462 0.020 ENST00000377046.3
ENST00000352980.4
ENST00000341318.4
KAT5


K(lysine) acetyltransferase 5


chr1_+_28696111 0.019 ENST00000373839.3
PHACTR4
phosphatase and actin regulator 4
chr14_+_33408449 0.019 ENST00000346562.2
ENST00000341321.4
ENST00000548645.1
ENST00000356141.4
ENST00000357798.5
NPAS3




neuronal PAS domain protein 3




chr2_-_71062938 0.019 ENST00000410009.3
CD207
CD207 molecule, langerin
chr14_-_23288930 0.018 ENST00000554517.1
ENST00000285850.7
ENST00000397529.2
ENST00000555702.1
SLC7A7



solute carrier family 7 (amino acid transporter light chain, y+L system), member 7




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.1 0.2 GO:0051097 negative regulation of helicase activity(GO:0051097)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.2 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.1 0.2 GO:2000364 regulation of STAT protein import into nucleus(GO:2000364) positive regulation of STAT protein import into nucleus(GO:2000366)
0.1 0.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.2 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.2 GO:0060061 Spemann organizer formation(GO:0060061) dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.0 0.2 GO:1903984 negative regulation of ribosome biogenesis(GO:0090071) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.1 GO:1903410 lysine import(GO:0034226) L-lysine import(GO:0061461) L-lysine import into cell(GO:1903410)
0.0 0.1 GO:0071557 negative regulation of chromatin silencing at rDNA(GO:0061188) histone H3-K27 demethylation(GO:0071557)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.3 GO:0045348 positive regulation of MHC class II biosynthetic process(GO:0045348)
0.0 0.2 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.1 GO:0072720 response to dithiothreitol(GO:0072720)
0.0 0.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990)
0.0 0.3 GO:0035583 sequestering of TGFbeta in extracellular matrix(GO:0035583)
0.0 0.1 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.0 0.4 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.4 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.0 0.2 GO:0071877 regulation of adrenergic receptor signaling pathway(GO:0071877)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.1 GO:0019858 cytosine metabolic process(GO:0019858)
0.0 0.1 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:1904798 positive regulation of core promoter binding(GO:1904798)
0.0 0.1 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0032494 response to peptidoglycan(GO:0032494)
0.0 0.1 GO:1901162 primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:0033274 response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829)
0.0 0.1 GO:0014877 response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.0 0.1 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.1 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259) laminin-11 complex(GO:0043260)
0.0 0.1 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 0.1 GO:0002945 cyclin K-CDK13 complex(GO:0002945)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.1 GO:0034686 integrin alphav-beta8 complex(GO:0034686)
0.0 0.0 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.0 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.1 0.3 GO:0030395 lactose binding(GO:0030395)
0.1 0.2 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.2 GO:0051800 phosphatidylinositol-3,4-bisphosphate 3-phosphatase activity(GO:0051800)
0.0 0.4 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.0 0.1 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.0 0.1 GO:0005289 high-affinity basic amino acid transmembrane transporter activity(GO:0005287) high-affinity arginine transmembrane transporter activity(GO:0005289) high-affinity lysine transmembrane transporter activity(GO:0005292)
0.0 0.4 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.2 GO:0016015 morphogen activity(GO:0016015)
0.0 0.2 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.0 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.1 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.0 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.4 PID_HDAC_CLASSIII_PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_LATE_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.4 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.2 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.2 REACTOME_NRIF_SIGNALS_CELL_DEATH_FROM_THE_NUCLEUS Genes involved in NRIF signals cell death from the nucleus