Motif ID: AGUGCUU

Z-value: 0.572


Mature miRNA associated with seed AGUGCUU:

NamemiRBase Accession
hsa-miR-302c-3p.2
hsa-miR-520f-3p MIMAT0002830



Activity profile for motif AGUGCUU.

activity profile for motif AGUGCUU


Sorted Z-values histogram for motif AGUGCUU

Sorted Z-values for motif AGUGCUU



Network of associatons between targets according to the STRING database.



First level regulatory network of AGUGCUU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_72375167 2.083 ENST00000001146.2
CYP26B1
cytochrome P450, family 26, subfamily B, polypeptide 1
chr12_+_4382917 2.049 ENST00000261254.3
CCND2
cyclin D2
chr17_+_70117153 1.536 ENST00000245479.2
SOX9
SRY (sex determining region Y)-box 9
chr2_-_208030647 1.471 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr20_+_3776371 1.380 ENST00000245960.5
CDC25B
cell division cycle 25B
chr1_-_20812690 1.375 ENST00000375078.3
CAMK2N1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr2_+_174219548 1.340 ENST00000347703.3
ENST00000392567.2
ENST00000306721.3
ENST00000410101.3
ENST00000410019.3
CDCA7




cell division cycle associated 7




chr7_-_41742697 1.024 ENST00000242208.4
INHBA
inhibin, beta A
chr2_-_235405679 0.991 ENST00000390645.2
ARL4C
ADP-ribosylation factor-like 4C
chr21_-_44846999 0.963 ENST00000270162.6
SIK1
salt-inducible kinase 1
chr4_-_111119804 0.952 ENST00000394607.3
ENST00000302274.3
ELOVL6

ELOVL fatty acid elongase 6

chr3_+_47324424 0.862 ENST00000437353.1
ENST00000232766.5
ENST00000455924.2
KLHL18


kelch-like family member 18


chr9_-_99180597 0.860 ENST00000375256.4
ZNF367
zinc finger protein 367
chr14_-_35182994 0.854 ENST00000341223.3
CFL2
cofilin 2 (muscle)
chr12_+_56915713 0.830 ENST00000262031.5
ENST00000552247.2
RBMS2

RNA binding motif, single stranded interacting protein 2

chr15_-_91537723 0.767 ENST00000394249.3
ENST00000559811.1
ENST00000442656.2
ENST00000557905.1
ENST00000361919.3
PRC1




protein regulator of cytokinesis 1




chr1_+_178694300 0.760 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr18_+_21269404 0.723 ENST00000313654.9
LAMA3
laminin, alpha 3
chr9_+_137218362 0.703 ENST00000481739.1
RXRA
retinoid X receptor, alpha
chr2_+_110371905 0.681 ENST00000356454.3
SOWAHC
sosondowah ankyrin repeat domain family member C
chr17_-_79919154 0.673 ENST00000409678.3
NOTUM
notum pectinacetylesterase homolog (Drosophila)
chr1_+_203595903 0.647 ENST00000367218.3
ENST00000367219.3
ENST00000391954.2
ATP2B4


ATPase, Ca++ transporting, plasma membrane 4


chr11_-_119599794 0.636 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr17_+_4736627 0.606 ENST00000355280.6
ENST00000347992.7
MINK1

misshapen-like kinase 1

chr15_+_69706585 0.586 ENST00000559279.1
ENST00000395392.2
KIF23

kinesin family member 23

chr17_+_26662730 0.585 ENST00000226225.2
TNFAIP1
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr1_-_244013384 0.584 ENST00000366539.1
AKT3
v-akt murine thymoma viral oncogene homolog 3
chr11_-_102962929 0.584 ENST00000260247.5
DCUN1D5
DCN1, defective in cullin neddylation 1, domain containing 5
chr16_-_85722530 0.577 ENST00000253462.3
GINS2
GINS complex subunit 2 (Psf2 homolog)
chr7_-_28220354 0.568 ENST00000283928.5
JAZF1
JAZF zinc finger 1
chr15_+_38544476 0.561 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr12_-_108154925 0.543 ENST00000228437.5
PRDM4
PR domain containing 4
chr8_+_42752053 0.536 ENST00000307602.4
HOOK3
hook microtubule-tethering protein 3
chr3_-_149093499 0.532 ENST00000472441.1
TM4SF1
transmembrane 4 L six family member 1
chr9_-_35732362 0.525 ENST00000314888.9
ENST00000540444.1
TLN1

talin 1

chr2_+_173940442 0.522 ENST00000409176.2
ENST00000338983.3
ENST00000431503.2
MLTK


Mitogen-activated protein kinase kinase kinase MLT


chr3_-_45017609 0.513 ENST00000342790.4
ENST00000424952.2
ENST00000296127.3
ENST00000455235.1
ZDHHC3



zinc finger, DHHC-type containing 3



chr3_-_87040233 0.512 ENST00000398399.2
VGLL3
vestigial like 3 (Drosophila)
chr1_-_53793584 0.507 ENST00000354412.3
ENST00000347547.2
ENST00000306052.6
LRP8


low density lipoprotein receptor-related protein 8, apolipoprotein e receptor


chr3_-_48229846 0.503 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
CDC25A


cell division cycle 25A


chr1_+_214776516 0.503 ENST00000366955.3
CENPF
centromere protein F, 350/400kDa
chr9_+_2621798 0.503 ENST00000382100.3
VLDLR
very low density lipoprotein receptor
chr22_-_22221900 0.498 ENST00000215832.6
ENST00000398822.3
MAPK1

mitogen-activated protein kinase 1

chr2_-_43453734 0.495 ENST00000282388.3
ZFP36L2
ZFP36 ring finger protein-like 2
chr22_+_38302285 0.489 ENST00000215957.6
MICALL1
MICAL-like 1
chr17_-_17875688 0.479 ENST00000379504.3
ENST00000318094.10
ENST00000540946.1
ENST00000542206.1
ENST00000395739.4
ENST00000581396.1
ENST00000535933.1
ENST00000579586.1
TOM1L2







target of myb1-like 2 (chicken)







chr9_-_95432536 0.477 ENST00000287996.3
IPPK
inositol 1,3,4,5,6-pentakisphosphate 2-kinase
chr8_-_105601134 0.469 ENST00000276654.5
ENST00000424843.2
LRP12

low density lipoprotein receptor-related protein 12

chr11_+_119076745 0.456 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr1_+_178062855 0.428 ENST00000448150.3
RASAL2
RAS protein activator like 2
chr10_+_98741041 0.418 ENST00000286067.2
C10orf12
chromosome 10 open reading frame 12
chr5_-_44388899 0.406 ENST00000264664.4
FGF10
fibroblast growth factor 10
chr9_+_128509624 0.405 ENST00000342287.5
ENST00000373487.4
PBX3

pre-B-cell leukemia homeobox 3

chr6_+_41040678 0.404 ENST00000341376.6
ENST00000353205.5
NFYA

nuclear transcription factor Y, alpha

chr6_-_42419649 0.401 ENST00000372922.4
ENST00000541110.1
ENST00000372917.4
TRERF1


transcriptional regulating factor 1


chr11_-_85780086 0.392 ENST00000532317.1
ENST00000528256.1
ENST00000526033.1
PICALM


phosphatidylinositol binding clathrin assembly protein


chr1_-_38325256 0.390 ENST00000373036.4
MTF1
metal-regulatory transcription factor 1
chr1_-_85156216 0.382 ENST00000342203.3
ENST00000370612.4
SSX2IP

synovial sarcoma, X breakpoint 2 interacting protein

chr11_+_69455855 0.379 ENST00000227507.2
ENST00000536559.1
CCND1

cyclin D1

chr1_-_230561475 0.371 ENST00000391860.1
PGBD5
piggyBac transposable element derived 5
chr20_+_1875110 0.366 ENST00000400068.3
SIRPA
signal-regulatory protein alpha
chr3_-_197476560 0.363 ENST00000273582.5
KIAA0226
KIAA0226
chr1_+_25071848 0.362 ENST00000374379.4
CLIC4
chloride intracellular channel 4
chr13_-_79177673 0.358 ENST00000377208.5
POU4F1
POU class 4 homeobox 1
chr19_-_2050852 0.357 ENST00000541165.1
ENST00000591601.1
MKNK2

MAP kinase interacting serine/threonine kinase 2

chrX_+_41192595 0.353 ENST00000399959.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr13_+_52158610 0.352 ENST00000298125.5
WDFY2
WD repeat and FYVE domain containing 2
chr10_+_43633914 0.352 ENST00000374466.3
ENST00000374464.1
CSGALNACT2

chondroitin sulfate N-acetylgalactosaminyltransferase 2

chr4_-_41216619 0.350 ENST00000508676.1
ENST00000506352.1
ENST00000295974.8
APBB2


amyloid beta (A4) precursor protein-binding, family B, member 2


chr15_-_73661605 0.350 ENST00000261917.3
HCN4
hyperpolarization activated cyclic nucleotide-gated potassium channel 4
chr13_-_25746416 0.349 ENST00000515384.1
ENST00000357816.2
AMER2

APC membrane recruitment protein 2

chrX_-_46618490 0.349 ENST00000328306.4
SLC9A7
solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
chr11_-_78052923 0.349 ENST00000340149.2
GAB2
GRB2-associated binding protein 2
chr3_-_69435224 0.346 ENST00000398540.3
FRMD4B
FERM domain containing 4B
chrX_+_28605516 0.344 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr2_+_26256938 0.341 ENST00000264710.4
RAB10
RAB10, member RAS oncogene family
chr8_-_60031762 0.340 ENST00000361421.1
TOX
thymocyte selection-associated high mobility group box
chr2_+_26568965 0.330 ENST00000260585.7
ENST00000447170.1
EPT1

ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)

chr6_+_158244223 0.328 ENST00000392185.3
SNX9
sorting nexin 9
chr2_+_118846008 0.327 ENST00000245787.4
INSIG2
insulin induced gene 2
chr17_-_76356148 0.318 ENST00000587578.1
ENST00000330871.2
SOCS3

suppressor of cytokine signaling 3

chr22_-_36236265 0.317 ENST00000414461.2
ENST00000416721.2
ENST00000449924.2
ENST00000262829.7
ENST00000397305.3
RBFOX2




RNA binding protein, fox-1 homolog (C. elegans) 2




chr9_-_110251836 0.314 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr3_-_122233723 0.312 ENST00000493510.1
ENST00000344337.6
ENST00000476916.1
ENST00000465882.1
KPNA1



karyopherin alpha 1 (importin alpha 5)



chr7_+_28452130 0.312 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr20_+_56884752 0.310 ENST00000244040.3
RAB22A
RAB22A, member RAS oncogene family
chr1_+_213123915 0.309 ENST00000366968.4
ENST00000490792.1
VASH2

vasohibin 2

chr3_+_14860469 0.306 ENST00000285046.5
FGD5
FYVE, RhoGEF and PH domain containing 5
chr11_+_122526383 0.304 ENST00000284273.5
UBASH3B
ubiquitin associated and SH3 domain containing B
chr8_-_124408652 0.303 ENST00000287394.5
ATAD2
ATPase family, AAA domain containing 2
chr6_-_108395907 0.302 ENST00000193322.3
OSTM1
osteopetrosis associated transmembrane protein 1
chr4_-_114900831 0.298 ENST00000315366.7
ARSJ
arylsulfatase family, member J
chr17_+_38333263 0.288 ENST00000456989.2
ENST00000543876.1
ENST00000544503.1
ENST00000264644.6
ENST00000538884.1
RAPGEFL1




Rap guanine nucleotide exchange factor (GEF)-like 1




chr12_-_54779511 0.276 ENST00000551109.1
ENST00000546970.1
ZNF385A

zinc finger protein 385A

chrX_+_16737718 0.263 ENST00000380155.3
SYAP1
synapse associated protein 1
chr7_+_138916231 0.262 ENST00000473989.3
ENST00000288561.8
UBN2

ubinuclein 2

chr11_+_64126614 0.260 ENST00000528057.1
ENST00000334205.4
ENST00000294261.4
RPS6KA4


ribosomal protein S6 kinase, 90kDa, polypeptide 4


chr18_-_51751132 0.257 ENST00000256429.3
MBD2
methyl-CpG binding domain protein 2
chr12_+_32655048 0.252 ENST00000427716.2
ENST00000266482.3
FGD4

FYVE, RhoGEF and PH domain containing 4

chr3_-_164913777 0.247 ENST00000475390.1
SLITRK3
SLIT and NTRK-like family, member 3
chr17_-_5138099 0.243 ENST00000571800.1
ENST00000574081.1
ENST00000399600.4
ENST00000574297.1
SCIMP



SLP adaptor and CSK interacting membrane protein



chr1_+_78245303 0.240 ENST00000370791.3
ENST00000443751.2
FAM73A

family with sequence similarity 73, member A

chr11_+_128563652 0.238 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr5_-_141704566 0.236 ENST00000344120.4
ENST00000434127.2
SPRY4

sprouty homolog 4 (Drosophila)

chr12_+_20522179 0.234 ENST00000359062.3
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr8_-_141645645 0.229 ENST00000519980.1
ENST00000220592.5
AGO2

argonaute RISC catalytic component 2

chr1_+_12040238 0.228 ENST00000444836.1
ENST00000235329.5
MFN2

mitofusin 2

chr3_+_126707437 0.226 ENST00000393409.2
ENST00000251772.4
PLXNA1

plexin A1

chr2_+_11674213 0.225 ENST00000381486.2
GREB1
growth regulation by estrogen in breast cancer 1
chr5_+_176560742 0.224 ENST00000439151.2
NSD1
nuclear receptor binding SET domain protein 1
chr1_+_7831323 0.219 ENST00000054666.6
VAMP3
vesicle-associated membrane protein 3
chr8_+_102504651 0.217 ENST00000251808.3
ENST00000521085.1
GRHL2

grainyhead-like 2 (Drosophila)

chr2_+_9346892 0.217 ENST00000281419.3
ENST00000315273.4
ASAP2

ArfGAP with SH3 domain, ankyrin repeat and PH domain 2

chr6_+_45389893 0.214 ENST00000371432.3
RUNX2
runt-related transcription factor 2
chr5_-_171433819 0.211 ENST00000296933.6
FBXW11
F-box and WD repeat domain containing 11
chr11_+_32914579 0.209 ENST00000399302.2
QSER1
glutamine and serine rich 1
chrX_+_24072833 0.209 ENST00000253039.4
EIF2S3
eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa
chr1_-_70671216 0.207 ENST00000370952.3
LRRC40
leucine rich repeat containing 40
chr2_+_103236004 0.205 ENST00000233969.2
SLC9A2
solute carrier family 9, subfamily A (NHE2, cation proton antiporter 2), member 2
chr10_-_23003460 0.205 ENST00000376573.4
PIP4K2A
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr5_+_170814803 0.205 ENST00000521672.1
ENST00000351986.6
ENST00000393820.2
ENST00000523622.1
NPM1



nucleophosmin (nucleolar phosphoprotein B23, numatrin)



chr9_+_116638562 0.203 ENST00000374126.5
ENST00000288466.7
ZNF618

zinc finger protein 618

chr4_+_156588350 0.203 ENST00000296518.7
GUCY1A3
guanylate cyclase 1, soluble, alpha 3
chr3_+_23244780 0.202 ENST00000396703.1
UBE2E2
ubiquitin-conjugating enzyme E2E 2
chr17_+_5185552 0.201 ENST00000262477.6
ENST00000408982.2
ENST00000575991.1
ENST00000537505.1
ENST00000546142.2
RABEP1




rabaptin, RAB GTPase binding effector protein 1




chr17_+_40761660 0.201 ENST00000251413.3
ENST00000591509.1
TUBG1

tubulin, gamma 1

chr1_+_200708671 0.201 ENST00000358823.2
CAMSAP2
calmodulin regulated spectrin-associated protein family, member 2
chr10_+_94050913 0.201 ENST00000358935.2
MARCH5
membrane-associated ring finger (C3HC4) 5
chrX_-_70288234 0.200 ENST00000276105.3
ENST00000374274.3
SNX12

sorting nexin 12

chr12_-_76953284 0.194 ENST00000547544.1
ENST00000393249.2
OSBPL8

oxysterol binding protein-like 8

chr20_+_46130601 0.192 ENST00000341724.6
NCOA3
nuclear receptor coactivator 3
chr2_+_178257372 0.190 ENST00000264167.4
ENST00000409888.1
AGPS

alkylglycerone phosphate synthase

chr9_-_107690420 0.188 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1


ATP-binding cassette, sub-family A (ABC1), member 1


chr16_+_24741013 0.187 ENST00000315183.7
ENST00000395799.3
TNRC6A

trinucleotide repeat containing 6A

chr10_-_75910789 0.185 ENST00000355264.4
AP3M1
adaptor-related protein complex 3, mu 1 subunit
chr19_+_39138271 0.184 ENST00000252699.2
ACTN4
actinin, alpha 4
chr3_-_183735731 0.182 ENST00000334444.6
ABCC5
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr1_-_102462565 0.180 ENST00000370103.4
OLFM3
olfactomedin 3
chr3_+_132136331 0.180 ENST00000260818.6
DNAJC13
DnaJ (Hsp40) homolog, subfamily C, member 13
chr17_+_38375574 0.180 ENST00000323571.4
ENST00000585043.1
ENST00000394103.3
ENST00000536600.1
WIPF2



WAS/WASL interacting protein family, member 2



chr14_+_67826709 0.179 ENST00000256383.4
EIF2S1
eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
chr14_-_47812321 0.178 ENST00000357362.3
ENST00000486952.2
ENST00000426342.1
MDGA2


MAM domain containing glycosylphosphatidylinositol anchor 2


chr15_+_66161871 0.178 ENST00000569896.1
RAB11A
RAB11A, member RAS oncogene family
chr2_+_185463093 0.177 ENST00000302277.6
ZNF804A
zinc finger protein 804A
chr6_+_35310312 0.174 ENST00000448077.2
ENST00000360694.3
ENST00000418635.2
ENST00000444397.1
PPARD



peroxisome proliferator-activated receptor delta



chr1_-_150552006 0.171 ENST00000307940.3
ENST00000369026.2
MCL1

myeloid cell leukemia sequence 1 (BCL2-related)

chr12_+_88536067 0.170 ENST00000549011.1
ENST00000266712.6
ENST00000551088.1
TMTC3


transmembrane and tetratricopeptide repeat containing 3


chr7_+_100136811 0.163 ENST00000300176.4
ENST00000262935.4
AGFG2

ArfGAP with FG repeats 2

chrX_-_30885319 0.162 ENST00000378933.1
TAB3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr1_+_2985760 0.158 ENST00000378391.2
ENST00000514189.1
ENST00000270722.5
PRDM16


PR domain containing 16


chr14_+_50359773 0.158 ENST00000298316.5
ARF6
ADP-ribosylation factor 6
chrX_+_24483338 0.158 ENST00000379162.4
ENST00000441463.2
PDK3

pyruvate dehydrogenase kinase, isozyme 3

chr16_+_25703274 0.157 ENST00000331351.5
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr2_-_183903133 0.155 ENST00000361354.4
NCKAP1
NCK-associated protein 1
chr12_-_96184533 0.151 ENST00000343702.4
ENST00000344911.4
NTN4

netrin 4

chr10_-_120514720 0.148 ENST00000369151.3
ENST00000340214.4
CACUL1

CDK2-associated, cullin domain 1

chr4_+_99916765 0.148 ENST00000296411.6
METAP1
methionyl aminopeptidase 1
chr3_+_85008089 0.146 ENST00000383699.3
CADM2
cell adhesion molecule 2
chr3_+_14989076 0.146 ENST00000413118.1
ENST00000425241.1
NR2C2

nuclear receptor subfamily 2, group C, member 2

chr3_-_176914238 0.145 ENST00000430069.1
ENST00000428970.1
TBL1XR1

transducin (beta)-like 1 X-linked receptor 1

chr3_-_56835967 0.145 ENST00000495373.1
ENST00000296315.3
ARHGEF3

Rho guanine nucleotide exchange factor (GEF) 3

chr18_-_18691739 0.142 ENST00000399799.2
ROCK1
Rho-associated, coiled-coil containing protein kinase 1
chr3_+_37493610 0.137 ENST00000264741.5
ITGA9
integrin, alpha 9
chr2_+_99953816 0.137 ENST00000289371.6
EIF5B
eukaryotic translation initiation factor 5B
chrX_-_20134990 0.133 ENST00000379651.3
ENST00000443379.3
ENST00000379643.5
MAP7D2


MAP7 domain containing 2


chr3_+_30648066 0.131 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr8_+_106330920 0.131 ENST00000407775.2
ZFPM2
zinc finger protein, FOG family member 2
chr1_+_184356188 0.129 ENST00000235307.6
C1orf21
chromosome 1 open reading frame 21
chr6_+_24667257 0.128 ENST00000537591.1
ENST00000230048.4
ACOT13

acyl-CoA thioesterase 13

chr20_-_41818373 0.122 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
PTPRT



protein tyrosine phosphatase, receptor type, T



chr7_-_123389104 0.121 ENST00000223023.4
WASL
Wiskott-Aldrich syndrome-like
chr3_+_152017181 0.120 ENST00000498502.1
ENST00000324196.5
ENST00000545754.1
ENST00000357472.3
MBNL1



muscleblind-like splicing regulator 1



chr14_-_23504087 0.119 ENST00000493471.2
ENST00000460922.2
PSMB5

proteasome (prosome, macropain) subunit, beta type, 5

chr8_-_119634141 0.118 ENST00000409003.4
ENST00000526328.1
ENST00000314727.4
ENST00000526765.1
SAMD12



sterile alpha motif domain containing 12



chr12_-_31744031 0.115 ENST00000389082.5
DENND5B
DENN/MADD domain containing 5B
chr14_-_75593708 0.115 ENST00000557673.1
ENST00000238616.5
NEK9

NIMA-related kinase 9

chr17_-_62658186 0.115 ENST00000262435.9
SMURF2
SMAD specific E3 ubiquitin protein ligase 2
chr22_+_29469012 0.110 ENST00000400335.4
ENST00000400338.2
KREMEN1

kringle containing transmembrane protein 1

chr19_+_33463127 0.110 ENST00000589646.1
ENST00000588258.1
ENST00000590179.1
C19orf40


chromosome 19 open reading frame 40


chr3_+_119013185 0.109 ENST00000264245.4
ARHGAP31
Rho GTPase activating protein 31
chr6_+_152011628 0.109 ENST00000404742.1
ENST00000440973.1
ESR1

estrogen receptor 1

chr10_+_112631547 0.108 ENST00000280154.7
ENST00000393104.2
PDCD4

programmed cell death 4 (neoplastic transformation inhibitor)

chr8_+_9009202 0.108 ENST00000518496.1
RP11-10A14.4
Uncharacterized protein
chr15_-_56535464 0.103 ENST00000559447.2
ENST00000422057.1
ENST00000317318.6
ENST00000423270.1
RFX7



regulatory factor X, 7



chr20_-_9819479 0.103 ENST00000378423.1
ENST00000353224.5
PAK7

p21 protein (Cdc42/Rac)-activated kinase 7

chr3_-_179754706 0.102 ENST00000465751.1
ENST00000467460.1
PEX5L

peroxisomal biogenesis factor 5-like

chr7_+_129074266 0.100 ENST00000249344.2
ENST00000435494.2
STRIP2

striatin interacting protein 2

chr16_+_7382745 0.098 ENST00000436368.2
ENST00000311745.5
ENST00000355637.4
ENST00000340209.4
RBFOX1



RNA binding protein, fox-1 homolog (C. elegans) 1



chr2_-_164592497 0.097 ENST00000333129.3
ENST00000409634.1
FIGN

fidgetin

chr4_-_102268628 0.097 ENST00000323055.6
ENST00000512215.1
ENST00000394854.3
PPP3CA


protein phosphatase 3, catalytic subunit, alpha isozyme


chr4_+_74606223 0.096 ENST00000307407.3
ENST00000401931.1
IL8

interleukin 8

chr2_-_166651191 0.096 ENST00000392701.3
GALNT3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3)
chr18_-_67624160 0.094 ENST00000581982.1
ENST00000280200.4
CD226

CD226 molecule

chr10_+_78078088 0.094 ENST00000496424.2
C10orf11
chromosome 10 open reading frame 11
chr9_+_5510492 0.093 ENST00000397745.2
PDCD1LG2
programmed cell death 1 ligand 2
chr6_-_157744531 0.092 ENST00000400788.4
ENST00000367144.4
TMEM242

transmembrane protein 242

chr9_-_16870704 0.089 ENST00000380672.4
ENST00000380667.2
ENST00000380666.2
ENST00000486514.1
BNC2



basonuclin 2



chr13_+_39612442 0.089 ENST00000470258.1
ENST00000379600.3
NHLRC3

NHL repeat containing 3

chr17_+_47074758 0.087 ENST00000290341.3
IGF2BP1
insulin-like growth factor 2 mRNA binding protein 1
chr11_-_110167352 0.087 ENST00000533991.1
ENST00000528498.1
ENST00000405097.1
ENST00000528900.1
ENST00000530301.1
ENST00000343115.4
RDX





radixin






Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:2001037 tongue muscle cell differentiation(GO:0035981) positive regulation of skeletal muscle fiber differentiation(GO:1902811) regulation of tongue muscle cell differentiation(GO:2001035) positive regulation of tongue muscle cell differentiation(GO:2001037)
0.5 1.5 GO:0060516 primary prostatic bud elongation(GO:0060516) renal vesicle induction(GO:0072034)
0.3 1.0 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.2 0.7 GO:0045994 positive regulation of translational initiation by iron(GO:0045994)
0.2 0.6 GO:0033242 regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283)
0.2 1.0 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.2 0.8 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.2 0.2 GO:1902954 regulation of early endosome to recycling endosome transport(GO:1902954)
0.2 0.5 GO:0019858 cytosine metabolic process(GO:0019858)
0.1 0.6 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 0.4 GO:0071335 proximal/distal axis specification(GO:0009946) bronchiole development(GO:0060435) bud outgrowth involved in lung branching(GO:0060447) submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 1.0 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 1.4 GO:0007144 female meiosis I(GO:0007144)
0.1 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.4 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 0.3 GO:0097051 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.3 GO:0060988 lipid tube assembly(GO:0060988)
0.1 1.0 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.3 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.6 GO:0071321 cellular response to cGMP(GO:0071321)
0.1 0.6 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.1 0.4 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.1 2.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.1 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.2 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.6 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.2 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.5 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.2 GO:1990737 response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.1 0.7 GO:0042159 lipoprotein catabolic process(GO:0042159)
0.1 0.4 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.1 0.3 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.5 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.9 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.2 GO:0060969 negative regulation of chromatin silencing(GO:0031936) negative regulation of gene silencing(GO:0060969)
0.1 0.8 GO:0000022 mitotic spindle elongation(GO:0000022)
0.0 0.2 GO:0015917 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.2 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.1 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.0 0.1 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.0 0.2 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.4 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.2 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.4 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.2 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.1 GO:1904760 myofibroblast differentiation(GO:0036446) cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939) epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940) regulation of myofibroblast differentiation(GO:1904760)
0.0 0.2 GO:0090625 mRNA cleavage involved in gene silencing by siRNA(GO:0090625)
0.0 0.3 GO:0060318 regulation of definitive erythrocyte differentiation(GO:0010724) definitive erythrocyte differentiation(GO:0060318)
0.0 0.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.7 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.6 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.4 GO:0070141 response to UV-A(GO:0070141)
0.0 0.3 GO:0097105 presynaptic membrane assembly(GO:0097105)
0.0 0.2 GO:0052551 response to defense-related nitric oxide production by other organism involved in symbiotic interaction(GO:0052551) response to defense-related host nitric oxide production(GO:0052565)
0.0 0.1 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.0 0.1 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0030201 heparan sulfate proteoglycan metabolic process(GO:0030201)
0.0 0.2 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.2 GO:0035624 receptor transactivation(GO:0035624)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.3 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.6 GO:0045116 protein neddylation(GO:0045116)
0.0 0.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.2 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
0.0 0.1 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 1.0 GO:0032456 endocytic recycling(GO:0032456)
0.0 0.6 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.0 GO:0072179 nephric duct formation(GO:0072179)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.6 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.1 GO:2000272 negative regulation of receptor activity(GO:2000272)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 0.2 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.3 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.0 0.2 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.1 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.4 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.3 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.0 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.4 GO:0071243 cellular response to arsenic-containing substance(GO:0071243)
0.0 0.3 GO:0060716 labyrinthine layer blood vessel development(GO:0060716)
0.0 0.2 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 0.2 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.5 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.3 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 0.0 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.0 GO:0097045 phosphatidylserine exposure on blood platelet(GO:0097045)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.0 GO:0098907 protein localization to M-band(GO:0036309) regulation of SA node cell action potential(GO:0098907)
0.0 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.3 GO:0007398 ectoderm development(GO:0007398)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.4 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.3 GO:0006309 apoptotic DNA fragmentation(GO:0006309)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.3 1.0 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.6 GO:0000811 GINS complex(GO:0000811)
0.1 0.4 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.6 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.7 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 0.4 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.8 GO:0070938 contractile ring(GO:0070938)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.5 GO:0016600 flotillin complex(GO:0016600)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.4 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.7 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.2 GO:0005827 polar microtubule(GO:0005827)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.6 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.2 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.2 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.5 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.4 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 1.1 GO:0005901 caveola(GO:0005901)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.7 GO:0000118 histone deacetylase complex(GO:0000118)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.4 2.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.3 1.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.3 1.0 GO:0038025 reelin receptor activity(GO:0038025)
0.2 0.6 GO:0036487 nitric-oxide synthase inhibitor activity(GO:0036487)
0.2 0.6 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.7 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.5 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 0.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 1.0 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.4 GO:0047237 glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity(GO:0047237)
0.1 0.2 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.2 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 1.0 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.5 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.6 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.4 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.6 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.6 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.4 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.5 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.3 GO:0003696 satellite DNA binding(GO:0003696)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 1.0 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.6 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.0 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.2 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 2.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.4 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.6 GO:0004629 phospholipase C activity(GO:0004629)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0051434 protein channel activity(GO:0015266) BH3 domain binding(GO:0051434)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.2 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.7 GO:0019894 kinesin binding(GO:0019894)
0.0 0.4 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.0 GO:0015375 glycine:sodium symporter activity(GO:0015375)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.1 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 2.5 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 1.4 PID_REELIN_PATHWAY Reelin signaling pathway
0.0 0.7 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.2 PID_ALK1_PATHWAY ALK1 signaling events
0.0 1.2 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 1.1 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 1.3 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.6 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.7 ST_P38_MAPK_PATHWAY p38 MAPK Pathway
0.0 0.8 PID_PLK1_PATHWAY PLK1 signaling events
0.0 1.1 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 1.7 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.2 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.3 PID_PI3KCI_AKT_PATHWAY Class I PI3K signaling events mediated by Akt
0.0 0.6 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.5 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.3 PID_EPO_PATHWAY EPO signaling pathway
0.0 0.6 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones
0.1 1.9 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 0.6 REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.5 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 0.8 REACTOME_IL_6_SIGNALING Genes involved in Interleukin-6 signaling
0.0 2.4 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.8 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 1.0 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 1.0 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.6 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.0 2.1 REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.0 0.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME_FGFR1_LIGAND_BINDING_AND_ACTIVATION Genes involved in FGFR1 ligand binding and activation
0.0 0.2 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.3 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME_APOPTOSIS_INDUCED_DNA_FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME_RECRUITMENT_OF_NUMA_TO_MITOTIC_CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.3 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME_IL_RECEPTOR_SHC_SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME_NEPHRIN_INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME_CHONDROITIN_SULFATE_BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis