Motif ID: ARNT

Z-value: 1.239


Transcription factors associated with ARNT:

Gene SymbolEntrez IDGene Name
ARNT ENSG00000143437.16 ARNT

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ARNThg19_v2_chr1_-_150849174_150849200,
hg19_v2_chr1_-_150849047_150849085
0.795.3e-06Click!


Activity profile for motif ARNT.

activity profile for motif ARNT


Sorted Z-values histogram for motif ARNT

Sorted Z-values for motif ARNT



Network of associatons between targets according to the STRING database.



First level regulatory network of ARNT

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_+_173420697 6.302 ENST00000282077.3
ENST00000392571.2
ENST00000410055.1
PDK1


pyruvate dehydrogenase kinase, isozyme 1


chr1_-_113498616 4.599 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1


solute carrier family 16 (monocarboxylate transporter), member 1


chr6_+_151561506 3.803 ENST00000253332.1
AKAP12
A kinase (PRKA) anchor protein 12
chr18_-_33077556 3.801 ENST00000589273.1
ENST00000586489.1
INO80C

INO80 complex subunit C

chr15_+_40453204 3.713 ENST00000287598.6
ENST00000412359.3
BUB1B

BUB1 mitotic checkpoint serine/threonine kinase B

chr1_-_113498943 3.638 ENST00000369626.3
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr7_-_128045984 3.603 ENST00000470772.1
ENST00000480861.1
ENST00000496200.1
IMPDH1


IMP (inosine 5'-monophosphate) dehydrogenase 1


chrX_+_77359671 3.442 ENST00000373316.4
PGK1
phosphoglycerate kinase 1
chrX_+_69509927 3.315 ENST00000374403.3
KIF4A
kinesin family member 4A
chr15_+_45722727 3.291 ENST00000396650.2
ENST00000558435.1
ENST00000344300.3
C15orf48


chromosome 15 open reading frame 48


chr11_+_72929319 3.230 ENST00000393597.2
ENST00000311131.2
P2RY2

purinergic receptor P2Y, G-protein coupled, 2

chr22_+_40390930 3.223 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr11_+_72929402 3.139 ENST00000393596.2
P2RY2
purinergic receptor P2Y, G-protein coupled, 2
chr2_+_192543153 3.066 ENST00000425611.2
NABP1
nucleic acid binding protein 1
chr19_+_1407733 3.045 ENST00000592453.1
DAZAP1
DAZ associated protein 1
chr3_+_5020801 3.016 ENST00000256495.3
BHLHE40
basic helix-loop-helix family, member e40
chr11_-_6341724 3.013 ENST00000530979.1
PRKCDBP
protein kinase C, delta binding protein
chr9_-_123638633 2.918 ENST00000456291.1
PHF19
PHD finger protein 19
chr9_+_35673853 2.889 ENST00000378357.4
CA9
carbonic anhydrase IX
chr9_-_123639304 2.831 ENST00000436309.1
PHF19
PHD finger protein 19
chr11_-_66725837 2.736 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC



pyruvate carboxylase



chr6_+_151561085 2.714 ENST00000402676.2
AKAP12
A kinase (PRKA) anchor protein 12
chr2_-_235405168 2.675 ENST00000339728.3
ARL4C
ADP-ribosylation factor-like 4C
chrX_+_77359726 2.595 ENST00000442431.1
PGK1
phosphoglycerate kinase 1
chr19_-_45909585 2.545 ENST00000593226.1
ENST00000418234.2
PPP1R13L

protein phosphatase 1, regulatory subunit 13 like

chr6_+_43739697 2.532 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr1_-_26232951 2.427 ENST00000426559.2
ENST00000455785.2
STMN1

stathmin 1

chr3_+_100211412 2.367 ENST00000323523.4
ENST00000403410.1
ENST00000449609.1
TMEM45A


transmembrane protein 45A


chr18_+_33877654 2.336 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
FHOD3



formin homology 2 domain containing 3



chr1_-_26232522 2.259 ENST00000399728.1
STMN1
stathmin 1
chr9_-_123639445 2.126 ENST00000312189.6
PHF19
PHD finger protein 19
chr18_-_33077942 2.045 ENST00000334598.7
INO80C
INO80 complex subunit C
chr6_-_144329531 2.035 ENST00000429150.1
ENST00000392309.1
ENST00000416623.1
ENST00000392307.1
PLAGL1



pleiomorphic adenoma gene-like 1



chr1_+_65613852 1.900 ENST00000327299.7
AK4
adenylate kinase 4
chr5_+_38846101 1.806 ENST00000274276.3
OSMR
oncostatin M receptor
chr1_-_26233423 1.709 ENST00000357865.2
STMN1
stathmin 1
chr7_-_100860851 1.708 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr11_-_64646086 1.664 ENST00000320631.3
EHD1
EH-domain containing 1
chr3_-_149688896 1.664 ENST00000239940.7
PFN2
profilin 2
chr6_+_34204642 1.642 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chr7_-_27135591 1.611 ENST00000343060.4
ENST00000355633.5
HOXA1

homeobox A1

chr10_-_133795416 1.605 ENST00000540159.1
ENST00000368636.4
BNIP3

BCL2/adenovirus E1B 19kDa interacting protein 3

chr3_+_122785895 1.569 ENST00000316218.7
PDIA5
protein disulfide isomerase family A, member 5
chr12_+_15475331 1.550 ENST00000281171.4
PTPRO
protein tyrosine phosphatase, receptor type, O
chr5_-_131563501 1.527 ENST00000401867.1
ENST00000379086.1
ENST00000418055.1
ENST00000453286.1
ENST00000166534.4
P4HA2




prolyl 4-hydroxylase, alpha polypeptide II




chr10_-_121356518 1.523 ENST00000369092.4
TIAL1
TIA1 cytotoxic granule-associated RNA binding protein-like 1
chr6_-_31869769 1.512 ENST00000375527.2
ZBTB12
zinc finger and BTB domain containing 12
chr2_-_96781984 1.511 ENST00000409345.3
ADRA2B
adrenoceptor alpha 2B
chr4_-_103266355 1.505 ENST00000424970.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr17_-_41623716 1.505 ENST00000319349.5
ETV4
ets variant 4
chr6_+_151187074 1.501 ENST00000367308.4
MTHFD1L
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr10_+_120967072 1.501 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr10_+_101419187 1.490 ENST00000370489.4
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chrX_-_51239425 1.483 ENST00000375992.3
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr17_+_17942684 1.472 ENST00000376345.3
GID4
GID complex subunit 4
chr17_-_8059638 1.453 ENST00000584202.1
ENST00000354903.5
ENST00000577253.1
PER1


period circadian clock 1


chr10_+_112257596 1.419 ENST00000369583.3
DUSP5
dual specificity phosphatase 5
chr2_+_75061108 1.409 ENST00000290573.2
HK2
hexokinase 2
chr1_-_111991850 1.394 ENST00000411751.2
WDR77
WD repeat domain 77
chr4_-_103266626 1.392 ENST00000356736.4
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr16_-_4588762 1.389 ENST00000562334.1
ENST00000562579.1
ENST00000567695.1
ENST00000563507.1
CDIP1



cell death-inducing p53 target 1



chr11_-_64014379 1.389 ENST00000309318.3
PPP1R14B
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr5_+_38845960 1.371 ENST00000502536.1
OSMR
oncostatin M receptor
chr18_+_56530794 1.356 ENST00000590285.1
ENST00000586085.1
ENST00000589288.1
ZNF532


zinc finger protein 532


chr14_-_53162361 1.355 ENST00000395686.3
ERO1L
ERO1-like (S. cerevisiae)
chr3_-_156272924 1.351 ENST00000467789.1
ENST00000265044.2
SSR3

signal sequence receptor, gamma (translocon-associated protein gamma)

chr21_-_32931290 1.321 ENST00000286827.3
TIAM1
T-cell lymphoma invasion and metastasis 1
chr19_-_44285401 1.313 ENST00000262888.3
KCNN4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr20_-_44540686 1.303 ENST00000477313.1
ENST00000542937.1
ENST00000372431.3
ENST00000354050.4
ENST00000420868.2
PLTP




phospholipid transfer protein




chr20_-_6103666 1.279 ENST00000536936.1
FERMT1
fermitin family member 1
chr3_-_156272872 1.272 ENST00000476217.1
SSR3
signal sequence receptor, gamma (translocon-associated protein gamma)
chr9_-_94186131 1.270 ENST00000297689.3
NFIL3
nuclear factor, interleukin 3 regulated
chr7_+_26331541 1.267 ENST00000416246.1
ENST00000338523.4
ENST00000412416.1
SNX10


sorting nexin 10


chr11_+_62623512 1.264 ENST00000377892.1
SLC3A2
solute carrier family 3 (amino acid transporter heavy chain), member 2
chr3_-_145878954 1.260 ENST00000282903.5
ENST00000360060.3
PLOD2

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2

chr5_-_114961673 1.252 ENST00000333314.3
TMED7-TICAM2
TMED7-TICAM2 readthrough
chr6_+_151187615 1.251 ENST00000441122.1
ENST00000423867.1
MTHFD1L

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

chr7_+_65540853 1.250 ENST00000380839.4
ENST00000395332.3
ENST00000362000.5
ENST00000395331.3
ASL



argininosuccinate lyase



chr10_-_101945771 1.245 ENST00000370408.2
ENST00000407654.3
ERLIN1

ER lipid raft associated 1

chr1_+_44445549 1.241 ENST00000356836.6
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr7_-_100425112 1.224 ENST00000358173.3
EPHB4
EPH receptor B4
chr9_+_112542572 1.210 ENST00000374530.3
PALM2-AKAP2
PALM2-AKAP2 readthrough
chr5_-_171881362 1.204 ENST00000519643.1
SH3PXD2B
SH3 and PX domains 2B
chr7_+_65540780 1.188 ENST00000304874.9
ASL
argininosuccinate lyase
chr1_+_209848749 1.187 ENST00000367029.4
G0S2
G0/G1switch 2
chr10_-_76995675 1.172 ENST00000469299.1
COMTD1
catechol-O-methyltransferase domain containing 1
chrX_-_41782683 1.169 ENST00000378163.1
ENST00000378154.1
CASK

calcium/calmodulin-dependent serine protein kinase (MAGUK family)

chr17_-_40075219 1.168 ENST00000537919.1
ENST00000352035.2
ENST00000353196.1
ENST00000393896.2
ACLY



ATP citrate lyase



chr2_-_165477971 1.154 ENST00000446413.2
GRB14
growth factor receptor-bound protein 14
chr8_+_26240414 1.153 ENST00000380629.2
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr11_+_76494253 1.150 ENST00000333090.4
TSKU
tsukushi, small leucine rich proteoglycan
chr2_+_201171064 1.132 ENST00000451764.2
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr11_-_59436453 1.132 ENST00000300146.9
PATL1
protein associated with topoisomerase II homolog 1 (yeast)
chr1_-_19229248 1.130 ENST00000375341.3
ALDH4A1
aldehyde dehydrogenase 4 family, member A1
chr10_-_93392811 1.129 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr16_-_88851618 1.109 ENST00000301015.9
PIEZO1
piezo-type mechanosensitive ion channel component 1
chr22_-_30987837 1.107 ENST00000335214.6
PES1
pescadillo ribosomal biogenesis factor 1
chr18_-_46987000 1.106 ENST00000442713.2
ENST00000269445.6
DYM

dymeclin

chr12_+_57623477 1.095 ENST00000557487.1
ENST00000555634.1
ENST00000556689.1
SHMT2


serine hydroxymethyltransferase 2 (mitochondrial)


chr17_+_25621102 1.094 ENST00000581440.1
ENST00000262394.2
ENST00000583742.1
ENST00000579733.1
ENST00000583193.1
ENST00000581185.1
ENST00000427287.2
ENST00000348811.2
WSB1







WD repeat and SOCS box containing 1







chr16_-_4588822 1.079 ENST00000564828.1
CDIP1
cell death-inducing p53 target 1
chr17_-_8055747 1.077 ENST00000317276.4
ENST00000581703.1
PER1

period circadian clock 1

chr19_-_47354082 1.074 ENST00000593442.1
ENST00000263270.6
AP2S1

adaptor-related protein complex 2, sigma 1 subunit

chr3_+_47021168 1.061 ENST00000450053.3
ENST00000292309.5
ENST00000383740.2
NBEAL2


neurobeachin-like 2


chr17_+_64298944 1.059 ENST00000413366.3
PRKCA
protein kinase C, alpha
chr10_-_76995769 1.055 ENST00000372538.3
COMTD1
catechol-O-methyltransferase domain containing 1
chr1_+_40420802 1.049 ENST00000372811.5
ENST00000420632.2
ENST00000434861.1
ENST00000372809.5
MFSD2A



major facilitator superfamily domain containing 2A



chr18_-_33077868 1.042 ENST00000590757.1
ENST00000592173.1
ENST00000441607.2
ENST00000587450.1
ENST00000589258.1
INO80C



RP11-322E11.6
INO80 complex subunit C



Uncharacterized protein
chr19_-_47354023 1.040 ENST00000601649.1
ENST00000599990.1
ENST00000352203.4
AP2S1


adaptor-related protein complex 2, sigma 1 subunit


chr19_-_45657028 1.035 ENST00000429338.1
ENST00000589776.1
NKPD1

NTPase, KAP family P-loop domain containing 1

chr9_+_103235365 1.031 ENST00000374879.4
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr6_-_43484621 1.023 ENST00000506469.1
ENST00000503972.1
YIPF3

Yip1 domain family, member 3

chr1_-_205744574 1.020 ENST00000367139.3
ENST00000235932.4
ENST00000437324.2
ENST00000414729.1
RAB7L1



RAB7, member RAS oncogene family-like 1



chr22_-_30234218 1.012 ENST00000307790.3
ENST00000542393.1
ENST00000397771.2
ASCC2


activating signal cointegrator 1 complex subunit 2


chr11_+_844067 1.007 ENST00000397406.1
ENST00000409543.2
ENST00000525201.1
TSPAN4


tetraspanin 4


chr12_-_53242770 1.006 ENST00000304620.4
ENST00000547110.1
KRT78

keratin 78

chr6_+_7727030 0.999 ENST00000283147.6
BMP6
bone morphogenetic protein 6
chr19_-_39440495 0.985 ENST00000448145.2
ENST00000599996.1
SARS2
CTC-360G5.8
seryl-tRNA synthetase 2, mitochondrial
Serine--tRNA ligase, mitochondrial
chr1_-_205744205 0.983 ENST00000446390.2
RAB7L1
RAB7, member RAS oncogene family-like 1
chr1_+_214776516 0.965 ENST00000366955.3
CENPF
centromere protein F, 350/400kDa
chr19_-_47353547 0.962 ENST00000601498.1
AP2S1
adaptor-related protein complex 2, sigma 1 subunit
chr15_-_34659349 0.961 ENST00000314891.6
LPCAT4
lysophosphatidylcholine acyltransferase 4
chr2_+_201171372 0.958 ENST00000409140.3
SPATS2L
spermatogenesis associated, serine-rich 2-like
chr12_+_58013693 0.954 ENST00000320442.4
ENST00000379218.2
SLC26A10

solute carrier family 26, member 10

chrX_+_24483338 0.953 ENST00000379162.4
ENST00000441463.2
PDK3

pyruvate dehydrogenase kinase, isozyme 3

chr2_-_220118631 0.952 ENST00000248437.4
TUBA4A
tubulin, alpha 4a
chr18_-_13726510 0.948 ENST00000322247.3
ENST00000592976.1
ENST00000402563.1
ENST00000591269.1
FAM210A



family with sequence similarity 210, member A



chr9_+_103204553 0.945 ENST00000334943.6
ENST00000502978.1
TMEFF1
MSANTD3-TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
MSANTD3-TMEFF1 readthrough
chr19_+_1407517 0.935 ENST00000336761.6
ENST00000233078.4
DAZAP1

DAZ associated protein 1

chr15_-_71055769 0.934 ENST00000539319.1
UACA
uveal autoantigen with coiled-coil domains and ankyrin repeats
chr1_-_8939265 0.929 ENST00000489867.1
ENO1
enolase 1, (alpha)
chr1_+_230202936 0.927 ENST00000366672.4
GALNT2
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 2 (GalNAc-T2)
chr19_-_14628645 0.925 ENST00000598235.1
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr9_-_110251836 0.923 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr17_-_882966 0.921 ENST00000336868.3
NXN
nucleoredoxin
chr1_-_19229014 0.921 ENST00000538839.1
ENST00000290597.5
ALDH4A1

aldehyde dehydrogenase 4 family, member A1

chr1_-_159915386 0.919 ENST00000361509.3
ENST00000368094.1
IGSF9

immunoglobulin superfamily, member 9

chr6_-_43484718 0.914 ENST00000372422.2
YIPF3
Yip1 domain family, member 3
chr13_-_44361025 0.912 ENST00000261488.6
ENOX1
ecto-NOX disulfide-thiol exchanger 1
chr21_-_38639601 0.910 ENST00000539844.1
ENST00000476950.1
ENST00000399001.1
DSCR3


Down syndrome critical region gene 3


chr11_+_69455855 0.909 ENST00000227507.2
ENST00000536559.1
CCND1

cyclin D1

chr20_-_10654639 0.900 ENST00000254958.5
JAG1
jagged 1
chr1_-_111991908 0.896 ENST00000235090.5
WDR77
WD repeat domain 77
chr12_-_33049690 0.890 ENST00000070846.6
ENST00000340811.4
PKP2

plakophilin 2

chr13_+_52158610 0.887 ENST00000298125.5
WDFY2
WD repeat and FYVE domain containing 2
chr12_+_7023735 0.883 ENST00000538763.1
ENST00000544774.1
ENST00000545045.2
ENO2


enolase 2 (gamma, neuronal)


chr17_+_80416050 0.867 ENST00000579198.1
ENST00000390006.4
ENST00000580296.1
NARF


nuclear prelamin A recognition factor


chr2_+_201170770 0.866 ENST00000409988.3
ENST00000409385.1
SPATS2L

spermatogenesis associated, serine-rich 2-like

chr12_+_27677085 0.865 ENST00000545334.1
ENST00000540114.1
ENST00000537927.1
ENST00000318304.8
ENST00000535047.1
ENST00000542629.1
ENST00000228425.6
PPFIBP1






PTPRF interacting protein, binding protein 1 (liprin beta 1)






chr19_-_663277 0.855 ENST00000292363.5
RNF126
ring finger protein 126
chrX_+_23685563 0.853 ENST00000379341.4
PRDX4
peroxiredoxin 4
chr1_-_43833628 0.851 ENST00000413844.2
ENST00000372458.3
ELOVL1

ELOVL fatty acid elongase 1

chr12_-_53614155 0.847 ENST00000543726.1
RARG
retinoic acid receptor, gamma
chr20_+_32951041 0.846 ENST00000374864.4
ITCH
itchy E3 ubiquitin protein ligase
chr1_-_19578003 0.845 ENST00000375199.3
ENST00000375208.3
ENST00000356068.2
ENST00000477853.1
EMC1



ER membrane protein complex subunit 1



chr5_+_6633534 0.843 ENST00000537411.1
ENST00000538824.1
SRD5A1

steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)

chr4_+_177241094 0.840 ENST00000503362.1
SPCS3
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr12_-_53614043 0.839 ENST00000338561.5
RARG
retinoic acid receptor, gamma
chr17_-_33469299 0.833 ENST00000586869.1
ENST00000360831.5
ENST00000442241.4
NLE1


notchless homolog 1 (Drosophila)


chr17_-_73127353 0.833 ENST00000580423.1
ENST00000578337.1
ENST00000582160.1
NT5C


5', 3'-nucleotidase, cytosolic


chr5_-_172198190 0.826 ENST00000239223.3
DUSP1
dual specificity phosphatase 1
chr5_+_55033845 0.824 ENST00000353507.5
ENST00000514278.2
ENST00000505374.1
ENST00000506511.1
DDX4



DEAD (Asp-Glu-Ala-Asp) box polypeptide 4



chr16_-_4588469 0.821 ENST00000588381.1
ENST00000563332.2
CDIP1

cell death-inducing p53 target 1

chr20_+_17949724 0.820 ENST00000377704.4
MGME1
mitochondrial genome maintenance exonuclease 1
chr7_-_56119238 0.817 ENST00000275605.3
ENST00000395471.3
PSPH

phosphoserine phosphatase

chr12_+_7023491 0.815 ENST00000541477.1
ENST00000229277.1
ENO2

enolase 2 (gamma, neuronal)

chr3_-_185826855 0.806 ENST00000306376.5
ETV5
ets variant 5
chr9_+_2622085 0.799 ENST00000382099.2
VLDLR
very low density lipoprotein receptor
chr9_-_35732362 0.796 ENST00000314888.9
ENST00000540444.1
TLN1

talin 1

chr22_+_24236191 0.794 ENST00000215754.7
MIF
macrophage migration inhibitory factor (glycosylation-inhibiting factor)
chr3_+_10857885 0.793 ENST00000254488.2
ENST00000454147.1
SLC6A11

solute carrier family 6 (neurotransmitter transporter), member 11

chr5_+_9546306 0.785 ENST00000508179.1
SNHG18
small nucleolar RNA host gene 18 (non-protein coding)
chr3_-_57583185 0.785 ENST00000463880.1
ARF4
ADP-ribosylation factor 4
chr11_-_116968987 0.784 ENST00000434315.2
ENST00000292055.4
ENST00000375288.1
ENST00000542607.1
ENST00000445177.1
ENST00000375300.1
ENST00000446921.2
SIK3






SIK family kinase 3






chr22_-_30987849 0.781 ENST00000402284.3
ENST00000354694.7
PES1

pescadillo ribosomal biogenesis factor 1

chr11_+_18416103 0.778 ENST00000543445.1
ENST00000430553.2
ENST00000396222.2
ENST00000535451.1
LDHA



lactate dehydrogenase A



chr16_+_3070313 0.777 ENST00000326577.4
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr5_+_34656569 0.773 ENST00000428746.2
RAI14
retinoic acid induced 14
chr11_+_18416133 0.761 ENST00000227157.4
ENST00000478970.2
ENST00000495052.1
LDHA


lactate dehydrogenase A


chr15_+_62359175 0.759 ENST00000355522.5
C2CD4A
C2 calcium-dependent domain containing 4A
chr15_+_74908147 0.757 ENST00000568139.1
ENST00000563297.1
ENST00000568488.1
ENST00000352989.5
ENST00000348245.3
CLK3




CDC-like kinase 3




chr12_+_71833756 0.757 ENST00000536515.1
ENST00000540815.2
LGR5

leucine-rich repeat containing G protein-coupled receptor 5

chr14_+_65453432 0.755 ENST00000246166.2
FNTB
farnesyltransferase, CAAX box, beta
chr2_+_113403434 0.754 ENST00000272542.3
SLC20A1
solute carrier family 20 (phosphate transporter), member 1
chr19_+_10765003 0.750 ENST00000407004.3
ENST00000589998.1
ENST00000589600.1
ILF3


interleukin enhancer binding factor 3, 90kDa


chr8_-_30515693 0.745 ENST00000355904.4
GTF2E2
general transcription factor IIE, polypeptide 2, beta 34kDa
chr19_+_6739662 0.741 ENST00000313285.8
ENST00000313244.9
ENST00000596758.1
TRIP10


thyroid hormone receptor interactor 10


chrX_+_51075658 0.740 ENST00000356450.2
NUDT10
nudix (nucleoside diphosphate linked moiety X)-type motif 10
chr3_+_38206975 0.738 ENST00000446845.1
ENST00000311806.3
OXSR1

oxidative stress responsive 1

chr11_-_82444892 0.737 ENST00000329203.3
FAM181B
family with sequence similarity 181, member B
chr12_+_15475462 0.733 ENST00000543886.1
ENST00000348962.2
PTPRO

protein tyrosine phosphatase, receptor type, O

chr12_+_54674482 0.733 ENST00000547708.1
ENST00000340913.6
ENST00000551702.1
ENST00000330752.8
ENST00000547276.1
HNRNPA1




heterogeneous nuclear ribonucleoprotein A1




chr16_+_2867228 0.727 ENST00000005995.3
ENST00000574813.1
PRSS21

protease, serine, 21 (testisin)

chr9_+_79792410 0.725 ENST00000357409.5
VPS13A
vacuolar protein sorting 13 homolog A (S. cerevisiae)
chr5_+_34656331 0.725 ENST00000265109.3
RAI14
retinoic acid induced 14
chr20_+_17949684 0.719 ENST00000377709.1
MGME1
mitochondrial genome maintenance exonuclease 1
chr9_-_138591341 0.715 ENST00000298466.5
ENST00000425225.1
SOHLH1

spermatogenesis and oogenesis specific basic helix-loop-helix 1

chr5_+_6633456 0.708 ENST00000274192.5
SRD5A1
steroid-5-alpha-reductase, alpha polypeptide 1 (3-oxo-5 alpha-steroid delta 4-dehydrogenase alpha 1)
chr17_-_73127778 0.706 ENST00000578407.1
NT5C
5', 3'-nucleotidase, cytosolic
chr4_+_57301896 0.700 ENST00000514888.1
ENST00000264221.2
ENST00000505164.1
PAICS


phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.2 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
1.1 5.7 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
1.0 7.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
1.0 3.0 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.9 3.7 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.9 2.7 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.8 2.5 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.8 2.4 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.8 3.1 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.8 2.3 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.7 4.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.7 2.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.7 7.9 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.5 3.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.5 6.4 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.5 7.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.4 2.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.4 3.0 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795)
0.4 2.1 GO:0019470 4-hydroxyproline catabolic process(GO:0019470)
0.4 1.9 GO:0002159 desmosome assembly(GO:0002159)
0.4 2.3 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.4 1.5 GO:0032811 negative regulation of epinephrine secretion(GO:0032811) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.4 2.2 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.3 1.7 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.3 1.6 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.3 1.0 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.3 1.3 GO:0042360 vitamin E metabolic process(GO:0042360)
0.3 0.9 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.3 1.5 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.3 1.5 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.3 1.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.3 7.6 GO:0031639 plasminogen activation(GO:0031639)
0.3 1.3 GO:0048817 negative regulation of hair follicle maturation(GO:0048817)
0.3 1.3 GO:0060356 leucine import(GO:0060356)
0.3 0.8 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 0.7 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.2 0.7 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.2 0.7 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2 1.7 GO:2000323 negative regulation of glucocorticoid receptor signaling pathway(GO:2000323)
0.2 1.7 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.2 2.3 GO:0046940 nucleoside monophosphate phosphorylation(GO:0046940)
0.2 2.1 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.2 0.7 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.2 1.6 GO:0060992 response to fungicide(GO:0060992)
0.2 1.3 GO:1903977 positive regulation of glial cell migration(GO:1903977)
0.2 1.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.2 0.6 GO:0045658 regulation of eosinophil differentiation(GO:0045643) positive regulation of eosinophil differentiation(GO:0045645) regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 3.3 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.2 0.6 GO:0021718 superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.2 0.8 GO:0021592 fourth ventricle development(GO:0021592)
0.2 1.0 GO:0090031 positive regulation of steroid hormone biosynthetic process(GO:0090031)
0.2 0.8 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.2 2.1 GO:0007000 nucleolus organization(GO:0007000)
0.2 2.5 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 1.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.2 0.6 GO:0003358 noradrenergic neuron development(GO:0003358)
0.2 0.9 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) protein O-linked glycosylation via threonine(GO:0018243)
0.2 3.9 GO:0032802 low-density lipoprotein particle receptor catabolic process(GO:0032802)
0.2 2.2 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 2.0 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.2 0.7 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.2 0.8 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.2 0.3 GO:0072034 renal vesicle induction(GO:0072034)
0.2 0.3 GO:0035669 TRAM-dependent toll-like receptor signaling pathway(GO:0035668) TRAM-dependent toll-like receptor 4 signaling pathway(GO:0035669)
0.2 0.5 GO:0018194 N-terminal protein amino acid methylation(GO:0006480) N-terminal peptidyl-alanine methylation(GO:0018011) N-terminal peptidyl-alanine trimethylation(GO:0018012) N-terminal peptidyl-glycine methylation(GO:0018013) N-terminal peptidyl-proline dimethylation(GO:0018016) peptidyl-alanine modification(GO:0018194) N-terminal peptidyl-proline methylation(GO:0035568) N-terminal peptidyl-serine methylation(GO:0035570) N-terminal peptidyl-serine dimethylation(GO:0035572) N-terminal peptidyl-serine trimethylation(GO:0035573)
0.2 0.5 GO:0043686 co-translational protein modification(GO:0043686)
0.2 1.5 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.2 0.6 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.2 1.6 GO:0048702 embryonic neurocranium morphogenesis(GO:0048702)
0.2 1.5 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 0.9 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.4 GO:0070407 oxidation-dependent protein catabolic process(GO:0070407)
0.1 0.6 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 2.3 GO:0051639 actin filament network formation(GO:0051639)
0.1 2.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.4 GO:1990869 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.1 0.4 GO:0071335 submandibular salivary gland formation(GO:0060661) hair follicle cell proliferation(GO:0071335) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.1 1.4 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.6 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.1 1.1 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 0.4 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.1 0.4 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057)
0.1 2.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.1 0.8 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.4 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.8 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.1 0.6 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.4 GO:1990258 box C/D snoRNA 3'-end processing(GO:0000494) box C/D snoRNA metabolic process(GO:0033967) box C/D snoRNA processing(GO:0034963) histone glutamine methylation(GO:1990258)
0.1 0.9 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.8 GO:2000286 receptor internalization involved in canonical Wnt signaling pathway(GO:2000286)
0.1 0.6 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.5 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1 1.9 GO:0006089 lactate metabolic process(GO:0006089)
0.1 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 3.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 0.3 GO:0032679 TRAIL production(GO:0032639) regulation of TRAIL production(GO:0032679) positive regulation of TRAIL production(GO:0032759)
0.1 1.0 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.9 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1 0.6 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.5 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.4 GO:1900180 regulation of protein localization to nucleus(GO:1900180)
0.1 0.9 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 1.1 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.1 0.5 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.6 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 0.6 GO:0080009 mRNA methylation(GO:0080009)
0.1 0.9 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.1 0.3 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.6 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.1 0.4 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.4 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 2.2 GO:0009223 pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.1 1.0 GO:0006183 GTP biosynthetic process(GO:0006183)
0.1 0.4 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.7 GO:0060699 regulation of endoribonuclease activity(GO:0060699)
0.1 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 0.3 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 1.1 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 0.6 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.3 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.1 1.5 GO:0034656 nucleobase-containing small molecule catabolic process(GO:0034656)
0.1 0.2 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.1 1.0 GO:0019532 oxalate transport(GO:0019532)
0.1 0.4 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 1.3 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.9 GO:0015886 heme transport(GO:0015886)
0.1 0.4 GO:0015862 uridine transport(GO:0015862)
0.1 0.3 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.1 1.0 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.1 1.5 GO:0019511 peptidyl-proline hydroxylation(GO:0019511)
0.1 1.3 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.1 0.6 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.1 0.8 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.1 0.7 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.2 GO:0006500 N-terminal protein palmitoylation(GO:0006500)
0.1 1.1 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.1 0.9 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.1 0.3 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.3 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.1 0.6 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.1 0.1 GO:0046833 positive regulation of RNA export from nucleus(GO:0046833)
0.1 2.7 GO:0032456 endocytic recycling(GO:0032456)
0.1 0.6 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 1.1 GO:0097286 iron ion import(GO:0097286)
0.1 1.0 GO:0051382 kinetochore assembly(GO:0051382)
0.1 1.3 GO:0045056 transcytosis(GO:0045056)
0.1 0.5 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.1 0.5 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.3 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 2.9 GO:0006730 one-carbon metabolic process(GO:0006730)
0.1 0.5 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.8 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 1.7 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.1 0.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 5.3 GO:0009301 snRNA transcription(GO:0009301) snRNA transcription from RNA polymerase II promoter(GO:0042795)
0.1 0.4 GO:0036089 cleavage furrow formation(GO:0036089)
0.1 1.4 GO:0032288 myelin assembly(GO:0032288)
0.1 0.5 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.0 2.5 GO:0031076 embryonic camera-type eye development(GO:0031076)
0.0 1.0 GO:0006265 DNA topological change(GO:0006265)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.3 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:1905075 occluding junction disassembly(GO:1905071) regulation of occluding junction disassembly(GO:1905073) positive regulation of occluding junction disassembly(GO:1905075)
0.0 0.6 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.3 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.7 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 1.0 GO:0036148 phosphatidylglycerol acyl-chain remodeling(GO:0036148)
0.0 0.3 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.3 GO:0048619 embryonic hindgut morphogenesis(GO:0048619)
0.0 1.7 GO:0017145 stem cell division(GO:0017145)
0.0 1.3 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.4 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.4 GO:0019233 sensory perception of pain(GO:0019233)
0.0 0.5 GO:0042074 cell migration involved in gastrulation(GO:0042074)
0.0 3.1 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.6 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 1.3 GO:0006907 pinocytosis(GO:0006907)
0.0 0.1 GO:0032849 positive regulation of cellular pH reduction(GO:0032849)
0.0 0.8 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.0 0.4 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.6 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 1.2 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.2 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.2 GO:0051029 rRNA transport(GO:0051029)
0.0 0.5 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:1901165 negative regulation of MDA-5 signaling pathway(GO:0039534) positive regulation of trophoblast cell migration(GO:1901165)
0.0 1.2 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.9 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.8 GO:0006465 signal peptide processing(GO:0006465)
0.0 1.2 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627)
0.0 0.3 GO:0014877 response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 6.6 GO:0006338 chromatin remodeling(GO:0006338)
0.0 1.2 GO:0018146 keratan sulfate biosynthetic process(GO:0018146)
0.0 0.6 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.4 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)
0.0 0.1 GO:0000472 endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000472) rRNA 5'-end processing(GO:0000967) ncRNA 5'-end processing(GO:0034471)
0.0 2.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.7 GO:0034315 regulation of Arp2/3 complex-mediated actin nucleation(GO:0034315)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.1 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.0 1.8 GO:0005978 glycogen biosynthetic process(GO:0005978) glucan biosynthetic process(GO:0009250)
0.0 0.8 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.5 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.6 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 3.4 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.3 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.4 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
0.0 1.5 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.1 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.3 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:0043932 ossification involved in bone remodeling(GO:0043932)
0.0 1.2 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.8 GO:0009994 oocyte differentiation(GO:0009994)
0.0 1.2 GO:0032465 regulation of cytokinesis(GO:0032465)
0.0 0.4 GO:0002076 osteoblast development(GO:0002076)
0.0 0.1 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.3 GO:0048511 rhythmic process(GO:0048511)
0.0 0.4 GO:1900116 extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.0 0.2 GO:0006370 7-methylguanosine mRNA capping(GO:0006370)
0.0 0.3 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity(GO:0051091)
0.0 0.1 GO:0051182 coenzyme transport(GO:0051182)
0.0 0.4 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.5 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.2 GO:0030220 platelet formation(GO:0030220)
0.0 0.4 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.6 GO:0002042 cell migration involved in sprouting angiogenesis(GO:0002042)
0.0 0.8 GO:1901222 regulation of NIK/NF-kappaB signaling(GO:1901222)
0.0 0.5 GO:0007129 synapsis(GO:0007129)
0.0 0.2 GO:0018027 peptidyl-lysine dimethylation(GO:0018027)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.3 GO:0048477 oogenesis(GO:0048477)
0.0 0.5 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.5 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.0 1.1 GO:0006501 C-terminal protein lipidation(GO:0006501)
0.0 0.1 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.0 0.3 GO:0098781 ncRNA transcription(GO:0098781)
0.0 0.5 GO:0060338 regulation of type I interferon-mediated signaling pathway(GO:0060338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
1.1 3.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.6 3.1 GO:0070876 SOSS complex(GO:0070876)
0.5 3.3 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.4 3.3 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.3 1.7 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.3 2.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.3 4.7 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.3 0.8 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.3 1.9 GO:0070545 PeBoW complex(GO:0070545)
0.3 1.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.2 0.7 GO:0031045 dense core granule(GO:0031045)
0.2 7.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.2 6.9 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.2 0.8 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.2 0.8 GO:0097513 myosin II filament(GO:0097513)
0.2 1.6 GO:0070852 cell body fiber(GO:0070852)
0.2 0.6 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 2.8 GO:0005652 nuclear lamina(GO:0005652)
0.1 0.6 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.6 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 3.1 GO:0036020 endolysosome membrane(GO:0036020)
0.1 0.7 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.8 GO:0071547 piP-body(GO:0071547)
0.1 1.1 GO:0070552 BRISC complex(GO:0070552)
0.1 1.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 0.5 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.7 GO:0097452 GAIT complex(GO:0097452)
0.1 3.1 GO:0031528 microvillus membrane(GO:0031528)
0.1 0.3 GO:0005960 glycine cleavage complex(GO:0005960)
0.1 0.8 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 0.5 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 5.9 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.3 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 1.0 GO:0031298 replication fork protection complex(GO:0031298)
0.1 2.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 1.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 1.0 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 2.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.1 0.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 0.4 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 1.9 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.6 GO:0036449 microtubule minus-end(GO:0036449)
0.1 0.4 GO:0001652 granular component(GO:0001652)
0.1 0.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.7 GO:0032039 integrator complex(GO:0032039)
0.1 0.9 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.5 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.7 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 2.3 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.4 GO:0000322 storage vacuole(GO:0000322)
0.0 0.6 GO:0072546 ER membrane protein complex(GO:0072546)
0.0 0.3 GO:0031415 NatA complex(GO:0031415)
0.0 4.8 GO:0035578 azurophil granule lumen(GO:0035578)
0.0 0.4 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 1.9 GO:0002102 podosome(GO:0002102)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.7 GO:0001891 phagocytic cup(GO:0001891)
0.0 2.9 GO:0005811 lipid particle(GO:0005811)
0.0 1.4 GO:0043034 costamere(GO:0043034)
0.0 2.2 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 1.3 GO:0031941 filamentous actin(GO:0031941)
0.0 1.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.7 GO:0005922 connexon complex(GO:0005922)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.3 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 3.2 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 1.4 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.8 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0000333 telomerase catalytic core complex(GO:0000333)
0.0 0.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 2.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 2.0 GO:0030175 filopodium(GO:0030175)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 3.5 GO:0001726 ruffle(GO:0001726)
0.0 0.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.1 GO:0045177 apical part of cell(GO:0045177)
0.0 5.3 GO:0005938 cell cortex(GO:0005938)
0.0 1.4 GO:0043195 terminal bouton(GO:0043195)
0.0 1.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.1 GO:0101003 ficolin-1-rich granule membrane(GO:0101003)
0.0 0.0 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.7 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.2 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.0 GO:0045095 keratin filament(GO:0045095)
0.0 1.4 GO:0030426 growth cone(GO:0030426)
0.0 2.5 GO:0005819 spindle(GO:0005819)
0.0 0.3 GO:0010369 chromocenter(GO:0010369)
0.0 0.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.0 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 3.7 GO:0045121 membrane raft(GO:0045121)
0.0 1.8 GO:0030666 endocytic vesicle membrane(GO:0030666)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 8.2 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
2.0 6.0 GO:0004618 phosphoglycerate kinase activity(GO:0004618)
1.8 7.3 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
1.0 4.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
1.0 3.0 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.8 3.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.7 0.7 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.6 1.9 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.6 3.2 GO:0004924 oncostatin-M receptor activity(GO:0004924)
0.5 1.5 GO:0004938 alpha2-adrenergic receptor activity(GO:0004938)
0.5 3.3 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.4 2.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.4 6.5 GO:0008179 adenylate cyclase binding(GO:0008179)
0.4 1.9 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.4 2.2 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.4 1.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.4 1.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.4 1.1 GO:0035403 histone kinase activity (H3-T6 specific)(GO:0035403)
0.3 3.0 GO:0043426 MRF binding(GO:0043426)
0.3 1.0 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.3 1.0 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.3 1.0 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.3 1.2 GO:0004461 lactose synthase activity(GO:0004461)
0.3 2.4 GO:0016842 amidine-lyase activity(GO:0016842)
0.3 1.2 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.3 3.0 GO:0004075 biotin carboxylase activity(GO:0004075)
0.3 0.9 GO:0015439 heme-transporting ATPase activity(GO:0015439)
0.3 1.1 GO:0034046 poly(G) binding(GO:0034046)
0.3 2.0 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 0.8 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.3 6.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.3 1.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.2 1.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 4.9 GO:0035613 RNA stem-loop binding(GO:0035613)
0.2 2.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.2 1.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.2 0.6 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.2 0.6 GO:0038131 neuregulin receptor activity(GO:0038131)
0.2 1.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 2.1 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.2 0.8 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.2 0.8 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.2 0.9 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.2 0.7 GO:0043891 glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity(GO:0004365) glyceraldehyde-3-phosphate dehydrogenase (NAD(P)+) (phosphorylating) activity(GO:0043891)
0.2 1.4 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.2 0.7 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.2 0.5 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 0.5 GO:0071885 N-terminal protein N-methyltransferase activity(GO:0071885)
0.2 0.5 GO:0015235 cobalamin transporter activity(GO:0015235)
0.2 2.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.2 1.1 GO:0008732 glycine hydroxymethyltransferase activity(GO:0004372) threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2 1.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.4 GO:0070361 mitochondrial light strand promoter anti-sense binding(GO:0070361) mitochondrial heavy strand promoter anti-sense binding(GO:0070362) mitochondrial heavy strand promoter sense binding(GO:0070364)
0.1 0.7 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.8 GO:0051022 GDP-dissociation inhibitor binding(GO:0051021) Rho GDP-dissociation inhibitor binding(GO:0051022)
0.1 0.8 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.1 3.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.1 0.8 GO:0004167 dopachrome isomerase activity(GO:0004167)
0.1 0.8 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 2.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.1 1.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 1.0 GO:0070840 dynein complex binding(GO:0070840)
0.1 0.4 GO:1990259 protein-glutamine N-methyltransferase activity(GO:0036009) histone-glutamine methyltransferase activity(GO:1990259)
0.1 1.0 GO:1901612 cardiolipin binding(GO:1901612)
0.1 1.0 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.4 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 1.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 0.9 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.1 0.6 GO:0009378 four-way junction helicase activity(GO:0009378)
0.1 0.6 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.6 GO:0008296 3'-5'-exodeoxyribonuclease activity(GO:0008296)
0.1 0.9 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.3 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 1.8 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 1.8 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.4 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.1 2.1 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.1 2.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 2.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.3 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 1.0 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 1.3 GO:0005432 calcium:sodium antiporter activity(GO:0005432)
0.1 1.3 GO:0034452 dynactin binding(GO:0034452)
0.1 1.1 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.9 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.7 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.5 GO:0015295 solute:proton symporter activity(GO:0015295)
0.1 0.2 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 1.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 1.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.1 0.3 GO:0004047 aminomethyltransferase activity(GO:0004047)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 2.7 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.6 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.6 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.1 0.3 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.1 2.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.0 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 5.3 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.1 0.6 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.2 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 1.5 GO:0005521 lamin binding(GO:0005521)
0.1 0.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.4 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.1 0.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 2.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 1.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.7 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0030984 kininogen binding(GO:0030984)
0.0 1.3 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.8 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.1 GO:0031893 vasopressin receptor binding(GO:0031893)
0.0 2.3 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.6 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 1.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 1.2 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.9 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 0.6 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.5 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0000217 DNA secondary structure binding(GO:0000217)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.7 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.4 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.5 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 1.1 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.9 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 2.9 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 1.5 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.1 GO:0019888 protein phosphatase regulator activity(GO:0019888)
0.0 0.5 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.6 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.5 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.6 GO:0043236 laminin binding(GO:0043236)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.3 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.0 0.3 GO:0000339 RNA cap binding(GO:0000339)
0.0 4.4 GO:0015631 tubulin binding(GO:0015631)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 4.8 GO:0045296 cadherin binding(GO:0045296)
0.0 1.0 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.1 GO:0051539 iron-sulfur cluster binding(GO:0051536) 4 iron, 4 sulfur cluster binding(GO:0051539) metal cluster binding(GO:0051540)
0.0 0.6 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 1.7 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0048027 mRNA 5'-UTR binding(GO:0048027)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 7.3 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.2 5.5 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.1 18.1 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.1 3.6 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.1 4.6 PID_PLK1_PATHWAY PLK1 signaling events
0.1 1.3 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.1 1.8 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.1 1.4 SA_PTEN_PATHWAY PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate.
0.0 0.9 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.5 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.9 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 2.6 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.9 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport
0.0 2.7 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 2.4 PID_P53_REGULATION_PATHWAY p53 pathway
0.0 1.4 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.9 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.5 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.9 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 1.5 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 1.7 PID_IL4_2PATHWAY IL4-mediated signaling events
0.0 0.8 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.7 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 2.0 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.5 ST_PHOSPHOINOSITIDE_3_KINASE_PATHWAY PI3K Pathway
0.0 1.2 PID_INSULIN_PATHWAY Insulin Pathway
0.0 1.7 PID_ILK_PATHWAY Integrin-linked kinase signaling
0.0 0.8 PID_RHOA_PATHWAY RhoA signaling pathway
0.0 2.1 PID_HDAC_CLASSI_PATHWAY Signaling events mediated by HDAC Class I
0.0 0.3 PID_FOXO_PATHWAY FoxO family signaling
0.0 0.8 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.2 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.6 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.3 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.7 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 16.0 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.3 6.4 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.2 4.5 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 11.7 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.2 1.7 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.2 2.8 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.2 0.5 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.1 6.6 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.1 2.1 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 0.3 REACTOME_NEP_NS2_INTERACTS_WITH_THE_CELLULAR_EXPORT_MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.1 2.5 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 1.5 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 2.9 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 0.4 REACTOME_SCF_BETA_TRCP_MEDIATED_DEGRADATION_OF_EMI1 Genes involved in SCF-beta-TrCP mediated degradation of Emi1
0.1 3.4 REACTOME_INHIBITION_OF_THE_PROTEOLYTIC_ACTIVITY_OF_APC_C_REQUIRED_FOR_THE_ONSET_OF_ANAPHASE_BY_MITOTIC_SPINDLE_CHECKPOINT_COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
0.1 1.1 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 4.8 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.1 1.2 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.8 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.6 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 2.3 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 3.1 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.1 0.8 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 1.1 REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.1 1.0 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.1 1.3 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.2 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.1 1.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.7 REACTOME_GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.8 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.6 REACTOME_REMOVAL_OF_THE_FLAP_INTERMEDIATE_FROM_THE_C_STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.4 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.3 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 2.4 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.6 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 2.9 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 1.3 REACTOME_BASIGIN_INTERACTIONS Genes involved in Basigin interactions
0.0 1.4 REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 2.6 REACTOME_METABOLISM_OF_NON_CODING_RNA Genes involved in Metabolism of non-coding RNA
0.0 1.0 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.4 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.7 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.8 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.5 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 1.1 REACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 2.0 REACTOME_PLATELET_AGGREGATION_PLUG_FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.3 REACTOME_IKK_COMPLEX_RECRUITMENT_MEDIATED_BY_RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.7 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME_INFLUENZA_VIRAL_RNA_TRANSCRIPTION_AND_REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.0 4.1 REACTOME_SRP_DEPENDENT_COTRANSLATIONAL_PROTEIN_TARGETING_TO_MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.7 REACTOME_HOST_INTERACTIONS_OF_HIV_FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.4 REACTOME_DESTABILIZATION_OF_MRNA_BY_BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.5 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME_FORMATION_OF_THE_TERNARY_COMPLEX_AND_SUBSEQUENTLY_THE_43S_COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME_3_UTR_MEDIATED_TRANSLATIONAL_REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.6 REACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 1.3 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Late Phase of HIV Life Cycle
0.0 0.9 REACTOME_O_LINKED_GLYCOSYLATION_OF_MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.2 REACTOME_COPI_MEDIATED_TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.1 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.9 REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 2.9 REACTOME_METABOLISM_OF_AMINO_ACIDS_AND_DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.1 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway