Motif ID: CBFB
Z-value: 0.383
Transcription factors associated with CBFB:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
CBFB | ENSG00000067955.9 | CBFB |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
CBFB | hg19_v2_chr16_+_67062996_67063019 | 0.37 | 7.6e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.0 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
0.1 | 0.9 | GO:2001268 | negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268) |
0.1 | 0.5 | GO:0060480 | lung goblet cell differentiation(GO:0060480) |
0.1 | 0.5 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
0.1 | 0.4 | GO:0018879 | biphenyl metabolic process(GO:0018879) |
0.0 | 0.3 | GO:0050859 | negative regulation of B cell receptor signaling pathway(GO:0050859) |
0.0 | 0.1 | GO:1902162 | mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164) |
0.0 | 0.1 | GO:0045918 | negative regulation of cytolysis(GO:0045918) |
0.0 | 0.1 | GO:0003366 | cell-matrix adhesion involved in ameboidal cell migration(GO:0003366) |
0.0 | 0.2 | GO:0051388 | positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) |
0.0 | 0.1 | GO:0050955 | thermoception(GO:0050955) |
0.0 | 0.2 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
0.0 | 0.1 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
0.0 | 0.1 | GO:0070560 | protein secretion by platelet(GO:0070560) |
0.0 | 0.5 | GO:0006607 | NLS-bearing protein import into nucleus(GO:0006607) |
0.0 | 0.8 | GO:1904893 | negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.1 | GO:0030934 | anchoring collagen complex(GO:0030934) |
0.0 | 0.1 | GO:0034669 | integrin alpha4-beta7 complex(GO:0034669) |
0.0 | 0.1 | GO:0036449 | microtubule minus-end(GO:0036449) |
0.0 | 0.9 | GO:1904724 | tertiary granule lumen(GO:1904724) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.0 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.0 | 0.5 | GO:0015643 | toxic substance binding(GO:0015643) |
0.0 | 0.1 | GO:0036361 | racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661) |
0.0 | 0.1 | GO:0030020 | extracellular matrix structural constituent conferring tensile strength(GO:0030020) |
0.0 | 0.5 | GO:0000175 | 3'-5'-exoribonuclease activity(GO:0000175) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.9 | PID_AVB3_OPN_PATHWAY | Osteopontin-mediated events |
0.0 | 0.8 | NABA_PROTEOGLYCANS | Genes encoding proteoglycans |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.9 | REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX | Genes involved in Degradation of the extracellular matrix |
0.0 | 0.5 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |