Motif ID: CPEB1

Z-value: 0.790


Transcription factors associated with CPEB1:

Gene SymbolEntrez IDGene Name
CPEB1 ENSG00000214575.5 CPEB1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
CPEB1hg19_v2_chr15_-_83240507_83240539-0.145.2e-01Click!


Activity profile for motif CPEB1.

activity profile for motif CPEB1


Sorted Z-values histogram for motif CPEB1

Sorted Z-values for motif CPEB1



Network of associatons between targets according to the STRING database.



First level regulatory network of CPEB1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_4385230 1.504 ENST00000536537.1
CCND2
cyclin D2
chr13_-_20805109 1.012 ENST00000241124.6
GJB6
gap junction protein, beta 6, 30kDa
chr2_-_190044480 1.011 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr12_-_91539918 1.004 ENST00000548218.1
DCN
decorin
chr16_-_56459354 0.973 ENST00000290649.5
AMFR
autocrine motility factor receptor, E3 ubiquitin protein ligase
chr20_-_10654639 0.938 ENST00000254958.5
JAG1
jagged 1
chr6_+_12290586 0.893 ENST00000379375.5
EDN1
endothelin 1
chr2_+_114256661 0.868 ENST00000306507.5
FOXD4L1
forkhead box D4-like 1
chr6_+_15401075 0.841 ENST00000541660.1
JARID2
jumonji, AT rich interactive domain 2
chr9_+_105757590 0.806 ENST00000374798.3
ENST00000487798.1
CYLC2

cylicin, basic protein of sperm head cytoskeleton 2

chr18_-_31802056 0.752 ENST00000538587.1
NOL4
nucleolar protein 4
chrX_-_107682702 0.743 ENST00000372216.4
COL4A6
collagen, type IV, alpha 6
chr12_-_52845910 0.731 ENST00000252252.3
KRT6B
keratin 6B
chr4_-_47983519 0.710 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1


cyclic nucleotide gated channel alpha 1


chr14_+_79745746 0.704 ENST00000281127.7
NRXN3
neurexin 3
chr14_-_75079026 0.668 ENST00000261978.4
LTBP2
latent transforming growth factor beta binding protein 2
chr18_-_31628558 0.639 ENST00000535384.1
NOL4
nucleolar protein 4
chr18_+_34124507 0.629 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr1_+_84630053 0.625 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr10_-_105845674 0.614 ENST00000353479.5
ENST00000369733.3
COL17A1

collagen, type XVII, alpha 1

chr4_-_74864386 0.607 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr17_-_76220740 0.596 ENST00000600484.1
AC087645.1
Uncharacterized protein
chr8_-_57026541 0.594 ENST00000311923.1
MOS
v-mos Moloney murine sarcoma viral oncogene homolog
chr14_+_75746340 0.593 ENST00000555686.1
ENST00000555672.1
FOS

FBJ murine osteosarcoma viral oncogene homolog

chr1_+_84630645 0.589 ENST00000394839.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr20_+_58251716 0.585 ENST00000355648.4
PHACTR3
phosphatase and actin regulator 3
chr6_-_27114577 0.584 ENST00000356950.1
ENST00000396891.4
HIST1H2BK

histone cluster 1, H2bk

chr12_-_91572278 0.584 ENST00000425043.1
ENST00000420120.2
ENST00000441303.2
ENST00000456569.2
DCN



decorin



chr17_-_39553844 0.580 ENST00000251645.2
KRT31
keratin 31
chr15_+_45406519 0.573 ENST00000323030.5
DUOXA2
dual oxidase maturation factor 2
chr18_+_29027696 0.564 ENST00000257189.4
DSG3
desmoglein 3
chr2_-_2334888 0.563 ENST00000428368.2
ENST00000399161.2
MYT1L

myelin transcription factor 1-like

chr20_+_58179582 0.562 ENST00000371015.1
ENST00000395639.4
PHACTR3

phosphatase and actin regulator 3

chr1_-_156675535 0.558 ENST00000368221.1
CRABP2
cellular retinoic acid binding protein 2
chr9_+_70917276 0.538 ENST00000342833.2
FOXD4L3
forkhead box D4-like 3
chr4_-_116034979 0.534 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr20_-_46415341 0.533 ENST00000484875.1
ENST00000361612.4
SULF2

sulfatase 2

chr8_+_85095769 0.530 ENST00000518566.1
RALYL
RALY RNA binding protein-like
chr14_-_57277163 0.530 ENST00000555006.1
OTX2
orthodenticle homeobox 2
chr13_-_103719196 0.526 ENST00000245312.3
SLC10A2
solute carrier family 10 (sodium/bile acid cotransporter), member 2
chr12_-_52715179 0.525 ENST00000293670.3
KRT83
keratin 83
chr8_+_85095497 0.520 ENST00000522455.1
ENST00000521695.1
RALYL

RALY RNA binding protein-like

chr2_+_210444748 0.515 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr20_-_46415297 0.502 ENST00000467815.1
ENST00000359930.4
SULF2

sulfatase 2

chr8_+_77593448 0.502 ENST00000521891.2
ZFHX4
zinc finger homeobox 4
chr12_-_96184533 0.498 ENST00000343702.4
ENST00000344911.4
NTN4

netrin 4

chr11_+_35160709 0.495 ENST00000415148.2
ENST00000433354.2
ENST00000449691.2
ENST00000437706.2
ENST00000360158.4
ENST00000428726.2
ENST00000526669.2
ENST00000433892.2
ENST00000278386.6
ENST00000434472.2
ENST00000352818.4
ENST00000442151.2
CD44











CD44 molecule (Indian blood group)











chr3_+_99357319 0.494 ENST00000452013.1
ENST00000261037.3
ENST00000273342.4
COL8A1


collagen, type VIII, alpha 1


chr4_-_111119804 0.489 ENST00000394607.3
ENST00000302274.3
ELOVL6

ELOVL fatty acid elongase 6

chr3_+_101546827 0.485 ENST00000461724.1
ENST00000483180.1
ENST00000394054.2
NFKBIZ


nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta


chr12_-_81763184 0.478 ENST00000548670.1
ENST00000541570.2
ENST00000553058.1
PPFIA2


protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2


chr12_-_123201337 0.477 ENST00000528880.2
HCAR3
hydroxycarboxylic acid receptor 3
chr15_-_56209306 0.474 ENST00000506154.1
ENST00000338963.2
ENST00000508342.1
NEDD4


neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase


chr14_+_79745682 0.473 ENST00000557594.1
NRXN3
neurexin 3
chr12_-_122240792 0.468 ENST00000541657.1
ENST00000545885.1
ENST00000542933.1
ENST00000428029.2
ENST00000541694.1
ENST00000536662.1
ENST00000535643.1
RHOF
AC084018.1





ras homolog family member F (in filopodia)
AC084018.1





chr1_-_156675368 0.459 ENST00000368222.3
CRABP2
cellular retinoic acid binding protein 2
chrX_+_135278908 0.457 ENST00000539015.1
ENST00000370683.1
FHL1

four and a half LIM domains 1

chr18_-_31802282 0.453 ENST00000535475.1
NOL4
nucleolar protein 4
chr19_+_35634146 0.445 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD7


FXYD domain containing ion transport regulator 7


chr7_-_27205136 0.445 ENST00000396345.1
ENST00000343483.6
HOXA9

homeobox A9

chr6_+_15246501 0.443 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr17_-_76921459 0.442 ENST00000262768.7
TIMP2
TIMP metallopeptidase inhibitor 2
chr11_-_102826434 0.439 ENST00000340273.4
ENST00000260302.3
MMP13

matrix metallopeptidase 13 (collagenase 3)

chr12_-_81763127 0.432 ENST00000541017.1
PPFIA2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr11_-_102651343 0.431 ENST00000279441.4
ENST00000539681.1
MMP10

matrix metallopeptidase 10 (stromelysin 2)

chr9_-_118417 0.430 ENST00000382500.2
FOXD4
forkhead box D4
chr7_+_129984630 0.425 ENST00000355388.3
ENST00000497503.1
ENST00000463587.1
ENST00000461828.1
ENST00000494311.1
ENST00000466363.2
ENST00000485477.1
ENST00000431780.2
ENST00000474905.1
CPA5








carboxypeptidase A5








chr3_-_108248169 0.417 ENST00000273353.3
MYH15
myosin, heavy chain 15
chr7_-_20826504 0.413 ENST00000418710.2
ENST00000361443.4
SP8

Sp8 transcription factor

chr8_-_143999259 0.404 ENST00000323110.2
CYP11B2
cytochrome P450, family 11, subfamily B, polypeptide 2
chr4_-_52883786 0.401 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr8_+_77593474 0.401 ENST00000455469.2
ENST00000050961.6
ZFHX4

zinc finger homeobox 4

chrX_+_135279179 0.401 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr3_-_54962100 0.397 ENST00000273286.5
LRTM1
leucine-rich repeats and transmembrane domains 1
chr2_+_105050794 0.392 ENST00000429464.1
ENST00000414442.1
ENST00000447380.1
AC013402.2


long intergenic non-protein coding RNA 1102


chr10_+_102106829 0.391 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr12_-_92536433 0.387 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79


chromosome 12 open reading frame 79


chr9_+_42717234 0.387 ENST00000377590.1
FOXD4L2
forkhead box D4-like 2
chr9_+_116263778 0.387 ENST00000394646.3
RGS3
regulator of G-protein signaling 3
chr14_+_22309368 0.386 ENST00000390433.1
TRAV12-1
T cell receptor alpha variable 12-1
chr17_-_15244894 0.379 ENST00000338696.2
ENST00000543896.1
ENST00000539245.1
ENST00000539316.1
ENST00000395930.1
TEKT3




tektin 3




chr18_-_35145728 0.377 ENST00000361795.5
ENST00000603232.1
CELF4

CUGBP, Elav-like family member 4

chr6_+_31683117 0.375 ENST00000375825.3
ENST00000375824.1
LY6G6D

lymphocyte antigen 6 complex, locus G6D

chr20_+_16729003 0.367 ENST00000246081.2
OTOR
otoraplin
chr1_+_26485511 0.361 ENST00000374268.3
FAM110D
family with sequence similarity 110, member D
chr9_-_21995249 0.357 ENST00000494262.1
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr9_+_116263639 0.356 ENST00000343817.5
RGS3
regulator of G-protein signaling 3
chr12_-_52967600 0.355 ENST00000549343.1
ENST00000305620.2
KRT74

keratin 74

chr4_-_74904398 0.355 ENST00000296026.4
CXCL3
chemokine (C-X-C motif) ligand 3
chr5_-_147162263 0.349 ENST00000333010.6
ENST00000265272.5
JAKMIP2

janus kinase and microtubule interacting protein 2

chr1_+_209848749 0.345 ENST00000367029.4
G0S2
G0/G1switch 2
chr12_-_52779433 0.343 ENST00000257951.3
KRT84
keratin 84
chr4_-_65275162 0.342 ENST00000381210.3
ENST00000507440.1
TECRL

trans-2,3-enoyl-CoA reductase-like

chr1_+_116654376 0.341 ENST00000369500.3
MAB21L3
mab-21-like 3 (C. elegans)
chrX_+_117957741 0.340 ENST00000310164.2
ZCCHC12
zinc finger, CCHC domain containing 12
chr2_-_85645545 0.340 ENST00000409275.1
CAPG
capping protein (actin filament), gelsolin-like
chr16_+_11439286 0.337 ENST00000312499.5
ENST00000576027.1
RMI2

RecQ mediated genome instability 2

chr9_+_5450503 0.331 ENST00000381573.4
ENST00000381577.3
CD274

CD274 molecule

chrX_+_100805496 0.330 ENST00000372829.3
ARMCX1
armadillo repeat containing, X-linked 1
chr18_+_22040620 0.330 ENST00000426880.2
HRH4
histamine receptor H4
chr17_-_36358166 0.329 ENST00000537432.1
TBC1D3
TBC1 domain family, member 3
chr11_+_69924397 0.323 ENST00000355303.5
ANO1
anoctamin 1, calcium activated chloride channel
chr8_+_70378852 0.321 ENST00000525061.1
ENST00000458141.2
ENST00000260128.4
SULF1


sulfatase 1


chr1_+_214161854 0.318 ENST00000435016.1
PROX1
prospero homeobox 1
chr1_+_221051699 0.311 ENST00000366903.6
HLX
H2.0-like homeobox
chr4_-_41750922 0.311 ENST00000226382.2
PHOX2B
paired-like homeobox 2b
chr5_-_27038683 0.311 ENST00000511822.1
ENST00000231021.4
CDH9

cadherin 9, type 2 (T1-cadherin)

chr5_-_141704566 0.310 ENST00000344120.4
ENST00000434127.2
SPRY4

sprouty homolog 4 (Drosophila)

chr8_-_93029865 0.309 ENST00000422361.2
RUNX1T1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_80531399 0.309 ENST00000409148.1
ENST00000415098.1
ENST00000452811.1
LRRTM1


leucine rich repeat transmembrane neuronal 1


chr9_-_21995300 0.308 ENST00000498628.2
CDKN2A
cyclin-dependent kinase inhibitor 2A
chr11_+_69924639 0.305 ENST00000538023.1
ENST00000398543.2
ANO1

anoctamin 1, calcium activated chloride channel

chr6_+_41604747 0.302 ENST00000419164.1
ENST00000373051.2
MDFI

MyoD family inhibitor

chr11_-_102714534 0.301 ENST00000299855.5
MMP3
matrix metallopeptidase 3 (stromelysin 1, progelatinase)
chr1_+_107683644 0.296 ENST00000370067.1
NTNG1
netrin G1
chr17_+_7211656 0.294 ENST00000416016.2
EIF5A
eukaryotic translation initiation factor 5A
chr20_+_42574317 0.294 ENST00000358131.5
TOX2
TOX high mobility group box family member 2
chr17_-_38911580 0.292 ENST00000312150.4
KRT25
keratin 25
chr2_-_30144432 0.291 ENST00000389048.3
ALK
anaplastic lymphoma receptor tyrosine kinase
chr1_-_167059830 0.291 ENST00000367868.3
GPA33
glycoprotein A33 (transmembrane)
chr2_+_169757750 0.290 ENST00000375363.3
ENST00000429379.2
ENST00000421979.1
G6PC2


glucose-6-phosphatase, catalytic, 2


chr3_-_196911002 0.289 ENST00000452595.1
DLG1
discs, large homolog 1 (Drosophila)
chr17_-_38938786 0.286 ENST00000301656.3
KRT27
keratin 27
chr11_-_57089671 0.284 ENST00000532437.1
TNKS1BP1
tankyrase 1 binding protein 1, 182kDa
chr3_+_57882024 0.279 ENST00000494088.1
SLMAP
sarcolemma associated protein
chr12_+_41221794 0.278 ENST00000547849.1
CNTN1
contactin 1
chr19_-_58485895 0.277 ENST00000314391.3
C19orf18
chromosome 19 open reading frame 18
chr6_+_134758827 0.277 ENST00000431422.1
LINC01010
long intergenic non-protein coding RNA 1010
chr17_-_39580775 0.274 ENST00000225550.3
KRT37
keratin 37
chr3_-_141747439 0.274 ENST00000467667.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr17_-_39637392 0.274 ENST00000246639.2
ENST00000393989.1
KRT35

keratin 35

chr4_-_102267953 0.273 ENST00000523694.2
ENST00000507176.1
PPP3CA

protein phosphatase 3, catalytic subunit, alpha isozyme

chr1_+_23037323 0.272 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPHB2



EPH receptor B2



chr1_-_11907829 0.268 ENST00000376480.3
NPPA
natriuretic peptide A
chr14_-_57277178 0.268 ENST00000339475.5
ENST00000554559.1
ENST00000555804.1
OTX2


orthodenticle homeobox 2


chr2_+_173292390 0.265 ENST00000442250.1
ENST00000458358.1
ENST00000409080.1
ITGA6


integrin, alpha 6


chr11_-_11374904 0.265 ENST00000528848.2
CSNK2A3
casein kinase 2, alpha 3 polypeptide
chr8_+_104831472 0.264 ENST00000262231.10
ENST00000507740.1
RIMS2

regulating synaptic membrane exocytosis 2

chr17_-_78450398 0.262 ENST00000306773.4
NPTX1
neuronal pentraxin I
chr7_+_26591441 0.261 ENST00000420912.1
ENST00000457000.1
ENST00000430426.1
AC004947.2


AC004947.2


chr7_-_81399411 0.260 ENST00000423064.2
HGF
hepatocyte growth factor (hepapoietin A; scatter factor)
chr4_-_76957214 0.259 ENST00000306621.3
CXCL11
chemokine (C-X-C motif) ligand 11
chr8_-_7681411 0.254 ENST00000334773.6
DEFB105A
defensin, beta 105A
chr17_-_39197699 0.254 ENST00000306271.4
KRTAP1-1
keratin associated protein 1-1
chr8_+_7345191 0.252 ENST00000335510.6
DEFB105B
defensin, beta 105B
chr6_-_130543958 0.252 ENST00000437477.2
ENST00000439090.2
SAMD3

sterile alpha motif domain containing 3

chr1_+_107683436 0.252 ENST00000370068.1
NTNG1
netrin G1
chr12_+_130646999 0.251 ENST00000539839.1
ENST00000229030.4
FZD10

frizzled family receptor 10

chr8_+_104892639 0.250 ENST00000436393.2
RIMS2
regulating synaptic membrane exocytosis 2
chr9_-_37034028 0.246 ENST00000520281.1
ENST00000446742.1
ENST00000522003.1
ENST00000523145.1
ENST00000414447.1
ENST00000377847.2
ENST00000377853.2
ENST00000377852.2
ENST00000523241.1
ENST00000520154.1
ENST00000358127.4
PAX5










paired box 5










chr3_-_196910721 0.245 ENST00000443183.1
DLG1
discs, large homolog 1 (Drosophila)
chr1_-_200379129 0.245 ENST00000367353.1
ZNF281
zinc finger protein 281
chr10_-_104262460 0.245 ENST00000446605.2
ENST00000369905.4
ENST00000545684.1
ACTR1A


ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)


chrX_+_144908928 0.244 ENST00000408967.2
TMEM257
transmembrane protein 257
chr5_+_140071178 0.244 ENST00000508522.1
ENST00000448069.2
HARS2

histidyl-tRNA synthetase 2, mitochondrial

chr3_-_99595037 0.243 ENST00000383694.2
FILIP1L
filamin A interacting protein 1-like
chr2_-_228244013 0.241 ENST00000304568.3
TM4SF20
transmembrane 4 L six family member 20
chr5_-_76935513 0.240 ENST00000306422.3
OTP
orthopedia homeobox
chr14_+_103058948 0.238 ENST00000262241.6
RCOR1
REST corepressor 1
chr15_-_55562479 0.237 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr1_-_32110467 0.236 ENST00000440872.2
ENST00000373703.4
PEF1

penta-EF-hand domain containing 1

chr2_+_173292280 0.236 ENST00000264107.7
ITGA6
integrin, alpha 6
chr1_-_152552980 0.234 ENST00000368787.3
LCE3D
late cornified envelope 3D
chr18_+_29769978 0.233 ENST00000269202.6
ENST00000581447.1
MEP1B

meprin A, beta

chr2_+_207308220 0.233 ENST00000264377.3
ADAM23
ADAM metallopeptidase domain 23
chr13_-_67802549 0.231 ENST00000328454.5
ENST00000377865.2
PCDH9

protocadherin 9

chr17_-_39471947 0.229 ENST00000334202.3
KRTAP17-1
keratin associated protein 17-1
chr10_+_133753533 0.228 ENST00000422256.2
PPP2R2D
protein phosphatase 2, regulatory subunit B, delta
chr10_-_104262426 0.227 ENST00000487599.1
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr13_+_22245522 0.227 ENST00000382353.5
FGF9
fibroblast growth factor 9
chr6_+_114178512 0.224 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr2_+_173600514 0.222 ENST00000264111.6
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr4_+_144303093 0.221 ENST00000505913.1
GAB1
GRB2-associated binding protein 1
chr12_-_118797475 0.220 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3


TAO kinase 3


chr3_-_37216055 0.219 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr6_+_22146851 0.219 ENST00000606197.1
CASC15
cancer susceptibility candidate 15 (non-protein coding)
chr18_-_60985914 0.219 ENST00000589955.1
BCL2
B-cell CLL/lymphoma 2
chr18_-_33702078 0.218 ENST00000586829.1
SLC39A6
solute carrier family 39 (zinc transporter), member 6
chr17_+_73780852 0.217 ENST00000589666.1
UNK
unkempt family zinc finger
chr2_+_192543153 0.216 ENST00000425611.2
NABP1
nucleic acid binding protein 1
chr2_+_173600565 0.216 ENST00000397081.3
RAPGEF4
Rap guanine nucleotide exchange factor (GEF) 4
chr12_-_91546926 0.211 ENST00000550758.1
DCN
decorin
chr3_+_44690211 0.209 ENST00000396056.2
ENST00000432115.2
ENST00000415571.2
ENST00000399560.2
ENST00000296092.3
ENST00000542250.1
ENST00000453164.1
ZNF35






zinc finger protein 35






chr10_+_80008505 0.206 ENST00000434974.1
ENST00000423770.1
ENST00000432742.1
LINC00856


long intergenic non-protein coding RNA 856


chr7_-_83824169 0.204 ENST00000265362.4
SEMA3A
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A
chr6_-_34639733 0.203 ENST00000374021.1
C6orf106
chromosome 6 open reading frame 106
chr15_-_55541227 0.202 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr6_-_32083106 0.202 ENST00000442721.1
TNXB
tenascin XB
chr5_-_115910630 0.201 ENST00000343348.6
SEMA6A
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr6_+_31105426 0.201 ENST00000547221.1
PSORS1C1
psoriasis susceptibility 1 candidate 1
chr17_-_39191107 0.201 ENST00000344363.5
KRTAP1-3
keratin associated protein 1-3
chr3_-_141747459 0.200 ENST00000477292.1
ENST00000478006.1
ENST00000495310.1
ENST00000486111.1
TFDP2



transcription factor Dp-2 (E2F dimerization partner 2)



chr12_-_81992111 0.196 ENST00000443686.3
ENST00000407050.4
PPFIA2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr17_+_45286706 0.195 ENST00000393450.1
ENST00000572303.1
MYL4

myosin, light chain 4, alkali; atrial, embryonic

chr9_+_95736758 0.194 ENST00000337352.6
FGD3
FYVE, RhoGEF and PH domain containing 3
chr3_+_40498783 0.193 ENST00000338970.6
ENST00000396203.2
ENST00000416518.1
RPL14


ribosomal protein L14


chr5_+_32788945 0.192 ENST00000326958.1
AC026703.1
AC026703.1
chr2_-_183291741 0.189 ENST00000351439.5
ENST00000409365.1
PDE1A

phosphodiesterase 1A, calmodulin-dependent

chr4_+_118955500 0.188 ENST00000296499.5
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr1_+_115572415 0.187 ENST00000256592.1
TSHB
thyroid stimulating hormone, beta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.3 1.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.3 0.9 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.3 0.9 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.2 0.6 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.1 0.4 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.4 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.4 GO:0080154 regulation of fertilization(GO:0080154)
0.1 0.9 GO:0097338 response to clozapine(GO:0097338)
0.1 1.8 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 0.3 GO:0006427 histidyl-tRNA aminoacylation(GO:0006427)
0.1 0.3 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.3 GO:0003358 noradrenergic neuron development(GO:0003358)
0.1 0.8 GO:1903764 regulation of potassium ion export across plasma membrane(GO:1903764)
0.1 0.8 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 0.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.6 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.4 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 0.4 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.1 0.2 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.1 0.7 GO:0035986 senescence-associated heterochromatin focus assembly(GO:0035986)
0.1 0.8 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.1 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.1 1.3 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.1 0.3 GO:0036269 swimming behavior(GO:0036269)
0.1 0.6 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.1 1.3 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.1 0.8 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.1 0.6 GO:0015705 iodide transport(GO:0015705)
0.1 0.8 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.1 1.6 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.2 GO:0010621 negative regulation of transcription by transcription factor localization(GO:0010621)
0.1 0.5 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.1 0.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 1.0 GO:0016102 retinoic acid biosynthetic process(GO:0002138) diterpenoid biosynthetic process(GO:0016102)
0.1 0.2 GO:0044179 hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.5 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.8 GO:0035878 nail development(GO:0035878)
0.1 0.2 GO:0071676 negative regulation of mononuclear cell migration(GO:0071676)
0.1 0.2 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.1 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.2 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.1 0.2 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.2 GO:0048880 sensory system development(GO:0048880)
0.0 0.1 GO:1901207 regulation of heart looping(GO:1901207)
0.0 0.1 GO:0001812 positive regulation of type I hypersensitivity(GO:0001812)
0.0 0.3 GO:2001181 positive regulation of interleukin-10 secretion(GO:2001181)
0.0 0.2 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 0.2 GO:1990637 response to prolactin(GO:1990637)
0.0 0.3 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.3 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.0 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.4 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.0 0.2 GO:0048867 ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867)
0.0 0.3 GO:0046098 guanine metabolic process(GO:0046098)
0.0 0.3 GO:0061669 spontaneous neurotransmitter secretion(GO:0061669) spontaneous synaptic transmission(GO:0098814)
0.0 0.4 GO:0034650 aldosterone metabolic process(GO:0032341) aldosterone biosynthetic process(GO:0032342) cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651)
0.0 0.3 GO:0021615 rhombomere development(GO:0021546) glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.6 GO:0009629 response to gravity(GO:0009629)
0.0 0.8 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.0 0.2 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 1.0 GO:1904380 endoplasmic reticulum mannose trimming(GO:1904380)
0.0 0.1 GO:0042116 macrophage activation(GO:0042116)
0.0 0.2 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051)
0.0 0.3 GO:0038030 non-canonical Wnt signaling pathway via MAPK cascade(GO:0038030) non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.3 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.0 0.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.1 GO:1903936 response to sodium arsenite(GO:1903935) cellular response to sodium arsenite(GO:1903936)
0.0 0.1 GO:0001757 somite specification(GO:0001757) sclerotome development(GO:0061056)
0.0 0.1 GO:0006597 spermine biosynthetic process(GO:0006597)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 3.8 GO:0070268 cornification(GO:0070268)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.2 GO:0021979 hypothalamus cell differentiation(GO:0021979)
0.0 0.2 GO:0098704 fructose transport(GO:0015755) fructose import(GO:0032445) carbohydrate import into cell(GO:0097319) carbohydrate import across plasma membrane(GO:0098704) fructose import across plasma membrane(GO:1990539)
0.0 0.2 GO:0060484 lung-associated mesenchyme development(GO:0060484)
0.0 0.1 GO:2000229 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.7 GO:0009954 proximal/distal pattern formation(GO:0009954)
0.0 0.1 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) regulation of bone mineralization involved in bone maturation(GO:1900157) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.3 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.1 GO:0097476 spinal cord motor neuron migration(GO:0097476)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.2 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.3 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 1.8 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.3 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.6 GO:0048665 neuron fate specification(GO:0048665)
0.0 0.3 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.2 GO:0002447 eosinophil activation involved in immune response(GO:0002278) eosinophil mediated immunity(GO:0002447) eosinophil degranulation(GO:0043308)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0051573 negative regulation of histone H3-K9 methylation(GO:0051573)
0.0 0.7 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.1 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 1.0 GO:0051602 response to electrical stimulus(GO:0051602)
0.0 0.1 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.1 GO:1902227 negative regulation of macrophage colony-stimulating factor signaling pathway(GO:1902227) negative regulation of response to macrophage colony-stimulating factor(GO:1903970) negative regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903973) regulation of microglial cell activation(GO:1903978)
0.0 0.1 GO:0044245 polysaccharide digestion(GO:0044245)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.2 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.1 GO:1990737 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394) response to manganese-induced endoplasmic reticulum stress(GO:1990737)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:0097084 vascular smooth muscle cell development(GO:0097084)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.0 GO:0033024 mast cell homeostasis(GO:0033023) mast cell apoptotic process(GO:0033024) regulation of mast cell apoptotic process(GO:0033025)
0.0 0.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.3 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 0.2 GO:0003183 mitral valve morphogenesis(GO:0003183)
0.0 0.1 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.0 0.0 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.0 0.8 GO:0043268 positive regulation of potassium ion transport(GO:0043268)
0.0 0.3 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.8 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.1 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.4 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.0 0.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.4 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.9 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.7 GO:0097435 fibril organization(GO:0097435)
0.0 0.6 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0000732 strand displacement(GO:0000732)
0.0 0.1 GO:0010579 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.0 0.1 GO:1904352 positive regulation of protein catabolic process in the vacuole(GO:1904352)
0.0 0.2 GO:0030299 intestinal cholesterol absorption(GO:0030299) intestinal lipid absorption(GO:0098856)
0.0 0.1 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.4 GO:0002026 regulation of the force of heart contraction(GO:0002026)
0.0 0.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.3 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.1 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.1 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.5 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.3 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.1 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.1 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.1 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.2 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.1 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0005588 collagen type V trimer(GO:0005588)
0.3 0.8 GO:0033150 cytoskeletal calyx(GO:0033150)
0.3 1.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 0.9 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 0.5 GO:0034676 integrin alpha6-beta4 complex(GO:0034676)
0.1 1.3 GO:0098645 network-forming collagen trimer(GO:0098642) collagen network(GO:0098645)
0.1 0.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.8 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.6 GO:0035976 AP1 complex(GO:0035976)
0.1 0.5 GO:0035692 macrophage migration inhibitory factor receptor complex(GO:0035692)
0.1 0.5 GO:0002177 manchette(GO:0002177)
0.1 1.0 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.7 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.5 GO:0043219 lateral loop(GO:0043219)
0.0 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 1.0 GO:0005922 connexon complex(GO:0005922)
0.0 0.9 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.3 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.0 0.6 GO:0030056 hemidesmosome(GO:0030056)
0.0 2.2 GO:0045095 keratin filament(GO:0045095)
0.0 1.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.1 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.0 1.9 GO:0005882 intermediate filament(GO:0005882)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 1.2 GO:0000786 nucleosome(GO:0000786)
0.0 0.2 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.2 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0010369 chromocenter(GO:0010369)
0.0 0.2 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0045272 plasma membrane respiratory chain complex I(GO:0045272)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0030127 COPII vesicle coat(GO:0030127)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 1.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 0.9 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.4 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 0.8 GO:0042835 BRE binding(GO:0042835)
0.1 0.6 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 0.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.4 GO:0061752 telomeric repeat-containing RNA binding(GO:0061752)
0.1 0.7 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.3 GO:0004821 histidine-tRNA ligase activity(GO:0004821)
0.1 0.5 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.4 GO:0032038 myosin II heavy chain binding(GO:0032038)
0.1 1.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.4 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.1 0.3 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.5 GO:1990254 keratin filament binding(GO:1990254)
0.1 0.5 GO:0050816 phosphoserine binding(GO:0050815) phosphothreonine binding(GO:0050816)
0.1 1.0 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.1 0.5 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.2 GO:0070698 type I activin receptor binding(GO:0070698)
0.1 0.7 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.5 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.3 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.2 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 1.0 GO:0019841 retinol binding(GO:0019841)
0.0 0.4 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.7 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.5 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 1.3 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.9 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.0 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.7 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.3 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 1.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.2 GO:0005353 fructose transmembrane transporter activity(GO:0005353)
0.0 0.2 GO:0004465 lipoprotein lipase activity(GO:0004465)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0004727 prenylated protein tyrosine phosphatase activity(GO:0004727)
0.0 0.1 GO:0017018 myosin phosphatase activity(GO:0017018)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.6 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.4 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.4 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.2 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.2 GO:0070628 proteasome binding(GO:0070628)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.7 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 1.1 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 2.0 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.8 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.5 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.7 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 1.1 PID_EPHRINB_REV_PATHWAY Ephrin B reverse signaling
0.0 0.8 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.7 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 0.5 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.5 PID_NOTCH_PATHWAY Notch signaling pathway
0.0 0.5 PID_BETA_CATENIN_NUC_PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.0 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.9 PID_ENDOTHELIN_PATHWAY Endothelins
0.0 0.9 PID_FGF_PATHWAY FGF signaling pathway
0.0 0.7 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.9 PID_IL12_2PATHWAY IL12-mediated signaling events
0.0 0.1 PID_EPO_PATHWAY EPO signaling pathway
0.0 0.5 PID_ECADHERIN_NASCENT_AJ_PATHWAY E-cadherin signaling in the nascent adherens junction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 1.8 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 1.0 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 1.6 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME_RECYCLING_OF_BILE_ACIDS_AND_SALTS Genes involved in Recycling of bile acids and salts
0.0 3.2 REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION Genes involved in Extracellular matrix organization
0.0 2.3 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.5 REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.6 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 1.4 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.6 REACTOME_IL_7_SIGNALING Genes involved in Interleukin-7 signaling
0.0 1.2 REACTOME_PACKAGING_OF_TELOMERE_ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.5 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.5 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.4 REACTOME_ENDOGENOUS_STEROLS Genes involved in Endogenous sterols
0.0 0.3 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.5 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.5 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.1 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.2 REACTOME_KERATAN_SULFATE_DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.1 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 0.8 REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.3 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME_PD1_SIGNALING Genes involved in PD-1 signaling
0.0 0.2 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion