Motif ID: EGR3_EGR2

Z-value: 0.618

Transcription factors associated with EGR3_EGR2:

Gene SymbolEntrez IDGene Name
EGR2 ENSG00000122877.9 EGR2
EGR3 ENSG00000179388.8 EGR3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
EGR3hg19_v2_chr8_-_22550815_225508440.341.0e-01Click!
EGR2hg19_v2_chr10_-_64576105_64576133-0.155.0e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of EGR3_EGR2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_51472031 1.171 ENST00000391808.1
KLK6
kallikrein-related peptidase 6
chr19_-_51472222 1.083 ENST00000376851.3
KLK6
kallikrein-related peptidase 6
chr15_+_39873268 1.038 ENST00000397591.2
ENST00000260356.5
THBS1

thrombospondin 1

chr1_-_9189229 0.942 ENST00000377411.4
GPR157
G protein-coupled receptor 157
chr5_-_176924562 0.913 ENST00000359895.2
ENST00000355572.2
ENST00000355841.2
ENST00000393551.1
ENST00000505074.1
ENST00000356618.4
ENST00000393546.4
PDLIM7






PDZ and LIM domain 7 (enigma)






chrX_+_130192318 0.885 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr14_-_69445968 0.806 ENST00000438964.2
ACTN1
actinin, alpha 1
chrX_+_130192216 0.756 ENST00000276211.5
ARHGAP36
Rho GTPase activating protein 36
chr18_+_33877654 0.748 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
FHOD3



formin homology 2 domain containing 3



chr6_-_4135825 0.745 ENST00000380118.3
ENST00000413766.2
ENST00000361538.2
ECI2


enoyl-CoA delta isomerase 2


chr10_-_129924611 0.727 ENST00000368654.3
MKI67
marker of proliferation Ki-67
chr14_-_69445793 0.694 ENST00000538545.2
ENST00000394419.4
ACTN1

actinin, alpha 1

chr11_-_125366089 0.687 ENST00000366139.3
ENST00000278919.3
FEZ1

fasciculation and elongation protein zeta 1 (zygin I)

chr15_+_74833518 0.681 ENST00000346246.5
ARID3B
AT rich interactive domain 3B (BRIGHT-like)
chr6_+_43739697 0.680 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr9_+_34989638 0.676 ENST00000453597.3
ENST00000335998.3
ENST00000312316.5
DNAJB5


DnaJ (Hsp40) homolog, subfamily B, member 5


chr8_+_32405728 0.653 ENST00000523079.1
ENST00000338921.4
ENST00000356819.4
ENST00000287845.5
ENST00000341377.5
NRG1




neuregulin 1




chr2_+_30454390 0.647 ENST00000395323.3
ENST00000406087.1
ENST00000404397.1
LBH


limb bud and heart development


chr19_+_44037546 0.646 ENST00000601282.1
ZNF575
zinc finger protein 575
chrX_-_48814810 0.593 ENST00000376488.3
ENST00000396743.3
ENST00000156084.4
OTUD5


OTU domain containing 5


chr2_-_27718052 0.592 ENST00000264703.3
FNDC4
fibronectin type III domain containing 4
chr14_-_69446034 0.583 ENST00000193403.6
ACTN1
actinin, alpha 1
chr8_+_32406179 0.564 ENST00000405005.3
NRG1
neuregulin 1
chr7_+_100770328 0.552 ENST00000223095.4
ENST00000445463.2
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr12_+_70760056 0.551 ENST00000258111.4
KCNMB4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr1_-_94312706 0.545 ENST00000370244.1
BCAR3
breast cancer anti-estrogen resistance 3
chr1_-_35395178 0.534 ENST00000373347.1
DLGAP3
discs, large (Drosophila) homolog-associated protein 3
chr1_+_45205478 0.530 ENST00000452259.1
ENST00000372224.4
KIF2C

kinesin family member 2C

chr16_-_55866997 0.527 ENST00000360526.3
ENST00000361503.4
CES1

carboxylesterase 1

chr1_+_45205498 0.524 ENST00000372218.4
KIF2C
kinesin family member 2C
chr8_+_32405785 0.520 ENST00000287842.3
NRG1
neuregulin 1
chr15_-_80263506 0.484 ENST00000335661.6
BCL2A1
BCL2-related protein A1
chr16_+_46723552 0.454 ENST00000219097.2
ENST00000568364.2
ORC6

origin recognition complex, subunit 6

chr6_+_86159821 0.450 ENST00000369651.3
NT5E
5'-nucleotidase, ecto (CD73)
chr1_-_93426998 0.445 ENST00000370310.4
FAM69A
family with sequence similarity 69, member A
chr6_-_112194484 0.443 ENST00000518295.1
ENST00000484067.2
ENST00000229470.5
ENST00000356013.2
ENST00000368678.4
ENST00000523238.1
ENST00000354650.3
FYN






FYN oncogene related to SRC, FGR, YES






chr19_-_41196534 0.435 ENST00000252891.4
NUMBL
numb homolog (Drosophila)-like
chr11_+_124609742 0.426 ENST00000284292.6
NRGN
neurogranin (protein kinase C substrate, RC3)
chr6_+_30689401 0.425 ENST00000396389.1
ENST00000396384.1
TUBB

tubulin, beta class I

chr4_+_8201091 0.425 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3TC1



SH3 domain and tetratricopeptide repeats 1



chr6_-_4135693 0.418 ENST00000495548.1
ENST00000380125.2
ENST00000465828.1
ECI2


enoyl-CoA delta isomerase 2


chr6_+_30689350 0.417 ENST00000330914.3
TUBB
tubulin, beta class I
chr16_+_11038403 0.415 ENST00000409552.3
CLEC16A
C-type lectin domain family 16, member A
chr17_-_41623691 0.413 ENST00000545954.1
ETV4
ets variant 4
chr11_+_124609823 0.396 ENST00000412681.2
NRGN
neurogranin (protein kinase C substrate, RC3)
chr19_+_34112850 0.394 ENST00000591231.1
ENST00000434302.1
ENST00000438847.3
CHST8


carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8


chr6_+_86159765 0.392 ENST00000369646.3
ENST00000257770.3
NT5E

5'-nucleotidase, ecto (CD73)

chr17_-_4890919 0.391 ENST00000572543.1
ENST00000381311.5
ENST00000348066.3
ENST00000358183.4
CAMTA2



calmodulin binding transcription activator 2



chr4_+_150999418 0.390 ENST00000296550.7
DCLK2
doublecortin-like kinase 2
chr19_+_46144884 0.384 ENST00000593161.1
AC006132.1
chromosome 19 open reading frame 83
chr11_-_64546202 0.383 ENST00000377390.3
ENST00000227503.9
ENST00000377394.3
ENST00000422298.2
ENST00000334944.5
SF1




splicing factor 1




chr19_+_35634146 0.383 ENST00000586063.1
ENST00000270310.2
ENST00000588265.1
FXYD7


FXYD domain containing ion transport regulator 7


chrX_-_43741594 0.377 ENST00000536181.1
ENST00000378069.4
MAOB

monoamine oxidase B

chr16_+_3070313 0.377 ENST00000326577.4
TNFRSF12A
tumor necrosis factor receptor superfamily, member 12A
chr17_-_41623716 0.373 ENST00000319349.5
ETV4
ets variant 4
chr11_-_66725837 0.371 ENST00000393958.2
ENST00000393960.1
ENST00000524491.1
ENST00000355677.3
PC



pyruvate carboxylase



chr19_-_3801789 0.369 ENST00000590849.1
ENST00000395045.2
MATK

megakaryocyte-associated tyrosine kinase

chr2_+_23608064 0.365 ENST00000486442.1
KLHL29
kelch-like family member 29
chr20_+_44035200 0.363 ENST00000372717.1
ENST00000360981.4
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr22_+_21987005 0.362 ENST00000607942.1
ENST00000425975.1
ENST00000292779.3
CCDC116


coiled-coil domain containing 116


chr10_-_43762329 0.361 ENST00000395810.1
RASGEF1A
RasGEF domain family, member 1A
chr19_+_41860047 0.360 ENST00000604123.1
TMEM91
transmembrane protein 91
chr16_+_3070356 0.358 ENST00000341627.5
ENST00000575124.1
ENST00000575836.1
TNFRSF12A


tumor necrosis factor receptor superfamily, member 12A


chr6_-_110501200 0.347 ENST00000392586.1
ENST00000419252.1
ENST00000392589.1
ENST00000392588.1
ENST00000359451.2
WASF1




WAS protein family, member 1




chr6_+_44191290 0.340 ENST00000371755.3
ENST00000371740.5
ENST00000371731.1
ENST00000393841.1
SLC29A1



solute carrier family 29 (equilibrative nucleoside transporter), member 1



chr1_-_6321035 0.332 ENST00000377893.2
GPR153
G protein-coupled receptor 153
chr6_+_99282570 0.331 ENST00000328345.5
POU3F2
POU class 3 homeobox 2
chr1_-_85156216 0.330 ENST00000342203.3
ENST00000370612.4
SSX2IP

synovial sarcoma, X breakpoint 2 interacting protein

chr6_-_110500905 0.329 ENST00000392587.2
WASF1
WAS protein family, member 1
chr17_-_72772462 0.326 ENST00000582870.1
ENST00000581136.1
ENST00000357814.3
ENST00000579218.1
ENST00000583476.1
ENST00000580301.1
ENST00000583757.1
ENST00000582524.1
NAT9







N-acetyltransferase 9 (GCN5-related, putative)







chr16_+_30194916 0.322 ENST00000570045.1
ENST00000565497.1
ENST00000570244.1
CORO1A


coronin, actin binding protein, 1A


chr1_+_107683436 0.318 ENST00000370068.1
NTNG1
netrin G1
chr4_-_82393052 0.316 ENST00000335927.7
ENST00000504863.1
ENST00000264400.2
RASGEF1B


RasGEF domain family, member 1B


chr2_+_204193149 0.314 ENST00000422511.2
ABI2
abl-interactor 2
chr3_-_50541028 0.311 ENST00000266039.3
ENST00000435965.1
ENST00000395083.1
CACNA2D2


calcium channel, voltage-dependent, alpha 2/delta subunit 2


chr13_+_52586517 0.308 ENST00000523764.1
ENST00000521508.1
ALG11

ALG11, alpha-1,2-mannosyltransferase

chr8_+_73449625 0.307 ENST00000523207.1
KCNB2
potassium voltage-gated channel, Shab-related subfamily, member 2
chr9_+_131709966 0.307 ENST00000372577.2
NUP188
nucleoporin 188kDa
chr17_-_4890649 0.305 ENST00000361571.5
CAMTA2
calmodulin binding transcription activator 2
chr19_+_45409011 0.304 ENST00000252486.4
ENST00000446996.1
ENST00000434152.1
APOE


apolipoprotein E


chr9_-_35115836 0.301 ENST00000378566.1
ENST00000378554.2
ENST00000322813.5
FAM214B


family with sequence similarity 214, member B


chr16_-_2264779 0.293 ENST00000333503.7
PGP
phosphoglycolate phosphatase
chr16_-_402639 0.293 ENST00000262320.3
AXIN1
axin 1
chr7_-_93520259 0.291 ENST00000222543.5
TFPI2
tissue factor pathway inhibitor 2
chr2_+_110371905 0.289 ENST00000356454.3
SOWAHC
sosondowah ankyrin repeat domain family member C
chr3_+_123813543 0.288 ENST00000360013.3
KALRN
kalirin, RhoGEF kinase
chrX_-_48814278 0.286 ENST00000455452.1
OTUD5
OTU domain containing 5
chr6_-_31088214 0.286 ENST00000376288.2
CDSN
corneodesmosin
chr12_+_66217911 0.284 ENST00000403681.2
HMGA2
high mobility group AT-hook 2
chr3_-_171178157 0.281 ENST00000465393.1
ENST00000436636.2
ENST00000369326.5
ENST00000538048.1
ENST00000341852.6
TNIK




TRAF2 and NCK interacting kinase




chr4_-_175443788 0.281 ENST00000541923.1
HPGD
hydroxyprostaglandin dehydrogenase 15-(NAD)
chr1_+_23695680 0.277 ENST00000454117.1
ENST00000335648.3
ENST00000518821.1
ENST00000437367.2
C1orf213



chromosome 1 open reading frame 213



chr17_-_42907564 0.277 ENST00000592524.1
GJC1
gap junction protein, gamma 1, 45kDa
chr2_-_177502254 0.276 ENST00000339037.3
AC017048.3
long intergenic non-protein coding RNA 1116
chr2_+_191745560 0.275 ENST00000338435.4
GLS
glutaminase
chr2_+_73441350 0.274 ENST00000389501.4
SMYD5
SMYD family member 5
chr3_-_50540854 0.267 ENST00000423994.2
ENST00000424201.2
ENST00000479441.1
ENST00000429770.1
CACNA2D2



calcium channel, voltage-dependent, alpha 2/delta subunit 2



chr2_+_204193129 0.267 ENST00000417864.1
ABI2
abl-interactor 2
chr1_-_160040038 0.266 ENST00000368089.3
KCNJ10
potassium inwardly-rectifying channel, subfamily J, member 10
chr9_-_101017900 0.262 ENST00000375066.5
TBC1D2
TBC1 domain family, member 2
chr1_-_85156090 0.257 ENST00000605755.1
ENST00000437941.2
SSX2IP

synovial sarcoma, X breakpoint 2 interacting protein

chr14_+_65171099 0.256 ENST00000247226.7
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chrX_+_133930798 0.254 ENST00000414371.2
FAM122C
family with sequence similarity 122C
chr8_-_127570603 0.251 ENST00000304916.3
FAM84B
family with sequence similarity 84, member B
chr3_-_149688896 0.251 ENST00000239940.7
PFN2
profilin 2
chr16_+_25703274 0.251 ENST00000331351.5
HS3ST4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr19_-_13617037 0.248 ENST00000360228.5
CACNA1A
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr19_-_41859814 0.245 ENST00000221930.5
TGFB1
transforming growth factor, beta 1
chr11_-_64545941 0.244 ENST00000377387.1
SF1
splicing factor 1
chr3_-_124774802 0.243 ENST00000311127.4
HEG1
heart development protein with EGF-like domains 1
chr11_-_18813110 0.243 ENST00000396168.1
PTPN5
protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)
chr2_-_42721110 0.243 ENST00000394973.4
ENST00000306078.1
KCNG3

potassium voltage-gated channel, subfamily G, member 3

chr12_-_109125285 0.243 ENST00000552871.1
ENST00000261401.3
CORO1C

coronin, actin binding protein, 1C

chr11_-_65325203 0.242 ENST00000526927.1
ENST00000536982.1
LTBP3

latent transforming growth factor beta binding protein 3

chr4_-_175443484 0.242 ENST00000514584.1
ENST00000542498.1
ENST00000296521.7
ENST00000422112.2
ENST00000504433.1
HPGD




hydroxyprostaglandin dehydrogenase 15-(NAD)




chr1_-_203055129 0.240 ENST00000241651.4
MYOG
myogenin (myogenic factor 4)
chr2_+_220306745 0.239 ENST00000431523.1
ENST00000396698.1
ENST00000396695.2
SPEG


SPEG complex locus


chr11_-_65325664 0.239 ENST00000301873.5
LTBP3
latent transforming growth factor beta binding protein 3
chr10_-_103535657 0.238 ENST00000344255.3
ENST00000320185.2
ENST00000346714.3
ENST00000347978.2
FGF8



fibroblast growth factor 8 (androgen-induced)



chr13_-_38443860 0.236 ENST00000426868.2
ENST00000379681.3
ENST00000338947.5
ENST00000355779.2
ENST00000358477.2
ENST00000379673.2
TRPC4





transient receptor potential cation channel, subfamily C, member 4





chr17_+_79008940 0.235 ENST00000392411.3
ENST00000575989.1
ENST00000321280.7
ENST00000428708.2
ENST00000575712.1
ENST00000575245.1
ENST00000435091.3
ENST00000321300.6
BAIAP2







BAI1-associated protein 2







chr8_-_124408652 0.235 ENST00000287394.5
ATAD2
ATPase family, AAA domain containing 2
chr4_+_145567297 0.234 ENST00000434550.2
HHIP
hedgehog interacting protein
chr10_-_135150367 0.233 ENST00000368555.3
ENST00000252939.4
ENST00000368558.1
ENST00000368556.2
CALY



calcyon neuron-specific vesicular protein



chrX_+_21958674 0.231 ENST00000404933.2
SMS
spermine synthase
chr7_-_93520191 0.231 ENST00000545378.1
TFPI2
tissue factor pathway inhibitor 2
chr15_-_83316711 0.230 ENST00000568128.1
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr6_-_109777128 0.230 ENST00000358807.3
ENST00000358577.3
MICAL1

microtubule associated monooxygenase, calponin and LIM domain containing 1

chrX_+_21958814 0.229 ENST00000379404.1
ENST00000415881.2
SMS

spermine synthase

chr14_+_65171315 0.229 ENST00000394691.1
PLEKHG3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr1_+_65886326 0.228 ENST00000371059.3
ENST00000371060.3
ENST00000349533.6
ENST00000406510.3
LEPR



leptin receptor



chr16_+_23847339 0.226 ENST00000303531.7
PRKCB
protein kinase C, beta
chr5_-_115177247 0.224 ENST00000500945.2
ATG12
autophagy related 12
chr5_-_176923846 0.223 ENST00000506537.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr3_-_50340996 0.223 ENST00000266031.4
ENST00000395143.2
ENST00000457214.2
ENST00000447605.2
ENST00000418723.1
ENST00000395144.2
HYAL1





hyaluronoglucosaminidase 1





chr17_+_7210921 0.222 ENST00000573542.1
EIF5A
eukaryotic translation initiation factor 5A
chr18_-_47340297 0.221 ENST00000586485.1
ENST00000587994.1
ENST00000586100.1
ENST00000285093.10
ACAA2



acetyl-CoA acyltransferase 2



chr19_+_41882466 0.219 ENST00000436170.2
TMEM91
transmembrane protein 91
chr10_+_99473455 0.218 ENST00000285605.6
MARVELD1
MARVEL domain containing 1
chrX_+_67913471 0.218 ENST00000374597.3
STARD8
StAR-related lipid transfer (START) domain containing 8
chr14_-_100842588 0.216 ENST00000556645.1
ENST00000556209.1
ENST00000556504.1
ENST00000556435.1
ENST00000554772.1
ENST00000553581.1
ENST00000553769.2
ENST00000554605.1
ENST00000557722.1
ENST00000553413.1
ENST00000553524.1
ENST00000358655.4
WARS











tryptophanyl-tRNA synthetase











chr10_+_7745303 0.215 ENST00000429820.1
ENST00000379587.4
ITIH2

inter-alpha-trypsin inhibitor heavy chain 2

chr7_+_45039783 0.215 ENST00000258781.6
ENST00000541586.1
ENST00000544363.1
CCM2


cerebral cavernous malformation 2


chr9_-_103115185 0.215 ENST00000374902.4
TEX10
testis expressed 10
chr20_+_44034676 0.214 ENST00000372723.3
ENST00000372722.3
DBNDD2

dysbindin (dystrobrevin binding protein 1) domain containing 2

chr11_+_119076745 0.213 ENST00000264033.4
CBL
Cbl proto-oncogene, E3 ubiquitin protein ligase
chr19_-_41196458 0.213 ENST00000598779.1
NUMBL
numb homolog (Drosophila)-like
chr2_-_9143786 0.213 ENST00000462696.1
ENST00000305997.3
MBOAT2

membrane bound O-acyltransferase domain containing 2

chr5_-_33892046 0.213 ENST00000352040.3
ADAMTS12
ADAM metallopeptidase with thrombospondin type 1 motif, 12
chrX_-_47479246 0.211 ENST00000295987.7
ENST00000340666.4
SYN1

synapsin I

chr14_-_75079026 0.208 ENST00000261978.4
LTBP2
latent transforming growth factor beta binding protein 2
chr16_-_56459354 0.208 ENST00000290649.5
AMFR
autocrine motility factor receptor, E3 ubiquitin protein ligase
chr7_+_86274145 0.208 ENST00000439827.1
ENST00000394720.2
ENST00000421579.1
GRM3


glutamate receptor, metabotropic 3


chr7_+_143078652 0.205 ENST00000354434.4
ENST00000449423.2
ZYX

zyxin

chr22_-_37915535 0.204 ENST00000403299.1
CARD10
caspase recruitment domain family, member 10
chr11_-_65325430 0.202 ENST00000322147.4
LTBP3
latent transforming growth factor beta binding protein 3
chr15_-_78933567 0.200 ENST00000261751.3
ENST00000412074.2
CHRNB4

cholinergic receptor, nicotinic, beta 4 (neuronal)

chr11_-_18813353 0.200 ENST00000358540.2
ENST00000396171.4
ENST00000396167.2
PTPN5


protein tyrosine phosphatase, non-receptor type 5 (striatum-enriched)


chr17_+_7211280 0.199 ENST00000419711.2
ENST00000571955.1
ENST00000573714.1
EIF5A


eukaryotic translation initiation factor 5A


chr12_-_57634475 0.199 ENST00000393825.1
NDUFA4L2
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr15_+_80696666 0.196 ENST00000303329.4
ARNT2
aryl-hydrocarbon receptor nuclear translocator 2
chr1_-_111217603 0.195 ENST00000369769.2
KCNA3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr2_+_69001913 0.195 ENST00000409030.3
ENST00000409220.1
ARHGAP25

Rho GTPase activating protein 25

chr1_-_110283138 0.193 ENST00000256594.3
GSTM3
glutathione S-transferase mu 3 (brain)
chr2_-_177502659 0.193 ENST00000295549.4
AC017048.3
long intergenic non-protein coding RNA 1116
chr20_-_41818373 0.193 ENST00000373187.1
ENST00000356100.2
ENST00000373184.1
ENST00000373190.1
PTPRT



protein tyrosine phosphatase, receptor type, T



chr17_+_7210852 0.193 ENST00000576930.1
EIF5A
eukaryotic translation initiation factor 5A
chr1_+_26606608 0.192 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr19_+_50180317 0.192 ENST00000534465.1
PRMT1
protein arginine methyltransferase 1
chr6_+_31543334 0.191 ENST00000449264.2
TNF
tumor necrosis factor
chr4_-_90758227 0.191 ENST00000506691.1
ENST00000394986.1
ENST00000506244.1
ENST00000394989.2
ENST00000394991.3
SNCA




synuclein, alpha (non A4 component of amyloid precursor)




chr22_+_37956453 0.190 ENST00000249014.4
CDC42EP1
CDC42 effector protein (Rho GTPase binding) 1
chr9_-_132515302 0.190 ENST00000340607.4
PTGES
prostaglandin E synthase
chr1_-_179198702 0.190 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr19_-_54693521 0.189 ENST00000391754.1
ENST00000245615.1
ENST00000431666.2
MBOAT7


membrane bound O-acyltransferase domain containing 7


chr17_+_75369167 0.188 ENST00000423034.2
SEPT9
septin 9
chr5_-_176923803 0.188 ENST00000506161.1
PDLIM7
PDZ and LIM domain 7 (enigma)
chr7_-_92463210 0.187 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr2_-_30144432 0.185 ENST00000389048.3
ALK
anaplastic lymphoma receptor tyrosine kinase
chr16_+_31191431 0.184 ENST00000254108.7
ENST00000380244.3
ENST00000568685.1
FUS


fused in sarcoma


chr17_-_7155274 0.183 ENST00000318988.6
ENST00000575783.1
ENST00000573600.1
CTDNEP1


CTD nuclear envelope phosphatase 1


chr4_-_82393009 0.183 ENST00000436139.2
RASGEF1B
RasGEF domain family, member 1B
chr10_-_103599591 0.182 ENST00000348850.5
KCNIP2
Kv channel interacting protein 2
chr12_-_54785074 0.181 ENST00000338010.5
ENST00000550774.1
ZNF385A

zinc finger protein 385A

chr2_-_220408430 0.180 ENST00000243776.6
CHPF
chondroitin polymerizing factor
chr19_-_51568324 0.180 ENST00000595547.1
ENST00000335422.3
ENST00000595793.1
ENST00000596955.1
KLK13



kallikrein-related peptidase 13



chr1_-_155948218 0.178 ENST00000313667.4
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr7_+_153749732 0.178 ENST00000377770.3
DPP6
dipeptidyl-peptidase 6
chr5_-_16936340 0.178 ENST00000507288.1
ENST00000513610.1
MYO10

myosin X

chr2_+_219433281 0.177 ENST00000273064.6
ENST00000509807.2
ENST00000542068.1
RQCD1


RCD1 required for cell differentiation1 homolog (S. pombe)


chr11_+_35639735 0.177 ENST00000317811.4
FJX1
four jointed box 1 (Drosophila)
chrX_-_46618490 0.176 ENST00000328306.4
SLC9A7
solute carrier family 9, subfamily A (NHE7, cation proton antiporter 7), member 7
chr13_-_77460525 0.176 ENST00000377474.2
ENST00000317765.2
KCTD12

potassium channel tetramerization domain containing 12

chr2_+_228337079 0.175 ENST00000409315.1
ENST00000373671.3
ENST00000409171.1
AGFG1


ArfGAP with FG repeats 1


chr21_-_47648665 0.175 ENST00000450351.1
ENST00000522411.1
ENST00000356396.4
ENST00000397728.3
ENST00000457828.2
LSS




lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)




chr8_-_145331153 0.175 ENST00000377412.4
KM-PA-2
KM-PA-2 protein; Uncharacterized protein
chr19_+_39971505 0.172 ENST00000544017.1
TIMM50
translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae)
chr11_-_32456891 0.172 ENST00000452863.3
WT1
Wilms tumor 1
chr1_+_107682629 0.170 ENST00000370074.4
ENST00000370073.2
ENST00000370071.2
ENST00000542803.1
ENST00000370061.3
ENST00000370072.3
ENST00000370070.2
NTNG1






netrin G1






chr19_+_17666403 0.170 ENST00000252599.4
COLGALT1
collagen beta(1-O)galactosyltransferase 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.3 1.9 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.2 0.7 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 0.6 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.2 0.8 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.2 0.6 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 2.9 GO:0051639 actin filament network formation(GO:0051639)
0.2 0.7 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.2 0.5 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.2 0.5 GO:0006597 spermine biosynthetic process(GO:0006597)
0.1 0.4 GO:0060823 canonical Wnt signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060823)
0.1 1.5 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.5 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.1 0.7 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.6 GO:1904674 positive regulation of somatic stem cell population maintenance(GO:1904674)
0.1 0.4 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.5 GO:0031052 mesodermal-endodermal cell signaling(GO:0003131) programmed DNA elimination(GO:0031049) chromosome breakage(GO:0031052) histone H2A-S139 phosphorylation(GO:0035978) positive regulation of cellular response to X-ray(GO:2000685)
0.1 0.5 GO:0003335 corneocyte development(GO:0003335)
0.1 1.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 2.4 GO:0016540 protein autoprocessing(GO:0016540)
0.1 0.4 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
0.1 0.5 GO:0015862 uridine transport(GO:0015862)
0.1 0.3 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.8 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0032185 septin cytoskeleton organization(GO:0032185)
0.1 0.5 GO:0072301 regulation of metanephric glomerular mesangial cell proliferation(GO:0072301)
0.1 0.6 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.1 0.4 GO:0086021 SA node cell to atrial cardiac muscle cell communication by electrical coupling(GO:0086021)
0.1 0.4 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.3 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.1 0.1 GO:0009996 negative regulation of cell fate specification(GO:0009996)
0.1 0.2 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379)
0.1 0.2 GO:0052553 induction by symbiont of host defense response(GO:0044416) induction of host immune response by virus(GO:0046730) active induction of host immune response by virus(GO:0046732) modulation by symbiont of host defense response(GO:0052031) induction by organism of defense response of other organism involved in symbiotic interaction(GO:0052251) modulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052255) positive regulation by symbiont of host defense response(GO:0052509) positive regulation by organism of defense response of other organism involved in symbiotic interaction(GO:0052510) modulation by organism of immune response of other organism involved in symbiotic interaction(GO:0052552) modulation by symbiont of host immune response(GO:0052553) modulation by virus of host immune response(GO:0075528)
0.1 0.7 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.2 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.1 0.2 GO:0060129 mesodermal cell migration(GO:0008078) thyroid-stimulating hormone-secreting cell differentiation(GO:0060129)
0.1 0.2 GO:0019417 sulfur oxidation(GO:0019417)
0.1 0.7 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 0.3 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.1 0.3 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.1 0.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.1 0.3 GO:1903285 negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) regulation of peroxidase activity(GO:2000468) positive regulation of peroxidase activity(GO:2000470)
0.1 0.3 GO:1902162 mRNA localization resulting in posttranscriptional regulation of gene expression(GO:0010609) regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162) positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902164)
0.1 0.2 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.1 0.2 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.1 0.1 GO:1990535 neuron projection maintenance(GO:1990535)
0.1 0.3 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.4 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.1 0.2 GO:0060557 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874) negative regulation of alkaline phosphatase activity(GO:0010693) positive regulation of translational initiation by iron(GO:0045994) positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) positive regulation of superoxide dismutase activity(GO:1901671) positive regulation of removal of superoxide radicals(GO:1904833)
0.1 0.1 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.1 0.5 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.3 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 0.9 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.1 0.3 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.1 0.2 GO:1903519 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.1 0.2 GO:0031630 regulation of synaptic vesicle fusion to presynaptic membrane(GO:0031630)
0.1 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.4 GO:0030167 proteoglycan catabolic process(GO:0030167)
0.1 0.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 0.2 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.6 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.1 GO:0060913 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) cardiac cell fate determination(GO:0060913)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0007070 negative regulation of transcription during mitosis(GO:0007068) negative regulation of transcription from RNA polymerase II promoter during mitosis(GO:0007070)
0.0 0.4 GO:0014063 negative regulation of serotonin secretion(GO:0014063) positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.0 0.2 GO:1905232 cellular response to L-glutamate(GO:1905232)
0.0 0.1 GO:0061054 dermatome development(GO:0061054) regulation of dermatome development(GO:0061183)
0.0 0.3 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.2 GO:0036269 swimming behavior(GO:0036269)
0.0 0.1 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.0 0.2 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 0.2 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 1.2 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.3 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.1 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.0 0.5 GO:0021859 pyramidal neuron differentiation(GO:0021859) pyramidal neuron development(GO:0021860)
0.0 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.2 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.0 0.1 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.1 GO:0006423 cysteinyl-tRNA aminoacylation(GO:0006423)
0.0 0.1 GO:1903984 regulation of TRAIL-activated apoptotic signaling pathway(GO:1903121) positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.2 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.7 GO:0035020 regulation of Rac protein signal transduction(GO:0035020)
0.0 0.3 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.2 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.0 0.3 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.9 GO:1900273 positive regulation of long-term synaptic potentiation(GO:1900273)
0.0 0.6 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.1 GO:1901895 regulation of interleukin-18 production(GO:0032661) positive regulation of interferon-alpha biosynthetic process(GO:0045356) negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.0 0.1 GO:0048250 mitochondrial iron ion transport(GO:0048250)
0.0 0.1 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.0 0.1 GO:0060380 regulation of single-stranded telomeric DNA binding(GO:0060380) positive regulation of single-stranded telomeric DNA binding(GO:0060381)
0.0 0.2 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.0 0.2 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0018057 peptidyl-lysine oxidation(GO:0018057)
0.0 0.1 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.1 GO:0044026 DNA hypermethylation(GO:0044026)
0.0 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.3 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.1 GO:0048936 peripheral nervous system neuron axonogenesis(GO:0048936)
0.0 0.2 GO:0048845 venous blood vessel morphogenesis(GO:0048845)
0.0 0.1 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.3 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.1 GO:0033625 positive regulation of integrin activation(GO:0033625) positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.3 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415) positive regulation of myoblast proliferation(GO:2000288)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.4 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.4 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.0 0.8 GO:0014887 muscle hypertrophy in response to stress(GO:0003299) cardiac muscle adaptation(GO:0014887) cardiac muscle hypertrophy in response to stress(GO:0014898)
0.0 0.1 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804) negative regulation of neurotrophin production(GO:0032900) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.1 GO:0042137 sequestering of neurotransmitter(GO:0042137)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.0 0.2 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.3 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:1902303 regulation of heart rate by hormone(GO:0003064) negative regulation of potassium ion export(GO:1902303)
0.0 0.1 GO:0021592 fourth ventricle development(GO:0021592)
0.0 0.2 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.0 GO:0032487 regulation of Rap protein signal transduction(GO:0032487)
0.0 0.1 GO:0003383 apical constriction(GO:0003383)
0.0 0.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.0 GO:0021586 pons maturation(GO:0021586)
0.0 0.1 GO:0071484 response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484)
0.0 0.1 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.1 GO:0070221 sulfide oxidation(GO:0019418) sulfide oxidation, using sulfide:quinone oxidoreductase(GO:0070221)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.0 0.2 GO:0046874 quinolinate metabolic process(GO:0046874) pyridine-containing compound catabolic process(GO:0072526)
0.0 0.1 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.1 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.1 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.0 GO:0038162 erythropoietin-mediated signaling pathway(GO:0038162)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.2 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 0.5 GO:0071498 cellular response to fluid shear stress(GO:0071498)
0.0 0.1 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.1 GO:0072103 glomerulus vasculature morphogenesis(GO:0072103) glomerular capillary formation(GO:0072104)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.0 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241) positive regulation of RNA export from nucleus(GO:0046833)
0.0 0.2 GO:1902600 hydrogen ion transmembrane transport(GO:1902600)
0.0 0.1 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.1 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0038060 nitric oxide-cGMP-mediated signaling pathway(GO:0038060)
0.0 0.1 GO:0010286 heat acclimation(GO:0010286) cellular heat acclimation(GO:0070370)
0.0 0.0 GO:2000053 regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.0 GO:2000566 positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.0 0.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.3 GO:0032515 negative regulation of phosphoprotein phosphatase activity(GO:0032515)
0.0 0.0 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0036486 trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486)
0.0 0.2 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.1 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 0.1 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.3 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.1 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725) negative regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072308)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.0 0.1 GO:1905049 negative regulation of metallopeptidase activity(GO:1905049)
0.0 0.1 GO:0035897 proteolysis in other organism(GO:0035897)
0.0 0.1 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.1 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.1 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100)
0.0 0.2 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.1 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.0 0.1 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.0 GO:2000824 negative regulation of androgen receptor activity(GO:2000824)
0.0 0.0 GO:0090263 positive regulation of canonical Wnt signaling pathway(GO:0090263)
0.0 0.1 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)
0.0 0.1 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.9 GO:0042267 natural killer cell mediated cytotoxicity(GO:0042267)
0.0 0.1 GO:0032364 oxygen homeostasis(GO:0032364)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0071104 response to interleukin-9(GO:0071104)
0.0 0.2 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.0 GO:0036363 transforming growth factor beta activation(GO:0036363)
0.0 0.1 GO:0039663 fusion of virus membrane with host plasma membrane(GO:0019064) membrane fusion involved in viral entry into host cell(GO:0039663) multi-organism membrane fusion(GO:0044800)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.0 GO:0090170 trachea formation(GO:0060440) regulation of Golgi inheritance(GO:0090170)
0.0 0.1 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.1 GO:0051414 response to cortisol(GO:0051414)
0.0 0.2 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.0 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.7 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.1 GO:0071107 response to parathyroid hormone(GO:0071107)
0.0 0.8 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.1 GO:0045137 development of primary sexual characteristics(GO:0045137)
0.0 0.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.1 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.1 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.0 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.0 0.0 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701) regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.1 GO:0070070 proton-transporting V-type ATPase complex assembly(GO:0070070) proton-transporting two-sector ATPase complex assembly(GO:0070071) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.3 GO:0040036 regulation of fibroblast growth factor receptor signaling pathway(GO:0040036)
0.0 0.4 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.0 GO:0031291 Ran protein signal transduction(GO:0031291)
0.0 0.2 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 GO:0005916 fascia adherens(GO:0005916)
0.1 0.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 1.4 GO:0031209 SCAR complex(GO:0031209)
0.1 0.1 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.1 1.0 GO:0044327 dendritic spine head(GO:0044327)
0.1 0.3 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.9 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.0 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 0.8 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.1 GO:0044305 calyx of Held(GO:0044305)
0.1 0.1 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.3 GO:0042643 actomyosin, actin portion(GO:0042643)
0.1 0.3 GO:0032449 CBM complex(GO:0032449)
0.1 0.2 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.1 0.4 GO:0031415 NatA complex(GO:0031415)
0.0 0.0 GO:0043679 axon terminus(GO:0043679)
0.0 0.1 GO:0030849 Y chromosome(GO:0000806) autosome(GO:0030849)
0.0 0.3 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 1.9 GO:0030673 axolemma(GO:0030673)
0.0 0.5 GO:0016600 flotillin complex(GO:0016600)
0.0 0.5 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 1.2 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.1 GO:0032002 interleukin-28 receptor complex(GO:0032002)
0.0 0.3 GO:0070081 clathrin-sculpted monoamine transport vesicle(GO:0070081) clathrin-sculpted monoamine transport vesicle membrane(GO:0070083)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 2.8 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.0 GO:0044308 axonal spine(GO:0044308)
0.0 0.1 GO:0005797 Golgi medial cisterna(GO:0005797)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 1.9 GO:0043195 terminal bouton(GO:0043195)
0.0 0.1 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 1.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0005587 collagen type IV trimer(GO:0005587)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0030897 HOPS complex(GO:0030897)
0.0 1.1 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 2.0 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.1 GO:0072589 box H/ACA scaRNP complex(GO:0072589) box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0005883 neurofilament(GO:0005883)
0.0 0.2 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.3 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.0 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.0 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.7 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 0.1 GO:0098839 postsynaptic density membrane(GO:0098839)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0070052 collagen V binding(GO:0070052)
0.3 1.2 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.2 1.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 0.7 GO:0016404 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404)
0.1 0.5 GO:0035501 MH1 domain binding(GO:0035501)
0.1 0.7 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.4 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
0.1 0.5 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 1.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.1 0.3 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.3 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.4 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.1 0.3 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.5 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.1 0.4 GO:0086020 gap junction channel activity involved in SA node cell-atrial cardiac muscle cell electrical coupling(GO:0086020)
0.1 0.4 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.3 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 2.1 GO:0017166 vinculin binding(GO:0017166)
0.1 0.4 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.2 GO:0017130 poly(C) RNA binding(GO:0017130)
0.1 0.3 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.1 0.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.1 0.3 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.4 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.1 0.4 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640) G-protein coupled glutamate receptor activity(GO:0098988)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.2 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.0 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.3 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.2 GO:0050211 procollagen galactosyltransferase activity(GO:0050211)
0.0 0.2 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.8 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0004461 lactose synthase activity(GO:0004461)
0.0 0.1 GO:0004817 cysteine-tRNA ligase activity(GO:0004817)
0.0 0.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.3 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.5 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.4 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.4 GO:0047144 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144)
0.0 1.0 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.8 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0003974 UDP-N-acetylglucosamine 4-epimerase activity(GO:0003974) UDP-glucose 4-epimerase activity(GO:0003978)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0097108 hedgehog family protein binding(GO:0097108)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.5 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.9 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.2 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.2 GO:0004873 asialoglycoprotein receptor activity(GO:0004873)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.5 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0099529 neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential(GO:0099529) transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1904315)
0.0 0.1 GO:0039552 RIG-I binding(GO:0039552)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.1 GO:0004102 choline O-acetyltransferase activity(GO:0004102)
0.0 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.7 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.2 GO:0060002 plus-end directed microfilament motor activity(GO:0060002)
0.0 0.4 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0086062 voltage-gated sodium channel activity involved in Purkinje myocyte action potential(GO:0086062)
0.0 0.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.0 0.1 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.0 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) phosphatidylserine decarboxylase activity(GO:0004609) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.1 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 1.1 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.1 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.0 GO:0008267 poly-glutamine tract binding(GO:0008267)
0.0 0.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.5 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.6 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.2 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0015266 protein channel activity(GO:0015266)
0.0 0.4 GO:0036041 long-chain fatty acid binding(GO:0036041)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.0 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.1 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0016520 growth hormone-releasing hormone receptor activity(GO:0016520)
0.0 0.3 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.2 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.3 GO:0008187 poly-pyrimidine tract binding(GO:0008187)
0.0 0.0 GO:0005298 proline:sodium symporter activity(GO:0005298)
0.0 0.2 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0030226 apolipoprotein receptor activity(GO:0030226) lipoprotein transporter activity(GO:0042954)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.3 PID_SYNDECAN_4_PATHWAY Syndecan-4-mediated signaling events
0.1 3.4 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.1 3.0 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling
0.0 0.3 PID_ECADHERIN_KERATINOCYTE_PATHWAY E-cadherin signaling in keratinocytes
0.0 1.6 SIG_REGULATION_OF_THE_ACTIN_CYTOSKELETON_BY_RHO_GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.2 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 0.4 PID_ARF6_DOWNSTREAM_PATHWAY Arf6 downstream pathway
0.0 0.6 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.4 PID_PRL_SIGNALING_EVENTS_PATHWAY Signaling events mediated by PRL
0.0 0.9 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 0.0 PID_ER_NONGENOMIC_PATHWAY Plasma membrane estrogen receptor signaling
0.0 1.2 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 0.7 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.8 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.6 PID_UPA_UPAR_PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.8 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 PID_RXR_VDR_PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 1.0 PID_LKB1_PATHWAY LKB1 signaling events
0.0 0.2 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.6 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 0.1 SA_TRKA_RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.1 0.8 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 1.9 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.5 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.3 REACTOME_KINESINS Genes involved in Kinesins
0.0 0.7 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PE Genes involved in Acyl chain remodelling of PE
0.0 0.3 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.9 REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.2 REACTOME_SIGNALING_BY_FGFR3_MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.4 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.1 REACTOME_SHC_RELATED_EVENTS Genes involved in SHC-related events
0.0 1.0 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME_HIGHLY_CALCIUM_PERMEABLE_POSTSYNAPTIC_NICOTINIC_ACETYLCHOLINE_RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.1 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.0 0.3 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.1 REACTOME_BINDING_AND_ENTRY_OF_HIV_VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.2 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.3 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.7 REACTOME_SIGNALING_BY_ROBO_RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.4 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.2 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.6 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PI Genes involved in Acyl chain remodelling of PI
0.0 0.3 REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.0 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.3 REACTOME_PKA_MEDIATED_PHOSPHORYLATION_OF_CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.6 REACTOME_BMAL1_CLOCK_NPAS2_ACTIVATES_CIRCADIAN_EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 2.4 REACTOME_SIGNALING_BY_RHO_GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME_TRANSPORT_OF_RIBONUCLEOPROTEINS_INTO_THE_HOST_NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.3 REACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.3 REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.3 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION_IN_THE_MEDIAL_TRANS_GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.2 REACTOME_AKT_PHOSPHORYLATES_TARGETS_IN_THE_CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.1 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12