Motif ID: EN1_ESX1_GBX1

Z-value: 0.524

Transcription factors associated with EN1_ESX1_GBX1:

Gene SymbolEntrez IDGene Name
EN1 ENSG00000163064.6 EN1
ESX1 ENSG00000123576.5 ESX1
GBX1 ENSG00000164900.4 GBX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GBX1hg19_v2_chr7_-_150864635_150864785-0.433.7e-02Click!
EN1hg19_v2_chr2_-_119605253_119605264-0.135.4e-01Click!
ESX1hg19_v2_chrX_-_103499602_103499617-0.096.6e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of EN1_ESX1_GBX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_169013666 1.222 ENST00000359299.3
ANXA10
annexin A10
chr5_+_135394840 1.030 ENST00000503087.1
TGFBI
transforming growth factor, beta-induced, 68kDa
chr17_+_59489112 0.992 ENST00000335108.2
C17orf82
chromosome 17 open reading frame 82
chr12_-_28122980 0.977 ENST00000395868.3
ENST00000534890.1
PTHLH

parathyroid hormone-like hormone

chr5_+_31193847 0.971 ENST00000514738.1
ENST00000265071.2
CDH6

cadherin 6, type 2, K-cadherin (fetal kidney)

chr17_-_39211463 0.948 ENST00000542910.1
ENST00000398477.1
KRTAP2-2

keratin associated protein 2-2

chr12_-_89746173 0.845 ENST00000308385.6
DUSP6
dual specificity phosphatase 6
chr12_-_28123206 0.790 ENST00000542963.1
ENST00000535992.1
PTHLH

parathyroid hormone-like hormone

chr20_+_3776371 0.786 ENST00000245960.5
CDC25B
cell division cycle 25B
chr12_-_10978957 0.781 ENST00000240619.2
TAS2R10
taste receptor, type 2, member 10
chr5_+_52776228 0.730 ENST00000256759.3
FST
follistatin
chr2_+_158114051 0.710 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr1_+_209878182 0.638 ENST00000367027.3
HSD11B1
hydroxysteroid (11-beta) dehydrogenase 1
chrX_-_153602991 0.630 ENST00000369850.3
ENST00000422373.1
FLNA

filamin A, alpha

chr11_-_121986923 0.610 ENST00000560104.1
BLID
BH3-like motif containing, cell death inducer
chr6_+_130339710 0.594 ENST00000526087.1
ENST00000533560.1
ENST00000361794.2
L3MBTL3


l(3)mbt-like 3 (Drosophila)


chr5_+_52776449 0.577 ENST00000396947.3
FST
follistatin
chr12_+_107712173 0.567 ENST00000280758.5
ENST00000420571.2
BTBD11

BTB (POZ) domain containing 11

chr4_-_57547870 0.551 ENST00000381260.3
ENST00000420433.1
ENST00000554144.1
ENST00000557328.1
HOPX



HOP homeobox



chr4_-_57547454 0.544 ENST00000556376.2
HOPX
HOP homeobox
chr18_-_31803169 0.538 ENST00000590712.1
NOL4
nucleolar protein 4
chr2_+_171034646 0.521 ENST00000409044.3
ENST00000408978.4
MYO3B

myosin IIIB

chr7_+_77428066 0.505 ENST00000422959.2
ENST00000307305.8
ENST00000424760.1
PHTF2


putative homeodomain transcription factor 2


chr2_-_208031943 0.476 ENST00000421199.1
ENST00000457962.1
KLF7

Kruppel-like factor 7 (ubiquitous)

chr12_-_53171128 0.472 ENST00000332411.2
KRT76
keratin 76
chr5_+_150639360 0.472 ENST00000523004.1
GM2A
GM2 ganglioside activator
chr3_-_74570291 0.471 ENST00000263665.6
CNTN3
contactin 3 (plasmacytoma associated)
chr12_-_10022735 0.457 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr8_+_50824233 0.444 ENST00000522124.1
SNTG1
syntrophin, gamma 1
chr16_-_55866997 0.440 ENST00000360526.3
ENST00000361503.4
CES1

carboxylesterase 1

chr4_-_143227088 0.434 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr8_+_22424551 0.427 ENST00000523348.1
SORBS3
sorbin and SH3 domain containing 3
chr3_+_121774202 0.411 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86



CD86 molecule



chr16_-_46655538 0.402 ENST00000303383.3
SHCBP1
SHC SH2-domain binding protein 1
chr11_+_33061543 0.401 ENST00000432887.1
ENST00000528898.1
ENST00000531632.2
TCP11L1


t-complex 11, testis-specific-like 1


chr7_+_77428149 0.398 ENST00000415251.2
ENST00000275575.7
PHTF2

putative homeodomain transcription factor 2

chr12_+_1099675 0.395 ENST00000545318.2
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr16_+_50300427 0.392 ENST00000394697.2
ENST00000566433.2
ENST00000538642.1
ADCY7


adenylate cyclase 7


chr17_+_62223320 0.390 ENST00000580828.1
ENST00000582965.1
SNORA76

small nucleolar RNA, H/ACA box 76

chrX_+_7137475 0.379 ENST00000217961.4
STS
steroid sulfatase (microsomal), isozyme S
chr19_-_59084647 0.377 ENST00000594234.1
ENST00000596039.1
MZF1

myeloid zinc finger 1

chr14_-_95236551 0.375 ENST00000238558.3
GSC
goosecoid homeobox
chr4_-_39979576 0.371 ENST00000303538.8
ENST00000503396.1
PDS5A

PDS5, regulator of cohesion maintenance, homolog A (S. cerevisiae)

chr19_-_7968427 0.364 ENST00000539278.1
AC010336.1
Uncharacterized protein
chr6_+_26199737 0.363 ENST00000359985.1
HIST1H2BF
histone cluster 1, H2bf
chr6_+_34204642 0.363 ENST00000347617.6
ENST00000401473.3
ENST00000311487.5
ENST00000447654.1
ENST00000395004.3
HMGA1




high mobility group AT-hook 1




chr12_-_10955226 0.362 ENST00000240687.2
TAS2R7
taste receptor, type 2, member 7
chr3_-_178984759 0.350 ENST00000349697.2
ENST00000497599.1
KCNMB3

potassium large conductance calcium-activated channel, subfamily M beta member 3

chr3_+_111718173 0.348 ENST00000494932.1
TAGLN3
transgelin 3
chr1_-_78444738 0.343 ENST00000436586.2
ENST00000370768.2
FUBP1

far upstream element (FUSE) binding protein 1

chr1_-_17304771 0.341 ENST00000375534.3
MFAP2
microfibrillar-associated protein 2
chr6_-_32157947 0.338 ENST00000375050.4
PBX2
pre-B-cell leukemia homeobox 2
chr2_-_163008903 0.336 ENST00000418842.2
ENST00000375497.3
GCG

glucagon

chr14_-_55658323 0.328 ENST00000554067.1
ENST00000247191.2
DLGAP5

discs, large (Drosophila) homolog-associated protein 5

chr19_-_51522955 0.327 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr7_-_107642348 0.327 ENST00000393561.1
LAMB1
laminin, beta 1
chr17_-_64225508 0.319 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr19_+_7030589 0.313 ENST00000329753.5
MBD3L5
methyl-CpG binding domain protein 3-like 5
chr10_-_93392811 0.312 ENST00000238994.5
PPP1R3C
protein phosphatase 1, regulatory subunit 3C
chr7_-_100860851 0.312 ENST00000223127.3
PLOD3
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr15_+_94899183 0.309 ENST00000557742.1
MCTP2
multiple C2 domains, transmembrane 2
chr14_-_55658252 0.308 ENST00000395425.2
DLGAP5
discs, large (Drosophila) homolog-associated protein 5
chr19_+_34287751 0.308 ENST00000590771.1
ENST00000589786.1
ENST00000284006.6
ENST00000588881.1
KCTD15



potassium channel tetramerization domain containing 15



chr17_-_57229155 0.306 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr19_-_7040190 0.305 ENST00000381394.4
MBD3L4
methyl-CpG binding domain protein 3-like 4
chrX_+_107288197 0.303 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr19_+_48949030 0.303 ENST00000253237.5
GRWD1
glutamate-rich WD repeat containing 1
chr17_-_38859996 0.298 ENST00000264651.2
KRT24
keratin 24
chr21_+_31768348 0.292 ENST00000355459.2
KRTAP13-1
keratin associated protein 13-1
chr17_-_9694614 0.291 ENST00000330255.5
ENST00000571134.1
DHRS7C

dehydrogenase/reductase (SDR family) member 7C

chr14_+_56584414 0.289 ENST00000559044.1
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr1_-_201140673 0.287 ENST00000367333.2
TMEM9
transmembrane protein 9
chr3_+_111718036 0.275 ENST00000455401.2
TAGLN3
transgelin 3
chr3_+_130569429 0.274 ENST00000505330.1
ENST00000504381.1
ENST00000507488.2
ENST00000393221.4
ATP2C1



ATPase, Ca++ transporting, type 2C, member 1



chr1_-_78444776 0.272 ENST00000370767.1
ENST00000421641.1
FUBP1

far upstream element (FUSE) binding protein 1

chr1_+_62439037 0.268 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr17_+_39394250 0.268 ENST00000254072.6
KRTAP9-8
keratin associated protein 9-8
chr3_+_111717600 0.266 ENST00000273368.4
TAGLN3
transgelin 3
chr20_+_43538692 0.266 ENST00000217074.4
ENST00000255136.3
PABPC1L

poly(A) binding protein, cytoplasmic 1-like

chr12_+_122688090 0.263 ENST00000324189.4
ENST00000546192.1
B3GNT4

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4

chr7_-_25019760 0.263 ENST00000352860.1
ENST00000353930.1
ENST00000431825.2
ENST00000313367.2
OSBPL3



oxysterol binding protein-like 3



chrX_+_107288239 0.262 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr18_+_34124507 0.259 ENST00000591635.1
FHOD3
formin homology 2 domain containing 3
chr20_+_43538756 0.258 ENST00000537323.1
ENST00000217073.2
PABPC1L

poly(A) binding protein, cytoplasmic 1-like

chr11_+_75526212 0.258 ENST00000356136.3
UVRAG
UV radiation resistance associated
chr18_+_59000815 0.255 ENST00000262717.4
CDH20
cadherin 20, type 2
chr6_+_153552455 0.254 ENST00000392385.2
AL590867.1
Uncharacterized protein; cDNA FLJ59044, highly similar to LINE-1 reverse transcriptase homolog
chr19_+_45973120 0.253 ENST00000592811.1
ENST00000586615.1
FOSB

FBJ murine osteosarcoma viral oncogene homolog B

chr3_+_111717511 0.252 ENST00000478951.1
ENST00000393917.2
TAGLN3

transgelin 3

chrX_+_100805496 0.250 ENST00000372829.3
ARMCX1
armadillo repeat containing, X-linked 1
chr8_-_101661887 0.249 ENST00000311812.2
SNX31
sorting nexin 31
chr6_-_111927062 0.248 ENST00000359831.4
TRAF3IP2
TRAF3 interacting protein 2
chr13_-_36050819 0.246 ENST00000379919.4
MAB21L1
mab-21-like 1 (C. elegans)
chr18_-_31803435 0.246 ENST00000589544.1
ENST00000269185.4
ENST00000261592.5
NOL4


nucleolar protein 4


chr18_+_29027696 0.241 ENST00000257189.4
DSG3
desmoglein 3
chr12_-_10007448 0.238 ENST00000538152.1
CLEC2B
C-type lectin domain family 2, member B
chr15_-_55562479 0.237 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr15_-_42264702 0.236 ENST00000220325.4
EHD4
EH-domain containing 4
chr2_-_238322770 0.232 ENST00000472056.1
COL6A3
collagen, type VI, alpha 3
chr1_-_197115818 0.229 ENST00000367409.4
ENST00000294732.7
ASPM

asp (abnormal spindle) homolog, microcephaly associated (Drosophila)

chr2_-_238322800 0.228 ENST00000392004.3
ENST00000433762.1
ENST00000347401.3
ENST00000353578.4
ENST00000346358.4
ENST00000392003.2
COL6A3





collagen, type VI, alpha 3





chr2_-_238323007 0.226 ENST00000295550.4
COL6A3
collagen, type VI, alpha 3
chr3_+_152879985 0.225 ENST00000323534.2
RAP2B
RAP2B, member of RAS oncogene family
chr12_-_57328187 0.222 ENST00000293502.1
SDR9C7
short chain dehydrogenase/reductase family 9C, member 7
chr1_+_10290822 0.220 ENST00000377083.1
KIF1B
kinesin family member 1B
chrX_+_99839799 0.218 ENST00000373031.4
TNMD
tenomodulin
chr8_-_42234745 0.218 ENST00000220812.2
DKK4
dickkopf WNT signaling pathway inhibitor 4
chrX_-_71458802 0.216 ENST00000373657.1
ENST00000334463.3
ERCC6L

excision repair cross-complementing rodent repair deficiency, complementation group 6-like

chr4_+_71200681 0.216 ENST00000273936.5
CABS1
calcium-binding protein, spermatid-specific 1
chr20_-_56286479 0.214 ENST00000265626.4
PMEPA1
prostate transmembrane protein, androgen induced 1
chr1_+_225600404 0.214 ENST00000366845.2
AC092811.1
AC092811.1
chr5_+_115177178 0.214 ENST00000316788.7
AP3S1
adaptor-related protein complex 3, sigma 1 subunit
chr2_-_188419078 0.210 ENST00000437725.1
ENST00000409676.1
ENST00000339091.4
ENST00000420747.1
TFPI



tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor)



chr6_+_151186554 0.210 ENST00000367321.3
ENST00000367307.4
MTHFD1L

methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like

chr12_+_53662073 0.210 ENST00000553219.1
ENST00000257934.4
ESPL1

extra spindle pole bodies homolog 1 (S. cerevisiae)

chr10_-_49813090 0.209 ENST00000249601.4
ARHGAP22
Rho GTPase activating protein 22
chr1_+_153746683 0.207 ENST00000271857.2
SLC27A3
solute carrier family 27 (fatty acid transporter), member 3
chr1_+_206138457 0.204 ENST00000367128.3
ENST00000431655.2
FAM72A

family with sequence similarity 72, member A

chr1_-_143913143 0.203 ENST00000400889.1
FAM72D
family with sequence similarity 72, member D
chr11_-_62313090 0.202 ENST00000528508.1
ENST00000533365.1
AHNAK

AHNAK nucleoprotein

chr9_-_131486367 0.200 ENST00000372663.4
ENST00000406904.2
ENST00000452105.1
ENST00000372672.2
ENST00000372667.5
ZDHHC12




zinc finger, DHHC-type containing 12




chr10_+_6779326 0.199 ENST00000417112.1
RP11-554I8.2
RP11-554I8.2
chr11_-_124190184 0.198 ENST00000357438.2
OR8D2
olfactory receptor, family 8, subfamily D, member 2
chr1_+_120839005 0.198 ENST00000369390.3
ENST00000452190.1
FAM72B

family with sequence similarity 72, member B

chr8_+_98881268 0.197 ENST00000254898.5
ENST00000524308.1
ENST00000522025.2
MATN2


matrilin 2


chr6_+_43968306 0.197 ENST00000442114.2
ENST00000336600.5
ENST00000439969.2
C6orf223


chromosome 6 open reading frame 223


chr1_-_67266939 0.197 ENST00000304526.2
INSL5
insulin-like 5
chr13_-_30881134 0.197 ENST00000380617.3
ENST00000441394.1
KATNAL1

katanin p60 subunit A-like 1

chr19_+_41869894 0.196 ENST00000413014.2
TMEM91
transmembrane protein 91
chr10_-_48416849 0.194 ENST00000249598.1
GDF2
growth differentiation factor 2
chr3_-_151034734 0.192 ENST00000260843.4
GPR87
G protein-coupled receptor 87
chr8_+_42873548 0.190 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr22_-_32766972 0.189 ENST00000382084.4
ENST00000382086.2
RFPL3S

RFPL3 antisense

chr10_-_33623310 0.187 ENST00000395995.1
ENST00000374823.5
ENST00000374821.5
ENST00000374816.3
NRP1



neuropilin 1



chr6_-_32145861 0.187 ENST00000336984.6
AGPAT1
1-acylglycerol-3-phosphate O-acyltransferase 1
chr12_-_14849470 0.177 ENST00000261170.3
GUCY2C
guanylate cyclase 2C (heat stable enterotoxin receptor)
chr15_+_63188009 0.176 ENST00000557900.1
RP11-1069G10.2
RP11-1069G10.2
chr14_+_29236269 0.176 ENST00000313071.4
FOXG1
forkhead box G1
chr14_+_68086515 0.176 ENST00000261783.3
ARG2
arginase 2
chr9_+_12693336 0.175 ENST00000381137.2
ENST00000388918.5
TYRP1

tyrosinase-related protein 1

chr15_-_55563072 0.174 ENST00000567380.1
ENST00000565972.1
ENST00000569493.1
RAB27A


RAB27A, member RAS oncogene family


chr8_+_98900132 0.174 ENST00000520016.1
MATN2
matrilin 2
chr11_-_71823266 0.174 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15


anaphase promoting complex subunit 15


chr4_-_143226979 0.173 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr12_+_53662110 0.172 ENST00000552462.1
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr3_-_141747950 0.171 ENST00000497579.1
TFDP2
transcription factor Dp-2 (E2F dimerization partner 2)
chr19_+_3762703 0.171 ENST00000589174.1
MRPL54
mitochondrial ribosomal protein L54
chr9_+_125133315 0.171 ENST00000223423.4
ENST00000362012.2
PTGS1

prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase)

chr12_+_52056548 0.170 ENST00000545061.1
ENST00000355133.3
SCN8A

sodium channel, voltage gated, type VIII, alpha subunit

chr17_-_39341594 0.169 ENST00000398472.1
KRTAP4-1
keratin associated protein 4-1
chr15_+_58430567 0.167 ENST00000536493.1
AQP9
aquaporin 9
chr12_+_28410128 0.166 ENST00000381259.1
ENST00000381256.1
CCDC91

coiled-coil domain containing 91

chr2_+_90248739 0.164 ENST00000468879.1
IGKV1D-43
immunoglobulin kappa variable 1D-43
chrX_+_135730297 0.161 ENST00000370629.2
CD40LG
CD40 ligand
chr3_+_185431080 0.161 ENST00000296270.1
C3orf65
chromosome 3 open reading frame 65
chr14_-_106494587 0.160 ENST00000390597.2
IGHV2-5
immunoglobulin heavy variable 2-5
chr13_-_86373536 0.160 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chr16_+_12059050 0.159 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chrX_-_100129128 0.157 ENST00000372960.4
ENST00000372964.1
ENST00000217885.5
NOX1


NADPH oxidase 1


chr16_-_20702578 0.156 ENST00000307493.4
ENST00000219151.4
ACSM1

acyl-CoA synthetase medium-chain family member 1

chr6_-_111927449 0.156 ENST00000368761.5
ENST00000392556.4
ENST00000340026.6
TRAF3IP2


TRAF3 interacting protein 2


chr3_-_33686925 0.156 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2


cytoplasmic linker associated protein 2


chr2_+_89184868 0.156 ENST00000390243.2
IGKV4-1
immunoglobulin kappa variable 4-1
chr15_+_89164520 0.152 ENST00000332810.3
AEN
apoptosis enhancing nuclease
chr4_+_70796784 0.149 ENST00000246891.4
ENST00000444405.3
CSN1S1

casein alpha s1

chr4_-_8873531 0.148 ENST00000400677.3
HMX1
H6 family homeobox 1
chrX_-_77225135 0.148 ENST00000458128.1
PGAM4
phosphoglycerate mutase family member 4
chr2_+_143635067 0.147 ENST00000264170.4
KYNU
kynureninase
chr7_+_100136811 0.147 ENST00000300176.4
ENST00000262935.4
AGFG2

ArfGAP with FG repeats 2

chr3_+_156799587 0.147 ENST00000469196.1
RP11-6F2.5
RP11-6F2.5
chr17_-_46716647 0.146 ENST00000608940.1
RP11-357H14.17
RP11-357H14.17
chr1_+_152974218 0.145 ENST00000331860.3
ENST00000443178.1
ENST00000295367.4
SPRR3


small proline-rich protein 3


chr10_+_5005598 0.145 ENST00000442997.1
AKR1C1
aldo-keto reductase family 1, member C1
chr22_-_32767017 0.144 ENST00000400234.1
RFPL3S
RFPL3 antisense
chr4_-_103749179 0.143 ENST00000502690.1
UBE2D3
ubiquitin-conjugating enzyme E2D 3
chr7_-_92777606 0.143 ENST00000437805.1
ENST00000446959.1
ENST00000439952.1
ENST00000414791.1
ENST00000446033.1
ENST00000411955.1
ENST00000318238.4
SAMD9L






sterile alpha motif domain containing 9-like






chrX_+_49687267 0.142 ENST00000376091.3
CLCN5
chloride channel, voltage-sensitive 5
chr9_-_107690420 0.142 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1


ATP-binding cassette, sub-family A (ABC1), member 1


chr16_+_69345243 0.141 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)
chr10_-_101825151 0.141 ENST00000441382.1
CPN1
carboxypeptidase N, polypeptide 1
chr8_-_42623747 0.141 ENST00000534622.1
CHRNA6
cholinergic receptor, nicotinic, alpha 6 (neuronal)
chr10_+_81272287 0.140 ENST00000520547.2
EIF5AL1
eukaryotic translation initiation factor 5A-like 1
chr9_+_116225999 0.139 ENST00000317613.6
RGS3
regulator of G-protein signaling 3
chr2_+_68961934 0.139 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr4_-_116034979 0.136 ENST00000264363.2
NDST4
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 4
chr5_-_9630463 0.136 ENST00000382492.2
TAS2R1
taste receptor, type 2, member 1
chr1_+_84609944 0.136 ENST00000370685.3
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr5_+_179159813 0.136 ENST00000292599.3
MAML1
mastermind-like 1 (Drosophila)
chr18_-_3219847 0.136 ENST00000261606.7
MYOM1
myomesin 1
chr2_+_68961905 0.136 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr1_-_151762943 0.135 ENST00000368825.3
ENST00000368823.1
ENST00000458431.2
ENST00000368827.6
ENST00000368824.3
TDRKH




tudor and KH domain containing




chr12_-_56694142 0.133 ENST00000550655.1
ENST00000548567.1
ENST00000551430.2
ENST00000351328.3
CS



citrate synthase



chr14_+_22748980 0.132 ENST00000390465.2
TRAV38-2DV8
T cell receptor alpha variable 38-2/delta variable 8
chr16_+_57279004 0.131 ENST00000219204.3
ARL2BP
ADP-ribosylation factor-like 2 binding protein
chr5_+_140529630 0.131 ENST00000543635.1
PCDHB6
protocadherin beta 6
chr19_+_39421556 0.130 ENST00000407800.2
ENST00000402029.3
MRPS12

mitochondrial ribosomal protein S12

chr12_+_72058130 0.130 ENST00000547843.1
THAP2
THAP domain containing, apoptosis associated protein 2
chrX_-_18690210 0.129 ENST00000379984.3
RS1
retinoschisin 1
chr14_+_74815116 0.127 ENST00000256362.4
VRTN
vertebrae development associated
chr6_-_29395509 0.126 ENST00000377147.2
OR11A1
olfactory receptor, family 11, subfamily A, member 1

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.2 0.2 GO:0035990 tendon cell differentiation(GO:0035990) tendon formation(GO:0035992)
0.1 0.4 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.4 GO:0014034 neural crest cell fate commitment(GO:0014034)
0.1 1.3 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.1 0.4 GO:0090119 vesicle-mediated cholesterol transport(GO:0090119)
0.1 0.6 GO:0007079 mitotic chromosome movement towards spindle pole(GO:0007079)
0.1 0.6 GO:0016479 negative regulation of transcription from RNA polymerase I promoter(GO:0016479)
0.1 0.3 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.3 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.3 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.4 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.4 GO:0090402 oncogene-induced cell senescence(GO:0090402)
0.1 0.2 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395) negative regulation of neuromuscular junction development(GO:1904397)
0.1 0.8 GO:0007144 female meiosis I(GO:0007144)
0.1 0.3 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.1 0.3 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.4 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.1 0.2 GO:1904647 response to rotenone(GO:1904647)
0.1 0.7 GO:0050776 regulation of immune response(GO:0050776)
0.1 0.2 GO:0009257 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.1 0.2 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 0.5 GO:0006689 ganglioside catabolic process(GO:0006689)
0.0 0.2 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.3 GO:0048050 post-embryonic eye morphogenesis(GO:0048050)
0.0 0.3 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.5 GO:0048733 sebaceous gland development(GO:0048733)
0.0 1.6 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.6 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0003162 atrioventricular node development(GO:0003162)
0.0 0.3 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 1.2 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.2 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.1 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.0 0.1 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.0 0.2 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.1 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.4 GO:0051918 negative regulation of fibrinolysis(GO:0051918)
0.0 0.1 GO:0015917 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 1.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:1903625 negative regulation of DNA catabolic process(GO:1903625)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.0 0.1 GO:0090271 positive regulation of fibroblast growth factor production(GO:0090271)
0.0 0.2 GO:0051799 negative regulation of hair follicle development(GO:0051799)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.6 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.1 GO:0014057 positive regulation of acetylcholine secretion, neurotransmission(GO:0014057)
0.0 0.2 GO:0021562 vestibulocochlear nerve development(GO:0021562)
0.0 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.7 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0007598 blood coagulation, extrinsic pathway(GO:0007598)
0.0 0.2 GO:0009753 response to jasmonic acid(GO:0009753) cellular response to jasmonic acid stimulus(GO:0071395)
0.0 0.6 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.1 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.0 0.2 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.2 GO:0051013 microtubule severing(GO:0051013)
0.0 0.3 GO:0000050 urea cycle(GO:0000050)
0.0 0.2 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.0 0.0 GO:0070666 regulation of mast cell proliferation(GO:0070666) positive regulation of mast cell proliferation(GO:0070668)
0.0 0.1 GO:0042816 vitamin B6 metabolic process(GO:0042816)
0.0 0.4 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 0.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.1 GO:0003335 corneocyte development(GO:0003335)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.2 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.1 GO:0048241 epinephrine transport(GO:0048241)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0044249 cellular biosynthetic process(GO:0044249)
0.0 0.2 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.6 GO:0048305 immunoglobulin secretion(GO:0048305)
0.0 0.1 GO:1990523 response to vitamin K(GO:0032571) bone regeneration(GO:1990523)
0.0 0.2 GO:0060394 negative regulation of SMAD protein complex assembly(GO:0010991) negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.3 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.0 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.3 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.0 0.2 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.0 GO:0009946 proximal/distal axis specification(GO:0009946)
0.0 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.1 GO:0015811 L-alanine transport(GO:0015808) L-cystine transport(GO:0015811)
0.0 0.0 GO:1903989 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641)
0.0 0.0 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.0 0.1 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.0 GO:1901228 positive regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003257) negative regulation of beta-amyloid clearance(GO:1900222) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.0 0.3 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0002934 desmosome organization(GO:0002934)
0.0 0.4 GO:0006706 steroid catabolic process(GO:0006706)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.1 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.1 GO:1901529 positive regulation of anion channel activity(GO:1901529)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.2 GO:1903779 regulation of cardiac conduction(GO:1903779)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.0 GO:0006550 isoleucine catabolic process(GO:0006550)
0.0 0.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.1 GO:0030202 heparin metabolic process(GO:0030202) heparin biosynthetic process(GO:0030210)
0.0 0.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.3 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.2 GO:0046459 short-chain fatty acid metabolic process(GO:0046459)
0.0 0.1 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.0 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.1 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0031523 Myb complex(GO:0031523)
0.1 0.5 GO:0005889 hydrogen:potassium-exchanging ATPase complex(GO:0005889)
0.1 0.3 GO:0005607 laminin-2 complex(GO:0005607)
0.1 0.5 GO:0016013 syntrophin complex(GO:0016013)
0.1 0.7 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.0 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.0 0.2 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.6 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.6 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0033565 ESCRT-0 complex(GO:0033565)
0.0 0.4 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.1 GO:0036338 viral envelope(GO:0019031) viral membrane(GO:0036338)
0.0 0.1 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0071547 piP-body(GO:0071547)
0.0 0.3 GO:0030897 HOPS complex(GO:0030897)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:1990075 periciliary membrane compartment(GO:1990075)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.1 GO:0030686 90S preribosome(GO:0030686)
0.0 0.0 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.0 GO:0033186 CAF-1 complex(GO:0033186)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 0.3 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0042584 chromaffin granule membrane(GO:0042584)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.6 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.3 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 0.6 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 0.4 GO:0047374 methylumbelliferyl-acetate deacetylase activity(GO:0047374)
0.1 1.3 GO:0048185 activin binding(GO:0048185)
0.1 0.3 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.1 1.4 GO:0033038 bitter taste receptor activity(GO:0033038)
0.1 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 1.8 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.1 0.2 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.2 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0004666 prostaglandin-endoperoxide synthase activity(GO:0004666)
0.0 0.1 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.3 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.1 GO:0046538 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.1 GO:0047718 17-alpha,20-alpha-dihydroxypregn-4-en-3-one dehydrogenase activity(GO:0047006) androsterone dehydrogenase activity(GO:0047023) indanol dehydrogenase activity(GO:0047718)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.1 GO:0004803 transposase activity(GO:0004803)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0008513 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.2 GO:0030021 extracellular matrix structural constituent conferring compression resistance(GO:0030021) structural constituent of tooth enamel(GO:0030345)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.1 GO:0047273 galactosylgalactosylglucosylceramide beta-D-acetylgalactosaminyltransferase activity(GO:0047273)
0.0 0.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.4 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.1 GO:0005148 prolactin receptor binding(GO:0005148)
0.0 0.5 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.6 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 1.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.3 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.0 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.6 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.0 GO:0000994 RNA polymerase III core binding(GO:0000994)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.1 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-cystine transmembrane transporter activity(GO:0015184) alanine transmembrane transporter activity(GO:0022858)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0043398 HLH domain binding(GO:0043398)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 1.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0005502 11-cis retinal binding(GO:0005502)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.0 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.1 GO:0010465 nerve growth factor receptor activity(GO:0010465)
0.0 0.0 GO:0018636 phenanthrene 9,10-monooxygenase activity(GO:0018636) ketosteroid monooxygenase activity(GO:0047086)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.2 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.2 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.4 SA_PROGRAMMED_CELL_DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.7 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 1.2 PID_BMP_PATHWAY BMP receptor signaling
0.0 1.0 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.8 PID_AURORA_A_PATHWAY Aurora A signaling
0.0 0.4 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 0.7 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.2 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME_ERKS_ARE_INACTIVATED Genes involved in ERKs are inactivated
0.0 0.4 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.6 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.8 REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.0 0.4 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.4 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 1.9 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)
0.0 0.3 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.3 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.4 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.4 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.2 REACTOME_ABACAVIR_TRANSPORT_AND_METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.2 REACTOME_IRAK2_MEDIATED_ACTIVATION_OF_TAK1_COMPLEX_UPON_TLR7_8_OR_9_STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.2 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 1.7 REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.5 REACTOME_STEROID_HORMONES Genes involved in Steroid hormones
0.0 0.2 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.9 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.5 REACTOME_GLYCOSPHINGOLIPID_METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME_CGMP_EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME_SPRY_REGULATION_OF_FGF_SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.2 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism