Motif ID: EP300
Z-value: 1.279
Transcription factors associated with EP300:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| EP300 | ENSG00000100393.9 | EP300 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| EP300 | hg19_v2_chr22_+_41487711_41487798 | -0.28 | 1.8e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 5.1 | GO:0019858 | cytosine metabolic process(GO:0019858) |
| 1.5 | 7.5 | GO:0060356 | leucine import(GO:0060356) |
| 0.9 | 2.6 | GO:0035623 | regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623) |
| 0.8 | 3.2 | GO:0006218 | uridine catabolic process(GO:0006218) |
| 0.8 | 6.2 | GO:0060744 | thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) |
| 0.7 | 2.2 | GO:1903926 | signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926) |
| 0.7 | 2.1 | GO:0000412 | histone peptidyl-prolyl isomerization(GO:0000412) |
| 0.6 | 1.8 | GO:0002276 | basophil activation involved in immune response(GO:0002276) |
| 0.6 | 3.3 | GO:0016479 | negative regulation of transcription from RNA polymerase I promoter(GO:0016479) |
| 0.5 | 1.6 | GO:0014724 | regulation of twitch skeletal muscle contraction(GO:0014724) fast-twitch skeletal muscle fiber contraction(GO:0031443) relaxation of skeletal muscle(GO:0090076) |
| 0.5 | 1.9 | GO:0035026 | leading edge cell differentiation(GO:0035026) |
| 0.5 | 2.4 | GO:0002669 | positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519) |
| 0.4 | 3.7 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
| 0.4 | 0.4 | GO:0051885 | positive regulation of anagen(GO:0051885) |
| 0.4 | 1.6 | GO:0033123 | positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123) |
| 0.4 | 1.6 | GO:0010752 | regulation of cGMP-mediated signaling(GO:0010752) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) |
| 0.4 | 3.1 | GO:0014721 | voluntary skeletal muscle contraction(GO:0003010) twitch skeletal muscle contraction(GO:0014721) slow-twitch skeletal muscle fiber contraction(GO:0031444) |
| 0.4 | 1.1 | GO:1903570 | regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572) |
| 0.4 | 3.3 | GO:0086073 | bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073) |
| 0.4 | 2.2 | GO:0007079 | mitotic chromosome movement towards spindle pole(GO:0007079) |
| 0.4 | 1.8 | GO:0033274 | response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829) |
| 0.3 | 1.0 | GO:1901876 | regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) |
| 0.3 | 1.0 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
| 0.3 | 2.0 | GO:0030421 | defecation(GO:0030421) |
| 0.3 | 1.0 | GO:0060762 | regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) |
| 0.3 | 2.6 | GO:0060753 | regulation of mast cell chemotaxis(GO:0060753) |
| 0.3 | 0.9 | GO:0072579 | molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579) |
| 0.3 | 4.8 | GO:0051639 | actin filament network formation(GO:0051639) |
| 0.3 | 0.9 | GO:0006500 | N-terminal protein palmitoylation(GO:0006500) |
| 0.3 | 1.5 | GO:0071460 | cellular response to cell-matrix adhesion(GO:0071460) |
| 0.3 | 0.8 | GO:0006550 | isoleucine catabolic process(GO:0006550) |
| 0.3 | 0.8 | GO:0019085 | early viral transcription(GO:0019085) |
| 0.3 | 0.8 | GO:0097252 | renal albumin absorption(GO:0097018) oligodendrocyte apoptotic process(GO:0097252) regulation of renal albumin absorption(GO:2000532) |
| 0.3 | 0.8 | GO:1903989 | regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440) response to iron ion starvation(GO:1990641) |
| 0.2 | 1.0 | GO:1903490 | regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490) |
| 0.2 | 0.9 | GO:0014054 | positive regulation of gamma-aminobutyric acid secretion(GO:0014054) |
| 0.2 | 0.7 | GO:0002541 | activation of plasma proteins involved in acute inflammatory response(GO:0002541) |
| 0.2 | 0.9 | GO:0003409 | optic cup structural organization(GO:0003409) |
| 0.2 | 0.9 | GO:0036228 | protein targeting to nuclear inner membrane(GO:0036228) |
| 0.2 | 2.4 | GO:1900029 | positive regulation of ruffle assembly(GO:1900029) |
| 0.2 | 1.0 | GO:1903336 | negative regulation of vacuolar transport(GO:1903336) |
| 0.2 | 2.0 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
| 0.2 | 0.8 | GO:0046122 | purine deoxyribonucleoside metabolic process(GO:0046122) |
| 0.2 | 2.2 | GO:0032287 | peripheral nervous system myelin maintenance(GO:0032287) |
| 0.2 | 0.6 | GO:0045014 | carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014) |
| 0.2 | 2.3 | GO:0061087 | positive regulation of histone H3-K27 methylation(GO:0061087) |
| 0.2 | 2.0 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
| 0.2 | 1.1 | GO:0008063 | Toll signaling pathway(GO:0008063) |
| 0.2 | 0.6 | GO:0002522 | leukocyte migration involved in immune response(GO:0002522) |
| 0.2 | 1.1 | GO:0010756 | positive regulation of plasminogen activation(GO:0010756) |
| 0.2 | 0.9 | GO:0002378 | immunoglobulin biosynthetic process(GO:0002378) |
| 0.2 | 1.5 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
| 0.2 | 0.9 | GO:0021553 | olfactory nerve development(GO:0021553) |
| 0.2 | 0.7 | GO:0046952 | ketone body catabolic process(GO:0046952) |
| 0.2 | 1.2 | GO:1904431 | positive regulation of t-circle formation(GO:1904431) |
| 0.2 | 1.3 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
| 0.2 | 0.8 | GO:0019470 | 4-hydroxyproline catabolic process(GO:0019470) |
| 0.2 | 0.9 | GO:2000543 | positive regulation of gastrulation(GO:2000543) |
| 0.2 | 1.1 | GO:1902714 | negative regulation of interferon-gamma secretion(GO:1902714) |
| 0.2 | 0.9 | GO:0010836 | negative regulation of protein ADP-ribosylation(GO:0010836) |
| 0.2 | 1.1 | GO:0090649 | response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650) |
| 0.2 | 0.6 | GO:2000286 | receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.1 | 0.9 | GO:0060979 | vasculogenesis involved in coronary vascular morphogenesis(GO:0060979) |
| 0.1 | 1.6 | GO:1901725 | regulation of histone deacetylase activity(GO:1901725) |
| 0.1 | 0.9 | GO:0071105 | response to interleukin-11(GO:0071105) |
| 0.1 | 0.4 | GO:0017186 | peptidyl-pyroglutamic acid biosynthetic process, using glutaminyl-peptide cyclotransferase(GO:0017186) |
| 0.1 | 0.9 | GO:0097338 | response to clozapine(GO:0097338) |
| 0.1 | 1.3 | GO:2000535 | regulation of entry of bacterium into host cell(GO:2000535) |
| 0.1 | 4.1 | GO:0006491 | N-glycan processing(GO:0006491) |
| 0.1 | 0.7 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
| 0.1 | 0.5 | GO:0009298 | GDP-mannose biosynthetic process(GO:0009298) |
| 0.1 | 0.5 | GO:0014022 | neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007) |
| 0.1 | 0.2 | GO:0046601 | positive regulation of centriole replication(GO:0046601) |
| 0.1 | 0.5 | GO:0045578 | negative regulation of B cell differentiation(GO:0045578) negative regulation of follicle-stimulating hormone secretion(GO:0046882) |
| 0.1 | 1.5 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.1 | 1.6 | GO:0035092 | sperm chromatin condensation(GO:0035092) |
| 0.1 | 0.3 | GO:0048133 | germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728) |
| 0.1 | 0.5 | GO:0006049 | UDP-N-acetylglucosamine catabolic process(GO:0006049) |
| 0.1 | 0.5 | GO:0060391 | positive regulation of SMAD protein import into nucleus(GO:0060391) |
| 0.1 | 0.2 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
| 0.1 | 0.3 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
| 0.1 | 0.5 | GO:0045198 | establishment of epithelial cell apical/basal polarity(GO:0045198) |
| 0.1 | 0.8 | GO:0030578 | PML body organization(GO:0030578) |
| 0.1 | 0.3 | GO:0050902 | leukocyte adhesive activation(GO:0050902) |
| 0.1 | 1.7 | GO:0043248 | proteasome assembly(GO:0043248) |
| 0.1 | 0.2 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
| 0.1 | 0.3 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.1 | 0.3 | GO:0010725 | regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854) |
| 0.1 | 0.4 | GO:0090309 | positive regulation of methylation-dependent chromatin silencing(GO:0090309) |
| 0.1 | 1.5 | GO:0035641 | locomotory exploration behavior(GO:0035641) |
| 0.1 | 1.2 | GO:2000675 | negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
| 0.1 | 0.7 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
| 0.1 | 0.3 | GO:0007538 | primary sex determination(GO:0007538) |
| 0.1 | 0.2 | GO:0002143 | tRNA wobble position uridine thiolation(GO:0002143) |
| 0.1 | 1.3 | GO:0045793 | positive regulation of cell size(GO:0045793) |
| 0.1 | 0.4 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
| 0.1 | 0.5 | GO:1905150 | regulation of voltage-gated sodium channel activity(GO:1905150) |
| 0.1 | 0.4 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.1 | 0.8 | GO:0002315 | marginal zone B cell differentiation(GO:0002315) |
| 0.1 | 0.9 | GO:0000733 | DNA strand renaturation(GO:0000733) |
| 0.1 | 0.7 | GO:0051001 | negative regulation of nitric-oxide synthase activity(GO:0051001) |
| 0.1 | 2.0 | GO:0030033 | microvillus assembly(GO:0030033) |
| 0.1 | 0.6 | GO:0019368 | fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626) |
| 0.1 | 0.3 | GO:0043376 | regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) |
| 0.1 | 0.3 | GO:0015917 | aminophospholipid transport(GO:0015917) |
| 0.1 | 0.5 | GO:0060154 | cellular process regulating host cell cycle in response to virus(GO:0060154) |
| 0.1 | 1.1 | GO:0045722 | positive regulation of gluconeogenesis(GO:0045722) |
| 0.1 | 0.9 | GO:0015693 | magnesium ion transport(GO:0015693) |
| 0.1 | 1.6 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
| 0.1 | 0.4 | GO:0070779 | D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779) |
| 0.1 | 0.9 | GO:0044351 | macropinocytosis(GO:0044351) |
| 0.1 | 0.2 | GO:0071680 | response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681) |
| 0.1 | 0.6 | GO:0031119 | tRNA pseudouridine synthesis(GO:0031119) |
| 0.1 | 0.2 | GO:0085020 | protein K6-linked ubiquitination(GO:0085020) |
| 0.1 | 0.5 | GO:0051673 | membrane disruption in other organism(GO:0051673) |
| 0.1 | 1.2 | GO:0048742 | regulation of skeletal muscle fiber development(GO:0048742) |
| 0.1 | 2.4 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.1 | 0.8 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
| 0.1 | 0.2 | GO:0070172 | positive regulation of tooth mineralization(GO:0070172) |
| 0.1 | 0.3 | GO:0035469 | determination of pancreatic left/right asymmetry(GO:0035469) |
| 0.1 | 1.2 | GO:1900027 | regulation of ruffle assembly(GO:1900027) |
| 0.1 | 0.5 | GO:0051418 | interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418) |
| 0.1 | 1.6 | GO:0006833 | water transport(GO:0006833) |
| 0.1 | 0.9 | GO:0010457 | centriole-centriole cohesion(GO:0010457) |
| 0.0 | 0.4 | GO:0019317 | fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355) |
| 0.0 | 0.1 | GO:0043314 | negative regulation of neutrophil degranulation(GO:0043314) |
| 0.0 | 0.0 | GO:0099545 | trans-synaptic signaling by trans-synaptic complex(GO:0099545) |
| 0.0 | 0.1 | GO:1900110 | negative regulation of histone H3-K9 dimethylation(GO:1900110) regulation of TORC2 signaling(GO:1903939) |
| 0.0 | 3.4 | GO:0021762 | substantia nigra development(GO:0021762) |
| 0.0 | 0.6 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.0 | 0.2 | GO:0014718 | positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) |
| 0.0 | 2.6 | GO:0043268 | positive regulation of potassium ion transport(GO:0043268) |
| 0.0 | 0.2 | GO:0001827 | inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828) |
| 0.0 | 0.4 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
| 0.0 | 1.4 | GO:0006294 | nucleotide-excision repair, preincision complex assembly(GO:0006294) |
| 0.0 | 1.8 | GO:0007417 | central nervous system development(GO:0007417) |
| 0.0 | 0.9 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.0 | 0.3 | GO:0060484 | lung-associated mesenchyme development(GO:0060484) |
| 0.0 | 0.8 | GO:0090023 | positive regulation of neutrophil chemotaxis(GO:0090023) |
| 0.0 | 0.4 | GO:0048251 | elastic fiber assembly(GO:0048251) |
| 0.0 | 0.3 | GO:2001256 | regulation of store-operated calcium entry(GO:2001256) |
| 0.0 | 0.2 | GO:0035897 | proteolysis in other organism(GO:0035897) |
| 0.0 | 0.2 | GO:1901097 | negative regulation of autophagosome maturation(GO:1901097) |
| 0.0 | 0.1 | GO:0046338 | phosphatidylethanolamine catabolic process(GO:0046338) |
| 0.0 | 2.0 | GO:0008088 | axo-dendritic transport(GO:0008088) |
| 0.0 | 0.1 | GO:0048701 | embryonic cranial skeleton morphogenesis(GO:0048701) cranial skeletal system development(GO:1904888) |
| 0.0 | 0.2 | GO:0017185 | peptidyl-lysine hydroxylation(GO:0017185) |
| 0.0 | 0.4 | GO:0031953 | negative regulation of protein autophosphorylation(GO:0031953) glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860) |
| 0.0 | 0.1 | GO:0021526 | medial motor column neuron differentiation(GO:0021526) |
| 0.0 | 2.4 | GO:0030049 | muscle filament sliding(GO:0030049) actin-myosin filament sliding(GO:0033275) |
| 0.0 | 0.4 | GO:1900227 | positive regulation of NLRP3 inflammasome complex assembly(GO:1900227) |
| 0.0 | 0.7 | GO:0045332 | phospholipid translocation(GO:0045332) |
| 0.0 | 0.9 | GO:0006884 | cell volume homeostasis(GO:0006884) |
| 0.0 | 0.4 | GO:0060137 | maternal process involved in parturition(GO:0060137) |
| 0.0 | 0.9 | GO:0045104 | intermediate filament cytoskeleton organization(GO:0045104) |
| 0.0 | 0.5 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.0 | 0.6 | GO:2000369 | regulation of clathrin-mediated endocytosis(GO:2000369) |
| 0.0 | 0.5 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.0 | 0.9 | GO:0006359 | regulation of transcription from RNA polymerase III promoter(GO:0006359) |
| 0.0 | 0.3 | GO:1902969 | mitotic DNA replication(GO:1902969) |
| 0.0 | 0.5 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.0 | 0.6 | GO:0098779 | mitophagy in response to mitochondrial depolarization(GO:0098779) |
| 0.0 | 0.3 | GO:0006183 | GTP biosynthetic process(GO:0006183) |
| 0.0 | 0.3 | GO:0015747 | urate transport(GO:0015747) |
| 0.0 | 0.3 | GO:0007567 | parturition(GO:0007567) |
| 0.0 | 0.2 | GO:0035385 | Roundabout signaling pathway(GO:0035385) |
| 0.0 | 0.9 | GO:0006693 | prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693) |
| 0.0 | 0.1 | GO:1902809 | regulation of skeletal muscle fiber differentiation(GO:1902809) |
| 0.0 | 0.1 | GO:0038188 | cholecystokinin signaling pathway(GO:0038188) |
| 0.0 | 0.4 | GO:0015866 | ADP transport(GO:0015866) |
| 0.0 | 0.7 | GO:0060216 | definitive hemopoiesis(GO:0060216) |
| 0.0 | 0.1 | GO:0002296 | T-helper 1 cell lineage commitment(GO:0002296) |
| 0.0 | 0.2 | GO:0071313 | cellular response to caffeine(GO:0071313) |
| 0.0 | 0.1 | GO:0006004 | fucose metabolic process(GO:0006004) |
| 0.0 | 0.8 | GO:0000266 | mitochondrial fission(GO:0000266) |
| 0.0 | 0.1 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
| 0.0 | 0.6 | GO:0031032 | actomyosin structure organization(GO:0031032) |
| 0.0 | 1.8 | GO:0006027 | glycosaminoglycan catabolic process(GO:0006027) |
| 0.0 | 0.1 | GO:0090050 | positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050) |
| 0.0 | 0.3 | GO:0034975 | protein folding in endoplasmic reticulum(GO:0034975) |
| 0.0 | 0.2 | GO:0035235 | ionotropic glutamate receptor signaling pathway(GO:0035235) |
| 0.0 | 0.2 | GO:0042373 | vitamin K metabolic process(GO:0042373) |
| 0.0 | 0.6 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
| 0.0 | 0.4 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.0 | 0.6 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.0 | 0.6 | GO:0030097 | hemopoiesis(GO:0030097) |
| 0.0 | 0.5 | GO:0034080 | CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641) |
| 0.0 | 0.7 | GO:0034383 | low-density lipoprotein particle clearance(GO:0034383) |
| 0.0 | 0.1 | GO:0010936 | negative regulation of macrophage cytokine production(GO:0010936) |
| 0.0 | 0.2 | GO:0006878 | cellular copper ion homeostasis(GO:0006878) |
| 0.0 | 0.4 | GO:0007202 | activation of phospholipase C activity(GO:0007202) |
| 0.0 | 0.2 | GO:2000480 | negative regulation of cAMP-dependent protein kinase activity(GO:2000480) |
| 0.0 | 0.4 | GO:0048026 | positive regulation of mRNA splicing, via spliceosome(GO:0048026) |
| 0.0 | 0.2 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
| 0.0 | 1.0 | GO:0046847 | filopodium assembly(GO:0046847) |
| 0.0 | 0.3 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.5 | GO:0009607 | response to biotic stimulus(GO:0009607) |
| 0.0 | 0.5 | GO:0042255 | ribosome assembly(GO:0042255) |
| 0.0 | 0.6 | GO:0051966 | regulation of synaptic transmission, glutamatergic(GO:0051966) |
| 0.0 | 0.7 | GO:0048675 | axon extension(GO:0048675) |
| 0.0 | 0.1 | GO:2000490 | negative regulation of hepatic stellate cell activation(GO:2000490) |
| 0.0 | 0.4 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
| 0.0 | 0.1 | GO:0006701 | progesterone biosynthetic process(GO:0006701) Sertoli cell proliferation(GO:0060011) |
| 0.0 | 0.2 | GO:0001696 | gastric acid secretion(GO:0001696) |
| 0.0 | 1.2 | GO:0030048 | actin filament-based movement(GO:0030048) |
| 0.0 | 0.1 | GO:0035331 | negative regulation of hippo signaling(GO:0035331) |
| 0.0 | 0.5 | GO:0008038 | neuron recognition(GO:0008038) |
| 0.0 | 0.4 | GO:0005980 | glycogen catabolic process(GO:0005980) |
| 0.0 | 0.4 | GO:0050982 | detection of mechanical stimulus(GO:0050982) |
| 0.0 | 0.4 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
| 0.0 | 0.2 | GO:0007507 | heart development(GO:0007507) |
| 0.0 | 0.3 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 3.3 | GO:0031523 | Myb complex(GO:0031523) |
| 0.4 | 1.4 | GO:0070985 | TFIIK complex(GO:0070985) |
| 0.4 | 1.8 | GO:0035838 | growing cell tip(GO:0035838) |
| 0.3 | 4.8 | GO:0005916 | fascia adherens(GO:0005916) |
| 0.3 | 0.9 | GO:0010370 | perinucleolar chromocenter(GO:0010370) |
| 0.2 | 2.9 | GO:0097433 | dense body(GO:0097433) |
| 0.2 | 0.9 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.2 | 1.9 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
| 0.2 | 1.7 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
| 0.2 | 0.5 | GO:0043511 | inhibin complex(GO:0043511) inhibin A complex(GO:0043512) |
| 0.2 | 0.9 | GO:0032280 | symmetric synapse(GO:0032280) |
| 0.2 | 2.6 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.2 | 1.1 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.1 | 3.3 | GO:0005861 | troponin complex(GO:0005861) |
| 0.1 | 1.3 | GO:0032584 | growth cone membrane(GO:0032584) |
| 0.1 | 0.8 | GO:1990357 | terminal web(GO:1990357) |
| 0.1 | 1.3 | GO:0016600 | flotillin complex(GO:0016600) |
| 0.1 | 0.8 | GO:0042406 | extrinsic component of endoplasmic reticulum membrane(GO:0042406) |
| 0.1 | 2.1 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.1 | 2.1 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
| 0.1 | 1.5 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.1 | 3.3 | GO:0030057 | desmosome(GO:0030057) |
| 0.1 | 1.0 | GO:0097443 | sorting endosome(GO:0097443) |
| 0.1 | 1.7 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
| 0.1 | 1.0 | GO:1990023 | mitotic spindle midzone(GO:1990023) |
| 0.1 | 0.9 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.1 | 0.8 | GO:0000796 | condensin complex(GO:0000796) |
| 0.1 | 2.8 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.1 | 1.6 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.1 | 0.6 | GO:0098559 | cytoplasmic side of early endosome membrane(GO:0098559) |
| 0.1 | 0.4 | GO:0071817 | MMXD complex(GO:0071817) |
| 0.1 | 1.2 | GO:0035253 | ciliary rootlet(GO:0035253) |
| 0.1 | 2.3 | GO:0035098 | ESC/E(Z) complex(GO:0035098) |
| 0.1 | 1.6 | GO:0097440 | apical dendrite(GO:0097440) |
| 0.1 | 6.6 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
| 0.1 | 0.5 | GO:1990393 | 3M complex(GO:1990393) |
| 0.1 | 0.2 | GO:0033565 | ESCRT-0 complex(GO:0033565) |
| 0.1 | 1.5 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
| 0.1 | 0.5 | GO:0000923 | equatorial microtubule organizing center(GO:0000923) |
| 0.1 | 0.9 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.1 | 0.4 | GO:0097427 | microtubule bundle(GO:0097427) |
| 0.0 | 0.4 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 0.0 | 3.9 | GO:1904724 | tertiary granule lumen(GO:1904724) |
| 0.0 | 1.2 | GO:0005666 | DNA-directed RNA polymerase III complex(GO:0005666) |
| 0.0 | 8.3 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 1.0 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
| 0.0 | 0.3 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.0 | 0.3 | GO:0005854 | nascent polypeptide-associated complex(GO:0005854) |
| 0.0 | 0.2 | GO:0090543 | Flemming body(GO:0090543) |
| 0.0 | 0.5 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.0 | 1.9 | GO:0033017 | sarcoplasmic reticulum membrane(GO:0033017) |
| 0.0 | 0.4 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 0.1 | GO:0097208 | alveolar lamellar body(GO:0097208) |
| 0.0 | 0.2 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
| 0.0 | 0.3 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 1.4 | GO:0016592 | mediator complex(GO:0016592) |
| 0.0 | 0.1 | GO:0090571 | RNA polymerase II transcription repressor complex(GO:0090571) |
| 0.0 | 3.9 | GO:0005884 | actin filament(GO:0005884) |
| 0.0 | 0.8 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
| 0.0 | 0.6 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
| 0.0 | 0.5 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 0.4 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
| 0.0 | 0.7 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
| 0.0 | 0.1 | GO:0097255 | R2TP complex(GO:0097255) |
| 0.0 | 1.9 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 8.6 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.7 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.0 | 2.0 | GO:0030864 | cortical actin cytoskeleton(GO:0030864) |
| 0.0 | 0.2 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
| 0.0 | 0.6 | GO:0097381 | photoreceptor disc membrane(GO:0097381) |
| 0.0 | 0.6 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
| 0.0 | 0.5 | GO:0005721 | pericentric heterochromatin(GO:0005721) |
| 0.0 | 1.8 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.7 | GO:0016328 | lateral plasma membrane(GO:0016328) |
| 0.0 | 1.6 | GO:0005905 | clathrin-coated pit(GO:0005905) |
| 0.0 | 1.5 | GO:0045202 | synapse(GO:0045202) |
| 0.0 | 0.2 | GO:1990454 | L-type voltage-gated calcium channel complex(GO:1990454) |
| 0.0 | 1.5 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 0.2 | GO:0030897 | HOPS complex(GO:0030897) |
| 0.0 | 3.0 | GO:0030658 | transport vesicle membrane(GO:0030658) |
| 0.0 | 0.1 | GO:0016589 | NURF complex(GO:0016589) |
| 0.0 | 2.6 | GO:0001650 | fibrillar center(GO:0001650) |
| 0.0 | 0.4 | GO:0030673 | axolemma(GO:0030673) |
| 0.0 | 1.9 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.0 | 0.5 | GO:0005685 | U1 snRNP(GO:0005685) |
| 0.0 | 1.2 | GO:0044853 | plasma membrane raft(GO:0044853) |
| 0.0 | 0.5 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 1.4 | GO:0070821 | tertiary granule membrane(GO:0070821) |
| 0.0 | 1.4 | GO:0043679 | axon terminus(GO:0043679) |
| 0.0 | 2.1 | GO:0030027 | lamellipodium(GO:0030027) |
| 0.0 | 0.8 | GO:0031093 | platelet alpha granule lumen(GO:0031093) |
| 0.0 | 2.4 | GO:0005938 | cell cortex(GO:0005938) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.8 | 2.5 | GO:0008427 | calcium-dependent protein kinase inhibitor activity(GO:0008427) |
| 0.8 | 3.3 | GO:0034988 | Fc-gamma receptor I complex binding(GO:0034988) |
| 0.7 | 5.1 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
| 0.6 | 3.2 | GO:0004850 | uridine phosphorylase activity(GO:0004850) |
| 0.5 | 1.6 | GO:0043423 | 3-phosphoinositide-dependent protein kinase binding(GO:0043423) |
| 0.5 | 7.5 | GO:0005432 | calcium:sodium antiporter activity(GO:0005432) |
| 0.4 | 1.8 | GO:0035651 | AP-3 adaptor complex binding(GO:0035651) |
| 0.4 | 3.7 | GO:0043426 | MRF binding(GO:0043426) |
| 0.4 | 3.3 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
| 0.4 | 1.8 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
| 0.3 | 0.9 | GO:0061599 | molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599) |
| 0.3 | 0.9 | GO:0005173 | stem cell factor receptor binding(GO:0005173) |
| 0.3 | 1.8 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
| 0.3 | 1.6 | GO:0045569 | TRAIL binding(GO:0045569) |
| 0.2 | 1.5 | GO:0016941 | natriuretic peptide receptor activity(GO:0016941) |
| 0.2 | 3.2 | GO:0031014 | troponin T binding(GO:0031014) |
| 0.2 | 1.1 | GO:0005152 | interleukin-1 receptor antagonist activity(GO:0005152) |
| 0.2 | 0.8 | GO:0033829 | O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829) |
| 0.2 | 3.1 | GO:0045236 | CXCR chemokine receptor binding(GO:0045236) |
| 0.2 | 4.8 | GO:0017166 | vinculin binding(GO:0017166) |
| 0.2 | 1.0 | GO:0017108 | 5'-flap endonuclease activity(GO:0017108) |
| 0.2 | 1.1 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
| 0.2 | 0.9 | GO:0047374 | methylumbelliferyl-acetate deacetylase activity(GO:0047374) |
| 0.2 | 2.9 | GO:0050998 | nitric-oxide synthase binding(GO:0050998) |
| 0.2 | 0.7 | GO:0004771 | sterol esterase activity(GO:0004771) |
| 0.2 | 0.7 | GO:0008184 | glycogen phosphorylase activity(GO:0008184) |
| 0.2 | 0.9 | GO:0010465 | nerve growth factor receptor activity(GO:0010465) |
| 0.2 | 0.7 | GO:0008410 | CoA-transferase activity(GO:0008410) |
| 0.2 | 1.1 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.1 | 0.4 | GO:0016603 | glutaminyl-peptide cyclotransferase activity(GO:0016603) |
| 0.1 | 1.6 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.1 | 0.8 | GO:0052654 | branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656) |
| 0.1 | 0.8 | GO:0019136 | deoxynucleoside kinase activity(GO:0019136) |
| 0.1 | 0.9 | GO:1990254 | keratin filament binding(GO:1990254) |
| 0.1 | 1.6 | GO:0019871 | sodium channel inhibitor activity(GO:0019871) |
| 0.1 | 7.3 | GO:0005154 | epidermal growth factor receptor binding(GO:0005154) |
| 0.1 | 0.5 | GO:0003827 | alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827) |
| 0.1 | 0.4 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.1 | 1.0 | GO:0046920 | alpha-(1->3)-fucosyltransferase activity(GO:0046920) |
| 0.1 | 1.4 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
| 0.1 | 1.8 | GO:0034450 | ubiquitin-ubiquitin ligase activity(GO:0034450) |
| 0.1 | 1.6 | GO:0015250 | water channel activity(GO:0015250) |
| 0.1 | 1.9 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
| 0.1 | 2.6 | GO:0005528 | macrolide binding(GO:0005527) FK506 binding(GO:0005528) |
| 0.1 | 0.6 | GO:0008048 | calcium sensitive guanylate cyclase activator activity(GO:0008048) |
| 0.1 | 0.6 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
| 0.1 | 3.1 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
| 0.1 | 2.4 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
| 0.1 | 0.7 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.1 | 0.9 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.1 | 0.8 | GO:1990459 | transferrin receptor binding(GO:1990459) |
| 0.1 | 0.6 | GO:0035612 | AP-2 adaptor complex binding(GO:0035612) |
| 0.1 | 0.6 | GO:0009922 | fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338) |
| 0.1 | 0.5 | GO:1904929 | coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929) |
| 0.1 | 1.7 | GO:0050750 | low-density lipoprotein particle receptor binding(GO:0050750) |
| 0.1 | 4.3 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.1 | 1.3 | GO:0008349 | MAP kinase kinase kinase kinase activity(GO:0008349) |
| 0.1 | 0.5 | GO:0035614 | snRNA stem-loop binding(GO:0035614) |
| 0.1 | 0.4 | GO:0015501 | glutamate:sodium symporter activity(GO:0015501) |
| 0.1 | 0.6 | GO:0048495 | Roundabout binding(GO:0048495) |
| 0.1 | 0.5 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.1 | 0.2 | GO:0004971 | AMPA glutamate receptor activity(GO:0004971) |
| 0.1 | 1.4 | GO:0008353 | RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353) |
| 0.1 | 0.4 | GO:0003886 | DNA (cytosine-5-)-methyltransferase activity(GO:0003886) |
| 0.1 | 1.9 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
| 0.1 | 0.7 | GO:0016868 | intramolecular transferase activity, phosphotransferases(GO:0016868) |
| 0.1 | 0.4 | GO:0016167 | glial cell-derived neurotrophic factor receptor activity(GO:0016167) |
| 0.1 | 0.3 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.1 | 1.6 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 1.2 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
| 0.1 | 0.9 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.1 | 0.9 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
| 0.0 | 0.9 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.0 | 1.2 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.0 | 0.9 | GO:0032183 | SUMO binding(GO:0032183) |
| 0.0 | 1.6 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
| 0.0 | 1.1 | GO:0000339 | RNA cap binding(GO:0000339) |
| 0.0 | 0.6 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.0 | 0.5 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.0 | 0.4 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.0 | 1.2 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.0 | 0.3 | GO:0070290 | phospholipase D activity(GO:0004630) N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290) |
| 0.0 | 1.4 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.0 | 0.6 | GO:0009982 | pseudouridine synthase activity(GO:0009982) |
| 0.0 | 0.4 | GO:0035613 | RNA stem-loop binding(GO:0035613) |
| 0.0 | 3.0 | GO:0035064 | methylated histone binding(GO:0035064) |
| 0.0 | 0.9 | GO:0004012 | phospholipid-translocating ATPase activity(GO:0004012) |
| 0.0 | 0.2 | GO:0047057 | oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057) |
| 0.0 | 2.1 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.9 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.0 | 0.2 | GO:0004645 | phosphorylase activity(GO:0004645) |
| 0.0 | 0.8 | GO:0004029 | aldehyde dehydrogenase (NAD) activity(GO:0004029) |
| 0.0 | 0.8 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.5 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.0 | 3.0 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.0 | 0.9 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.0 | 0.2 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
| 0.0 | 1.5 | GO:0005246 | calcium channel regulator activity(GO:0005246) |
| 0.0 | 1.1 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |
| 0.0 | 0.1 | GO:1904455 | ubiquitin-specific protease activity involved in negative regulation of ERAD pathway(GO:1904455) |
| 0.0 | 0.2 | GO:0043533 | inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533) |
| 0.0 | 0.3 | GO:0004571 | mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571) |
| 0.0 | 1.1 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.0 | 0.1 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.0 | 0.3 | GO:0047498 | calcium-dependent phospholipase A2 activity(GO:0047498) |
| 0.0 | 1.5 | GO:0004712 | protein serine/threonine/tyrosine kinase activity(GO:0004712) |
| 0.0 | 0.2 | GO:0097322 | 7SK snRNA binding(GO:0097322) |
| 0.0 | 0.3 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
| 0.0 | 0.4 | GO:0005537 | mannose binding(GO:0005537) |
| 0.0 | 0.5 | GO:0022841 | potassium ion leak channel activity(GO:0022841) |
| 0.0 | 0.3 | GO:0015143 | urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702) |
| 0.0 | 0.1 | GO:0004951 | cholecystokinin receptor activity(GO:0004951) |
| 0.0 | 0.4 | GO:0015217 | ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217) |
| 0.0 | 0.1 | GO:0008417 | fucosyltransferase activity(GO:0008417) |
| 0.0 | 0.3 | GO:0034185 | apolipoprotein binding(GO:0034185) |
| 0.0 | 0.1 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
| 0.0 | 0.4 | GO:0019992 | diacylglycerol binding(GO:0019992) |
| 0.0 | 0.3 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
| 0.0 | 1.4 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.0 | 0.1 | GO:0001165 | RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165) |
| 0.0 | 0.4 | GO:0030506 | ankyrin binding(GO:0030506) |
| 0.0 | 0.1 | GO:0047888 | fatty acid peroxidase activity(GO:0047888) |
| 0.0 | 5.3 | GO:0061630 | ubiquitin protein ligase activity(GO:0061630) |
| 0.0 | 0.4 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.0 | 0.2 | GO:0004969 | histamine receptor activity(GO:0004969) |
| 0.0 | 0.9 | GO:0003899 | DNA-directed RNA polymerase activity(GO:0003899) |
| 0.0 | 2.0 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.4 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 1.7 | GO:0005198 | structural molecule activity(GO:0005198) |
| 0.0 | 1.2 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.0 | 1.0 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 0.2 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
| 0.0 | 0.6 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.0 | 8.1 | GO:0005525 | GTP binding(GO:0005525) |
| 0.0 | 0.1 | GO:0030172 | troponin C binding(GO:0030172) |
| 0.0 | 0.1 | GO:0005041 | low-density lipoprotein receptor activity(GO:0005041) |
| 0.0 | 0.2 | GO:0016783 | sulfurtransferase activity(GO:0016783) |
| 0.0 | 0.2 | GO:0017160 | Ral GTPase binding(GO:0017160) |
| 0.0 | 1.3 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.0 | 1.6 | GO:0001104 | RNA polymerase II transcription cofactor activity(GO:0001104) |
| 0.0 | 0.5 | GO:0008188 | neuropeptide receptor activity(GO:0008188) |
| 0.0 | 0.5 | GO:0070412 | R-SMAD binding(GO:0070412) |
| 0.0 | 0.1 | GO:0071532 | ankyrin repeat binding(GO:0071532) |
| 0.0 | 0.3 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.0 | 1.4 | GO:0008565 | protein transporter activity(GO:0008565) |
| 0.0 | 0.0 | GO:0051185 | coenzyme transporter activity(GO:0051185) |
| 0.0 | 0.1 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.0 | 0.4 | GO:0048365 | Rac GTPase binding(GO:0048365) |
| 0.0 | 2.1 | GO:0008201 | heparin binding(GO:0008201) |
| 0.0 | 0.1 | GO:0016742 | hydroxymethyl-, formyl- and related transferase activity(GO:0016742) |
Gene overrepresentation in C2:CP category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 6.0 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
| 0.1 | 9.6 | PID_NFAT_TFPATHWAY | Calcineurin-regulated NFAT-dependent transcription in lymphocytes |
| 0.1 | 6.8 | PID_SYNDECAN_4_PATHWAY | Syndecan-4-mediated signaling events |
| 0.1 | 3.9 | PID_WNT_NONCANONICAL_PATHWAY | Noncanonical Wnt signaling pathway |
| 0.1 | 0.9 | SA_TRKA_RECEPTOR | The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth. |
| 0.1 | 4.0 | PID_IL8_CXCR2_PATHWAY | IL8- and CXCR2-mediated signaling events |
| 0.1 | 2.5 | SA_PTEN_PATHWAY | PTEN is a tumor suppressor that dephosphorylates the lipid messenger phosphatidylinositol triphosphate. |
| 0.1 | 4.6 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
| 0.1 | 0.3 | PID_IL8_CXCR1_PATHWAY | IL8- and CXCR1-mediated signaling events |
| 0.1 | 0.6 | SA_G2_AND_M_PHASES | Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition. |
| 0.1 | 1.8 | PID_WNT_CANONICAL_PATHWAY | Canonical Wnt signaling pathway |
| 0.1 | 1.1 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
| 0.1 | 2.6 | PID_PS1_PATHWAY | Presenilin action in Notch and Wnt signaling |
| 0.1 | 1.6 | ST_G_ALPHA_S_PATHWAY | G alpha s Pathway |
| 0.1 | 0.6 | ST_JAK_STAT_PATHWAY | Jak-STAT Pathway |
| 0.0 | 2.9 | PID_ILK_PATHWAY | Integrin-linked kinase signaling |
| 0.0 | 1.6 | ST_WNT_CA2_CYCLIC_GMP_PATHWAY | Wnt/Ca2+/cyclic GMP signaling. |
| 0.0 | 2.7 | PID_NOTCH_PATHWAY | Notch signaling pathway |
| 0.0 | 2.2 | PID_AURORA_A_PATHWAY | Aurora A signaling |
| 0.0 | 3.9 | PID_E2F_PATHWAY | E2F transcription factor network |
| 0.0 | 2.0 | PID_CDC42_REG_PATHWAY | Regulation of CDC42 activity |
| 0.0 | 0.8 | PID_MYC_PATHWAY | C-MYC pathway |
| 0.0 | 1.6 | PID_INSULIN_PATHWAY | Insulin Pathway |
| 0.0 | 1.3 | PID_IL3_PATHWAY | IL3-mediated signaling events |
| 0.0 | 1.7 | NABA_BASEMENT_MEMBRANES | Genes encoding structural components of basement membranes |
| 0.0 | 1.0 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
| 0.0 | 2.2 | WNT_SIGNALING | Genes related to Wnt-mediated signal transduction |
| 0.0 | 0.6 | PID_CONE_PATHWAY | Visual signal transduction: Cones |
| 0.0 | 2.1 | PID_P73PATHWAY | p73 transcription factor network |
| 0.0 | 3.1 | PID_P53_DOWNSTREAM_PATHWAY | Direct p53 effectors |
| 0.0 | 1.2 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
| 0.0 | 0.9 | PID_KIT_PATHWAY | Signaling events mediated by Stem cell factor receptor (c-Kit) |
| 0.0 | 0.2 | PID_ECADHERIN_KERATINOCYTE_PATHWAY | E-cadherin signaling in keratinocytes |
| 0.0 | 0.6 | ST_P38_MAPK_PATHWAY | p38 MAPK Pathway |
| 0.0 | 0.4 | PID_S1P_S1P3_PATHWAY | S1P3 pathway |
| 0.0 | 0.5 | PID_NFAT_3PATHWAY | Role of Calcineurin-dependent NFAT signaling in lymphocytes |
| 0.0 | 0.9 | PID_TELOMERASE_PATHWAY | Regulation of Telomerase |
| 0.0 | 0.8 | PID_TGFBR_PATHWAY | TGF-beta receptor signaling |
| 0.0 | 0.1 | SIG_IL4RECEPTOR_IN_B_LYPHOCYTES | Genes related to IL4 rceptor signaling in B lymphocytes |
| 0.0 | 0.4 | PID_RAS_PATHWAY | Regulation of Ras family activation |
| 0.0 | 0.4 | PID_ATR_PATHWAY | ATR signaling pathway |
Gene overrepresentation in C2:CP:REACTOME category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 4.9 | REACTOME_CALNEXIN_CALRETICULIN_CYCLE | Genes involved in Calnexin/calreticulin cycle |
| 0.2 | 8.3 | REACTOME_PYRIMIDINE_METABOLISM | Genes involved in Pyrimidine metabolism |
| 0.2 | 4.5 | REACTOME_CELL_EXTRACELLULAR_MATRIX_INTERACTIONS | Genes involved in Cell-extracellular matrix interactions |
| 0.1 | 4.2 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
| 0.1 | 1.6 | REACTOME_PASSIVE_TRANSPORT_BY_AQUAPORINS | Genes involved in Passive Transport by Aquaporins |
| 0.1 | 1.9 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
| 0.1 | 2.2 | REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT | Genes involved in G2/M DNA damage checkpoint |
| 0.1 | 2.4 | REACTOME_PRE_NOTCH_PROCESSING_IN_GOLGI | Genes involved in Pre-NOTCH Processing in Golgi |
| 0.1 | 0.6 | REACTOME_CYTOKINE_SIGNALING_IN_IMMUNE_SYSTEM | Genes involved in Cytokine Signaling in Immune system |
| 0.1 | 4.1 | REACTOME_BASIGIN_INTERACTIONS | Genes involved in Basigin interactions |
| 0.1 | 1.2 | REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
| 0.1 | 3.7 | REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE | Genes involved in Sema4D induced cell migration and growth-cone collapse |
| 0.1 | 1.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE | Genes involved in Synthesis of PIPs at the early endosome membrane |
| 0.1 | 1.4 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
| 0.1 | 5.4 | REACTOME_STRIATED_MUSCLE_CONTRACTION | Genes involved in Striated Muscle Contraction |
| 0.1 | 1.7 | REACTOME_CHYLOMICRON_MEDIATED_LIPID_TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.1 | 1.6 | REACTOME_RAS_ACTIVATION_UOPN_CA2_INFUX_THROUGH_NMDA_RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.1 | 2.5 | REACTOME_PREFOLDIN_MEDIATED_TRANSFER_OF_SUBSTRATE_TO_CCT_TRIC | Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC |
| 0.1 | 0.9 | REACTOME_RETROGRADE_NEUROTROPHIN_SIGNALLING | Genes involved in Retrograde neurotrophin signalling |
| 0.1 | 0.8 | REACTOME_IRAK1_RECRUITS_IKK_COMPLEX | Genes involved in IRAK1 recruits IKK complex |
| 0.1 | 1.1 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
| 0.1 | 1.1 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
| 0.0 | 1.2 | REACTOME_ACTIVATED_TAK1_MEDIATES_P38_MAPK_ACTIVATION | Genes involved in activated TAK1 mediates p38 MAPK activation |
| 0.0 | 1.8 | REACTOME_KINESINS | Genes involved in Kinesins |
| 0.0 | 1.2 | REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT | Genes involved in Organic cation/anion/zwitterion transport |
| 0.0 | 2.2 | REACTOME_RAP1_SIGNALLING | Genes involved in Rap1 signalling |
| 0.0 | 1.6 | REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.0 | 0.6 | REACTOME_GLYCOPROTEIN_HORMONES | Genes involved in Glycoprotein hormones |
| 0.0 | 1.5 | REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING | Genes involved in Downregulation of TGF-beta receptor signaling |
| 0.0 | 3.1 | REACTOME_SCFSKP2_MEDIATED_DEGRADATION_OF_P27_P21 | Genes involved in SCF(Skp2)-mediated degradation of p27/p21 |
| 0.0 | 1.3 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
| 0.0 | 1.4 | REACTOME_ACTIVATED_NOTCH1_TRANSMITS_SIGNAL_TO_THE_NUCLEUS | Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus |
| 0.0 | 0.5 | REACTOME_SYNTHESIS_OF_SUBSTRATES_IN_N_GLYCAN_BIOSYTHESIS | Genes involved in Synthesis of substrates in N-glycan biosythesis |
| 0.0 | 0.5 | REACTOME_TANDEM_PORE_DOMAIN_POTASSIUM_CHANNELS | Genes involved in Tandem pore domain potassium channels |
| 0.0 | 0.7 | REACTOME_ENOS_ACTIVATION_AND_REGULATION | Genes involved in eNOS activation and regulation |
| 0.0 | 3.0 | REACTOME_ANTIVIRAL_MECHANISM_BY_IFN_STIMULATED_GENES | Genes involved in Antiviral mechanism by IFN-stimulated genes |
| 0.0 | 0.8 | REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM | Genes involved in Branched-chain amino acid catabolism |
| 0.0 | 0.6 | REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR | Genes involved in Signaling by constitutively active EGFR |
| 0.0 | 2.0 | REACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS | Genes involved in Metabolism of vitamins and cofactors |
| 0.0 | 0.2 | REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS | Genes involved in Apoptotic cleavage of cell adhesion proteins |
| 0.0 | 0.6 | REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 0.4 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 0.7 | REACTOME_SIGNALING_BY_HIPPO | Genes involved in Signaling by Hippo |
| 0.0 | 1.1 | REACTOME_GLYCOLYSIS | Genes involved in Glycolysis |
| 0.0 | 0.4 | REACTOME_GLYCOGEN_BREAKDOWN_GLYCOGENOLYSIS | Genes involved in Glycogen breakdown (glycogenolysis) |
| 0.0 | 0.6 | REACTOME_BETA_DEFENSINS | Genes involved in Beta defensins |
| 0.0 | 0.9 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |
| 0.0 | 0.7 | REACTOME_FORMATION_OF_FIBRIN_CLOT_CLOTTING_CASCADE | Genes involved in Formation of Fibrin Clot (Clotting Cascade) |
| 0.0 | 1.5 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |
| 0.0 | 0.5 | REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.2 | REACTOME_UNBLOCKING_OF_NMDA_RECEPTOR_GLUTAMATE_BINDING_AND_ACTIVATION | Genes involved in Unblocking of NMDA receptor, glutamate binding and activation |
| 0.0 | 0.2 | REACTOME_TRANS_GOLGI_NETWORK_VESICLE_BUDDING | Genes involved in trans-Golgi Network Vesicle Budding |
| 0.0 | 1.3 | REACTOME_ASPARAGINE_N_LINKED_GLYCOSYLATION | Genes involved in Asparagine N-linked glycosylation |
| 0.0 | 0.4 | REACTOME_INFLAMMASOMES | Genes involved in Inflammasomes |
| 0.0 | 0.8 | REACTOME_CHEMOKINE_RECEPTORS_BIND_CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 0.3 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
| 0.0 | 1.0 | REACTOME_LOSS_OF_NLP_FROM_MITOTIC_CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.0 | 1.1 | REACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION | Genes involved in Transcriptional Regulation of White Adipocyte Differentiation |
