Motif ID: FOXA3_FOXC2

Z-value: 0.516

Transcription factors associated with FOXA3_FOXC2:

Gene SymbolEntrez IDGene Name
FOXA3 ENSG00000170608.2 FOXA3
FOXC2 ENSG00000176692.4 FOXC2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
FOXC2hg19_v2_chr16_+_86600857_866009210.125.8e-01Click!
FOXA3hg19_v2_chr19_+_46367518_46367567-0.029.3e-01Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of FOXA3_FOXC2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr20_+_31823792 5.716 ENST00000375413.4
ENST00000354297.4
ENST00000375422.2
BPIFA1


BPI fold containing family A, member 1


chr11_+_27076764 2.339 ENST00000525090.1
BBOX1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase (gamma-butyrobetaine hydroxylase) 1
chr5_+_156712372 2.004 ENST00000541131.1
CYFIP2
cytoplasmic FMR1 interacting protein 2
chr20_+_31870927 1.786 ENST00000253354.1
BPIFB1
BPI fold containing family B, member 1
chr11_-_108464465 1.639 ENST00000525344.1
EXPH5
exophilin 5
chr11_-_108464321 1.371 ENST00000265843.4
EXPH5
exophilin 5
chr7_+_142829162 1.272 ENST00000291009.3
PIP
prolactin-induced protein
chr13_+_50589390 1.005 ENST00000360473.4
ENST00000312942.1
KCNRG

potassium channel regulator

chr1_-_207095324 0.897 ENST00000530505.1
ENST00000367091.3
ENST00000442471.2
FAIM3


Fas apoptotic inhibitory molecule 3


chr17_+_79953310 0.863 ENST00000582355.2
ASPSCR1
alveolar soft part sarcoma chromosome region, candidate 1
chr1_-_146696901 0.848 ENST00000369272.3
ENST00000441068.2
FMO5

flavin containing monooxygenase 5

chr20_+_9049682 0.842 ENST00000334005.3
ENST00000378473.3
PLCB4

phospholipase C, beta 4

chr17_+_72426891 0.717 ENST00000392627.1
GPRC5C
G protein-coupled receptor, family C, group 5, member C
chr13_-_36429763 0.704 ENST00000379893.1
DCLK1
doublecortin-like kinase 1
chr4_+_165675197 0.689 ENST00000515485.1
RP11-294O2.2
RP11-294O2.2
chr9_-_75567962 0.656 ENST00000297785.3
ENST00000376939.1
ALDH1A1

aldehyde dehydrogenase 1 family, member A1

chr13_-_39564993 0.640 ENST00000423210.1
STOML3
stomatin (EPB72)-like 3
chr1_+_104293028 0.625 ENST00000370079.3
AMY1C
amylase, alpha 1C (salivary)
chr13_-_86373536 0.599 ENST00000400286.2
SLITRK6
SLIT and NTRK-like family, member 6
chrX_+_9431324 0.596 ENST00000407597.2
ENST00000424279.1
ENST00000536365.1
ENST00000441088.1
ENST00000380961.1
ENST00000415293.1
TBL1X





transducin (beta)-like 1X-linked





chr10_-_21435488 0.578 ENST00000534331.1
ENST00000529198.1
ENST00000377118.4
C10orf113


chromosome 10 open reading frame 113


chr12_-_71551652 0.512 ENST00000546561.1
TSPAN8
tetraspanin 8
chr3_+_69985734 0.490 ENST00000314557.6
ENST00000394351.3
MITF

microphthalmia-associated transcription factor

chr12_+_59989918 0.477 ENST00000547379.1
ENST00000549465.1
SLC16A7

solute carrier family 16 (monocarboxylate transporter), member 7

chr4_+_165675269 0.466 ENST00000507311.1
RP11-294O2.2
RP11-294O2.2
chr20_+_52105495 0.459 ENST00000439873.2
AL354993.1
Cell growth-inhibiting protein 7; HCG1784586; Uncharacterized protein
chr1_+_104159999 0.458 ENST00000414303.2
ENST00000423678.1
AMY2A

amylase, alpha 2A (pancreatic)

chr3_-_45957088 0.455 ENST00000539217.1
LZTFL1
leucine zipper transcription factor-like 1
chr10_+_95848824 0.448 ENST00000371385.3
ENST00000371375.1
PLCE1

phospholipase C, epsilon 1

chr14_+_56585048 0.432 ENST00000267460.4
PELI2
pellino E3 ubiquitin protein ligase family member 2
chr2_-_175711133 0.424 ENST00000409597.1
ENST00000413882.1
CHN1

chimerin 1

chr1_-_207095212 0.420 ENST00000420007.2
FAIM3
Fas apoptotic inhibitory molecule 3
chr3_-_107941209 0.416 ENST00000492106.1
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr20_-_55841398 0.416 ENST00000395864.3
BMP7
bone morphogenetic protein 7
chr1_+_61547405 0.409 ENST00000371189.4
NFIA
nuclear factor I/A
chr12_-_76879852 0.385 ENST00000548341.1
OSBPL8
oxysterol binding protein-like 8
chr15_+_71185148 0.384 ENST00000443425.2
ENST00000560755.1
LRRC49

leucine rich repeat containing 49

chr3_-_45957534 0.361 ENST00000536047.1
LZTFL1
leucine zipper transcription factor-like 1
chr1_-_201096312 0.355 ENST00000449188.2
ASCL5
achaete-scute family bHLH transcription factor 5
chr1_+_87797351 0.311 ENST00000370542.1
LMO4
LIM domain only 4
chr1_+_244214577 0.307 ENST00000358704.4
ZBTB18
zinc finger and BTB domain containing 18
chr11_+_6897856 0.296 ENST00000379829.2
OR10A4
olfactory receptor, family 10, subfamily A, member 4
chr3_-_105588231 0.291 ENST00000545639.1
ENST00000394027.3
ENST00000438603.1
ENST00000447441.1
ENST00000443752.1
CBLB




Cbl proto-oncogene B, E3 ubiquitin protein ligase




chr3_-_107941230 0.288 ENST00000264538.3
IFT57
intraflagellar transport 57 homolog (Chlamydomonas)
chr17_+_7487146 0.285 ENST00000396501.4
ENST00000584378.1
ENST00000423172.2
ENST00000579445.1
ENST00000585217.1
ENST00000581380.1
MPDU1





mannose-P-dolichol utilization defect 1





chr9_-_28670283 0.282 ENST00000379992.2
LINGO2
leucine rich repeat and Ig domain containing 2
chr4_-_138453559 0.274 ENST00000511115.1
PCDH18
protocadherin 18
chr11_-_116708302 0.273 ENST00000375320.1
ENST00000359492.2
ENST00000375329.2
ENST00000375323.1
APOA1



apolipoprotein A-I



chr20_-_55841662 0.272 ENST00000395863.3
ENST00000450594.2
BMP7

bone morphogenetic protein 7

chr19_+_42806250 0.269 ENST00000598490.1
ENST00000341747.3
PRR19

proline rich 19

chr1_+_12806141 0.268 ENST00000288048.5
C1orf158
chromosome 1 open reading frame 158
chr14_-_25479811 0.263 ENST00000550887.1
STXBP6
syntaxin binding protein 6 (amisyn)
chr1_-_223308098 0.260 ENST00000342210.6
TLR5
toll-like receptor 5
chr7_+_116654935 0.260 ENST00000432298.1
ENST00000422922.1
ST7

suppression of tumorigenicity 7

chr17_+_72427477 0.255 ENST00000342648.5
ENST00000481232.1
GPRC5C

G protein-coupled receptor, family C, group 5, member C

chr10_-_49482907 0.251 ENST00000374201.3
ENST00000407470.4
FRMPD2

FERM and PDZ domain containing 2

chr5_-_41213607 0.247 ENST00000337836.5
ENST00000433294.1
C6

complement component 6

chr1_+_61548225 0.245 ENST00000371187.3
NFIA
nuclear factor I/A
chr12_-_39734783 0.240 ENST00000552961.1
KIF21A
kinesin family member 21A
chrX_+_10124977 0.223 ENST00000380833.4
CLCN4
chloride channel, voltage-sensitive 4
chr14_-_31926623 0.219 ENST00000356180.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr19_-_18902106 0.216 ENST00000542601.2
ENST00000425807.1
ENST00000222271.2
COMP


cartilage oligomeric matrix protein


chr3_+_69985792 0.214 ENST00000531774.1
MITF
microphthalmia-associated transcription factor
chr16_-_4664860 0.213 ENST00000587615.1
ENST00000587649.1
ENST00000590965.1
ENST00000591401.1
ENST00000283474.7
UBALD1




UBA-like domain containing 1




chr6_-_41715128 0.210 ENST00000356667.4
ENST00000373025.3
ENST00000425343.2
PGC


progastricsin (pepsinogen C)


chr14_+_74034310 0.208 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr2_-_188312971 0.208 ENST00000410068.1
ENST00000447403.1
ENST00000410102.1
CALCRL


calcitonin receptor-like


chr1_+_114471809 0.204 ENST00000426820.2
HIPK1
homeodomain interacting protein kinase 1
chr16_-_4665023 0.203 ENST00000591897.1
UBALD1
UBA-like domain containing 1
chr1_+_35225339 0.203 ENST00000339480.1
GJB4
gap junction protein, beta 4, 30.3kDa
chr14_-_101036119 0.193 ENST00000355173.2
BEGAIN
brain-enriched guanylate kinase-associated
chr1_+_18957500 0.193 ENST00000375375.3
PAX7
paired box 7
chr18_+_3449330 0.188 ENST00000549253.1
TGIF1
TGFB-induced factor homeobox 1
chr12_+_59989791 0.186 ENST00000552432.1
SLC16A7
solute carrier family 16 (monocarboxylate transporter), member 7
chr7_+_134832808 0.184 ENST00000275767.3
TMEM140
transmembrane protein 140
chr11_-_110561721 0.181 ENST00000357139.3
ARHGAP20
Rho GTPase activating protein 20
chr4_+_86396265 0.178 ENST00000395184.1
ARHGAP24
Rho GTPase activating protein 24
chr11_-_102401469 0.176 ENST00000260227.4
MMP7
matrix metallopeptidase 7 (matrilysin, uterine)
chr2_+_135596180 0.174 ENST00000283054.4
ENST00000392928.1
ACMSD

aminocarboxymuconate semialdehyde decarboxylase

chr17_+_4613776 0.173 ENST00000269260.2
ARRB2
arrestin, beta 2
chr18_-_53070913 0.172 ENST00000568186.1
ENST00000564228.1
TCF4

transcription factor 4

chr17_-_26694979 0.171 ENST00000438614.1
VTN
vitronectin
chr2_+_179318295 0.169 ENST00000442710.1
DFNB59
deafness, autosomal recessive 59
chr10_+_124320156 0.169 ENST00000338354.3
ENST00000344338.3
ENST00000330163.4
ENST00000368909.3
ENST00000368955.3
ENST00000368956.2
DMBT1





deleted in malignant brain tumors 1





chr17_-_26695013 0.169 ENST00000555059.2
CTB-96E2.2
Homeobox protein SEBOX
chr22_-_30867973 0.168 ENST00000402286.1
ENST00000401751.1
ENST00000539629.1
ENST00000403066.1
ENST00000215812.4
SEC14L3




SEC14-like 3 (S. cerevisiae)




chr17_-_26733179 0.165 ENST00000440501.1
ENST00000321666.5
SLC46A1

solute carrier family 46 (folate transporter), member 1

chr2_+_135596106 0.162 ENST00000356140.5
ACMSD
aminocarboxymuconate semialdehyde decarboxylase
chr10_+_124320195 0.160 ENST00000359586.6
DMBT1
deleted in malignant brain tumors 1
chr14_-_70263979 0.160 ENST00000216540.4
SLC10A1
solute carrier family 10 (sodium/bile acid cotransporter), member 1
chr12_-_92539614 0.160 ENST00000256015.3
BTG1
B-cell translocation gene 1, anti-proliferative
chr13_+_52598827 0.159 ENST00000521776.2
UTP14C
UTP14, U3 small nucleolar ribonucleoprotein, homolog C (yeast)
chr9_+_70856397 0.157 ENST00000360171.6
CBWD3
COBW domain containing 3
chr17_+_4613918 0.157 ENST00000574954.1
ENST00000346341.2
ENST00000572457.1
ENST00000381488.6
ENST00000412477.3
ENST00000571428.1
ENST00000575877.1
ARRB2






arrestin, beta 2






chr12_-_92536433 0.156 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79


chromosome 12 open reading frame 79


chr3_+_50712672 0.156 ENST00000266037.9
DOCK3
dedicator of cytokinesis 3
chr9_-_3469181 0.155 ENST00000366116.2
AL365202.1
Uncharacterized protein
chrX_+_135730373 0.154 ENST00000370628.2
CD40LG
CD40 ligand
chr1_+_101361782 0.154 ENST00000357650.4
SLC30A7
solute carrier family 30 (zinc transporter), member 7
chr22_+_46449674 0.152 ENST00000381051.2
FLJ27365
hsa-mir-4763
chr1_+_246729724 0.152 ENST00000366513.4
ENST00000366512.3
CNST

consortin, connexin sorting protein

chr5_+_40841276 0.151 ENST00000254691.5
CARD6
caspase recruitment domain family, member 6
chr17_+_8924837 0.151 ENST00000173229.2
NTN1
netrin 1
chr4_+_187148556 0.151 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1



kallikrein B, plasma (Fletcher factor) 1



chr16_+_69958887 0.149 ENST00000568684.1
WWP2
WW domain containing E3 ubiquitin protein ligase 2
chr16_+_20775358 0.149 ENST00000440284.2
ACSM3
acyl-CoA synthetase medium-chain family member 3
chr9_-_70490107 0.147 ENST00000377395.4
ENST00000429800.2
ENST00000430059.2
ENST00000377384.1
ENST00000382405.3
CBWD5




COBW domain containing 5




chr3_+_119316689 0.147 ENST00000273371.4
PLA1A
phospholipase A1 member A
chr14_+_105267250 0.146 ENST00000342537.7
ZBTB42
zinc finger and BTB domain containing 42
chr4_-_70080449 0.146 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr16_-_15474904 0.144 ENST00000534094.1
NPIPA5
nuclear pore complex interacting protein family, member A5
chrX_+_135730297 0.144 ENST00000370629.2
CD40LG
CD40 ligand
chr8_+_19171128 0.143 ENST00000265807.3
SH2D4A
SH2 domain containing 4A
chr3_+_119316721 0.139 ENST00000488919.1
ENST00000495992.1
PLA1A

phospholipase A1 member A

chr17_-_66951474 0.138 ENST00000269080.2
ABCA8
ATP-binding cassette, sub-family A (ABC1), member 8
chr3_+_132316081 0.137 ENST00000249887.2
ACKR4
atypical chemokine receptor 4
chr5_+_161494770 0.137 ENST00000414552.2
ENST00000361925.4
GABRG2

gamma-aminobutyric acid (GABA) A receptor, gamma 2

chr10_+_123923105 0.135 ENST00000368999.1
TACC2
transforming, acidic coiled-coil containing protein 2
chrX_+_65382381 0.134 ENST00000519389.1
HEPH
hephaestin
chr1_+_29563011 0.134 ENST00000345512.3
ENST00000373779.3
ENST00000356870.3
ENST00000323874.8
ENST00000428026.2
ENST00000460170.2
PTPRU





protein tyrosine phosphatase, receptor type, U





chr15_+_96869165 0.134 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr13_-_99910673 0.132 ENST00000397473.2
ENST00000397470.2
GPR18

G protein-coupled receptor 18

chr16_+_14802801 0.132 ENST00000526520.1
ENST00000531598.2
NPIPA3

nuclear pore complex interacting protein family, member A3

chr17_-_6947225 0.131 ENST00000574600.1
ENST00000308009.1
ENST00000447225.1
SLC16A11


solute carrier family 16, member 11


chr3_-_187455680 0.130 ENST00000438077.1
BCL6
B-cell CLL/lymphoma 6
chr10_-_31288398 0.129 ENST00000538351.2
ZNF438
zinc finger protein 438
chr4_+_86396321 0.125 ENST00000503995.1
ARHGAP24
Rho GTPase activating protein 24
chr8_+_95908041 0.125 ENST00000396113.1
ENST00000519136.1
NDUFAF6

NADH dehydrogenase (ubiquinone) complex I, assembly factor 6

chr3_-_114343039 0.125 ENST00000481632.1
ZBTB20
zinc finger and BTB domain containing 20
chr3_-_193096600 0.123 ENST00000446087.1
ENST00000342358.4
ATP13A5

ATPase type 13A5

chr6_+_52051171 0.123 ENST00000340057.1
IL17A
interleukin 17A
chr1_-_246729544 0.123 ENST00000544618.1
ENST00000366514.4
TFB2M

transcription factor B2, mitochondrial

chr14_-_31926701 0.121 ENST00000310850.4
DTD2
D-tyrosyl-tRNA deacylase 2 (putative)
chr3_+_148545586 0.121 ENST00000282957.4
ENST00000468341.1
CPB1

carboxypeptidase B1 (tissue)

chr5_+_161494521 0.121 ENST00000356592.3
GABRG2
gamma-aminobutyric acid (GABA) A receptor, gamma 2
chr2_+_175260451 0.120 ENST00000458563.1
ENST00000409673.3
ENST00000272732.6
ENST00000435964.1
SCRN3



secernin 3



chr4_-_140223670 0.120 ENST00000394228.1
ENST00000539387.1
NDUFC1

NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa

chr5_+_140787600 0.118 ENST00000520790.1
PCDHGB6
protocadherin gamma subfamily B, 6
chr4_-_140223614 0.116 ENST00000394223.1
NDUFC1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa
chr16_-_3350614 0.116 ENST00000268674.2
TIGD7
tigger transposable element derived 7
chr3_+_171561127 0.115 ENST00000334567.5
ENST00000450693.1
TMEM212

transmembrane protein 212

chr14_-_24664540 0.114 ENST00000530563.1
ENST00000528895.1
ENST00000528669.1
ENST00000532632.1
TM9SF1



transmembrane 9 superfamily member 1



chrX_+_24167746 0.113 ENST00000428571.1
ENST00000539115.1
ZFX

zinc finger protein, X-linked

chr13_+_73629107 0.113 ENST00000539231.1
KLF5
Kruppel-like factor 5 (intestinal)
chr6_+_44310421 0.112 ENST00000288390.2
SPATS1
spermatogenesis associated, serine-rich 1
chr15_+_28624878 0.110 ENST00000450328.2
GOLGA8F
golgin A8 family, member F
chr19_+_47421933 0.109 ENST00000404338.3
ARHGAP35
Rho GTPase activating protein 35
chr4_+_146403912 0.107 ENST00000507367.1
ENST00000394092.2
ENST00000515385.1
SMAD1


SMAD family member 1


chr21_-_43786634 0.107 ENST00000291527.2
TFF1
trefoil factor 1
chr8_+_95907993 0.107 ENST00000523378.1
NDUFAF6
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr7_+_151038850 0.107 ENST00000355851.4
ENST00000566856.1
ENST00000470229.1
NUB1


negative regulator of ubiquitin-like proteins 1


chr2_-_227050079 0.105 ENST00000423838.1
AC068138.1
AC068138.1
chr1_+_43855560 0.104 ENST00000562955.1
SZT2
seizure threshold 2 homolog (mouse)
chr4_-_11431389 0.103 ENST00000002596.5
HS3ST1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr1_-_150602035 0.102 ENST00000503241.1
ENST00000369016.4
ENST00000339643.5
ENST00000271690.8
ENST00000356527.5
ENST00000362052.7
ENST00000503345.1
ENST00000369014.5
ENST00000369009.3
ENSA








endosulfine alpha








chr19_-_46088068 0.101 ENST00000263275.4
ENST00000323060.3
OPA3

optic atrophy 3 (autosomal recessive, with chorea and spastic paraplegia)

chr18_+_61575200 0.098 ENST00000238508.3
SERPINB10
serpin peptidase inhibitor, clade B (ovalbumin), member 10
chr6_+_44310376 0.098 ENST00000515220.1
ENST00000323108.8
SPATS1

spermatogenesis associated, serine-rich 1

chr14_+_56127989 0.096 ENST00000555573.1
KTN1
kinectin 1 (kinesin receptor)
chrX_+_24167828 0.094 ENST00000379188.3
ENST00000419690.1
ENST00000379177.1
ENST00000304543.5
ZFX



zinc finger protein, X-linked



chr14_-_21562648 0.092 ENST00000555270.1
ZNF219
zinc finger protein 219
chr17_-_26697304 0.091 ENST00000536498.1
VTN
vitronectin
chr1_+_114471972 0.091 ENST00000369559.4
ENST00000369554.2
HIPK1

homeodomain interacting protein kinase 1

chr17_-_39324424 0.090 ENST00000391356.2
KRTAP4-3
keratin associated protein 4-3
chrX_-_133792480 0.090 ENST00000359237.4
PLAC1
placenta-specific 1
chr15_+_60296421 0.086 ENST00000396057.4
FOXB1
forkhead box B1
chr12_-_122018346 0.086 ENST00000377069.4
KDM2B
lysine (K)-specific demethylase 2B
chr4_-_87028478 0.085 ENST00000515400.1
ENST00000395157.3
MAPK10

mitogen-activated protein kinase 10

chrX_-_80457385 0.084 ENST00000451455.1
ENST00000436386.1
ENST00000358130.2
HMGN5


high mobility group nucleosome binding domain 5


chr1_-_150669500 0.082 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr12_+_58087901 0.082 ENST00000315970.7
ENST00000547079.1
ENST00000439210.2
ENST00000389146.6
ENST00000413095.2
ENST00000551035.1
ENST00000257966.8
ENST00000435406.2
ENST00000550372.1
ENST00000389142.5
OS9









osteosarcoma amplified 9, endoplasmic reticulum lectin









chr6_+_146348810 0.082 ENST00000492807.2
GRM1
glutamate receptor, metabotropic 1
chr12_+_48516357 0.081 ENST00000549022.1
ENST00000547587.1
ENST00000312352.7
PFKM


phosphofructokinase, muscle


chr17_-_39183452 0.081 ENST00000361883.5
KRTAP1-5
keratin associated protein 1-5
chr15_-_40600026 0.079 ENST00000456256.2
ENST00000557821.1
PLCB2

phospholipase C, beta 2

chr3_+_137728842 0.079 ENST00000183605.5
CLDN18
claudin 18
chr1_+_159141397 0.078 ENST00000368124.4
ENST00000368125.4
ENST00000416746.1
CADM3


cell adhesion molecule 3


chr12_-_48099754 0.077 ENST00000380650.4
RPAP3
RNA polymerase II associated protein 3
chr13_+_95364963 0.074 ENST00000438290.2
SOX21-AS1
SOX21 antisense RNA 1 (head to head)
chr1_-_150669604 0.073 ENST00000427665.1
ENST00000540514.1
GOLPH3L

golgi phosphoprotein 3-like

chr2_+_169659121 0.073 ENST00000397206.2
ENST00000397209.2
ENST00000421711.2
NOSTRIN


nitric oxide synthase trafficking


chr22_-_39268308 0.073 ENST00000407418.3
CBX6
chromobox homolog 6
chr14_-_74551096 0.073 ENST00000350259.4
ALDH6A1
aldehyde dehydrogenase 6 family, member A1
chr6_+_161123270 0.073 ENST00000366924.2
ENST00000308192.9
ENST00000418964.1
PLG


plasminogen


chr6_-_165989936 0.072 ENST00000354448.4
PDE10A
phosphodiesterase 10A
chr2_+_169658928 0.070 ENST00000317647.7
ENST00000445023.2
NOSTRIN

nitric oxide synthase trafficking

chr6_+_10528560 0.070 ENST00000379597.3
GCNT2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
chr12_-_48099773 0.070 ENST00000432584.3
ENST00000005386.3
RPAP3

RNA polymerase II associated protein 3

chr6_+_21666633 0.070 ENST00000606851.1
CASC15
cancer susceptibility candidate 15 (non-protein coding)
chr6_+_146348782 0.070 ENST00000361719.2
ENST00000392299.2
GRM1

glutamate receptor, metabotropic 1

chr17_-_79212825 0.070 ENST00000374769.2
ENTHD2
ENTH domain containing 2
chr2_+_109223595 0.068 ENST00000410093.1
LIMS1
LIM and senescent cell antigen-like domains 1
chr1_-_43855479 0.068 ENST00000290663.6
ENST00000372457.4
MED8

mediator complex subunit 8

chr16_+_84801852 0.067 ENST00000569925.1
ENST00000567526.1
USP10

ubiquitin specific peptidase 10

chr1_-_54405773 0.066 ENST00000371376.1
HSPB11
heat shock protein family B (small), member 11
chr7_-_141673573 0.065 ENST00000547270.1
TAS2R38
taste receptor, type 2, member 38
chr1_+_150488205 0.065 ENST00000416894.1
LINC00568
long intergenic non-protein coding RNA 568
chr4_-_88450244 0.065 ENST00000503414.1
SPARCL1
SPARC-like 1 (hevin)
chr20_-_1974692 0.064 ENST00000217305.2
ENST00000539905.1
PDYN

prodynorphin

chr19_-_47157914 0.064 ENST00000300875.4
DACT3
dishevelled-binding antagonist of beta-catenin 3

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 5.7 GO:0042710 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.3 0.8 GO:1903568 negative regulation of protein localization to cilium(GO:1903565) regulation of protein localization to ciliary membrane(GO:1903567) negative regulation of protein localization to ciliary membrane(GO:1903568)
0.2 1.8 GO:0034144 negative regulation of toll-like receptor 4 signaling pathway(GO:0034144)
0.2 2.3 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.2 1.9 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.2 0.7 GO:0072134 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme morphogenesis(GO:0072134) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) allantois development(GO:1905069)
0.2 0.7 GO:0006001 fructose catabolic process(GO:0006001) fructose catabolic process to hydroxyacetone phosphate and glyceraldehyde-3-phosphate(GO:0061624)
0.1 3.0 GO:0003334 keratinocyte development(GO:0003334)
0.1 0.3 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.1 0.6 GO:0060005 vestibular reflex(GO:0060005)
0.1 0.7 GO:0006848 pyruvate transport(GO:0006848) pyruvate transmembrane transport(GO:1901475)
0.1 0.3 GO:0010903 negative regulation of very-low-density lipoprotein particle remodeling(GO:0010903)
0.1 0.4 GO:0006651 diacylglycerol biosynthetic process(GO:0006651)
0.1 0.3 GO:0002032 desensitization of G-protein coupled receptor protein signaling pathway by arrestin(GO:0002032)
0.1 0.5 GO:0044245 polysaccharide digestion(GO:0044245)
0.1 0.2 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 1.0 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.1 0.1 GO:0060738 epithelial-mesenchymal signaling involved in prostate gland development(GO:0060738)
0.1 0.2 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.0 0.3 GO:0060235 lens induction in camera-type eye(GO:0060235)
0.0 0.3 GO:0019805 quinolinate biosynthetic process(GO:0019805) 'de novo' NAD biosynthetic process(GO:0034627)
0.0 0.1 GO:0032764 negative regulation of mast cell cytokine production(GO:0032764)
0.0 1.3 GO:0070233 negative regulation of T cell apoptotic process(GO:0070233)
0.0 0.2 GO:0051958 methotrexate transport(GO:0051958)
0.0 0.4 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.6 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.2 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.1 GO:0009956 radial pattern formation(GO:0009956)
0.0 0.3 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.3 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.0 0.1 GO:0061030 axon target recognition(GO:0007412) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.1 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.7 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0093001 glycolysis from storage polysaccharide through glucose-1-phosphate(GO:0093001)
0.0 0.2 GO:0032488 Cdc42 protein signal transduction(GO:0032488)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.0 0.8 GO:0060972 left/right pattern formation(GO:0060972)
0.0 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.1 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.0 0.1 GO:0021592 midbrain-hindbrain boundary morphogenesis(GO:0021555) fourth ventricle development(GO:0021592)
0.0 0.2 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.8 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.2 GO:0061088 regulation of sequestering of zinc ion(GO:0061088)
0.0 0.2 GO:0042996 regulation of Golgi to plasma membrane protein transport(GO:0042996)
0.0 0.0 GO:0044537 regulation of circulating fibrinogen levels(GO:0044537)
0.0 0.3 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.2 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.3 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.2 GO:0048194 Golgi vesicle budding(GO:0048194)
0.0 0.1 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747)
0.0 0.1 GO:0015722 canalicular bile acid transport(GO:0015722)
0.0 0.7 GO:0030318 melanocyte differentiation(GO:0030318)
0.0 0.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0071847 TNFSF11-mediated signaling pathway(GO:0071847)
0.0 0.1 GO:0042908 xenobiotic transport(GO:0042908)
0.0 0.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.4 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 0.1 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.0 0.1 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.3 GO:0036150 phosphatidylserine acyl-chain remodeling(GO:0036150)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.3 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237) alphav-beta3 integrin-vitronectin complex(GO:0071062)
0.1 0.3 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.1 0.7 GO:0044292 dendrite terminus(GO:0044292)
0.0 0.2 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.1 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.0 0.1 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0000836 Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.2 GO:0042589 zymogen granule membrane(GO:0042589)
0.0 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.3 GO:0008336 gamma-butyrobetaine dioxygenase activity(GO:0008336)
0.2 0.7 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.1 0.7 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.5 GO:0016160 amylase activity(GO:0016160)
0.1 0.3 GO:0051499 D-aminoacyl-tRNA deacylase activity(GO:0051499) D-tyrosyl-tRNA(Tyr) deacylase activity(GO:0051500)
0.1 0.3 GO:0031859 platelet activating factor receptor binding(GO:0031859)
0.1 0.8 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 1.3 GO:0019864 IgG binding(GO:0019864)
0.1 0.3 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.1 0.7 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.2 GO:0015350 methotrexate transporter activity(GO:0015350)
0.0 0.3 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739)
0.0 1.3 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.2 GO:0071253 connexin binding(GO:0071253)
0.0 0.0 GO:0033858 N-acetylgalactosamine kinase activity(GO:0033858)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.0 GO:0045145 single-stranded DNA 5'-3' exodeoxyribonuclease activity(GO:0045145)
0.0 0.1 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.6 GO:0070888 E-box binding(GO:0070888)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.1 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.1 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 2.6 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.3 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.0 0.0 GO:0017098 sulfonylurea receptor binding(GO:0017098)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.8 PID_ALK2_PATHWAY ALK2 signaling events
0.0 1.9 PID_ECADHERIN_STABILIZATION_PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.1 PID_EPHA2_FWD_PATHWAY EPHA2 forward signaling
0.0 1.0 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 0.3 PID_NFKAPPAB_ATYPICAL_PATHWAY Atypical NF-kappaB pathway
0.0 0.9 ST_G_ALPHA_I_PATHWAY G alpha i Pathway
0.0 0.6 PID_CD40_PATHWAY CD40/CD40L signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME_DIGESTION_OF_DIETARY_CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.7 REACTOME_ETHANOL_OXIDATION Genes involved in Ethanol oxidation
0.0 0.7 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.6 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME_ABCA_TRANSPORTERS_IN_LIPID_HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME_ROLE_OF_SECOND_MESSENGERS_IN_NETRIN1_SIGNALING Genes involved in Role of second messengers in netrin-1 signaling