Motif ID: GATA1_GATA4

Z-value: 0.916

Transcription factors associated with GATA1_GATA4:

Gene SymbolEntrez IDGene Name
GATA1 ENSG00000102145.9 GATA1
GATA4 ENSG00000136574.13 GATA4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GATA1hg19_v2_chrX_+_48644962_486449830.573.5e-03Click!
GATA4hg19_v2_chr8_+_11534462_115344750.481.6e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1_GATA4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_153113927 3.702 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr9_+_33795533 3.595 ENST00000379405.3
PRSS3
protease, serine, 3
chr2_+_102928009 3.523 ENST00000404917.2
ENST00000447231.1
IL1RL1

interleukin 1 receptor-like 1

chr1_-_24469602 3.389 ENST00000270800.1
IL22RA1
interleukin 22 receptor, alpha 1
chr12_+_4385230 3.032 ENST00000536537.1
CCND2
cyclin D2
chr4_-_159094194 2.567 ENST00000592057.1
ENST00000585682.1
ENST00000393807.5
FAM198B


family with sequence similarity 198, member B


chr19_-_51487071 1.935 ENST00000391807.1
ENST00000593904.1
KLK7

kallikrein-related peptidase 7

chr4_-_103266355 1.873 ENST00000424970.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chr19_-_51487282 1.831 ENST00000595820.1
ENST00000597707.1
ENST00000336317.4
KLK7


kallikrein-related peptidase 7


chrX_+_135278908 1.661 ENST00000539015.1
ENST00000370683.1
FHL1

four and a half LIM domains 1

chr8_+_124194875 1.629 ENST00000522648.1
ENST00000276699.6
FAM83A

family with sequence similarity 83, member A

chr17_+_74381343 1.574 ENST00000392496.3
SPHK1
sphingosine kinase 1
chr8_+_124194752 1.562 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr3_-_98312548 1.493 ENST00000264193.2
CPOX
coproporphyrinogen oxidase
chr1_-_153029980 1.446 ENST00000392653.2
SPRR2A
small proline-rich protein 2A
chr1_-_153013588 1.401 ENST00000360379.3
SPRR2D
small proline-rich protein 2D
chr3_-_47950745 1.360 ENST00000429422.1
MAP4
microtubule-associated protein 4
chrX_+_135279179 1.350 ENST00000370676.3
FHL1
four and a half LIM domains 1
chr2_-_165424973 1.345 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr12_+_15699286 1.287 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO



protein tyrosine phosphatase, receptor type, O



chr7_+_100547156 1.284 ENST00000379458.4
MUC3A
Protein LOC100131514
chrX_+_56258844 1.249 ENST00000374928.3
KLF8
Kruppel-like factor 8
chr2_-_24307162 1.222 ENST00000413037.1
ENST00000407482.1
TP53I3

tumor protein p53 inducible protein 3

chr7_-_99277610 1.219 ENST00000343703.5
ENST00000222982.4
ENST00000439761.1
ENST00000339843.2
CYP3A5



cytochrome P450, family 3, subfamily A, polypeptide 5



chr2_+_174219548 1.208 ENST00000347703.3
ENST00000392567.2
ENST00000306721.3
ENST00000410101.3
ENST00000410019.3
CDCA7




cell division cycle associated 7




chr9_+_34652164 1.140 ENST00000441545.2
ENST00000553620.1
IL11RA

interleukin 11 receptor, alpha

chr16_+_70680439 1.087 ENST00000288098.2
IL34
interleukin 34
chr4_-_103266219 1.074 ENST00000394833.2
SLC39A8
solute carrier family 39 (zinc transporter), member 8
chrX_+_152082969 1.067 ENST00000535861.1
ENST00000539731.1
ENST00000449285.2
ENST00000318504.7
ENST00000324823.6
ENST00000370268.4
ENST00000370270.2
ZNF185






zinc finger protein 185 (LIM domain)






chr19_+_10397621 1.047 ENST00000380770.3
ICAM4
intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)
chr19_+_10397648 1.019 ENST00000340992.4
ENST00000393717.2
ICAM4

intercellular adhesion molecule 4 (Landsteiner-Wiener blood group)

chr4_-_68749745 1.018 ENST00000283916.6
TMPRSS11D
transmembrane protease, serine 11D
chr22_-_20231207 1.005 ENST00000425986.1
RTN4R
reticulon 4 receptor
chr9_-_114937465 0.990 ENST00000355396.3
SUSD1
sushi domain containing 1
chr9_+_139557360 0.986 ENST00000308874.7
ENST00000406555.3
ENST00000492862.2
EGFL7


EGF-like-domain, multiple 7


chr6_+_12290586 0.979 ENST00000379375.5
EDN1
endothelin 1
chr5_+_159848807 0.955 ENST00000352433.5
PTTG1
pituitary tumor-transforming 1
chr5_-_39219705 0.942 ENST00000351578.6
FYB
FYN binding protein
chr1_-_94050668 0.942 ENST00000539242.1
BCAR3
breast cancer anti-estrogen resistance 3
chr9_+_33240157 0.929 ENST00000379721.3
SPINK4
serine peptidase inhibitor, Kazal type 4
chr1_-_153521597 0.929 ENST00000368712.1
S100A3
S100 calcium binding protein A3
chr1_-_201368653 0.929 ENST00000367313.3
LAD1
ladinin 1
chr18_+_19749386 0.924 ENST00000269216.3
GATA6
GATA binding protein 6
chr15_-_34610962 0.916 ENST00000290209.5
SLC12A6
solute carrier family 12 (potassium/chloride transporter), member 6
chr17_-_73840415 0.909 ENST00000592386.1
ENST00000412096.2
ENST00000586147.1
UNC13D


unc-13 homolog D (C. elegans)


chr12_-_52845910 0.903 ENST00000252252.3
KRT6B
keratin 6B
chr9_-_114937543 0.889 ENST00000374264.2
ENST00000374263.3
SUSD1

sushi domain containing 1

chr17_+_33914276 0.884 ENST00000592545.1
ENST00000538556.1
ENST00000312678.8
ENST00000589344.1
AP2B1



adaptor-related protein complex 2, beta 1 subunit



chr2_+_27719697 0.882 ENST00000264717.2
ENST00000424318.2
GCKR

glucokinase (hexokinase 4) regulator

chr1_-_201368707 0.876 ENST00000391967.2
LAD1
ladinin 1
chrX_+_44703249 0.861 ENST00000339042.4
DUSP21
dual specificity phosphatase 21
chr2_-_69098566 0.856 ENST00000295379.1
BMP10
bone morphogenetic protein 10
chr7_-_50860565 0.849 ENST00000403097.1
GRB10
growth factor receptor-bound protein 10
chrX_+_107288239 0.817 ENST00000217957.5
VSIG1
V-set and immunoglobulin domain containing 1
chr4_-_68749699 0.806 ENST00000545541.1
TMPRSS11D
transmembrane protease, serine 11D
chrX_+_107288197 0.795 ENST00000415430.3
VSIG1
V-set and immunoglobulin domain containing 1
chr10_+_71075552 0.792 ENST00000298649.3
HK1
hexokinase 1
chr14_-_94421923 0.790 ENST00000555507.1
ASB2
ankyrin repeat and SOCS box containing 2
chr1_-_167487758 0.787 ENST00000362089.5
CD247
CD247 molecule
chr7_+_142457315 0.782 ENST00000486171.1
ENST00000311737.7
PRSS1

protease, serine, 1 (trypsin 1)

chr6_-_107235287 0.779 ENST00000436659.1
ENST00000428750.1
ENST00000427903.1
RP1-60O19.1


RP1-60O19.1


chr5_-_39270725 0.779 ENST00000512138.1
ENST00000512982.1
ENST00000540520.1
FYB


FYN binding protein


chr5_+_147443534 0.771 ENST00000398454.1
ENST00000359874.3
ENST00000508733.1
ENST00000256084.7
SPINK5



serine peptidase inhibitor, Kazal type 5



chr4_-_120243545 0.769 ENST00000274024.3
FABP2
fatty acid binding protein 2, intestinal
chr9_-_114937676 0.761 ENST00000374270.3
SUSD1
sushi domain containing 1
chr5_-_39219641 0.761 ENST00000509072.1
ENST00000504542.1
ENST00000505428.1
ENST00000506557.1
FYB



FYN binding protein



chr1_-_153521714 0.749 ENST00000368713.3
S100A3
S100 calcium binding protein A3
chr9_+_132099158 0.746 ENST00000444125.1
RP11-65J3.1
RP11-65J3.1
chr8_-_91095099 0.735 ENST00000265431.3
CALB1
calbindin 1, 28kDa
chr1_-_204116078 0.735 ENST00000367198.2
ENST00000452983.1
ETNK2

ethanolamine kinase 2

chr17_-_38938786 0.734 ENST00000301656.3
KRT27
keratin 27
chr10_-_48416849 0.734 ENST00000249598.1
GDF2
growth differentiation factor 2
chr4_-_48082192 0.733 ENST00000507351.1
TXK
TXK tyrosine kinase
chr17_+_19314505 0.728 ENST00000461366.1
RNF112
ring finger protein 112
chr18_+_61445007 0.727 ENST00000447428.1
ENST00000546027.1
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr14_+_85996471 0.717 ENST00000330753.4
FLRT2
fibronectin leucine rich transmembrane protein 2
chr11_-_125550764 0.714 ENST00000527795.1
ACRV1
acrosomal vesicle protein 1
chr11_-_59612969 0.690 ENST00000541311.1
ENST00000257248.2
GIF

gastric intrinsic factor (vitamin B synthesis)

chr3_+_172468505 0.687 ENST00000427830.1
ENST00000417960.1
ENST00000428567.1
ENST00000366090.2
ENST00000426894.1
ECT2




epithelial cell transforming sequence 2 oncogene




chr12_+_9144626 0.686 ENST00000543895.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr17_+_1958388 0.685 ENST00000399849.3
HIC1
hypermethylated in cancer 1
chr6_-_131277510 0.682 ENST00000525193.1
ENST00000527659.1
EPB41L2

erythrocyte membrane protein band 4.1-like 2

chr6_+_47666275 0.673 ENST00000327753.3
ENST00000283303.2
GPR115

G protein-coupled receptor 115

chr11_-_3859089 0.665 ENST00000396979.1
RHOG
ras homolog family member G
chr1_-_205912577 0.661 ENST00000367135.3
ENST00000367134.2
SLC26A9

solute carrier family 26 (anion exchanger), member 9

chr12_+_9102632 0.654 ENST00000539240.1
KLRG1
killer cell lectin-like receptor subfamily G, member 1
chr12_+_4430371 0.654 ENST00000179259.4
C12orf5
chromosome 12 open reading frame 5
chr11_-_124311054 0.652 ENST00000328064.2
OR8B8
olfactory receptor, family 8, subfamily B, member 8
chr2_-_228028829 0.648 ENST00000396625.3
ENST00000329662.7
COL4A4

collagen, type IV, alpha 4

chr14_+_60975644 0.632 ENST00000327720.5
SIX6
SIX homeobox 6
chrX_+_38211777 0.631 ENST00000039007.4
OTC
ornithine carbamoyltransferase
chrX_+_99899180 0.629 ENST00000373004.3
SRPX2
sushi-repeat containing protein, X-linked 2
chr2_+_192543153 0.627 ENST00000425611.2
NABP1
nucleic acid binding protein 1
chr1_+_25598872 0.624 ENST00000328664.4
RHD
Rh blood group, D antigen
chr12_+_53662073 0.622 ENST00000553219.1
ENST00000257934.4
ESPL1

extra spindle pole bodies homolog 1 (S. cerevisiae)

chr11_-_125550726 0.619 ENST00000315608.3
ENST00000530048.1
ACRV1

acrosomal vesicle protein 1

chr7_-_107443652 0.612 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3


solute carrier family 26 (anion exchanger), member 3


chr15_-_34628951 0.609 ENST00000397707.2
ENST00000560611.1
SLC12A6

solute carrier family 12 (potassium/chloride transporter), member 6

chr1_-_167487808 0.605 ENST00000392122.3
CD247
CD247 molecule
chr13_+_31309645 0.604 ENST00000380490.3
ALOX5AP
arachidonate 5-lipoxygenase-activating protein
chr15_+_42066740 0.603 ENST00000514566.1
MAPKBP1
mitogen-activated protein kinase binding protein 1
chr8_+_70404996 0.590 ENST00000402687.4
ENST00000419716.3
SULF1

sulfatase 1

chr2_+_201994569 0.586 ENST00000457277.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr12_+_53662110 0.579 ENST00000552462.1
ESPL1
extra spindle pole bodies homolog 1 (S. cerevisiae)
chr14_-_85996332 0.579 ENST00000380722.1
RP11-497E19.1
RP11-497E19.1
chr18_+_21452804 0.574 ENST00000269217.6
LAMA3
laminin, alpha 3
chr19_-_51522955 0.573 ENST00000358789.3
KLK10
kallikrein-related peptidase 10
chr15_-_74501360 0.573 ENST00000323940.5
STRA6
stimulated by retinoic acid 6
chr12_-_10022735 0.550 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr2_+_201994208 0.544 ENST00000440180.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chrX_+_48380205 0.544 ENST00000446158.1
ENST00000414061.1
EBP

emopamil binding protein (sterol isomerase)

chr4_-_52883786 0.543 ENST00000343457.3
LRRC66
leucine rich repeat containing 66
chr6_+_167704838 0.539 ENST00000366829.2
UNC93A
unc-93 homolog A (C. elegans)
chr7_-_23510086 0.537 ENST00000258729.3
IGF2BP3
insulin-like growth factor 2 mRNA binding protein 3
chr10_+_52152766 0.536 ENST00000596442.1
AC069547.2
Uncharacterized protein
chr1_+_209859510 0.534 ENST00000367028.2
ENST00000261465.1
HSD11B1

hydroxysteroid (11-beta) dehydrogenase 1

chr7_+_139528952 0.533 ENST00000416849.2
ENST00000436047.2
ENST00000414508.2
ENST00000448866.1
TBXAS1



thromboxane A synthase 1 (platelet)



chr20_-_54967187 0.530 ENST00000422322.1
ENST00000371356.2
ENST00000451915.1
ENST00000347343.2
ENST00000395911.1
ENST00000395907.1
ENST00000441357.1
ENST00000456249.1
ENST00000420474.1
ENST00000395909.4
ENST00000395914.1
ENST00000312783.6
ENST00000395915.3
ENST00000395913.3
AURKA













aurora kinase A













chr2_+_28618532 0.529 ENST00000545753.1
FOSL2
FOS-like antigen 2
chr2_+_197504278 0.529 ENST00000272831.7
ENST00000389175.4
ENST00000472405.2
ENST00000423093.2
CCDC150



coiled-coil domain containing 150



chr17_+_4853442 0.525 ENST00000522301.1
ENO3
enolase 3 (beta, muscle)
chr10_+_5566916 0.525 ENST00000315238.1
CALML3
calmodulin-like 3
chr2_-_231825668 0.520 ENST00000392039.2
GPR55
G protein-coupled receptor 55
chr1_+_192127578 0.518 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr17_-_64225508 0.514 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr7_+_155090271 0.512 ENST00000476756.1
INSIG1
insulin induced gene 1
chr6_+_31691121 0.510 ENST00000480039.1
ENST00000375810.4
ENST00000375805.2
ENST00000375809.3
ENST00000375804.2
ENST00000375814.3
ENST00000375806.2
C6orf25






chromosome 6 open reading frame 25






chr6_-_35765088 0.508 ENST00000259938.2
CLPS
colipase, pancreatic
chrX_-_65253506 0.503 ENST00000427538.1
VSIG4
V-set and immunoglobulin domain containing 4
chr1_-_159880159 0.502 ENST00000599780.1
AL590560.1
HCG1995379; Uncharacterized protein
chr17_+_46537697 0.501 ENST00000579972.1
RP11-433M22.2
RP11-433M22.2
chr19_-_36822595 0.496 ENST00000585356.1
ENST00000438368.2
ENST00000590622.1
LINC00665


long intergenic non-protein coding RNA 665


chr10_+_118305435 0.494 ENST00000369221.2
PNLIP
pancreatic lipase
chr11_+_128563652 0.488 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr19_-_51568324 0.485 ENST00000595547.1
ENST00000335422.3
ENST00000595793.1
ENST00000596955.1
KLK13



kallikrein-related peptidase 13



chr16_+_202686 0.484 ENST00000252951.2
HBZ
hemoglobin, zeta
chr6_+_167704798 0.482 ENST00000230256.3
UNC93A
unc-93 homolog A (C. elegans)
chr1_+_115572415 0.481 ENST00000256592.1
TSHB
thyroid stimulating hormone, beta
chr4_-_143227088 0.477 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr10_-_71993176 0.475 ENST00000373232.3
PPA1
pyrophosphatase (inorganic) 1
chr19_-_41934635 0.475 ENST00000321702.2
B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr14_-_50559361 0.463 ENST00000305273.1
C14orf183
chromosome 14 open reading frame 183
chr5_+_159848854 0.461 ENST00000517480.1
ENST00000520452.1
ENST00000393964.1
PTTG1


pituitary tumor-transforming 1


chr2_-_106054952 0.461 ENST00000336660.5
ENST00000393352.3
ENST00000607522.1
FHL2


four and a half LIM domains 2


chr1_-_225616515 0.458 ENST00000338179.2
ENST00000425080.1
LBR

lamin B receptor

chr14_-_81893734 0.457 ENST00000555447.1
STON2
stonin 2
chr3_-_150996239 0.451 ENST00000309170.3
P2RY14
purinergic receptor P2Y, G-protein coupled, 14
chrX_-_55057403 0.445 ENST00000396198.3
ENST00000335854.4
ENST00000455688.1
ENST00000330807.5
ALAS2



aminolevulinate, delta-, synthase 2



chr7_+_153584166 0.445 ENST00000404039.1
DPP6
dipeptidyl-peptidase 6
chr1_-_175162048 0.444 ENST00000444639.1
KIAA0040
KIAA0040
chr15_+_67418047 0.442 ENST00000540846.2
SMAD3
SMAD family member 3
chr7_+_123295861 0.440 ENST00000458573.2
ENST00000456238.2
LMOD2

leiomodin 2 (cardiac)

chr15_+_74165945 0.437 ENST00000535547.2
ENST00000300504.2
ENST00000562056.1
TBC1D21


TBC1 domain family, member 21


chr20_+_34713312 0.434 ENST00000373946.3
EPB41L1
erythrocyte membrane protein band 4.1-like 1
chr2_+_210517895 0.431 ENST00000447185.1
MAP2
microtubule-associated protein 2
chr22_-_29784519 0.429 ENST00000357586.2
ENST00000356015.2
ENST00000432560.2
ENST00000317368.7
AP1B1



adaptor-related protein complex 1, beta 1 subunit



chr1_-_155270770 0.429 ENST00000392414.3
PKLR
pyruvate kinase, liver and RBC
chr12_+_75874984 0.428 ENST00000550491.1
GLIPR1
GLI pathogenesis-related 1
chr1_+_35247859 0.428 ENST00000373362.3
GJB3
gap junction protein, beta 3, 31kDa
chr8_-_133123406 0.427 ENST00000434736.2
HHLA1
HERV-H LTR-associating 1
chr1_-_25747283 0.424 ENST00000346452.4
ENST00000340849.4
ENST00000349438.4
ENST00000294413.7
ENST00000413854.1
ENST00000455194.1
ENST00000243186.6
ENST00000425135.1
RHCE







Rh blood group, CcEe antigens







chrX_-_24665353 0.422 ENST00000379144.2
PCYT1B
phosphate cytidylyltransferase 1, choline, beta
chr17_+_37824217 0.420 ENST00000394246.1
PNMT
phenylethanolamine N-methyltransferase
chr1_+_150954493 0.420 ENST00000368947.4
ANXA9
annexin A9
chr2_-_8464760 0.418 ENST00000430192.1
LINC00299
long intergenic non-protein coding RNA 299
chr12_-_10324716 0.418 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1



oxidized low density lipoprotein (lectin-like) receptor 1



chr12_-_68647281 0.418 ENST00000328087.4
ENST00000538666.1
IL22

interleukin 22

chr14_-_24584138 0.417 ENST00000558280.1
ENST00000561028.1
NRL

neural retina leucine zipper

chr20_+_42984330 0.414 ENST00000316673.4
ENST00000609795.1
ENST00000457232.1
ENST00000609262.1
HNF4A



hepatocyte nuclear factor 4, alpha



chr19_-_51523275 0.414 ENST00000309958.3
KLK10
kallikrein-related peptidase 10
chr13_+_32313658 0.411 ENST00000380314.1
ENST00000298386.2
RXFP2

relaxin/insulin-like family peptide receptor 2

chr2_+_220436917 0.410 ENST00000243786.2
INHA
inhibin, alpha
chr19_-_51017881 0.408 ENST00000601207.1
ENST00000598657.1
ENST00000376916.3
ASPDH


aspartate dehydrogenase domain containing


chr1_-_226187013 0.406 ENST00000272091.7
SDE2
SDE2 telomere maintenance homolog (S. pombe)
chr8_+_42873548 0.405 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr1_+_50574585 0.404 ENST00000371824.1
ENST00000371823.4
ELAVL4

ELAV like neuron-specific RNA binding protein 4

chr4_-_65275162 0.401 ENST00000381210.3
ENST00000507440.1
TECRL

trans-2,3-enoyl-CoA reductase-like

chr8_+_27629459 0.400 ENST00000523566.1
ESCO2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr19_+_6739662 0.398 ENST00000313285.8
ENST00000313244.9
ENST00000596758.1
TRIP10


thyroid hormone receptor interactor 10


chr3_-_187009646 0.395 ENST00000296280.6
ENST00000392470.2
ENST00000169293.6
ENST00000439271.1
ENST00000392472.2
ENST00000392475.2
MASP1





mannan-binding lectin serine peptidase 1 (C4/C2 activating component of Ra-reactive factor)





chr3_+_101818088 0.393 ENST00000491959.1
ZPLD1
zona pellucida-like domain containing 1
chr3_-_194188956 0.393 ENST00000256031.4
ENST00000446356.1
ATP13A3

ATPase type 13A3

chr15_+_42066632 0.389 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
MAPKBP1



mitogen-activated protein kinase binding protein 1



chr2_+_201994042 0.379 ENST00000417748.1
CFLAR
CASP8 and FADD-like apoptosis regulator
chr8_-_143961236 0.378 ENST00000377675.3
ENST00000517471.1
ENST00000292427.4
CYP11B1


cytochrome P450, family 11, subfamily B, polypeptide 1


chr10_-_25241499 0.378 ENST00000376378.1
ENST00000376376.3
ENST00000320152.6
PRTFDC1


phosphoribosyl transferase domain containing 1


chr2_+_90077680 0.373 ENST00000390270.2
IGKV3D-20
immunoglobulin kappa variable 3D-20
chr11_-_19082216 0.373 ENST00000329773.2
MRGPRX2
MAS-related GPR, member X2
chr14_-_72458326 0.372 ENST00000542853.1
AC005477.1
AC005477.1
chr8_-_15095832 0.371 ENST00000382080.1
SGCZ
sarcoglycan, zeta
chr21_+_39628852 0.371 ENST00000398938.2
KCNJ15
potassium inwardly-rectifying channel, subfamily J, member 15
chr1_-_214638146 0.371 ENST00000543945.1
PTPN14
protein tyrosine phosphatase, non-receptor type 14
chr20_+_43935474 0.368 ENST00000372743.1
ENST00000372741.3
ENST00000343694.3
RBPJL


recombination signal binding protein for immunoglobulin kappa J region-like


chr14_-_65409502 0.368 ENST00000389614.5
GPX2
glutathione peroxidase 2 (gastrointestinal)
chr2_-_14541060 0.367 ENST00000418420.1
ENST00000417751.1
LINC00276

long intergenic non-protein coding RNA 276

chr12_+_32655048 0.364 ENST00000427716.2
ENST00000266482.3
FGD4

FYVE, RhoGEF and PH domain containing 4

chr9_-_127269661 0.364 ENST00000373588.4
NR5A1
nuclear receptor subfamily 5, group A, member 1
chr5_-_76788317 0.361 ENST00000296679.4
WDR41
WD repeat domain 41
chr1_+_25599018 0.360 ENST00000417538.2
ENST00000357542.4
ENST00000568195.1
ENST00000342055.5
ENST00000423810.2
RHD




Rh blood group, D antigen




chr5_-_135290705 0.359 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.5 GO:0002784 regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786)
0.6 3.5 GO:0038172 interleukin-33-mediated signaling pathway(GO:0038172)
0.5 1.6 GO:0046521 sphingoid catabolic process(GO:0046521)
0.4 1.3 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)
0.3 1.0 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.3 0.9 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
0.3 1.5 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.3 1.2 GO:0045875 negative regulation of sister chromatid cohesion(GO:0045875)
0.3 2.9 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.2 1.0 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.2 1.4 GO:0051012 microtubule sliding(GO:0051012)
0.2 0.9 GO:0009822 alkaloid catabolic process(GO:0009822)
0.2 0.6 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781)
0.2 2.0 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 0.7 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.2 0.7 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 5.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.2 0.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.2 0.5 GO:0007057 spindle assembly involved in female meiosis I(GO:0007057) positive regulation of oocyte maturation(GO:1900195)
0.2 0.5 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 0.7 GO:0042418 epinephrine biosynthetic process(GO:0042418)
0.2 1.7 GO:0051597 response to methylmercury(GO:0051597)
0.2 0.8 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.2 0.8 GO:0061767 negative regulation of lung blood pressure(GO:0061767)
0.1 0.6 GO:0003366 cell-matrix adhesion involved in ameboidal cell migration(GO:0003366)
0.1 0.6 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.1 0.1 GO:0002652 regulation of tolerance induction dependent upon immune response(GO:0002652)
0.1 0.9 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.1 0.9 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.1 0.4 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.4 GO:0006742 NADP catabolic process(GO:0006742) pyridine nucleotide catabolic process(GO:0019364)
0.1 0.4 GO:0010949 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
0.1 0.7 GO:0061143 alveolar primary septum development(GO:0061143)
0.1 0.4 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 0.7 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 3.0 GO:0071481 cellular response to X-ray(GO:0071481)
0.1 0.5 GO:0071344 diphosphate metabolic process(GO:0071344)
0.1 0.5 GO:0030311 poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 0.4 GO:1901350 cell-cell signaling involved in cell-cell junction organization(GO:1901350)
0.1 0.3 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.1 0.3 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.3 GO:0003218 cardiac left ventricle formation(GO:0003218)
0.1 0.5 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.1 0.4 GO:0045872 positive regulation of rhodopsin gene expression(GO:0045872)
0.1 0.7 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.1 0.3 GO:0044179 cytolysis by symbiont of host cells(GO:0001897) hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331)
0.1 0.3 GO:0018874 benzoate metabolic process(GO:0018874)
0.1 1.3 GO:0019532 oxalate transport(GO:0019532)
0.1 0.6 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.1 0.2 GO:0016103 diterpenoid catabolic process(GO:0016103) retinoic acid catabolic process(GO:0034653)
0.1 0.5 GO:0055014 atrial cardiac muscle cell differentiation(GO:0055011) atrial cardiac muscle cell development(GO:0055014)
0.1 0.7 GO:0072205 metanephric collecting duct development(GO:0072205)
0.1 0.4 GO:0007538 primary sex determination(GO:0007538)
0.1 0.4 GO:0036269 swimming behavior(GO:0036269)
0.1 0.9 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.1 0.9 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 0.2 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.1 0.2 GO:2000015 regulation of determination of dorsal identity(GO:2000015)
0.1 0.3 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.1 0.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.9 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 1.1 GO:0043320 natural killer cell degranulation(GO:0043320)
0.1 0.3 GO:0007499 ectoderm and mesoderm interaction(GO:0007499)
0.1 1.5 GO:0044241 lipid digestion(GO:0044241)
0.1 1.1 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.1 0.3 GO:0050928 negative regulation of positive chemotaxis(GO:0050928)
0.1 0.2 GO:0040010 positive regulation of growth rate(GO:0040010) regulation of gastric mucosal blood circulation(GO:1904344) positive regulation of gastric mucosal blood circulation(GO:1904346) gastric mucosal blood circulation(GO:1990768)
0.1 0.2 GO:1903487 regulation of lactation(GO:1903487)
0.1 0.2 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.6 GO:2001300 lipoxin metabolic process(GO:2001300)
0.1 9.0 GO:0070268 cornification(GO:0070268)
0.1 0.4 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.2 GO:0001694 histamine biosynthetic process(GO:0001694)
0.1 0.4 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.1 1.0 GO:0023041 neuronal signal transduction(GO:0023041) negative regulation of axon regeneration(GO:0048681)
0.1 0.8 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.2 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.2 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.1 0.8 GO:0046325 negative regulation of glucose import(GO:0046325)
0.1 0.2 GO:0045226 extracellular polysaccharide biosynthetic process(GO:0045226) extracellular polysaccharide metabolic process(GO:0046379) renal water absorption(GO:0070295)
0.1 2.5 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.6 GO:0034378 chylomicron assembly(GO:0034378)
0.1 0.2 GO:0008050 female courtship behavior(GO:0008050)
0.1 0.6 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.1 0.3 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.2 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.2 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.3 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.3 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.1 0.2 GO:0031100 organ regeneration(GO:0031100)
0.1 0.2 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.2 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.9 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.2 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 0.4 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:1990523 bone regeneration(GO:1990523)
0.0 0.1 GO:0002027 regulation of heart rate(GO:0002027)
0.0 0.9 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0044340 canonical Wnt signaling pathway involved in regulation of cell proliferation(GO:0044340)
0.0 0.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:1901379 regulation of potassium ion transmembrane transport(GO:1901379)
0.0 0.4 GO:0070197 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.7 GO:1904778 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.1 GO:0007518 myoblast fate determination(GO:0007518)
0.0 0.1 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.2 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.0 0.4 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.0 0.6 GO:0032836 glomerular basement membrane development(GO:0032836)
0.0 2.1 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.4 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.2 GO:0006196 AMP catabolic process(GO:0006196)
0.0 0.7 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.5 GO:0038171 cannabinoid signaling pathway(GO:0038171)
0.0 0.4 GO:0032341 aldosterone metabolic process(GO:0032341) aldosterone biosynthetic process(GO:0032342)
0.0 0.3 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.2 GO:0071400 cellular response to oleic acid(GO:0071400)
0.0 0.2 GO:0098707 ferrous iron import(GO:0070627) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.9 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 3.5 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.3 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.1 GO:0003285 septum secundum development(GO:0003285)
0.0 0.3 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.2 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.2 GO:0051342 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.2 GO:0051933 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.0 0.7 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0051873 killing by host of symbiont cells(GO:0051873)
0.0 0.4 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 2.6 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.3 GO:0055091 phospholipid homeostasis(GO:0055091) positive regulation of cholesterol homeostasis(GO:2000189)
0.0 1.5 GO:0046627 negative regulation of insulin receptor signaling pathway(GO:0046627) negative regulation of cellular response to insulin stimulus(GO:1900077)
0.0 0.1 GO:1901895 regulation of the force of heart contraction by cardiac conduction(GO:0086092) regulation of calcium ion binding(GO:1901876) negative regulation of calcium ion binding(GO:1901877) negative regulation of calcium-transporting ATPase activity(GO:1901895) regulation of calcium ion import into sarcoplasmic reticulum(GO:1902080) negative regulation of calcium ion import into sarcoplasmic reticulum(GO:1902081)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.2 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.9 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.3 GO:0060215 primitive hemopoiesis(GO:0060215)
0.0 0.8 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 1.4 GO:0033046 negative regulation of sister chromatid segregation(GO:0033046) negative regulation of mitotic sister chromatid segregation(GO:0033048) negative regulation of mitotic sister chromatid separation(GO:2000816)
0.0 0.2 GO:0019556 histidine catabolic process to glutamate and formamide(GO:0019556) histidine catabolic process to glutamate and formate(GO:0019557) formamide metabolic process(GO:0043606)
0.0 0.2 GO:0033384 geranyl diphosphate metabolic process(GO:0033383) geranyl diphosphate biosynthetic process(GO:0033384) farnesyl diphosphate biosynthetic process(GO:0045337)
0.0 1.2 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.5 GO:0032703 negative regulation of interleukin-2 production(GO:0032703)
0.0 0.7 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.4 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.2 GO:0006657 CDP-choline pathway(GO:0006657)
0.0 0.3 GO:0034312 diol biosynthetic process(GO:0034312) sphingosine biosynthetic process(GO:0046512)
0.0 0.5 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.3 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.3 GO:0070970 interleukin-2 secretion(GO:0070970)
0.0 0.3 GO:0010629 negative regulation of gene expression(GO:0010629)
0.0 0.4 GO:0098609 cell-cell adhesion(GO:0098609)
0.0 0.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0038129 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) ERBB3 signaling pathway(GO:0038129)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.0 0.3 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873)
0.0 0.2 GO:0036444 calcium ion transmembrane import into mitochondrion(GO:0036444)
0.0 0.1 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.1 GO:2001240 negative regulation of signal transduction in absence of ligand(GO:1901099) regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001239) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.0 0.3 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.0 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.1 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.0 0.4 GO:0001946 lymphangiogenesis(GO:0001946)
0.0 0.3 GO:0043383 negative T cell selection(GO:0043383)
0.0 0.1 GO:2000360 negative regulation of binding of sperm to zona pellucida(GO:2000360)
0.0 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.2 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.0 0.2 GO:0030091 protein repair(GO:0030091)
0.0 0.7 GO:1900027 regulation of ruffle assembly(GO:1900027)
0.0 0.2 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.2 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.0 0.1 GO:1900005 positive regulation of serine-type endopeptidase activity(GO:1900005) negative regulation of sperm motility(GO:1901318) positive regulation of serine-type peptidase activity(GO:1902573)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.1 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.4 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.3 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0033632 regulation of cell-cell adhesion mediated by integrin(GO:0033632)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0020027 hemoglobin metabolic process(GO:0020027)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.1 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.1 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.0 GO:0097156 fasciculation of motor neuron axon(GO:0097156)
0.0 0.2 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.5 GO:0006825 copper ion transport(GO:0006825)
0.0 0.7 GO:0045687 positive regulation of glial cell differentiation(GO:0045687)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 1.4 GO:0001570 vasculogenesis(GO:0001570)
0.0 0.5 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:1902161 transepithelial water transport(GO:0035377) positive regulation of cyclic nucleotide-gated ion channel activity(GO:1902161)
0.0 0.2 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.3 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.4 GO:0001556 oocyte maturation(GO:0001556)
0.0 0.1 GO:0060737 prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737)
0.0 0.5 GO:0043403 skeletal muscle tissue regeneration(GO:0043403)
0.0 0.2 GO:0050884 neuromuscular process controlling posture(GO:0050884)
0.0 0.7 GO:0006739 NADP metabolic process(GO:0006739)
0.0 1.2 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.1 GO:0060613 fat pad development(GO:0060613)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.2 GO:0006054 N-acetylneuraminate metabolic process(GO:0006054)
0.0 0.4 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.8 GO:0007566 embryo implantation(GO:0007566)
0.0 0.2 GO:0001765 membrane raft assembly(GO:0001765)
0.0 0.2 GO:0098828 positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828)
0.0 2.8 GO:0007173 epidermal growth factor receptor signaling pathway(GO:0007173)
0.0 0.4 GO:0046716 muscle cell cellular homeostasis(GO:0046716)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.1 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.0 0.1 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.2 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0002316 follicular B cell differentiation(GO:0002316)
0.0 0.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.5 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.2 GO:0035641 locomotory exploration behavior(GO:0035641)
0.0 0.1 GO:0002643 regulation of tolerance induction(GO:0002643)
0.0 0.1 GO:0006704 glucocorticoid biosynthetic process(GO:0006704)
0.0 0.9 GO:0006968 cellular defense response(GO:0006968)
0.0 0.0 GO:0014738 regulation of muscle hyperplasia(GO:0014738)
0.0 0.4 GO:0001501 skeletal system development(GO:0001501)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.0 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.2 GO:1901841 regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0 0.2 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.2 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.1 GO:0009957 epidermal cell fate specification(GO:0009957)
0.0 0.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:1903027 regulation of complement activation, classical pathway(GO:0030450) negative regulation of complement activation, classical pathway(GO:0045959) regulation of opsonization(GO:1903027)
0.0 0.3 GO:0097421 liver regeneration(GO:0097421)
0.0 0.3 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.5 GO:0097209 epidermal lamellar body(GO:0097209)
0.5 3.0 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.2 1.0 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.6 GO:0034669 integrin alpha4-beta7 complex(GO:0034669)
0.1 0.6 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.7 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.4 GO:0043511 inhibin complex(GO:0043511) inhibin A complex(GO:0043512)
0.1 0.5 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.5 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 1.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.6 GO:0070876 SOSS complex(GO:0070876)
0.1 0.3 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005) other organism cytoplasm(GO:0097679)
0.1 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.9 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.8 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.8 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 2.0 GO:0031265 CD95 death-inducing signaling complex(GO:0031265) ripoptosome(GO:0097342)
0.1 1.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 5.8 GO:0001533 cornified envelope(GO:0001533)
0.1 0.6 GO:0005587 collagen type IV trimer(GO:0005587)
0.1 0.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.4 GO:0070695 FHF complex(GO:0070695)
0.1 0.9 GO:0008091 spectrin(GO:0008091)
0.1 1.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.2 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 1.0 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0038038 G-protein coupled receptor homodimeric complex(GO:0038038)
0.0 1.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.6 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.9 GO:0036020 endolysosome membrane(GO:0036020)
0.0 3.4 GO:1904724 tertiary granule lumen(GO:1904724)
0.0 0.3 GO:1990393 Cul7-RING ubiquitin ligase complex(GO:0031467) 3M complex(GO:1990393)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.0 0.3 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.8 GO:0042627 chylomicron(GO:0042627)
0.0 0.6 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.1 GO:0036025 protein C inhibitor-TMPRSS7 complex(GO:0036024) protein C inhibitor-TMPRSS11E complex(GO:0036025) protein C inhibitor-PLAT complex(GO:0036026) protein C inhibitor-PLAU complex(GO:0036027) protein C inhibitor-thrombin complex(GO:0036028) protein C inhibitor-KLK3 complex(GO:0036029) protein C inhibitor-plasma kallikrein complex(GO:0036030) serine protease inhibitor complex(GO:0097180) protein C inhibitor-coagulation factor V complex(GO:0097181) protein C inhibitor-coagulation factor Xa complex(GO:0097182) protein C inhibitor-coagulation factor XI complex(GO:0097183)
0.0 2.6 GO:0072686 mitotic spindle(GO:0072686)
0.0 1.0 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.7 GO:0031105 septin complex(GO:0031105)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.4 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.8 GO:0005921 gap junction(GO:0005921)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.3 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 0.4 GO:0030426 growth cone(GO:0030426)
0.0 0.4 GO:0031672 A band(GO:0031672)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.3 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.0 GO:0030895 apolipoprotein B mRNA editing enzyme complex(GO:0030895)
0.0 1.7 GO:0005604 basement membrane(GO:0005604)
0.0 0.3 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 1.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.4 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0097449 astrocyte projection(GO:0097449)
0.0 2.5 GO:0043197 dendritic spine(GO:0043197)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0045179 apical cortex(GO:0045179)
0.0 1.2 GO:0070821 tertiary granule membrane(GO:0070821)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 3.3 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0002113 interleukin-33 binding(GO:0002113)
0.6 3.4 GO:0042015 interleukin-20 binding(GO:0042015)
0.3 1.0 GO:0038131 neuregulin receptor activity(GO:0038131)
0.3 0.9 GO:0045518 interleukin-22 receptor binding(GO:0045518)
0.3 1.6 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.3 0.8 GO:0050613 delta14-sterol reductase activity(GO:0050613)
0.2 0.7 GO:0004603 phenylethanolamine N-methyltransferase activity(GO:0004603)
0.2 1.3 GO:0030197 extracellular matrix constituent, lubricant activity(GO:0030197)
0.2 0.6 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.2 1.0 GO:0031708 endothelin B receptor binding(GO:0031708)
0.2 0.6 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.2 0.7 GO:0004743 pyruvate kinase activity(GO:0004743)
0.2 2.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.2 0.5 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 0.5 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.2 0.9 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.2 0.8 GO:0031962 mineralocorticoid receptor binding(GO:0031962)
0.2 1.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.4 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.1 0.7 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.4 GO:0004507 steroid 11-beta-monooxygenase activity(GO:0004507) corticosterone 18-monooxygenase activity(GO:0047783)
0.1 0.7 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 1.3 GO:0003960 NADPH:quinone reductase activity(GO:0003960)
0.1 1.5 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 0.8 GO:0004882 androgen receptor activity(GO:0004882)
0.1 0.5 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.7 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.1 1.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.5 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.8 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.6 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.1 0.5 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.6 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.1 0.5 GO:0045029 UDP-activated nucleotide receptor activity(GO:0045029)
0.1 0.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.2 GO:0045499 chemorepellent activity(GO:0045499)
0.1 2.1 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 2.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.7 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.1 0.5 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.6 GO:0086056 voltage-gated calcium channel activity involved in AV node cell action potential(GO:0086056)
0.1 0.2 GO:0000035 acyl binding(GO:0000035)
0.1 0.7 GO:0042731 PH domain binding(GO:0042731)
0.1 0.2 GO:0031768 ghrelin receptor binding(GO:0031768)
0.1 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 0.7 GO:0031419 cobalamin binding(GO:0031419)
0.1 2.0 GO:0097200 death receptor binding(GO:0005123) cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.4 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 1.1 GO:0004896 cytokine receptor activity(GO:0004896)
0.1 0.2 GO:0003943 N-acetylgalactosamine-4-sulfatase activity(GO:0003943)
0.1 0.5 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.3 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.2 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.4 GO:0034711 inhibin binding(GO:0034711)
0.1 0.4 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.9 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 1.6 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.2 GO:0004998 transferrin receptor activity(GO:0004998)
0.0 0.9 GO:0033612 receptor serine/threonine kinase binding(GO:0033612)
0.0 0.2 GO:0010348 lithium:proton antiporter activity(GO:0010348)
0.0 0.2 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.0 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.2 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.1 GO:0005497 androgen binding(GO:0005497)
0.0 0.2 GO:0004105 choline-phosphate cytidylyltransferase activity(GO:0004105)
0.0 0.3 GO:0030172 troponin C binding(GO:0030172)
0.0 0.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 11.9 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.7 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.4 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.3 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 2.9 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0051990 isocitrate dehydrogenase (NADP+) activity(GO:0004450) (R)-2-hydroxyglutarate dehydrogenase activity(GO:0051990)
0.0 0.2 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.2 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.3 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 1.5 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.0 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.0 0.1 GO:0004995 tachykinin receptor activity(GO:0004995)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208)
0.0 0.2 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.0 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.4 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.1 GO:0030109 HLA-B specific inhibitory MHC class I receptor activity(GO:0030109)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0019864 IgG binding(GO:0019864)
0.0 0.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 1.6 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.4 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.3 GO:0043225 anion transmembrane-transporting ATPase activity(GO:0043225)
0.0 0.1 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.5 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0001596 angiotensin type I receptor activity(GO:0001596)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.4 GO:0031432 titin binding(GO:0031432)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 2.9 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.7 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.4 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 1.8 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.4 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.5 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.4 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.4 GO:0042923 neuropeptide binding(GO:0042923)
0.0 1.4 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.1 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 14.1 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.1 GO:0030250 cyclase activator activity(GO:0010853) guanylate cyclase activator activity(GO:0030250)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.2 GO:0016615 malate dehydrogenase activity(GO:0016615)
0.0 0.3 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.0 GO:0015265 urea transmembrane transporter activity(GO:0015204) urea channel activity(GO:0015265)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0016638 oxidoreductase activity, acting on the CH-NH2 group of donors(GO:0016638)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.1 GO:0032190 acrosin binding(GO:0032190)
0.0 0.4 GO:0015464 acetylcholine receptor activity(GO:0015464)
0.0 0.4 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 1.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.0 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.3 GO:0001871 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.2 GO:0019841 retinol binding(GO:0019841)
0.0 0.1 GO:0005119 smoothened binding(GO:0005119)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.6 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.2 GO:0051183 vitamin transporter activity(GO:0051183)
0.0 0.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 SA_FAS_SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 3.1 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.1 1.6 PID_S1P_META_PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 4.9 PID_TCR_PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.8 PID_INTEGRIN4_PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.9 PID_INSULIN_PATHWAY Insulin Pathway
0.0 1.9 PID_INTEGRIN2_PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID_IL6_7_PATHWAY IL6-mediated signaling events
0.0 3.1 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.0 PID_ALK1_PATHWAY ALK1 signaling events
0.0 0.2 ST_JAK_STAT_PATHWAY Jak-STAT Pathway
0.0 1.4 PID_FCER1_PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.9 PID_INTEGRIN_A9B1_PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.3 PID_FAK_PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.2 SA_B_CELL_RECEPTOR_COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 1.6 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 1.2 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity
0.0 1.2 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID_NEPHRIN_NEPH1_PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.2 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.6 PID_INTEGRIN3_PATHWAY Beta3 integrin cell surface interactions
0.0 0.7 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 1.0 PID_HES_HEY_PATHWAY Notch-mediated HES/HEY network
0.0 0.2 PID_KIT_PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.8 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 5.2 NABA_ECM_REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID_AR_NONGENOMIC_PATHWAY Nongenotropic Androgen signaling
0.0 0.5 SIG_PIP3_SIGNALING_IN_CARDIAC_MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.1 ST_PAC1_RECEPTOR_PATHWAY PAC1 Receptor Pathway
0.0 0.2 ST_INTERLEUKIN_4_PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.3 PID_ANGIOPOIETIN_RECEPTOR_PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.4 SA_MMP_CYTOKINE_CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.5 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 ST_WNT_BETA_CATENIN_PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID_PI3K_PLC_TRK_PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 1.0 PID_P75_NTR_PATHWAY p75(NTR)-mediated signaling
0.0 0.4 PID_PTP1B_PATHWAY Signaling events mediated by PTP1B
0.0 5.0 NABA_SECRETED_FACTORS Genes encoding secreted soluble factors
0.0 0.2 ST_T_CELL_SIGNAL_TRANSDUCTION T Cell Signal Transduction

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 REACTOME_ZINC_TRANSPORTERS Genes involved in Zinc transporters
0.1 0.7 REACTOME_METAL_ION_SLC_TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 2.0 REACTOME_EXTRINSIC_PATHWAY_FOR_APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 2.5 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 3.0 REACTOME_THE_ROLE_OF_NEF_IN_HIV1_REPLICATION_AND_DISEASE_PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.1 1.3 REACTOME_TIE2_SIGNALING Genes involved in Tie2 Signaling
0.0 0.8 REACTOME_SIGNAL_ATTENUATION Genes involved in Signal attenuation
0.0 1.5 REACTOME_CHOLESTEROL_BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 3.1 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.7 REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 1.6 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.7 REACTOME_SYNTHESIS_OF_PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 1.7 REACTOME_GLUCOSE_TRANSPORT Genes involved in Glucose transport
0.0 0.5 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 3.0 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.6 REACTOME_INHIBITION_OF_INSULIN_SECRETION_BY_ADRENALINE_NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 1.3 REACTOME_GLYCOLYSIS Genes involved in Glycolysis
0.0 0.5 REACTOME_CELL_SURFACE_INTERACTIONS_AT_THE_VASCULAR_WALL Genes involved in Cell surface interactions at the vascular wall
0.0 2.0 REACTOME_LIPID_DIGESTION_MOBILIZATION_AND_TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 0.5 REACTOME_SYNTHESIS_OF_PIPS_AT_THE_EARLY_ENDOSOME_MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 1.0 REACTOME_DOWNREGULATION_OF_TGF_BETA_RECEPTOR_SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.6 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.6 REACTOME_NRAGE_SIGNALS_DEATH_THROUGH_JNK Genes involved in NRAGE signals death through JNK
0.0 0.7 REACTOME_G_ALPHA1213_SIGNALLING_EVENTS Genes involved in G alpha (12/13) signalling events
0.0 0.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME_GAP_JUNCTION_ASSEMBLY Genes involved in Gap junction assembly
0.0 0.7 REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME_HYALURONAN_METABOLISM Genes involved in Hyaluronan metabolism
0.0 1.8 REACTOME_APC_C_CDH1_MEDIATED_DEGRADATION_OF_CDC20_AND_OTHER_APC_C_CDH1_TARGETED_PROTEINS_IN_LATE_MITOSIS_EARLY_G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.0 1.5 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME_G_PROTEIN_ACTIVATION Genes involved in G-protein activation
0.0 0.2 REACTOME_PLATELET_ADHESION_TO_EXPOSED_COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.5 REACTOME_CYTOSOLIC_TRNA_AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.3 REACTOME_ACTIVATION_OF_NF_KAPPAB_IN_B_CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.2 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.3 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.1 REACTOME_ACTIVATION_OF_CHAPERONE_GENES_BY_ATF6_ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 2.1 REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS Genes involved in G alpha (q) signalling events