Motif ID: GAUUGUC
Z-value: 0.789
Mature miRNA associated with seed GAUUGUC:
Name | miRBase Accession |
---|---|
hsa-miR-219a-5p | MIMAT0000276 |
hsa-miR-4782-3p | MIMAT0019945 |
hsa-miR-6766-3p | MIMAT0027433 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.9 | 3.5 | GO:0033634 | positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) |
0.8 | 3.9 | GO:0002415 | immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415) |
0.6 | 1.8 | GO:0021524 | visceral motor neuron differentiation(GO:0021524) peripheral nervous system neuron axonogenesis(GO:0048936) cardiac cell fate determination(GO:0060913) |
0.5 | 1.5 | GO:0090076 | relaxation of skeletal muscle(GO:0090076) |
0.4 | 1.2 | GO:1901860 | positive regulation of mitochondrial DNA metabolic process(GO:1901860) |
0.3 | 0.8 | GO:0045925 | positive regulation of female receptivity(GO:0045925) |
0.2 | 1.4 | GO:0007352 | zygotic specification of dorsal/ventral axis(GO:0007352) |
0.2 | 2.6 | GO:1903025 | regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025) |
0.2 | 1.0 | GO:0014005 | microglia differentiation(GO:0014004) microglia development(GO:0014005) |
0.2 | 0.5 | GO:0061300 | cerebellum vasculature development(GO:0061300) |
0.1 | 0.4 | GO:0097156 | fasciculation of motor neuron axon(GO:0097156) |
0.1 | 1.3 | GO:0030643 | cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502) |
0.1 | 0.4 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) |
0.1 | 0.2 | GO:0030505 | inorganic diphosphate transport(GO:0030505) |
0.1 | 0.6 | GO:0010961 | cellular magnesium ion homeostasis(GO:0010961) |
0.1 | 1.6 | GO:0060907 | positive regulation of macrophage cytokine production(GO:0060907) |
0.1 | 0.3 | GO:0070253 | somatostatin secretion(GO:0070253) |
0.1 | 0.5 | GO:0072719 | cellular response to cisplatin(GO:0072719) |
0.1 | 0.7 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
0.1 | 0.2 | GO:2000705 | dense core granule biogenesis(GO:0061110) regulation of dense core granule biogenesis(GO:2000705) |
0.1 | 0.4 | GO:0001555 | oocyte growth(GO:0001555) |
0.1 | 0.2 | GO:0021823 | cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836) |
0.1 | 1.0 | GO:1900038 | negative regulation of cellular response to hypoxia(GO:1900038) |
0.1 | 0.1 | GO:0003221 | right ventricular cardiac muscle tissue morphogenesis(GO:0003221) |
0.1 | 3.2 | GO:0051973 | positive regulation of telomerase activity(GO:0051973) |
0.1 | 0.2 | GO:1904016 | response to Thyroglobulin triiodothyronine(GO:1904016) |
0.1 | 1.1 | GO:0036158 | outer dynein arm assembly(GO:0036158) |
0.1 | 0.3 | GO:0006680 | glucosylceramide catabolic process(GO:0006680) |
0.0 | 1.6 | GO:0048148 | behavioral response to cocaine(GO:0048148) |
0.0 | 0.6 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304) |
0.0 | 0.7 | GO:0021694 | cerebellar Purkinje cell layer formation(GO:0021694) cerebellar Purkinje cell differentiation(GO:0021702) |
0.0 | 0.6 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
0.0 | 0.2 | GO:0097676 | histone H3-K36 dimethylation(GO:0097676) |
0.0 | 0.8 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.7 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
0.0 | 0.3 | GO:0007185 | transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185) |
0.0 | 3.4 | GO:0010830 | regulation of myotube differentiation(GO:0010830) |
0.0 | 0.2 | GO:0034773 | histone H4-K20 trimethylation(GO:0034773) |
0.0 | 0.6 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.0 | 0.4 | GO:0018095 | protein polyglutamylation(GO:0018095) |
0.0 | 0.2 | GO:1900920 | regulation of amino acid uptake involved in synaptic transmission(GO:0051941) regulation of glutamate uptake involved in transmission of nerve impulse(GO:0051946) regulation of L-glutamate import(GO:1900920) |
0.0 | 0.6 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
0.0 | 0.1 | GO:0044313 | protein K6-linked deubiquitination(GO:0044313) |
0.0 | 0.2 | GO:0021615 | glossopharyngeal nerve morphogenesis(GO:0021615) |
0.0 | 0.6 | GO:0070935 | 3'-UTR-mediated mRNA stabilization(GO:0070935) |
0.0 | 0.5 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
0.0 | 0.2 | GO:2000807 | regulation of synaptic vesicle clustering(GO:2000807) |
0.0 | 1.0 | GO:0061099 | negative regulation of protein tyrosine kinase activity(GO:0061099) |
0.0 | 0.2 | GO:0060633 | negative regulation of transcription initiation from RNA polymerase II promoter(GO:0060633) |
0.0 | 0.2 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.0 | 0.1 | GO:0051771 | negative regulation of nitric-oxide synthase biosynthetic process(GO:0051771) |
0.0 | 0.2 | GO:0016191 | synaptic vesicle uncoating(GO:0016191) |
0.0 | 0.2 | GO:0070934 | CRD-mediated mRNA stabilization(GO:0070934) |
0.0 | 0.5 | GO:0036148 | phosphatidylglycerol acyl-chain remodeling(GO:0036148) |
0.0 | 0.1 | GO:0006499 | N-terminal protein myristoylation(GO:0006499) |
0.0 | 0.5 | GO:0072189 | ureter development(GO:0072189) |
0.0 | 0.8 | GO:0044803 | multi-organism membrane organization(GO:0044803) |
0.0 | 0.2 | GO:0086024 | adrenergic receptor signaling pathway involved in positive regulation of heart rate(GO:0086024) |
0.0 | 0.8 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.0 | 0.1 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
0.0 | 0.5 | GO:0035024 | negative regulation of Rho protein signal transduction(GO:0035024) |
0.0 | 0.1 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
0.0 | 0.1 | GO:0060061 | Spemann organizer formation(GO:0060061) |
0.0 | 0.1 | GO:0061002 | negative regulation of dendritic spine morphogenesis(GO:0061002) |
0.0 | 0.2 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
0.0 | 0.1 | GO:1904153 | negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153) |
0.0 | 0.4 | GO:0007638 | mechanosensory behavior(GO:0007638) |
0.0 | 0.5 | GO:0048169 | regulation of long-term neuronal synaptic plasticity(GO:0048169) |
0.0 | 0.1 | GO:0001955 | blood vessel maturation(GO:0001955) negative regulation of metalloendopeptidase activity(GO:1904684) |
0.0 | 0.0 | GO:0035621 | ER to Golgi ceramide transport(GO:0035621) |
0.0 | 0.4 | GO:0048240 | sperm capacitation(GO:0048240) |
0.0 | 0.2 | GO:0016024 | CDP-diacylglycerol biosynthetic process(GO:0016024) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 3.5 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.2 | 0.7 | GO:0019034 | viral replication complex(GO:0019034) |
0.1 | 1.1 | GO:0036157 | outer dynein arm(GO:0036157) |
0.1 | 1.6 | GO:0097440 | apical dendrite(GO:0097440) |
0.1 | 0.6 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
0.0 | 0.3 | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) |
0.0 | 0.3 | GO:0042584 | chromaffin granule membrane(GO:0042584) |
0.0 | 3.9 | GO:0035577 | azurophil granule membrane(GO:0035577) |
0.0 | 1.8 | GO:0005790 | smooth endoplasmic reticulum(GO:0005790) |
0.0 | 0.5 | GO:0005664 | origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664) |
0.0 | 0.1 | GO:0005953 | CAAX-protein geranylgeranyltransferase complex(GO:0005953) |
0.0 | 0.1 | GO:0000836 | Hrd1p ubiquitin ligase complex(GO:0000836) |
0.0 | 0.4 | GO:0097524 | sperm plasma membrane(GO:0097524) |
0.0 | 0.4 | GO:0044666 | MLL3/4 complex(GO:0044666) |
0.0 | 0.2 | GO:0097452 | GAIT complex(GO:0097452) |
0.0 | 1.4 | GO:0043198 | dendritic shaft(GO:0043198) |
0.0 | 0.1 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
0.0 | 0.2 | GO:0042272 | nuclear RNA export factor complex(GO:0042272) |
0.0 | 0.1 | GO:0032444 | activin responsive factor complex(GO:0032444) |
0.0 | 1.0 | GO:0005720 | nuclear heterochromatin(GO:0005720) |
0.0 | 0.1 | GO:1990769 | proximal neuron projection(GO:1990769) |
0.0 | 0.3 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
0.0 | 1.0 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 0.4 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
0.0 | 0.7 | GO:0048786 | presynaptic active zone(GO:0048786) |
0.0 | 0.0 | GO:0043291 | RAVE complex(GO:0043291) |
0.0 | 0.1 | GO:0005677 | chromatin silencing complex(GO:0005677) |
0.0 | 0.2 | GO:0044798 | nuclear transcription factor complex(GO:0044798) |
0.0 | 0.1 | GO:0071458 | integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) |
0.0 | 0.3 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 1.2 | GO:0016459 | myosin complex(GO:0016459) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 3.9 | GO:0019763 | immunoglobulin receptor activity(GO:0019763) |
0.3 | 1.3 | GO:0000822 | inositol hexakisphosphate binding(GO:0000822) |
0.2 | 1.0 | GO:0030292 | protein tyrosine kinase inhibitor activity(GO:0030292) |
0.2 | 0.6 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
0.2 | 0.6 | GO:0032184 | SUMO polymer binding(GO:0032184) |
0.1 | 1.0 | GO:0016403 | dimethylargininase activity(GO:0016403) |
0.1 | 0.7 | GO:0004430 | 1-phosphatidylinositol 4-kinase activity(GO:0004430) |
0.1 | 1.5 | GO:0015467 | G-protein activated inward rectifier potassium channel activity(GO:0015467) |
0.1 | 0.5 | GO:0042285 | UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285) |
0.1 | 0.6 | GO:0004534 | 5'-3' exoribonuclease activity(GO:0004534) |
0.1 | 0.7 | GO:0008142 | oxysterol binding(GO:0008142) |
0.1 | 1.2 | GO:0042975 | peroxisome proliferator activated receptor binding(GO:0042975) |
0.1 | 0.5 | GO:0046912 | transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912) |
0.1 | 0.2 | GO:0010861 | thyroid hormone receptor activator activity(GO:0010861) thyroid hormone receptor coactivator activity(GO:0030375) |
0.1 | 0.3 | GO:0008422 | glucosylceramidase activity(GO:0004348) beta-glucosidase activity(GO:0008422) |
0.1 | 0.2 | GO:0032427 | GBD domain binding(GO:0032427) |
0.0 | 1.9 | GO:1990841 | promoter-specific chromatin binding(GO:1990841) |
0.0 | 1.1 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
0.0 | 0.5 | GO:0004445 | inositol-polyphosphate 5-phosphatase activity(GO:0004445) phosphatidylinositol-3,4,5-trisphosphate 5-phosphatase activity(GO:0034485) |
0.0 | 0.2 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.0 | 0.5 | GO:0005375 | copper ion transmembrane transporter activity(GO:0005375) |
0.0 | 0.4 | GO:0042731 | PH domain binding(GO:0042731) |
0.0 | 0.6 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
0.0 | 0.4 | GO:0070740 | tubulin-glutamic acid ligase activity(GO:0070740) |
0.0 | 0.2 | GO:0005315 | inorganic phosphate transmembrane transporter activity(GO:0005315) |
0.0 | 4.5 | GO:0003730 | mRNA 3'-UTR binding(GO:0003730) |
0.0 | 0.2 | GO:0034046 | poly(G) binding(GO:0034046) |
0.0 | 0.5 | GO:0017162 | aryl hydrocarbon receptor binding(GO:0017162) |
0.0 | 0.5 | GO:0047144 | 2-acylglycerol-3-phosphate O-acyltransferase activity(GO:0047144) |
0.0 | 0.3 | GO:0000155 | phosphorelay sensor kinase activity(GO:0000155) |
0.0 | 0.6 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.0 | 0.1 | GO:0004662 | CAAX-protein geranylgeranyltransferase activity(GO:0004662) |
0.0 | 0.2 | GO:0001727 | lipid kinase activity(GO:0001727) |
0.0 | 0.3 | GO:0070324 | thyroid hormone binding(GO:0070324) |
0.0 | 0.5 | GO:0003688 | DNA replication origin binding(GO:0003688) |
0.0 | 0.3 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.0 | 0.2 | GO:0061665 | SUMO ligase activity(GO:0061665) |
0.0 | 0.2 | GO:0008046 | axon guidance receptor activity(GO:0008046) |
0.0 | 0.6 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
0.0 | 0.5 | GO:0030955 | potassium ion binding(GO:0030955) |
0.0 | 0.6 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
0.0 | 0.4 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.0 | 0.2 | GO:0000182 | rDNA binding(GO:0000182) |
0.0 | 0.2 | GO:0031698 | beta-2 adrenergic receptor binding(GO:0031698) |
0.0 | 0.2 | GO:0003841 | 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) |
0.0 | 0.1 | GO:0033192 | calmodulin-dependent protein phosphatase activity(GO:0033192) |
0.0 | 0.2 | GO:0015271 | outward rectifier potassium channel activity(GO:0015271) |
0.0 | 0.2 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.0 | 0.3 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 0.3 | ST_JAK_STAT_PATHWAY | Jak-STAT Pathway |
0.0 | 1.2 | PID_HDAC_CLASSIII_PATHWAY | Signaling events mediated by HDAC Class III |
0.0 | 0.7 | PID_ERB_GENOMIC_PATHWAY | Validated nuclear estrogen receptor beta network |
0.0 | 2.9 | PID_IL4_2PATHWAY | IL4-mediated signaling events |
0.0 | 0.6 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 0.8 | ST_WNT_BETA_CATENIN_PATHWAY | Wnt/beta-catenin Pathway |
0.0 | 3.3 | NABA_ECM_AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
0.0 | 1.0 | PID_HNF3A_PATHWAY | FOXA1 transcription factor network |
0.0 | 0.4 | PID_EPHA_FWDPATHWAY | EPHA forward signaling |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.8 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
0.0 | 1.5 | REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA | Genes involved in Circadian Repression of Expression by REV-ERBA |
0.0 | 1.5 | REACTOME_INHIBITION_OF_VOLTAGE_GATED_CA2_CHANNELS_VIA_GBETA_GAMMA_SUBUNITS | Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits |
0.0 | 0.7 | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
0.0 | 0.5 | REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
0.0 | 0.6 | REACTOME_MRNA_DECAY_BY_5_TO_3_EXORIBONUCLEASE | Genes involved in mRNA Decay by 5' to 3' Exoribonuclease |
0.0 | 0.5 | REACTOME_ACYL_CHAIN_REMODELLING_OF_PG | Genes involved in Acyl chain remodelling of PG |
0.0 | 1.0 | REACTOME_SIGNALING_BY_FGFR1_FUSION_MUTANTS | Genes involved in Signaling by FGFR1 fusion mutants |
0.0 | 0.5 | REACTOME_SYNTHESIS_OF_PIPS_AT_THE_GOLGI_MEMBRANE | Genes involved in Synthesis of PIPs at the Golgi membrane |
0.0 | 1.1 | REACTOME_GLYCOSPHINGOLIPID_METABOLISM | Genes involved in Glycosphingolipid metabolism |
0.0 | 0.6 | REACTOME_METAL_ION_SLC_TRANSPORTERS | Genes involved in Metal ion SLC transporters |
0.0 | 0.5 | REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
0.0 | 0.3 | REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS | Genes involved in Glucagon-type ligand receptors |
0.0 | 1.0 | REACTOME_GOLGI_ASSOCIATED_VESICLE_BIOGENESIS | Genes involved in Golgi Associated Vesicle Biogenesis |