Motif ID: GCM2

Z-value: 0.774


Transcription factors associated with GCM2:

Gene SymbolEntrez IDGene Name
GCM2 ENSG00000124827.6 GCM2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
GCM2hg19_v2_chr6_-_10882174_108822740.281.8e-01Click!


Activity profile for motif GCM2.

activity profile for motif GCM2


Sorted Z-values histogram for motif GCM2

Sorted Z-values for motif GCM2



Network of associatons between targets according to the STRING database.



First level regulatory network of GCM2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_86511549 1.109 ENST00000533902.2
PRSS23
protease, serine, 23
chr1_-_223537401 1.080 ENST00000343846.3
ENST00000454695.2
ENST00000484758.2
SUSD4


sushi domain containing 4


chr5_-_54281407 1.063 ENST00000381403.4
ESM1
endothelial cell-specific molecule 1
chr1_-_223537475 1.009 ENST00000344029.6
ENST00000494793.2
ENST00000366878.4
ENST00000366877.3
SUSD4



sushi domain containing 4



chr15_-_75248954 0.926 ENST00000499788.2
RPP25
ribonuclease P/MRP 25kDa subunit
chr11_-_118023490 0.888 ENST00000324727.4
SCN4B
sodium channel, voltage-gated, type IV, beta subunit
chr15_-_93632421 0.887 ENST00000329082.7
RGMA
repulsive guidance molecule family member a
chr14_+_75536335 0.852 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C



zinc finger, C2HC-type containing 1C



chr14_+_75536280 0.822 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr17_+_53342311 0.745 ENST00000226067.5
HLF
hepatic leukemia factor
chr15_-_45670924 0.731 ENST00000396659.3
GATM
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr20_+_42086525 0.731 ENST00000244020.3
SRSF6
serine/arginine-rich splicing factor 6
chr14_+_77648167 0.724 ENST00000554346.1
ENST00000298351.4
TMEM63C

transmembrane protein 63C

chr14_-_67982146 0.687 ENST00000557779.1
ENST00000557006.1
TMEM229B

transmembrane protein 229B

chr9_-_130635741 0.666 ENST00000223836.10
AK1
adenylate kinase 1
chr14_+_21359558 0.652 ENST00000304639.3
RNASE3
ribonuclease, RNase A family, 3
chr14_-_67981916 0.636 ENST00000357461.2
TMEM229B
transmembrane protein 229B
chr15_+_78556809 0.621 ENST00000343789.3
ENST00000394852.3
DNAJA4

DnaJ (Hsp40) homolog, subfamily A, member 4

chr15_+_43809797 0.604 ENST00000399453.1
ENST00000300231.5
MAP1A

microtubule-associated protein 1A

chr16_+_28996364 0.602 ENST00000564277.1
LAT
linker for activation of T cells
chr1_+_20878932 0.565 ENST00000332947.4
FAM43B
family with sequence similarity 43, member B
chr14_-_24911448 0.555 ENST00000555355.1
ENST00000553343.1
ENST00000556523.1
ENST00000556249.1
ENST00000538105.2
ENST00000555225.1
SDR39U1





short chain dehydrogenase/reductase family 39U, member 1





chr19_-_14316980 0.550 ENST00000361434.3
ENST00000340736.6
LPHN1

latrophilin 1

chr9_-_99381660 0.531 ENST00000375240.3
ENST00000463569.1
CDC14B

cell division cycle 14B

chr5_+_122847908 0.521 ENST00000511130.2
ENST00000512718.3
CSNK1G3

casein kinase 1, gamma 3

chr1_+_46640750 0.472 ENST00000372003.1
TSPAN1
tetraspanin 1
chr12_+_15125954 0.455 ENST00000266395.2
PDE6H
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr15_-_48470544 0.454 ENST00000267836.6
MYEF2
myelin expression factor 2
chr14_-_24912047 0.444 ENST00000553930.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr16_+_22825475 0.441 ENST00000261374.3
HS3ST2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr5_-_138718973 0.440 ENST00000353963.3
ENST00000348729.3
SLC23A1

solute carrier family 23 (ascorbic acid transporter), member 1

chr12_-_322504 0.434 ENST00000424061.2
SLC6A12
solute carrier family 6 (neurotransmitter transporter), member 12
chr7_-_105319536 0.427 ENST00000477775.1
ATXN7L1
ataxin 7-like 1
chr7_+_37960163 0.423 ENST00000199448.4
ENST00000559325.1
ENST00000423717.1
EPDR1


ependymin related 1


chr6_+_7108210 0.413 ENST00000467782.1
ENST00000334984.6
ENST00000349384.6
RREB1


ras responsive element binding protein 1


chr14_+_23352374 0.412 ENST00000267396.4
ENST00000536884.1
REM2

RAS (RAD and GEM)-like GTP binding 2

chr6_+_7107830 0.405 ENST00000379933.3
RREB1
ras responsive element binding protein 1
chr14_-_67981870 0.394 ENST00000555994.1
TMEM229B
transmembrane protein 229B
chr15_+_89164520 0.393 ENST00000332810.3
AEN
apoptosis enhancing nuclease
chr7_+_99933730 0.392 ENST00000610247.1
PILRB
paired immunoglobin-like type 2 receptor beta
chr3_+_50712672 0.390 ENST00000266037.9
DOCK3
dedicator of cytokinesis 3
chr16_+_30759700 0.386 ENST00000328273.7
PHKG2
phosphorylase kinase, gamma 2 (testis)
chr14_-_24911868 0.385 ENST00000554698.1
SDR39U1
short chain dehydrogenase/reductase family 39U, member 1
chr14_-_24911971 0.384 ENST00000555365.1
ENST00000399395.3
SDR39U1

short chain dehydrogenase/reductase family 39U, member 1

chr19_+_10531150 0.382 ENST00000352831.6
PDE4A
phosphodiesterase 4A, cAMP-specific
chr2_+_73114489 0.369 ENST00000234454.5
SPR
sepiapterin reductase (7,8-dihydrobiopterin:NADP+ oxidoreductase)
chr22_-_31741757 0.363 ENST00000215919.3
PATZ1
POZ (BTB) and AT hook containing zinc finger 1
chr8_-_98290087 0.353 ENST00000322128.3
TSPYL5
TSPY-like 5
chr11_-_10715117 0.349 ENST00000527509.2
MRVI1
murine retrovirus integration site 1 homolog
chr19_-_46288917 0.346 ENST00000537879.1
ENST00000596586.1
ENST00000595946.1
DMWD
AC011530.4

dystrophia myotonica, WD repeat containing
Uncharacterized protein

chr14_-_105635090 0.344 ENST00000331782.3
ENST00000347004.2
JAG2

jagged 2

chr2_+_12857015 0.338 ENST00000155926.4
TRIB2
tribbles pseudokinase 2
chr7_+_6048856 0.336 ENST00000223029.3
ENST00000400479.2
ENST00000395236.2
AIMP2


aminoacyl tRNA synthetase complex-interacting multifunctional protein 2


chr3_+_137490748 0.328 ENST00000478772.1
RP11-2A4.3
RP11-2A4.3
chr7_-_98467489 0.328 ENST00000416379.2
TMEM130
transmembrane protein 130
chr7_+_70597109 0.327 ENST00000333538.5
WBSCR17
Williams-Beuren syndrome chromosome region 17
chr2_-_40739501 0.321 ENST00000403092.1
ENST00000402441.1
ENST00000448531.1
SLC8A1


solute carrier family 8 (sodium/calcium exchanger), member 1


chr8_+_134125727 0.320 ENST00000521107.1
TG
thyroglobulin
chr15_+_74466744 0.319 ENST00000560862.1
ENST00000395118.1
ISLR

immunoglobulin superfamily containing leucine-rich repeat

chr2_+_12857043 0.315 ENST00000381465.2
TRIB2
tribbles pseudokinase 2
chr2_+_179059365 0.314 ENST00000190611.4
OSBPL6
oxysterol binding protein-like 6
chr6_-_31239846 0.310 ENST00000415537.1
ENST00000376228.5
ENST00000383329.3
HLA-C


major histocompatibility complex, class I, C


chr2_+_16080659 0.301 ENST00000281043.3
MYCN
v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog
chr1_-_205313304 0.296 ENST00000539253.1
ENST00000607826.1
KLHDC8A

kelch domain containing 8A

chr8_+_37553261 0.292 ENST00000331569.4
ZNF703
zinc finger protein 703
chr11_+_64009072 0.287 ENST00000535135.1
ENST00000394540.3
FKBP2

FK506 binding protein 2, 13kDa

chr19_+_14142535 0.287 ENST00000263379.2
IL27RA
interleukin 27 receptor, alpha
chr16_+_57438679 0.286 ENST00000219244.4
CCL17
chemokine (C-C motif) ligand 17
chr3_-_142682178 0.286 ENST00000340634.3
PAQR9
progestin and adipoQ receptor family member IX
chr22_-_30783356 0.280 ENST00000382363.3
RNF215
ring finger protein 215
chr11_-_83393457 0.277 ENST00000404783.3
DLG2
discs, large homolog 2 (Drosophila)
chr3_-_121740969 0.275 ENST00000393631.1
ENST00000273691.3
ENST00000344209.5
ILDR1


immunoglobulin-like domain containing receptor 1


chr1_+_180601139 0.273 ENST00000367590.4
ENST00000367589.3
XPR1

xenotropic and polytropic retrovirus receptor 1

chr15_-_88799384 0.273 ENST00000540489.2
ENST00000557856.1
ENST00000558676.1
NTRK3


neurotrophic tyrosine kinase, receptor, type 3


chr6_-_32077100 0.262 ENST00000375244.3
ENST00000375247.2
TNXB

tenascin XB

chr11_+_86511569 0.260 ENST00000441050.1
PRSS23
protease, serine, 23
chr22_-_43090992 0.260 ENST00000401850.1
A4GALT
alpha 1,4-galactosyltransferase
chr5_+_140345820 0.258 ENST00000289269.5
PCDHAC2
protocadherin alpha subfamily C, 2
chr1_+_61548225 0.257 ENST00000371187.3
NFIA
nuclear factor I/A
chr3_+_35681728 0.255 ENST00000421492.1
ENST00000458225.1
ENST00000337271.5
ARPP21


cAMP-regulated phosphoprotein, 21kDa


chr19_+_55014085 0.255 ENST00000351841.2
LAIR2
leukocyte-associated immunoglobulin-like receptor 2
chr7_-_6048702 0.254 ENST00000265849.7
PMS2
PMS2 postmeiotic segregation increased 2 (S. cerevisiae)
chr19_+_17581253 0.254 ENST00000252595.7
ENST00000598424.1
SLC27A1

solute carrier family 27 (fatty acid transporter), member 1

chr3_-_45838011 0.250 ENST00000358525.4
ENST00000413781.1
SLC6A20

solute carrier family 6 (proline IMINO transporter), member 20

chr5_+_177027101 0.249 ENST00000029410.5
ENST00000510761.1
ENST00000505468.1
B4GALT7


xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7


chr16_+_28996572 0.248 ENST00000360872.5
ENST00000566177.1
ENST00000354453.4
LAT


linker for activation of T cells


chr15_-_48470558 0.245 ENST00000324324.7
MYEF2
myelin expression factor 2
chr19_+_55014013 0.243 ENST00000301202.2
LAIR2
leukocyte-associated immunoglobulin-like receptor 2
chr3_-_50605150 0.243 ENST00000357203.3
C3orf18
chromosome 3 open reading frame 18
chr17_-_7123021 0.242 ENST00000399510.2
DLG4
discs, large homolog 4 (Drosophila)
chr1_+_15272271 0.241 ENST00000400797.3
KAZN
kazrin, periplakin interacting protein
chr7_-_6048650 0.239 ENST00000382321.4
ENST00000406569.3
PMS2

PMS2 postmeiotic segregation increased 2 (S. cerevisiae)

chr1_+_170501270 0.239 ENST00000367763.3
ENST00000367762.1
GORAB

golgin, RAB6-interacting

chr15_+_40733387 0.238 ENST00000416165.1
BAHD1
bromo adjacent homology domain containing 1
chr19_-_10676666 0.237 ENST00000539027.1
ENST00000543682.1
ENST00000361821.5
ENST00000312962.6
KRI1



KRI1 homolog (S. cerevisiae)



chr3_-_45837959 0.234 ENST00000353278.4
ENST00000456124.2
SLC6A20

solute carrier family 6 (proline IMINO transporter), member 20

chr19_+_36208877 0.233 ENST00000420124.1
ENST00000222270.7
ENST00000341701.1
KMT2B


Histone-lysine N-methyltransferase 2B


chr2_-_27603582 0.233 ENST00000323703.6
ENST00000436006.1
ZNF513

zinc finger protein 513

chr20_+_42143136 0.233 ENST00000373134.1
L3MBTL1
l(3)mbt-like 1 (Drosophila)
chr17_-_3796334 0.233 ENST00000381771.2
ENST00000348335.2
ENST00000158166.5
CAMKK1


calcium/calmodulin-dependent protein kinase kinase 1, alpha


chr1_+_214161272 0.233 ENST00000498508.2
ENST00000366958.4
PROX1

prospero homeobox 1

chr6_+_31021973 0.232 ENST00000570223.1
ENST00000566475.1
ENST00000426185.1
HCG22


HLA complex group 22


chr16_+_30759563 0.232 ENST00000563588.1
ENST00000565924.1
ENST00000424889.3
PHKG2


phosphorylase kinase, gamma 2 (testis)


chr9_+_140317802 0.230 ENST00000341349.2
ENST00000392815.2
NOXA1

NADPH oxidase activator 1

chr17_+_28256874 0.229 ENST00000541045.1
ENST00000536908.2
EFCAB5

EF-hand calcium binding domain 5

chr4_-_74864386 0.227 ENST00000296027.4
CXCL5
chemokine (C-X-C motif) ligand 5
chr3_-_50605077 0.227 ENST00000426034.1
ENST00000441239.1
C3orf18

chromosome 3 open reading frame 18

chr10_+_102790980 0.225 ENST00000393459.1
ENST00000224807.5
SFXN3

sideroflexin 3

chr22_-_20307532 0.225 ENST00000405465.3
ENST00000248879.3
DGCR6L

DiGeorge syndrome critical region gene 6-like

chr2_-_220435963 0.221 ENST00000373876.1
ENST00000404537.1
ENST00000603926.1
ENST00000373873.4
ENST00000289656.3
OBSL1




obscurin-like 1




chr17_-_72358001 0.220 ENST00000375366.3
BTBD17
BTB (POZ) domain containing 17
chr12_-_48398104 0.218 ENST00000337299.6
ENST00000380518.3
COL2A1

collagen, type II, alpha 1

chr3_+_131100515 0.217 ENST00000537561.1
ENST00000359850.3
ENST00000521288.1
ENST00000502852.1
NUDT16



nudix (nucleoside diphosphate linked moiety X)-type motif 16



chrX_+_130192318 0.217 ENST00000370922.1
ARHGAP36
Rho GTPase activating protein 36
chr17_-_27332931 0.216 ENST00000442608.3
ENST00000335960.6
SEZ6

seizure related 6 homolog (mouse)

chr11_+_63706444 0.215 ENST00000377793.4
ENST00000456907.2
ENST00000539656.1
NAA40


N(alpha)-acetyltransferase 40, NatD catalytic subunit


chr14_+_105046021 0.214 ENST00000557649.1
C14orf180
chromosome 14 open reading frame 180
chr2_+_179059188 0.212 ENST00000392505.2
ENST00000359685.3
ENST00000357080.4
ENST00000409045.3
OSBPL6



oxysterol binding protein-like 6



chr2_-_220252603 0.210 ENST00000322176.7
ENST00000273075.4
DNPEP

aspartyl aminopeptidase

chr17_+_17206635 0.209 ENST00000389022.4
NT5M
5',3'-nucleotidase, mitochondrial
chr11_-_5345582 0.209 ENST00000328813.2
OR51B2
olfactory receptor, family 51, subfamily B, member 2
chr14_-_59932044 0.207 ENST00000395116.1
GPR135
G protein-coupled receptor 135
chr14_-_21567009 0.207 ENST00000556174.1
ENST00000554478.1
ENST00000553980.1
ENST00000421093.2
ZNF219



zinc finger protein 219



chr12_-_49582593 0.207 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr14_-_21566731 0.206 ENST00000360947.3
ZNF219
zinc finger protein 219
chr2_-_193059634 0.205 ENST00000392314.1
TMEFF2
transmembrane protein with EGF-like and two follistatin-like domains 2
chrX_+_12156582 0.202 ENST00000380682.1
FRMPD4
FERM and PDZ domain containing 4
chr6_-_150039170 0.200 ENST00000458696.2
ENST00000392273.3
LATS1

large tumor suppressor kinase 1

chr11_+_92085262 0.200 ENST00000298047.6
ENST00000409404.2
ENST00000541502.1
FAT3


FAT atypical cadherin 3


chr19_-_38878632 0.196 ENST00000586599.1
ENST00000334928.6
ENST00000587676.1
GGN


gametogenetin


chr16_+_28996114 0.194 ENST00000395461.3
LAT
linker for activation of T cells
chr3_-_11762202 0.193 ENST00000445411.1
ENST00000404339.1
ENST00000273038.3
VGLL4


vestigial like 4 (Drosophila)


chr1_-_228613026 0.192 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chr20_+_42143053 0.190 ENST00000373135.3
ENST00000444063.1
L3MBTL1

l(3)mbt-like 1 (Drosophila)

chr19_+_37178482 0.186 ENST00000536254.2
ZNF567
zinc finger protein 567
chr22_-_37545972 0.183 ENST00000216223.5
IL2RB
interleukin 2 receptor, beta
chr19_+_22469236 0.183 ENST00000357491.6
ZNF729
zinc finger protein 729
chr5_-_160975130 0.182 ENST00000274547.2
ENST00000520240.1
ENST00000517901.1
ENST00000353437.6
GABRB2



gamma-aminobutyric acid (GABA) A receptor, beta 2



chr12_+_5541267 0.182 ENST00000423158.3
NTF3
neurotrophin 3
chr2_-_220436248 0.181 ENST00000265318.4
OBSL1
obscurin-like 1
chr17_-_42907564 0.180 ENST00000592524.1
GJC1
gap junction protein, gamma 1, 45kDa
chr9_+_139606983 0.179 ENST00000371692.4
FAM69B
family with sequence similarity 69, member B
chr1_+_237205476 0.178 ENST00000366574.2
RYR2
ryanodine receptor 2 (cardiac)
chr2_-_19558373 0.177 ENST00000272223.2
OSR1
odd-skipped related transciption factor 1
chr9_+_4490394 0.174 ENST00000262352.3
SLC1A1
solute carrier family 1 (neuronal/epithelial high affinity glutamate transporter, system Xag), member 1
chr20_-_31172598 0.171 ENST00000201961.2
C20orf112
chromosome 20 open reading frame 112
chr14_+_104604916 0.171 ENST00000423312.2
KIF26A
kinesin family member 26A
chr17_-_41132010 0.170 ENST00000409103.1
ENST00000360221.4
PTGES3L-AARSD1

PTGES3L-AARSD1 readthrough

chr9_-_99417562 0.170 ENST00000375234.3
ENST00000446045.1
AAED1

AhpC/TSA antioxidant enzyme domain containing 1

chr14_-_77737543 0.169 ENST00000298352.4
NGB
neuroglobin
chr17_-_7218631 0.168 ENST00000577040.2
ENST00000389167.5
ENST00000391950.3
GPS2


G protein pathway suppressor 2


chr15_+_40731920 0.168 ENST00000561234.1
BAHD1
bromo adjacent homology domain containing 1
chr5_+_139493665 0.168 ENST00000331327.3
PURA
purine-rich element binding protein A
chr11_-_9113137 0.165 ENST00000520467.1
ENST00000309263.3
ENST00000457346.2
SCUBE2


signal peptide, CUB domain, EGF-like 2


chr15_+_89010923 0.164 ENST00000353598.6
MRPS11
mitochondrial ribosomal protein S11
chr5_-_54281491 0.163 ENST00000381405.4
ESM1
endothelial cell-specific molecule 1
chr5_+_122847781 0.159 ENST00000395412.1
ENST00000395411.1
ENST00000345990.4
CSNK1G3


casein kinase 1, gamma 3


chr19_-_19626351 0.158 ENST00000585580.3
TSSK6
testis-specific serine kinase 6
chr1_-_167906277 0.157 ENST00000271373.4
MPC2
mitochondrial pyruvate carrier 2
chr19_+_19496728 0.157 ENST00000537887.1
ENST00000417582.2
GATAD2A

GATA zinc finger domain containing 2A

chr3_+_186383741 0.155 ENST00000232003.4
HRG
histidine-rich glycoprotein
chr19_+_19626531 0.154 ENST00000507754.4
NDUFA13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr6_-_32077078 0.154 ENST00000479795.1
TNXB
tenascin XB
chr1_+_28099683 0.150 ENST00000373943.4
STX12
syntaxin 12
chr1_+_158325684 0.142 ENST00000368162.2
CD1E
CD1e molecule
chr7_+_148395959 0.140 ENST00000325222.4
CUL1
cullin 1
chr17_-_8021710 0.139 ENST00000380149.1
ENST00000448843.2
ALOXE3

arachidonate lipoxygenase 3

chr18_+_3449695 0.139 ENST00000343820.5
TGIF1
TGFB-induced factor homeobox 1
chr13_-_45010939 0.137 ENST00000261489.2
TSC22D1
TSC22 domain family, member 1
chr6_+_46761118 0.137 ENST00000230588.4
MEP1A
meprin A, alpha (PABA peptide hydrolase)
chr2_+_220299547 0.135 ENST00000312358.7
SPEG
SPEG complex locus
chr2_+_220408724 0.134 ENST00000421791.1
ENST00000373883.3
ENST00000451952.1
TMEM198


transmembrane protein 198


chr6_-_138539627 0.134 ENST00000527246.2
PBOV1
prostate and breast cancer overexpressed 1
chr6_-_52859968 0.133 ENST00000370959.1
GSTA4
glutathione S-transferase alpha 4
chr19_-_10426663 0.131 ENST00000541276.1
ENST00000393708.3
ENST00000494368.1
FDX1L


ferredoxin 1-like


chr22_-_30662828 0.130 ENST00000403463.1
ENST00000215781.2
OSM

oncostatin M

chr3_+_35681081 0.128 ENST00000428373.1
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chrX_-_71526999 0.128 ENST00000453707.2
ENST00000373619.3
CITED1

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1

chr15_+_44069276 0.128 ENST00000381359.1
SERF2
small EDRK-rich factor 2
chr17_-_10017864 0.127 ENST00000323816.4
GAS7
growth arrest-specific 7
chr18_-_29264467 0.126 ENST00000383131.3
ENST00000237019.7
B4GALT6

UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6

chr6_-_13621126 0.125 ENST00000600057.1
AL441883.1
Uncharacterized protein
chr2_-_33824336 0.122 ENST00000431950.1
ENST00000403368.1
ENST00000441530.2
FAM98A


family with sequence similarity 98, member A


chr1_-_155532484 0.121 ENST00000368346.3
ENST00000548830.1
ASH1L

ash1 (absent, small, or homeotic)-like (Drosophila)

chr2_-_33824382 0.121 ENST00000238823.8
FAM98A
family with sequence similarity 98, member A
chr2_+_233271546 0.120 ENST00000295453.3
ALPPL2
alkaline phosphatase, placental-like 2
chr11_+_63448918 0.120 ENST00000341307.2
ENST00000356000.3
ENST00000542238.1
RTN3


reticulon 3


chr2_-_219134822 0.120 ENST00000444053.1
ENST00000248450.4
AAMP

angio-associated, migratory cell protein

chr5_+_159343688 0.119 ENST00000306675.3
ADRA1B
adrenoceptor alpha 1B
chr10_-_99531709 0.118 ENST00000266066.3
SFRP5
secreted frizzled-related protein 5
chr12_+_54891495 0.118 ENST00000293373.6
NCKAP1L
NCK-associated protein 1-like
chr3_-_79068594 0.118 ENST00000436010.2
ROBO1
roundabout, axon guidance receptor, homolog 1 (Drosophila)
chr20_-_982904 0.116 ENST00000217260.4
ENST00000400634.2
RSPO4

R-spondin 4

chr1_-_156698591 0.115 ENST00000368219.1
ISG20L2
interferon stimulated exonuclease gene 20kDa-like 2
chrX_-_71526813 0.112 ENST00000246139.5
CITED1
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 1
chr3_-_12705600 0.111 ENST00000542177.1
ENST00000442415.2
ENST00000251849.4
RAF1


v-raf-1 murine leukemia viral oncogene homolog 1


chr12_+_50344516 0.111 ENST00000199280.3
ENST00000550862.1
AQP2

aquaporin 2 (collecting duct)

chr1_-_21503337 0.110 ENST00000400422.1
ENST00000602326.1
ENST00000411888.1
ENST00000438975.1
EIF4G3



eukaryotic translation initiation factor 4 gamma, 3



chr3_+_184032919 0.109 ENST00000427845.1
ENST00000342981.4
ENST00000319274.6
EIF4G1


eukaryotic translation initiation factor 4 gamma, 1


chr1_+_64239657 0.108 ENST00000371080.1
ENST00000371079.1
ROR1

receptor tyrosine kinase-like orphan receptor 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.2 0.7 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.4 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.7 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.4 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.6 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.3 GO:0019056 modulation by virus of host transcription(GO:0019056) positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691) modulation by symbiont of host transcription(GO:0052026)
0.1 0.7 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 0.2 GO:0090425 hepatocyte cell migration(GO:0002194) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.1 0.2 GO:0046709 IDP metabolic process(GO:0046707) IDP catabolic process(GO:0046709)
0.1 0.2 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 0.7 GO:0006600 creatine metabolic process(GO:0006600)
0.1 0.7 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.2 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) regulation of SA node cell action potential(GO:0098907)
0.1 0.2 GO:0072186 metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094)
0.1 0.2 GO:0001560 regulation of cell growth by extracellular stimulus(GO:0001560)
0.1 0.4 GO:0060120 auditory receptor cell fate commitment(GO:0009912) inner ear receptor cell fate commitment(GO:0060120)
0.1 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.2 GO:2001027 negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.9 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.9 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:1903630 regulation of aminoacyl-tRNA ligase activity(GO:1903630)
0.0 0.2 GO:0038110 interleukin-2-mediated signaling pathway(GO:0038110)
0.0 0.9 GO:0086016 AV node cell action potential(GO:0086016) AV node cell to bundle of His cell signaling(GO:0086027)
0.0 0.5 GO:0015824 proline transport(GO:0015824)
0.0 0.3 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.1 GO:0034553 respiratory chain complex II assembly(GO:0034552) mitochondrial respiratory chain complex II assembly(GO:0034553) mitochondrial respiratory chain complex II biogenesis(GO:0097032)
0.0 0.2 GO:0045113 regulation of integrin biosynthetic process(GO:0045113)
0.0 0.2 GO:0071105 response to interleukin-11(GO:0071105)
0.0 0.3 GO:0015705 iodide transport(GO:0015705)
0.0 0.1 GO:0021823 cerebral cortex tangential migration using cell-cell interactions(GO:0021823) postnatal olfactory bulb interneuron migration(GO:0021827) chemorepulsion involved in postnatal olfactory bulb interneuron migration(GO:0021836)
0.0 0.2 GO:1902361 mitochondrial pyruvate transport(GO:0006850) mitochondrial pyruvate transmembrane transport(GO:1902361)
0.0 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.4 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.0 0.3 GO:0071072 negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.3 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.0 0.5 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) endocardial cushion fusion(GO:0003274)
0.0 0.0 GO:0072197 ureter morphogenesis(GO:0072197)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0061188 negative regulation of chromatin silencing at rDNA(GO:0061188)
0.0 0.3 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.1 GO:0097676 histone H3-K36 dimethylation(GO:0097676)
0.0 0.1 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.6 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.0 0.2 GO:0000101 sulfur amino acid transport(GO:0000101)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.5 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0097688 AMPA glutamate receptor clustering(GO:0097113) glutamate receptor clustering(GO:0097688)
0.0 0.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.1 GO:0044691 tooth eruption(GO:0044691)
0.0 0.1 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.4 GO:0071688 striated muscle myosin thick filament assembly(GO:0071688)
0.0 0.1 GO:0007538 primary sex determination(GO:0007538)
0.0 0.1 GO:0001827 inner cell mass cell fate commitment(GO:0001827) inner cell mass cellular morphogenesis(GO:0001828)
0.0 0.2 GO:0010265 SCF complex assembly(GO:0010265)
0.0 0.5 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.3 GO:0048302 isotype switching to IgG isotypes(GO:0048291) regulation of isotype switching to IgG isotypes(GO:0048302)
0.0 0.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.2 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.2 GO:0046078 dUMP metabolic process(GO:0046078)
0.0 0.3 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.0 0.2 GO:0060174 limb bud formation(GO:0060174)
0.0 0.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.2 GO:0097167 circadian regulation of translation(GO:0097167)
0.0 0.1 GO:0021997 neural plate axis specification(GO:0021997)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0009386 translational attenuation(GO:0009386)
0.0 0.2 GO:0060263 regulation of respiratory burst(GO:0060263)
0.0 0.1 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165) negative regulation of chondrocyte proliferation(GO:1902731)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 1.0 GO:0043303 mast cell activation involved in immune response(GO:0002279) mast cell degranulation(GO:0043303)
0.0 0.4 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171)
0.0 2.2 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:1901620 regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901620)
0.0 0.3 GO:0072189 ureter development(GO:0072189)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 0.0 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:0033490 cholesterol biosynthetic process via desmosterol(GO:0033489) cholesterol biosynthetic process via lathosterol(GO:0033490)
0.0 0.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.0 0.2 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.1 GO:0010511 regulation of phosphatidylinositol biosynthetic process(GO:0010511) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.4 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.2 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.5 GO:0032389 MutLalpha complex(GO:0032389)
0.1 0.4 GO:1990393 3M complex(GO:1990393)
0.0 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.6 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.5 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 1.0 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.5 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.2 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.4 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.1 GO:0002139 stereocilia coupling link(GO:0002139)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.0 GO:0005956 protein kinase CK2 complex(GO:0005956)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.9 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.4 GO:0070890 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.4 GO:0032093 SAM domain binding(GO:0032093)
0.1 0.3 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.1 0.2 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.1 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.5 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.1 0.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.2 GO:0097158 pre-mRNA intronic pyrimidine-rich binding(GO:0097158)
0.1 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911) interleukin-2 binding(GO:0019976)
0.1 0.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 0.2 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.9 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.4 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.0 0.2 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.0 0.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.0 0.1 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.1 GO:0051120 hepoxilin A3 synthase activity(GO:0051120)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.5 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.1 GO:0036134 thromboxane-A synthase activity(GO:0004796) 12-hydroxyheptadecatrienoic acid synthase activity(GO:0036134)
0.0 0.1 GO:0050528 acyloxyacyl hydrolase activity(GO:0050528)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.3 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.2 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.0 0.5 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.1 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.8 GO:0031434 mitogen-activated protein kinase kinase binding(GO:0031434)
0.0 0.7 GO:0016769 transferase activity, transferring nitrogenous groups(GO:0016769)
0.0 0.2 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.3 GO:0031957 fatty acid transporter activity(GO:0015245) very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.1 GO:1904929 coreceptor activity involved in Wnt signaling pathway, planar cell polarity pathway(GO:1904929)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.5 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.2 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.4 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.1 GO:0030884 lipid antigen binding(GO:0030882) endogenous lipid antigen binding(GO:0030883) exogenous lipid antigen binding(GO:0030884)
0.0 0.2 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.0 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.5 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.1 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.3 GO:0042288 MHC class I protein binding(GO:0042288)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID_TCR_JNK_PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.1 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 1.3 NABA_PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID_CONE_PATHWAY Visual signal transduction: Cones

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.4 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.3 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.3 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 1.0 REACTOME_GENERATION_OF_SECOND_MESSENGER_MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.9 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.1 REACTOME_NETRIN1_SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.2 REACTOME_POST_NMDA_RECEPTOR_ACTIVATION_EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.2 REACTOME_PYRIMIDINE_CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.3 REACTOME_A_TETRASACCHARIDE_LINKER_SEQUENCE_IS_REQUIRED_FOR_GAG_SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.4 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis