Motif ID: GGAAUGU

Z-value: 0.366


Mature miRNA associated with seed GGAAUGU:

NamemiRBase Accession
hsa-miR-1-3p MIMAT0000416
hsa-miR-206 MIMAT0000462
hsa-miR-613 MIMAT0003281



Activity profile for motif GGAAUGU.

activity profile for motif GGAAUGU


Sorted Z-values histogram for motif GGAAUGU

Sorted Z-values for motif GGAAUGU



Network of associatons between targets according to the STRING database.



First level regulatory network of GGAAUGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_172756506 0.603 ENST00000265087.4
STC2
stanniocalcin 2
chr12_+_4382917 0.584 ENST00000261254.3
CCND2
cyclin D2
chr17_-_53499310 0.379 ENST00000262065.3
MMD
monocyte to macrophage differentiation-associated
chr4_-_111119804 0.310 ENST00000394607.3
ENST00000302274.3
ELOVL6

ELOVL fatty acid elongase 6

chr14_+_20937538 0.306 ENST00000361505.5
ENST00000553591.1
PNP

purine nucleoside phosphorylase

chr3_-_123603137 0.227 ENST00000360304.3
ENST00000359169.1
ENST00000346322.5
ENST00000360772.3
MYLK



myosin light chain kinase



chr20_+_49126881 0.226 ENST00000371621.3
ENST00000541713.1
PTPN1

protein tyrosine phosphatase, non-receptor type 1

chr1_-_179198702 0.224 ENST00000502732.1
ABL2
c-abl oncogene 2, non-receptor tyrosine kinase
chr15_+_39873268 0.223 ENST00000397591.2
ENST00000260356.5
THBS1

thrombospondin 1

chr7_-_92463210 0.223 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr9_+_131102925 0.207 ENST00000372870.1
ENST00000300456.4
SLC27A4

solute carrier family 27 (fatty acid transporter), member 4

chr10_-_33623564 0.204 ENST00000374875.1
ENST00000374822.4
NRP1

neuropilin 1

chr17_+_70117153 0.200 ENST00000245479.2
SOX9
SRY (sex determining region Y)-box 9
chr19_-_2151523 0.197 ENST00000350812.6
ENST00000355272.6
ENST00000356926.4
ENST00000345016.5
AP3D1



adaptor-related protein complex 3, delta 1 subunit



chr6_+_12290586 0.196 ENST00000379375.5
EDN1
endothelin 1
chr7_+_120628731 0.192 ENST00000310396.5
CPED1
cadherin-like and PC-esterase domain containing 1
chr8_-_49833978 0.191 ENST00000020945.1
SNAI2
snail family zinc finger 2
chr1_+_25943959 0.185 ENST00000374332.4
MAN1C1
mannosidase, alpha, class 1C, member 1
chr2_+_70142189 0.182 ENST00000264444.2
MXD1
MAX dimerization protein 1
chr17_-_41174424 0.173 ENST00000355653.3
VAT1
vesicle amine transport 1
chr10_+_102106829 0.160 ENST00000370355.2
SCD
stearoyl-CoA desaturase (delta-9-desaturase)
chr16_-_28222797 0.159 ENST00000569951.1
ENST00000565698.1
XPO6

exportin 6

chr11_-_128392085 0.155 ENST00000526145.2
ENST00000531611.1
ENST00000319397.6
ENST00000345075.4
ENST00000535549.1
ETS1




v-ets avian erythroblastosis virus E26 oncogene homolog 1




chr6_+_118228657 0.153 ENST00000360388.4
SLC35F1
solute carrier family 35, member F1
chr14_-_53258314 0.149 ENST00000216410.3
ENST00000557604.1
GNPNAT1

glucosamine-phosphate N-acetyltransferase 1

chr18_+_55711575 0.147 ENST00000356462.6
ENST00000400345.3
ENST00000589054.1
ENST00000256832.7
NEDD4L



neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase



chr19_-_6424783 0.142 ENST00000398148.3
KHSRP
KH-type splicing regulatory protein
chr7_+_100797678 0.141 ENST00000337619.5
AP1S1
adaptor-related protein complex 1, sigma 1 subunit
chr5_-_94620239 0.139 ENST00000515393.1
MCTP1
multiple C2 domains, transmembrane 1
chrX_+_41192595 0.138 ENST00000399959.2
DDX3X
DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked
chr5_+_151151471 0.136 ENST00000394123.3
ENST00000543466.1
G3BP1

GTPase activating protein (SH3 domain) binding protein 1

chr15_+_42066632 0.136 ENST00000457542.2
ENST00000221214.6
ENST00000260357.7
ENST00000456763.2
MAPKBP1



mitogen-activated protein kinase binding protein 1



chr12_-_109125285 0.134 ENST00000552871.1
ENST00000261401.3
CORO1C

coronin, actin binding protein, 1C

chr13_-_107187462 0.133 ENST00000245323.4
EFNB2
ephrin-B2
chr12_-_58146048 0.132 ENST00000547281.1
ENST00000546489.1
ENST00000552388.1
ENST00000540325.1
ENST00000312990.6
CDK4




cyclin-dependent kinase 4




chr17_+_14204389 0.130 ENST00000360954.2
HS3ST3B1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr11_+_69455855 0.129 ENST00000227507.2
ENST00000536559.1
CCND1

cyclin D1

chr1_+_84543734 0.128 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr9_-_110251836 0.127 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr8_-_41166953 0.127 ENST00000220772.3
SFRP1
secreted frizzled-related protein 1
chrX_-_20159934 0.125 ENST00000379593.1
ENST00000379607.5
EIF1AX

eukaryotic translation initiation factor 1A, X-linked

chr15_+_65134088 0.123 ENST00000323544.4
ENST00000437723.1
PLEKHO2
AC069368.3
pleckstrin homology domain containing, family O member 2
Uncharacterized protein
chr3_+_171758344 0.121 ENST00000336824.4
ENST00000423424.1
FNDC3B

fibronectin type III domain containing 3B

chr12_+_125478241 0.121 ENST00000341446.8
BRI3BP
BRI3 binding protein
chr13_+_47127293 0.119 ENST00000311191.6
LRCH1
leucine-rich repeats and calponin homology (CH) domain containing 1
chr2_+_196521458 0.118 ENST00000409086.3
SLC39A10
solute carrier family 39 (zinc transporter), member 10
chr16_-_4897266 0.117 ENST00000591451.1
ENST00000436648.5
ENST00000381983.3
ENST00000588297.1
ENST00000321919.9
GLYR1




glyoxylate reductase 1 homolog (Arabidopsis)




chr4_-_174451370 0.117 ENST00000359562.4
HAND2
heart and neural crest derivatives expressed 2
chr7_+_65338230 0.116 ENST00000360768.3
VKORC1L1
vitamin K epoxide reductase complex, subunit 1-like 1
chr19_+_56152262 0.116 ENST00000325333.5
ENST00000590190.1
ZNF580

zinc finger protein 580

chr4_-_89619386 0.114 ENST00000323061.5
NAP1L5
nucleosome assembly protein 1-like 5
chr7_-_144435985 0.110 ENST00000549981.1
TPK1
thiamin pyrophosphokinase 1
chr1_-_245027833 0.109 ENST00000444376.2
HNRNPU
heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
chr3_+_61547585 0.108 ENST00000295874.10
ENST00000474889.1
PTPRG

protein tyrosine phosphatase, receptor type, G

chr22_+_21771656 0.108 ENST00000407464.2
HIC2
hypermethylated in cancer 2
chr2_-_131850951 0.105 ENST00000409185.1
ENST00000389915.3
FAM168B

family with sequence similarity 168, member B

chr3_-_47823298 0.105 ENST00000254480.5
SMARCC1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr20_+_43104508 0.104 ENST00000262605.4
ENST00000372904.3
TTPAL

tocopherol (alpha) transfer protein-like

chr12_+_104850740 0.104 ENST00000547956.1
ENST00000549260.1
ENST00000303694.5
CHST11


carbohydrate (chondroitin 4) sulfotransferase 11


chr5_+_34915444 0.101 ENST00000336767.5
BRIX1
BRX1, biogenesis of ribosomes, homolog (S. cerevisiae)
chr6_+_43737939 0.100 ENST00000372067.3
VEGFA
vascular endothelial growth factor A
chr21_+_38071430 0.099 ENST00000290399.6
SIM2
single-minded family bHLH transcription factor 2
chr6_+_15246501 0.099 ENST00000341776.2
JARID2
jumonji, AT rich interactive domain 2
chr20_-_656437 0.099 ENST00000488788.2
RP5-850E9.3
Uncharacterized protein
chr19_+_16187085 0.099 ENST00000300933.4
TPM4
tropomyosin 4
chr15_+_38544476 0.098 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr7_-_105925558 0.098 ENST00000222553.3
NAMPT
nicotinamide phosphoribosyltransferase
chr5_-_168006591 0.097 ENST00000239231.6
PANK3
pantothenate kinase 3
chr20_-_17662878 0.096 ENST00000377813.1
ENST00000377807.2
ENST00000360807.4
ENST00000398782.2
RRBP1



ribosome binding protein 1



chr4_-_1857954 0.094 ENST00000302787.2
LETM1
leucine zipper-EF-hand containing transmembrane protein 1
chr3_-_178790057 0.093 ENST00000311417.2
ZMAT3
zinc finger, matrin-type 3
chr14_-_91282726 0.093 ENST00000328459.6
ENST00000357056.2
TTC7B

tetratricopeptide repeat domain 7B

chr6_+_114178512 0.092 ENST00000368635.4
MARCKS
myristoylated alanine-rich protein kinase C substrate
chr11_+_842808 0.092 ENST00000397397.2
ENST00000397411.2
ENST00000397396.1
TSPAN4


tetraspanin 4


chr8_-_9008206 0.091 ENST00000310455.3
PPP1R3B
protein phosphatase 1, regulatory subunit 3B
chr17_+_12569306 0.091 ENST00000425538.1
MYOCD
myocardin
chr1_+_26606608 0.089 ENST00000319041.6
SH3BGRL3
SH3 domain binding glutamic acid-rich protein like 3
chr1_-_78444776 0.089 ENST00000370767.1
ENST00000421641.1
FUBP1

far upstream element (FUSE) binding protein 1

chr4_+_160188889 0.089 ENST00000264431.4
RAPGEF2
Rap guanine nucleotide exchange factor (GEF) 2
chr12_-_30848914 0.089 ENST00000256079.4
IPO8
importin 8
chr11_+_46354455 0.089 ENST00000343674.6
DGKZ
diacylglycerol kinase, zeta
chr1_-_38273840 0.088 ENST00000373044.2
YRDC
yrdC N(6)-threonylcarbamoyltransferase domain containing
chr17_-_46657473 0.088 ENST00000332503.5
HOXB4
homeobox B4
chr6_-_108279369 0.087 ENST00000369002.4
SEC63
SEC63 homolog (S. cerevisiae)
chr20_-_634000 0.087 ENST00000381962.3
SRXN1
sulfiredoxin 1
chr11_+_58346584 0.087 ENST00000316059.6
ZFP91
ZFP91 zinc finger protein
chr12_+_5153085 0.086 ENST00000252321.3
KCNA5
potassium voltage-gated channel, shaker-related subfamily, member 5
chr1_+_66999799 0.086 ENST00000371035.3
ENST00000371036.3
ENST00000371037.4
SGIP1


SH3-domain GRB2-like (endophilin) interacting protein 1


chrX_+_28605516 0.085 ENST00000378993.1
IL1RAPL1
interleukin 1 receptor accessory protein-like 1
chr14_-_99737565 0.085 ENST00000357195.3
BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr12_+_104324112 0.084 ENST00000299767.5
HSP90B1
heat shock protein 90kDa beta (Grp94), member 1
chr17_+_47572647 0.084 ENST00000172229.3
NGFR
nerve growth factor receptor
chr5_+_149887672 0.083 ENST00000261797.6
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr3_-_24536253 0.082 ENST00000428492.1
ENST00000396671.2
ENST00000431815.1
ENST00000418247.1
ENST00000416420.1
ENST00000356447.4
THRB





thyroid hormone receptor, beta





chr7_+_129932974 0.082 ENST00000445470.2
ENST00000222482.4
ENST00000492072.1
ENST00000473956.1
ENST00000493259.1
ENST00000486598.1
CPA4





carboxypeptidase A4





chr11_-_31839488 0.081 ENST00000419022.1
ENST00000379132.3
ENST00000379129.2
PAX6


paired box 6


chr7_-_108096822 0.081 ENST00000379028.3
ENST00000413765.2
ENST00000379022.4
NRCAM


neuronal cell adhesion molecule


chrX_-_41782249 0.079 ENST00000442742.2
ENST00000421587.2
ENST00000378166.4
ENST00000318588.9
ENST00000361962.4
CASK




calcium/calmodulin-dependent serine protein kinase (MAGUK family)




chr1_-_200379180 0.079 ENST00000294740.3
ZNF281
zinc finger protein 281
chr21_+_39628655 0.078 ENST00000398925.1
ENST00000398928.1
ENST00000328656.4
ENST00000443341.1
KCNJ15



potassium inwardly-rectifying channel, subfamily J, member 15



chr20_-_30539773 0.078 ENST00000202017.4
PDRG1
p53 and DNA-damage regulated 1
chr1_-_39325431 0.077 ENST00000373001.3
RRAGC
Ras-related GTP binding C
chr16_+_69458428 0.077 ENST00000512062.1
ENST00000307892.8
CYB5B

cytochrome b5 type B (outer mitochondrial membrane)

chr6_+_121756809 0.076 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr1_-_1709845 0.076 ENST00000341426.5
ENST00000344463.4
NADK

NAD kinase

chr16_-_19729502 0.074 ENST00000219837.7
KNOP1
lysine-rich nucleolar protein 1
chr9_+_35749203 0.074 ENST00000456972.2
ENST00000378078.4
RGP1

RGP1 retrograde golgi transport homolog (S. cerevisiae)

chr5_+_89770696 0.073 ENST00000504930.1
ENST00000514483.1
POLR3G

polymerase (RNA) III (DNA directed) polypeptide G (32kD)

chr7_-_23053693 0.073 ENST00000409763.1
ENST00000409923.1
FAM126A

family with sequence similarity 126, member A

chr3_+_127771212 0.072 ENST00000243253.3
ENST00000481210.1
SEC61A1

Sec61 alpha 1 subunit (S. cerevisiae)

chr12_-_49351303 0.071 ENST00000256682.4
ARF3
ADP-ribosylation factor 3
chr2_-_203776864 0.071 ENST00000261015.4
WDR12
WD repeat domain 12
chr19_-_4066890 0.071 ENST00000322357.4
ZBTB7A
zinc finger and BTB domain containing 7A
chr7_-_129592700 0.071 ENST00000472396.1
ENST00000355621.3
UBE2H

ubiquitin-conjugating enzyme E2H

chr22_+_25960786 0.071 ENST00000324198.6
ADRBK2
adrenergic, beta, receptor kinase 2
chr16_+_68298405 0.070 ENST00000219343.6
ENST00000566834.1
ENST00000566454.1
SLC7A6


solute carrier family 7 (amino acid transporter light chain, y+L system), member 6


chr3_+_19988566 0.069 ENST00000273047.4
RAB5A
RAB5A, member RAS oncogene family
chr4_-_153457197 0.069 ENST00000281708.4
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr2_-_131267239 0.068 ENST00000451531.2
POTEI
POTE ankyrin domain family, member I
chr4_-_76598296 0.068 ENST00000395719.3
G3BP2
GTPase activating protein (SH3 domain) binding protein 2
chrX_+_16804544 0.068 ENST00000380122.5
ENST00000398155.4
TXLNG

taxilin gamma

chr15_+_65822756 0.068 ENST00000562901.1
ENST00000261875.5
ENST00000442729.2
ENST00000565299.1
ENST00000568793.1
PTPLAD1




protein tyrosine phosphatase-like A domain containing 1




chr1_-_211752073 0.068 ENST00000367001.4
SLC30A1
solute carrier family 30 (zinc transporter), member 1
chr16_+_4897632 0.066 ENST00000262376.6
UBN1
ubinuclein 1
chr1_-_180991978 0.065 ENST00000542060.1
ENST00000258301.5
STX6

syntaxin 6

chr7_+_32535060 0.065 ENST00000318709.4
ENST00000409301.1
ENST00000404479.1
AVL9


AVL9 homolog (S. cerevisiase)


chr4_-_110223799 0.065 ENST00000399132.1
ENST00000399126.1
ENST00000505591.1
COL25A1


collagen, type XXV, alpha 1


chr8_+_20054878 0.064 ENST00000276390.2
ENST00000519667.1
ATP6V1B2

ATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B2

chr4_-_10118469 0.064 ENST00000499869.2
WDR1
WD repeat domain 1
chr17_+_40610862 0.063 ENST00000393829.2
ENST00000546249.1
ENST00000537728.1
ENST00000264649.6
ENST00000585525.1
ENST00000343619.4
ENST00000544137.1
ENST00000589727.1
ENST00000587824.1
ATP6V0A1








ATPase, H+ transporting, lysosomal V0 subunit a1








chr7_-_123389104 0.062 ENST00000223023.4
WASL
Wiskott-Aldrich syndrome-like
chr12_+_72666407 0.062 ENST00000261180.4
TRHDE
thyrotropin-releasing hormone degrading enzyme
chr9_+_100395891 0.062 ENST00000375147.3
NCBP1
nuclear cap binding protein subunit 1, 80kDa
chr20_+_62526467 0.062 ENST00000369911.2
ENST00000360864.4
DNAJC5

DnaJ (Hsp40) homolog, subfamily C, member 5

chr6_+_157802165 0.060 ENST00000414563.2
ENST00000359775.5
ZDHHC14

zinc finger, DHHC-type containing 14

chr3_-_134093395 0.059 ENST00000249883.5
AMOTL2
angiomotin like 2
chr11_-_32452357 0.057 ENST00000379079.2
ENST00000530998.1
WT1

Wilms tumor 1

chr6_-_146135880 0.057 ENST00000237281.4
FBXO30
F-box protein 30
chr2_-_232329186 0.056 ENST00000322723.4
NCL
nucleolin
chr17_-_7120525 0.056 ENST00000447163.1
ENST00000399506.2
ENST00000302955.6
DLG4


discs, large homolog 4 (Drosophila)


chr16_+_81348528 0.056 ENST00000568107.2
GAN
gigaxonin
chr10_+_5454505 0.055 ENST00000355029.4
NET1
neuroepithelial cell transforming 1
chr17_+_2496971 0.055 ENST00000397195.5
PAFAH1B1
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa)
chr1_+_155179012 0.055 ENST00000609421.1
MTX1
metaxin 1
chr12_+_79258547 0.054 ENST00000457153.2
SYT1
synaptotagmin I
chr2_+_220299547 0.054 ENST00000312358.7
SPEG
SPEG complex locus
chr4_+_153701081 0.054 ENST00000451320.2
ENST00000429148.2
ENST00000353617.2
ENST00000405727.2
ENST00000356064.3
ARFIP1




ADP-ribosylation factor interacting protein 1




chr19_-_47975417 0.053 ENST00000236877.6
SLC8A2
solute carrier family 8 (sodium/calcium exchanger), member 2
chr7_+_28452130 0.053 ENST00000357727.2
CREB5
cAMP responsive element binding protein 5
chr19_+_46010674 0.053 ENST00000245932.6
ENST00000592139.1
ENST00000590603.1
VASP


vasodilator-stimulated phosphoprotein


chr1_-_175161890 0.053 ENST00000545251.2
ENST00000423313.1
KIAA0040

KIAA0040

chr5_+_175223313 0.053 ENST00000359546.4
CPLX2
complexin 2
chr3_+_51575596 0.053 ENST00000409535.2
RAD54L2
RAD54-like 2 (S. cerevisiae)
chrX_+_110339439 0.053 ENST00000372010.1
ENST00000519681.1
ENST00000372007.5
PAK3


p21 protein (Cdc42/Rac)-activated kinase 3


chr14_+_68086515 0.052 ENST00000261783.3
ARG2
arginase 2
chr5_+_125935960 0.052 ENST00000297540.4
PHAX
phosphorylated adaptor for RNA export
chr8_+_91803695 0.052 ENST00000417640.2
NECAB1
N-terminal EF-hand calcium binding protein 1
chr19_-_15311713 0.052 ENST00000601011.1
ENST00000263388.2
NOTCH3

notch 3

chr20_-_45984401 0.052 ENST00000311275.7
ZMYND8
zinc finger, MYND-type containing 8
chr15_+_31619013 0.051 ENST00000307145.3
KLF13
Kruppel-like factor 13
chr20_+_42875887 0.051 ENST00000342560.5
GDAP1L1
ganglioside induced differentiation associated protein 1-like 1
chr2_+_191745560 0.051 ENST00000338435.4
GLS
glutaminase
chr11_+_46639071 0.050 ENST00000580238.1
ENST00000581416.1
ENST00000529655.1
ENST00000533325.1
ENST00000581438.1
ENST00000583249.1
ENST00000530500.1
ENST00000526508.1
ENST00000578626.1
ENST00000577256.1
ENST00000524625.1
ENST00000582547.1
ENST00000359513.4
ENST00000528494.1
ATG13













autophagy related 13













chr1_-_154600421 0.049 ENST00000368471.3
ENST00000292205.5
ADAR

adenosine deaminase, RNA-specific

chr2_+_69969106 0.049 ENST00000409920.1
ENST00000394295.4
ENST00000536030.1
ANXA4


annexin A4


chr1_+_167691191 0.049 ENST00000392121.3
ENST00000474859.1
MPZL1

myelin protein zero-like 1

chrX_-_48814810 0.048 ENST00000376488.3
ENST00000396743.3
ENST00000156084.4
OTUD5


OTU domain containing 5


chr3_+_39093481 0.048 ENST00000302313.5
ENST00000544962.1
ENST00000396258.3
ENST00000418020.1
WDR48



WD repeat domain 48



chr18_-_70535177 0.047 ENST00000327305.6
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr10_+_93558069 0.047 ENST00000371627.4
TNKS2
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr11_-_124670550 0.047 ENST00000239614.4
MSANTD2
Myb/SANT-like DNA-binding domain containing 2
chr11_-_76091986 0.046 ENST00000260045.3
PRKRIR
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr11_-_65769594 0.046 ENST00000532707.1
ENST00000533544.1
ENST00000526451.1
ENST00000312234.2
ENST00000530462.1
ENST00000525767.1
ENST00000529964.1
ENST00000527249.1
EIF1AD







eukaryotic translation initiation factor 1A domain containing







chr15_+_76629064 0.046 ENST00000290759.4
ISL2
ISL LIM homeobox 2
chr1_-_154155595 0.046 ENST00000328159.4
ENST00000368531.2
ENST00000323144.7
ENST00000368533.3
ENST00000341372.3
TPM3




tropomyosin 3




chr11_+_128563652 0.046 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr2_+_178077477 0.046 ENST00000411529.2
ENST00000435711.1
HNRNPA3

heterogeneous nuclear ribonucleoprotein A3

chr10_+_101419187 0.045 ENST00000370489.4
ENTPD7
ectonucleoside triphosphate diphosphohydrolase 7
chr16_+_69599861 0.045 ENST00000354436.2
NFAT5
nuclear factor of activated T-cells 5, tonicity-responsive
chr2_-_9563319 0.045 ENST00000497105.1
ENST00000360635.3
ENST00000359712.3
ITGB1BP1


integrin beta 1 binding protein 1


chr2_+_60983361 0.045 ENST00000238714.3
PAPOLG
poly(A) polymerase gamma
chr3_-_186080012 0.044 ENST00000544847.1
ENST00000265022.3
DGKG

diacylglycerol kinase, gamma 90kDa

chr4_-_99851766 0.044 ENST00000450253.2
EIF4E
eukaryotic translation initiation factor 4E
chr4_-_22517620 0.044 ENST00000502482.1
ENST00000334304.5
GPR125

G protein-coupled receptor 125

chr6_-_86352642 0.044 ENST00000355238.6
SYNCRIP
synaptotagmin binding, cytoplasmic RNA interacting protein
chr2_+_200775971 0.043 ENST00000319974.5
C2orf69
chromosome 2 open reading frame 69
chr9_-_107690420 0.042 ENST00000423487.2
ENST00000374733.1
ENST00000374736.3
ABCA1


ATP-binding cassette, sub-family A (ABC1), member 1


chr13_+_42846272 0.042 ENST00000025301.2
AKAP11
A kinase (PRKA) anchor protein 11
chr17_-_56084578 0.042 ENST00000582730.2
ENST00000584773.1
ENST00000585096.1
ENST00000258962.4
SRSF1



serine/arginine-rich splicing factor 1



chr8_+_59465728 0.041 ENST00000260130.4
ENST00000422546.2
ENST00000447182.2
ENST00000413219.2
ENST00000424270.2
ENST00000523483.1
ENST00000520168.1
SDCBP






syndecan binding protein (syntenin)






chr5_+_74632993 0.041 ENST00000287936.4
HMGCR
3-hydroxy-3-methylglutaryl-CoA reductase
chr17_-_10741762 0.041 ENST00000580256.2
PIRT
phosphoinositide-interacting regulator of transient receptor potential channels
chr3_-_42846021 0.041 ENST00000321331.7
HIGD1A
HIG1 hypoxia inducible domain family, member 1A
chr15_-_71407806 0.040 ENST00000566432.1
ENST00000567117.1
CT62

cancer/testis antigen 62

chr3_+_113465866 0.040 ENST00000273398.3
ENST00000538620.1
ENST00000496747.1
ENST00000475322.1
ATP6V1A



ATPase, H+ transporting, lysosomal 70kDa, V1 subunit A



chr1_+_183441600 0.040 ENST00000367537.3
SMG7
SMG7 nonsense mediated mRNA decay factor
chr12_-_46766577 0.039 ENST00000256689.5
SLC38A2
solute carrier family 38, member 2
chr7_+_5229819 0.039 ENST00000288828.4
ENST00000401525.3
ENST00000404704.3
WIPI2


WD repeat domain, phosphoinositide interacting 2


chr11_+_34073195 0.038 ENST00000341394.4
CAPRIN1
cell cycle associated protein 1
chr8_-_101965146 0.038 ENST00000395957.2
ENST00000395948.2
ENST00000457309.1
YWHAZ


tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0046495 nicotinamide riboside catabolic process(GO:0006738) nicotinamide riboside metabolic process(GO:0046495) pyridine nucleoside metabolic process(GO:0070637) pyridine nucleoside catabolic process(GO:0070638)
0.1 0.2 GO:2000646 positive regulation of receptor catabolic process(GO:2000646)
0.1 0.2 GO:0002605 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of dendritic cell antigen processing and presentation(GO:0002605)
0.1 0.6 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.2 GO:0060516 primary prostatic bud elongation(GO:0060516) renal vesicle induction(GO:0072034)
0.1 0.2 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 0.2 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.2 GO:0070563 negative regulation of vitamin D receptor signaling pathway(GO:0070563)
0.1 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.1 0.2 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.2 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.0 0.1 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.0 0.1 GO:1904956 neural crest cell fate commitment(GO:0014034) regulation of midbrain dopaminergic neuron differentiation(GO:1904956) regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000053)
0.0 0.2 GO:1902378 vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040)
0.0 0.4 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.2 GO:0061032 visceral serous pericardium development(GO:0061032)
0.0 0.3 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:1902336 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336) regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.0 0.2 GO:1904381 Golgi apparatus mannose trimming(GO:1904381)
0.0 0.1 GO:1900222 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.1 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:0031247 actin rod assembly(GO:0031247)
0.0 0.1 GO:0042357 thiamine diphosphate metabolic process(GO:0042357)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.1 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.2 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.1 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.0 0.6 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.1 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:1900425 negative regulation of defense response to bacterium(GO:1900425)
0.0 0.2 GO:0030578 PML body organization(GO:0030578)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.2 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.1 GO:0098746 fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746)
0.0 0.1 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.0 0.1 GO:0003322 pancreatic A cell development(GO:0003322)
0.0 0.1 GO:0042247 morphogenesis of follicular epithelium(GO:0016333) establishment or maintenance of polarity of follicular epithelium(GO:0016334) establishment of planar polarity of follicular epithelium(GO:0042247)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.1 GO:1903385 regulation of homophilic cell adhesion(GO:1903385)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.1 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.1 GO:0006408 snRNA export from nucleus(GO:0006408)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.0 GO:2000669 negative regulation of dendritic cell apoptotic process(GO:2000669)
0.0 0.1 GO:0006477 protein sulfation(GO:0006477)
0.0 0.1 GO:0070141 response to UV-A(GO:0070141)
0.0 0.0 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.0 GO:1901873 regulation of post-translational protein modification(GO:1901873)
0.0 0.1 GO:0060372 regulation of atrial cardiac muscle cell membrane repolarization(GO:0060372)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.0 GO:0015917 aminophospholipid transport(GO:0015917) regulation of high-density lipoprotein particle assembly(GO:0090107)
0.0 0.2 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.4 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0005846 nuclear cap binding complex(GO:0005846)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.1 GO:0060200 clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.1 GO:0042643 actomyosin, actin portion(GO:0042643)
0.0 0.2 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0070545 PeBoW complex(GO:0070545)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.1 0.2 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.1 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.0 0.3 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.2 GO:0016215 stearoyl-CoA 9-desaturase activity(GO:0004768) acyl-CoA desaturase activity(GO:0016215)
0.0 0.1 GO:0051139 metal ion:proton antiporter activity(GO:0051139)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.1 GO:0004514 nicotinate-nucleotide diphosphorylase (carboxylating) activity(GO:0004514)
0.0 0.1 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.2 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.1 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0034188 apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.0 0.0 GO:0005137 interleukin-5 receptor binding(GO:0005137)
0.0 0.1 GO:0016778 diphosphotransferase activity(GO:0016778)
0.0 0.2 GO:0031957 fatty acid transporter activity(GO:0015245) very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.0 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.0 GO:0008192 RNA guanylyltransferase activity(GO:0008192)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID_VEGF_VEGFR_PATHWAY VEGF and VEGFR signaling network
0.0 0.8 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.0 1.0 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.3 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs