Motif ID: GGCAGUG

Z-value: 0.851


Mature miRNA associated with seed GGCAGUG:

NamemiRBase Accession
hsa-miR-34a-5p MIMAT0000255
hsa-miR-34c-5p MIMAT0000686
hsa-miR-449a MIMAT0001541
hsa-miR-449b-5p MIMAT0003327



Activity profile for motif GGCAGUG.

activity profile for motif GGCAGUG


Sorted Z-values histogram for motif GGCAGUG

Sorted Z-values for motif GGCAGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of GGCAGUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_100770328 2.731 ENST00000223095.4
ENST00000445463.2
SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

chr19_+_54371114 1.571 ENST00000448420.1
ENST00000439000.1
ENST00000391770.4
ENST00000391771.1
MYADM



myeloid-associated differentiation marker



chr2_+_48541776 1.399 ENST00000413569.1
ENST00000340553.3
FOXN2

forkhead box N2

chr12_-_95044309 1.335 ENST00000261226.4
TMCC3
transmembrane and coiled-coil domain family 3
chr19_-_50143452 1.306 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr17_-_41174424 1.097 ENST00000355653.3
VAT1
vesicle amine transport 1
chr19_+_41725088 1.071 ENST00000301178.4
AXL
AXL receptor tyrosine kinase
chr19_-_2783363 1.038 ENST00000221566.2
SGTA
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr7_+_145813453 1.024 ENST00000361727.3
CNTNAP2
contactin associated protein-like 2
chr19_-_49015050 0.876 ENST00000600059.1
LMTK3
lemur tyrosine kinase 3
chr4_+_75480629 0.852 ENST00000380846.3
AREGB
amphiregulin B
chr12_+_107712173 0.844 ENST00000280758.5
ENST00000420571.2
BTBD11

BTB (POZ) domain containing 11

chr9_-_123639600 0.818 ENST00000373896.3
PHF19
PHD finger protein 19
chr4_+_99182593 0.803 ENST00000508213.1
ENST00000408927.3
ENST00000514122.1
ENST00000453712.2
ENST00000511212.1
ENST00000408900.3
ENST00000339360.5
RAP1GDS1






RAP1, GTP-GDP dissociation stimulator 1






chr16_-_4588822 0.778 ENST00000564828.1
CDIP1
cell death-inducing p53 target 1
chr17_+_61086917 0.778 ENST00000424789.2
ENST00000389520.4
TANC2

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2

chr1_+_84543734 0.770 ENST00000370689.2
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr12_+_1800179 0.756 ENST00000357103.4
ADIPOR2
adiponectin receptor 2
chr9_+_131102925 0.733 ENST00000372870.1
ENST00000300456.4
SLC27A4

solute carrier family 27 (fatty acid transporter), member 4

chr11_-_119599794 0.733 ENST00000264025.3
PVRL1
poliovirus receptor-related 1 (herpesvirus entry mediator C)
chr2_-_208030647 0.722 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr8_+_11141925 0.713 ENST00000221086.3
MTMR9
myotubularin related protein 9
chr15_+_90744533 0.677 ENST00000411539.2
SEMA4B
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr20_-_10654639 0.665 ENST00000254958.5
JAG1
jagged 1
chr1_+_165796753 0.655 ENST00000367879.4
UCK2
uridine-cytidine kinase 2
chr5_+_149887672 0.632 ENST00000261797.6
NDST1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr6_-_75915757 0.629 ENST00000322507.8
COL12A1
collagen, type XII, alpha 1
chr2_-_220094294 0.620 ENST00000436856.1
ENST00000428226.1
ENST00000409422.1
ENST00000431715.1
ENST00000457841.1
ENST00000439812.1
ENST00000361242.4
ENST00000396761.2
ATG9A







autophagy related 9A







chr14_-_99737565 0.611 ENST00000357195.3
BCL11B
B-cell CLL/lymphoma 11B (zinc finger protein)
chr2_-_122042770 0.601 ENST00000263707.5
TFCP2L1
transcription factor CP2-like 1
chr22_+_51112800 0.600 ENST00000414786.2
SHANK3
SH3 and multiple ankyrin repeat domains 3
chr7_-_92463210 0.598 ENST00000265734.4
CDK6
cyclin-dependent kinase 6
chr17_-_71640227 0.587 ENST00000388726.3
ENST00000392650.3
SDK2

sidekick cell adhesion molecule 2

chr14_-_68162464 0.586 ENST00000553384.1
ENST00000557726.1
ENST00000381346.4
RDH11


retinol dehydrogenase 11 (all-trans/9-cis/11-cis)


chr11_+_117049445 0.578 ENST00000324225.4
ENST00000532960.1
SIDT2

SID1 transmembrane family, member 2

chr11_+_60681346 0.573 ENST00000227525.3
TMEM109
transmembrane protein 109
chr9_+_124413873 0.573 ENST00000408936.3
DAB2IP
DAB2 interacting protein
chr19_-_14629224 0.569 ENST00000254322.2
DNAJB1
DnaJ (Hsp40) homolog, subfamily B, member 1
chr1_+_178694300 0.566 ENST00000367635.3
RALGPS2
Ral GEF with PH domain and SH3 binding motif 2
chr15_+_66679155 0.561 ENST00000307102.5
MAP2K1
mitogen-activated protein kinase kinase 1
chr19_+_7895074 0.561 ENST00000270530.4
EVI5L
ecotropic viral integration site 5-like
chr12_+_107168342 0.548 ENST00000392837.4
RIC8B
RIC8 guanine nucleotide exchange factor B
chr10_+_75936444 0.531 ENST00000372734.3
ENST00000541550.1
ADK

adenosine kinase

chr2_+_24272543 0.530 ENST00000380991.4
FKBP1B
FK506 binding protein 1B, 12.6 kDa
chr2_+_74881355 0.524 ENST00000357877.2
SEMA4F
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4F
chr8_+_42752053 0.523 ENST00000307602.4
HOOK3
hook microtubule-tethering protein 3
chr12_-_109125285 0.520 ENST00000552871.1
ENST00000261401.3
CORO1C

coronin, actin binding protein, 1C

chr1_+_31769836 0.493 ENST00000344147.5
ENST00000373714.1
ENST00000546109.1
ENST00000422613.2
ZCCHC17



zinc finger, CCHC domain containing 17



chr15_-_42264702 0.467 ENST00000220325.4
EHD4
EH-domain containing 4
chr22_-_37099555 0.467 ENST00000300105.6
CACNG2
calcium channel, voltage-dependent, gamma subunit 2
chr22_-_36784035 0.467 ENST00000216181.5
MYH9
myosin, heavy chain 9, non-muscle
chr6_+_46620676 0.458 ENST00000371347.5
ENST00000411689.2
SLC25A27

solute carrier family 25, member 27

chr3_-_48229846 0.449 ENST00000302506.3
ENST00000351231.3
ENST00000437972.1
CDC25A


cell division cycle 25A


chr19_-_46296011 0.449 ENST00000377735.3
ENST00000270223.6
DMWD

dystrophia myotonica, WD repeat containing

chr5_-_150948414 0.447 ENST00000261800.5
FAT2
FAT atypical cadherin 2
chr8_-_60031762 0.443 ENST00000361421.1
TOX
thymocyte selection-associated high mobility group box
chr8_+_102504651 0.440 ENST00000251808.3
ENST00000521085.1
GRHL2

grainyhead-like 2 (Drosophila)

chr10_+_105036909 0.438 ENST00000369849.4
INA
internexin neuronal intermediate filament protein, alpha
chr5_+_172261228 0.438 ENST00000393784.3
ERGIC1
endoplasmic reticulum-golgi intermediate compartment (ERGIC) 1
chr1_-_39325431 0.433 ENST00000373001.3
RRAGC
Ras-related GTP binding C
chr11_+_65405556 0.429 ENST00000534313.1
ENST00000533361.1
ENST00000526137.1
SIPA1


signal-induced proliferation-associated 1


chr2_+_45168875 0.428 ENST00000260653.3
SIX3
SIX homeobox 3
chr15_+_91473403 0.426 ENST00000394275.2
UNC45A
unc-45 homolog A (C. elegans)
chr3_-_172428959 0.426 ENST00000475381.1
ENST00000538775.1
ENST00000273512.3
ENST00000543711.1
NCEH1



neutral cholesterol ester hydrolase 1



chr5_+_175223313 0.423 ENST00000359546.4
CPLX2
complexin 2
chr11_-_65667884 0.420 ENST00000448083.2
ENST00000531493.1
ENST00000532401.1
FOSL1


FOS-like antigen 1


chr14_-_64194745 0.420 ENST00000247225.6
SGPP1
sphingosine-1-phosphate phosphatase 1
chr1_+_11994715 0.417 ENST00000449038.1
ENST00000376369.3
ENST00000429000.2
ENST00000196061.4
PLOD1



procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1



chr9_-_136242909 0.405 ENST00000371991.3
ENST00000545297.1
SURF4

surfeit 4

chr10_+_99205959 0.396 ENST00000352634.4
ENST00000353979.3
ENST00000370842.2
ENST00000345745.5
ZDHHC16



zinc finger, DHHC-type containing 16



chr2_-_166930131 0.394 ENST00000303395.4
ENST00000409050.1
ENST00000423058.2
ENST00000375405.3
SCN1A



sodium channel, voltage-gated, type I, alpha subunit



chr19_-_41196534 0.389 ENST00000252891.4
NUMBL
numb homolog (Drosophila)-like
chr20_+_62371206 0.386 ENST00000266077.2
SLC2A4RG
SLC2A4 regulator
chr10_-_71930222 0.385 ENST00000458634.2
ENST00000373239.2
ENST00000373242.2
ENST00000373241.4
SAR1A



SAR1 homolog A (S. cerevisiae)



chr7_+_128864848 0.376 ENST00000325006.3
ENST00000446544.2
AHCYL2

adenosylhomocysteinase-like 2

chr19_-_2456922 0.369 ENST00000582871.1
ENST00000325327.3
LMNB2

lamin B2

chr9_-_139440314 0.369 ENST00000277541.6
NOTCH1
notch 1
chr3_-_113465065 0.364 ENST00000497255.1
ENST00000478020.1
ENST00000240922.3
ENST00000493900.1
NAA50



N(alpha)-acetyltransferase 50, NatE catalytic subunit



chr3_+_25469724 0.362 ENST00000437042.2
RARB
retinoic acid receptor, beta
chr15_+_71389281 0.361 ENST00000355327.3
THSD4
thrombospondin, type I, domain containing 4
chr5_-_132299313 0.358 ENST00000265343.5
AFF4
AF4/FMR2 family, member 4
chr13_-_25746416 0.348 ENST00000515384.1
ENST00000357816.2
AMER2

APC membrane recruitment protein 2

chr1_+_205012293 0.348 ENST00000331830.4
CNTN2
contactin 2 (axonal)
chr3_+_171758344 0.335 ENST00000336824.4
ENST00000423424.1
FNDC3B

fibronectin type III domain containing 3B

chr9_-_110251836 0.328 ENST00000374672.4
KLF4
Kruppel-like factor 4 (gut)
chr3_-_176914238 0.326 ENST00000430069.1
ENST00000428970.1
TBL1XR1

transducin (beta)-like 1 X-linked receptor 1

chr11_+_69455855 0.324 ENST00000227507.2
ENST00000536559.1
CCND1

cyclin D1

chr22_-_38669030 0.321 ENST00000361906.3
TMEM184B
transmembrane protein 184B
chr6_-_110500905 0.320 ENST00000392587.2
WASF1
WAS protein family, member 1
chr11_+_64126614 0.314 ENST00000528057.1
ENST00000334205.4
ENST00000294261.4
RPS6KA4


ribosomal protein S6 kinase, 90kDa, polypeptide 4


chr1_-_21978312 0.313 ENST00000359708.4
ENST00000290101.4
RAP1GAP

RAP1 GTPase activating protein

chr12_-_95611149 0.307 ENST00000549499.1
ENST00000343958.4
ENST00000546711.1
FGD6


FYVE, RhoGEF and PH domain containing 6


chr5_+_176560742 0.297 ENST00000439151.2
NSD1
nuclear receptor binding SET domain protein 1
chr5_+_133861790 0.291 ENST00000395003.1
PHF15
jade family PHD finger 2
chr11_+_65837907 0.290 ENST00000320580.4
PACS1
phosphofurin acidic cluster sorting protein 1
chr4_+_113970772 0.287 ENST00000504454.1
ENST00000394537.3
ENST00000357077.4
ENST00000264366.6
ANK2



ankyrin 2, neuronal



chr15_-_44486632 0.280 ENST00000484674.1
FRMD5
FERM domain containing 5
chr6_-_43543702 0.277 ENST00000265351.7
XPO5
exportin 5
chr9_-_101471479 0.275 ENST00000259455.2
GABBR2
gamma-aminobutyric acid (GABA) B receptor, 2
chr4_-_109089573 0.272 ENST00000265165.1
LEF1
lymphoid enhancer-binding factor 1
chr17_+_1646130 0.272 ENST00000453066.1
ENST00000324015.3
ENST00000450523.2
ENST00000453723.1
ENST00000382061.4
SERPINF2




serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 2




chr15_+_79724858 0.271 ENST00000305428.3
KIAA1024
KIAA1024
chr10_-_104262426 0.270 ENST00000487599.1
ACTR1A
ARP1 actin-related protein 1 homolog A, centractin alpha (yeast)
chr2_-_163695128 0.270 ENST00000332142.5
KCNH7
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr11_-_2906979 0.269 ENST00000380725.1
ENST00000313407.6
ENST00000430149.2
ENST00000440480.2
ENST00000414822.3
CDKN1C




cyclin-dependent kinase inhibitor 1C (p57, Kip2)




chr17_-_31620006 0.265 ENST00000225823.2
ASIC2
acid-sensing (proton-gated) ion channel 2
chr17_-_61777459 0.261 ENST00000578993.1
ENST00000583211.1
ENST00000259006.3
LIMD2


LIM domain containing 2


chr8_-_4852218 0.258 ENST00000400186.3
ENST00000602723.1
CSMD1

CUB and Sushi multiple domains 1

chr11_+_18416133 0.257 ENST00000227157.4
ENST00000478970.2
ENST00000495052.1
LDHA


lactate dehydrogenase A


chr19_-_10514184 0.257 ENST00000589629.1
ENST00000222005.2
CDC37

cell division cycle 37

chr4_-_114900831 0.256 ENST00000315366.7
ARSJ
arylsulfatase family, member J
chr15_+_38544476 0.255 ENST00000299084.4
SPRED1
sprouty-related, EVH1 domain containing 1
chr17_+_43971643 0.255 ENST00000344290.5
ENST00000262410.5
ENST00000351559.5
ENST00000340799.5
ENST00000535772.1
ENST00000347967.5
MAPT





microtubule-associated protein tau





chr11_-_67236691 0.255 ENST00000544903.1
ENST00000308022.2
ENST00000393877.3
ENST00000452789.2
TMEM134



transmembrane protein 134



chr17_-_27224621 0.255 ENST00000394906.2
ENST00000585169.1
ENST00000394908.4
FLOT2


flotillin 2


chr11_-_64410787 0.250 ENST00000301894.2
NRXN2
neurexin 2
chr16_+_81069433 0.247 ENST00000299575.4
ATMIN
ATM interactor
chr9_+_103204553 0.245 ENST00000334943.6
ENST00000502978.1
TMEFF1
MSANTD3-TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
MSANTD3-TMEFF1 readthrough
chr6_+_96463840 0.244 ENST00000302103.5
FUT9
fucosyltransferase 9 (alpha (1,3) fucosyltransferase)
chr3_-_27498235 0.243 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7


solute carrier family 4, sodium bicarbonate cotransporter, member 7


chr3_+_39851094 0.240 ENST00000302541.6
MYRIP
myosin VIIA and Rab interacting protein
chr9_-_104249319 0.239 ENST00000374847.1
TMEM246
transmembrane protein 246
chr12_-_57030115 0.236 ENST00000379441.3
ENST00000179765.5
ENST00000551812.1
BAZ2A


bromodomain adjacent to zinc finger domain, 2A


chr1_-_156542328 0.233 ENST00000361170.2
IQGAP3
IQ motif containing GTPase activating protein 3
chr4_+_55095264 0.233 ENST00000257290.5
PDGFRA
platelet-derived growth factor receptor, alpha polypeptide
chr12_-_27167233 0.233 ENST00000535819.1
ENST00000543803.1
ENST00000535423.1
ENST00000539741.1
ENST00000343028.4
ENST00000545600.1
ENST00000543088.1
TM7SF3






transmembrane 7 superfamily member 3






chr11_-_46722117 0.232 ENST00000311956.4
ARHGAP1
Rho GTPase activating protein 1
chr8_+_28174649 0.230 ENST00000301908.3
PNOC
prepronociceptin
chr1_+_160175117 0.226 ENST00000360472.4
PEA15
phosphoprotein enriched in astrocytes 15
chr10_+_71078595 0.223 ENST00000359426.6
HK1
hexokinase 1
chr16_+_56225248 0.222 ENST00000262493.6
GNAO1
guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O
chr4_+_144257915 0.220 ENST00000262995.4
GAB1
GRB2-associated binding protein 1
chr17_-_8066250 0.218 ENST00000488857.1
ENST00000481878.1
ENST00000316509.6
ENST00000498285.1
VAMP2


RP11-599B13.6
vesicle-associated membrane protein 2 (synaptobrevin 2)


Uncharacterized protein
chr10_+_82213904 0.218 ENST00000429989.3
TSPAN14
tetraspanin 14
chr2_-_97405775 0.216 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
LMAN2L




lectin, mannose-binding 2-like




chr11_-_9025541 0.215 ENST00000525100.1
ENST00000309166.3
ENST00000531090.1
NRIP3


nuclear receptor interacting protein 3


chr18_-_65184217 0.209 ENST00000310045.7
DSEL
dermatan sulfate epimerase-like
chr4_+_124320665 0.208 ENST00000394339.2
SPRY1
sprouty homolog 1, antagonist of FGF signaling (Drosophila)
chrX_-_18372792 0.206 ENST00000251900.4
SCML2
sex comb on midleg-like 2 (Drosophila)
chr1_+_197881592 0.205 ENST00000367391.1
ENST00000367390.3
LHX9

LIM homeobox 9

chr8_-_66754172 0.205 ENST00000401827.3
PDE7A
phosphodiesterase 7A
chr19_+_18794470 0.204 ENST00000321949.8
ENST00000338797.6
CRTC1

CREB regulated transcription coactivator 1

chr12_-_49504655 0.201 ENST00000551782.1
ENST00000267102.8
LMBR1L

limb development membrane protein 1-like

chr18_+_67068228 0.200 ENST00000382713.5
DOK6
docking protein 6
chr10_-_15210666 0.199 ENST00000378165.4
NMT2
N-myristoyltransferase 2
chr9_+_103235365 0.197 ENST00000374879.4
TMEFF1
transmembrane protein with EGF-like and two follistatin-like domains 1
chr22_+_29469012 0.197 ENST00000400335.4
ENST00000400338.2
KREMEN1

kringle containing transmembrane protein 1

chr8_-_82024290 0.196 ENST00000220597.4
PAG1
phosphoprotein associated with glycosphingolipid microdomains 1
chr11_-_64901978 0.196 ENST00000294256.8
ENST00000377190.3
SYVN1

synovial apoptosis inhibitor 1, synoviolin

chr1_-_226374373 0.193 ENST00000366812.5
ACBD3
acyl-CoA binding domain containing 3
chr1_+_231297798 0.193 ENST00000444294.3
TRIM67
tripartite motif containing 67
chr1_+_64058939 0.193 ENST00000371084.3
PGM1
phosphoglucomutase 1
chr7_+_138916231 0.190 ENST00000473989.3
ENST00000288561.8
UBN2

ubinuclein 2

chr17_-_4269768 0.188 ENST00000396981.2
UBE2G1
ubiquitin-conjugating enzyme E2G 1
chr17_+_28705921 0.187 ENST00000225719.4
CPD
carboxypeptidase D
chr8_-_11324273 0.187 ENST00000284486.4
FAM167A
family with sequence similarity 167, member A
chr11_+_74660278 0.186 ENST00000263672.6
ENST00000530257.1
ENST00000526361.1
ENST00000532972.1
SPCS2



signal peptidase complex subunit 2 homolog (S. cerevisiae)



chrX_+_154997474 0.180 ENST00000302805.2
SPRY3
sprouty homolog 3 (Drosophila)
chr3_+_38206975 0.180 ENST00000446845.1
ENST00000311806.3
OXSR1

oxidative stress responsive 1

chr11_+_66025167 0.179 ENST00000394067.2
ENST00000316924.5
ENST00000421552.1
ENST00000394078.1
KLC2



kinesin light chain 2



chr3_-_179754706 0.179 ENST00000465751.1
ENST00000467460.1
PEX5L

peroxisomal biogenesis factor 5-like

chr1_-_161014731 0.178 ENST00000368020.1
USF1
upstream transcription factor 1
chr3_-_184870751 0.175 ENST00000335012.2
C3orf70
chromosome 3 open reading frame 70
chr11_+_46354455 0.175 ENST00000343674.6
DGKZ
diacylglycerol kinase, zeta
chr10_-_135238076 0.170 ENST00000414069.2
SPRN
shadow of prion protein homolog (zebrafish)
chr1_+_155247207 0.169 ENST00000368358.3
HCN3
hyperpolarization activated cyclic nucleotide-gated potassium channel 3
chr15_-_52861394 0.168 ENST00000563277.1
ENST00000566423.1
ARPP19

cAMP-regulated phosphoprotein, 19kDa

chr6_+_21593972 0.167 ENST00000244745.1
ENST00000543472.1
SOX4

SRY (sex determining region Y)-box 4

chr12_+_20522179 0.166 ENST00000359062.3
PDE3A
phosphodiesterase 3A, cGMP-inhibited
chr2_+_43864387 0.165 ENST00000282406.4
PLEKHH2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chrX_+_118108571 0.165 ENST00000304778.7
LONRF3
LON peptidase N-terminal domain and ring finger 3
chr7_-_143059845 0.164 ENST00000443739.2
FAM131B
family with sequence similarity 131, member B
chr13_-_27334879 0.162 ENST00000405846.3
GPR12
G protein-coupled receptor 12
chr21_+_45138941 0.162 ENST00000398081.1
ENST00000468090.1
ENST00000291565.4
PDXK


pyridoxal (pyridoxine, vitamin B6) kinase


chr20_+_39765581 0.161 ENST00000244007.3
PLCG1
phospholipase C, gamma 1
chr1_+_151171012 0.160 ENST00000349792.5
ENST00000409426.1
ENST00000441902.2
ENST00000368890.4
ENST00000424999.1
ENST00000368888.4
PIP5K1A





phosphatidylinositol-4-phosphate 5-kinase, type I, alpha





chr2_+_239335449 0.155 ENST00000264607.4
ASB1
ankyrin repeat and SOCS box containing 1
chr9_+_115513003 0.154 ENST00000374232.3
SNX30
sorting nexin family member 30
chr11_-_118047376 0.153 ENST00000278947.5
SCN2B
sodium channel, voltage-gated, type II, beta subunit
chr7_+_2443202 0.152 ENST00000258711.6
CHST12
carbohydrate (chondroitin 4) sulfotransferase 12
chr15_-_67546963 0.152 ENST00000561452.1
ENST00000261880.5
AAGAB

alpha- and gamma-adaptin binding protein

chr2_-_47168906 0.151 ENST00000444761.2
ENST00000409147.1
MCFD2

multiple coagulation factor deficiency 2

chr2_-_100721178 0.149 ENST00000409236.2
AFF3
AF4/FMR2 family, member 3
chr16_-_89007491 0.147 ENST00000327483.5
ENST00000564416.1
CBFA2T3

core-binding factor, runt domain, alpha subunit 2; translocated to, 3

chr14_+_100705322 0.146 ENST00000262238.4
YY1
YY1 transcription factor
chr4_-_175750364 0.146 ENST00000340217.5
ENST00000274093.3
GLRA3

glycine receptor, alpha 3

chr18_-_60987220 0.144 ENST00000398117.1
BCL2
B-cell CLL/lymphoma 2
chr3_+_50712672 0.143 ENST00000266037.9
DOCK3
dedicator of cytokinesis 3
chr3_-_128879875 0.142 ENST00000393292.3
ENST00000273541.8
ENST00000418265.1
ISY1

ISY1-RAB43
ISY1 splicing factor homolog (S. cerevisiae)

ISY1-RAB43 readthrough
chr7_-_73133959 0.140 ENST00000395155.3
ENST00000395154.3
ENST00000222812.3
ENST00000395156.3
STX1A



syntaxin 1A (brain)



chr12_+_112563335 0.140 ENST00000549358.1
ENST00000257604.5
ENST00000548092.1
ENST00000552896.1
TRAFD1



TRAF-type zinc finger domain containing 1



chr2_+_120517174 0.139 ENST00000263708.2
PTPN4
protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
chr6_-_82462425 0.139 ENST00000369754.3
ENST00000320172.6
ENST00000369756.3
FAM46A


family with sequence similarity 46, member A


chr12_+_27396901 0.138 ENST00000541191.1
ENST00000389032.3
STK38L

serine/threonine kinase 38 like

chrX_-_118284542 0.138 ENST00000402510.2
KIAA1210
KIAA1210
chr18_+_55018044 0.137 ENST00000324000.3
ST8SIA3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr14_+_23299088 0.136 ENST00000355151.5
ENST00000397496.3
ENST00000555345.1
ENST00000432849.3
ENST00000553711.1
ENST00000556465.1
ENST00000397505.2
ENST00000557221.1
ENST00000311892.6
ENST00000556840.1
ENST00000555536.1
MRPL52










mitochondrial ribosomal protein L52










chr16_+_30960375 0.135 ENST00000318663.4
ENST00000566237.1
ENST00000562699.1
ORAI3


ORAI calcium release-activated calcium modulator 3


chr1_+_112938803 0.135 ENST00000271277.6
CTTNBP2NL
CTTNBP2 N-terminal like
chr16_+_69345243 0.134 ENST00000254950.11
VPS4A
vacuolar protein sorting 4 homolog A (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:2000097 chronological cell aging(GO:0001300) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.4 1.6 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.3 1.0 GO:0071109 superior temporal gyrus development(GO:0071109)
0.3 0.9 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.3 0.3 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.2 1.2 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.2 0.7 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 1.1 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.2 0.5 GO:0044209 AMP salvage(GO:0044209)
0.2 0.7 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.2 0.6 GO:0044805 late nucleophagy(GO:0044805)
0.2 1.1 GO:2000669 positive regulation of pinocytosis(GO:0048549) negative regulation of dendritic cell apoptotic process(GO:2000669)
0.1 0.4 GO:0009946 proximal/distal axis specification(GO:0009946) neuroblast differentiation(GO:0014016)
0.1 0.4 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.4 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.4 GO:2000974 atrioventricular node development(GO:0003162) mitral valve formation(GO:0003192) cardiac right atrium morphogenesis(GO:0003213) negative regulation of pro-B cell differentiation(GO:2000974)
0.1 0.3 GO:0031133 regulation of axon diameter(GO:0031133)
0.1 0.6 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324) negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.5 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.1 0.8 GO:0097338 response to clozapine(GO:0097338)
0.1 0.3 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.4 GO:0006668 sphinganine-1-phosphate metabolic process(GO:0006668)
0.1 0.3 GO:1903697 negative regulation of microvillus assembly(GO:1903697)
0.1 0.3 GO:0098907 protein localization to M-band(GO:0036309) regulation of SA node cell action potential(GO:0098907)
0.1 0.9 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.1 0.6 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 0.3 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.7 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.1 0.4 GO:0032484 Ral protein signal transduction(GO:0032484) regulation of Ral protein signal transduction(GO:0032485)
0.1 0.4 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.4 GO:0042631 cellular response to water deprivation(GO:0042631)
0.1 0.9 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.2 GO:0060940 epithelial to mesenchymal transition involved in cardiac fibroblast development(GO:0060940)
0.1 1.0 GO:0007028 cytoplasm organization(GO:0007028)
0.1 0.5 GO:1903923 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.1 0.2 GO:0035790 platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790)
0.1 0.4 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.6 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.1 0.2 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.1 0.5 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 0.1 GO:0042668 auditory receptor cell fate determination(GO:0042668)
0.1 0.6 GO:0015014 protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.2 GO:2000687 negative regulation of rubidium ion transport(GO:2000681) negative regulation of rubidium ion transmembrane transporter activity(GO:2000687)
0.1 0.3 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.2 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.3 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.2 GO:0009443 pyridoxal 5'-phosphate salvage(GO:0009443)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.8 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1 0.5 GO:0044387 negative regulation of protein kinase activity by regulation of protein phosphorylation(GO:0044387)
0.1 0.2 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.3 GO:0060979 vasculogenesis involved in coronary vascular morphogenesis(GO:0060979)
0.0 0.3 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
0.0 0.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.3 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.0 0.1 GO:1900222 regulation of cell growth by extracellular stimulus(GO:0001560) negative regulation of beta-amyloid clearance(GO:1900222)
0.0 0.6 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.6 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.2 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.3 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 1.3 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.1 GO:0046671 negative regulation of cellular pH reduction(GO:0032848) CD8-positive, alpha-beta T cell lineage commitment(GO:0043375) negative regulation of retinal cell programmed cell death(GO:0046671)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.4 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.3 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.0 0.1 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.1 GO:2000297 negative regulation of synapse maturation(GO:2000297)
0.0 0.4 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.3 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.3 GO:0060613 fat pad development(GO:0060613)
0.0 0.3 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.6 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.4 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.1 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.2 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
0.0 0.1 GO:0038098 sequestering of BMP from receptor via BMP binding(GO:0038098)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.0 0.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.6 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.0 0.6 GO:0009642 response to light intensity(GO:0009642) retinal metabolic process(GO:0042574)
0.0 0.3 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.4 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0071321 cellular response to cGMP(GO:0071321)
0.0 0.2 GO:1903593 regulation of histamine secretion by mast cell(GO:1903593)
0.0 0.1 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.0 0.1 GO:0002384 hepatic immune response(GO:0002384)
0.0 0.2 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.2 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.1 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.1 GO:0010216 maintenance of DNA methylation(GO:0010216)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.2 GO:0030050 vesicle transport along actin filament(GO:0030050)
0.0 0.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:0019317 fucose catabolic process(GO:0019317) L-fucose metabolic process(GO:0042354) L-fucose catabolic process(GO:0042355)
0.0 0.4 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.0 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.5 GO:0006907 pinocytosis(GO:0006907)
0.0 0.1 GO:0036289 peptidyl-serine autophosphorylation(GO:0036289)
0.0 0.2 GO:0072718 response to cisplatin(GO:0072718)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0060012 synaptic transmission, glycinergic(GO:0060012)
0.0 0.3 GO:0006089 lactate metabolic process(GO:0006089)
0.0 0.6 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.2 GO:0046325 negative regulation of glucose import(GO:0046325)
0.0 0.0 GO:2000374 regulation of oxygen metabolic process(GO:2000374)
0.0 0.5 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.2 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.1 GO:1904885 beta-catenin destruction complex assembly(GO:1904885)
0.0 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.0 1.2 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.1 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571)
0.0 0.1 GO:0061314 Notch signaling involved in heart development(GO:0061314)
0.0 0.4 GO:0030208 dermatan sulfate biosynthetic process(GO:0030208)
0.0 0.1 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.1 GO:0098917 retrograde trans-synaptic signaling(GO:0098917)
0.0 0.1 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262)
0.0 0.1 GO:0086048 membrane depolarization during bundle of His cell action potential(GO:0086048)
0.0 0.3 GO:0098779 mitophagy in response to mitochondrial depolarization(GO:0098779)
0.0 0.2 GO:0019388 galactose catabolic process(GO:0019388)
0.0 0.6 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.0 0.1 GO:0001554 luteolysis(GO:0001554)
0.0 0.0 GO:0051066 dihydrobiopterin metabolic process(GO:0051066)
0.0 0.1 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.0 0.2 GO:0035058 nonmotile primary cilium assembly(GO:0035058) regulation of nonmotile primary cilium assembly(GO:1902855) positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0097061 dendritic spine morphogenesis(GO:0060997) dendritic spine organization(GO:0097061)
0.0 0.3 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.0 GO:0090425 hepatocyte cell migration(GO:0002194) olfactory placode formation(GO:0030910) otic placode formation(GO:0043049) branching involved in pancreas morphogenesis(GO:0061114) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.0 0.4 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.0 0.1 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1990032 parallel fiber(GO:1990032)
0.2 0.6 GO:0030934 anchoring collagen complex(GO:0030934)
0.1 0.8 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 0.8 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.5 GO:0005826 actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513)
0.1 0.3 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 0.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.5 GO:0070695 FHF complex(GO:0070695)
0.1 0.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 1.2 GO:0033643 host cell part(GO:0033643)
0.1 1.0 GO:0033010 paranodal junction(GO:0033010)
0.1 0.3 GO:0045298 tubulin complex(GO:0045298)
0.1 0.2 GO:0016938 kinesin I complex(GO:0016938)
0.1 0.8 GO:0016600 flotillin complex(GO:0016600)
0.1 0.1 GO:0044308 axonal spine(GO:0044308)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.1 GO:0016935 glycine-gated chloride channel complex(GO:0016935)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.4 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0005901 caveola(GO:0005901)
0.0 0.4 GO:0005638 lamin filament(GO:0005638)
0.0 0.5 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.3 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0071020 post-spliceosomal complex(GO:0071020)
0.0 0.8 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.3 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.1 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.5 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.4 GO:0005883 neurofilament(GO:0005883)
0.0 0.8 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.0 2.9 GO:0031093 platelet alpha granule lumen(GO:0031093)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0043194 axon initial segment(GO:0043194)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.8 GO:0000421 autophagosome membrane(GO:0000421)
0.0 2.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.4 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.4 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 1.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.4 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 0.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.7 GO:0031526 brush border membrane(GO:0031526)
0.0 0.3 GO:1904724 tertiary granule lumen(GO:1904724)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1904288 BAT3 complex binding(GO:1904288)
0.2 0.6 GO:0098770 FBXO family protein binding(GO:0098770)
0.2 0.6 GO:0050119 N-acetylglucosamine deacetylase activity(GO:0050119)
0.1 0.4 GO:0033823 procollagen-lysine 5-dioxygenase activity(GO:0008475) procollagen glucosyltransferase activity(GO:0033823)
0.1 0.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.1 0.3 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.3 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.1 0.3 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 0.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 1.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.4 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.6 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.1 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.2 GO:0019107 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.1 0.4 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.3 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.7 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.2 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.1 0.7 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 0.2 GO:0004119 cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119)
0.1 0.2 GO:0008478 pyridoxal kinase activity(GO:0008478) lithium ion binding(GO:0031403)
0.1 0.6 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.2 GO:0052810 1-phosphatidylinositol-5-kinase activity(GO:0052810)
0.0 0.1 GO:0000384 first spliceosomal transesterification activity(GO:0000384)
0.0 0.7 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.3 GO:0044736 acid-sensing ion channel activity(GO:0044736)
0.0 0.8 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.2 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.2 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.8 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.5 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.2 GO:0004340 glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) intronic transcription regulatory region DNA binding(GO:0044213)
0.0 0.7 GO:0005248 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.2 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.2 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.4 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 3.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.1 GO:0038049 transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049)
0.0 0.7 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.6 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.8 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.0 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.3 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.2 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.1 GO:0000990 transcription factor activity, core RNA polymerase binding(GO:0000990)
0.0 0.4 GO:0044325 ion channel binding(GO:0044325)
0.0 0.1 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.2 GO:0017049 GTP-Rho binding(GO:0017049)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.9 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.7 PID_HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID_TCR_RAS_PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 2.0 PID_RAS_PATHWAY Regulation of Ras family activation
0.0 0.4 SA_G2_AND_M_PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.6 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.7 PID_NECTIN_PATHWAY Nectin adhesion pathway
0.0 0.7 PID_IL2_STAT5_PATHWAY IL2 signaling events mediated by STAT5
0.0 0.4 PID_S1P_S1P4_PATHWAY S1P4 pathway
0.0 1.1 PID_RET_PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.9 PID_IL3_PATHWAY IL3-mediated signaling events
0.0 1.5 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.9 PID_TAP63_PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.2 PID_PDGFRA_PATHWAY PDGFR-alpha signaling pathway
0.0 0.5 PID_MAPK_TRK_PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 1.1 PID_RAC1_REG_PATHWAY Regulation of RAC1 activity
0.0 0.1 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.6 NABA_COLLAGENS Genes encoding collagen proteins
0.0 0.7 PID_RAC1_PATHWAY RAC1 signaling pathway

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 2.8 REACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.6 REACTOME_RAF_MAP_KINASE_CASCADE Genes involved in RAF/MAP kinase cascade
0.0 1.5 REACTOME_RAP1_SIGNALLING Genes involved in Rap1 signalling
0.0 0.4 REACTOME_E2F_ENABLED_INHIBITION_OF_PRE_REPLICATION_COMPLEX_FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.2 REACTOME_RECEPTOR_LIGAND_BINDING_INITIATES_THE_SECOND_PROTEOLYTIC_CLEAVAGE_OF_NOTCH_RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.2 REACTOME_MEMBRANE_BINDING_AND_TARGETTING_OF_GAG_PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.4 REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME_ADHERENS_JUNCTIONS_INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME_SIGNALING_BY_CONSTITUTIVELY_ACTIVE_EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.5 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.0 0.9 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.7 REACTOME_PYRIMIDINE_METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.7 REACTOME_HS_GAG_BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME_THE_ACTIVATION_OF_ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME_CLASS_C_3_METABOTROPIC_GLUTAMATE_PHEROMONE_RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 1.0 REACTOME_COLLAGEN_FORMATION Genes involved in Collagen formation
0.0 0.6 REACTOME_SEMA4D_INDUCED_CELL_MIGRATION_AND_GROWTH_CONE_COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.4 REACTOME_PYRUVATE_METABOLISM Genes involved in Pyruvate metabolism
0.0 0.6 REACTOME_METABOLISM_OF_STEROID_HORMONES_AND_VITAMINS_A_AND_D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.5 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME_TRANSPORT_OF_VITAMINS_NUCLEOSIDES_AND_RELATED_MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME_CASPASE_MEDIATED_CLEAVAGE_OF_CYTOSKELETAL_PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1