Motif ID: HDX

Z-value: 0.231


Transcription factors associated with HDX:

Gene SymbolEntrez IDGene Name
HDX ENSG00000165259.9 HDX

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HDXhg19_v2_chrX_-_83757399_837574870.331.1e-01Click!


Activity profile for motif HDX.

activity profile for motif HDX


Sorted Z-values histogram for motif HDX

Sorted Z-values for motif HDX



Network of associatons between targets according to the STRING database.



First level regulatory network of HDX

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_113594279 0.255 ENST00000416750.1
ENST00000418817.1
ENST00000263341.2
 IL1B


interleukin 1, beta


chr5_-_35230434 0.217 ENST00000504500.1
 PRLR
prolactin receptor
chr7_-_69062391 0.206 ENST00000436600.2
 RP5-942I16.1
RP5-942I16.1
chr2_+_128403720 0.190 ENST00000272644.3
 GPR17
G protein-coupled receptor 17
chr12_+_101869096 0.181 ENST00000551346.1
 SPIC
Spi-C transcription factor (Spi-1/PU.1 related)
chr2_+_128403439 0.179 ENST00000544369.1
 GPR17
G protein-coupled receptor 17
chr1_+_84630053 0.142 ENST00000394838.2
ENST00000370682.3
ENST00000432111.1
 PRKACB


protein kinase, cAMP-dependent, catalytic, beta


chr18_+_29027696 0.140 ENST00000257189.4
 DSG3
desmoglein 3
chr7_-_121944491 0.123 ENST00000331178.4
ENST00000427185.2
ENST00000442488.2
 FEZF1


FEZ family zinc finger 1


chr12_+_10460549 0.118 ENST00000543420.1
ENST00000543777.1
 KLRD1

killer cell lectin-like receptor subfamily D, member 1

chr2_+_113735575 0.113 ENST00000376489.2
ENST00000259205.4
 IL36G

interleukin 36, gamma

chr5_+_60933634 0.094 ENST00000505642.1
 C5orf64
chromosome 5 open reading frame 64
chr5_-_41213607 0.094 ENST00000337836.5
ENST00000433294.1
 C6

complement component 6

chr1_+_117602925 0.087 ENST00000369466.4
 TTF2
transcription termination factor, RNA polymerase II
chr10_-_14372870 0.085 ENST00000357447.2
 FRMD4A
FERM domain containing 4A
chr3_-_165555200 0.085 ENST00000479451.1
ENST00000540653.1
ENST00000488954.1
ENST00000264381.3
 BCHE



butyrylcholinesterase



chr12_+_10460417 0.074 ENST00000381908.3
ENST00000336164.4
ENST00000350274.5
 KLRD1


killer cell lectin-like receptor subfamily D, member 1


chr7_+_99954224 0.073 ENST00000608825.1
 PILRB
paired immunoglobin-like type 2 receptor beta
chr9_+_35538616 0.064 ENST00000455600.1
 RUSC2
RUN and SH3 domain containing 2
chr12_+_54422142 0.058 ENST00000243108.4
 HOXC6
homeobox C6
chr22_+_40440804 0.052 ENST00000441751.1
ENST00000301923.9
 TNRC6B

trinucleotide repeat containing 6B

chr1_-_169680745 0.043 ENST00000236147.4
 SELL
selectin L
chr5_-_35230649 0.040 ENST00000382002.5
 PRLR
prolactin receptor
chr14_+_79745682 0.040 ENST00000557594.1
 NRXN3
neurexin 3
chr15_-_54025300 0.037 ENST00000559418.1
 WDR72
WD repeat domain 72
chr5_-_35230771 0.035 ENST00000342362.5
 PRLR
prolactin receptor
chr1_-_11024258 0.034 ENST00000418570.2
 C1orf127
chromosome 1 open reading frame 127
chr6_+_144471643 0.031 ENST00000367568.4
 STX11
syntaxin 11
chr11_-_66675371 0.030 ENST00000393955.2
 PC
pyruvate carboxylase
chr12_-_31743901 0.027 ENST00000354285.4
 DENND5B
DENN/MADD domain containing 5B
chr2_-_40657397 0.026 ENST00000408028.2
ENST00000332839.4
ENST00000406391.2
ENST00000542024.1
ENST00000542756.1
ENST00000405901.3
 SLC8A1





solute carrier family 8 (sodium/calcium exchanger), member 1





chr2_+_169926047 0.021 ENST00000428522.1
ENST00000450153.1
ENST00000421653.1
 DHRS9


dehydrogenase/reductase (SDR family) member 9


chr19_-_41934635 0.020 ENST00000321702.2
 B3GNT8
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 8
chr8_+_24151620 0.016 ENST00000437154.2
 ADAM28
ADAM metallopeptidase domain 28
chr18_-_53804580 0.015 ENST00000590484.1
ENST00000589293.1
ENST00000587904.1
ENST00000591974.1
 RP11-456O19.4



RP11-456O19.4



chr2_+_87754887 0.012 ENST00000409054.1
ENST00000331944.6
ENST00000409139.1
 LINC00152


long intergenic non-protein coding RNA 152


chr11_+_9685604 0.012 ENST00000447399.2
ENST00000318950.6
 SWAP70

SWAP switching B-cell complex 70kDa subunit

chr6_+_42584847 0.011 ENST00000372883.3
 UBR2
ubiquitin protein ligase E3 component n-recognin 2
chr1_+_197237352 0.009 ENST00000538660.1
ENST00000367400.3
ENST00000367399.2
 CRB1


crumbs homolog 1 (Drosophila)


chrX_+_55649833 0.005 ENST00000339140.3
 FOXR2
forkhead box R2
chr13_+_24144509 0.004 ENST00000248484.4
 TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr3_+_54157480 0.002 ENST00000490478.1
 CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr16_+_1877204 0.001 ENST00000427358.2
 FAHD1
fumarylacetoacetate hydrolase domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0060557 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.3 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.1 GO:0014016 neuroblast differentiation(GO:0014016)
0.0 0.1 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.1 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.0 0.4 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005579 membrane attack complex(GO:0005579)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0004925 prolactin receptor activity(GO:0004925)
0.0 0.2 GO:0023024 MHC class I protein complex binding(GO:0023024)
0.0 0.1 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.0 0.4 GO:0005149 interleukin-1 receptor binding(GO:0005149)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME_P2Y_RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME_PROLACTIN_RECEPTOR_SIGNALING Genes involved in Prolactin receptor signaling