Motif ID: HES1

Z-value: 0.654


Transcription factors associated with HES1:

Gene SymbolEntrez IDGene Name
HES1 ENSG00000114315.3 HES1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HES1hg19_v2_chr3_+_193853927_1938539440.116.2e-01Click!


Activity profile for motif HES1.

activity profile for motif HES1


Sorted Z-values histogram for motif HES1

Sorted Z-values for motif HES1



Network of associatons between targets according to the STRING database.



First level regulatory network of HES1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_+_86159821 2.102 ENST00000369651.3
NT5E
5'-nucleotidase, ecto (CD73)
chr1_-_9189229 1.841 ENST00000377411.4
GPR157
G protein-coupled receptor 157
chr18_+_33877654 1.738 ENST00000257209.4
ENST00000445677.1
ENST00000590592.1
ENST00000359247.4
FHOD3



formin homology 2 domain containing 3



chr20_-_43280325 1.277 ENST00000537820.1
ADA
adenosine deaminase
chr6_+_151646800 1.193 ENST00000354675.6
AKAP12
A kinase (PRKA) anchor protein 12
chr21_-_44495919 1.130 ENST00000398158.1
CBS
cystathionine-beta-synthase
chr4_+_17812525 1.071 ENST00000251496.2
NCAPG
non-SMC condensin I complex, subunit G
chr7_+_130131907 1.003 ENST00000223215.4
ENST00000437945.1
MEST

mesoderm specific transcript

chr9_+_91926103 0.982 ENST00000314355.6
CKS2
CDC28 protein kinase regulatory subunit 2
chr20_+_37554955 0.970 ENST00000217429.4
FAM83D
family with sequence similarity 83, member D
chr18_-_33077556 0.966 ENST00000589273.1
ENST00000586489.1
INO80C

INO80 complex subunit C

chr6_+_86159765 0.943 ENST00000369646.3
ENST00000257770.3
NT5E

5'-nucleotidase, ecto (CD73)

chr4_-_185655278 0.935 ENST00000281453.5
MLF1IP
centromere protein U
chr2_+_201390843 0.907 ENST00000357799.4
ENST00000409203.3
SGOL2

shugoshin-like 2 (S. pombe)

chr7_-_148581251 0.896 ENST00000478654.1
ENST00000460911.1
ENST00000350995.2
EZH2


enhancer of zeste homolog 2 (Drosophila)


chr11_+_43964055 0.847 ENST00000528572.1
C11orf96
chromosome 11 open reading frame 96
chr11_-_71318487 0.815 ENST00000343767.3
AP000867.1
AP000867.1
chr7_-_148581360 0.812 ENST00000320356.2
ENST00000541220.1
ENST00000483967.1
ENST00000536783.1
EZH2



enhancer of zeste homolog 2 (Drosophila)



chr8_-_95908902 0.808 ENST00000520509.1
CCNE2
cyclin E2
chr1_-_53793725 0.806 ENST00000371454.2
LRP8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr19_-_19051927 0.796 ENST00000600077.1
HOMER3
homer homolog 3 (Drosophila)
chr12_-_125348448 0.776 ENST00000339570.5
SCARB1
scavenger receptor class B, member 1
chr12_-_125348329 0.769 ENST00000546215.1
ENST00000415380.2
ENST00000261693.6
ENST00000376788.1
ENST00000545493.1
SCARB1




scavenger receptor class B, member 1




chr19_-_19051993 0.766 ENST00000594794.1
ENST00000355887.6
ENST00000392351.3
ENST00000596482.1
HOMER3



homer homolog 3 (Drosophila)



chr6_+_31126291 0.752 ENST00000376257.3
ENST00000376255.4
TCF19

transcription factor 19

chr7_+_24613034 0.722 ENST00000409761.1
ENST00000396475.2
MPP6

membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)

chr5_-_159797627 0.716 ENST00000393975.3
C1QTNF2
C1q and tumor necrosis factor related protein 2
chr11_+_65029421 0.716 ENST00000541089.1
POLA2
polymerase (DNA directed), alpha 2, accessory subunit
chr6_-_31869769 0.655 ENST00000375527.2
ZBTB12
zinc finger and BTB domain containing 12
chr1_-_54303949 0.654 ENST00000234725.8
NDC1
NDC1 transmembrane nucleoporin
chrX_-_106960285 0.644 ENST00000503515.1
ENST00000372397.2
TSC22D3

TSC22 domain family, member 3

chr21_-_40685536 0.642 ENST00000341322.4
BRWD1
bromodomain and WD repeat domain containing 1
chr7_-_99698338 0.635 ENST00000354230.3
ENST00000425308.1
MCM7

minichromosome maintenance complex component 7

chr1_+_41445413 0.613 ENST00000541520.1
CTPS1
CTP synthase 1
chr1_+_91966656 0.608 ENST00000428239.1
ENST00000426137.1
CDC7

cell division cycle 7

chr16_-_72127456 0.604 ENST00000562153.1
TXNL4B
thioredoxin-like 4B
chr7_+_130126165 0.590 ENST00000427521.1
ENST00000416162.2
ENST00000378576.4
MEST


mesoderm specific transcript


chr17_+_74381343 0.588 ENST00000392496.3
SPHK1
sphingosine kinase 1
chrX_-_109561294 0.588 ENST00000372059.2
ENST00000262844.5
AMMECR1

Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1

chr2_-_25142708 0.586 ENST00000260600.5
ENST00000435135.1
ADCY3

adenylate cyclase 3

chr2_-_136633940 0.583 ENST00000264156.2
MCM6
minichromosome maintenance complex component 6
chr1_-_113498943 0.583 ENST00000369626.3
SLC16A1
solute carrier family 16 (monocarboxylate transporter), member 1
chr1_-_54303934 0.578 ENST00000537333.1
NDC1
NDC1 transmembrane nucleoporin
chr12_+_1099675 0.574 ENST00000545318.2
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr14_+_20937538 0.559 ENST00000361505.5
ENST00000553591.1
PNP

purine nucleoside phosphorylase

chr1_-_113498616 0.546 ENST00000433570.4
ENST00000538576.1
ENST00000458229.1
SLC16A1


solute carrier family 16 (monocarboxylate transporter), member 1


chr1_-_118472171 0.543 ENST00000369442.3
GDAP2
ganglioside induced differentiation associated protein 2
chr9_-_136242909 0.541 ENST00000371991.3
ENST00000545297.1
SURF4

surfeit 4

chr1_+_28844778 0.529 ENST00000411533.1
RCC1
regulator of chromosome condensation 1
chr2_-_224702740 0.527 ENST00000444408.1
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr19_-_1652575 0.526 ENST00000587235.1
ENST00000262965.5
TCF3

transcription factor 3

chrX_-_131623874 0.524 ENST00000436215.1
MBNL3
muscleblind-like splicing regulator 3
chr19_-_55919087 0.518 ENST00000587845.1
ENST00000589978.1
ENST00000264552.9
UBE2S


ubiquitin-conjugating enzyme E2S


chr6_-_150346607 0.504 ENST00000367341.1
ENST00000286380.2
RAET1L

retinoic acid early transcript 1L

chr2_+_192543153 0.500 ENST00000425611.2
NABP1
nucleic acid binding protein 1
chr7_-_558876 0.499 ENST00000354513.5
ENST00000402802.3
PDGFA

platelet-derived growth factor alpha polypeptide

chr9_+_116037922 0.499 ENST00000374198.4
PRPF4
pre-mRNA processing factor 4
chr1_+_165797024 0.496 ENST00000372212.4
UCK2
uridine-cytidine kinase 2
chr2_-_224702201 0.494 ENST00000446015.2
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr8_+_124194752 0.493 ENST00000318462.6
FAM83A
family with sequence similarity 83, member A
chr12_-_124018252 0.492 ENST00000376874.4
RILPL1
Rab interacting lysosomal protein-like 1
chr1_+_23037323 0.492 ENST00000544305.1
ENST00000374630.3
ENST00000400191.3
ENST00000374632.3
EPHB2



EPH receptor B2



chr1_-_231175964 0.490 ENST00000366654.4
FAM89A
family with sequence similarity 89, member A
chr8_+_92082424 0.489 ENST00000285420.4
ENST00000404789.3
OTUD6B

OTU domain containing 6B

chr1_+_152881014 0.482 ENST00000368764.3
ENST00000392667.2
IVL

involucrin

chr10_-_90751038 0.480 ENST00000458159.1
ENST00000415557.1
ENST00000458208.1
ACTA2


actin, alpha 2, smooth muscle, aorta


chr18_-_33077942 0.473 ENST00000334598.7
INO80C
INO80 complex subunit C
chr19_+_30302805 0.469 ENST00000262643.3
ENST00000575243.1
ENST00000357943.5
CCNE1


cyclin E1


chr21_-_44495964 0.465 ENST00000398168.1
ENST00000398165.3
CBS

cystathionine-beta-synthase

chr2_+_208576259 0.459 ENST00000392209.3
CCNYL1
cyclin Y-like 1
chrX_-_51239425 0.459 ENST00000375992.3
NUDT11
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr2_-_224702257 0.458 ENST00000409375.1
AP1S3
adaptor-related protein complex 1, sigma 3 subunit
chr16_-_46865286 0.449 ENST00000285697.4
C16orf87
chromosome 16 open reading frame 87
chr19_+_34287174 0.441 ENST00000587559.1
ENST00000588637.1
KCTD15

potassium channel tetramerization domain containing 15

chr12_+_122064673 0.440 ENST00000537188.1
ORAI1
ORAI calcium release-activated calcium modulator 1
chr2_-_224702270 0.440 ENST00000396654.2
ENST00000396653.2
ENST00000423110.1
ENST00000443700.1
AP1S3



adaptor-related protein complex 1, sigma 3 subunit



chr2_+_192542850 0.422 ENST00000410026.2
NABP1
nucleic acid binding protein 1
chr1_-_53793584 0.417 ENST00000354412.3
ENST00000347547.2
ENST00000306052.6
LRP8


low density lipoprotein receptor-related protein 8, apolipoprotein e receptor


chr6_+_43543864 0.416 ENST00000372236.4
ENST00000535400.1
POLH

polymerase (DNA directed), eta

chr12_-_122238464 0.411 ENST00000546227.1
RHOF
ras homolog family member F (in filopodia)
chr15_-_63674034 0.411 ENST00000344366.3
ENST00000422263.2
CA12

carbonic anhydrase XII

chr9_-_94186131 0.401 ENST00000297689.3
NFIL3
nuclear factor, interleukin 3 regulated
chr1_+_153950202 0.400 ENST00000608236.1
RP11-422P24.11
RP11-422P24.11
chr7_+_155089486 0.397 ENST00000340368.4
ENST00000344756.4
ENST00000425172.1
ENST00000342407.5
INSIG1



insulin induced gene 1



chr8_+_66556936 0.396 ENST00000262146.4
MTFR1
mitochondrial fission regulator 1
chr5_+_149737202 0.394 ENST00000451292.1
ENST00000377797.3
ENST00000445265.2
ENST00000323668.7
ENST00000439160.2
ENST00000394269.3
ENST00000427724.2
ENST00000504761.2
ENST00000513346.1
ENST00000515516.1
TCOF1









Treacher Collins-Franceschetti syndrome 1









chr8_-_145515055 0.391 ENST00000526552.1
ENST00000529231.1
ENST00000307404.5
BOP1


block of proliferation 1


chr2_+_64681641 0.388 ENST00000409537.2
LGALSL
lectin, galactoside-binding-like
chr21_-_44846999 0.388 ENST00000270162.6
SIK1
salt-inducible kinase 1
chrX_+_21958814 0.387 ENST00000379404.1
ENST00000415881.2
SMS

spermine synthase

chr1_-_54304212 0.377 ENST00000540001.1
NDC1
NDC1 transmembrane nucleoporin
chr1_-_43424500 0.373 ENST00000415851.2
ENST00000426263.3
ENST00000372500.3
SLC2A1


solute carrier family 2 (facilitated glucose transporter), member 1


chr2_-_47143160 0.373 ENST00000409800.1
ENST00000409218.1
MCFD2

multiple coagulation factor deficiency 2

chrX_+_152907913 0.372 ENST00000370167.4
DUSP9
dual specificity phosphatase 9
chr1_+_44445549 0.371 ENST00000356836.6
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr14_-_100070363 0.370 ENST00000380243.4
CCDC85C
coiled-coil domain containing 85C
chr13_+_21277482 0.365 ENST00000304920.3
IL17D
interleukin 17D
chr2_+_204193129 0.364 ENST00000417864.1
ABI2
abl-interactor 2
chr5_-_172662303 0.362 ENST00000517440.1
ENST00000329198.4
NKX2-5

NK2 homeobox 5

chr19_+_4402659 0.359 ENST00000301280.5
ENST00000585854.1
CHAF1A

chromatin assembly factor 1, subunit A (p150)

chr17_-_1394940 0.357 ENST00000570984.2
ENST00000361007.2
MYO1C

myosin IC

chr2_-_47142884 0.354 ENST00000409105.1
ENST00000409973.1
ENST00000409913.1
ENST00000319466.4
MCFD2



multiple coagulation factor deficiency 2



chr2_+_208576355 0.347 ENST00000420822.1
ENST00000295414.3
ENST00000339882.5
CCNYL1


cyclin Y-like 1


chr18_+_48086440 0.346 ENST00000400384.2
ENST00000540640.1
ENST00000592595.1
MAPK4


mitogen-activated protein kinase 4


chr14_-_91282726 0.346 ENST00000328459.6
ENST00000357056.2
TTC7B

tetratricopeptide repeat domain 7B

chr5_+_612387 0.343 ENST00000264935.5
ENST00000444221.1
CEP72

centrosomal protein 72kDa

chr3_-_179169330 0.341 ENST00000232564.3
GNB4
guanine nucleotide binding protein (G protein), beta polypeptide 4
chr10_-_99447024 0.332 ENST00000370626.3
AVPI1
arginine vasopressin-induced 1
chr8_+_41386761 0.332 ENST00000523277.2
GINS4
GINS complex subunit 4 (Sld5 homolog)
chr2_-_101925055 0.329 ENST00000295317.3
RNF149
ring finger protein 149
chr12_+_96588279 0.329 ENST00000552142.1
ELK3
ELK3, ETS-domain protein (SRF accessory protein 2)
chr13_+_52158610 0.329 ENST00000298125.5
WDFY2
WD repeat and FYVE domain containing 2
chr11_+_65029233 0.326 ENST00000265465.3
POLA2
polymerase (DNA directed), alpha 2, accessory subunit
chr3_-_179754806 0.326 ENST00000485199.1
PEX5L
peroxisomal biogenesis factor 5-like
chr10_+_75936444 0.326 ENST00000372734.3
ENST00000541550.1
ADK

adenosine kinase

chr12_-_113909877 0.322 ENST00000261731.3
LHX5
LIM homeobox 5
chr22_+_38302285 0.322 ENST00000215957.6
MICALL1
MICAL-like 1
chr17_-_56565736 0.320 ENST00000323777.3
HSF5
heat shock transcription factor family member 5
chr11_+_124932955 0.319 ENST00000403796.2
SLC37A2
solute carrier family 37 (glucose-6-phosphate transporter), member 2
chr14_-_53162361 0.319 ENST00000395686.3
ERO1L
ERO1-like (S. cerevisiae)
chr6_+_20403997 0.317 ENST00000535432.1
E2F3
E2F transcription factor 3
chr21_-_47648665 0.316 ENST00000450351.1
ENST00000522411.1
ENST00000356396.4
ENST00000397728.3
ENST00000457828.2
LSS




lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)




chr17_-_7297519 0.315 ENST00000576362.1
ENST00000571078.1
TMEM256-PLSCR3

TMEM256-PLSCR3 readthrough (NMD candidate)

chr14_+_100070869 0.314 ENST00000502101.2
RP11-543C4.1
RP11-543C4.1
chr8_+_32406179 0.310 ENST00000405005.3
NRG1
neuregulin 1
chr8_+_31496809 0.307 ENST00000518104.1
ENST00000519301.1
NRG1

neuregulin 1

chr6_+_43738444 0.307 ENST00000324450.6
ENST00000417285.2
ENST00000413642.3
ENST00000372055.4
ENST00000482630.2
ENST00000425836.2
ENST00000372064.4
ENST00000372077.4
ENST00000519767.1
VEGFA








vascular endothelial growth factor A








chr20_+_6748311 0.307 ENST00000378827.4
BMP2
bone morphogenetic protein 2
chr19_-_8373173 0.307 ENST00000537716.2
ENST00000301458.5
CD320

CD320 molecule

chr8_+_145515263 0.305 ENST00000528838.1
HSF1
heat shock transcription factor 1
chr10_-_75634219 0.304 ENST00000305762.7
CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr1_+_44444865 0.303 ENST00000372324.1
B4GALT2
UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 2
chr11_+_124932986 0.303 ENST00000407458.1
ENST00000298280.5
SLC37A2

solute carrier family 37 (glucose-6-phosphate transporter), member 2

chr2_+_204193149 0.303 ENST00000422511.2
ABI2
abl-interactor 2
chr2_+_113239710 0.302 ENST00000233336.6
TTL
tubulin tyrosine ligase
chr6_-_105850937 0.300 ENST00000369110.3
PREP
prolyl endopeptidase
chr9_-_126692386 0.298 ENST00000373624.2
ENST00000394219.3
ENST00000373620.3
ENST00000394215.2
ENST00000373618.1
DENND1A




DENN/MADD domain containing 1A




chr10_+_74033672 0.298 ENST00000307365.3
DDIT4
DNA-damage-inducible transcript 4
chr5_-_132112907 0.295 ENST00000458488.2
SEPT8
septin 8
chr11_+_63580855 0.293 ENST00000294244.4
C11orf84
chromosome 11 open reading frame 84
chr15_+_89182178 0.292 ENST00000559876.1
ISG20
interferon stimulated exonuclease gene 20kDa
chr12_-_53614155 0.292 ENST00000543726.1
RARG
retinoic acid receptor, gamma
chr18_+_12308231 0.291 ENST00000590103.1
ENST00000591909.1
ENST00000586653.1
ENST00000592683.1
ENST00000590967.1
ENST00000591208.1
ENST00000591463.1
TUBB6






tubulin, beta 6 class V






chr17_-_79849438 0.289 ENST00000331204.4
ENST00000505490.2
ALYREF

Aly/REF export factor

chr11_+_124933191 0.288 ENST00000532000.1
ENST00000308074.4
SLC37A2

solute carrier family 37 (glucose-6-phosphate transporter), member 2

chr5_-_132112921 0.285 ENST00000378721.4
ENST00000378701.1
SEPT8

septin 8

chr11_-_134093827 0.284 ENST00000534548.2
NCAPD3
non-SMC condensin II complex, subunit D3
chr15_-_63674218 0.282 ENST00000178638.3
CA12
carbonic anhydrase XII
chr8_+_22298578 0.281 ENST00000240139.5
ENST00000289963.8
ENST00000397775.3
PPP3CC


protein phosphatase 3, catalytic subunit, gamma isozyme


chr12_+_121416437 0.281 ENST00000402929.1
ENST00000535955.1
ENST00000538626.1
ENST00000543427.1
HNF1A



HNF1 homeobox A



chr6_+_43739697 0.280 ENST00000230480.6
VEGFA
vascular endothelial growth factor A
chr3_+_51422478 0.280 ENST00000528157.1
MANF
mesencephalic astrocyte-derived neurotrophic factor
chr12_-_53614043 0.276 ENST00000338561.5
RARG
retinoic acid receptor, gamma
chr12_+_49761147 0.275 ENST00000549298.1
SPATS2
spermatogenesis associated, serine-rich 2
chr12_-_106641728 0.275 ENST00000378026.4
CKAP4
cytoskeleton-associated protein 4
chr19_+_10982336 0.272 ENST00000344150.4
CARM1
coactivator-associated arginine methyltransferase 1
chr10_-_105110831 0.272 ENST00000337211.4
PCGF6
polycomb group ring finger 6
chr16_+_72127461 0.271 ENST00000268482.3
ENST00000566794.1
DHX38

DEAH (Asp-Glu-Ala-His) box polypeptide 38

chr18_-_33077868 0.271 ENST00000590757.1
ENST00000592173.1
ENST00000441607.2
ENST00000587450.1
ENST00000589258.1
INO80C



RP11-322E11.6
INO80 complex subunit C



Uncharacterized protein
chr16_+_72127670 0.270 ENST00000536867.1
DHX38
DEAH (Asp-Glu-Ala-His) box polypeptide 38
chr19_+_33071974 0.270 ENST00000590247.2
ENST00000419343.3
ENST00000592786.1
ENST00000379316.3
PDCD5



programmed cell death 5



chr16_+_16043406 0.269 ENST00000399410.3
ENST00000399408.2
ENST00000346370.5
ENST00000351154.5
ENST00000345148.5
ENST00000349029.5
ABCC1





ATP-binding cassette, sub-family C (CFTR/MRP), member 1





chr19_+_50887585 0.269 ENST00000440232.2
ENST00000601098.1
ENST00000599857.1
ENST00000593887.1
POLD1



polymerase (DNA directed), delta 1, catalytic subunit



chr9_+_101867387 0.269 ENST00000374990.2
ENST00000552516.1
TGFBR1

transforming growth factor, beta receptor 1

chr1_+_44401479 0.269 ENST00000438616.3
ARTN
artemin
chr19_+_11670245 0.269 ENST00000585493.1
ZNF627
zinc finger protein 627
chr10_-_105110890 0.268 ENST00000369847.3
PCGF6
polycomb group ring finger 6
chr8_+_124428959 0.267 ENST00000287387.2
ENST00000523984.1
WDYHV1

WDYHV motif containing 1

chr19_-_14201776 0.264 ENST00000269724.5
SAMD1
sterile alpha motif domain containing 1
chr1_-_8086343 0.262 ENST00000474874.1
ENST00000469499.1
ENST00000377482.5
ERRFI1


ERBB receptor feedback inhibitor 1


chr19_-_48673552 0.262 ENST00000536218.1
ENST00000596549.1
LIG1

ligase I, DNA, ATP-dependent

chr4_+_57302297 0.260 ENST00000399688.3
ENST00000512576.1
PAICS

phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoimidazole succinocarboxamide synthetase

chr20_+_23471727 0.259 ENST00000449810.1
ENST00000246012.1
CST8

cystatin 8 (cystatin-related epididymal specific)

chr18_+_12947981 0.258 ENST00000262124.11
SEH1L
SEH1-like (S. cerevisiae)
chr3_+_183415558 0.258 ENST00000305135.5
YEATS2
YEATS domain containing 2
chr6_-_10419871 0.257 ENST00000319516.4
TFAP2A
transcription factor AP-2 alpha (activating enhancer binding protein 2 alpha)
chr3_+_182971583 0.257 ENST00000460419.1
B3GNT5
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5
chr5_-_180632147 0.256 ENST00000274773.7
TRIM7
tripartite motif containing 7
chr17_-_79828850 0.254 ENST00000541078.2
ARHGDIA
Rho GDP dissociation inhibitor (GDI) alpha
chr1_-_154946825 0.253 ENST00000368453.4
ENST00000368450.1
ENST00000366442.2
SHC1


SHC (Src homology 2 domain containing) transforming protein 1


chrX_-_153285395 0.253 ENST00000369980.3
IRAK1
interleukin-1 receptor-associated kinase 1
chr19_-_40896081 0.253 ENST00000291823.2
HIPK4
homeodomain interacting protein kinase 4
chr18_+_77794358 0.252 ENST00000306735.5
RBFA
ribosome binding factor A (putative)
chr12_+_121416340 0.252 ENST00000257555.6
ENST00000400024.2
HNF1A

HNF1 homeobox A

chr9_-_130331297 0.251 ENST00000373312.3
FAM129B
family with sequence similarity 129, member B
chr3_-_179754556 0.250 ENST00000263962.8
PEX5L
peroxisomal biogenesis factor 5-like
chr10_+_3109695 0.249 ENST00000381125.4
PFKP
phosphofructokinase, platelet
chr18_+_77794446 0.247 ENST00000262197.7
RBFA
ribosome binding factor A (putative)
chrX_+_101380642 0.245 ENST00000372780.1
ENST00000329035.2
TCEAL2

transcription elongation factor A (SII)-like 2

chr8_+_95653427 0.241 ENST00000454170.2
ESRP1
epithelial splicing regulatory protein 1
chrX_-_153285251 0.241 ENST00000444230.1
ENST00000393682.1
ENST00000393687.2
ENST00000429936.2
ENST00000369974.2
IRAK1




interleukin-1 receptor-associated kinase 1




chr18_+_77623668 0.241 ENST00000316249.3
KCNG2
potassium voltage-gated channel, subfamily G, member 2
chr17_-_74722536 0.241 ENST00000585429.1
JMJD6
jumonji domain containing 6
chr7_-_27239703 0.240 ENST00000222753.4
HOXA13
homeobox A13
chr19_+_39616410 0.240 ENST00000602004.1
ENST00000599470.1
ENST00000321944.4
ENST00000593480.1
ENST00000358301.3
ENST00000593690.1
ENST00000599386.1
PAK4






p21 protein (Cdc42/Rac)-activated kinase 4






chr19_+_34855874 0.240 ENST00000588991.2
GPI
glucose-6-phosphate isomerase
chr8_+_38614807 0.239 ENST00000330691.6
ENST00000348567.4
TACC1

transforming, acidic coiled-coil containing protein 1

chr6_-_45345597 0.238 ENST00000371460.1
ENST00000371459.1
SUPT3H

suppressor of Ty 3 homolog (S. cerevisiae)

chr16_+_66638003 0.238 ENST00000562357.1
ENST00000360086.4
ENST00000562707.1
ENST00000361909.4
ENST00000460097.1
ENST00000565666.1
CMTM3





CKLF-like MARVEL transmembrane domain containing 3





chr15_-_56285742 0.237 ENST00000435532.3
NEDD4
neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.4 GO:0046086 adenosine biosynthetic process(GO:0046086)
0.6 1.7 GO:0036333 hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772)
0.5 1.6 GO:0071790 spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790)
0.5 1.6 GO:0006535 cysteine biosynthetic process from serine(GO:0006535)
0.5 1.5 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.5 1.8 GO:0046102 inosine metabolic process(GO:0046102)
0.4 1.1 GO:0051780 mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780)
0.3 0.8 GO:0035623 regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623)
0.2 1.6 GO:0007498 mesoderm development(GO:0007498)
0.2 0.7 GO:0019242 methylglyoxal biosynthetic process(GO:0019242)
0.2 0.6 GO:0044210 'de novo' CTP biosynthetic process(GO:0044210)
0.2 0.6 GO:0046521 sphingoid catabolic process(GO:0046521)
0.2 0.6 GO:1903570 regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572)
0.2 0.6 GO:0008355 olfactory learning(GO:0008355)
0.2 0.6 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 0.8 GO:0003342 proepicardium development(GO:0003342) septum transversum development(GO:0003343)
0.2 0.5 GO:0018153 isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262)
0.2 0.2 GO:0032808 lacrimal gland development(GO:0032808)
0.2 1.2 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 0.4 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.1 1.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.4 GO:0035281 pre-miRNA export from nucleus(GO:0035281)
0.1 0.7 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.1 GO:0043987 regulation of histone phosphorylation(GO:0033127) positive regulation of histone phosphorylation(GO:0033129) histone-serine phosphorylation(GO:0035404) histone H3-S10 phosphorylation(GO:0043987) histone H3-S28 phosphorylation(GO:0043988)
0.1 0.4 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.5 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.4 GO:0005988 lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989)
0.1 0.5 GO:0046035 CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035)
0.1 0.5 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.1 1.2 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.7 GO:0055064 chloride ion homeostasis(GO:0055064)
0.1 1.8 GO:0060019 radial glial cell differentiation(GO:0060019)
0.1 0.6 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430) Harderian gland development(GO:0070384)
0.1 0.4 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
0.1 0.1 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 1.7 GO:0051639 actin filament network formation(GO:0051639)
0.1 0.4 GO:0003308 negative regulation of Wnt signaling pathway involved in heart development(GO:0003308)
0.1 0.3 GO:1900365 positive regulation of mRNA polyadenylation(GO:1900365) positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 0.5 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.1 0.4 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.1 0.5 GO:0072144 glomerular mesangial cell development(GO:0072144)
0.1 0.8 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.1 0.4 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.1 0.6 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.1 0.3 GO:0016572 histone phosphorylation(GO:0016572)
0.1 0.3 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.9 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 0.9 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 1.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 0.4 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.5 GO:1901908 diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.1 0.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.6 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.6 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 0.2 GO:0035674 tricarboxylic acid transmembrane transport(GO:0035674)
0.1 1.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 0.2 GO:0014740 negative regulation of muscle hyperplasia(GO:0014740)
0.1 0.2 GO:0052314 terpene metabolic process(GO:0042214) phytoalexin metabolic process(GO:0052314)
0.1 0.2 GO:1902490 regulation of sperm capacitation(GO:1902490)
0.1 0.6 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.1 0.2 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930) lens fiber cell apoptotic process(GO:1990086)
0.1 0.2 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.1 0.5 GO:0002326 B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152)
0.1 1.5 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.3 GO:0003404 optic vesicle morphogenesis(GO:0003404) optic cup structural organization(GO:0003409)
0.1 0.4 GO:0071926 endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.2 GO:0098502 DNA dephosphorylation(GO:0098502)
0.1 0.3 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.2 GO:0071469 detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469)
0.1 0.3 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.1 0.4 GO:0060992 response to fungicide(GO:0060992)
0.1 0.4 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 0.2 GO:0044111 development involved in symbiotic interaction(GO:0044111)
0.1 0.2 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 2.5 GO:0006270 DNA replication initiation(GO:0006270)
0.1 0.3 GO:0097021 Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021)
0.1 0.2 GO:0021586 pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722)
0.1 0.3 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.0 0.1 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.3 GO:1904779 regulation of protein localization to centrosome(GO:1904779)
0.0 0.1 GO:1903526 negative regulation of membrane tubulation(GO:1903526)
0.0 0.1 GO:0031548 regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548)
0.0 0.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:0006422 aspartyl-tRNA aminoacylation(GO:0006422)
0.0 0.3 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.0 0.2 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.3 GO:0035672 oligopeptide transmembrane transport(GO:0035672)
0.0 0.3 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.0 0.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.3 GO:0032526 response to retinoic acid(GO:0032526)
0.0 0.2 GO:0097010 eukaryotic translation initiation factor 4F complex assembly(GO:0097010)
0.0 0.0 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
0.0 0.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.1 GO:1902723 negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723)
0.0 0.2 GO:0033387 putrescine biosynthetic process from ornithine(GO:0033387)
0.0 0.2 GO:0097527 necroptotic signaling pathway(GO:0097527)
0.0 0.9 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.2 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.4 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.1 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.4 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.0 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 1.9 GO:0050690 regulation of defense response to virus by virus(GO:0050690)
0.0 0.3 GO:0034465 response to carbon monoxide(GO:0034465)
0.0 0.3 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.6 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.3 GO:0000187 activation of MAPK activity(GO:0000187)
0.0 0.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.0 0.3 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0018094 protein polyglycylation(GO:0018094)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.1 GO:1904717 excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.2 GO:2000504 positive regulation of blood vessel remodeling(GO:2000504)
0.0 0.1 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.0 0.4 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.3 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.0 0.1 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397)
0.0 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:1902499 positive regulation of protein autoubiquitination(GO:1902499)
0.0 0.1 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.0 0.5 GO:0034162 toll-like receptor 9 signaling pathway(GO:0034162)
0.0 0.1 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.0 0.1 GO:0048149 behavioral response to ethanol(GO:0048149)
0.0 1.0 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
0.0 0.2 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.7 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:0002461 tolerance induction dependent upon immune response(GO:0002461)
0.0 0.1 GO:0071139 resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140)
0.0 0.1 GO:0019417 sulfur oxidation(GO:0019417)
0.0 0.4 GO:0010944 negative regulation of transcription by competitive promoter binding(GO:0010944)
0.0 0.1 GO:1903862 positive regulation of oxidative phosphorylation(GO:1903862)
0.0 0.2 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.2 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.0 0.2 GO:0000101 sulfur amino acid transport(GO:0000101)
0.0 0.2 GO:0036072 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.3 GO:0038007 netrin-activated signaling pathway(GO:0038007)
0.0 0.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.1 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.0 0.1 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.0 0.1 GO:0072675 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.1 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.0 0.2 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.0 0.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.1 GO:0051180 vitamin transport(GO:0051180)
0.0 0.5 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.0 0.2 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.5 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.0 0.3 GO:0051195 negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198)
0.0 0.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.3 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.0 GO:0046452 dihydrofolate metabolic process(GO:0046452)
0.0 0.4 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.1 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.2 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.2 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.2 GO:0033689 negative regulation of osteoblast proliferation(GO:0033689)
0.0 0.3 GO:0014029 neural crest formation(GO:0014029)
0.0 0.6 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.4 GO:0018298 protein-chromophore linkage(GO:0018298)
0.0 0.2 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.0 0.2 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:0071502 cellular response to temperature stimulus(GO:0071502)
0.0 0.1 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.1 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0060762 T-tubule organization(GO:0033292) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.2 GO:0045732 positive regulation of protein catabolic process(GO:0045732)
0.0 0.2 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.0 GO:0048203 vesicle targeting, trans-Golgi to endosome(GO:0048203)
0.0 0.2 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.0 0.1 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0061737 leukotriene signaling pathway(GO:0061737)
0.0 0.0 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.0 0.0 GO:0098905 regulation of bundle of His cell action potential(GO:0098905)
0.0 0.1 GO:0000432 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.0 0.2 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.0 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.1 GO:0002666 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) positive regulation of T cell tolerance induction(GO:0002666) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.2 GO:0002097 tRNA wobble base modification(GO:0002097)
0.0 0.0 GO:1900195 positive regulation of oocyte maturation(GO:1900195)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.0 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.0 GO:0010269 response to selenium ion(GO:0010269)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.3 GO:0097320 membrane tubulation(GO:0097320)
0.0 0.0 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.2 GO:0060576 intestinal epithelial cell development(GO:0060576)
0.0 0.1 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.4 GO:0030517 negative regulation of axon extension(GO:0030517)
0.0 0.5 GO:2000249 regulation of actin cytoskeleton reorganization(GO:2000249)
0.0 0.1 GO:2000535 regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.2 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0099515 vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515)
0.0 0.0 GO:0044211 CTP salvage(GO:0044211)
0.0 0.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0070762 nuclear pore transmembrane ring(GO:0070762)
0.5 0.5 GO:0097134 cyclin E1-CDK2 complex(GO:0097134)
0.2 0.8 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.2 0.9 GO:0070876 SOSS complex(GO:0070876)
0.1 1.0 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 2.5 GO:0045120 pronucleus(GO:0045120)
0.1 0.4 GO:0042565 RNA nuclear export complex(GO:0042565)
0.1 1.4 GO:0000796 condensin complex(GO:0000796)
0.1 0.5 GO:0000811 GINS complex(GO:0000811)
0.1 0.4 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.4 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.4 GO:0045160 myosin I complex(GO:0045160)
0.1 1.2 GO:0042555 MCM complex(GO:0042555)
0.1 0.5 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.4 GO:0045323 interleukin-1 receptor complex(GO:0045323)
0.1 0.2 GO:0035189 Rb-E2F complex(GO:0035189)
0.1 0.3 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.1 0.9 GO:0031209 SCAR complex(GO:0031209)
0.1 0.2 GO:0030936 collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936)
0.1 1.7 GO:0031011 Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202)
0.1 0.4 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 1.0 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.3 GO:0070435 Shc-EGFR complex(GO:0070435)
0.0 0.1 GO:0005668 RNA polymerase transcription factor SL1 complex(GO:0005668)
0.0 0.2 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.4 GO:0070852 cell body fiber(GO:0070852)
0.0 0.2 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 1.2 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 1.7 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 3.3 GO:0005901 caveola(GO:0005901)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.9 GO:0030669 clathrin-coated endocytic vesicle membrane(GO:0030669)
0.0 0.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.3 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.3 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0036449 microtubule minus-end(GO:0036449)
0.0 0.1 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 0.2 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.0 GO:0000125 PCAF complex(GO:0000125)
0.0 0.1 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.0 0.2 GO:0030914 STAGA complex(GO:0030914)
0.0 3.4 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.4 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.5 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0000346 transcription export complex(GO:0000346)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.0 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.5 GO:0030673 axolemma(GO:0030673)
0.0 1.4 GO:0060170 ciliary membrane(GO:0060170)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0071556 integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.0 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.0 0.2 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.3 GO:0042599 lamellar body(GO:0042599)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0043034 costamere(GO:0043034)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0050421 cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809)
0.5 1.5 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.4 1.1 GO:0015130 mevalonate transmembrane transporter activity(GO:0015130)
0.3 1.2 GO:0038025 reelin receptor activity(GO:0038025)
0.2 0.7 GO:0004347 glucose-6-phosphate isomerase activity(GO:0004347)
0.2 0.7 GO:0008859 exoribonuclease II activity(GO:0008859)
0.2 1.4 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 0.6 GO:0003883 CTP synthase activity(GO:0003883)
0.2 0.6 GO:0015235 cobalamin transporter activity(GO:0015235)
0.2 1.7 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2 0.6 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 0.7 GO:0004461 lactose synthase activity(GO:0004461)
0.2 0.5 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.4 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 3.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 0.4 GO:0090631 pre-miRNA transporter activity(GO:0090631)
0.1 0.9 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 1.8 GO:0035256 G-protein coupled glutamate receptor binding(GO:0035256)
0.1 0.5 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.6 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.4 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751)
0.1 0.9 GO:0043426 MRF binding(GO:0043426)
0.1 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.7 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.3 GO:0008457 beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256)
0.1 1.4 GO:0008179 adenylate cyclase binding(GO:0008179)
0.1 0.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.2 GO:0098782 mechanically-gated potassium channel activity(GO:0098782)
0.1 0.2 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.1 0.3 GO:0003985 acetyl-CoA C-acetyltransferase activity(GO:0003985)
0.1 0.5 GO:0000298 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848)
0.1 0.3 GO:0097677 STAT family protein binding(GO:0097677)
0.1 0.4 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.1 0.4 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.2 GO:0098518 polynucleotide phosphatase activity(GO:0098518)
0.1 0.2 GO:0000773 phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101)
0.1 0.6 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.2 GO:0033300 dehydroascorbic acid transporter activity(GO:0033300)
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.1 0.2 GO:0016534 cyclin-dependent protein kinase 5 activator activity(GO:0016534)
0.1 0.4 GO:0030621 U4 snRNA binding(GO:0030621)
0.1 0.2 GO:0070984 SET domain binding(GO:0070984)
0.1 1.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.1 0.6 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 0.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.3 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.5 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.5 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.2 GO:0070815 peptidyl-lysine 5-dioxygenase activity(GO:0070815)
0.0 1.7 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0016418 S-acetyltransferase activity(GO:0016418)
0.0 0.1 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.0 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.5 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.2 GO:0034057 RNA strand-exchange activity(GO:0034057)
0.0 0.2 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.2 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 1.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.2 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.7 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.2 GO:0043120 tumor necrosis factor binding(GO:0043120)
0.0 0.4 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.6 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.0 0.5 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.4 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.0 0.5 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.2 GO:0030151 molybdenum ion binding(GO:0030151)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.3 GO:0019211 phosphatase activator activity(GO:0019211)
0.0 0.2 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 1.1 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.2 GO:0070735 protein-glycine ligase activity(GO:0070735)
0.0 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0004815 aspartate-tRNA ligase activity(GO:0004815)
0.0 0.1 GO:0001632 leukotriene B4 receptor activity(GO:0001632)
0.0 0.4 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.4 GO:0008020 G-protein coupled photoreceptor activity(GO:0008020)
0.0 0.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.3 GO:0003910 DNA ligase (ATP) activity(GO:0003910)
0.0 0.6 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 1.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.7 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.2 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.2 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:0019206 nucleoside kinase activity(GO:0019206)
0.0 0.2 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.0 0.0 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0045182 translation regulator activity(GO:0045182)
0.0 0.1 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.1 GO:0004883 glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 0.1 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.4 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.0 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.8 GO:0019894 kinesin binding(GO:0019894)
0.0 0.2 GO:0004579 dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.4 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.3 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.0 GO:0022897 peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897)
0.0 0.0 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 1.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.3 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.3 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.2 GO:0005542 folic acid binding(GO:0005542)
0.0 0.1 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.2 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.2 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 SA_REG_CASCADE_OF_CYCLIN_EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.8 PID_RAC1_PATHWAY RAC1 signaling pathway
0.0 1.6 PID_S1P_S1P1_PATHWAY S1P1 pathway
0.0 1.4 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 3.3 PID_HIF1_TFPATHWAY HIF-1-alpha transcription factor network
0.0 1.8 PID_AURORA_B_PATHWAY Aurora B signaling
0.0 1.1 PID_P38_MK2_PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.8 PID_TOLL_ENDOGENOUS_PATHWAY Endogenous TLR signaling
0.0 1.9 PID_DELTA_NP63_PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 0.8 PID_NFKAPPAB_CANONICAL_PATHWAY Canonical NF-kappaB pathway
0.0 0.8 PID_ATR_PATHWAY ATR signaling pathway
0.0 0.4 PID_LPA4_PATHWAY LPA4-mediated signaling events
0.0 1.0 PID_HNF3B_PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.6 ST_GA12_PATHWAY G alpha 12 Pathway
0.0 0.5 PID_RETINOIC_ACID_PATHWAY Retinoic acid receptors-mediated signaling
0.0 1.2 PID_BCR_5PATHWAY BCR signaling pathway
0.0 0.8 PID_PLK1_PATHWAY PLK1 signaling events
0.0 0.5 PID_FOXM1_PATHWAY FOXM1 transcription factor network
0.0 0.5 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.3 PID_MYC_ACTIV_PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.2 0.3 REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.7 REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.1 1.7 REACTOME_UNWINDING_OF_DNA Genes involved in Unwinding of DNA
0.1 1.6 REACTOME_PURINE_SALVAGE Genes involved in Purine salvage
0.1 1.1 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 1.5 REACTOME_HDL_MEDIATED_LIPID_TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.2 REACTOME_PLATELET_SENSITIZATION_BY_LDL Genes involved in Platelet sensitization by LDL
0.0 0.7 REACTOME_IRAK1_RECRUITS_IKK_COMPLEX Genes involved in IRAK1 recruits IKK complex
0.0 0.6 REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.5 REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND Genes involved in Processive synthesis on the lagging strand
0.0 1.3 REACTOME_G0_AND_EARLY_G1 Genes involved in G0 and Early G1
0.0 0.7 REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE Genes involved in Reversible Hydration of Carbon Dioxide
0.0 0.5 REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.7 REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.9 REACTOME_SULFUR_AMINO_ACID_METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME_OPSINS Genes involved in Opsins
0.0 0.4 REACTOME_ANDROGEN_BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.6 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.8 REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.1 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 0.1 REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 2.2 REACTOME_MITOTIC_PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.8 REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.6 REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.3 REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.4 REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME_MICRORNA_MIRNA_BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.1 REACTOME_REGULATORY_RNA_PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.4 REACTOME_METABOLISM_OF_POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.6 REACTOME_G1_PHASE Genes involved in G1 Phase
0.0 0.1 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 0.2 REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.3 REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.2 REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.6 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.0 REACTOME_G1_S_SPECIFIC_TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.5 REACTOME_MRNA_3_END_PROCESSING Genes involved in mRNA 3'-end processing
0.0 1.0 REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE Genes involved in Late Phase of HIV Life Cycle