Motif ID: HES1
Z-value: 0.654
Transcription factors associated with HES1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
HES1 | ENSG00000114315.3 | HES1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
HES1 | hg19_v2_chr3_+_193853927_193853944 | 0.11 | 6.2e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 3.4 | GO:0046086 | adenosine biosynthetic process(GO:0046086) |
0.6 | 1.7 | GO:0036333 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
0.5 | 1.6 | GO:0071790 | spindle pole body duplication(GO:0030474) spindle pole body organization(GO:0051300) spindle pole body localization(GO:0070631) establishment of spindle pole body localization(GO:0070632) spindle pole body localization to nuclear envelope(GO:0071789) establishment of spindle pole body localization to nuclear envelope(GO:0071790) |
0.5 | 1.6 | GO:0006535 | cysteine biosynthetic process from serine(GO:0006535) |
0.5 | 1.5 | GO:0015920 | lipopolysaccharide transport(GO:0015920) |
0.5 | 1.8 | GO:0046102 | inosine metabolic process(GO:0046102) |
0.4 | 1.1 | GO:0051780 | mevalonate transport(GO:0015728) behavioral response to nutrient(GO:0051780) |
0.3 | 0.8 | GO:0035623 | regulation of pronephros size(GO:0035565) renal glucose absorption(GO:0035623) |
0.2 | 1.6 | GO:0007498 | mesoderm development(GO:0007498) |
0.2 | 0.7 | GO:0019242 | methylglyoxal biosynthetic process(GO:0019242) |
0.2 | 0.6 | GO:0044210 | 'de novo' CTP biosynthetic process(GO:0044210) |
0.2 | 0.6 | GO:0046521 | sphingoid catabolic process(GO:0046521) |
0.2 | 0.6 | GO:1903570 | regulation of protein kinase D signaling(GO:1903570) positive regulation of protein kinase D signaling(GO:1903572) |
0.2 | 0.6 | GO:0008355 | olfactory learning(GO:0008355) |
0.2 | 0.6 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
0.2 | 0.8 | GO:0003342 | proepicardium development(GO:0003342) septum transversum development(GO:0003343) |
0.2 | 0.5 | GO:0018153 | isopeptide cross-linking via N6-(L-isoglutamyl)-L-lysine(GO:0018153) isopeptide cross-linking(GO:0018262) |
0.2 | 0.2 | GO:0032808 | lacrimal gland development(GO:0032808) |
0.2 | 1.2 | GO:0038026 | reelin-mediated signaling pathway(GO:0038026) |
0.1 | 0.4 | GO:0034970 | histone H3-R2 methylation(GO:0034970) |
0.1 | 1.1 | GO:0000727 | double-strand break repair via break-induced replication(GO:0000727) |
0.1 | 0.4 | GO:0035281 | pre-miRNA export from nucleus(GO:0035281) |
0.1 | 0.7 | GO:0000738 | DNA catabolic process, exonucleolytic(GO:0000738) |
0.1 | 0.1 | GO:0043987 | regulation of histone phosphorylation(GO:0033127) positive regulation of histone phosphorylation(GO:0033129) histone-serine phosphorylation(GO:0035404) histone H3-S10 phosphorylation(GO:0043987) histone H3-S28 phosphorylation(GO:0043988) |
0.1 | 0.4 | GO:1901301 | regulation of cargo loading into COPII-coated vesicle(GO:1901301) |
0.1 | 0.5 | GO:0044314 | protein K27-linked ubiquitination(GO:0044314) |
0.1 | 0.4 | GO:0005988 | lactose metabolic process(GO:0005988) lactose biosynthetic process(GO:0005989) |
0.1 | 0.5 | GO:0046035 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
0.1 | 0.5 | GO:0046909 | intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445) |
0.1 | 1.2 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
0.1 | 0.7 | GO:0055064 | chloride ion homeostasis(GO:0055064) |
0.1 | 1.8 | GO:0060019 | radial glial cell differentiation(GO:0060019) |
0.1 | 0.6 | GO:0003430 | growth plate cartilage chondrocyte growth(GO:0003430) Harderian gland development(GO:0070384) |
0.1 | 0.4 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
0.1 | 0.1 | GO:2000857 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
0.1 | 1.7 | GO:0051639 | actin filament network formation(GO:0051639) |
0.1 | 0.4 | GO:0003308 | negative regulation of Wnt signaling pathway involved in heart development(GO:0003308) |
0.1 | 0.3 | GO:1900365 | positive regulation of mRNA polyadenylation(GO:1900365) positive regulation of apoptotic DNA fragmentation(GO:1902512) |
0.1 | 0.5 | GO:0010512 | negative regulation of phosphatidylinositol biosynthetic process(GO:0010512) |
0.1 | 0.4 | GO:1904694 | negative regulation of vascular smooth muscle contraction(GO:1904694) |
0.1 | 0.5 | GO:0072144 | glomerular mesangial cell development(GO:0072144) |
0.1 | 0.8 | GO:0070236 | negative regulation of activation-induced cell death of T cells(GO:0070236) |
0.1 | 0.4 | GO:0006287 | base-excision repair, gap-filling(GO:0006287) |
0.1 | 0.6 | GO:0021842 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) |
0.1 | 0.3 | GO:0016572 | histone phosphorylation(GO:0016572) |
0.1 | 0.3 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
0.1 | 0.9 | GO:2000601 | positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601) |
0.1 | 0.9 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) |
0.1 | 1.2 | GO:0010739 | positive regulation of protein kinase A signaling(GO:0010739) |
0.1 | 0.4 | GO:0032792 | negative regulation of CREB transcription factor activity(GO:0032792) |
0.1 | 0.5 | GO:1901908 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
0.1 | 0.3 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
0.1 | 0.6 | GO:0071494 | cellular response to UV-C(GO:0071494) |
0.1 | 0.6 | GO:0016560 | protein import into peroxisome matrix, docking(GO:0016560) |
0.1 | 0.2 | GO:0035674 | tricarboxylic acid transmembrane transport(GO:0035674) |
0.1 | 1.5 | GO:0007076 | mitotic chromosome condensation(GO:0007076) |
0.1 | 0.2 | GO:0014740 | negative regulation of muscle hyperplasia(GO:0014740) |
0.1 | 0.2 | GO:0052314 | terpene metabolic process(GO:0042214) phytoalexin metabolic process(GO:0052314) |
0.1 | 0.2 | GO:1902490 | regulation of sperm capacitation(GO:1902490) |
0.1 | 0.6 | GO:1904783 | positive regulation of NMDA glutamate receptor activity(GO:1904783) |
0.1 | 0.2 | GO:0071930 | negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930) lens fiber cell apoptotic process(GO:1990086) |
0.1 | 0.2 | GO:0007206 | phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206) |
0.1 | 0.5 | GO:0002326 | B cell lineage commitment(GO:0002326) immunoglobulin V(D)J recombination(GO:0033152) |
0.1 | 1.5 | GO:0007216 | G-protein coupled glutamate receptor signaling pathway(GO:0007216) |
0.1 | 0.3 | GO:0003404 | optic vesicle morphogenesis(GO:0003404) optic cup structural organization(GO:0003409) |
0.1 | 0.4 | GO:0071926 | endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124) |
0.1 | 0.2 | GO:0098502 | DNA dephosphorylation(GO:0098502) |
0.1 | 0.3 | GO:0031296 | B cell costimulation(GO:0031296) |
0.1 | 0.2 | GO:0071469 | detection of mechanical stimulus involved in sensory perception of touch(GO:0050976) cellular response to alkaline pH(GO:0071469) |
0.1 | 0.3 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
0.1 | 0.4 | GO:0060992 | response to fungicide(GO:0060992) |
0.1 | 0.4 | GO:1900748 | positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748) |
0.1 | 0.2 | GO:0044111 | development involved in symbiotic interaction(GO:0044111) |
0.1 | 0.2 | GO:0021526 | medial motor column neuron differentiation(GO:0021526) |
0.1 | 2.5 | GO:0006270 | DNA replication initiation(GO:0006270) |
0.1 | 0.3 | GO:0097021 | Peyer's patch morphogenesis(GO:0061146) lymphocyte migration into lymphoid organs(GO:0097021) |
0.1 | 0.2 | GO:0021586 | pons maturation(GO:0021586) superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722) |
0.1 | 0.3 | GO:0033567 | DNA replication, Okazaki fragment processing(GO:0033567) |
0.0 | 0.1 | GO:2001226 | negative regulation of chloride transport(GO:2001226) |
0.0 | 0.3 | GO:0032483 | regulation of Rab protein signal transduction(GO:0032483) |
0.0 | 0.1 | GO:0021555 | midbrain-hindbrain boundary morphogenesis(GO:0021555) |
0.0 | 0.3 | GO:1904779 | regulation of protein localization to centrosome(GO:1904779) |
0.0 | 0.1 | GO:1903526 | negative regulation of membrane tubulation(GO:1903526) |
0.0 | 0.1 | GO:0031548 | regulation of brain-derived neurotrophic factor receptor signaling pathway(GO:0031548) |
0.0 | 0.4 | GO:0046604 | positive regulation of mitotic centrosome separation(GO:0046604) |
0.0 | 0.1 | GO:0006422 | aspartyl-tRNA aminoacylation(GO:0006422) |
0.0 | 0.3 | GO:0021937 | cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937) |
0.0 | 0.2 | GO:2001295 | malonyl-CoA biosynthetic process(GO:2001295) |
0.0 | 0.3 | GO:0035672 | oligopeptide transmembrane transport(GO:0035672) |
0.0 | 0.3 | GO:0035965 | cardiolipin acyl-chain remodeling(GO:0035965) |
0.0 | 0.2 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
0.0 | 0.3 | GO:0032526 | response to retinoic acid(GO:0032526) |
0.0 | 0.2 | GO:0097010 | eukaryotic translation initiation factor 4F complex assembly(GO:0097010) |
0.0 | 0.0 | GO:2000313 | fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) |
0.0 | 0.3 | GO:0070345 | negative regulation of fat cell proliferation(GO:0070345) |
0.0 | 0.1 | GO:1902723 | negative regulation of skeletal muscle cell proliferation(GO:0014859) negative regulation of skeletal muscle satellite cell proliferation(GO:1902723) |
0.0 | 0.2 | GO:0033387 | putrescine biosynthetic process from ornithine(GO:0033387) |
0.0 | 0.2 | GO:0097527 | necroptotic signaling pathway(GO:0097527) |
0.0 | 0.9 | GO:0070208 | protein heterotrimerization(GO:0070208) |
0.0 | 0.2 | GO:0010793 | regulation of mRNA export from nucleus(GO:0010793) |
0.0 | 0.2 | GO:0002159 | desmosome assembly(GO:0002159) |
0.0 | 0.4 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.0 | 0.1 | GO:0002188 | translation reinitiation(GO:0002188) |
0.0 | 0.1 | GO:0032072 | plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072) |
0.0 | 0.4 | GO:0033313 | meiotic cell cycle checkpoint(GO:0033313) |
0.0 | 0.2 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
0.0 | 1.9 | GO:0050690 | regulation of defense response to virus by virus(GO:0050690) |
0.0 | 0.3 | GO:0034465 | response to carbon monoxide(GO:0034465) |
0.0 | 0.3 | GO:0006189 | 'de novo' IMP biosynthetic process(GO:0006189) |
0.0 | 0.6 | GO:0007252 | I-kappaB phosphorylation(GO:0007252) |
0.0 | 0.2 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
0.0 | 0.5 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
0.0 | 0.2 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
0.0 | 0.3 | GO:0000187 | activation of MAPK activity(GO:0000187) |
0.0 | 0.4 | GO:0000463 | maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463) |
0.0 | 0.3 | GO:0045040 | protein import into mitochondrial outer membrane(GO:0045040) |
0.0 | 0.2 | GO:0018094 | protein polyglycylation(GO:0018094) |
0.0 | 0.1 | GO:0002949 | tRNA threonylcarbamoyladenosine modification(GO:0002949) |
0.0 | 0.1 | GO:1904717 | excitatory chemical synaptic transmission(GO:0098976) regulation of AMPA glutamate receptor clustering(GO:1904717) positive regulation of AMPA glutamate receptor clustering(GO:1904719) |
0.0 | 0.2 | GO:2000504 | positive regulation of blood vessel remodeling(GO:2000504) |
0.0 | 0.1 | GO:1904751 | positive regulation of protein localization to nucleolus(GO:1904751) |
0.0 | 0.4 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
0.0 | 0.3 | GO:1903243 | negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243) |
0.0 | 0.1 | GO:0043397 | corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) |
0.0 | 0.3 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.0 | 0.1 | GO:1902499 | positive regulation of protein autoubiquitination(GO:1902499) |
0.0 | 0.1 | GO:0002143 | tRNA wobble position uridine thiolation(GO:0002143) |
0.0 | 0.5 | GO:0034162 | toll-like receptor 9 signaling pathway(GO:0034162) |
0.0 | 0.1 | GO:0014707 | branchiomeric skeletal muscle development(GO:0014707) |
0.0 | 0.1 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
0.0 | 1.0 | GO:0072698 | protein localization to microtubule cytoskeleton(GO:0072698) |
0.0 | 0.2 | GO:1902416 | positive regulation of mRNA binding(GO:1902416) |
0.0 | 0.7 | GO:0051290 | protein heterotetramerization(GO:0051290) |
0.0 | 0.1 | GO:0002461 | tolerance induction dependent upon immune response(GO:0002461) |
0.0 | 0.1 | GO:0071139 | resolution of recombination intermediates(GO:0071139) resolution of mitotic recombination intermediates(GO:0071140) |
0.0 | 0.1 | GO:0019417 | sulfur oxidation(GO:0019417) |
0.0 | 0.4 | GO:0010944 | negative regulation of transcription by competitive promoter binding(GO:0010944) |
0.0 | 0.1 | GO:1903862 | positive regulation of oxidative phosphorylation(GO:1903862) |
0.0 | 0.2 | GO:0031022 | nuclear migration along microfilament(GO:0031022) |
0.0 | 0.2 | GO:0035087 | siRNA loading onto RISC involved in RNA interference(GO:0035087) |
0.0 | 0.2 | GO:0000101 | sulfur amino acid transport(GO:0000101) |
0.0 | 0.2 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
0.0 | 0.3 | GO:0038007 | netrin-activated signaling pathway(GO:0038007) |
0.0 | 0.4 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
0.0 | 0.1 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
0.0 | 0.1 | GO:0000379 | tRNA-type intron splice site recognition and cleavage(GO:0000379) |
0.0 | 0.1 | GO:0072675 | multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675) |
0.0 | 0.1 | GO:0007023 | post-chaperonin tubulin folding pathway(GO:0007023) |
0.0 | 0.1 | GO:0021521 | ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573) |
0.0 | 0.1 | GO:1904529 | regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616) |
0.0 | 0.2 | GO:0006002 | fructose 6-phosphate metabolic process(GO:0006002) |
0.0 | 0.1 | GO:0006041 | glucosamine metabolic process(GO:0006041) |
0.0 | 0.1 | GO:0051180 | vitamin transport(GO:0051180) |
0.0 | 0.5 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
0.0 | 0.2 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
0.0 | 0.5 | GO:0042921 | glucocorticoid receptor signaling pathway(GO:0042921) |
0.0 | 0.3 | GO:0051195 | negative regulation of glycolytic process(GO:0045820) negative regulation of cofactor metabolic process(GO:0051195) negative regulation of coenzyme metabolic process(GO:0051198) |
0.0 | 0.7 | GO:0045662 | negative regulation of myoblast differentiation(GO:0045662) |
0.0 | 0.1 | GO:0014063 | negative regulation of serotonin secretion(GO:0014063) |
0.0 | 0.3 | GO:0002115 | store-operated calcium entry(GO:0002115) |
0.0 | 0.3 | GO:0046784 | viral mRNA export from host cell nucleus(GO:0046784) |
0.0 | 0.0 | GO:0046452 | dihydrofolate metabolic process(GO:0046452) |
0.0 | 0.4 | GO:0040015 | negative regulation of multicellular organism growth(GO:0040015) |
0.0 | 0.1 | GO:0007198 | adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) |
0.0 | 0.1 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
0.0 | 0.2 | GO:0002051 | osteoblast fate commitment(GO:0002051) |
0.0 | 0.1 | GO:0030200 | heparan sulfate proteoglycan catabolic process(GO:0030200) |
0.0 | 0.2 | GO:1904322 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
0.0 | 0.2 | GO:0033689 | negative regulation of osteoblast proliferation(GO:0033689) |
0.0 | 0.3 | GO:0014029 | neural crest formation(GO:0014029) |
0.0 | 0.6 | GO:0021680 | cerebellar Purkinje cell layer development(GO:0021680) |
0.0 | 0.4 | GO:0018298 | protein-chromophore linkage(GO:0018298) |
0.0 | 0.2 | GO:0050747 | positive regulation of lipoprotein metabolic process(GO:0050747) |
0.0 | 0.2 | GO:2000049 | positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049) |
0.0 | 0.1 | GO:0071502 | cellular response to temperature stimulus(GO:0071502) |
0.0 | 0.1 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
0.0 | 0.1 | GO:0003433 | chondrocyte development involved in endochondral bone morphogenesis(GO:0003433) |
0.0 | 0.2 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
0.0 | 0.1 | GO:0060762 | T-tubule organization(GO:0033292) regulation of branching involved in mammary gland duct morphogenesis(GO:0060762) positive regulation of caveolin-mediated endocytosis(GO:2001288) |
0.0 | 0.0 | GO:0006428 | isoleucyl-tRNA aminoacylation(GO:0006428) |
0.0 | 0.2 | GO:0045732 | positive regulation of protein catabolic process(GO:0045732) |
0.0 | 0.2 | GO:0006777 | Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720) |
0.0 | 0.0 | GO:0048203 | vesicle targeting, trans-Golgi to endosome(GO:0048203) |
0.0 | 0.2 | GO:1904263 | positive regulation of TORC1 signaling(GO:1904263) |
0.0 | 0.1 | GO:0043696 | dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697) |
0.0 | 0.2 | GO:0019532 | oxalate transport(GO:0019532) |
0.0 | 0.2 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
0.0 | 0.1 | GO:0060800 | regulation of cell differentiation involved in embryonic placenta development(GO:0060800) |
0.0 | 0.1 | GO:0061737 | leukotriene signaling pathway(GO:0061737) |
0.0 | 0.0 | GO:2000583 | regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584) |
0.0 | 0.0 | GO:0098905 | regulation of bundle of His cell action potential(GO:0098905) |
0.0 | 0.1 | GO:0000432 | regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) |
0.0 | 0.2 | GO:0001574 | ganglioside biosynthetic process(GO:0001574) |
0.0 | 0.0 | GO:1904933 | regulation of cell proliferation in midbrain(GO:1904933) |
0.0 | 0.2 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
0.0 | 0.0 | GO:2000182 | regulation of progesterone biosynthetic process(GO:2000182) |
0.0 | 0.1 | GO:0002666 | antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480) positive regulation of T cell tolerance induction(GO:0002666) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767) |
0.0 | 0.1 | GO:0060770 | negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770) |
0.0 | 0.2 | GO:0002097 | tRNA wobble base modification(GO:0002097) |
0.0 | 0.0 | GO:1900195 | positive regulation of oocyte maturation(GO:1900195) |
0.0 | 0.1 | GO:0016557 | peroxisome membrane biogenesis(GO:0016557) |
0.0 | 0.2 | GO:0033234 | negative regulation of protein sumoylation(GO:0033234) |
0.0 | 0.0 | GO:0061198 | fungiform papilla formation(GO:0061198) |
0.0 | 0.0 | GO:0010269 | response to selenium ion(GO:0010269) |
0.0 | 0.1 | GO:0006931 | substrate-dependent cell migration, cell attachment to substrate(GO:0006931) |
0.0 | 0.3 | GO:0097320 | membrane tubulation(GO:0097320) |
0.0 | 0.0 | GO:0007037 | vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830) |
0.0 | 0.1 | GO:0006384 | transcription initiation from RNA polymerase III promoter(GO:0006384) |
0.0 | 0.2 | GO:0060576 | intestinal epithelial cell development(GO:0060576) |
0.0 | 0.1 | GO:0048842 | positive regulation of axon extension involved in axon guidance(GO:0048842) |
0.0 | 0.4 | GO:0030517 | negative regulation of axon extension(GO:0030517) |
0.0 | 0.5 | GO:2000249 | regulation of actin cytoskeleton reorganization(GO:2000249) |
0.0 | 0.1 | GO:2000535 | regulation of entry of bacterium into host cell(GO:2000535) |
0.0 | 0.2 | GO:0007213 | G-protein coupled acetylcholine receptor signaling pathway(GO:0007213) |
0.0 | 0.1 | GO:0000722 | telomere maintenance via recombination(GO:0000722) |
0.0 | 0.1 | GO:0099515 | vesicle transport along actin filament(GO:0030050) actin filament-based transport(GO:0099515) |
0.0 | 0.0 | GO:0044211 | CTP salvage(GO:0044211) |
0.0 | 0.7 | GO:0018279 | protein N-linked glycosylation via asparagine(GO:0018279) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.6 | GO:0070762 | nuclear pore transmembrane ring(GO:0070762) |
0.5 | 0.5 | GO:0097134 | cyclin E1-CDK2 complex(GO:0097134) |
0.2 | 0.8 | GO:0097135 | cyclin E2-CDK2 complex(GO:0097135) |
0.2 | 0.9 | GO:0070876 | SOSS complex(GO:0070876) |
0.1 | 1.0 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
0.1 | 2.5 | GO:0045120 | pronucleus(GO:0045120) |
0.1 | 0.4 | GO:0042565 | RNA nuclear export complex(GO:0042565) |
0.1 | 1.4 | GO:0000796 | condensin complex(GO:0000796) |
0.1 | 0.5 | GO:0000811 | GINS complex(GO:0000811) |
0.1 | 0.4 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
0.1 | 0.4 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
0.1 | 0.4 | GO:0033186 | CAF-1 complex(GO:0033186) |
0.1 | 0.4 | GO:0045160 | myosin I complex(GO:0045160) |
0.1 | 1.2 | GO:0042555 | MCM complex(GO:0042555) |
0.1 | 0.5 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
0.1 | 0.4 | GO:0045323 | interleukin-1 receptor complex(GO:0045323) |
0.1 | 0.2 | GO:0035189 | Rb-E2F complex(GO:0035189) |
0.1 | 0.3 | GO:0043625 | delta DNA polymerase complex(GO:0043625) |
0.1 | 0.9 | GO:0031209 | SCAR complex(GO:0031209) |
0.1 | 0.2 | GO:0030936 | collagen type XIII trimer(GO:0005600) transmembrane collagen trimer(GO:0030936) |
0.1 | 1.7 | GO:0031011 | Ino80 complex(GO:0031011) DNA helicase complex(GO:0033202) |
0.1 | 0.4 | GO:0070545 | PeBoW complex(GO:0070545) |
0.1 | 0.5 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
0.0 | 1.0 | GO:0097431 | mitotic spindle pole(GO:0097431) |
0.0 | 0.8 | GO:0008385 | IkappaB kinase complex(GO:0008385) |
0.0 | 0.3 | GO:0070435 | Shc-EGFR complex(GO:0070435) |
0.0 | 0.1 | GO:0005668 | RNA polymerase transcription factor SL1 complex(GO:0005668) |
0.0 | 0.2 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
0.0 | 0.4 | GO:0070852 | cell body fiber(GO:0070852) |
0.0 | 0.2 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
0.0 | 0.1 | GO:0005967 | mitochondrial pyruvate dehydrogenase complex(GO:0005967) |
0.0 | 1.2 | GO:0032839 | dendrite cytoplasm(GO:0032839) |
0.0 | 0.2 | GO:0042719 | mitochondrial intermembrane space protein transporter complex(GO:0042719) |
0.0 | 1.7 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.0 | 0.2 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
0.0 | 0.2 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
0.0 | 3.3 | GO:0005901 | caveola(GO:0005901) |
0.0 | 0.4 | GO:0035102 | PRC1 complex(GO:0035102) |
0.0 | 0.7 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 1.9 | GO:0030669 | clathrin-coated endocytic vesicle membrane(GO:0030669) |
0.0 | 0.4 | GO:0005847 | mRNA cleavage and polyadenylation specificity factor complex(GO:0005847) |
0.0 | 0.1 | GO:0035061 | interchromatin granule(GO:0035061) |
0.0 | 0.2 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 0.3 | GO:0005811 | lipid particle(GO:0005811) |
0.0 | 0.2 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 0.3 | GO:0098799 | outer mitochondrial membrane protein complex(GO:0098799) |
0.0 | 0.3 | GO:0061700 | GATOR2 complex(GO:0061700) |
0.0 | 0.2 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.0 | 0.1 | GO:0036449 | microtubule minus-end(GO:0036449) |
0.0 | 0.1 | GO:0000214 | tRNA-intron endonuclease complex(GO:0000214) |
0.0 | 0.2 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
0.0 | 0.1 | GO:0031417 | NatC complex(GO:0031417) |
0.0 | 0.4 | GO:1990124 | messenger ribonucleoprotein complex(GO:1990124) |
0.0 | 0.0 | GO:0000125 | PCAF complex(GO:0000125) |
0.0 | 0.1 | GO:0001405 | presequence translocase-associated import motor(GO:0001405) |
0.0 | 0.2 | GO:0030914 | STAGA complex(GO:0030914) |
0.0 | 3.4 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 1.4 | GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116) |
0.0 | 0.5 | GO:0005682 | U5 snRNP(GO:0005682) |
0.0 | 0.9 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
0.0 | 0.4 | GO:0005852 | eukaryotic translation initiation factor 3 complex(GO:0005852) |
0.0 | 0.5 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
0.0 | 0.3 | GO:0000346 | transcription export complex(GO:0000346) |
0.0 | 0.3 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.0 | 0.3 | GO:0005671 | Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671) |
0.0 | 0.3 | GO:0033391 | chromatoid body(GO:0033391) |
0.0 | 0.0 | GO:0031372 | UBC13-MMS2 complex(GO:0031372) |
0.0 | 0.1 | GO:0005672 | transcription factor TFIIA complex(GO:0005672) |
0.0 | 0.1 | GO:0042765 | GPI-anchor transamidase complex(GO:0042765) |
0.0 | 0.5 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 1.4 | GO:0060170 | ciliary membrane(GO:0060170) |
0.0 | 0.5 | GO:0000314 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
0.0 | 0.1 | GO:0071556 | integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553) |
0.0 | 0.5 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.0 | 0.1 | GO:0032584 | growth cone membrane(GO:0032584) |
0.0 | 0.0 | GO:0071204 | histone pre-mRNA 3'end processing complex(GO:0071204) |
0.0 | 0.2 | GO:0045009 | melanosome membrane(GO:0033162) chitosome(GO:0045009) |
0.0 | 0.2 | GO:0031045 | dense core granule(GO:0031045) |
0.0 | 0.3 | GO:0042599 | lamellar body(GO:0042599) |
0.0 | 0.2 | GO:0001673 | male germ cell nucleus(GO:0001673) |
0.0 | 0.1 | GO:0033263 | CORVET complex(GO:0033263) |
0.0 | 0.2 | GO:0008250 | oligosaccharyltransferase complex(GO:0008250) |
0.0 | 0.2 | GO:0043034 | costamere(GO:0043034) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.5 | 1.6 | GO:0050421 | cystathionine beta-synthase activity(GO:0004122) oxidoreductase activity, acting on other nitrogenous compounds as donors, cytochrome as acceptor(GO:0016662) nitrite reductase (NO-forming) activity(GO:0050421) carbon monoxide binding(GO:0070025) nitrite reductase activity(GO:0098809) |
0.5 | 1.5 | GO:0070506 | high-density lipoprotein particle receptor activity(GO:0070506) |
0.4 | 1.1 | GO:0015130 | mevalonate transmembrane transporter activity(GO:0015130) |
0.3 | 1.2 | GO:0038025 | reelin receptor activity(GO:0038025) |
0.2 | 0.7 | GO:0004347 | glucose-6-phosphate isomerase activity(GO:0004347) |
0.2 | 0.7 | GO:0008859 | exoribonuclease II activity(GO:0008859) |
0.2 | 1.4 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
0.2 | 0.6 | GO:0003883 | CTP synthase activity(GO:0003883) |
0.2 | 0.6 | GO:0015235 | cobalamin transporter activity(GO:0015235) |
0.2 | 1.7 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.2 | 0.6 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
0.2 | 0.7 | GO:0004461 | lactose synthase activity(GO:0004461) |
0.2 | 0.5 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
0.1 | 0.4 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
0.1 | 3.1 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
0.1 | 0.4 | GO:0090631 | pre-miRNA transporter activity(GO:0090631) |
0.1 | 0.9 | GO:0015526 | hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513) |
0.1 | 1.8 | GO:0035256 | G-protein coupled glutamate receptor binding(GO:0035256) |
0.1 | 0.5 | GO:0070644 | vitamin D response element binding(GO:0070644) |
0.1 | 0.6 | GO:0017050 | sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050) |
0.1 | 0.4 | GO:0047751 | 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765) cholestenone 5-alpha-reductase activity(GO:0047751) |
0.1 | 0.9 | GO:0043426 | MRF binding(GO:0043426) |
0.1 | 0.5 | GO:0043183 | vascular endothelial growth factor receptor 1 binding(GO:0043183) |
0.1 | 0.7 | GO:0005087 | Ran guanyl-nucleotide exchange factor activity(GO:0005087) |
0.1 | 0.3 | GO:0008457 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
0.1 | 1.4 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
0.1 | 0.6 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
0.1 | 1.4 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
0.1 | 0.2 | GO:0098782 | mechanically-gated potassium channel activity(GO:0098782) |
0.1 | 0.2 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
0.1 | 0.3 | GO:0003985 | acetyl-CoA C-acetyltransferase activity(GO:0003985) |
0.1 | 0.5 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
0.1 | 0.3 | GO:0097677 | STAT family protein binding(GO:0097677) |
0.1 | 0.4 | GO:0016428 | tRNA (cytosine-5-)-methyltransferase activity(GO:0016428) |
0.1 | 0.4 | GO:0008269 | JAK pathway signal transduction adaptor activity(GO:0008269) |
0.1 | 0.2 | GO:0098518 | polynucleotide phosphatase activity(GO:0098518) |
0.1 | 0.2 | GO:0000773 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
0.1 | 0.6 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
0.1 | 0.2 | GO:0033300 | dehydroascorbic acid transporter activity(GO:0033300) |
0.1 | 0.2 | GO:0098808 | mRNA cap binding(GO:0098808) |
0.1 | 0.2 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
0.1 | 0.4 | GO:0030621 | U4 snRNA binding(GO:0030621) |
0.1 | 0.2 | GO:0070984 | SET domain binding(GO:0070984) |
0.1 | 1.6 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
0.1 | 0.6 | GO:0046703 | natural killer cell lectin-like receptor binding(GO:0046703) |
0.1 | 0.6 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
0.0 | 0.1 | GO:0008330 | protein tyrosine/threonine phosphatase activity(GO:0008330) |
0.0 | 0.3 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.0 | 0.5 | GO:0004704 | NF-kappaB-inducing kinase activity(GO:0004704) |
0.0 | 0.5 | GO:0004849 | uridine kinase activity(GO:0004849) |
0.0 | 0.2 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
0.0 | 1.7 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
0.0 | 0.1 | GO:0016418 | S-acetyltransferase activity(GO:0016418) |
0.0 | 0.1 | GO:0000026 | alpha-1,2-mannosyltransferase activity(GO:0000026) |
0.0 | 0.2 | GO:0003989 | acetyl-CoA carboxylase activity(GO:0003989) |
0.0 | 0.4 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
0.0 | 0.1 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
0.0 | 0.5 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
0.0 | 0.2 | GO:0034057 | RNA strand-exchange activity(GO:0034057) |
0.0 | 0.2 | GO:0003872 | 6-phosphofructokinase activity(GO:0003872) |
0.0 | 0.2 | GO:0001010 | transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010) |
0.0 | 0.2 | GO:0034617 | tetrahydrobiopterin binding(GO:0034617) |
0.0 | 1.3 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 0.2 | GO:0051032 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
0.0 | 0.7 | GO:0004089 | carbonate dehydratase activity(GO:0004089) |
0.0 | 0.3 | GO:0060072 | large conductance calcium-activated potassium channel activity(GO:0060072) |
0.0 | 0.2 | GO:0043120 | tumor necrosis factor binding(GO:0043120) |
0.0 | 0.4 | GO:0035242 | protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242) |
0.0 | 0.1 | GO:0098770 | FBXO family protein binding(GO:0098770) |
0.0 | 0.6 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
0.0 | 0.2 | GO:0015142 | citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142) |
0.0 | 0.3 | GO:0048408 | epidermal growth factor binding(GO:0048408) |
0.0 | 0.5 | GO:0004723 | calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) |
0.0 | 0.4 | GO:0001042 | RNA polymerase I core binding(GO:0001042) |
0.0 | 0.5 | GO:0048407 | platelet-derived growth factor binding(GO:0048407) |
0.0 | 0.3 | GO:1901612 | cardiolipin binding(GO:1901612) |
0.0 | 0.2 | GO:0030151 | molybdenum ion binding(GO:0030151) |
0.0 | 0.2 | GO:0050733 | RS domain binding(GO:0050733) |
0.0 | 0.3 | GO:0019211 | phosphatase activator activity(GO:0019211) |
0.0 | 0.2 | GO:0016316 | phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) |
0.0 | 0.1 | GO:0030976 | thiamine pyrophosphate binding(GO:0030976) |
0.0 | 1.1 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
0.0 | 0.1 | GO:0004692 | cGMP-dependent protein kinase activity(GO:0004692) |
0.0 | 0.2 | GO:0070735 | protein-glycine ligase activity(GO:0070735) |
0.0 | 0.6 | GO:0008432 | JUN kinase binding(GO:0008432) |
0.0 | 0.6 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.1 | GO:0000405 | bubble DNA binding(GO:0000405) |
0.0 | 0.1 | GO:0004815 | aspartate-tRNA ligase activity(GO:0004815) |
0.0 | 0.1 | GO:0001632 | leukotriene B4 receptor activity(GO:0001632) |
0.0 | 0.4 | GO:0008140 | cAMP response element binding protein binding(GO:0008140) |
0.0 | 0.4 | GO:0008020 | G-protein coupled photoreceptor activity(GO:0008020) |
0.0 | 0.5 | GO:0043138 | 3'-5' DNA helicase activity(GO:0043138) |
0.0 | 0.3 | GO:0003910 | DNA ligase (ATP) activity(GO:0003910) |
0.0 | 0.6 | GO:0004383 | guanylate cyclase activity(GO:0004383) |
0.0 | 1.0 | GO:0016538 | cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538) |
0.0 | 0.7 | GO:0046965 | retinoid X receptor binding(GO:0046965) |
0.0 | 0.4 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.0 | 0.1 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.0 | 0.2 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
0.0 | 0.2 | GO:0000099 | sulfur amino acid transmembrane transporter activity(GO:0000099) |
0.0 | 0.2 | GO:0030306 | ADP-ribosylation factor binding(GO:0030306) |
0.0 | 0.2 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
0.0 | 0.3 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.0 | 0.2 | GO:0086083 | cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083) |
0.0 | 0.1 | GO:0048403 | brain-derived neurotrophic factor binding(GO:0048403) |
0.0 | 0.2 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
0.0 | 0.3 | GO:0019206 | nucleoside kinase activity(GO:0019206) |
0.0 | 0.2 | GO:1990380 | Lys48-specific deubiquitinase activity(GO:1990380) |
0.0 | 0.2 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.0 | 0.1 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
0.0 | 0.4 | GO:0035259 | glucocorticoid receptor binding(GO:0035259) |
0.0 | 0.2 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.0 | 0.3 | GO:0015279 | store-operated calcium channel activity(GO:0015279) |
0.0 | 0.3 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
0.0 | 0.0 | GO:0004822 | isoleucine-tRNA ligase activity(GO:0004822) |
0.0 | 0.1 | GO:0008431 | vitamin E binding(GO:0008431) |
0.0 | 0.2 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
0.0 | 0.1 | GO:0045182 | translation regulator activity(GO:0045182) |
0.0 | 0.1 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) |
0.0 | 0.4 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.0 | 0.1 | GO:0004883 | glucocorticoid receptor activity(GO:0004883) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
0.0 | 0.1 | GO:0038052 | RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052) |
0.0 | 0.1 | GO:0016861 | intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861) |
0.0 | 0.2 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
0.0 | 0.4 | GO:0001056 | RNA polymerase III activity(GO:0001056) |
0.0 | 0.1 | GO:0016176 | superoxide-generating NADPH oxidase activator activity(GO:0016176) |
0.0 | 0.0 | GO:0015173 | aromatic amino acid transmembrane transporter activity(GO:0015173) |
0.0 | 0.8 | GO:0019894 | kinesin binding(GO:0019894) |
0.0 | 0.2 | GO:0004579 | dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579) |
0.0 | 0.4 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.0 | 0.3 | GO:0070300 | phosphatidic acid binding(GO:0070300) |
0.0 | 0.1 | GO:0071535 | RING-like zinc finger domain binding(GO:0071535) |
0.0 | 0.1 | GO:0003923 | GPI-anchor transamidase activity(GO:0003923) |
0.0 | 0.3 | GO:0016881 | acid-amino acid ligase activity(GO:0016881) |
0.0 | 0.2 | GO:0004526 | ribonuclease P activity(GO:0004526) |
0.0 | 0.0 | GO:0022897 | peptide:proton symporter activity(GO:0015333) proton-dependent peptide secondary active transmembrane transporter activity(GO:0022897) |
0.0 | 0.0 | GO:0071207 | histone pre-mRNA stem-loop binding(GO:0071207) |
0.0 | 0.5 | GO:0051959 | dynein light intermediate chain binding(GO:0051959) |
0.0 | 0.2 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.0 | 1.7 | GO:0008565 | protein transporter activity(GO:0008565) |
0.0 | 0.4 | GO:0031369 | translation initiation factor binding(GO:0031369) |
0.0 | 0.1 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
0.0 | 0.3 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
0.0 | 0.3 | GO:0004707 | MAP kinase activity(GO:0004707) |
0.0 | 0.2 | GO:0005542 | folic acid binding(GO:0005542) |
0.0 | 0.1 | GO:0005332 | gamma-aminobutyric acid:sodium symporter activity(GO:0005332) |
0.0 | 0.2 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
0.0 | 0.1 | GO:0035197 | siRNA binding(GO:0035197) |
0.0 | 0.2 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
0.0 | 0.2 | GO:0001206 | transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206) |
0.0 | 0.0 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
0.0 | 0.1 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
0.0 | 0.4 | GO:0017025 | TBP-class protein binding(GO:0017025) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.5 | SA_REG_CASCADE_OF_CYCLIN_EXPR | Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases. |
0.0 | 0.8 | PID_RAC1_PATHWAY | RAC1 signaling pathway |
0.0 | 1.6 | PID_S1P_S1P1_PATHWAY | S1P1 pathway |
0.0 | 1.4 | PID_LIS1_PATHWAY | Lissencephaly gene (LIS1) in neuronal migration and development |
0.0 | 3.3 | PID_HIF1_TFPATHWAY | HIF-1-alpha transcription factor network |
0.0 | 1.8 | PID_AURORA_B_PATHWAY | Aurora B signaling |
0.0 | 1.1 | PID_P38_MK2_PATHWAY | p38 signaling mediated by MAPKAP kinases |
0.0 | 0.8 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.0 | 1.9 | PID_DELTA_NP63_PATHWAY | Validated transcriptional targets of deltaNp63 isoforms |
0.0 | 0.8 | PID_NFKAPPAB_CANONICAL_PATHWAY | Canonical NF-kappaB pathway |
0.0 | 0.8 | PID_ATR_PATHWAY | ATR signaling pathway |
0.0 | 0.4 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.0 | 1.0 | PID_HNF3B_PATHWAY | FOXA2 and FOXA3 transcription factor networks |
0.0 | 0.5 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.0 | 0.6 | ST_GA12_PATHWAY | G alpha 12 Pathway |
0.0 | 0.5 | PID_RETINOIC_ACID_PATHWAY | Retinoic acid receptors-mediated signaling |
0.0 | 1.2 | PID_BCR_5PATHWAY | BCR signaling pathway |
0.0 | 0.8 | PID_PLK1_PATHWAY | PLK1 signaling events |
0.0 | 0.5 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.0 | 0.5 | PID_FRA_PATHWAY | Validated transcriptional targets of AP1 family members Fra1 and Fra2 |
0.0 | 1.3 | PID_MYC_ACTIV_PATHWAY | Validated targets of C-MYC transcriptional activation |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 3.6 | REACTOME_PURINE_CATABOLISM | Genes involved in Purine catabolism |
0.2 | 0.3 | REACTOME_CDC6_ASSOCIATION_WITH_THE_ORC_ORIGIN_COMPLEX | Genes involved in CDC6 association with the ORC:origin complex |
0.1 | 1.7 | REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1 | Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1 |
0.1 | 1.7 | REACTOME_UNWINDING_OF_DNA | Genes involved in Unwinding of DNA |
0.1 | 1.6 | REACTOME_PURINE_SALVAGE | Genes involved in Purine salvage |
0.1 | 1.1 | REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS | Genes involved in Bile salt and organic anion SLC transporters |
0.1 | 1.5 | REACTOME_HDL_MEDIATED_LIPID_TRANSPORT | Genes involved in HDL-mediated lipid transport |
0.1 | 1.2 | REACTOME_PLATELET_SENSITIZATION_BY_LDL | Genes involved in Platelet sensitization by LDL |
0.0 | 0.7 | REACTOME_IRAK1_RECRUITS_IKK_COMPLEX | Genes involved in IRAK1 recruits IKK complex |
0.0 | 0.6 | REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY | Genes involved in Adenylate cyclase activating pathway |
0.0 | 0.5 | REACTOME_PROCESSIVE_SYNTHESIS_ON_THE_LAGGING_STRAND | Genes involved in Processive synthesis on the lagging strand |
0.0 | 1.3 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
0.0 | 0.7 | REACTOME_REVERSIBLE_HYDRATION_OF_CARBON_DIOXIDE | Genes involved in Reversible Hydration of Carbon Dioxide |
0.0 | 0.5 | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
0.0 | 0.7 | REACTOME_ACTIVATION_OF_THE_PRE_REPLICATIVE_COMPLEX | Genes involved in Activation of the pre-replicative complex |
0.0 | 0.9 | REACTOME_SULFUR_AMINO_ACID_METABOLISM | Genes involved in Sulfur amino acid metabolism |
0.0 | 0.4 | REACTOME_OPSINS | Genes involved in Opsins |
0.0 | 0.4 | REACTOME_ANDROGEN_BIOSYNTHESIS | Genes involved in Androgen biosynthesis |
0.0 | 0.6 | REACTOME_N_GLYCAN_ANTENNAE_ELONGATION | Genes involved in N-Glycan antennae elongation |
0.0 | 0.8 | REACTOME_SHC1_EVENTS_IN_ERBB4_SIGNALING | Genes involved in SHC1 events in ERBB4 signaling |
0.0 | 0.1 | REACTOME_RECYCLING_PATHWAY_OF_L1 | Genes involved in Recycling pathway of L1 |
0.0 | 0.1 | REACTOME_ADENYLATE_CYCLASE_INHIBITORY_PATHWAY | Genes involved in Adenylate cyclase inhibitory pathway |
0.0 | 2.2 | REACTOME_MITOTIC_PROMETAPHASE | Genes involved in Mitotic Prometaphase |
0.0 | 0.8 | REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION | Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression |
0.0 | 0.6 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
0.0 | 0.5 | REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION | Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) |
0.0 | 0.5 | REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY | Genes involved in Post-chaperonin tubulin folding pathway |
0.0 | 0.3 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.0 | 0.4 | REACTOME_FACILITATIVE_NA_INDEPENDENT_GLUCOSE_TRANSPORTERS | Genes involved in Facilitative Na+-independent glucose transporters |
0.0 | 0.5 | REACTOME_MICRORNA_MIRNA_BIOGENESIS | Genes involved in MicroRNA (miRNA) Biogenesis |
0.0 | 0.1 | REACTOME_REGULATORY_RNA_PATHWAYS | Genes involved in Regulatory RNA pathways |
0.0 | 0.4 | REACTOME_METABOLISM_OF_POLYAMINES | Genes involved in Metabolism of polyamines |
0.0 | 0.3 | REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION | Genes involved in Mitochondrial Fatty Acid Beta-Oxidation |
0.0 | 0.4 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.0 | 0.3 | REACTOME_VEGF_LIGAND_RECEPTOR_INTERACTIONS | Genes involved in VEGF ligand-receptor interactions |
0.0 | 0.6 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.0 | 0.1 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
0.0 | 0.4 | REACTOME_FATTY_ACYL_COA_BIOSYNTHESIS | Genes involved in Fatty Acyl-CoA Biosynthesis |
0.0 | 0.2 | REACTOME_SYNTHESIS_SECRETION_AND_DEACYLATION_OF_GHRELIN | Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin |
0.0 | 0.3 | REACTOME_RIP_MEDIATED_NFKB_ACTIVATION_VIA_DAI | Genes involved in RIP-mediated NFkB activation via DAI |
0.0 | 0.3 | REACTOME_ADP_SIGNALLING_THROUGH_P2RY12 | Genes involved in ADP signalling through P2Y purinoceptor 12 |
0.0 | 0.2 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
0.0 | 0.6 | REACTOME_MYOGENESIS | Genes involved in Myogenesis |
0.0 | 0.4 | REACTOME_ASSOCIATION_OF_TRIC_CCT_WITH_TARGET_PROTEINS_DURING_BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
0.0 | 0.4 | REACTOME_GROWTH_HORMONE_RECEPTOR_SIGNALING | Genes involved in Growth hormone receptor signaling |
0.0 | 0.0 | REACTOME_G1_S_SPECIFIC_TRANSCRIPTION | Genes involved in G1/S-Specific Transcription |
0.0 | 0.5 | REACTOME_MRNA_3_END_PROCESSING | Genes involved in mRNA 3'-end processing |
0.0 | 1.0 | REACTOME_LATE_PHASE_OF_HIV_LIFE_CYCLE | Genes involved in Late Phase of HIV Life Cycle |