Motif ID: HESX1

Z-value: 0.825


Transcription factors associated with HESX1:

Gene SymbolEntrez IDGene Name
HESX1 ENSG00000163666.4 HESX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HESX1hg19_v2_chr3_-_57233966_57234014-0.592.2e-03Click!


Activity profile for motif HESX1.

activity profile for motif HESX1


Sorted Z-values histogram for motif HESX1

Sorted Z-values for motif HESX1



Network of associatons between targets according to the STRING database.



First level regulatory network of HESX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_161337662 4.328 ENST00000367974.1
C1orf192
chromosome 1 open reading frame 192
chr11_+_101918153 3.313 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70


chromosome 11 open reading frame 70


chr6_+_52285131 3.231 ENST00000433625.2
EFHC1
EF-hand domain (C-terminal) containing 1
chr6_+_116937636 2.672 ENST00000368581.4
ENST00000229554.5
ENST00000368580.4
RSPH4A


radial spoke head 4 homolog A (Chlamydomonas)


chr1_-_42921915 2.616 ENST00000372565.3
ENST00000433602.2
ZMYND12

zinc finger, MYND-type containing 12

chr16_+_19421803 2.408 ENST00000541464.1
TMC5
transmembrane channel-like 5
chr6_+_52285046 2.251 ENST00000371068.5
EFHC1
EF-hand domain (C-terminal) containing 1
chr8_-_110656995 2.011 ENST00000276646.9
ENST00000533065.1
SYBU

syntabulin (syntaxin-interacting)

chr11_+_71791359 2.000 ENST00000419228.1
ENST00000435085.1
ENST00000307198.7
ENST00000538413.1
LRTOMT



leucine rich transmembrane and O-methyltransferase domain containing



chr16_+_4784273 1.933 ENST00000299320.5
ENST00000586724.1
C16orf71

chromosome 16 open reading frame 71

chr8_+_120885949 1.738 ENST00000523492.1
ENST00000286234.5
DEPTOR

DEP domain containing MTOR-interacting protein

chr1_+_15256230 1.684 ENST00000376028.4
ENST00000400798.2
KAZN

kazrin, periplakin interacting protein

chr2_-_160654745 1.659 ENST00000259053.4
ENST00000429078.2
CD302

CD302 molecule

chr11_-_5276008 1.342 ENST00000336906.4
HBG2
hemoglobin, gamma G
chr21_+_33784670 1.310 ENST00000300255.2
EVA1C
eva-1 homolog C (C. elegans)
chr2_+_230787213 1.308 ENST00000409992.1
FBXO36
F-box protein 36
chr5_+_149340282 1.282 ENST00000286298.4
SLC26A2
solute carrier family 26 (anion exchanger), member 2
chr1_+_3614591 1.275 ENST00000378290.4
TP73
tumor protein p73
chr2_+_230787201 1.270 ENST00000283946.3
FBXO36
F-box protein 36
chr2_+_85981008 1.262 ENST00000306279.3
ATOH8
atonal homolog 8 (Drosophila)
chr16_-_84273304 1.239 ENST00000308251.4
ENST00000568181.1
KCNG4

potassium voltage-gated channel, subfamily G, member 4

chr15_-_89089860 1.156 ENST00000558413.1
ENST00000564406.1
ENST00000268148.8
DET1


de-etiolated homolog 1 (Arabidopsis)


chr20_-_40247133 1.128 ENST00000373233.3
ENST00000309279.7
CHD6

chromodomain helicase DNA binding protein 6

chr7_-_95025661 1.111 ENST00000542556.1
ENST00000265627.5
ENST00000427422.1
ENST00000451904.1
PON1
PON3


paraoxonase 1
paraoxonase 3


chr6_+_116421976 1.052 ENST00000319550.4
ENST00000419791.1
NT5DC1

5'-nucleotidase domain containing 1

chr2_+_186603355 1.038 ENST00000343098.5
FSIP2
fibrous sheath interacting protein 2
chr2_-_43823093 0.991 ENST00000405006.4
THADA
thyroid adenoma associated
chr16_-_1661988 0.987 ENST00000426508.2
IFT140
intraflagellar transport 140 homolog (Chlamydomonas)
chr16_+_4784458 0.964 ENST00000590191.1
C16orf71
chromosome 16 open reading frame 71
chr9_+_1051481 0.948 ENST00000358146.2
ENST00000259622.6
DMRT2

doublesex and mab-3 related transcription factor 2

chr19_+_45312347 0.925 ENST00000270233.6
ENST00000591520.1
BCAM

basal cell adhesion molecule (Lutheran blood group)

chr9_-_123239632 0.902 ENST00000416449.1
CDK5RAP2
CDK5 regulatory subunit associated protein 2
chr19_+_11457232 0.887 ENST00000587531.1
CCDC159
coiled-coil domain containing 159
chr12_-_121019165 0.862 ENST00000341039.2
ENST00000357500.4
POP5

processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)

chr12_-_49582593 0.844 ENST00000295766.5
TUBA1A
tubulin, alpha 1a
chr19_-_45579762 0.839 ENST00000303809.2
ZNF296
zinc finger protein 296
chr17_-_57184260 0.822 ENST00000376149.3
ENST00000393066.3
TRIM37

tripartite motif containing 37

chr8_-_97273807 0.789 ENST00000517720.1
ENST00000287025.3
ENST00000523821.1
MTERFD1


MTERF domain containing 1


chr12_+_131438443 0.757 ENST00000261654.5
GPR133
G protein-coupled receptor 133
chr4_+_6784401 0.745 ENST00000425103.1
ENST00000307659.5
KIAA0232

KIAA0232

chr21_-_34852304 0.745 ENST00000542230.2
TMEM50B
transmembrane protein 50B
chr7_-_99679324 0.741 ENST00000292393.5
ENST00000413658.2
ENST00000412947.1
ENST00000441298.1
ENST00000449785.1
ENST00000299667.4
ENST00000424697.1
ZNF3






zinc finger protein 3






chr1_-_169337176 0.740 ENST00000472647.1
ENST00000367811.3
NME7

NME/NM23 family member 7

chr20_-_34117447 0.739 ENST00000246199.2
ENST00000424444.1
ENST00000374345.4
ENST00000444723.1
C20orf173



chromosome 20 open reading frame 173



chr1_+_156338993 0.732 ENST00000368249.1
ENST00000368246.2
ENST00000537040.1
ENST00000400992.2
ENST00000255013.3
ENST00000451864.2
RHBG





Rh family, B glycoprotein (gene/pseudogene)





chr6_-_41888814 0.650 ENST00000409060.1
ENST00000265350.4
MED20

mediator complex subunit 20

chr9_+_37079888 0.638 ENST00000429493.1
ENST00000593237.1
ENST00000588557.1
ENST00000430809.1
ENST00000592157.1
RP11-220I1.1




RP11-220I1.1




chr3_+_195943369 0.630 ENST00000296327.5
SLC51A
solute carrier family 51, alpha subunit
chr5_-_122758994 0.622 ENST00000306467.5
ENST00000515110.1
CEP120

centrosomal protein 120kDa

chr12_-_55367361 0.613 ENST00000532804.1
ENST00000531122.1
ENST00000533446.1
TESPA1


thymocyte expressed, positive selection associated 1


chr7_+_74508372 0.610 ENST00000356115.5
ENST00000430511.2
ENST00000312575.7
GTF2IRD2B


GTF2I repeat domain containing 2B


chr14_-_70883708 0.572 ENST00000256366.4
SYNJ2BP
synaptojanin 2 binding protein
chr2_-_43823119 0.551 ENST00000403856.1
ENST00000404790.1
ENST00000405975.2
ENST00000415080.2
THADA



thyroid adenoma associated



chr13_-_52378231 0.549 ENST00000280056.2
ENST00000444610.2
DHRS12

dehydrogenase/reductase (SDR family) member 12

chr11_+_73019282 0.534 ENST00000263674.3
ARHGEF17
Rho guanine nucleotide exchange factor (GEF) 17
chr2_+_233562015 0.520 ENST00000427233.1
ENST00000373566.3
ENST00000373563.4
ENST00000428883.1
ENST00000456491.1
ENST00000409480.1
ENST00000421433.1
ENST00000425040.1
ENST00000430720.1
ENST00000409547.1
ENST00000423659.1
ENST00000409196.3
ENST00000409451.3
ENST00000429187.1
ENST00000440945.1
GIGYF2














GRB10 interacting GYF protein 2














chr4_-_2264015 0.508 ENST00000337190.2
MXD4
MAX dimerization protein 4
chr1_-_109968973 0.506 ENST00000271308.4
ENST00000538610.1
PSMA5

proteasome (prosome, macropain) subunit, alpha type, 5

chr3_-_196695692 0.505 ENST00000412723.1
PIGZ
phosphatidylinositol glycan anchor biosynthesis, class Z
chr3_-_51975942 0.502 ENST00000232888.6
RRP9
ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)
chr11_-_1629693 0.499 ENST00000399685.1
KRTAP5-3
keratin associated protein 5-3
chr17_+_55163075 0.499 ENST00000571629.1
ENST00000570423.1
ENST00000575186.1
ENST00000573085.1
ENST00000572814.1
AKAP1




A kinase (PRKA) anchor protein 1




chr16_-_70719925 0.477 ENST00000338779.6
MTSS1L
metastasis suppressor 1-like
chr22_+_18632666 0.473 ENST00000215794.7
USP18
ubiquitin specific peptidase 18
chr6_-_83775489 0.470 ENST00000369747.3
UBE3D
ubiquitin protein ligase E3D
chr6_-_167275991 0.448 ENST00000510118.1
RPS6KA2
ribosomal protein S6 kinase, 90kDa, polypeptide 2
chr17_+_36861735 0.440 ENST00000378137.5
ENST00000325718.7
MLLT6

myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6

chrX_-_7895479 0.438 ENST00000381042.4
PNPLA4
patatin-like phospholipase domain containing 4
chr10_+_103348031 0.434 ENST00000370151.4
ENST00000370147.1
ENST00000370148.2
DPCD


deleted in primary ciliary dyskinesia homolog (mouse)


chr4_-_89619386 0.425 ENST00000323061.5
NAP1L5
nucleosome assembly protein 1-like 5
chr10_+_90672113 0.420 ENST00000371922.1
STAMBPL1
STAM binding protein-like 1
chr16_+_66914264 0.418 ENST00000311765.2
ENST00000568869.1
ENST00000561704.1
ENST00000568398.1
ENST00000566776.1
PDP2




pyruvate dehyrogenase phosphatase catalytic subunit 2




chr5_-_122759032 0.415 ENST00000510582.3
ENST00000328236.5
ENST00000306481.6
ENST00000508442.2
ENST00000395431.2
CEP120




centrosomal protein 120kDa




chrX_+_37850026 0.411 ENST00000341016.3
CXorf27
chromosome X open reading frame 27
chr7_-_37024665 0.395 ENST00000396040.2
ELMO1
engulfment and cell motility 1
chr9_-_34376851 0.386 ENST00000297625.7
KIAA1161
KIAA1161
chr4_+_129349188 0.379 ENST00000511497.1
RP11-420A23.1
RP11-420A23.1
chr7_-_74267836 0.375 ENST00000361071.5
ENST00000453619.2
ENST00000417115.2
ENST00000405086.2
GTF2IRD2



GTF2I repeat domain containing 2



chr13_+_100741269 0.370 ENST00000376286.4
ENST00000376279.3
ENST00000376285.1
PCCA


propionyl CoA carboxylase, alpha polypeptide


chr17_-_57184064 0.367 ENST00000262294.7
TRIM37
tripartite motif containing 37
chr11_+_126139005 0.359 ENST00000263578.5
ENST00000442061.2
ENST00000532125.1
FOXRED1


FAD-dependent oxidoreductase domain containing 1


chr19_+_38397839 0.357 ENST00000222345.6
SIPA1L3
signal-induced proliferation-associated 1 like 3
chr6_-_41888843 0.356 ENST00000434077.1
ENST00000409312.1
MED20

mediator complex subunit 20

chr11_-_4414880 0.355 ENST00000254436.7
ENST00000543625.1
TRIM21

tripartite motif containing 21

chr3_+_192958914 0.352 ENST00000264735.2
ENST00000602513.1
HRASLS

HRAS-like suppressor

chr16_-_57219966 0.328 ENST00000565760.1
ENST00000309137.8
ENST00000570184.1
ENST00000562324.1
FAM192A



family with sequence similarity 192, member A



chr3_-_131753830 0.323 ENST00000429747.1
CPNE4
copine IV
chr2_+_220071490 0.322 ENST00000409206.1
ENST00000409594.1
ENST00000289528.5
ENST00000422255.1
ENST00000409412.1
ENST00000409097.1
ENST00000409336.1
ENST00000409217.1
ENST00000409319.1
ENST00000444522.2
ZFAND2B









zinc finger, AN1-type domain 2B









chr19_-_39694894 0.315 ENST00000318438.6
SYCN
syncollin
chr13_+_108870714 0.309 ENST00000375898.3
ABHD13
abhydrolase domain containing 13
chr19_+_46498704 0.308 ENST00000595358.1
ENST00000594672.1
ENST00000536603.1
CCDC61


coiled-coil domain containing 61


chr14_-_25103388 0.303 ENST00000526004.1
ENST00000415355.3
GZMB

granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)

chr14_-_90798273 0.301 ENST00000357904.3
NRDE2
NRDE-2, necessary for RNA interference, domain containing
chr11_+_67222818 0.291 ENST00000325656.5
CABP4
calcium binding protein 4
chr8_+_124084899 0.289 ENST00000287380.1
ENST00000309336.3
ENST00000519418.1
ENST00000327098.5
ENST00000522420.1
ENST00000521676.1
ENST00000378080.2
TBC1D31






TBC1 domain family, member 31






chr12_-_123717643 0.288 ENST00000541437.1
ENST00000606320.1
MPHOSPH9

M-phase phosphoprotein 9

chr4_+_175204818 0.281 ENST00000503780.1
CEP44
centrosomal protein 44kDa
chr1_-_20446020 0.269 ENST00000375105.3
PLA2G2D
phospholipase A2, group IID
chr16_-_57219926 0.268 ENST00000566584.1
ENST00000566481.1
ENST00000566077.1
ENST00000564108.1
ENST00000565458.1
ENST00000566681.1
ENST00000567439.1
FAM192A






family with sequence similarity 192, member A






chr2_-_89513402 0.261 ENST00000498435.1
IGKV1-27
immunoglobulin kappa variable 1-27
chr21_+_38445539 0.259 ENST00000418766.1
ENST00000450533.1
ENST00000438055.1
ENST00000355666.1
ENST00000540756.1
ENST00000399010.1
TTC3





tetratricopeptide repeat domain 3





chr5_-_176057518 0.258 ENST00000393693.2
SNCB
synuclein, beta
chr10_+_26505594 0.254 ENST00000259271.3
GAD2
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa)
chr1_+_152658599 0.254 ENST00000368780.3
LCE2B
late cornified envelope 2B
chr8_-_145060593 0.247 ENST00000313059.5
ENST00000524918.1
ENST00000313028.7
ENST00000525773.1
PARP10



poly (ADP-ribose) polymerase family, member 10



chr21_+_34398153 0.241 ENST00000382357.3
ENST00000430860.1
ENST00000333337.3
OLIG2


oligodendrocyte lineage transcription factor 2


chr17_+_18128896 0.237 ENST00000316843.4
LLGL1
lethal giant larvae homolog 1 (Drosophila)
chr16_+_1662326 0.234 ENST00000397412.3
CRAMP1L
Crm, cramped-like (Drosophila)
chr2_-_89340242 0.233 ENST00000480492.1
IGKV1-12
immunoglobulin kappa variable 1-12
chr2_-_89399845 0.233 ENST00000479981.1
IGKV1-16
immunoglobulin kappa variable 1-16
chr21_+_46020497 0.229 ENST00000380102.2
KRTAP10-7
keratin associated protein 10-7
chr14_-_25103472 0.227 ENST00000216341.4
ENST00000382542.1
ENST00000382540.1
GZMB


granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1)


chr16_-_57219721 0.226 ENST00000562406.1
ENST00000568671.1
ENST00000567044.1
FAM192A


family with sequence similarity 192, member A


chr18_+_54318566 0.222 ENST00000589935.1
ENST00000357574.3
WDR7

WD repeat domain 7

chr5_+_78532003 0.217 ENST00000396137.4
JMY
junction mediating and regulatory protein, p53 cofactor
chr15_-_83316711 0.215 ENST00000568128.1
CPEB1
cytoplasmic polyadenylation element binding protein 1
chr11_-_126138808 0.209 ENST00000332118.6
ENST00000532259.1
SRPR

signal recognition particle receptor (docking protein)

chr17_+_46018872 0.208 ENST00000583599.1
ENST00000434554.2
ENST00000225573.4
ENST00000544840.1
ENST00000534893.1
PNPO




pyridoxamine 5'-phosphate oxidase




chr8_+_146277764 0.202 ENST00000331434.6
C8orf33
chromosome 8 open reading frame 33
chrX_-_64754611 0.193 ENST00000374807.5
ENST00000374811.3
ENST00000374804.5
ENST00000312391.8
LAS1L



LAS1-like (S. cerevisiae)



chr6_+_56820018 0.187 ENST00000370746.3
BEND6
BEN domain containing 6
chr19_+_19431490 0.179 ENST00000392313.6
ENST00000262815.8
ENST00000609122.1
MAU2


MAU2 sister chromatid cohesion factor


chr2_-_96931679 0.178 ENST00000258439.3
ENST00000432959.1
TMEM127

transmembrane protein 127

chr3_+_138153451 0.169 ENST00000389567.4
ENST00000289135.4
ESYT3

extended synaptotagmin-like protein 3

chr3_+_178253993 0.165 ENST00000420517.2
ENST00000452583.1
KCNMB2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

chr19_+_41699135 0.161 ENST00000542619.1
ENST00000600561.1
CYP2S1

cytochrome P450, family 2, subfamily S, polypeptide 1

chr3_+_155860751 0.160 ENST00000471742.1
KCNAB1
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chrX_+_135730373 0.159 ENST00000370628.2
CD40LG
CD40 ligand
chr7_+_1022811 0.158 ENST00000308919.7
CYP2W1
cytochrome P450, family 2, subfamily W, polypeptide 1
chr8_+_109455845 0.157 ENST00000220853.3
EMC2
ER membrane protein complex subunit 2
chr2_+_32502952 0.157 ENST00000238831.4
YIPF4
Yip1 domain family, member 4
chr11_+_47586982 0.156 ENST00000426530.2
ENST00000534775.1
PTPMT1

protein tyrosine phosphatase, mitochondrial 1

chr2_-_128051670 0.156 ENST00000493187.2
ERCC3
excision repair cross-complementing rodent repair deficiency, complementation group 3
chr13_-_108870623 0.155 ENST00000405925.1
LIG4
ligase IV, DNA, ATP-dependent
chr20_+_47835884 0.152 ENST00000371764.4
DDX27
DEAD (Asp-Glu-Ala-Asp) box polypeptide 27
chr1_-_1356628 0.149 ENST00000442470.1
ENST00000537107.1
ANKRD65

ankyrin repeat domain 65

chrX_+_135730297 0.146 ENST00000370629.2
CD40LG
CD40 ligand
chr6_+_56819773 0.145 ENST00000370750.2
BEND6
BEN domain containing 6
chr21_-_38445470 0.144 ENST00000399098.1
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr16_+_56995762 0.141 ENST00000200676.3
ENST00000379780.2
CETP

cholesteryl ester transfer protein, plasma

chr4_-_175204765 0.137 ENST00000513696.1
ENST00000503293.1
FBXO8

F-box protein 8

chr1_-_16302565 0.136 ENST00000537142.1
ENST00000448462.2
ZBTB17

zinc finger and BTB domain containing 17

chr12_+_13197218 0.129 ENST00000197268.8
KIAA1467
KIAA1467
chr1_-_165738072 0.129 ENST00000481278.1
TMCO1
transmembrane and coiled-coil domains 1
chr21_-_38445011 0.127 ENST00000464265.1
ENST00000399102.1
PIGP

phosphatidylinositol glycan anchor biosynthesis, class P

chr16_-_14724057 0.125 ENST00000539279.1
ENST00000420015.2
ENST00000437198.2
PARN


poly(A)-specific ribonuclease


chr10_+_121652204 0.125 ENST00000369075.3
ENST00000543134.1
SEC23IP

SEC23 interacting protein

chr1_-_54637997 0.125 ENST00000536061.1
AL357673.1
CDNA: FLJ21031 fis, clone CAE07336; HCG1780521; Uncharacterized protein
chr2_-_74875432 0.124 ENST00000536235.1
ENST00000421985.1
M1AP

meiosis 1 associated protein

chr8_+_71581565 0.121 ENST00000408926.3
ENST00000520030.1
XKR9

XK, Kell blood group complex subunit-related family, member 9

chr6_-_42981651 0.118 ENST00000244711.3
MEA1
male-enhanced antigen 1
chr12_-_53228079 0.116 ENST00000330553.5
KRT79
keratin 79
chr15_+_32322709 0.116 ENST00000455693.2
CHRNA7
cholinergic receptor, nicotinic, alpha 7 (neuronal)
chr20_-_5485166 0.115 ENST00000589201.1
ENST00000379053.4
LINC00654

long intergenic non-protein coding RNA 654

chr14_-_90798418 0.114 ENST00000354366.3
NRDE2
NRDE-2, necessary for RNA interference, domain containing
chr4_+_15683404 0.114 ENST00000422728.2
FAM200B
family with sequence similarity 200, member B
chr11_+_47587129 0.113 ENST00000326656.8
ENST00000326674.9
PTPMT1

protein tyrosine phosphatase, mitochondrial 1

chr7_+_23637118 0.107 ENST00000448353.1
CCDC126
coiled-coil domain containing 126
chr4_+_15683369 0.105 ENST00000503617.1
FAM200B
family with sequence similarity 200, member B
chr2_+_90192768 0.105 ENST00000390275.2
IGKV1D-13
immunoglobulin kappa variable 1D-13
chrX_+_118602363 0.103 ENST00000317881.8
SLC25A5
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
chr2_-_197036289 0.102 ENST00000263955.4
STK17B
serine/threonine kinase 17b
chr8_-_101734308 0.099 ENST00000519004.1
ENST00000519363.1
ENST00000520142.1
PABPC1


poly(A) binding protein, cytoplasmic 1


chrX_+_153409678 0.091 ENST00000369951.4
OPN1LW
opsin 1 (cone pigments), long-wave-sensitive
chr2_+_128175997 0.086 ENST00000234071.3
ENST00000429925.1
ENST00000442644.1
ENST00000453608.2
PROC



protein C (inactivator of coagulation factors Va and VIIIa)



chr2_+_234216454 0.085 ENST00000447536.1
ENST00000409110.1
SAG

S-antigen; retina and pineal gland (arrestin)

chr1_+_46016703 0.085 ENST00000481885.1
ENST00000351829.4
ENST00000471651.1
AKR1A1


aldo-keto reductase family 1, member A1 (aldehyde reductase)


chr12_-_54070098 0.077 ENST00000394349.3
ENST00000549164.1
ATP5G2

ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C2 (subunit 9)

chr12_-_121476750 0.075 ENST00000543677.1
OASL
2'-5'-oligoadenylate synthetase-like
chr14_+_45553296 0.075 ENST00000355765.6
ENST00000553605.1
PRPF39

pre-mRNA processing factor 39

chr18_+_56892724 0.069 ENST00000456142.3
ENST00000530323.1
GRP

gastrin-releasing peptide

chr7_+_1022973 0.068 ENST00000340150.6
CYP2W1
cytochrome P450, family 2, subfamily W, polypeptide 1
chr1_+_47799446 0.068 ENST00000371873.5
CMPK1
cytidine monophosphate (UMP-CMP) kinase 1, cytosolic
chr8_-_101734170 0.067 ENST00000522387.1
ENST00000518196.1
PABPC1

poly(A) binding protein, cytoplasmic 1

chr4_-_48782259 0.062 ENST00000507711.1
ENST00000358350.4
ENST00000537810.1
ENST00000264319.7
FRYL



FRY-like



chr1_-_165738085 0.061 ENST00000464650.1
ENST00000392129.6
TMCO1

transmembrane and coiled-coil domains 1

chr17_-_15168624 0.059 ENST00000312280.3
ENST00000494511.1
ENST00000580584.1
PMP22


peripheral myelin protein 22


chr18_-_44702668 0.049 ENST00000256433.3
IER3IP1
immediate early response 3 interacting protein 1
chr11_+_125774258 0.045 ENST00000263576.6
DDX25
DEAD (Asp-Glu-Ala-Asp) box helicase 25
chr6_-_110797799 0.045 ENST00000456137.2
ENST00000368919.3
ENST00000439654.1
SLC22A16


solute carrier family 22 (organic cation/carnitine transporter), member 16


chr7_+_99746514 0.041 ENST00000341942.5
ENST00000441173.1
LAMTOR4

late endosomal/lysosomal adaptor, MAPK and MTOR activator 4

chr18_-_70535177 0.040 ENST00000327305.6
NETO1
neuropilin (NRP) and tolloid (TLL)-like 1
chr21_-_38445443 0.038 ENST00000360525.4
PIGP
phosphatidylinositol glycan anchor biosynthesis, class P
chr6_+_109416684 0.035 ENST00000521522.1
ENST00000524064.1
ENST00000522608.1
ENST00000521503.1
ENST00000519407.1
ENST00000519095.1
ENST00000368968.2
ENST00000522490.1
ENST00000523209.1
ENST00000368970.2
ENST00000520883.1
ENST00000523787.1
CEP57L1











centrosomal protein 57kDa-like 1











chr2_+_90198535 0.032 ENST00000390276.2
IGKV1D-12
immunoglobulin kappa variable 1D-12
chr15_+_22892663 0.027 ENST00000313077.7
ENST00000561274.1
ENST00000560848.1
CYFIP1


cytoplasmic FMR1 interacting protein 1


chr22_+_31892373 0.025 ENST00000443011.1
ENST00000400289.1
ENST00000444859.1
ENST00000400288.2
SFI1



Sfi1 homolog, spindle assembly associated (yeast)



chr9_+_21440440 0.025 ENST00000276927.1
IFNA1
interferon, alpha 1
chr20_+_35807512 0.023 ENST00000373622.5
RPN2
ribophorin II
chr3_+_158519654 0.019 ENST00000415822.2
ENST00000392813.4
ENST00000264266.8
MFSD1


major facilitator superfamily domain containing 1


chr19_+_34919257 0.018 ENST00000246548.4
ENST00000590048.2
UBA2

ubiquitin-like modifier activating enzyme 2

chr11_+_118443098 0.013 ENST00000392859.3
ENST00000359415.4
ENST00000534182.2
ENST00000264028.4
ARCN1



archain 1



chr15_-_51058005 0.004 ENST00000261854.5
SPPL2A
signal peptide peptidase like 2A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.4 1.5 GO:1901895 negative regulation of calcium-transporting ATPase activity(GO:1901895)
0.3 1.1 GO:0034445 regulation of plasma lipoprotein particle oxidation(GO:0034444) negative regulation of plasma lipoprotein particle oxidation(GO:0034445) phenylpropanoid catabolic process(GO:0046271)
0.2 0.7 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.2 1.3 GO:0050428 purine ribonucleoside bisphosphate biosynthetic process(GO:0034036) 3'-phosphoadenosine 5'-phosphosulfate biosynthetic process(GO:0050428)
0.2 0.9 GO:0061055 myotome development(GO:0061055)
0.2 0.6 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 1.0 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.1 1.1 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.2 GO:0043385 mycotoxin metabolic process(GO:0043385) aflatoxin metabolic process(GO:0046222) organic heteropentacyclic compound metabolic process(GO:1901376)
0.1 2.0 GO:0019614 catechol-containing compound catabolic process(GO:0019614) catecholamine catabolic process(GO:0042424)
0.1 1.7 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 1.0 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.1 0.4 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 0.9 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.9 GO:0046600 negative regulation of centriole replication(GO:0046600)
0.1 0.2 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)
0.1 0.5 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.1 5.5 GO:0021795 cerebral cortex cell migration(GO:0021795)
0.1 1.3 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 0.2 GO:0010847 regulation of chromatin assembly(GO:0010847) negative regulation of protein import into nucleus, translocation(GO:0033159) protein auto-ADP-ribosylation(GO:0070213)
0.1 0.4 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 1.3 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.1 0.6 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.1 0.7 GO:0006228 UTP biosynthetic process(GO:0006228)
0.1 1.1 GO:0015671 oxygen transport(GO:0015671)
0.1 0.4 GO:0021678 third ventricle development(GO:0021678)
0.1 0.3 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.2 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.1 0.2 GO:0051102 DNA ligation involved in DNA recombination(GO:0051102)
0.0 0.3 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
0.0 0.3 GO:0006616 SRP-dependent cotranslational protein targeting to membrane, translocation(GO:0006616)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 2.7 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.3 GO:0006540 glutamate decarboxylation to succinate(GO:0006540)
0.0 0.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.7 GO:0097503 sialylation(GO:0097503)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.2 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.9 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 0.1 GO:0050893 sensory processing(GO:0050893)
0.0 0.8 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.0 1.8 GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061178)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343) positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0015853 adenine transport(GO:0015853)
0.0 0.4 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.4 GO:0016246 RNA interference(GO:0016246)
0.0 0.5 GO:0021522 spinal cord motor neuron differentiation(GO:0021522)
0.0 0.6 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0000478 endonucleolytic cleavage involved in rRNA processing(GO:0000478)
0.0 1.8 GO:0070268 cornification(GO:0070268)
0.0 0.3 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.5 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0001534 radial spoke(GO:0001534)
0.2 2.0 GO:0097433 dense body(GO:0097433)
0.2 1.5 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.9 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 1.0 GO:0030991 intraciliary transport particle A(GO:0030991)
0.1 0.7 GO:1990635 proximal dendrite(GO:1990635)
0.1 1.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 1.1 GO:0005833 hemoglobin complex(GO:0005833)
0.1 1.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 1.7 GO:0030057 desmosome(GO:0030057)
0.0 5.6 GO:0072686 mitotic spindle(GO:0072686)
0.0 0.4 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.5 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 1.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.1 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.7 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.2 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.3 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 1.0 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0061200 clathrin-sculpted gamma-aminobutyric acid transport vesicle(GO:0061200) clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane(GO:0061202)
0.0 1.7 GO:0005902 microvillus(GO:0005902)
0.0 0.2 GO:0000439 core TFIIH complex(GO:0000439)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.2 GO:0072546 ER membrane protein complex(GO:0072546)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0102007 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.2 2.0 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.2 0.5 GO:0000026 alpha-1,2-mannosyltransferase activity(GO:0000026)
0.1 0.7 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.1 1.3 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.3 GO:0005174 CD40 receptor binding(GO:0005174)
0.1 1.3 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 0.4 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 0.5 GO:0034511 U3 snoRNA binding(GO:0034511)
0.1 0.4 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 1.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 2.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 1.1 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0017129 triglyceride binding(GO:0017129)
0.0 0.4 GO:0004075 biotin carboxylase activity(GO:0004075) biotin binding(GO:0009374)
0.0 1.2 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.2 GO:0032564 adenyl deoxyribonucleotide binding(GO:0032558) dATP binding(GO:0032564)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.1 GO:0005471 ATP:ADP antiporter activity(GO:0005471) adenine transmembrane transporter activity(GO:0015207)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 1.2 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0030506 ankyrin binding(GO:0030506)
0.0 1.3 GO:0070888 E-box binding(GO:0070888)
0.0 1.3 GO:0001221 transcription cofactor binding(GO:0001221)
0.0 6.3 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.3 GO:1903136 cuprous ion binding(GO:1903136)
0.0 0.3 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 1.0 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.5 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.2 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.9 GO:0001012 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) RNA polymerase II regulatory region DNA binding(GO:0001012)
0.0 0.2 GO:0010181 FMN binding(GO:0010181)
0.0 0.2 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.0 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.5 GO:0030332 cyclin binding(GO:0030332)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA_CASPASE_CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 ST_ERK1_ERK2_MAPK_PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.3 PID_ATF2_PATHWAY ATF-2 transcription factor network
0.0 1.4 PID_MTOR_4PATHWAY mTOR signaling pathway
0.0 0.9 ST_DIFFERENTIATION_PATHWAY_IN_PC12_CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.3 PID_CD40_PATHWAY CD40/CD40L signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.4 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.4 REACTOME_VOLTAGE_GATED_POTASSIUM_CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME_MITOCHONDRIAL_FATTY_ACID_BETA_OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME_ACYL_CHAIN_REMODELLING_OF_PS Genes involved in Acyl chain remodelling of PS
0.0 0.5 REACTOME_REGULATION_OF_IFNA_SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.4 REACTOME_ERK_MAPK_TARGETS Genes involved in ERK/MAPK targets
0.0 0.3 REACTOME_SYNTHESIS_OF_GLYCOSYLPHOSPHATIDYLINOSITOL_GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)