Motif ID: HINFP1

Z-value: 0.477





Activity profile for motif HINFP1.

activity profile for motif HINFP1


Sorted Z-values histogram for motif HINFP1

Sorted Z-values for motif HINFP1



Network of associatons between targets according to the STRING database.



First level regulatory network of HINFP1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_154393260 1.624 ENST00000435029.4
 KIF4B
kinesin family member 4B
chr2_-_234763147 1.191 ENST00000411486.2
ENST00000432087.1
ENST00000441687.1
ENST00000414924.1
 HJURP



Holliday junction recognition protein



chr9_-_94186131 0.985 ENST00000297689.3
 NFIL3
nuclear factor, interleukin 3 regulated
chr18_+_12308046 0.985 ENST00000317702.5
 TUBB6
tubulin, beta 6 class V
chr18_+_12308231 0.879 ENST00000590103.1
ENST00000591909.1
ENST00000586653.1
ENST00000592683.1
ENST00000590967.1
ENST00000591208.1
ENST00000591463.1
 TUBB6






tubulin, beta 6 class V






chr14_+_55033815 0.846 ENST00000554335.1
 SAMD4A
sterile alpha motif domain containing 4A
chr1_-_94147385 0.726 ENST00000260502.6
 BCAR3
breast cancer anti-estrogen resistance 3
chr10_-_75634219 0.687 ENST00000305762.7
 CAMK2G
calcium/calmodulin-dependent protein kinase II gamma
chr16_+_57279248 0.641 ENST00000562023.1
ENST00000563234.1
 ARL2BP

ADP-ribosylation factor-like 2 binding protein

chr10_-_75634260 0.628 ENST00000372765.1
ENST00000351293.3
 CAMK2G

calcium/calmodulin-dependent protein kinase II gamma

chr11_-_61658853 0.538 ENST00000525588.1
ENST00000540820.1
 FADS3

fatty acid desaturase 3

chr20_+_35974532 0.533 ENST00000373578.2
 SRC
v-src avian sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
chr2_-_130939115 0.528 ENST00000441135.1
ENST00000339679.7
ENST00000426662.2
ENST00000443958.2
ENST00000351288.6
ENST00000453750.1
ENST00000452225.2
 SMPD4






sphingomyelin phosphodiesterase 4, neutral membrane (neutral sphingomyelinase-3)






chr11_-_61659006 0.514 ENST00000278829.2
 FADS3
fatty acid desaturase 3
chr16_+_610407 0.511 ENST00000409413.3
 C16orf11
chromosome 16 open reading frame 11
chr21_+_35445811 0.459 ENST00000399312.2
 MRPS6
mitochondrial ribosomal protein S6
chr10_-_75634326 0.456 ENST00000322635.3
ENST00000444854.2
ENST00000423381.1
ENST00000322680.3
ENST00000394762.2
 CAMK2G




calcium/calmodulin-dependent protein kinase II gamma




chr2_+_130939827 0.443 ENST00000409255.1
ENST00000455239.1
 MZT2B

mitotic spindle organizing protein 2B

chr2_+_130939235 0.439 ENST00000425361.1
ENST00000457492.1
 MZT2B

mitotic spindle organizing protein 2B

chr1_-_43232649 0.383 ENST00000372526.2
ENST00000236040.4
ENST00000296388.5
ENST00000397054.3
 LEPRE1



leucine proline-enriched proteoglycan (leprecan) 1



chr21_+_35445827 0.380 ENST00000381151.3
ENST00000608209.1
 SLC5A3
SLC5A3
solute carrier family 5 (sodium/myo-inositol cotransporter), member 3
sodium/myo-inositol cotransporter
chr3_+_133293278 0.357 ENST00000508481.1
ENST00000420115.2
ENST00000504867.1
ENST00000507408.1
ENST00000511392.1
ENST00000515421.1
 CDV3





CDV3 homolog (mouse)





chr3_+_133292851 0.352 ENST00000503932.1
 CDV3
CDV3 homolog (mouse)
chrX_-_119249819 0.338 ENST00000217999.2
 RHOXF1
Rhox homeobox family, member 1
chr22_+_27053422 0.334 ENST00000413665.1
ENST00000421151.1
ENST00000456129.1
ENST00000430080.1
 MIAT



myocardial infarction associated transcript (non-protein coding)



chr1_-_62784935 0.310 ENST00000354381.3
 KANK4
KN motif and ankyrin repeat domains 4
chr3_+_133292759 0.283 ENST00000431519.2
 CDV3
CDV3 homolog (mouse)
chr2_+_58655461 0.269 ENST00000429095.1
ENST00000429664.1
ENST00000452840.1
 AC007092.1


long intergenic non-protein coding RNA 1122


chrX_-_125686784 0.265 ENST00000371126.1
 DCAF12L1
DDB1 and CUL4 associated factor 12-like 1
chr13_-_22033392 0.254 ENST00000320220.9
ENST00000415724.1
ENST00000422251.1
ENST00000382466.3
ENST00000542645.1
ENST00000400590.3
 ZDHHC20





zinc finger, DHHC-type containing 20





chr10_+_72238517 0.229 ENST00000263563.6
 PALD1
phosphatase domain containing, paladin 1
chr1_+_222886694 0.207 ENST00000426638.1
ENST00000537020.1
ENST00000539697.1
 BROX


BRO1 domain and CAAX motif containing


chr10_-_977564 0.185 ENST00000406525.2
 LARP4B
La ribonucleoprotein domain family, member 4B
chr18_+_11981547 0.183 ENST00000588927.1
 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr15_+_85525205 0.174 ENST00000394553.1
ENST00000339708.5
 PDE8A

phosphodiesterase 8A

chr19_-_14228541 0.142 ENST00000590853.1
ENST00000308677.4
 PRKACA

protein kinase, cAMP-dependent, catalytic, alpha

chr17_-_79481666 0.135 ENST00000575659.1
 ACTG1
actin, gamma 1
chr19_-_5680499 0.131 ENST00000587589.1
 C19orf70
chromosome 19 open reading frame 70
chr6_-_144416737 0.110 ENST00000367569.2
 SF3B5
splicing factor 3b, subunit 5, 10kDa
chr18_+_11981427 0.102 ENST00000269159.3
 IMPA2
inositol(myo)-1(or 4)-monophosphatase 2
chr1_+_210111534 0.083 ENST00000422431.1
ENST00000534859.1
ENST00000399639.2
ENST00000537238.1
 SYT14



synaptotagmin XIV



chr14_+_73704201 0.069 ENST00000340738.5
ENST00000427855.1
ENST00000381166.3
 PAPLN


papilin, proteoglycan-like sulfated glycoprotein


chr10_-_97453650 0.054 ENST00000371209.5
ENST00000371217.5
ENST00000430368.2
 TCTN3


tectonic family member 3


chr1_+_42922173 0.031 ENST00000455780.1
ENST00000372560.3
ENST00000372561.3
ENST00000372556.3
 PPCS



phosphopantothenoylcysteine synthetase



chr1_-_62785054 0.022 ENST00000371153.4
 KANK4
KN motif and ankyrin repeat domains 4
chr2_-_96811170 0.018 ENST00000288943.4
 DUSP2
dual specificity phosphatase 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0071393 cellular response to progesterone stimulus(GO:0071393)
0.1 1.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.8 GO:1901897 regulation of relaxation of cardiac muscle(GO:1901897)
0.1 0.4 GO:0015798 myo-inositol transport(GO:0015798)
0.0 0.3 GO:0006021 inositol biosynthetic process(GO:0006021)
0.0 0.5 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 1.2 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.6 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 1.0 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.8 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 1.1 GO:0006636 unsaturated fatty acid biosynthetic process(GO:0006636)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 1.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.8 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:0097433 dense body(GO:0097433)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.1 0.3 GO:0052832 inositol monophosphate 1-phosphatase activity(GO:0008934) inositol monophosphate 3-phosphatase activity(GO:0052832) inositol monophosphate 4-phosphatase activity(GO:0052833) inositol monophosphate phosphatase activity(GO:0052834)
0.1 0.5 GO:0071253 connexin binding(GO:0071253)
0.0 1.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.5 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.4 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.8 GO:0030371 translation repressor activity(GO:0030371)
0.0 2.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 ST_WNT_CA2_CYCLIC_GMP_PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 ST_STAT3_PATHWAY STAT3 Pathway
0.0 0.7 PID_CDC42_REG_PATHWAY Regulation of CDC42 activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME_POST_CHAPERONIN_TUBULIN_FOLDING_PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.2 REACTOME_RECYCLING_PATHWAY_OF_L1 Genes involved in Recycling pathway of L1
0.0 1.2 REACTOME_DEPOSITION_OF_NEW_CENPA_CONTAINING_NUCLEOSOMES_AT_THE_CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere