Motif ID: HMBOX1

Z-value: 0.786


Transcription factors associated with HMBOX1:

Gene SymbolEntrez IDGene Name
HMBOX1 ENSG00000147421.13 HMBOX1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HMBOX1hg19_v2_chr8_+_28747884_287479380.692.2e-04Click!


Activity profile for motif HMBOX1.

activity profile for motif HMBOX1


Sorted Z-values histogram for motif HMBOX1

Sorted Z-values for motif HMBOX1



Network of associatons between targets according to the STRING database.



First level regulatory network of HMBOX1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_25348007 3.102 ENST00000354189.5
ENST00000545133.1
ENST00000554347.1
ENST00000395987.3
ENST00000320267.9
ENST00000395990.2
ENST00000537577.1
CASC1






cancer susceptibility candidate 1






chr6_+_88117683 2.743 ENST00000369562.4
C6ORF165
UPF0704 protein C6orf165
chr6_+_112408768 2.477 ENST00000368656.2
ENST00000604268.1
FAM229B

family with sequence similarity 229, member B

chr9_-_117111222 1.865 ENST00000374079.4
AKNA
AT-hook transcription factor
chr4_+_9172135 1.796 ENST00000512047.1
FAM90A26
family with sequence similarity 90, member A26
chr6_-_52668605 1.782 ENST00000334575.5
GSTA1
glutathione S-transferase alpha 1
chr13_+_24144509 1.570 ENST00000248484.4
TNFRSF19
tumor necrosis factor receptor superfamily, member 19
chr14_+_75536335 1.516 ENST00000554763.1
ENST00000439583.2
ENST00000526130.1
ENST00000525046.1
ZC2HC1C



zinc finger, C2HC-type containing 1C



chr14_+_75536280 1.482 ENST00000238686.8
ZC2HC1C
zinc finger, C2HC-type containing 1C
chr3_-_57530051 1.383 ENST00000311202.6
ENST00000351747.2
ENST00000495027.1
ENST00000389536.4
DNAH12



dynein, axonemal, heavy chain 12



chr1_-_169396666 1.359 ENST00000456107.1
ENST00000367805.3
CCDC181

coiled-coil domain containing 181

chr21_-_46340884 1.334 ENST00000302347.5
ENST00000517819.1
ITGB2

integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

chr2_+_61293021 1.258 ENST00000402291.1
KIAA1841
KIAA1841
chr1_-_169396646 1.245 ENST00000367806.3
CCDC181
coiled-coil domain containing 181
chr1_+_174844645 1.241 ENST00000486220.1
RABGAP1L
RAB GTPase activating protein 1-like
chr20_+_43211149 1.230 ENST00000372886.1
PKIG
protein kinase (cAMP-dependent, catalytic) inhibitor gamma
chr8_+_67976593 1.174 ENST00000262210.5
ENST00000412460.1
CSPP1

centrosome and spindle pole associated protein 1

chr4_+_36283213 1.141 ENST00000357504.3
DTHD1
death domain containing 1
chr2_-_220110187 1.116 ENST00000295759.7
ENST00000392089.2
GLB1L

galactosidase, beta 1-like

chr2_-_62081148 1.114 ENST00000404929.1
FAM161A
family with sequence similarity 161, member A
chr2_-_220110111 1.113 ENST00000428427.1
ENST00000356283.3
ENST00000432839.1
ENST00000424620.1
GLB1L



galactosidase, beta 1-like



chr2_-_62081254 1.107 ENST00000405894.3
FAM161A
family with sequence similarity 161, member A
chr7_-_120498357 1.076 ENST00000415871.1
ENST00000222747.3
ENST00000430985.1
TSPAN12


tetraspanin 12


chr12_-_113658892 1.058 ENST00000299732.2
ENST00000416617.2
IQCD

IQ motif containing D

chrX_-_10851762 1.038 ENST00000380785.1
ENST00000380787.1
MID1

midline 1 (Opitz/BBB syndrome)

chr11_+_100862811 0.941 ENST00000303130.2
TMEM133
transmembrane protein 133
chr7_+_100728720 0.937 ENST00000306085.6
ENST00000412507.1
TRIM56

tripartite motif containing 56

chr22_-_37172111 0.924 ENST00000417951.2
ENST00000430701.1
ENST00000433985.2
IFT27


intraflagellar transport 27 homolog (Chlamydomonas)


chr22_-_37172191 0.890 ENST00000340630.5
IFT27
intraflagellar transport 27 homolog (Chlamydomonas)
chr18_-_53253323 0.877 ENST00000540999.1
ENST00000563888.2
TCF4

transcription factor 4

chr8_-_28347737 0.872 ENST00000517673.1
ENST00000518734.1
ENST00000346498.2
ENST00000380254.2
FBXO16



F-box protein 16



chr12_-_56236734 0.866 ENST00000548629.1
MMP19
matrix metallopeptidase 19
chr1_-_86861660 0.865 ENST00000486215.1
ODF2L
outer dense fiber of sperm tails 2-like
chr4_-_110723134 0.858 ENST00000510800.1
ENST00000512148.1
CFI

complement factor I

chr14_+_45431379 0.851 ENST00000361577.3
ENST00000361462.2
ENST00000382233.2
FAM179B


family with sequence similarity 179, member B


chr4_-_110723194 0.837 ENST00000394635.3
CFI
complement factor I
chr1_-_217311090 0.825 ENST00000493603.1
ENST00000366940.2
ESRRG

estrogen-related receptor gamma

chrX_+_16964985 0.803 ENST00000303843.7
REPS2
RALBP1 associated Eps domain containing 2
chr17_+_26800648 0.789 ENST00000545060.1
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr17_+_26800756 0.783 ENST00000537681.1
SLC13A2
solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2
chr6_-_52710893 0.772 ENST00000284562.2
GSTA5
glutathione S-transferase alpha 5
chr6_+_30951487 0.741 ENST00000486149.2
ENST00000376296.3
MUC21

mucin 21, cell surface associated

chr10_-_112678904 0.704 ENST00000423273.1
ENST00000436562.1
ENST00000447005.1
ENST00000454061.1
BBIP1



BBSome interacting protein 1



chr17_+_26800296 0.686 ENST00000444914.3
ENST00000314669.5
SLC13A2

solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2

chr1_-_150669500 0.673 ENST00000271732.3
GOLPH3L
golgi phosphoprotein 3-like
chr1_+_153940713 0.636 ENST00000368601.1
ENST00000368603.1
ENST00000368600.3
CREB3L4


cAMP responsive element binding protein 3-like 4


chr6_+_27114861 0.626 ENST00000377459.1
HIST1H2AH
histone cluster 1, H2ah
chr6_-_52628271 0.617 ENST00000493422.1
GSTA2
glutathione S-transferase alpha 2
chr1_-_217250231 0.605 ENST00000493748.1
ENST00000463665.1
ESRRG

estrogen-related receptor gamma

chr14_+_50999744 0.594 ENST00000441560.2
ATL1
atlastin GTPase 1
chr1_+_27561007 0.586 ENST00000319394.3
WDTC1
WD and tetratricopeptide repeats 1
chr6_+_46097711 0.570 ENST00000321037.4
ENPP4
ectonucleotide pyrophosphatase/phosphodiesterase 4 (putative)
chr17_+_48172639 0.560 ENST00000503176.1
ENST00000503614.1
PDK2

pyruvate dehydrogenase kinase, isozyme 2

chr5_+_140254884 0.551 ENST00000398631.2
PCDHA12
protocadherin alpha 12
chr6_-_165989936 0.545 ENST00000354448.4
PDE10A
phosphodiesterase 10A
chr1_-_86861936 0.534 ENST00000394733.2
ENST00000359242.3
ENST00000294678.2
ENST00000479890.1
ENST00000317336.7
ENST00000370567.1
ENST00000394731.1
ENST00000478286.2
ENST00000370566.3
ODF2L








outer dense fiber of sperm tails 2-like








chr14_-_89878369 0.523 ENST00000553840.1
ENST00000556916.1
FOXN3

forkhead box N3

chrX_-_10588459 0.520 ENST00000380782.2
MID1
midline 1 (Opitz/BBB syndrome)
chr6_-_15586238 0.467 ENST00000462989.2
DTNBP1
dystrobrevin binding protein 1
chrX_-_10588595 0.454 ENST00000423614.1
ENST00000317552.4
MID1

midline 1 (Opitz/BBB syndrome)

chr2_+_24714729 0.447 ENST00000406961.1
ENST00000405141.1
NCOA1

nuclear receptor coactivator 1

chrX_-_115594160 0.437 ENST00000371894.4
CXorf61
cancer/testis antigen 83
chr2_-_197226875 0.420 ENST00000409111.1
HECW2
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
chr1_+_109255279 0.410 ENST00000370017.3
FNDC7
fibronectin type III domain containing 7
chr16_-_30597000 0.399 ENST00000470110.1
ENST00000395216.2
ZNF785

zinc finger protein 785

chr1_+_222988464 0.388 ENST00000420335.1
RP11-452F19.3
RP11-452F19.3
chr12_-_56727676 0.382 ENST00000547572.1
ENST00000257931.5
ENST00000440411.3
PAN2


PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)


chr17_-_56609302 0.379 ENST00000581607.1
ENST00000317256.6
ENST00000426861.1
ENST00000580809.1
ENST00000577729.1
ENST00000583291.1
SEPT4





septin 4





chr7_-_47579188 0.373 ENST00000398879.1
ENST00000355730.3
ENST00000442536.2
ENST00000458317.2
TNS3



tensin 3



chr3_-_69101461 0.372 ENST00000543976.1
TMF1
TATA element modulatory factor 1
chr17_-_29641084 0.372 ENST00000544462.1
EVI2B
ecotropic viral integration site 2B
chr1_+_222988363 0.371 ENST00000450784.1
ENST00000426045.1
ENST00000457955.1
ENST00000444858.1
ENST00000435378.1
ENST00000441676.1
RP11-452F19.3





RP11-452F19.3





chr15_+_75639296 0.371 ENST00000564500.1
ENST00000355059.4
ENST00000566752.1
NEIL1


nei endonuclease VIII-like 1 (E. coli)


chr3_-_69101413 0.367 ENST00000398559.2
TMF1
TATA element modulatory factor 1
chr3_+_52444651 0.352 ENST00000327906.3
PHF7
PHD finger protein 7
chr8_+_27491572 0.347 ENST00000301904.3
SCARA3
scavenger receptor class A, member 3
chr5_+_131705438 0.346 ENST00000245407.3
SLC22A5
solute carrier family 22 (organic cation/carnitine transporter), member 5
chr20_+_42187682 0.341 ENST00000373092.3
ENST00000373077.1
SGK2

serum/glucocorticoid regulated kinase 2

chr17_+_3118915 0.333 ENST00000304094.1
OR1A1
olfactory receptor, family 1, subfamily A, member 1
chr1_+_27561104 0.330 ENST00000361771.3
WDTC1
WD and tetratricopeptide repeats 1
chr10_-_112678976 0.328 ENST00000448814.1
BBIP1
BBSome interacting protein 1
chr12_-_56727487 0.324 ENST00000548043.1
ENST00000425394.2
PAN2

PAN2 poly(A) specific ribonuclease subunit homolog (S. cerevisiae)

chr3_+_69928256 0.318 ENST00000394355.2
MITF
microphthalmia-associated transcription factor
chr4_+_25915896 0.315 ENST00000514384.1
SMIM20
small integral membrane protein 20
chr6_-_26199471 0.313 ENST00000341023.1
HIST1H2AD
histone cluster 1, H2ad
chr4_+_25915822 0.312 ENST00000506197.2
SMIM20
small integral membrane protein 20
chr1_-_93257951 0.312 ENST00000543509.1
ENST00000370331.1
ENST00000540033.1
EVI5


ecotropic viral integration site 5


chr14_-_23755297 0.308 ENST00000357460.5
HOMEZ
homeobox and leucine zipper encoding
chr11_+_19798964 0.302 ENST00000527559.2
NAV2
neuron navigator 2
chr9_+_33290491 0.296 ENST00000379540.3
ENST00000379521.4
ENST00000318524.6
NFX1


nuclear transcription factor, X-box binding 1


chrX_+_70752917 0.287 ENST00000373719.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr2_+_128458514 0.286 ENST00000310981.4
SFT2D3
SFT2 domain containing 3
chr2_+_127413481 0.285 ENST00000259254.4
GYPC
glycophorin C (Gerbich blood group)
chr6_-_112408661 0.268 ENST00000368662.5
TUBE1
tubulin, epsilon 1
chr19_-_7553852 0.268 ENST00000593547.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chr17_-_62493131 0.267 ENST00000539111.2
POLG2
polymerase (DNA directed), gamma 2, accessory subunit
chr1_+_196743943 0.266 ENST00000471440.2
ENST00000391985.3
CFHR3

complement factor H-related 3

chr20_+_42187608 0.265 ENST00000373100.1
SGK2
serum/glucocorticoid regulated kinase 2
chr1_+_109632425 0.263 ENST00000338272.8
TMEM167B
transmembrane protein 167B
chrX_-_99987088 0.258 ENST00000372981.1
ENST00000263033.5
SYTL4

synaptotagmin-like 4

chr12_+_94071341 0.257 ENST00000542893.2
CRADD
CASP2 and RIPK1 domain containing adaptor with death domain
chr1_+_151043070 0.257 ENST00000368918.3
ENST00000368917.1
GABPB2

GA binding protein transcription factor, beta subunit 2

chr2_+_68384976 0.256 ENST00000263657.2
PNO1
partner of NOB1 homolog (S. cerevisiae)
chr8_+_120885949 0.253 ENST00000523492.1
ENST00000286234.5
DEPTOR

DEP domain containing MTOR-interacting protein

chr19_-_7553889 0.252 ENST00000221480.1
PEX11G
peroxisomal biogenesis factor 11 gamma
chr11_-_124981475 0.247 ENST00000532156.1
ENST00000532407.1
ENST00000279968.4
ENST00000527766.1
ENST00000529583.1
ENST00000524373.1
ENST00000527271.1
ENST00000526175.1
ENST00000529609.1
ENST00000533273.1
ENST00000531909.1
ENST00000529530.1
TMEM218











transmembrane protein 218











chr12_+_104982622 0.245 ENST00000549016.1
CHST11
carbohydrate (chondroitin 4) sulfotransferase 11
chr15_+_78830023 0.244 ENST00000599596.1
AC027228.1
HCG2005369; Uncharacterized protein
chr5_+_173316341 0.243 ENST00000520867.1
ENST00000334035.5
CPEB4

cytoplasmic polyadenylation element binding protein 4

chr10_+_24755416 0.240 ENST00000396446.1
ENST00000396445.1
ENST00000376451.2
KIAA1217


KIAA1217


chr1_+_206643787 0.237 ENST00000367120.3
IKBKE
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase epsilon
chr14_+_56078695 0.235 ENST00000416613.1
KTN1
kinectin 1 (kinesin receptor)
chr6_+_1080164 0.234 ENST00000314040.1
AL033381.1
Uncharacterized protein; cDNA FLJ34594 fis, clone KIDNE2009109
chr17_-_27621125 0.232 ENST00000579665.1
ENST00000225388.4
NUFIP2

nuclear fragile X mental retardation protein interacting protein 2

chr11_-_5207612 0.231 ENST00000380367.1
OR52A1
olfactory receptor, family 52, subfamily A, member 1
chr18_-_32870148 0.227 ENST00000589178.1
ENST00000333206.5
ENST00000592278.1
ENST00000592211.1
ENST00000420878.3
ENST00000383091.2
ENST00000586922.2
ZSCAN30





RP11-158H5.7
zinc finger and SCAN domain containing 30





RP11-158H5.7
chr5_+_178977546 0.218 ENST00000319449.4
ENST00000377001.2
RUFY1

RUN and FYVE domain containing 1

chr4_-_186877502 0.217 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2


sorbin and SH3 domain containing 2


chr18_-_19283649 0.217 ENST00000584464.1
ENST00000578270.1
ABHD3

abhydrolase domain containing 3

chr5_+_110559603 0.212 ENST00000512453.1
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr14_+_32030582 0.204 ENST00000550649.1
ENST00000281081.7
NUBPL

nucleotide binding protein-like

chr1_+_196743912 0.203 ENST00000367425.4
CFHR3
complement factor H-related 3
chr19_+_41699135 0.199 ENST00000542619.1
ENST00000600561.1
CYP2S1

cytochrome P450, family 2, subfamily S, polypeptide 1

chr1_+_198126093 0.199 ENST00000367385.4
ENST00000442588.1
ENST00000538004.1
NEK7


NIMA-related kinase 7


chr1_-_159046617 0.198 ENST00000368130.4
AIM2
absent in melanoma 2
chr8_+_66955648 0.198 ENST00000522619.1
DNAJC5B
DnaJ (Hsp40) homolog, subfamily C, member 5 beta
chr10_+_89419370 0.192 ENST00000361175.4
ENST00000456849.1
PAPSS2

3'-phosphoadenosine 5'-phosphosulfate synthase 2

chr12_-_54673871 0.192 ENST00000209875.4
CBX5
chromobox homolog 5
chr1_+_100436065 0.191 ENST00000370153.1
SLC35A3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member A3
chr13_+_111365602 0.190 ENST00000333219.7
ING1
inhibitor of growth family, member 1
chr9_-_101984184 0.183 ENST00000476832.1
ALG2
ALG2, alpha-1,3/1,6-mannosyltransferase
chr3_-_151176497 0.183 ENST00000282466.3
IGSF10
immunoglobulin superfamily, member 10
chr8_-_95220775 0.182 ENST00000441892.2
ENST00000521491.1
ENST00000027335.3
CDH17


cadherin 17, LI cadherin (liver-intestine)


chr3_+_37035289 0.182 ENST00000455445.2
ENST00000441265.1
ENST00000435176.1
ENST00000429117.1
ENST00000536378.1
MLH1




mutL homolog 1




chr19_-_53238260 0.178 ENST00000453741.2
ENST00000602162.1
ENST00000601643.1
ENST00000596702.1
ENST00000600943.1
ENST00000543227.1
ENST00000540744.1
ZNF611






zinc finger protein 611






chr2_+_109335929 0.178 ENST00000283195.6
RANBP2
RAN binding protein 2
chr14_+_31028348 0.175 ENST00000550944.1
ENST00000438909.2
ENST00000553504.1
G2E3


G2/M-phase specific E3 ubiquitin protein ligase


chr14_+_31028329 0.175 ENST00000206595.6
G2E3
G2/M-phase specific E3 ubiquitin protein ligase
chrX_+_70586082 0.175 ENST00000373790.4
ENST00000449580.1
ENST00000423759.1
TAF1


TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa


chrX_+_22291065 0.170 ENST00000323684.1
ZNF645
zinc finger protein 645
chr14_+_105331596 0.169 ENST00000556508.1
ENST00000414716.3
ENST00000453495.1
ENST00000418279.1
CEP170B



centrosomal protein 170B



chr10_+_115312766 0.169 ENST00000351270.3
HABP2
hyaluronan binding protein 2
chr6_+_30585486 0.163 ENST00000259873.4
ENST00000506373.2
MRPS18B

mitochondrial ribosomal protein S18B

chr12_-_53715328 0.161 ENST00000547757.1
ENST00000394384.3
ENST00000209873.4
AAAS


achalasia, adrenocortical insufficiency, alacrimia


chrX_+_66764375 0.160 ENST00000374690.3
AR
androgen receptor
chr11_+_17281900 0.159 ENST00000530527.1
NUCB2
nucleobindin 2
chr8_-_38326139 0.159 ENST00000335922.5
ENST00000532791.1
ENST00000397091.5
FGFR1


fibroblast growth factor receptor 1


chr11_-_59950519 0.155 ENST00000528851.1
MS4A6A
membrane-spanning 4-domains, subfamily A, member 6A
chr7_-_22234381 0.154 ENST00000458533.1
RAPGEF5
Rap guanine nucleotide exchange factor (GEF) 5
chr10_+_35484793 0.152 ENST00000488741.1
ENST00000474931.1
ENST00000468236.1
ENST00000344351.5
ENST00000490511.1
CREM




cAMP responsive element modulator




chr6_-_26199499 0.152 ENST00000377831.5
HIST1H3D
histone cluster 1, H3d
chr8_-_116504448 0.150 ENST00000518018.1
TRPS1
trichorhinophalangeal syndrome I
chr12_+_51633061 0.143 ENST00000551313.1
DAZAP2
DAZ associated protein 2
chr11_-_62572901 0.141 ENST00000439713.2
ENST00000531131.1
ENST00000530875.1
ENST00000531709.2
ENST00000294172.2
NXF1




nuclear RNA export factor 1




chr17_-_55822653 0.139 ENST00000299415.2
AC007431.1
coiled-coil domain containing 182
chr1_-_160549235 0.138 ENST00000368054.3
ENST00000368048.3
ENST00000311224.4
ENST00000368051.3
ENST00000534968.1
CD84




CD84 molecule




chr3_-_12587055 0.138 ENST00000564146.3
C3orf83
chromosome 3 open reading frame 83
chr3_-_45837959 0.137 ENST00000353278.4
ENST00000456124.2
SLC6A20

solute carrier family 6 (proline IMINO transporter), member 20

chrX_+_70586140 0.137 ENST00000276072.3
TAF1
TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa
chr11_-_46638720 0.134 ENST00000326737.3
HARBI1
harbinger transposase derived 1
chr11_-_47447970 0.125 ENST00000298852.3
ENST00000530912.1
PSMC3

proteasome (prosome, macropain) 26S subunit, ATPase, 3

chr19_+_50084561 0.119 ENST00000246794.5
PRRG2
proline rich Gla (G-carboxyglutamic acid) 2
chrX_+_70752945 0.118 ENST00000373701.3
OGT
O-linked N-acetylglucosamine (GlcNAc) transferase
chr12_-_122018859 0.117 ENST00000536437.1
ENST00000377071.4
ENST00000538046.2
KDM2B


lysine (K)-specific demethylase 2B


chr8_+_107738240 0.116 ENST00000449762.2
ENST00000297447.6
OXR1

oxidation resistance 1

chr5_-_133968459 0.116 ENST00000505758.1
ENST00000439578.1
ENST00000502286.1
SAR1B


SAR1 homolog B (S. cerevisiae)


chr14_-_45431091 0.114 ENST00000579157.1
ENST00000396128.4
ENST00000556500.1
KLHL28


kelch-like family member 28


chr1_+_175036966 0.113 ENST00000239462.4
TNN
tenascin N
chr5_-_39074479 0.113 ENST00000514735.1
ENST00000296782.5
ENST00000357387.3
RICTOR


RPTOR independent companion of MTOR, complex 2


chrM_+_5824 0.112 ENST00000361624.2
MT-CO1
mitochondrially encoded cytochrome c oxidase I
chr6_+_29364416 0.106 ENST00000383555.2
OR12D2
olfactory receptor, family 12, subfamily D, member 2 (gene/pseudogene)
chr3_-_57326704 0.105 ENST00000487349.1
ENST00000389601.3
ASB14

ankyrin repeat and SOCS box containing 14

chr3_+_38347427 0.102 ENST00000273173.4
SLC22A14
solute carrier family 22, member 14
chr14_+_37641012 0.098 ENST00000556667.1
SLC25A21-AS1
SLC25A21 antisense RNA 1
chr12_-_49488573 0.095 ENST00000266991.2
DHH
desert hedgehog
chr1_-_149982624 0.094 ENST00000417191.1
ENST00000369135.4
OTUD7B

OTU domain containing 7B

chr16_+_21689835 0.093 ENST00000286149.4
ENST00000388958.3
OTOA

otoancorin

chrX_-_153523462 0.090 ENST00000361930.3
ENST00000369926.1
TEX28

testis expressed 28

chr9_-_114246635 0.090 ENST00000338205.5
KIAA0368
KIAA0368
chr5_+_110559784 0.088 ENST00000282356.4
CAMK4
calcium/calmodulin-dependent protein kinase IV
chr2_-_3521518 0.087 ENST00000382093.5
ADI1
acireductone dioxygenase 1
chr2_+_106468204 0.087 ENST00000425756.1
ENST00000393349.2
NCK2

NCK adaptor protein 2

chr13_-_67802549 0.087 ENST00000328454.5
ENST00000377865.2
PCDH9

protocadherin 9

chr11_+_10772534 0.084 ENST00000361367.2
CTR9
CTR9, Paf1/RNA polymerase II complex component
chr4_-_69434245 0.082 ENST00000317746.2
UGT2B17
UDP glucuronosyltransferase 2 family, polypeptide B17
chr7_+_101460882 0.080 ENST00000292535.7
ENST00000549414.2
ENST00000550008.2
ENST00000546411.2
ENST00000556210.1
CUX1




cut-like homeobox 1




chr3_-_45838011 0.079 ENST00000358525.4
ENST00000413781.1
SLC6A20

solute carrier family 6 (proline IMINO transporter), member 20

chr5_+_138629417 0.078 ENST00000510056.1
ENST00000511249.1
ENST00000503811.1
ENST00000511378.1
MATR3



matrin 3



chr11_+_34643600 0.078 ENST00000530286.1
ENST00000533754.1
EHF

ets homologous factor

chr17_-_56494908 0.078 ENST00000577716.1
RNF43
ring finger protein 43
chr5_-_157079372 0.076 ENST00000311371.5
SOX30
SRY (sex determining region Y)-box 30
chr11_-_59950486 0.075 ENST00000426738.2
ENST00000533023.1
ENST00000420732.2
MS4A6A


membrane-spanning 4-domains, subfamily A, member 6A


chr17_-_29641104 0.073 ENST00000577894.1
ENST00000330927.4
EVI2B

ecotropic viral integration site 2B

chr3_-_126327398 0.073 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr5_-_157079428 0.071 ENST00000265007.6
SOX30
SRY (sex determining region Y)-box 30
chr12_+_28343365 0.070 ENST00000545336.1
CCDC91
coiled-coil domain containing 91
chrX_+_135730373 0.070 ENST00000370628.2
CD40LG
CD40 ligand
chr2_+_220110177 0.069 ENST00000409638.3
ENST00000396738.2
ENST00000409516.3
STK16


serine/threonine kinase 16


chr19_+_50353944 0.068 ENST00000594151.1
ENST00000600603.1
ENST00000601638.1
ENST00000221557.9
PTOV1



prostate tumor overexpressed 1



chr2_-_86948245 0.066 ENST00000439940.2
ENST00000604011.1
CHMP3
RNF103-CHMP3
charged multivesicular body protein 3
RNF103-CHMP3 readthrough

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0045925 positive regulation of female receptivity(GO:0045925)
0.1 0.7 GO:0035936 testosterone secretion(GO:0035936) regulation of testosterone secretion(GO:2000843) positive regulation of testosterone secretion(GO:2000845)
0.1 0.6 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 2.0 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 1.0 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.1 0.9 GO:0001554 luteolysis(GO:0001554)
0.1 1.8 GO:0043651 linoleic acid metabolic process(GO:0043651)
0.1 0.4 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.5 GO:0044375 regulation of peroxisome size(GO:0044375)
0.1 0.2 GO:1990569 UDP-N-acetylglucosamine transport(GO:0015788) UDP-N-acetylglucosamine transmembrane transport(GO:1990569)
0.1 0.3 GO:0036369 transcription factor catabolic process(GO:0036369)
0.1 0.2 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic spindle midzone assembly(GO:0051257) meiotic metaphase plate congression(GO:0051311)
0.1 0.7 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 0.3 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 1.1 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 1.8 GO:0060122 inner ear receptor stereocilium organization(GO:0060122)
0.1 0.2 GO:0060599 lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599)
0.0 0.2 GO:0000103 sulfate assimilation(GO:0000103)
0.0 1.2 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.2 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.9 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.3 GO:0021564 vagus nerve development(GO:0021564)
0.0 0.3 GO:0002371 dendritic cell cytokine production(GO:0002371)
0.0 0.3 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.1 GO:0032661 regulation of interleukin-18 production(GO:0032661)
0.0 0.3 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.5 GO:0060155 platelet dense granule organization(GO:0060155)
0.0 0.4 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 1.1 GO:0010842 retina layer formation(GO:0010842)
0.0 0.6 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160) positive regulation of histone H3-K79 methylation(GO:2001162)
0.0 0.6 GO:0006152 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0 0.5 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 1.6 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.2 GO:0070269 pyroptosis(GO:0070269)
0.0 0.4 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 1.1 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.2 GO:0015824 proline transport(GO:0015824)
0.0 0.1 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.0 0.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.3 GO:0009650 UV protection(GO:0009650)
0.0 0.5 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.9 GO:0070534 protein K63-linked ubiquitination(GO:0070534)
0.0 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.1 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493)
0.0 0.0 GO:0007037 vacuolar phosphate transport(GO:0007037) positive regulation of mitotic cell cycle DNA replication(GO:1903465) positive regulation of parathyroid hormone secretion(GO:2000830)
0.0 0.7 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 1.8 GO:0006835 dicarboxylic acid transport(GO:0006835)
0.0 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 0.1 GO:0090160 Golgi to lysosome transport(GO:0090160)
0.0 0.1 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 1.4 GO:0001942 hair follicle development(GO:0001942)
0.0 0.4 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.6 GO:0002177 manchette(GO:0002177)
0.2 0.7 GO:0031251 PAN complex(GO:0031251)
0.2 1.3 GO:0034688 integrin alphaM-beta2 complex(GO:0034688)
0.1 0.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.3 GO:0000229 cytoplasmic chromosome(GO:0000229)
0.1 1.0 GO:0034464 BBSome(GO:0034464)
0.1 1.6 GO:0097225 sperm midpiece(GO:0097225)
0.1 0.2 GO:0005715 late recombination nodule(GO:0005715)
0.1 0.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 2.2 GO:0032391 photoreceptor connecting cilium(GO:0032391)
0.0 0.4 GO:0097227 sperm annulus(GO:0097227)
0.0 0.2 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.5 GO:0045009 melanosome membrane(GO:0033162) chitosome(GO:0045009)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 1.4 GO:0030286 dynein complex(GO:0030286)
0.0 1.3 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0015361 low-affinity sodium:dicarboxylate symporter activity(GO:0015361)
0.2 2.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.2 1.4 GO:0050682 AF-2 domain binding(GO:0050682)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 1.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.4 GO:0097363 protein N-acetylglucosaminyltransferase activity(GO:0016262) protein O-GlcNAc transferase activity(GO:0097363)
0.1 0.3 GO:0036435 K48-linked polyubiquitin binding(GO:0036435)
0.1 0.5 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.2 GO:0050659 N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659)
0.1 0.3 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 0.9 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.2 GO:0004781 adenylylsulfate kinase activity(GO:0004020) sulfate adenylyltransferase activity(GO:0004779) sulfate adenylyltransferase (ATP) activity(GO:0004781)
0.1 0.2 GO:0005462 UDP-N-acetylglucosamine transmembrane transporter activity(GO:0005462)
0.1 0.3 GO:0001083 transcription factor activity, RNA polymerase II basal transcription factor binding(GO:0001083)
0.1 1.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 0.3 GO:0008401 retinoic acid 4-hydroxylase activity(GO:0008401)
0.0 0.2 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.2 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 1.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.1 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 1.4 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.7 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.1 GO:0010309 acireductone dioxygenase [iron(II)-requiring] activity(GO:0010309)
0.0 0.4 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.2 GO:0004882 androgen receptor activity(GO:0004882)
0.0 0.6 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.0 1.8 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.8 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.4 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 0.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.5 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.3 GO:0070513 death domain binding(GO:0070513)
0.0 0.1 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 1.7 GO:0051219 phosphoprotein binding(GO:0051219)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID_INTEGRIN_CS_PATHWAY Integrin family cell surface interactions
0.0 0.4 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.2 PID_RANBP2_PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.6 PID_AR_PATHWAY Coregulation of Androgen receptor activity

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 REACTOME_BILE_SALT_AND_ORGANIC_ANION_SLC_TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.1 2.0 REACTOME_REGULATION_OF_COMPLEMENT_CASCADE Genes involved in Regulation of Complement cascade
0.1 3.2 REACTOME_GLUTATHIONE_CONJUGATION Genes involved in Glutathione conjugation
0.0 0.7 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME_REGULATION_OF_PYRUVATE_DEHYDROGENASE_PDH_COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.4 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 1.4 REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.3 REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.2 REACTOME_MEIOSIS Genes involved in Meiosis
0.0 0.6 REACTOME_MYOGENESIS Genes involved in Myogenesis
0.0 1.2 REACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell