Motif ID: HOXD1

Z-value: 0.479


Transcription factors associated with HOXD1:

Gene SymbolEntrez IDGene Name
HOXD1 ENSG00000128645.11 HOXD1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXD1hg19_v2_chr2_+_177053307_177053402-0.395.7e-02Click!


Activity profile for motif HOXD1.

activity profile for motif HOXD1


Sorted Z-values histogram for motif HOXD1

Sorted Z-values for motif HOXD1



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXD1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_+_101918153 2.452 ENST00000434758.2
ENST00000526781.1
ENST00000534360.1
C11orf70


chromosome 11 open reading frame 70


chr13_+_36050881 2.018 ENST00000537702.1
NBEA
neurobeachin
chr2_+_228736335 1.711 ENST00000440997.1
ENST00000545118.1
DAW1

dynein assembly factor with WDR repeat domains 1

chr11_+_71900703 1.353 ENST00000393681.2
FOLR1
folate receptor 1 (adult)
chr11_+_71900572 1.319 ENST00000312293.4
FOLR1
folate receptor 1 (adult)
chr11_-_26593779 1.142 ENST00000529533.1
MUC15
mucin 15, cell surface associated
chr4_-_25865159 0.818 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr11_-_26593649 0.808 ENST00000455601.2
MUC15
mucin 15, cell surface associated
chr5_-_96478466 0.806 ENST00000274382.4
LIX1
Lix1 homolog (chicken)
chr7_+_133812052 0.727 ENST00000285928.2
LRGUK
leucine-rich repeats and guanylate kinase domain containing
chr11_-_26593677 0.686 ENST00000527569.1
MUC15
mucin 15, cell surface associated
chr14_+_74034310 0.649 ENST00000538782.1
ACOT2
acyl-CoA thioesterase 2
chr20_-_50418972 0.562 ENST00000395997.3
SALL4
spalt-like transcription factor 4
chr9_-_5339873 0.541 ENST00000223862.1
ENST00000223858.4
RLN1

relaxin 1

chrX_+_77154935 0.531 ENST00000481445.1
COX7B
cytochrome c oxidase subunit VIIb
chr20_-_50418947 0.527 ENST00000371539.3
SALL4
spalt-like transcription factor 4
chr20_-_50419055 0.512 ENST00000217086.4
SALL4
spalt-like transcription factor 4
chr20_+_43990576 0.482 ENST00000372727.1
ENST00000414310.1
SYS1

SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)

chr7_+_99717230 0.473 ENST00000262932.3
CNPY4
canopy FGF signaling regulator 4
chrX_+_77166172 0.470 ENST00000343533.5
ENST00000350425.4
ENST00000341514.6
ATP7A


ATPase, Cu++ transporting, alpha polypeptide


chr15_-_37393406 0.456 ENST00000338564.5
ENST00000558313.1
ENST00000340545.5
MEIS2


Meis homeobox 2


chr4_-_74486109 0.421 ENST00000395777.2
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr4_-_138453559 0.416 ENST00000511115.1
PCDH18
protocadherin 18
chr11_-_102651343 0.407 ENST00000279441.4
ENST00000539681.1
MMP10

matrix metallopeptidase 10 (stromelysin 2)

chr12_-_23737534 0.393 ENST00000396007.2
SOX5
SRY (sex determining region Y)-box 5
chr4_-_150736962 0.370 ENST00000502345.1
ENST00000510975.1
ENST00000511993.1
RP11-526A4.1


RP11-526A4.1


chr12_+_109577202 0.368 ENST00000377848.3
ENST00000377854.5
ACACB

acetyl-CoA carboxylase beta

chr5_-_20575959 0.331 ENST00000507958.1
CDH18
cadherin 18, type 2
chr16_+_53133070 0.312 ENST00000565832.1
CHD9
chromodomain helicase DNA binding protein 9
chr4_-_74486347 0.280 ENST00000342081.3
RASSF6
Ras association (RalGDS/AF-6) domain family member 6
chr1_-_151431647 0.270 ENST00000368863.2
ENST00000409503.1
ENST00000491586.1
ENST00000533351.1
ENST00000540984.1
POGZ




pogo transposable element with ZNF domain




chr10_-_27529486 0.249 ENST00000375888.1
ACBD5
acyl-CoA binding domain containing 5
chr19_+_50016610 0.241 ENST00000596975.1
FCGRT
Fc fragment of IgG, receptor, transporter, alpha
chr4_+_113568207 0.238 ENST00000511529.1
LARP7
La ribonucleoprotein domain family, member 7
chr10_-_72142345 0.236 ENST00000373224.1
ENST00000446961.1
ENST00000358141.2
ENST00000357631.2
LRRC20



leucine rich repeat containing 20



chr13_+_78315295 0.232 ENST00000351546.3
SLAIN1
SLAIN motif family, member 1
chr11_-_62521614 0.217 ENST00000527994.1
ENST00000394807.3
ZBTB3

zinc finger and BTB domain containing 3

chr3_+_2933893 0.211 ENST00000397459.2
CNTN4
contactin 4
chr1_-_151431909 0.201 ENST00000361398.3
ENST00000271715.2
POGZ

pogo transposable element with ZNF domain

chr3_+_111717600 0.192 ENST00000273368.4
TAGLN3
transgelin 3
chr3_+_111717511 0.176 ENST00000478951.1
ENST00000393917.2
TAGLN3

transgelin 3

chr7_-_73256838 0.175 ENST00000297873.4
WBSCR27
Williams Beuren syndrome chromosome region 27
chr3_+_111718173 0.172 ENST00000494932.1
TAGLN3
transgelin 3
chr3_+_111718036 0.169 ENST00000455401.2
TAGLN3
transgelin 3
chr8_+_55528627 0.161 ENST00000220676.1
RP1
retinitis pigmentosa 1 (autosomal dominant)
chr1_-_112032284 0.154 ENST00000414219.1
ADORA3
adenosine A3 receptor
chr4_-_138453606 0.150 ENST00000412923.2
ENST00000344876.4
ENST00000507846.1
ENST00000510305.1
PCDH18



protocadherin 18



chr4_-_74486217 0.140 ENST00000335049.5
ENST00000307439.5
RASSF6

Ras association (RalGDS/AF-6) domain family member 6

chr1_-_232651312 0.139 ENST00000262861.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr3_-_191000172 0.123 ENST00000427544.2
UTS2B
urotensin 2B
chr11_+_73498898 0.105 ENST00000535529.1
ENST00000497094.2
ENST00000411840.2
ENST00000535277.1
ENST00000398483.3
ENST00000542303.1
MRPL48





mitochondrial ribosomal protein L48





chr12_+_29376673 0.103 ENST00000547116.1
FAR2
fatty acyl CoA reductase 2
chr7_-_99717463 0.099 ENST00000437822.2
TAF6
TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa
chr17_+_18086392 0.095 ENST00000541285.1
ALKBH5
alkB, alkylation repair homolog 5 (E. coli)
chr12_+_29376592 0.094 ENST00000182377.4
FAR2
fatty acyl CoA reductase 2
chr3_-_126327398 0.092 ENST00000383572.2
TXNRD3NB
thioredoxin reductase 3 neighbor
chr11_-_95657231 0.089 ENST00000409459.1
ENST00000352297.7
ENST00000393223.3
ENST00000346299.5
MTMR2



myotubularin related protein 2



chr5_+_63802109 0.087 ENST00000334025.2
RGS7BP
regulator of G-protein signaling 7 binding protein
chr2_+_54350316 0.086 ENST00000606865.1
ACYP2
acylphosphatase 2, muscle type
chr1_-_190446759 0.085 ENST00000367462.3
BRINP3
bone morphogenetic protein/retinoic acid inducible neural-specific 3
chr4_+_86749045 0.078 ENST00000514229.1
ARHGAP24
Rho GTPase activating protein 24
chr4_+_86748898 0.078 ENST00000509300.1
ARHGAP24
Rho GTPase activating protein 24
chr7_+_148287657 0.064 ENST00000307003.2
C7orf33
chromosome 7 open reading frame 33
chr7_-_99716952 0.061 ENST00000523306.1
ENST00000344095.4
ENST00000417349.1
ENST00000493322.1
ENST00000520135.1
ENST00000418432.2
ENST00000460673.2
ENST00000452041.1
ENST00000452438.2
ENST00000451699.1
ENST00000453269.2
TAF6










TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 80kDa










chr11_-_71823266 0.058 ENST00000538919.1
ENST00000539395.1
ENST00000542531.1
ANAPC15


anaphase promoting complex subunit 15


chr11_-_71823796 0.056 ENST00000545680.1
ENST00000543587.1
ENST00000538393.1
ENST00000535234.1
ENST00000227618.4
ENST00000535503.1
ANAPC15





anaphase promoting complex subunit 15





chr5_+_148737562 0.052 ENST00000274569.4
PCYOX1L
prenylcysteine oxidase 1 like
chr17_-_10372875 0.039 ENST00000255381.2
MYH4
myosin, heavy chain 4, skeletal muscle
chr18_-_33709268 0.037 ENST00000269187.5
ENST00000590986.1
ENST00000440549.2
SLC39A6


solute carrier family 39 (zinc transporter), member 6


chr11_-_71823715 0.019 ENST00000545944.1
ENST00000502597.2
ANAPC15

anaphase promoting complex subunit 15

chr1_-_92952433 0.019 ENST00000294702.5
GFI1
growth factor independent 1 transcription repressor
chr12_+_28410128 0.009 ENST00000381259.1
ENST00000381256.1
CCDC91

coiled-coil domain containing 91


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713)
0.2 0.5 GO:0071284 cellular response to lead ion(GO:0071284)
0.1 1.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.4 GO:2001295 malonyl-CoA biosynthetic process(GO:2001295)
0.0 0.4 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 2.6 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.5 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.2 GO:0002414 immunoglobulin transcytosis in epithelial cells(GO:0002414)
0.0 0.1 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.1 GO:2000645 negative regulation of receptor catabolic process(GO:2000645)
0.0 0.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0030327 prenylated protein catabolic process(GO:0030327)
0.0 0.7 GO:0035082 axoneme assembly(GO:0035082)
0.0 0.5 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.6 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.2 GO:0042670 photoreceptor cell outer segment organization(GO:0035845) retinal cone cell differentiation(GO:0042670) retinal cone cell development(GO:0046549)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 1.7 GO:0007368 determination of left/right symmetry(GO:0007368)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.7 GO:0002177 manchette(GO:0002177)
0.0 0.5 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 2.6 GO:0005796 Golgi lumen(GO:0005796)
0.0 1.6 GO:0000792 heterochromatin(GO:0000792)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.7 GO:0061714 folic acid receptor activity(GO:0061714)
0.2 0.5 GO:0032767 copper-dependent protein binding(GO:0032767)
0.1 0.4 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.6 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.2 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.0 0.1 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.6 REACTOME_TERMINATION_OF_O_GLYCAN_BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.4 REACTOME_DEGRADATION_OF_THE_EXTRACELLULAR_MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME_ACTIVATED_AMPK_STIMULATES_FATTY_ACID_OXIDATION_IN_MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle