Motif ID: HOXD10

Z-value: 0.942


Transcription factors associated with HOXD10:

Gene SymbolEntrez IDGene Name
HOXD10 ENSG00000128710.5 HOXD10

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HOXD10hg19_v2_chr2_+_176981307_176981307-0.155.0e-01Click!


Activity profile for motif HOXD10.

activity profile for motif HOXD10


Sorted Z-values histogram for motif HOXD10

Sorted Z-values for motif HOXD10



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXD10

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_68749745 2.039 ENST00000283916.6
TMPRSS11D
transmembrane protease, serine 11D
chr5_+_96211643 1.991 ENST00000437043.3
ENST00000510373.1
ERAP2

endoplasmic reticulum aminopeptidase 2

chr4_-_68749699 1.788 ENST00000545541.1
TMPRSS11D
transmembrane protease, serine 11D
chr1_+_152975488 1.758 ENST00000542696.1
SPRR3
small proline-rich protein 3
chr1_-_153113927 1.673 ENST00000368752.4
SPRR2B
small proline-rich protein 2B
chr18_+_29027696 1.437 ENST00000257189.4
DSG3
desmoglein 3
chr10_-_28623368 1.250 ENST00000441595.2
MPP7
membrane protein, palmitoylated 7 (MAGUK p55 subfamily member 7)
chr8_+_39770803 1.220 ENST00000518237.1
IDO1
indoleamine 2,3-dioxygenase 1
chr2_-_214016314 1.162 ENST00000434687.1
ENST00000374319.4
IKZF2

IKAROS family zinc finger 2 (Helios)

chr17_-_38938786 1.126 ENST00000301656.3
KRT27
keratin 27
chr4_-_47983519 1.083 ENST00000358519.4
ENST00000544810.1
ENST00000402813.3
CNGA1


cyclic nucleotide gated channel alpha 1


chr1_+_62439037 0.999 ENST00000545929.1
INADL
InaD-like (Drosophila)
chr13_+_78109884 0.982 ENST00000377246.3
ENST00000349847.3
SCEL

sciellin

chr7_+_132333553 0.974 ENST00000332558.4
AC009365.3
AC009365.3
chr13_+_78109804 0.954 ENST00000535157.1
SCEL
sciellin
chr9_-_21142144 0.931 ENST00000380229.2
IFNW1
interferon, omega 1
chr15_+_41549105 0.892 ENST00000560965.1
CHP1
calcineurin-like EF-hand protein 1
chr2_+_90458201 0.875 ENST00000603238.1
CH17-132F21.1
Uncharacterized protein
chr2_-_161056762 0.868 ENST00000428609.2
ENST00000409967.2
ITGB6

integrin, beta 6

chr4_+_71063641 0.813 ENST00000514097.1
ODAM
odontogenic, ameloblast asssociated
chr7_-_111032971 0.760 ENST00000450877.1
IMMP2L
IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr2_-_190044480 0.757 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr11_-_19082216 0.752 ENST00000329773.2
MRGPRX2
MAS-related GPR, member X2
chr19_-_51456321 0.743 ENST00000391809.2
KLK5
kallikrein-related peptidase 5
chr7_+_76054224 0.734 ENST00000394857.3
ZP3
zona pellucida glycoprotein 3 (sperm receptor)
chr2_+_135011731 0.732 ENST00000281923.2
MGAT5
mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase
chr18_+_61445007 0.727 ENST00000447428.1
ENST00000546027.1
SERPINB7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

chr12_+_8309630 0.695 ENST00000396570.3
ZNF705A
zinc finger protein 705A
chr9_+_75263565 0.690 ENST00000396237.3
TMC1
transmembrane channel-like 1
chr6_+_37897735 0.683 ENST00000373389.5
ZFAND3
zinc finger, AN1-type domain 3
chr12_-_91576561 0.675 ENST00000547568.2
ENST00000552962.1
DCN

decorin

chr12_-_13248598 0.645 ENST00000337630.6
ENST00000545699.1
GSG1

germ cell associated 1

chr4_+_187148556 0.640 ENST00000264690.6
ENST00000446598.2
ENST00000414291.1
ENST00000513864.1
KLKB1



kallikrein B, plasma (Fletcher factor) 1



chr12_-_25055177 0.640 ENST00000538118.1
BCAT1
branched chain amino-acid transaminase 1, cytosolic
chr4_+_40198527 0.637 ENST00000381799.5
RHOH
ras homolog family member H
chr14_+_67291158 0.624 ENST00000555456.1
GPHN
gephyrin
chr6_+_42018614 0.620 ENST00000465926.1
ENST00000482432.1
TAF8

TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 43kDa

chr3_+_169629354 0.614 ENST00000428432.2
ENST00000335556.3
SAMD7

sterile alpha motif domain containing 7

chr2_-_161056802 0.612 ENST00000283249.2
ENST00000409872.1
ITGB6

integrin, beta 6

chr22_-_50524298 0.612 ENST00000311597.5
MLC1
megalencephalic leukoencephalopathy with subcortical cysts 1
chr12_-_48164812 0.606 ENST00000549151.1
ENST00000548919.1
RAPGEF3

Rap guanine nucleotide exchange factor (GEF) 3

chr12_-_92536433 0.592 ENST00000551563.2
ENST00000546975.1
ENST00000549802.1
C12orf79


chromosome 12 open reading frame 79


chr2_+_196313239 0.576 ENST00000413290.1
AC064834.1
AC064834.1
chr13_-_47012325 0.568 ENST00000409879.2
KIAA0226L
KIAA0226-like
chr6_-_130543958 0.563 ENST00000437477.2
ENST00000439090.2
SAMD3

sterile alpha motif domain containing 3

chr3_+_57882024 0.556 ENST00000494088.1
SLMAP
sarcolemma associated protein
chr12_+_21525818 0.555 ENST00000240652.3
ENST00000542023.1
ENST00000537593.1
IAPP


islet amyloid polypeptide


chr4_-_76944621 0.553 ENST00000306602.1
CXCL10
chemokine (C-X-C motif) ligand 10
chr6_+_147527103 0.542 ENST00000179882.6
STXBP5
syntaxin binding protein 5 (tomosyn)
chr20_+_59654146 0.533 ENST00000441660.1
RP5-827L5.1
RP5-827L5.1
chr12_-_12674032 0.530 ENST00000298573.4
DUSP16
dual specificity phosphatase 16
chr11_+_133938820 0.527 ENST00000299106.4
ENST00000529443.2
JAM3

junctional adhesion molecule 3

chr2_-_165698662 0.524 ENST00000194871.6
ENST00000445474.2
COBLL1

cordon-bleu WH2 repeat protein-like 1

chrX_+_15808569 0.521 ENST00000380308.3
ENST00000307771.7
ZRSR2

zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2

chr3_+_186435137 0.520 ENST00000447445.1
KNG1
kininogen 1
chr6_+_20534672 0.517 ENST00000274695.4
ENST00000378624.4
CDKAL1

CDK5 regulatory subunit associated protein 1-like 1

chr2_-_211341411 0.514 ENST00000233714.4
ENST00000443314.1
ENST00000441020.3
ENST00000450366.2
ENST00000431941.2
LANCL1




LanC lantibiotic synthetase component C-like 1 (bacterial)




chr6_+_166945369 0.510 ENST00000598601.1
Z98049.1
CDNA FLJ25492 fis, clone CBR01389; Uncharacterized protein
chr9_+_75229616 0.503 ENST00000340019.3
TMC1
transmembrane channel-like 1
chr2_+_101437487 0.502 ENST00000427413.1
ENST00000542504.1
NPAS2

neuronal PAS domain protein 2

chr8_-_131399110 0.502 ENST00000521426.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr16_-_20681177 0.494 ENST00000524149.1
ACSM1
acyl-CoA synthetase medium-chain family member 1
chr15_-_55562479 0.491 ENST00000564609.1
RAB27A
RAB27A, member RAS oncogene family
chr10_+_98064085 0.481 ENST00000419175.1
ENST00000371174.2
DNTT

DNA nucleotidylexotransferase

chr9_-_74675521 0.467 ENST00000377024.3
C9orf57
chromosome 9 open reading frame 57
chr18_+_48918368 0.464 ENST00000583982.1
ENST00000578152.1
ENST00000583609.1
ENST00000435144.1
ENST00000580841.1
RP11-267C16.1




RP11-267C16.1




chr17_-_2966901 0.460 ENST00000575751.1
OR1D5
olfactory receptor, family 1, subfamily D, member 5
chr6_-_29324054 0.458 ENST00000543825.1
OR5V1
olfactory receptor, family 5, subfamily V, member 1
chr1_+_192127578 0.450 ENST00000367460.3
RGS18
regulator of G-protein signaling 18
chr14_+_22615942 0.441 ENST00000390457.2
TRAV27
T cell receptor alpha variable 27
chr7_-_108168580 0.440 ENST00000453085.1
PNPLA8
patatin-like phospholipase domain containing 8
chr5_-_135290705 0.428 ENST00000274507.1
LECT2
leukocyte cell-derived chemotaxin 2
chr6_-_137494775 0.428 ENST00000349184.4
ENST00000296980.2
ENST00000339602.3
IL22RA2


interleukin 22 receptor, alpha 2


chr2_+_68961934 0.426 ENST00000409202.3
ARHGAP25
Rho GTPase activating protein 25
chr7_+_132937820 0.425 ENST00000393161.2
ENST00000253861.4
EXOC4

exocyst complex component 4

chr5_-_39203093 0.420 ENST00000515010.1
FYB
FYN binding protein
chr3_-_128206759 0.417 ENST00000430265.2
GATA2
GATA binding protein 2
chr6_+_121756809 0.415 ENST00000282561.3
GJA1
gap junction protein, alpha 1, 43kDa
chr2_-_29297127 0.411 ENST00000331664.5
C2orf71
chromosome 2 open reading frame 71
chr18_+_23713808 0.405 ENST00000415576.2
ENST00000343848.6
ENST00000308268.6
PSMA8


proteasome (prosome, macropain) subunit, alpha type, 8


chr5_+_140227357 0.404 ENST00000378122.3
PCDHA9
protocadherin alpha 9
chr2_+_68961905 0.403 ENST00000295381.3
ARHGAP25
Rho GTPase activating protein 25
chr4_-_70080449 0.401 ENST00000446444.1
UGT2B11
UDP glucuronosyltransferase 2 family, polypeptide B11
chr3_-_195310802 0.400 ENST00000421243.1
ENST00000453131.1
APOD

apolipoprotein D

chr8_+_62200509 0.394 ENST00000519846.1
ENST00000518592.1
ENST00000325897.4
CLVS1


clavesin 1


chr1_+_74701062 0.394 ENST00000326637.3
TNNI3K
TNNI3 interacting kinase
chr3_-_37216055 0.393 ENST00000336686.4
LRRFIP2
leucine rich repeat (in FLII) interacting protein 2
chr14_+_72399114 0.385 ENST00000553525.1
ENST00000555571.1
RGS6

regulator of G-protein signaling 6

chr11_-_64647144 0.382 ENST00000359393.2
ENST00000433803.1
ENST00000411683.1
EHD1


EH-domain containing 1


chr12_-_10324716 0.382 ENST00000545927.1
ENST00000432556.2
ENST00000309539.3
ENST00000544577.1
OLR1



oxidized low density lipoprotein (lectin-like) receptor 1



chr2_+_90211643 0.382 ENST00000390277.2
IGKV3D-11
immunoglobulin kappa variable 3D-11
chr14_+_51955831 0.381 ENST00000356218.4
FRMD6
FERM domain containing 6
chr6_-_25830785 0.379 ENST00000468082.1
SLC17A1
solute carrier family 17 (organic anion transporter), member 1
chr8_-_101719159 0.374 ENST00000520868.1
ENST00000522658.1
PABPC1

poly(A) binding protein, cytoplasmic 1

chr13_+_114567131 0.368 ENST00000608651.1
GAS6-AS2
GAS6 antisense RNA 2 (head to head)
chr3_+_140981456 0.366 ENST00000504264.1
ACPL2
acid phosphatase-like 2
chr10_+_96443378 0.362 ENST00000285979.6
CYP2C18
cytochrome P450, family 2, subfamily C, polypeptide 18
chr7_-_107443652 0.360 ENST00000340010.5
ENST00000422236.2
ENST00000453332.1
SLC26A3


solute carrier family 26 (anion exchanger), member 3


chr7_+_134551583 0.358 ENST00000435928.1
CALD1
caldesmon 1
chr8_+_7801144 0.358 ENST00000443676.1
ZNF705B
zinc finger protein 705B
chr6_-_150067696 0.357 ENST00000340413.2
ENST00000367403.3
NUP43

nucleoporin 43kDa

chr9_+_82187487 0.355 ENST00000435650.1
ENST00000414465.1
ENST00000376537.4
ENST00000376534.4
TLE4



transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)



chrX_-_41449204 0.355 ENST00000378179.3
CASK
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr17_-_38911580 0.352 ENST00000312150.4
KRT25
keratin 25
chr13_+_30510003 0.347 ENST00000400540.1
LINC00544
long intergenic non-protein coding RNA 544
chr4_+_118955500 0.346 ENST00000296499.5
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr2_+_102456277 0.344 ENST00000421882.1
MAP4K4
mitogen-activated protein kinase kinase kinase kinase 4
chr3_-_27498235 0.341 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7


solute carrier family 4, sodium bicarbonate cotransporter, member 7


chr10_+_11047259 0.338 ENST00000379261.4
ENST00000416382.2
CELF2

CUGBP, Elav-like family member 2

chr22_-_29107919 0.338 ENST00000434810.1
ENST00000456369.1
CHEK2

checkpoint kinase 2

chr9_+_82187630 0.334 ENST00000265284.6
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr11_-_130786333 0.330 ENST00000533214.1
ENST00000528555.1
ENST00000530356.1
ENST00000539184.1
SNX19



sorting nexin 19



chr2_-_86333244 0.329 ENST00000263857.6
ENST00000409681.1
POLR1A

polymerase (RNA) I polypeptide A, 194kDa

chr3_+_136676707 0.328 ENST00000329582.4
IL20RB
interleukin 20 receptor beta
chr12_-_91546926 0.326 ENST00000550758.1
DCN
decorin
chrX_-_49965663 0.324 ENST00000376056.2
ENST00000376058.2
ENST00000358526.2
AKAP4


A kinase (PRKA) anchor protein 4


chr3_-_99569821 0.324 ENST00000487087.1
FILIP1L
filamin A interacting protein 1-like
chr6_+_27791862 0.319 ENST00000355057.1
HIST1H4J
histone cluster 1, H4j
chrX_+_37639302 0.319 ENST00000545017.1
ENST00000536160.1
CYBB

cytochrome b-245, beta polypeptide

chr2_+_115199876 0.317 ENST00000436732.1
ENST00000410059.1
DPP10

dipeptidyl-peptidase 10 (non-functional)

chr4_-_76928641 0.315 ENST00000264888.5
CXCL9
chemokine (C-X-C motif) ligand 9
chr7_+_106505912 0.315 ENST00000359195.3
PIK3CG
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma
chr4_+_166300084 0.315 ENST00000402744.4
CPE
carboxypeptidase E
chr12_-_3862245 0.310 ENST00000252322.1
ENST00000440314.2
EFCAB4B

EF-hand calcium binding domain 4B

chr1_-_242612779 0.308 ENST00000427495.1
PLD5
phospholipase D family, member 5
chr1_-_155942086 0.307 ENST00000368315.4
ARHGEF2
Rho/Rac guanine nucleotide exchange factor (GEF) 2
chr3_+_30647994 0.305 ENST00000295754.5
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr14_+_22265444 0.303 ENST00000390430.2
TRAV8-1
T cell receptor alpha variable 8-1
chr3_+_30648066 0.302 ENST00000359013.4
TGFBR2
transforming growth factor, beta receptor II (70/80kDa)
chr3_+_57881966 0.301 ENST00000495364.1
SLMAP
sarcolemma associated protein
chr2_+_210444748 0.300 ENST00000392194.1
MAP2
microtubule-associated protein 2
chr16_-_79015739 0.296 ENST00000594986.1
PIH1
HCG1979943; Uncharacterized protein
chr17_+_15604513 0.296 ENST00000481540.1
ZNF286A
Homo sapiens zinc finger protein 286A (ZNF286A), transcript variant 6, mRNA.
chr2_+_90273679 0.290 ENST00000423080.2
IGKV3D-7
immunoglobulin kappa variable 3D-7
chr2_-_90538397 0.281 ENST00000443397.3
RP11-685N3.1
Uncharacterized protein
chr7_+_107224364 0.280 ENST00000491150.1
BCAP29
B-cell receptor-associated protein 29
chr9_-_116163400 0.277 ENST00000277315.5
ENST00000448137.1
ENST00000409155.3
ALAD


aminolevulinate dehydratase


chrX_+_37639264 0.276 ENST00000378588.4
CYBB
cytochrome b-245, beta polypeptide
chr11_+_120973375 0.274 ENST00000264037.2
TECTA
tectorin alpha
chr12_-_118797475 0.271 ENST00000541786.1
ENST00000419821.2
ENST00000541878.1
TAOK3


TAO kinase 3


chr19_-_53770972 0.269 ENST00000311170.4
VN1R4
vomeronasal 1 receptor 4
chr10_+_120967072 0.265 ENST00000392870.2
GRK5
G protein-coupled receptor kinase 5
chr17_-_10276319 0.264 ENST00000252172.4
ENST00000418404.3
MYH13

myosin, heavy chain 13, skeletal muscle

chr11_-_104827425 0.261 ENST00000393150.3
CASP4
caspase 4, apoptosis-related cysteine peptidase
chr1_+_62417957 0.260 ENST00000307297.7
ENST00000543708.1
INADL

InaD-like (Drosophila)

chr9_+_125376948 0.259 ENST00000297913.2
OR1Q1
olfactory receptor, family 1, subfamily Q, member 1
chr3_-_120461353 0.258 ENST00000483733.1
RABL3
RAB, member of RAS oncogene family-like 3
chr1_-_95391315 0.257 ENST00000545882.1
ENST00000415017.1
CNN3

calponin 3, acidic

chr15_+_71389281 0.256 ENST00000355327.3
THSD4
thrombospondin, type I, domain containing 4
chr6_-_135375986 0.254 ENST00000525067.1
ENST00000367822.5
ENST00000367837.5
HBS1L


HBS1-like (S. cerevisiae)


chr2_-_209010874 0.253 ENST00000260988.4
CRYGB
crystallin, gamma B
chr11_+_55594695 0.253 ENST00000378397.1
OR5L2
olfactory receptor, family 5, subfamily L, member 2
chr2_+_157330081 0.252 ENST00000409674.1
GPD2
glycerol-3-phosphate dehydrogenase 2 (mitochondrial)
chr2_-_165424973 0.250 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr5_-_64064508 0.249 ENST00000513458.4
SREK1IP1
SREK1-interacting protein 1
chr9_+_34329493 0.249 ENST00000379158.2
ENST00000346365.4
ENST00000379155.5
NUDT2


nudix (nucleoside diphosphate linked moiety X)-type motif 2


chr2_+_87565634 0.247 ENST00000421835.2
IGKV3OR2-268
immunoglobulin kappa variable 3/OR2-268 (non-functional)
chr5_-_27038683 0.246 ENST00000511822.1
ENST00000231021.4
CDH9

cadherin 9, type 2 (T1-cadherin)

chr2_-_203735484 0.245 ENST00000420558.1
ENST00000418208.1
ICA1L

islet cell autoantigen 1,69kDa-like

chr16_-_15180257 0.245 ENST00000540462.1
RRN3
RRN3 RNA polymerase I transcription factor homolog (S. cerevisiae)
chr13_+_76378305 0.245 ENST00000526371.1
ENST00000526528.1
LMO7

LIM domain 7

chr1_-_232598163 0.244 ENST00000308942.4
SIPA1L2
signal-induced proliferation-associated 1 like 2
chr15_+_69373184 0.243 ENST00000558147.1
ENST00000440444.1
LINC00277

long intergenic non-protein coding RNA 277

chr11_+_18433840 0.241 ENST00000541669.1
ENST00000280704.4
LDHC

lactate dehydrogenase C

chrX_+_12924732 0.241 ENST00000218032.6
ENST00000311912.5
TLR8

toll-like receptor 8

chr16_-_30122717 0.240 ENST00000566613.1
GDPD3
glycerophosphodiester phosphodiesterase domain containing 3
chr2_-_99870744 0.236 ENST00000409238.1
ENST00000423800.1
LYG2

lysozyme G-like 2

chr17_-_21454898 0.236 ENST00000391411.5
ENST00000412778.3
C17orf51

chromosome 17 open reading frame 51

chr2_+_11679963 0.236 ENST00000263834.5
GREB1
growth regulation by estrogen in breast cancer 1
chr21_-_27423339 0.235 ENST00000415997.1
APP
amyloid beta (A4) precursor protein
chr10_+_116697946 0.235 ENST00000298746.3
TRUB1
TruB pseudouridine (psi) synthase family member 1
chr12_+_48876275 0.234 ENST00000314014.2
C12orf54
chromosome 12 open reading frame 54
chr9_+_4839762 0.234 ENST00000448872.2
ENST00000441844.1
RCL1

RNA terminal phosphate cyclase-like 1

chr7_+_135611542 0.233 ENST00000416501.1
AC015987.2
AC015987.2
chr8_+_42873548 0.232 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr9_+_82188077 0.229 ENST00000425506.1
TLE4
transducin-like enhancer of split 4 (E(sp1) homolog, Drosophila)
chr5_+_39105358 0.229 ENST00000593965.1
AC008964.1
AC008964.1
chr6_-_150067632 0.227 ENST00000460354.2
ENST00000367404.4
ENST00000543637.1
NUP43


nucleoporin 43kDa


chr9_-_4666421 0.223 ENST00000381895.5
SPATA6L
spermatogenesis associated 6-like
chr12_-_118796910 0.220 ENST00000541186.1
ENST00000539872.1
TAOK3

TAO kinase 3

chr1_-_229569834 0.220 ENST00000366684.3
ENST00000366683.2
ACTA1

actin, alpha 1, skeletal muscle

chr7_+_112262421 0.218 ENST00000453459.1
AC002463.3
AC002463.3
chr2_-_89521942 0.218 ENST00000482769.1
IGKV2-28
immunoglobulin kappa variable 2-28
chr15_+_26360970 0.216 ENST00000556159.1
ENST00000557523.1
LINC00929

long intergenic non-protein coding RNA 929

chr3_+_130569592 0.214 ENST00000533801.2
ATP2C1
ATPase, Ca++ transporting, type 2C, member 1
chr5_-_77590480 0.213 ENST00000519295.1
ENST00000255194.6
AP3B1

adaptor-related protein complex 3, beta 1 subunit

chr18_+_616672 0.212 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr12_+_18891045 0.212 ENST00000317658.3
CAPZA3
capping protein (actin filament) muscle Z-line, alpha 3
chr18_+_55816546 0.211 ENST00000435432.2
ENST00000357895.5
ENST00000586263.1
NEDD4L


neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase


chr4_+_76481258 0.210 ENST00000311623.4
ENST00000435974.2
C4orf26

chromosome 4 open reading frame 26

chrX_-_8139308 0.208 ENST00000317103.4
VCX2
variable charge, X-linked 2
chr4_-_153332886 0.208 ENST00000603841.1
FBXW7
F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
chr12_-_10022735 0.207 ENST00000228438.2
CLEC2B
C-type lectin domain family 2, member B
chr13_+_32313658 0.207 ENST00000380314.1
ENST00000298386.2
RXFP2

relaxin/insulin-like family peptide receptor 2

chr12_-_76817036 0.205 ENST00000546946.1
OSBPL8
oxysterol binding protein-like 8
chr4_-_123377880 0.205 ENST00000226730.4
IL2
interleukin 2
chr3_+_186435065 0.204 ENST00000287611.2
ENST00000265023.4
KNG1

kininogen 1

chr1_+_117963209 0.202 ENST00000449370.2
MAN1A2
mannosidase, alpha, class 1A, member 2
chr8_+_21823726 0.200 ENST00000433566.4
XPO7
exportin 7
chr22_+_29469012 0.197 ENST00000400335.4
ENST00000400338.2
KREMEN1

kringle containing transmembrane protein 1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0036269 swimming behavior(GO:0036269)
0.3 0.8 GO:0061300 cerebellum vasculature development(GO:0061300)
0.3 0.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.7 GO:2000196 positive regulation of female gonad development(GO:2000196)
0.2 0.6 GO:0002541 activation of plasma proteins involved in acute inflammatory response(GO:0002541)
0.2 0.6 GO:0072579 molybdenum incorporation into molybdenum-molybdopterin complex(GO:0018315) metal incorporation into metallo-molybdopterin complex(GO:0042040) glycine receptor clustering(GO:0072579)
0.2 0.6 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.2 1.2 GO:0060005 vestibular reflex(GO:0060005)
0.2 0.7 GO:0090362 positive regulation of platelet-derived growth factor production(GO:0090362)
0.2 0.5 GO:0018874 benzoate metabolic process(GO:0018874)
0.2 0.6 GO:0033123 positive regulation of cyclic nucleotide catabolic process(GO:0030807) positive regulation of cAMP catabolic process(GO:0030822) positive regulation of purine nucleotide catabolic process(GO:0033123)
0.1 0.4 GO:0046338 phosphatidylethanolamine catabolic process(GO:0046338)
0.1 2.0 GO:0019885 antigen processing and presentation of endogenous peptide antigen via MHC class I(GO:0019885)
0.1 1.3 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.4 GO:0010725 regulation of primitive erythrocyte differentiation(GO:0010725) eosinophil fate commitment(GO:0035854)
0.1 0.4 GO:0010652 regulation of cell communication by chemical coupling(GO:0010645) positive regulation of cell communication by chemical coupling(GO:0010652)
0.1 0.8 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 1.5 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 0.4 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.7 GO:0002803 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) positive regulation of antibacterial peptide production(GO:0002803)
0.1 0.9 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 0.2 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.6 GO:1904844 response to L-glutamine(GO:1904844) cellular response to L-glutamine(GO:1904845)
0.1 0.3 GO:1903926 signal transduction involved in intra-S DNA damage checkpoint(GO:0072428) response to bisphenol A(GO:1903925) cellular response to bisphenol A(GO:1903926)
0.1 0.9 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417) negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.1 0.6 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.1 0.5 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.1 GO:0052047 interaction with other organism via secreted substance involved in symbiotic interaction(GO:0052047)
0.1 0.3 GO:1905205 positive regulation of connective tissue replacement(GO:1905205)
0.1 0.3 GO:0071284 response to platinum ion(GO:0070541) cellular response to lead ion(GO:0071284)
0.1 0.9 GO:0043950 positive regulation of cAMP-mediated signaling(GO:0043950)
0.1 0.5 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.3 GO:0001808 negative regulation of type IV hypersensitivity(GO:0001808)
0.1 0.5 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.1 0.3 GO:1990502 dense core granule maturation(GO:1990502)
0.1 0.2 GO:0051138 positive regulation of NK T cell differentiation(GO:0051138)
0.1 0.1 GO:0030805 regulation of cyclic nucleotide catabolic process(GO:0030805) regulation of cAMP catabolic process(GO:0030820) regulation of purine nucleotide catabolic process(GO:0033121)
0.1 1.0 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 1.0 GO:0047484 regulation of response to osmotic stress(GO:0047484)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 0.6 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 3.6 GO:0018149 peptide cross-linking(GO:0018149)
0.1 0.2 GO:0021526 medial motor column neuron differentiation(GO:0021526)
0.1 0.5 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.3 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.1 0.4 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 0.4 GO:0003383 apical constriction(GO:0003383)
0.1 0.3 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897) secretory granule localization(GO:0032252)
0.1 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.3 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.3 GO:0032468 Golgi calcium ion homeostasis(GO:0032468)
0.0 0.2 GO:0071874 cellular response to norepinephrine stimulus(GO:0071874)
0.0 1.0 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.3 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 4.0 GO:0007585 respiratory gaseous exchange(GO:0007585)
0.0 0.2 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.2 GO:2000639 regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639)
0.0 0.2 GO:0034599 cellular response to oxidative stress(GO:0034599)
0.0 0.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.4 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.0 0.2 GO:0019249 lactate biosynthetic process(GO:0019249)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233) regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.2 GO:0018243 protein O-linked glycosylation via threonine(GO:0018243)
0.0 0.4 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.3 GO:0019236 response to pheromone(GO:0019236)
0.0 0.1 GO:1900158 positive regulation of osteoclast proliferation(GO:0090290) negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.0 0.2 GO:0090131 mesenchyme migration(GO:0090131)
0.0 0.3 GO:0070309 lens fiber cell morphogenesis(GO:0070309)
0.0 0.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.4 GO:1903546 protein localization to photoreceptor outer segment(GO:1903546)
0.0 0.2 GO:0090238 positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.4 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.4 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 1.1 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.2 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:0001865 NK T cell differentiation(GO:0001865)
0.0 0.3 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.0 0.2 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.3 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 1.0 GO:0022400 regulation of rhodopsin mediated signaling pathway(GO:0022400)
0.0 0.1 GO:0006663 platelet activating factor biosynthetic process(GO:0006663)
0.0 0.5 GO:0051775 response to redox state(GO:0051775)
0.0 0.5 GO:0001780 neutrophil homeostasis(GO:0001780)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.1 GO:1903285 negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of dopamine uptake involved in synaptic transmission(GO:0051585) norepinephrine uptake(GO:0051620) regulation of norepinephrine uptake(GO:0051621) negative regulation of norepinephrine uptake(GO:0051622) negative regulation of catecholamine uptake involved in synaptic transmission(GO:0051945) regulation of glutathione peroxidase activity(GO:1903282) positive regulation of glutathione peroxidase activity(GO:1903284) positive regulation of hydrogen peroxide catabolic process(GO:1903285) positive regulation of peroxidase activity(GO:2000470)
0.0 0.2 GO:1901374 acetate ester transport(GO:1901374)
0.0 0.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.4 GO:0086069 bundle of His cell to Purkinje myocyte communication(GO:0086069)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.2 GO:0034454 microtubule anchoring at centrosome(GO:0034454)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 1.0 GO:1904837 beta-catenin-TCF complex assembly(GO:1904837)
0.0 0.2 GO:0019530 taurine metabolic process(GO:0019530)
0.0 0.5 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.0 0.3 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.7 GO:0042311 vasodilation(GO:0042311)
0.0 1.4 GO:0045576 mast cell activation(GO:0045576)
0.0 1.4 GO:0070268 cornification(GO:0070268)
0.0 0.3 GO:1904646 cellular response to beta-amyloid(GO:1904646)
0.0 0.0 GO:0006711 estrogen catabolic process(GO:0006711)
0.0 0.2 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.2 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.3 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 2.1 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.3 GO:0060117 auditory receptor cell development(GO:0060117)
0.0 0.3 GO:0032780 negative regulation of ATPase activity(GO:0032780)
0.0 0.1 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.0 0.0 GO:0060620 regulation of cholesterol import(GO:0060620) regulation of sterol import(GO:2000909)
0.0 0.1 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.0 0.0 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.0 0.1 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.0 GO:0044501 modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.0 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.0 0.9 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.0 0.3 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.2 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.3 0.8 GO:0005588 collagen type V trimer(GO:0005588)
0.2 1.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 0.7 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 7.0 GO:0001533 cornified envelope(GO:0001533)
0.1 1.4 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.7 GO:0097209 epidermal lamellar body(GO:0097209)
0.1 0.7 GO:0089701 U2AF(GO:0089701)
0.1 1.2 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.3 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.4 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 0.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.0 GO:0005589 collagen type VI trimer(GO:0005589) collagen beaded filament(GO:0098647)
0.1 0.6 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.1 1.1 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.0 0.4 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.4 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0043291 RAVE complex(GO:0043291)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:1990761 growth cone lamellipodium(GO:1990761) growth cone filopodium(GO:1990812)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.0 0.8 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.9 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.2 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.2 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.3 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.6 GO:0001772 immunological synapse(GO:0001772)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.8 GO:0002102 podosome(GO:0002102)
0.0 0.1 GO:0005826 actomyosin contractile ring(GO:0005826)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0036020 endolysosome membrane(GO:0036020)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0033754 indoleamine 2,3-dioxygenase activity(GO:0033754)
0.2 0.6 GO:0061599 molybdopterin adenylyltransferase activity(GO:0061598) molybdopterin molybdotransferase activity(GO:0061599)
0.2 0.9 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 0.6 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 0.7 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.6 GO:0052654 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.3 GO:0016503 pheromone receptor activity(GO:0016503)
0.1 0.3 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.1 2.0 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.1 1.1 GO:0043855 intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855)
0.1 0.2 GO:0001181 transcription factor activity, core RNA polymerase I binding(GO:0001181)
0.1 0.7 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.1 0.7 GO:0032190 manganese ion transmembrane transporter activity(GO:0005384) acrosin binding(GO:0032190)
0.1 0.3 GO:0052590 sn-glycerol-3-phosphate:ubiquinone oxidoreductase activity(GO:0052590) sn-glycerol-3-phosphate:ubiquinone-8 oxidoreductase activity(GO:0052591)
0.1 0.2 GO:0080130 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 1.0 GO:0005132 type I interferon receptor binding(GO:0005132)
0.1 0.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.4 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075)
0.1 0.2 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.1 0.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.5 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0008513 acetylcholine transmembrane transporter activity(GO:0005277) secondary active organic cation transmembrane transporter activity(GO:0008513) acetate ester transmembrane transporter activity(GO:1901375)
0.0 0.1 GO:0017130 poly(C) RNA binding(GO:0017130)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 1.0 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.3 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.4 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.4 GO:0031013 troponin I binding(GO:0031013)
0.0 0.1 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.5 GO:0022833 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.5 GO:0043295 glutathione binding(GO:0043295)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134) glycosphingolipid binding(GO:0043208)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.6 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.1 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 0.7 GO:0031489 myosin V binding(GO:0031489)
0.0 0.2 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.1 GO:0060961 phospholipase D inhibitor activity(GO:0060961)
0.0 0.3 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0005477 pyruvate secondary active transmembrane transporter activity(GO:0005477)
0.0 0.2 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 5.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.4 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.4 GO:0070330 aromatase activity(GO:0070330)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.4 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 1.3 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 0.4 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.4 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 0.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.5 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.1 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0004321 fatty-acyl-CoA synthase activity(GO:0004321)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.7 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.0 GO:0005178 integrin binding(GO:0005178)
0.0 1.2 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID_INTEGRIN5_PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.1 PID_RHODOPSIN_PATHWAY Visual signal transduction: Rods
0.0 1.4 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.6 PID_ARF_3PATHWAY Arf1 pathway
0.0 0.4 PID_TCR_CALCIUM_PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 NABA_BASEMENT_MEMBRANES Genes encoding structural components of basement membranes
0.0 0.6 ST_G_ALPHA_S_PATHWAY G alpha s Pathway
0.0 0.5 PID_CIRCADIAN_PATHWAY Circadian rhythm pathway
0.0 0.9 PID_SYNDECAN_2_PATHWAY Syndecan-2-mediated signaling events
0.0 0.5 PID_P38_MKK3_6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID_AMB2_NEUTROPHILS_PATHWAY amb2 Integrin signaling
0.0 0.7 PID_P38_ALPHA_BETA_PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.8 PID_GLYPICAN_1PATHWAY Glypican 1 network
0.0 0.5 PID_DNA_PK_PATHWAY DNA-PK pathway in nonhomologous end joining
0.0 1.1 PID_NFAT_TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.8 PID_SYNDECAN_1_PATHWAY Syndecan-1-mediated signaling events
0.0 0.9 PID_CXCR3_PATHWAY CXCR3-mediated signaling events
0.0 0.2 PID_MYC_PATHWAY C-MYC pathway
0.0 0.2 PID_P38_GAMMA_DELTA_PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.3 PID_IL8_CXCR1_PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.7 PID_ARF6_TRAFFICKING_PATHWAY Arf6 trafficking events
0.0 0.4 PID_ALPHA_SYNUCLEIN_PATHWAY Alpha-synuclein signaling

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME_APOPTOTIC_CLEAVAGE_OF_CELL_ADHESION_PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.3 REACTOME_TRYPTOPHAN_CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.9 REACTOME_CS_DS_DEGRADATION Genes involved in CS/DS degradation
0.0 1.1 REACTOME_INSULIN_SYNTHESIS_AND_PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.7 REACTOME_N_GLYCAN_ANTENNAE_ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.5 REACTOME_INTRINSIC_PATHWAY Genes involved in Intrinsic Pathway
0.0 0.7 REACTOME_ACYL_CHAIN_REMODELLING_OF_PC Genes involved in Acyl chain remodelling of PC
0.0 0.3 REACTOME_NOREPINEPHRINE_NEUROTRANSMITTER_RELEASE_CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.0 0.6 REACTOME_TGF_BETA_RECEPTOR_SIGNALING_IN_EMT_EPITHELIAL_TO_MESENCHYMAL_TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.4 REACTOME_GAP_JUNCTION_DEGRADATION Genes involved in Gap junction degradation
0.0 0.6 REACTOME_BRANCHED_CHAIN_AMINO_ACID_CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.9 REACTOME_TIGHT_JUNCTION_INTERACTIONS Genes involved in Tight junction interactions
0.0 2.0 REACTOME_AMYLOIDS Genes involved in Amyloids
0.0 0.5 REACTOME_GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME_SIGNAL_REGULATORY_PROTEIN_SIRP_FAMILY_INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 1.2 REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME_TRAFFICKING_AND_PROCESSING_OF_ENDOSOMAL_TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 2.5 REACTOME_INTEGRIN_CELL_SURFACE_INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.5 REACTOME_CIRCADIAN_REPRESSION_OF_EXPRESSION_BY_REV_ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME_G2_M_DNA_DAMAGE_CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.6 REACTOME_RNA_POL_I_TRANSCRIPTION_INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.6 REACTOME_LATENT_INFECTION_OF_HOMO_SAPIENS_WITH_MYCOBACTERIUM_TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.7 REACTOME_NCAM1_INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME_METABOLISM_OF_PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME_BETA_DEFENSINS Genes involved in Beta defensins
0.0 0.2 REACTOME_DSCAM_INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME_XENOBIOTICS Genes involved in Xenobiotics
0.0 0.2 REACTOME_REGULATION_OF_APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.3 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA Genes involved in G beta:gamma signalling through PI3Kgamma