Motif ID: HSF4

Z-value: 0.559


Transcription factors associated with HSF4:

Gene SymbolEntrez IDGene Name
HSF4 ENSG00000102878.11 HSF4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
HSF4hg19_v2_chr16_+_67198683_671987150.262.2e-01Click!


Activity profile for motif HSF4.

activity profile for motif HSF4


Sorted Z-values histogram for motif HSF4

Sorted Z-values for motif HSF4



Network of associatons between targets according to the STRING database.



First level regulatory network of HSF4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_-_74137374 2.370 ENST00000322957.6
FOXJ1
forkhead box J1
chr18_-_71815051 2.007 ENST00000582526.1
ENST00000419743.2
FBXO15

F-box protein 15

chr18_-_71814999 2.000 ENST00000269500.5
FBXO15
F-box protein 15
chr19_-_55672037 1.852 ENST00000588076.1
DNAAF3
dynein, axonemal, assembly factor 3
chr1_-_60539405 1.472 ENST00000450089.2
C1orf87
chromosome 1 open reading frame 87
chr1_-_60539422 1.460 ENST00000371201.3
C1orf87
chromosome 1 open reading frame 87
chr2_-_238499303 1.125 ENST00000409576.1
RAB17
RAB17, member RAS oncogene family
chr1_-_173638976 1.099 ENST00000333279.2
ANKRD45
ankyrin repeat domain 45
chr5_+_140602904 0.900 ENST00000515856.2
ENST00000239449.4
PCDHB14

protocadherin beta 14

chr1_-_26633067 0.882 ENST00000421827.2
ENST00000374215.1
ENST00000374223.1
ENST00000357089.4
ENST00000535108.1
ENST00000314675.7
ENST00000436301.2
ENST00000423664.1
ENST00000374221.3
UBXN11








UBX domain protein 11








chr13_-_31736027 0.858 ENST00000380406.5
ENST00000320027.5
ENST00000380405.4
HSPH1


heat shock 105kDa/110kDa protein 1


chr5_-_13944652 0.817 ENST00000265104.4
DNAH5
dynein, axonemal, heavy chain 5
chr11_-_122932730 0.815 ENST00000532182.1
ENST00000524590.1
ENST00000528292.1
ENST00000533540.1
ENST00000525463.1
HSPA8




heat shock 70kDa protein 8




chr9_+_33025209 0.814 ENST00000330899.4
ENST00000544625.1
DNAJA1

DnaJ (Hsp40) homolog, subfamily A, member 1

chr19_-_6720686 0.797 ENST00000245907.6
C3
complement component 3
chr11_-_89956461 0.780 ENST00000320585.6
CHORDC1
cysteine and histidine-rich domain (CHORD) containing 1
chr13_-_31736132 0.777 ENST00000429785.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr11_-_122933043 0.761 ENST00000534624.1
ENST00000453788.2
ENST00000527387.1
HSPA8


heat shock 70kDa protein 8


chr11_-_89956227 0.761 ENST00000457199.2
ENST00000530765.1
CHORDC1

cysteine and histidine-rich domain (CHORD) containing 1

chr7_-_56119156 0.727 ENST00000421312.1
ENST00000416592.1
PSPH

phosphoserine phosphatase

chr20_+_18794370 0.717 ENST00000377428.2
SCP2D1
SCP2 sterol-binding domain containing 1
chr1_+_212782012 0.699 ENST00000341491.4
ENST00000366985.1
ATF3

activating transcription factor 3

chr7_-_56118981 0.688 ENST00000419984.2
ENST00000413218.1
ENST00000424596.1
PSPH


phosphoserine phosphatase


chr1_+_27248203 0.684 ENST00000321265.5
NUDC
nudC nuclear distribution protein
chr19_+_859654 0.629 ENST00000592860.1
CFD
complement factor D (adipsin)
chr10_-_62332357 0.622 ENST00000503366.1
ANK3
ankyrin 3, node of Ranvier (ankyrin G)
chr3_+_101443476 0.621 ENST00000327230.4
ENST00000494050.1
CEP97

centrosomal protein 97kDa

chr7_-_56119238 0.615 ENST00000275605.3
ENST00000395471.3
PSPH

phosphoserine phosphatase

chr9_+_74764278 0.596 ENST00000238018.4
ENST00000376989.3
GDA

guanine deaminase

chr16_-_18468926 0.581 ENST00000545114.1
RP11-1212A22.4
LOC339047 protein; Nuclear pore complex-interacting protein family member A3; Nuclear pore complex-interacting protein family member A5; Protein PKD1P1
chr11_-_108408895 0.574 ENST00000443411.1
ENST00000533052.1
EXPH5

exophilin 5

chr13_-_31736478 0.570 ENST00000445273.2
HSPH1
heat shock 105kDa/110kDa protein 1
chr19_-_51893827 0.563 ENST00000574814.1
CTD-2616J11.4
chromosome 19 open reading frame 84
chr2_-_238499131 0.555 ENST00000538644.1
RAB17
RAB17, member RAS oncogene family
chr10_+_131265443 0.542 ENST00000306010.7
MGMT
O-6-methylguanine-DNA methyltransferase
chr9_+_74764340 0.532 ENST00000376986.1
ENST00000358399.3
GDA

guanine deaminase

chr14_-_102553371 0.519 ENST00000553585.1
ENST00000216281.8
HSP90AA1

heat shock protein 90kDa alpha (cytosolic), class A member 1

chr4_+_76932326 0.495 ENST00000513353.1
ENST00000341029.5
ART3

ADP-ribosyltransferase 3

chr4_-_25865159 0.492 ENST00000502949.1
ENST00000264868.5
ENST00000513691.1
ENST00000514872.1
SEL1L3



sel-1 suppressor of lin-12-like 3 (C. elegans)



chr8_+_37594185 0.451 ENST00000518586.1
ENST00000335171.6
ENST00000521644.1
ERLIN2


ER lipid raft associated 2


chr19_+_6135646 0.438 ENST00000588304.1
ENST00000588485.1
ENST00000588722.1
ENST00000591403.1
ENST00000586696.1
ENST00000589401.1
ENST00000252669.5
ACSBG2






acyl-CoA synthetase bubblegum family member 2






chr15_+_41952591 0.411 ENST00000566718.1
ENST00000219905.7
ENST00000389936.4
ENST00000545763.1
MGA



MGA, MAX dimerization protein



chr14_-_61124977 0.395 ENST00000554986.1
SIX1
SIX homeobox 1
chr19_+_859425 0.376 ENST00000327726.6
CFD
complement factor D (adipsin)
chr17_+_33474826 0.366 ENST00000268876.5
ENST00000433649.1
ENST00000378449.1
UNC45B


unc-45 homolog B (C. elegans)


chr17_+_33474860 0.363 ENST00000394570.2
UNC45B
unc-45 homolog B (C. elegans)
chr2_-_69180012 0.355 ENST00000481498.1
GKN2
gastrokine 2
chr19_-_52133588 0.354 ENST00000570106.2
SIGLEC5
sialic acid binding Ig-like lectin 5
chr1_+_44679159 0.334 ENST00000315913.5
ENST00000372289.2
DMAP1

DNA methyltransferase 1 associated protein 1

chr2_+_85766280 0.334 ENST00000306434.3
MAT2A
methionine adenosyltransferase II, alpha
chr5_+_140501581 0.334 ENST00000194152.1
PCDHB4
protocadherin beta 4
chr11_+_112046190 0.328 ENST00000357685.5
ENST00000393032.2
ENST00000361053.4
BCO2


beta-carotene oxygenase 2


chr1_+_44679113 0.327 ENST00000361745.6
ENST00000446292.1
ENST00000440641.1
ENST00000436069.1
ENST00000437511.1
DMAP1




DNA methyltransferase 1 associated protein 1




chr5_-_140053152 0.327 ENST00000542735.1
DND1
DND microRNA-mediated repression inhibitor 1
chr5_-_70272055 0.319 ENST00000514857.2
NAIP
NLR family, apoptosis inhibitory protein
chr9_-_88715044 0.297 ENST00000388711.3
ENST00000466178.1
GOLM1

golgi membrane protein 1

chr16_-_28937027 0.293 ENST00000358201.4
RABEP2
rabaptin, RAB GTPase binding effector protein 2
chr5_-_10249990 0.293 ENST00000511437.1
ENST00000280330.8
ENST00000510047.1
FAM173B


family with sequence similarity 173, member B


chr18_+_9136758 0.291 ENST00000383440.2
ENST00000262126.4
ENST00000577992.1
ANKRD12


ankyrin repeat domain 12


chr7_-_100493744 0.290 ENST00000428317.1
ENST00000441605.1
ACHE

acetylcholinesterase (Yt blood group)

chr5_+_56469843 0.289 ENST00000514387.2
GPBP1
GC-rich promoter binding protein 1
chr9_-_88714421 0.277 ENST00000388712.3
GOLM1
golgi membrane protein 1
chr11_+_193065 0.271 ENST00000342878.2
SCGB1C1
secretoglobin, family 1C, member 1
chr21_+_44394620 0.269 ENST00000291547.5
PKNOX1
PBX/knotted 1 homeobox 1
chr16_+_14844670 0.263 ENST00000553201.1
NPIPA2
nuclear pore complex interacting protein family, member A2
chr8_-_27472198 0.255 ENST00000519472.1
ENST00000523589.1
ENST00000522413.1
ENST00000523396.1
ENST00000560366.1
CLU




clusterin




chr20_-_43589109 0.254 ENST00000372813.3
TOMM34
translocase of outer mitochondrial membrane 34
chr15_+_96869165 0.241 ENST00000421109.2
NR2F2
nuclear receptor subfamily 2, group F, member 2
chr2_-_69180083 0.236 ENST00000328895.4
GKN2
gastrokine 2
chr16_-_68034470 0.236 ENST00000412757.2
DPEP2
dipeptidase 2
chr18_-_19284724 0.234 ENST00000580981.1
ENST00000289119.2
ABHD3

abhydrolase domain containing 3

chr5_+_56469775 0.233 ENST00000424459.3
GPBP1
GC-rich promoter binding protein 1
chr6_+_29910301 0.228 ENST00000376809.5
ENST00000376802.2
HLA-A

major histocompatibility complex, class I, A

chr4_-_159644507 0.227 ENST00000307720.3
PPID
peptidylprolyl isomerase D
chr6_+_44215603 0.222 ENST00000371554.1
HSP90AB1
heat shock protein 90kDa alpha (cytosolic), class B member 1
chr16_-_23568651 0.220 ENST00000563232.1
ENST00000563459.1
ENST00000449606.1
EARS2


glutamyl-tRNA synthetase 2, mitochondrial


chr18_+_57567180 0.220 ENST00000316660.6
ENST00000269518.9
PMAIP1

phorbol-12-myristate-13-acetate-induced protein 1

chr1_+_154966058 0.214 ENST00000392487.1
LENEP
lens epithelial protein
chrX_-_102942961 0.214 ENST00000434230.1
ENST00000418819.1
ENST00000360458.1
MORF4L2


mortality factor 4 like 2


chr13_-_31191642 0.204 ENST00000405805.1
HMGB1
high mobility group box 1
chr22_+_29168652 0.203 ENST00000249064.4
ENST00000444523.1
ENST00000448492.2
ENST00000421503.2
CCDC117



coiled-coil domain containing 117



chr11_+_65266507 0.202 ENST00000544868.1
MALAT1
metastasis associated lung adenocarcinoma transcript 1 (non-protein coding)
chr15_+_44092784 0.200 ENST00000458412.1
HYPK
huntingtin interacting protein K
chr2_+_198365095 0.196 ENST00000409468.1
HSPE1
heat shock 10kDa protein 1
chr17_+_73996987 0.195 ENST00000588812.1
ENST00000448471.1
CDK3

cyclin-dependent kinase 3

chr5_-_133706695 0.193 ENST00000521755.1
ENST00000523054.1
ENST00000435240.2
ENST00000609654.1
ENST00000536186.1
ENST00000609383.1
CDKL3





cyclin-dependent kinase-like 3





chr9_-_13279406 0.193 ENST00000546205.1
MPDZ
multiple PDZ domain protein
chr16_+_76587314 0.192 ENST00000563764.1
RP11-58C22.1
Uncharacterized protein
chr2_+_223162866 0.183 ENST00000295226.1
CCDC140
coiled-coil domain containing 140
chr22_+_17082732 0.180 ENST00000558085.2
ENST00000592918.1
ENST00000400593.2
ENST00000592107.1
ENST00000426585.1
ENST00000591299.1
TPTEP1





transmembrane phosphatase with tensin homology pseudogene 1





chr22_-_24181174 0.180 ENST00000318109.7
ENST00000406855.3
ENST00000404056.1
ENST00000476077.1
DERL3



derlin 3



chr2_-_68479614 0.179 ENST00000234310.3
PPP3R1
protein phosphatase 3, regulatory subunit B, alpha
chrX_-_102943022 0.172 ENST00000433176.2
MORF4L2
mortality factor 4 like 2
chrX_-_39923656 0.170 ENST00000413905.1
BCOR
BCL6 corepressor
chr20_+_36149602 0.163 ENST00000062104.2
ENST00000346199.2
NNAT

neuronatin

chr5_+_133706865 0.163 ENST00000265339.2
UBE2B
ubiquitin-conjugating enzyme E2B
chrX_-_55515635 0.158 ENST00000500968.3
USP51
ubiquitin specific peptidase 51
chr8_-_37594944 0.157 ENST00000330539.1
RP11-863K10.7
Uncharacterized protein
chr22_+_29664248 0.156 ENST00000406548.1
ENST00000437155.2
ENST00000415761.1
ENST00000331029.7
EWSR1



EWS RNA-binding protein 1



chr20_+_19867150 0.156 ENST00000255006.6
RIN2
Ras and Rab interactor 2
chr1_-_228613026 0.152 ENST00000366696.1
HIST3H3
histone cluster 3, H3
chr1_+_196743912 0.151 ENST00000367425.4
CFHR3
complement factor H-related 3
chr8_+_37594130 0.150 ENST00000518526.1
ENST00000523887.1
ENST00000276461.5
ERLIN2


ER lipid raft associated 2


chr19_-_49567124 0.150 ENST00000301411.3
NTF4
neurotrophin 4
chrX_+_108780062 0.147 ENST00000372106.1
NXT2
nuclear transport factor 2-like export factor 2
chr1_-_53704157 0.146 ENST00000371466.4
ENST00000371470.3
MAGOH

mago-nashi homolog, proliferation-associated (Drosophila)

chrX_+_108779870 0.145 ENST00000372107.1
NXT2
nuclear transport factor 2-like export factor 2
chr11_-_47869865 0.143 ENST00000530326.1
ENST00000532747.1
NUP160

nucleoporin 160kDa

chr4_-_6383594 0.141 ENST00000335585.5
PPP2R2C
protein phosphatase 2, regulatory subunit B, gamma
chr17_-_61850894 0.137 ENST00000403162.3
ENST00000582252.1
ENST00000225726.5
CCDC47


coiled-coil domain containing 47


chr2_+_203130439 0.134 ENST00000264279.5
NOP58
NOP58 ribonucleoprotein
chr3_+_130612803 0.134 ENST00000510168.1
ENST00000508532.1
ATP2C1

ATPase, Ca++ transporting, type 2C, member 1

chr11_-_1587166 0.134 ENST00000331588.4
DUSP8
dual specificity phosphatase 8
chr22_+_41253080 0.132 ENST00000541156.1
ENST00000414396.1
ENST00000357137.4
XPNPEP3


X-prolyl aminopeptidase (aminopeptidase P) 3, putative


chr13_-_41593425 0.128 ENST00000239882.3
ELF1
E74-like factor 1 (ets domain transcription factor)
chr17_+_78194205 0.128 ENST00000573809.1
ENST00000361193.3
ENST00000574967.1
ENST00000576126.1
ENST00000411502.3
ENST00000546047.2
SLC26A11





solute carrier family 26 (anion exchanger), member 11





chr1_+_196857144 0.127 ENST00000367416.2
ENST00000251424.4
ENST00000367418.2
CFHR4


complement factor H-related 4


chr3_+_39509163 0.126 ENST00000436143.2
ENST00000441980.2
ENST00000311042.6
MOBP


myelin-associated oligodendrocyte basic protein


chr15_+_79165222 0.126 ENST00000559930.1
MORF4L1
mortality factor 4 like 1
chr11_-_47870019 0.126 ENST00000378460.2
NUP160
nucleoporin 160kDa
chr2_+_198365122 0.126 ENST00000604458.1
HSPE1-MOB4
HSPE1-MOB4 readthrough
chr16_-_8955570 0.122 ENST00000567554.1
CARHSP1
calcium regulated heat stable protein 1, 24kDa
chr14_-_23388338 0.120 ENST00000555209.1
ENST00000554256.1
ENST00000557403.1
ENST00000557549.1
ENST00000555676.1
ENST00000557571.1
ENST00000557464.1
ENST00000554618.1
ENST00000556862.1
ENST00000555722.1
ENST00000346528.5
ENST00000542016.2
ENST00000399922.2
ENST00000557227.1
ENST00000359890.3
RBM23














RNA binding motif protein 23














chr15_+_79165112 0.119 ENST00000426013.2
MORF4L1
mortality factor 4 like 1
chr19_+_50354462 0.118 ENST00000601675.1
PTOV1
prostate tumor overexpressed 1
chr11_-_62457371 0.118 ENST00000317449.4
LRRN4CL
LRRN4 C-terminal like
chr14_+_63671105 0.117 ENST00000316754.3
RHOJ
ras homolog family member J
chr8_+_143916217 0.115 ENST00000220940.1
GML
glycosylphosphatidylinositol anchored molecule like
chr19_+_2269485 0.115 ENST00000582888.4
ENST00000602676.2
ENST00000322297.4
ENST00000583542.4
OAZ1



ornithine decarboxylase antizyme 1



chr15_+_79165151 0.114 ENST00000331268.5
MORF4L1
mortality factor 4 like 1
chr11_+_65770227 0.114 ENST00000527348.1
BANF1
barrier to autointegration factor 1
chr15_-_86338100 0.111 ENST00000536947.1
KLHL25
kelch-like family member 25
chr2_-_97405775 0.108 ENST00000264963.4
ENST00000537039.1
ENST00000377079.4
ENST00000426463.2
ENST00000534882.1
LMAN2L




lectin, mannose-binding 2-like




chr16_-_8955601 0.105 ENST00000569398.1
ENST00000568968.1
CARHSP1

calcium regulated heat stable protein 1, 24kDa

chr17_-_54911250 0.105 ENST00000575658.1
ENST00000397861.2
C17orf67

chromosome 17 open reading frame 67

chr19_+_50354393 0.104 ENST00000391842.1
PTOV1
prostate tumor overexpressed 1
chr12_+_49121213 0.101 ENST00000548380.1
LINC00935
long intergenic non-protein coding RNA 935
chr19_+_50354430 0.100 ENST00000599732.1
PTOV1
prostate tumor overexpressed 1
chr5_+_56469939 0.099 ENST00000506184.2
GPBP1
GC-rich promoter binding protein 1
chrX_-_154563889 0.099 ENST00000369449.2
ENST00000321926.4
CLIC2

chloride intracellular channel 2

chr14_-_23540747 0.098 ENST00000555566.1
ENST00000338631.6
ENST00000557515.1
ENST00000397341.3
ACIN1



apoptotic chromatin condensation inducer 1



chr18_+_13611763 0.094 ENST00000585931.1
LDLRAD4
low density lipoprotein receptor class A domain containing 4
chr16_+_28875126 0.094 ENST00000359285.5
ENST00000538342.1
SH2B1

SH2B adaptor protein 1

chr11_+_20385666 0.093 ENST00000532081.1
ENST00000531058.1
HTATIP2

HIV-1 Tat interactive protein 2, 30kDa

chr19_-_49565254 0.093 ENST00000593537.1
NTF4
neurotrophin 4
chr20_-_23669590 0.092 ENST00000217423.3
CST4
cystatin S
chr21_-_40720974 0.092 ENST00000380748.1
HMGN1
high mobility group nucleosome binding domain 1
chr11_+_65769946 0.091 ENST00000533166.1
BANF1
barrier to autointegration factor 1
chr21_+_31768348 0.089 ENST00000355459.2
KRTAP13-1
keratin associated protein 13-1
chr11_-_10590238 0.086 ENST00000256178.3
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr1_-_156252590 0.086 ENST00000361813.5
ENST00000368267.5
SMG5

SMG5 nonsense mediated mRNA decay factor

chr20_+_5451845 0.083 ENST00000430097.2
RP5-828H9.1
RP5-828H9.1
chr11_+_65769550 0.077 ENST00000312175.2
ENST00000445560.2
ENST00000530204.1
BANF1


barrier to autointegration factor 1


chr21_+_44394742 0.076 ENST00000432907.2
PKNOX1
PBX/knotted 1 homeobox 1
chr8_+_140943416 0.074 ENST00000507535.3
C8orf17
chromosome 8 open reading frame 17
chr12_-_9885888 0.074 ENST00000327839.3
CLECL1
C-type lectin-like 1
chrX_+_150345054 0.067 ENST00000218316.3
GPR50
G protein-coupled receptor 50
chr19_+_782755 0.067 ENST00000606242.1
ENST00000586061.1
AC006273.5

AC006273.5

chr6_-_76782371 0.066 ENST00000369950.3
ENST00000369963.3
IMPG1

interphotoreceptor matrix proteoglycan 1

chr11_+_63953691 0.066 ENST00000543847.1
STIP1
stress-induced-phosphoprotein 1
chr11_+_63953587 0.063 ENST00000305218.4
ENST00000538945.1
STIP1

stress-induced-phosphoprotein 1

chr1_-_99470368 0.063 ENST00000263177.4
LPPR5
Lipid phosphate phosphatase-related protein type 5
chr12_+_65563329 0.061 ENST00000308330.2
LEMD3
LEM domain containing 3
chr1_+_156308245 0.059 ENST00000368253.2
ENST00000470342.1
ENST00000368254.1
TSACC


TSSK6 activating co-chaperone


chr14_-_68141535 0.057 ENST00000554659.1
VTI1B
vesicle transport through interaction with t-SNAREs 1B
chr22_+_29664305 0.055 ENST00000414183.2
ENST00000333395.6
ENST00000455726.1
ENST00000332035.6
EWSR1



EWS RNA-binding protein 1



chr21_-_40720995 0.055 ENST00000380749.5
HMGN1
high mobility group nucleosome binding domain 1
chrX_-_152989798 0.054 ENST00000441714.1
ENST00000442093.1
ENST00000429550.1
ENST00000345046.6
BCAP31



B-cell receptor-associated protein 31



chr19_+_751122 0.053 ENST00000215582.6
MISP
mitotic spindle positioning
chr11_+_20385231 0.052 ENST00000530266.1
ENST00000421577.2
ENST00000443524.2
ENST00000419348.2
HTATIP2



HIV-1 Tat interactive protein 2, 30kDa



chr15_-_86338134 0.052 ENST00000337975.5
KLHL25
kelch-like family member 25
chrX_+_15767971 0.051 ENST00000479740.1
ENST00000454127.2
CA5B

carbonic anhydrase VB, mitochondrial

chr9_-_6015607 0.042 ENST00000259569.5
RANBP6
RAN binding protein 6
chr11_-_111781554 0.041 ENST00000526167.1
ENST00000528961.1
CRYAB

crystallin, alpha B

chr3_+_138066539 0.040 ENST00000289104.4
MRAS
muscle RAS oncogene homolog
chr5_+_118690466 0.040 ENST00000503646.1
TNFAIP8
tumor necrosis factor, alpha-induced protein 8
chr3_+_186501336 0.039 ENST00000323963.5
ENST00000440191.2
ENST00000356531.5
EIF4A2


eukaryotic translation initiation factor 4A2


chr1_+_156308403 0.037 ENST00000481479.1
ENST00000368252.1
ENST00000466306.1
ENST00000368251.1
TSACC



TSSK6 activating co-chaperone



chr15_-_58357932 0.037 ENST00000347587.3
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr11_-_10590118 0.037 ENST00000529598.1
LYVE1
lymphatic vessel endothelial hyaluronan receptor 1
chr16_+_68119764 0.035 ENST00000570212.1
ENST00000562926.1
NFATC3

nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3

chr8_-_57359131 0.034 ENST00000518974.1
ENST00000523051.1
ENST00000518770.1
ENST00000451791.2
PENK



proenkephalin



chr2_-_208989225 0.033 ENST00000264376.4
CRYGD
crystallin, gamma D
chrX_-_107225600 0.033 ENST00000302917.1
TEX13B
testis expressed 13B
chr19_+_3224700 0.032 ENST00000292672.2
ENST00000541430.2
CELF5

CUGBP, Elav-like family member 5

chr15_-_58357866 0.032 ENST00000537372.1
ALDH1A2
aldehyde dehydrogenase 1 family, member A2
chr5_+_133707252 0.032 ENST00000506787.1
ENST00000507277.1
UBE2B

ubiquitin-conjugating enzyme E2B

chr2_-_69664586 0.030 ENST00000303698.3
ENST00000394305.1
ENST00000410022.2
NFU1


NFU1 iron-sulfur cluster scaffold homolog (S. cerevisiae)


chr11_+_20385327 0.029 ENST00000451739.2
ENST00000532505.1
HTATIP2

HIV-1 Tat interactive protein 2, 30kDa

chr5_+_446253 0.028 ENST00000315013.5
EXOC3
exocyst complex component 3
chrX_+_150866779 0.028 ENST00000370353.3
PRRG3
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr16_+_29789561 0.027 ENST00000400752.4
ZG16
zymogen granule protein 16
chr19_-_42721819 0.025 ENST00000336034.4
ENST00000598200.1
ENST00000598727.1
ENST00000596251.1
DEDD2



death effector domain containing 2



chr4_-_22517620 0.024 ENST00000502482.1
ENST00000334304.5
GPR125

G protein-coupled receptor 125

chr18_-_6929829 0.023 ENST00000583840.1
ENST00000581571.1
ENST00000578497.1
ENST00000579012.1
LINC00668



long intergenic non-protein coding RNA 668



chr17_+_34087888 0.023 ENST00000586491.1
ENST00000588628.1
ENST00000285023.4
C17orf50


chromosome 17 open reading frame 50


chr7_-_26240357 0.020 ENST00000354667.4
ENST00000356674.7
HNRNPA2B1

heterogeneous nuclear ribonucleoprotein A2/B1

chr9_-_4666337 0.019 ENST00000381890.5
SPATA6L
spermatogenesis associated 6-like
chr12_+_110940005 0.017 ENST00000409246.1
ENST00000392672.4
ENST00000409300.1
ENST00000409425.1
RAD9B



RAD9 homolog B (S. pombe)



chr15_+_45028753 0.017 ENST00000338264.4
TRIM69
tripartite motif containing 69

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0002514 B cell tolerance induction(GO:0002514) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663)
0.5 1.5 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.3 1.7 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.3 1.6 GO:1904764 negative regulation of fibril organization(GO:1902904) chaperone-mediated autophagy translocation complex disassembly(GO:1904764)
0.3 2.2 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.3 0.8 GO:0001798 positive regulation of type IIa hypersensitivity(GO:0001798) positive regulation of type II hypersensitivity(GO:0002894)
0.2 0.7 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.2 1.1 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.2 2.0 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.2 0.6 GO:0072658 maintenance of protein location in membrane(GO:0072658) maintenance of protein location in plasma membrane(GO:0072660) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 0.5 GO:0043335 protein unfolding(GO:0043335)
0.1 0.3 GO:0042214 terpene metabolic process(GO:0042214)
0.1 0.8 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)
0.1 0.4 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.3 GO:0032223 negative regulation of synaptic transmission, cholinergic(GO:0032223) neurotransmitter receptor biosynthetic process(GO:0045212)
0.1 0.6 GO:0090206 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.1 0.3 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 2.7 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.1 0.2 GO:0006424 glutamyl-tRNA aminoacylation(GO:0006424)
0.1 0.2 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.2 GO:0007402 ganglion mother cell fate determination(GO:0007402)
0.1 0.2 GO:0009956 radial pattern formation(GO:0009956)
0.1 0.2 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.2 GO:1903660 negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.2 GO:0032072 plasmacytoid dendritic cell activation(GO:0002270) T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) regulation of restriction endodeoxyribonuclease activity(GO:0032072)
0.0 0.2 GO:0050821 protein stabilization(GO:0050821)
0.0 0.2 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 1.4 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:1902998 macrophage proliferation(GO:0061517) microglial cell proliferation(GO:0061518) regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.5 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.0 0.6 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.0 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.3 GO:0015074 DNA integration(GO:0015074)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.2 GO:0002480 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent(GO:0002480)
0.0 0.2 GO:0010917 negative regulation of mitochondrial membrane potential(GO:0010917)
0.0 0.3 GO:0060965 negative regulation of gene silencing by miRNA(GO:0060965)
0.0 0.1 GO:0048254 snoRNA localization(GO:0048254)
0.0 0.2 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.3 GO:1990001 inhibition of cysteine-type endopeptidase activity involved in apoptotic process(GO:1990001)
0.0 0.2 GO:0045023 G0 to G1 transition(GO:0045023)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.3 GO:0030217 T cell differentiation(GO:0030217)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.2 1.6 GO:0098575 lumenal side of lysosomal membrane(GO:0098575)
0.1 0.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.8 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 2.2 GO:0071682 endocytic vesicle lumen(GO:0071682)
0.1 0.8 GO:0036157 outer dynein arm(GO:0036157)
0.1 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.4 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 2.0 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 0.3 GO:0043083 synaptic cleft(GO:0043083)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.4 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.2 2.4 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.2 2.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.2 GO:0002134 pyrimidine nucleoside binding(GO:0001884) UTP binding(GO:0002134) sulfonylurea receptor binding(GO:0017098) pyrimidine ribonucleoside binding(GO:0032551)
0.1 0.2 GO:0004818 glutamate-tRNA ligase activity(GO:0004818)
0.1 0.3 GO:0003990 acetylcholinesterase activity(GO:0003990)
0.1 0.5 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.1 0.5 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 0.5 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.2 GO:0052740 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.0 2.5 GO:0051879 Hsp90 protein binding(GO:0051879)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.7 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.2 GO:0010858 calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 1.1 GO:0019239 deaminase activity(GO:0019239)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 1.7 GO:0019003 GDP binding(GO:0019003)
0.0 0.7 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.7 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 0.2 GO:0004723 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723)
0.0 0.4 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.6 GO:0030507 spectrin binding(GO:0030507)
0.0 0.6 GO:0015485 cholesterol binding(GO:0015485)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID_ERB_GENOMIC_PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID_LIS1_PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 2.1 PID_CMYB_PATHWAY C-MYB transcription factor network
0.0 0.5 PID_ERBB_NETWORK_PATHWAY ErbB receptor signaling network
0.0 1.1 PID_ATF2_PATHWAY ATF-2 transcription factor network

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.1 REACTOME_PURINE_CATABOLISM Genes involved in Purine catabolism
0.1 2.0 REACTOME_AMINO_ACID_SYNTHESIS_AND_INTERCONVERSION_TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.6 REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.3 REACTOME_APOBEC3G_MEDIATED_RESISTANCE_TO_HIV1_INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 0.2 REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.5 REACTOME_TETRAHYDROBIOPTERIN_BH4_SYNTHESIS_RECYCLING_SALVAGE_AND_REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.7 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME_ACTIVATION_OF_BH3_ONLY_PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME_THE_NLRP3_INFLAMMASOME Genes involved in The NLRP3 inflammasome