Motif ID: ISL1

Z-value: 0.494


Transcription factors associated with ISL1:

Gene SymbolEntrez IDGene Name
ISL1 ENSG00000016082.10 ISL1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
ISL1hg19_v2_chr5_+_50678921_50678921-0.203.4e-01Click!


Activity profile for motif ISL1.

activity profile for motif ISL1


Sorted Z-values histogram for motif ISL1

Sorted Z-values for motif ISL1



Network of associatons between targets according to the STRING database.



First level regulatory network of ISL1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_102668879 0.946 ENST00000315274.6
MMP1
matrix metallopeptidase 1 (interstitial collagenase)
chr8_+_26371763 0.736 ENST00000521913.1
DPYSL2
dihydropyrimidinase-like 2
chrX_+_135252050 0.612 ENST00000449474.1
ENST00000345434.3
FHL1

four and a half LIM domains 1

chr12_-_30887948 0.600 ENST00000433722.2
CAPRIN2
caprin family member 2
chrX_+_135251835 0.562 ENST00000456445.1
FHL1
four and a half LIM domains 1
chr5_+_137203465 0.556 ENST00000239926.4
MYOT
myotilin
chrX_+_135251783 0.551 ENST00000394153.2
FHL1
four and a half LIM domains 1
chr19_-_50143452 0.547 ENST00000246792.3
RRAS
related RAS viral (r-ras) oncogene homolog
chr6_+_167704838 0.445 ENST00000366829.2
UNC93A
unc-93 homolog A (C. elegans)
chrX_+_79675965 0.436 ENST00000308293.5
FAM46D
family with sequence similarity 46, member D
chr11_+_60995849 0.408 ENST00000537932.1
PGA4
pepsinogen 4, group I (pepsinogen A)
chr16_-_67517716 0.405 ENST00000290953.2
AGRP
agouti related protein homolog (mouse)
chr6_+_167704798 0.399 ENST00000230256.3
UNC93A
unc-93 homolog A (C. elegans)
chr2_-_208030647 0.388 ENST00000309446.6
KLF7
Kruppel-like factor 7 (ubiquitous)
chr22_+_40390930 0.379 ENST00000333407.6
FAM83F
family with sequence similarity 83, member F
chr4_+_8201091 0.372 ENST00000382521.3
ENST00000245105.3
ENST00000457650.2
ENST00000539824.1
SH3TC1



SH3 domain and tetratricopeptide repeats 1



chr10_-_17659234 0.367 ENST00000466335.1
PTPLA
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A
chr3_+_121774202 0.343 ENST00000469710.1
ENST00000493101.1
ENST00000330540.2
ENST00000264468.5
CD86



CD86 molecule



chr2_+_211421262 0.338 ENST00000233072.5
CPS1
carbamoyl-phosphate synthase 1, mitochondrial
chr9_-_113761720 0.337 ENST00000541779.1
ENST00000374430.2
LPAR1

lysophosphatidic acid receptor 1

chr10_-_17659357 0.326 ENST00000326961.6
ENST00000361271.3
PTPLA

protein tyrosine phosphatase-like (proline instead of catalytic arginine), member A

chr10_+_17270214 0.324 ENST00000544301.1
VIM
vimentin
chr12_-_28124903 0.322 ENST00000395872.1
ENST00000354417.3
ENST00000201015.4
PTHLH


parathyroid hormone-like hormone


chr1_+_82266053 0.320 ENST00000370715.1
ENST00000370713.1
ENST00000319517.6
ENST00000370717.2
ENST00000394879.1
ENST00000271029.4
ENST00000335786.5
LPHN2






latrophilin 2






chr11_-_107729887 0.318 ENST00000525815.1
SLC35F2
solute carrier family 35, member F2
chr3_+_158787041 0.304 ENST00000471575.1
ENST00000476809.1
ENST00000485419.1
IQCJ-SCHIP1


IQCJ-SCHIP1 readthrough


chr17_-_57229155 0.298 ENST00000584089.1
SKA2
spindle and kinetochore associated complex subunit 2
chr9_+_131084846 0.294 ENST00000608951.1
COQ4
coenzyme Q4
chr12_+_1099675 0.287 ENST00000545318.2
ERC1
ELKS/RAB6-interacting/CAST family member 1
chr3_-_149095652 0.285 ENST00000305366.3
TM4SF1
transmembrane 4 L six family member 1
chr7_+_20687017 0.282 ENST00000258738.6
ABCB5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chr2_+_158114051 0.277 ENST00000259056.4
GALNT5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5 (GalNAc-T5)
chr1_-_114430169 0.275 ENST00000393316.3
BCL2L15
BCL2-like 15
chr6_+_35996859 0.270 ENST00000472333.1
MAPK14
mitogen-activated protein kinase 14
chr18_+_21529811 0.264 ENST00000588004.1
LAMA3
laminin, alpha 3
chr2_+_219472637 0.255 ENST00000417849.1
PLCD4
phospholipase C, delta 4
chr5_+_137203557 0.253 ENST00000515645.1
MYOT
myotilin
chr8_+_42873548 0.244 ENST00000533338.1
ENST00000534420.1
HOOK3
RP11-598P20.5
hook microtubule-tethering protein 3
Uncharacterized protein
chr13_-_99910673 0.243 ENST00000397473.2
ENST00000397470.2
GPR18

G protein-coupled receptor 18

chr12_+_96883347 0.239 ENST00000524981.4
ENST00000298953.3
C12orf55

chromosome 12 open reading frame 55

chr4_-_77328458 0.236 ENST00000388914.3
ENST00000434846.2
CCDC158

coiled-coil domain containing 158

chr2_+_28618532 0.228 ENST00000545753.1
FOSL2
FOS-like antigen 2
chr10_-_95241951 0.227 ENST00000358334.5
ENST00000359263.4
ENST00000371488.3
MYOF


myoferlin


chr2_-_89247338 0.223 ENST00000496168.1
IGKV1-5
immunoglobulin kappa variable 1-5
chr10_-_95242044 0.221 ENST00000371501.4
ENST00000371502.4
ENST00000371489.1
MYOF


myoferlin


chr13_-_99667960 0.219 ENST00000448493.2
DOCK9
dedicator of cytokinesis 9
chr15_-_72767490 0.219 ENST00000565181.1
RP11-1007O24.3
RP11-1007O24.3
chr15_-_55541227 0.218 ENST00000566877.1
RAB27A
RAB27A, member RAS oncogene family
chr7_+_13141097 0.215 ENST00000411542.1
AC011288.2
AC011288.2
chr1_-_197169672 0.207 ENST00000367405.4
ZBTB41
zinc finger and BTB domain containing 41
chr8_+_70404996 0.204 ENST00000402687.4
ENST00000419716.3
SULF1

sulfatase 1

chr17_-_64225508 0.198 ENST00000205948.6
APOH
apolipoprotein H (beta-2-glycoprotein I)
chr14_+_37126765 0.194 ENST00000402703.2
PAX9
paired box 9
chr20_-_25320367 0.191 ENST00000450393.1
ENST00000491682.1
ABHD12

abhydrolase domain containing 12

chr4_-_186877806 0.191 ENST00000355634.5
SORBS2
sorbin and SH3 domain containing 2
chr5_+_137203541 0.191 ENST00000421631.2
MYOT
myotilin
chr3_-_113897899 0.187 ENST00000383673.2
ENST00000295881.7
DRD3

dopamine receptor D3

chr2_-_220034712 0.182 ENST00000409370.2
ENST00000430764.1
ENST00000409878.3
SLC23A3


solute carrier family 23, member 3


chr1_+_15986364 0.181 ENST00000345034.1
RSC1A1
regulatory solute carrier protein, family 1, member 1
chr15_+_48498480 0.181 ENST00000380993.3
ENST00000396577.3
SLC12A1

solute carrier family 12 (sodium/potassium/chloride transporter), member 1

chr11_-_66496430 0.178 ENST00000533211.1
SPTBN2
spectrin, beta, non-erythrocytic 2
chr1_+_3773825 0.177 ENST00000378209.3
ENST00000338895.3
ENST00000378212.2
ENST00000341385.3
DFFB



DNA fragmentation factor, 40kDa, beta polypeptide (caspase-activated DNase)



chr3_-_185538849 0.177 ENST00000421047.2
IGF2BP2
insulin-like growth factor 2 mRNA binding protein 2
chr5_+_34757309 0.177 ENST00000397449.1
RAI14
retinoic acid induced 14
chr11_+_30252549 0.176 ENST00000254122.3
ENST00000417547.1
FSHB

follicle stimulating hormone, beta polypeptide

chr1_-_119682812 0.175 ENST00000537870.1
WARS2
tryptophanyl tRNA synthetase 2, mitochondrial
chr16_+_2198604 0.174 ENST00000210187.6
RAB26
RAB26, member RAS oncogene family
chr12_+_93096759 0.173 ENST00000544406.2
C12orf74
chromosome 12 open reading frame 74
chr18_+_616672 0.173 ENST00000338387.7
CLUL1
clusterin-like 1 (retinal)
chr4_+_169418255 0.170 ENST00000505667.1
ENST00000511948.1
PALLD

palladin, cytoskeletal associated protein

chr6_+_168418553 0.166 ENST00000354419.2
ENST00000351261.3
KIF25

kinesin family member 25

chr6_+_31707725 0.163 ENST00000375755.3
ENST00000375742.3
ENST00000375750.3
ENST00000425703.1
ENST00000534153.4
ENST00000375703.3
ENST00000375740.3
MSH5






mutS homolog 5






chr12_+_93096619 0.161 ENST00000397833.3
C12orf74
chromosome 12 open reading frame 74
chr10_+_135340859 0.160 ENST00000252945.3
ENST00000421586.1
ENST00000418356.1
CYP2E1


cytochrome P450, family 2, subfamily E, polypeptide 1


chr8_+_26247878 0.159 ENST00000518611.1
BNIP3L
BCL2/adenovirus E1B 19kDa interacting protein 3-like
chr22_-_36784035 0.155 ENST00000216181.5
MYH9
myosin, heavy chain 9, non-muscle
chr7_+_93535817 0.153 ENST00000248572.5
GNGT1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1
chr4_+_169418195 0.152 ENST00000261509.6
ENST00000335742.7
PALLD

palladin, cytoskeletal associated protein

chr8_+_53850991 0.151 ENST00000331251.3
NPBWR1
neuropeptides B/W receptor 1
chr11_+_120973375 0.151 ENST00000264037.2
TECTA
tectorin alpha
chr3_-_27498235 0.150 ENST00000295736.5
ENST00000428386.1
ENST00000428179.1
SLC4A7


solute carrier family 4, sodium bicarbonate cotransporter, member 7


chrX_+_49832231 0.149 ENST00000376108.3
CLCN5
chloride channel, voltage-sensitive 5
chr7_+_99724317 0.148 ENST00000398075.2
ENST00000421390.1
MBLAC1

metallo-beta-lactamase domain containing 1

chr2_+_202937972 0.148 ENST00000541917.1
ENST00000295844.3
AC079354.1

uncharacterized protein KIAA2012

chr1_-_157670647 0.142 ENST00000368184.3
FCRL3
Fc receptor-like 3
chr7_-_122342988 0.141 ENST00000434824.1
RNF148
ring finger protein 148
chr13_-_52027134 0.138 ENST00000311234.4
ENST00000425000.1
ENST00000463928.1
ENST00000442263.3
ENST00000398119.2
INTS6




integrator complex subunit 6




chr1_-_95391315 0.133 ENST00000545882.1
ENST00000415017.1
CNN3

calponin 3, acidic

chr9_-_134585221 0.132 ENST00000372190.3
ENST00000427994.1
RAPGEF1

Rap guanine nucleotide exchange factor (GEF) 1

chr1_-_100598444 0.131 ENST00000535161.1
ENST00000287482.5
SASS6

spindle assembly 6 homolog (C. elegans)

chr1_+_150980889 0.131 ENST00000450884.1
ENST00000271620.3
ENST00000271619.8
ENST00000368937.1
ENST00000431193.1
ENST00000368936.1
PRUNE





prune exopolyphosphatase





chr2_+_171034646 0.129 ENST00000409044.3
ENST00000408978.4
MYO3B

myosin IIIB

chr17_-_15501932 0.129 ENST00000583965.1
CDRT1
CMT1A duplicated region transcript 1
chr6_-_117150198 0.128 ENST00000310357.3
ENST00000368549.3
ENST00000530250.1
GPRC6A


G protein-coupled receptor, family C, group 6, member A


chr18_+_616711 0.127 ENST00000579494.1
CLUL1
clusterin-like 1 (retinal)
chr19_+_39687596 0.127 ENST00000339852.4
NCCRP1
non-specific cytotoxic cell receptor protein 1 homolog (zebrafish)
chr5_+_135468516 0.127 ENST00000507118.1
ENST00000511116.1
ENST00000545279.1
ENST00000545620.1
SMAD5



SMAD family member 5



chr8_-_7220490 0.127 ENST00000400078.2
ZNF705G
zinc finger protein 705G
chr2_+_207804278 0.126 ENST00000272852.3
CPO
carboxypeptidase O
chr4_-_87281196 0.124 ENST00000359221.3
MAPK10
mitogen-activated protein kinase 10
chr10_-_115613828 0.123 ENST00000361384.2
DCLRE1A
DNA cross-link repair 1A
chr7_-_122342966 0.122 ENST00000447240.1
RNF148
ring finger protein 148
chr14_+_62585332 0.122 ENST00000554895.1
LINC00643
long intergenic non-protein coding RNA 643
chr11_+_64018955 0.115 ENST00000279230.6
ENST00000540288.1
ENST00000325234.5
PLCB3


phospholipase C, beta 3 (phosphatidylinositol-specific)


chr20_+_60174827 0.114 ENST00000543233.1
CDH4
cadherin 4, type 1, R-cadherin (retinal)
chrX_-_15683147 0.113 ENST00000380342.3
TMEM27
transmembrane protein 27
chr3_+_151451707 0.113 ENST00000356517.3
AADACL2
arylacetamide deacetylase-like 2
chrX_-_92928557 0.111 ENST00000373079.3
ENST00000475430.2
NAP1L3

nucleosome assembly protein 1-like 3

chr9_+_131084815 0.111 ENST00000300452.3
ENST00000609948.1
COQ4

coenzyme Q4

chr4_-_168155169 0.111 ENST00000534949.1
ENST00000535728.1
SPOCK3

sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 3

chr3_+_38307293 0.109 ENST00000311856.4
SLC22A13
solute carrier family 22 (organic anion/urate transporter), member 13
chr12_-_24102576 0.109 ENST00000537393.1
ENST00000309359.1
ENST00000381381.2
ENST00000451604.2
SOX5



SRY (sex determining region Y)-box 5



chr15_-_43594453 0.108 ENST00000452443.2
TGM7
transglutaminase 7
chr8_-_131399110 0.105 ENST00000521426.1
ASAP1
ArfGAP with SH3 domain, ankyrin repeat and PH domain 1
chr17_-_2996290 0.105 ENST00000331459.1
OR1D2
olfactory receptor, family 1, subfamily D, member 2
chr4_-_87281224 0.104 ENST00000395169.3
ENST00000395161.2
MAPK10

mitogen-activated protein kinase 10

chr7_+_93535866 0.104 ENST00000429473.1
ENST00000430875.1
ENST00000428834.1
GNGT1


guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1


chr5_+_32788945 0.103 ENST00000326958.1
AC026703.1
AC026703.1
chr12_-_11139511 0.101 ENST00000506868.1
TAS2R50
taste receptor, type 2, member 50
chr4_+_118955500 0.100 ENST00000296499.5
NDST3
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr12_+_54402790 0.098 ENST00000040584.4
HOXC8
homeobox C8
chr17_+_1933404 0.097 ENST00000263083.6
ENST00000571418.1
DPH1

diphthamide biosynthesis 1

chr19_-_42806842 0.096 ENST00000596265.1
PAFAH1B3
platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)
chrX_+_65382433 0.096 ENST00000374727.3
HEPH
hephaestin
chr12_-_53012343 0.096 ENST00000305748.3
KRT73
keratin 73
chr9_+_27109133 0.095 ENST00000519097.1
ENST00000380036.4
TEK

TEK tyrosine kinase, endothelial

chr13_+_28527647 0.094 ENST00000567234.1
LINC00543
long intergenic non-protein coding RNA 543
chr22_+_30279144 0.093 ENST00000401950.2
ENST00000333027.3
ENST00000445401.1
ENST00000323630.5
ENST00000351488.3
MTMR3




myotubularin related protein 3




chr5_+_32710736 0.091 ENST00000415685.2
NPR3
natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C)
chr1_+_223101757 0.090 ENST00000284476.6
DISP1
dispatched homolog 1 (Drosophila)
chr8_-_70016408 0.090 ENST00000518540.1
RP11-600K15.1
RP11-600K15.1
chr14_-_60337684 0.089 ENST00000267484.5
RTN1
reticulon 1
chr5_+_169659950 0.088 ENST00000593851.1
C5orf58
chromosome 5 open reading frame 58
chr7_+_150811705 0.088 ENST00000335367.3
AGAP3
ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
chr6_-_138820624 0.088 ENST00000343505.5
NHSL1
NHS-like 1
chr6_+_155537771 0.088 ENST00000275246.7
TIAM2
T-cell lymphoma invasion and metastasis 2
chr15_-_62937380 0.088 ENST00000560347.1
ENST00000558940.1
RP11-625H11.1

Uncharacterized protein

chr14_+_20811766 0.087 ENST00000250416.5
ENST00000527915.1
PARP2

poly (ADP-ribose) polymerase 2

chr5_+_52856456 0.084 ENST00000296684.5
ENST00000506765.1
NDUFS4

NADH dehydrogenase (ubiquinone) Fe-S protein 4, 18kDa (NADH-coenzyme Q reductase)

chr12_+_81110684 0.082 ENST00000228644.3
MYF5
myogenic factor 5
chr8_-_19540266 0.082 ENST00000311540.4
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr18_-_5544241 0.082 ENST00000341928.2
ENST00000540638.2
EPB41L3

erythrocyte membrane protein band 4.1-like 3

chr1_+_100111479 0.079 ENST00000263174.4
PALMD
palmdelphin
chr12_-_53045948 0.077 ENST00000309680.3
KRT2
keratin 2
chr8_-_19540086 0.076 ENST00000332246.6
CSGALNACT1
chondroitin sulfate N-acetylgalactosaminyltransferase 1
chr11_-_62783303 0.076 ENST00000336232.2
ENST00000430500.2
SLC22A8

solute carrier family 22 (organic anion transporter), member 8

chr1_-_154458520 0.075 ENST00000486773.1
SHE
Src homology 2 domain containing E
chr3_-_138312971 0.074 ENST00000485115.1
ENST00000484888.1
ENST00000468900.1
ENST00000542237.1
ENST00000481834.1
CEP70




centrosomal protein 70kDa




chr2_+_172543919 0.072 ENST00000452242.1
ENST00000340296.4
DYNC1I2

dynein, cytoplasmic 1, intermediate chain 2

chr11_-_62783276 0.072 ENST00000535878.1
ENST00000545207.1
SLC22A8

solute carrier family 22 (organic anion transporter), member 8

chr20_-_48732472 0.071 ENST00000340309.3
ENST00000415862.2
ENST00000371677.3
ENST00000420027.2
UBE2V1



ubiquitin-conjugating enzyme E2 variant 1



chr5_-_102455801 0.070 ENST00000508629.1
ENST00000399004.2
GIN1

gypsy retrotransposon integrase 1

chr6_+_116575329 0.069 ENST00000430252.2
ENST00000540275.1
ENST00000448740.2
DSE

RP3-486I3.7
dermatan sulfate epimerase

RP3-486I3.7
chr4_-_186877502 0.067 ENST00000431902.1
ENST00000284776.7
ENST00000415274.1
SORBS2


sorbin and SH3 domain containing 2


chr1_+_156024525 0.067 ENST00000368305.4
LAMTOR2
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr1_-_156217875 0.067 ENST00000292291.5
PAQR6
progestin and adipoQ receptor family member VI
chr6_-_128222103 0.066 ENST00000434358.1
ENST00000543064.1
ENST00000368248.2
THEMIS


thymocyte selection associated


chr20_+_42136308 0.066 ENST00000434666.1
ENST00000427442.2
ENST00000439769.1
ENST00000418998.1
L3MBTL1



l(3)mbt-like 1 (Drosophila)



chr3_-_33686925 0.064 ENST00000485378.2
ENST00000313350.6
ENST00000487200.1
CLASP2


cytoplasmic linker associated protein 2


chr19_+_13842559 0.064 ENST00000586600.1
CCDC130
coiled-coil domain containing 130
chr11_+_128563652 0.064 ENST00000527786.2
FLI1
Fli-1 proto-oncogene, ETS transcription factor
chr2_+_99758161 0.063 ENST00000409684.1
C2ORF15
Uncharacterized protein C2orf15
chr6_+_108977520 0.063 ENST00000540898.1
FOXO3
forkhead box O3
chr1_+_156024552 0.063 ENST00000368304.5
ENST00000368302.3
LAMTOR2

late endosomal/lysosomal adaptor, MAPK and MTOR activator 2

chr13_-_45768841 0.061 ENST00000379108.1
KCTD4
potassium channel tetramerization domain containing 4
chr3_+_57875738 0.060 ENST00000417128.1
ENST00000438794.1
SLMAP

sarcolemma associated protein

chr14_-_77495007 0.059 ENST00000238647.3
IRF2BPL
interferon regulatory factor 2 binding protein-like
chr1_-_156217822 0.059 ENST00000368270.1
PAQR6
progestin and adipoQ receptor family member VI
chrX_+_10031499 0.058 ENST00000454666.1
WWC3
WWC family member 3
chrX_-_49965663 0.058 ENST00000376056.2
ENST00000376058.2
ENST00000358526.2
AKAP4


A kinase (PRKA) anchor protein 4


chr3_-_192445289 0.058 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12



fibroblast growth factor 12



chr6_+_31515337 0.058 ENST00000376148.4
ENST00000376145.4
NFKBIL1

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 1

chr21_-_42219065 0.056 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr12_-_6484376 0.056 ENST00000360168.3
ENST00000358945.3
SCNN1A

sodium channel, non-voltage-gated 1 alpha subunit

chr3_-_33686743 0.055 ENST00000333778.6
ENST00000539981.1
CLASP2

cytoplasmic linker associated protein 2

chr15_+_59279851 0.055 ENST00000348370.4
ENST00000434298.1
ENST00000559160.1
RNF111


ring finger protein 111


chr17_+_35732916 0.054 ENST00000586700.1
C17orf78
chromosome 17 open reading frame 78
chr1_-_108231101 0.054 ENST00000544443.1
ENST00000415432.2
VAV3

vav 3 guanine nucleotide exchange factor

chr3_-_49066811 0.052 ENST00000442157.1
ENST00000326739.4
IMPDH2

IMP (inosine 5'-monophosphate) dehydrogenase 2

chrX_-_30327495 0.052 ENST00000453287.1
NR0B1
nuclear receptor subfamily 0, group B, member 1
chr5_-_94417314 0.052 ENST00000505208.1
MCTP1
multiple C2 domains, transmembrane 1
chr17_+_35732955 0.051 ENST00000300618.4
C17orf78
chromosome 17 open reading frame 78
chr19_-_22806764 0.051 ENST00000598042.1
AC011516.2
AC011516.2
chr1_+_113217043 0.050 ENST00000413052.2
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_+_113217073 0.047 ENST00000369645.1
MOV10
Mov10, Moloney leukemia virus 10, homolog (mouse)
chr1_+_206972215 0.047 ENST00000340758.2
IL19
interleukin 19
chr19_-_17488143 0.045 ENST00000599426.1
ENST00000252590.4
PLVAP

plasmalemma vesicle associated protein

chr7_-_44580861 0.045 ENST00000546276.1
ENST00000289547.4
ENST00000381160.3
ENST00000423141.1
NPC1L1



NPC1-like 1



chr21_-_47575481 0.044 ENST00000291670.5
ENST00000397748.1
ENST00000359679.2
ENST00000355384.2
ENST00000397746.3
ENST00000397743.1
FTCD





formimidoyltransferase cyclodeaminase





chr4_+_128554081 0.043 ENST00000335251.6
ENST00000296461.5
INTU

inturned planar cell polarity protein

chr4_+_74347400 0.042 ENST00000226355.3
AFM
afamin
chr2_-_202563414 0.042 ENST00000409474.3
ENST00000315506.7
ENST00000359962.5
MPP4


membrane protein, palmitoylated 4 (MAGUK p55 subfamily member 4)


chr6_+_144904334 0.041 ENST00000367526.4
UTRN
utrophin
chr22_-_43355858 0.041 ENST00000402229.1
ENST00000407585.1
ENST00000453079.1
PACSIN2


protein kinase C and casein kinase substrate in neurons 2


chr16_-_90142338 0.040 ENST00000407825.1
ENST00000449207.2
PRDM7

PR domain containing 7

chr12_-_6484715 0.040 ENST00000228916.2
SCNN1A
sodium channel, non-voltage-gated 1 alpha subunit
chr7_+_90012986 0.039 ENST00000416322.1
CLDN12
claudin 12
chr13_+_78315466 0.038 ENST00000314070.5
ENST00000462234.1
SLAIN1

SLAIN motif family, member 1

chr20_+_36405665 0.036 ENST00000373469.1
CTNNBL1
catenin, beta like 1
chr5_-_142782862 0.035 ENST00000415690.2
NR3C1
nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0002644 negative regulation of tolerance induction(GO:0002644) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.3 GO:0071400 cellular response to oleic acid(GO:0071400)
0.1 0.3 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.1 0.3 GO:0048749 compound eye development(GO:0048749)
0.1 0.3 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835)
0.1 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.2 GO:0046462 monoacylglycerol metabolic process(GO:0046462) monoacylglycerol catabolic process(GO:0052651)
0.0 0.2 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.4 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.2 GO:0050653 chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0050653)
0.0 0.2 GO:1903435 positive regulation of constitutive secretory pathway(GO:1903435)
0.0 0.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.0 0.2 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.4 GO:0001778 plasma membrane repair(GO:0001778)
0.0 0.1 GO:1904562 phosphatidylinositol 5-phosphate metabolic process(GO:1904562)
0.0 0.2 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.0 0.6 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.3 GO:0060020 Bergmann glial cell differentiation(GO:0060020)
0.0 0.2 GO:0010193 response to ozone(GO:0010193)
0.0 0.2 GO:1903923 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.9 GO:0032461 positive regulation of protein oligomerization(GO:0032461)
0.0 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.0 0.2 GO:0042492 gamma-delta T cell differentiation(GO:0042492)
0.0 1.7 GO:0003254 regulation of membrane depolarization(GO:0003254)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0001544 initiation of primordial ovarian follicle growth(GO:0001544)
0.0 0.2 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.7 GO:0060325 face morphogenesis(GO:0060325)
0.0 0.6 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.0 0.1 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:0048842 positive regulation of axon extension involved in axon guidance(GO:0048842)
0.0 0.1 GO:0038180 nerve growth factor signaling pathway(GO:0038180)
0.0 0.1 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0097486 multivesicular body lumen(GO:0097486)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.2 GO:0005826 actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.1 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0035370 UBC13-UEV1A complex(GO:0035370)
0.0 0.2 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:0031089 platelet dense granule lumen(GO:0031089)
0.0 0.1 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0032300 mismatch repair complex(GO:0032300)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004157 dihydropyrimidinase activity(GO:0004157)
0.1 0.3 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.1 0.2 GO:0008955 peptidoglycan glycosyltransferase activity(GO:0008955)
0.0 0.3 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.3 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.3 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.2 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:1990404 protein ADP-ribosylase activity(GO:1990404)
0.0 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 1.3 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.1 GO:0032093 SAM domain binding(GO:0032093)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0047757 chondroitin-glucuronate 5-epimerase activity(GO:0047757)
0.0 0.1 GO:0032184 SUMO polymer binding(GO:0032184)
0.0 0.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 0.2 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.1 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.2 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.0 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0051959 dynein light intermediate chain binding(GO:0051959)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.4 PID_FRA_PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.4 PID_SYNDECAN_3_PATHWAY Syndecan-3-mediated signaling events
0.0 0.3 PID_HEDGEHOG_2PATHWAY Signaling events mediated by the Hedgehog family

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME_CRMPS_IN_SEMA3A_SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.9 REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_ACTIVITY_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.5 REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.3 REACTOME_CD28_DEPENDENT_VAV1_PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.4 REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.2 REACTOME_GLYCOPROTEIN_HORMONES Genes involved in Glycoprotein hormones