Motif ID: MEF2B

Z-value: 0.745


Transcription factors associated with MEF2B:

Gene SymbolEntrez IDGene Name
MEF2B ENSG00000213999.11 MEF2B

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
MEF2Bhg19_v2_chr19_-_19302931_193029740.164.6e-01Click!


Activity profile for motif MEF2B.

activity profile for motif MEF2B


Sorted Z-values histogram for motif MEF2B

Sorted Z-values for motif MEF2B



Network of associatons between targets according to the STRING database.



First level regulatory network of MEF2B

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_131200810 1.810 ENST00000536002.1
ENST00000544034.1
RIMBP2
RP11-662M24.2
RIMS binding protein 2
RP11-662M24.2
chr2_+_233497931 1.179 ENST00000264059.3
EFHD1
EF-hand domain family, member D1
chr16_+_84328252 1.056 ENST00000219454.5
WFDC1
WAP four-disulfide core domain 1
chr16_+_84328429 1.048 ENST00000568638.1
WFDC1
WAP four-disulfide core domain 1
chr2_-_86564776 0.857 ENST00000165698.5
ENST00000541910.1
ENST00000535845.1
REEP1


receptor accessory protein 1


chr8_+_1993173 0.809 ENST00000523438.1
MYOM2
myomesin 2
chr12_-_111358372 0.805 ENST00000548438.1
ENST00000228841.8
MYL2

myosin, light chain 2, regulatory, cardiac, slow

chr8_-_27115931 0.804 ENST00000523048.1
STMN4
stathmin-like 4
chrX_-_63450480 0.803 ENST00000362002.2
ASB12
ankyrin repeat and SOCS box containing 12
chr8_+_1993152 0.802 ENST00000262113.4
MYOM2
myomesin 2
chr18_+_12407895 0.763 ENST00000590956.1
ENST00000336990.4
ENST00000440960.1
ENST00000588729.1
SLMO1



slowmo homolog 1 (Drosophila)



chr17_-_39211463 0.707 ENST00000542910.1
ENST00000398477.1
KRTAP2-2

keratin associated protein 2-2

chr4_+_120056939 0.670 ENST00000307128.5
MYOZ2
myozenin 2
chr8_-_72268889 0.617 ENST00000388742.4
EYA1
eyes absent homolog 1 (Drosophila)
chr8_-_72268968 0.609 ENST00000388740.3
EYA1
eyes absent homolog 1 (Drosophila)
chr17_+_42248063 0.603 ENST00000293414.1
ASB16
ankyrin repeat and SOCS box containing 16
chr6_+_123038689 0.603 ENST00000354275.2
ENST00000368446.1
PKIB

protein kinase (cAMP-dependent, catalytic) inhibitor beta

chr11_-_84634217 0.582 ENST00000524982.1
DLG2
discs, large homolog 2 (Drosophila)
chr4_+_8321882 0.576 ENST00000503186.1
ENST00000509453.1
RP11-774O3.1
RP11-774O3.2
RP11-774O3.1
RP11-774O3.2
chr11_-_84634447 0.573 ENST00000532653.1
DLG2
discs, large homolog 2 (Drosophila)
chr2_+_170366203 0.543 ENST00000284669.1
KLHL41
kelch-like family member 41
chr3_-_52486841 0.509 ENST00000496590.1
TNNC1
troponin C type 1 (slow)
chr2_-_211168332 0.505 ENST00000341685.4
MYL1
myosin, light chain 1, alkali; skeletal, fast
chr14_+_76776957 0.495 ENST00000512784.1
ESRRB
estrogen-related receptor beta
chr3_+_179370517 0.483 ENST00000263966.3
USP13
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr14_-_102704783 0.478 ENST00000522534.1
MOK
MOK protein kinase
chr18_-_47792851 0.471 ENST00000398545.4
CCDC11
coiled-coil domain containing 11
chr3_+_159570722 0.461 ENST00000482804.1
SCHIP1
schwannomin interacting protein 1
chr4_+_37892682 0.457 ENST00000508802.1
ENST00000261439.4
ENST00000402522.1
TBC1D1


TBC1 (tre-2/USP6, BUB2, cdc16) domain family, member 1


chr14_-_70546897 0.455 ENST00000394330.2
ENST00000533541.1
ENST00000216568.7
SLC8A3


solute carrier family 8 (sodium/calcium exchanger), member 3


chr1_+_212782012 0.454 ENST00000341491.4
ENST00000366985.1
ATF3

activating transcription factor 3

chr11_-_47399942 0.421 ENST00000227163.4
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr7_-_113559104 0.420 ENST00000284601.3
PPP1R3A
protein phosphatase 1, regulatory subunit 3A
chr11_-_47400078 0.409 ENST00000378538.3
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr3_+_8543533 0.405 ENST00000454244.1
LMCD1
LIM and cysteine-rich domains 1
chr3_+_49057876 0.389 ENST00000326912.4
NDUFAF3
NADH dehydrogenase (ubiquinone) complex I, assembly factor 3
chr5_-_16509101 0.377 ENST00000399793.2
FAM134B
family with sequence similarity 134, member B
chr22_+_32340481 0.375 ENST00000397492.1
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr14_-_22005343 0.372 ENST00000327430.3
SALL2
spalt-like transcription factor 2
chr1_-_23751189 0.371 ENST00000374601.3
ENST00000450454.2
TCEA3

transcription elongation factor A (SII), 3

chr3_-_192445289 0.369 ENST00000430714.1
ENST00000418610.1
ENST00000448795.1
ENST00000445105.2
FGF12



fibroblast growth factor 12



chr5_-_150521192 0.366 ENST00000523714.1
ENST00000521749.1
ANXA6

annexin A6

chr14_-_94421923 0.354 ENST00000555507.1
ASB2
ankyrin repeat and SOCS box containing 2
chr22_+_32340447 0.349 ENST00000248975.5
YWHAH
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta
chr1_+_167063282 0.342 ENST00000361200.2
DUSP27
dual specificity phosphatase 27 (putative)
chr12_-_371994 0.330 ENST00000343164.4
ENST00000436453.1
ENST00000445055.2
ENST00000546319.1
SLC6A13



solute carrier family 6 (neurotransmitter transporter), member 13



chr3_+_138067521 0.328 ENST00000494949.1
MRAS
muscle RAS oncogene homolog
chrX_-_15332665 0.327 ENST00000537676.1
ENST00000344384.4
ASB11

ankyrin repeat and SOCS box containing 11

chr20_+_44657845 0.312 ENST00000243964.3
SLC12A5
solute carrier family 12 (potassium/chloride transporter), member 5
chr3_-_137834436 0.303 ENST00000327532.2
ENST00000467030.1
DZIP1L

DAZ interacting zinc finger protein 1-like

chr7_-_37488834 0.303 ENST00000310758.4
ELMO1
engulfment and cell motility 1
chr3_+_8543393 0.297 ENST00000157600.3
ENST00000415597.1
ENST00000535732.1
LMCD1


LIM and cysteine-rich domains 1


chr3_-_57326704 0.296 ENST00000487349.1
ENST00000389601.3
ASB14

ankyrin repeat and SOCS box containing 14

chr10_+_118350468 0.288 ENST00000358834.4
ENST00000528052.1
ENST00000442761.1
PNLIPRP1


pancreatic lipase-related protein 1


chr10_+_118350522 0.282 ENST00000530319.1
ENST00000527980.1
ENST00000471549.1
ENST00000534537.1
PNLIPRP1



pancreatic lipase-related protein 1



chr19_-_51220176 0.272 ENST00000359082.3
ENST00000293441.1
SHANK1

SH3 and multiple ankyrin repeat domains 1

chrX_-_142722897 0.271 ENST00000338017.4
SLITRK4
SLIT and NTRK-like family, member 4
chr10_-_69455873 0.267 ENST00000433211.2
CTNNA3
catenin (cadherin-associated protein), alpha 3
chr5_+_132009675 0.251 ENST00000231449.2
ENST00000350025.2
IL4

interleukin 4

chr1_-_116311402 0.244 ENST00000261448.5
CASQ2
calsequestrin 2 (cardiac muscle)
chr6_+_44194762 0.244 ENST00000371708.1
SLC29A1
solute carrier family 29 (equilibrative nucleoside transporter), member 1
chr3_+_54157480 0.225 ENST00000490478.1
CACNA2D3
calcium channel, voltage-dependent, alpha 2/delta subunit 3
chr12_-_45269430 0.224 ENST00000395487.2
NELL2
NEL-like 2 (chicken)
chr5_-_131347306 0.221 ENST00000296869.4
ENST00000379249.3
ENST00000379272.2
ENST00000379264.2
ACSL6



acyl-CoA synthetase long-chain family member 6



chr1_+_84630367 0.200 ENST00000370680.1
PRKACB
protein kinase, cAMP-dependent, catalytic, beta
chr7_-_105332084 0.199 ENST00000472195.1
ATXN7L1
ataxin 7-like 1
chr11_-_19223523 0.190 ENST00000265968.3
CSRP3
cysteine and glycine-rich protein 3 (cardiac LIM protein)
chr20_+_44035847 0.187 ENST00000372712.2
DBNDD2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr1_+_145413268 0.180 ENST00000421822.2
ENST00000336751.5
ENST00000497365.1
ENST00000475797.1
HFE2



hemochromatosis type 2 (juvenile)



chr18_-_3219847 0.171 ENST00000261606.7
MYOM1
myomesin 1
chr11_+_7597639 0.171 ENST00000533792.1
PPFIBP2
PTPRF interacting protein, binding protein 2 (liprin beta 2)
chr1_-_201391149 0.167 ENST00000555948.1
ENST00000556362.1
TNNI1

troponin I type 1 (skeletal, slow)

chr6_+_50061315 0.166 ENST00000415106.1
RP11-397G17.1
RP11-397G17.1
chr6_-_137314371 0.165 ENST00000432330.1
ENST00000418699.1
RP11-55K22.5

RP11-55K22.5

chr7_+_143013198 0.164 ENST00000343257.2
CLCN1
chloride channel, voltage-sensitive 1
chr12_-_5352315 0.159 ENST00000536518.1
RP11-319E16.1
RP11-319E16.1
chr1_+_156095951 0.159 ENST00000448611.2
ENST00000368297.1
LMNA

lamin A/C

chr5_+_155753745 0.149 ENST00000435422.3
ENST00000337851.4
ENST00000447401.1
SGCD


sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)


chr5_+_53751445 0.135 ENST00000302005.1
HSPB3
heat shock 27kDa protein 3
chr6_-_33160231 0.133 ENST00000395194.1
ENST00000457788.1
ENST00000341947.2
ENST00000357486.1
ENST00000374714.1
ENST00000374713.1
ENST00000395197.1
ENST00000374712.1
ENST00000361917.1
ENST00000374708.4
COL11A2









collagen, type XI, alpha 2









chr3_+_8543561 0.131 ENST00000397386.3
LMCD1
LIM and cysteine-rich domains 1
chr1_+_90098606 0.130 ENST00000370454.4
LRRC8C
leucine rich repeat containing 8 family, member C
chr5_-_131347583 0.129 ENST00000379255.1
ENST00000430403.1
ENST00000544770.1
ENST00000379246.1
ENST00000414078.1
ENST00000441995.1
ACSL6





acyl-CoA synthetase long-chain family member 6





chr15_+_100106244 0.128 ENST00000557942.1
MEF2A
myocyte enhancer factor 2A
chr7_+_30951461 0.126 ENST00000311813.4
AQP1
aquaporin 1 (Colton blood group)
chr9_-_85882145 0.125 ENST00000328788.1
FRMD3
FERM domain containing 3
chr3_+_138067666 0.117 ENST00000475711.1
ENST00000464896.1
MRAS

muscle RAS oncogene homolog

chr20_+_10199468 0.101 ENST00000254976.2
ENST00000304886.2
SNAP25

synaptosomal-associated protein, 25kDa

chr15_+_100106155 0.096 ENST00000557785.1
ENST00000558049.1
ENST00000449277.2
MEF2A


myocyte enhancer factor 2A


chr3_+_138067314 0.096 ENST00000423968.2
MRAS
muscle RAS oncogene homolog
chr11_+_1860200 0.094 ENST00000381911.1
TNNI2
troponin I type 2 (skeletal, fast)
chr11_+_1860682 0.094 ENST00000381906.1
TNNI2
troponin I type 2 (skeletal, fast)
chr15_+_100106126 0.093 ENST00000558812.1
ENST00000338042.6
MEF2A

myocyte enhancer factor 2A

chr20_+_11898507 0.087 ENST00000378226.2
BTBD3
BTB (POZ) domain containing 3
chr3_-_113897545 0.086 ENST00000467632.1
DRD3
dopamine receptor D3
chr8_-_95565673 0.085 ENST00000437199.1
ENST00000297591.5
ENST00000421249.2
KIAA1429


KIAA1429


chr18_-_3220106 0.083 ENST00000356443.4
ENST00000400569.3
MYOM1

myomesin 1

chr21_-_42219065 0.083 ENST00000400454.1
DSCAM
Down syndrome cell adhesion molecule
chr19_+_56713670 0.081 ENST00000534327.1
ZSCAN5C
zinc finger and SCAN domain containing 5C
chr8_+_76452097 0.075 ENST00000396423.2
HNF4G
hepatocyte nuclear factor 4, gamma
chr6_+_12007963 0.074 ENST00000607445.1
RP11-456H18.2
RP11-456H18.2
chr15_+_40531243 0.074 ENST00000558055.1
ENST00000455577.2
PAK6

p21 protein (Cdc42/Rac)-activated kinase 6

chr15_+_40531621 0.073 ENST00000560346.1
PAK6
p21 protein (Cdc42/Rac)-activated kinase 6
chr11_+_1860832 0.071 ENST00000252898.7
TNNI2
troponin I type 2 (skeletal, fast)
chr2_+_33661382 0.064 ENST00000402538.3
RASGRP3
RAS guanyl releasing protein 3 (calcium and DAG-regulated)
chr11_-_88796803 0.062 ENST00000418177.2
ENST00000455756.2
GRM5

glutamate receptor, metabotropic 5

chr5_-_131347501 0.060 ENST00000543479.1
ACSL6
acyl-CoA synthetase long-chain family member 6
chr17_-_5322786 0.056 ENST00000225696.4
NUP88
nucleoporin 88kDa
chr2_+_168043793 0.054 ENST00000409273.1
ENST00000409605.1
XIRP2

xin actin-binding repeat containing 2

chr1_-_150693318 0.051 ENST00000442853.1
ENST00000368995.4
ENST00000368993.2
ENST00000361824.2
ENST00000322343.7
HORMAD1




HORMA domain containing 1




chr21_-_33984456 0.051 ENST00000440966.1
ENST00000431216.1
ENST00000553001.1
C21orf59
AP000275.65

chromosome 21 open reading frame 59
Uncharacterized protein

chr12_+_25205568 0.044 ENST00000548766.1
ENST00000556887.1
LRMP

lymphoid-restricted membrane protein

chr1_+_92632542 0.042 ENST00000409154.4
ENST00000370378.4
KIAA1107

KIAA1107

chr12_+_25205666 0.042 ENST00000547044.1
LRMP
lymphoid-restricted membrane protein
chr2_-_157198860 0.041 ENST00000409572.1
NR4A2
nuclear receptor subfamily 4, group A, member 2
chr4_-_143226979 0.041 ENST00000514525.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr18_-_35145728 0.041 ENST00000361795.5
ENST00000603232.1
CELF4

CUGBP, Elav-like family member 4

chr12_+_25205446 0.040 ENST00000557489.1
ENST00000354454.3
ENST00000536173.1
LRMP


lymphoid-restricted membrane protein


chr7_-_16872932 0.040 ENST00000419572.2
ENST00000412973.1
AGR2

anterior gradient 2

chr10_-_96829246 0.038 ENST00000371270.3
ENST00000535898.1
ENST00000539050.1
CYP2C8


cytochrome P450, family 2, subfamily C, polypeptide 8


chr22_-_51017084 0.034 ENST00000360719.2
ENST00000457250.1
ENST00000440709.1
CPT1B


carnitine palmitoyltransferase 1B (muscle)


chr9_+_116327326 0.034 ENST00000342620.5
RGS3
regulator of G-protein signaling 3
chr2_-_190044480 0.032 ENST00000374866.3
COL5A2
collagen, type V, alpha 2
chr11_-_47400062 0.032 ENST00000533030.1
SPI1
spleen focus forming virus (SFFV) proviral integration oncogene
chr12_+_15699286 0.032 ENST00000442921.2
ENST00000542557.1
ENST00000445537.2
ENST00000544244.1
PTPRO



protein tyrosine phosphatase, receptor type, O



chr6_+_139094657 0.032 ENST00000332797.6
CCDC28A
coiled-coil domain containing 28A
chr18_-_35145981 0.031 ENST00000420428.2
ENST00000412753.1
CELF4

CUGBP, Elav-like family member 4

chr3_+_35683651 0.028 ENST00000187397.4
ARPP21
cAMP-regulated phosphoprotein, 21kDa
chr15_+_40226304 0.026 ENST00000559624.1
ENST00000382727.2
ENST00000263791.5
ENST00000560648.1
EIF2AK4



eukaryotic translation initiation factor 2 alpha kinase 4



chr4_-_143227088 0.018 ENST00000511838.1
INPP4B
inositol polyphosphate-4-phosphatase, type II, 105kDa
chr16_-_88717482 0.017 ENST00000261623.3
CYBA
cytochrome b-245, alpha polypeptide
chr10_-_31146615 0.016 ENST00000444692.2
ZNF438
zinc finger protein 438
chr15_+_68346501 0.015 ENST00000249636.6
PIAS1
protein inhibitor of activated STAT, 1
chr10_+_71561704 0.014 ENST00000520267.1
COL13A1
collagen, type XIII, alpha 1
chr2_-_165424973 0.010 ENST00000543549.1
GRB14
growth factor receptor-bound protein 14
chr9_-_74980113 0.010 ENST00000376962.5
ENST00000376960.4
ENST00000237937.3
ZFAND5


zinc finger, AN1-type domain 5


chr16_+_12059050 0.006 ENST00000396495.3
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr14_+_56046990 0.006 ENST00000438792.2
ENST00000395314.3
ENST00000395308.1
KTN1


kinectin 1 (kinesin receptor)


chr3_-_176914238 0.006 ENST00000430069.1
ENST00000428970.1
TBL1XR1

transducin (beta)-like 1 X-linked receptor 1

chr16_+_12058961 0.005 ENST00000053243.1
TNFRSF17
tumor necrosis factor receptor superfamily, member 17
chr1_+_156096336 0.003 ENST00000504687.1
ENST00000473598.2
LMNA

lamin A/C

chr22_-_51016846 0.003 ENST00000312108.7
ENST00000395650.2
CPT1B

carnitine palmitoyltransferase 1B (muscle)

chr6_-_123957942 0.001 ENST00000398178.3
TRDN
triadin
chr2_+_88367299 0.000 ENST00000419482.2
ENST00000444564.2
SMYD1

SET and MYND domain containing 1

chr17_+_20059302 0.000 ENST00000395530.2
SPECC1
sperm antigen with calponin homology and coiled-coil domains 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.2 0.9 GO:0044027 hypermethylation of CpG island(GO:0044027)
0.2 0.5 GO:0000117 regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117)
0.2 0.5 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.2 0.5 GO:0061394 regulation of transcription from RNA polymerase II promoter in response to arsenic-containing substance(GO:0061394)
0.1 1.2 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.5 GO:0032972 diaphragm contraction(GO:0002086) regulation of muscle filament sliding speed(GO:0032972)
0.1 0.4 GO:0071288 cellular response to mercury ion(GO:0071288)
0.1 0.3 GO:0050894 determination of affect(GO:0050894)
0.1 0.8 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.5 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.4 GO:1905150 regulation of voltage-gated sodium channel activity(GO:1905150)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.3 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005) ERK5 cascade(GO:0070375)
0.0 0.9 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.5 GO:2000291 regulation of myoblast proliferation(GO:2000291)
0.0 0.2 GO:0071313 cellular response to caffeine(GO:0071313)
0.0 0.8 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.0 0.2 GO:0035105 sterol regulatory element binding protein import into nucleus(GO:0035105)
0.0 0.6 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.2 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.7 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.3 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 1.2 GO:0046710 GDP metabolic process(GO:0046710)
0.0 0.1 GO:0060023 soft palate development(GO:0060023)
0.0 0.1 GO:0032416 negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883)
0.0 0.1 GO:0007206 phospholipase C-activating G-protein coupled glutamate receptor signaling pathway(GO:0007206)
0.0 0.3 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 1.8 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 2.1 GO:0061045 negative regulation of wound healing(GO:0061045)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138) meiotic recombination checkpoint(GO:0051598)
0.0 0.2 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.8 GO:0007019 microtubule depolymerization(GO:0007019)
0.0 0.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.0 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.0 0.4 GO:0035338 long-chain fatty-acyl-CoA biosynthetic process(GO:0035338)
0.0 0.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.1 GO:0080009 mRNA methylation(GO:0080009)
0.0 0.1 GO:0097338 response to clozapine(GO:0097338)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.0 GO:0036058 filtration diaphragm assembly(GO:0036058) slit diaphragm assembly(GO:0036060)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1990622 CHOP-ATF3 complex(GO:1990622)
0.1 0.5 GO:1990584 cardiac Troponin complex(GO:1990584)
0.1 0.8 GO:0097512 cardiac myofibril(GO:0097512)
0.1 1.6 GO:0032982 myosin filament(GO:0032982)
0.0 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0020005 symbiont-containing vacuole(GO:0020003) symbiont-containing vacuole membrane(GO:0020005)
0.0 0.5 GO:0032039 integrator complex(GO:0032039)
0.0 1.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0005916 fascia adherens(GO:0005916)
0.0 0.5 GO:0005859 muscle myosin complex(GO:0005859)
0.0 0.4 GO:0005861 troponin complex(GO:0005861)
0.0 0.7 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0036396 MIS complex(GO:0036396) mRNA editing complex(GO:0045293)
0.0 0.4 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.1 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.0 0.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.5 GO:0097546 ciliary base(GO:0097546)
0.0 0.7 GO:0014704 intercalated disc(GO:0014704)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 0.5 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.7 GO:0051373 FATZ binding(GO:0051373)
0.1 0.3 GO:0031877 somatostatin receptor binding(GO:0031877)
0.1 0.3 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 0.3 GO:0005136 interleukin-4 receptor binding(GO:0005136)
0.1 0.9 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.5 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.1 1.6 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.1 0.3 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 0.8 GO:0031014 troponin T binding(GO:0031014)
0.1 0.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.1 GO:0035379 carbon dioxide transmembrane transporter activity(GO:0035379)
0.0 0.2 GO:0031433 telethonin binding(GO:0031433)
0.0 0.8 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.3 GO:0086083 cell adhesive protein binding involved in bundle of His cell-Purkinje myocyte communication(GO:0086083)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 1.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.6 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.6 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0030020 extracellular matrix structural constituent conferring tensile strength(GO:0030020)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591)
0.0 0.1 GO:0042835 BRE binding(GO:0042835)

Gene overrepresentation in C2:CP category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID_THROMBIN_PAR4_PATHWAY PAR4-mediated thrombin signaling events
0.0 1.0 PID_INSULIN_GLUCOSE_PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in C2:CP:REACTOME category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.2 REACTOME_STRIATED_MUSCLE_CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.4 REACTOME_SYNTHESIS_OF_VERY_LONG_CHAIN_FATTY_ACYL_COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.5 REACTOME_PLATELET_CALCIUM_HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.5 REACTOME_ACTIVATION_OF_GENES_BY_ATF4 Genes involved in Activation of Genes by ATF4