Motif ID: MEIS1
Z-value: 0.557
Transcription factors associated with MEIS1:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
MEIS1 | ENSG00000143995.15 | MEIS1 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
MEIS1 | hg19_v2_chr2_+_66662690_66662711 | -0.46 | 2.4e-02 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.1 | GO:0060557 | positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559) |
0.3 | 1.6 | GO:0003322 | pancreatic A cell development(GO:0003322) |
0.2 | 0.7 | GO:0033242 | regulation of cellular amine catabolic process(GO:0033241) negative regulation of cellular amine catabolic process(GO:0033242) negative regulation of the force of heart contraction(GO:0098736) regulation of arginine catabolic process(GO:1900081) negative regulation of arginine catabolic process(GO:1900082) regulation of citrulline biosynthetic process(GO:1903248) negative regulation of citrulline biosynthetic process(GO:1903249) negative regulation of cellular amino acid biosynthetic process(GO:2000283) |
0.2 | 0.9 | GO:0061743 | motor learning(GO:0061743) |
0.2 | 1.3 | GO:1900623 | regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625) |
0.2 | 0.7 | GO:0051122 | hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122) |
0.2 | 0.5 | GO:0071109 | superior temporal gyrus development(GO:0071109) |
0.2 | 0.8 | GO:1902378 | vestibulocochlear nerve structural organization(GO:0021649) positive regulation of cytokine activity(GO:0060301) ganglion morphogenesis(GO:0061552) VEGF-activated neuropilin signaling pathway involved in axon guidance(GO:1902378) dorsal root ganglion morphogenesis(GO:1904835) otic placode development(GO:1905040) |
0.1 | 0.4 | GO:0032877 | positive regulation of DNA endoreduplication(GO:0032877) |
0.1 | 1.3 | GO:2001300 | lipoxin metabolic process(GO:2001300) |
0.1 | 1.4 | GO:0035583 | sequestering of TGFbeta in extracellular matrix(GO:0035583) |
0.1 | 0.9 | GO:0021842 | directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842) |
0.1 | 1.0 | GO:0006452 | translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905) |
0.1 | 0.5 | GO:0090362 | positive regulation of platelet-derived growth factor production(GO:0090362) |
0.1 | 0.4 | GO:0018057 | peptidyl-lysine oxidation(GO:0018057) |
0.1 | 0.4 | GO:0031660 | regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to DDT(GO:0046680) histone H3-S10 phosphorylation involved in chromosome condensation(GO:2000775) |
0.1 | 0.5 | GO:1904448 | negative regulation of gamma-aminobutyric acid secretion(GO:0014053) aspartate secretion(GO:0061528) regulation of aspartate secretion(GO:1904448) positive regulation of aspartate secretion(GO:1904450) |
0.1 | 0.6 | GO:0018101 | protein citrullination(GO:0018101) histone citrullination(GO:0036414) |
0.1 | 0.3 | GO:0043311 | positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568) |
0.1 | 0.4 | GO:0010982 | regulation of high-density lipoprotein particle clearance(GO:0010982) |
0.1 | 0.5 | GO:0033078 | extrathymic T cell differentiation(GO:0033078) |
0.1 | 0.8 | GO:0009441 | glycolate metabolic process(GO:0009441) |
0.1 | 0.6 | GO:0061502 | early endosome to recycling endosome transport(GO:0061502) |
0.1 | 0.3 | GO:0098746 | fast, calcium ion-dependent exocytosis of neurotransmitter(GO:0098746) |
0.1 | 0.3 | GO:0070563 | negative regulation of vitamin D receptor signaling pathway(GO:0070563) |
0.1 | 0.6 | GO:0006982 | response to lipid hydroperoxide(GO:0006982) |
0.1 | 0.3 | GO:2000866 | positive regulation of estrogen secretion(GO:2000863) positive regulation of estradiol secretion(GO:2000866) |
0.1 | 0.3 | GO:0002728 | negative regulation of natural killer cell cytokine production(GO:0002728) |
0.1 | 0.3 | GO:0045658 | regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659) |
0.1 | 0.5 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
0.1 | 0.5 | GO:0051012 | microtubule sliding(GO:0051012) |
0.1 | 0.5 | GO:0060528 | secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528) |
0.1 | 0.6 | GO:0016128 | phytosteroid metabolic process(GO:0016128) phytosteroid biosynthetic process(GO:0016129) |
0.1 | 0.7 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
0.1 | 1.1 | GO:1904322 | response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322) |
0.1 | 0.1 | GO:2000329 | negative regulation of T-helper 17 cell lineage commitment(GO:2000329) |
0.1 | 0.2 | GO:0002384 | hepatic immune response(GO:0002384) |
0.1 | 0.6 | GO:0061588 | calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylserine scrambling(GO:0061589) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591) |
0.1 | 0.3 | GO:1903377 | negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377) |
0.1 | 0.4 | GO:1904338 | regulation of dopaminergic neuron differentiation(GO:1904338) |
0.1 | 0.4 | GO:0046340 | diacylglycerol catabolic process(GO:0046340) |
0.1 | 0.2 | GO:0036333 | hepatocyte homeostasis(GO:0036333) response to tetrachloromethane(GO:1904772) |
0.1 | 0.3 | GO:0046035 | CMP salvage(GO:0006238) CMP biosynthetic process(GO:0009224) CMP metabolic process(GO:0046035) |
0.1 | 0.2 | GO:0019417 | sulfur oxidation(GO:0019417) |
0.1 | 0.2 | GO:0000412 | histone peptidyl-prolyl isomerization(GO:0000412) |
0.1 | 0.3 | GO:0032914 | positive regulation of transforming growth factor beta1 production(GO:0032914) |
0.1 | 0.2 | GO:1903526 | negative regulation of membrane tubulation(GO:1903526) |
0.1 | 0.2 | GO:2000646 | positive regulation of receptor catabolic process(GO:2000646) |
0.1 | 0.5 | GO:0060842 | arterial endothelial cell differentiation(GO:0060842) |
0.1 | 0.3 | GO:0090131 | mesenchyme migration(GO:0090131) |
0.1 | 0.1 | GO:1903800 | regulation of production of small RNA involved in gene silencing by RNA(GO:0070920) regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903798) positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800) |
0.1 | 0.3 | GO:0061767 | negative regulation of lung blood pressure(GO:0061767) |
0.1 | 0.4 | GO:0060744 | thelarche(GO:0042695) mammary gland branching involved in thelarche(GO:0060744) |
0.1 | 0.3 | GO:1902728 | positive regulation of skeletal muscle cell proliferation(GO:0014858) mineralocorticoid receptor signaling pathway(GO:0031959) positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728) |
0.1 | 0.4 | GO:0003383 | apical constriction(GO:0003383) |
0.1 | 0.5 | GO:0002329 | pre-B cell differentiation(GO:0002329) |
0.1 | 0.3 | GO:0021797 | forebrain anterior/posterior pattern specification(GO:0021797) |
0.1 | 0.7 | GO:0010891 | negative regulation of sequestering of triglyceride(GO:0010891) |
0.1 | 0.2 | GO:0035359 | negative regulation of triglyceride catabolic process(GO:0010897) negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) |
0.1 | 0.3 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
0.1 | 0.2 | GO:1900073 | regulation of neuromuscular synaptic transmission(GO:1900073) positive regulation of neuromuscular synaptic transmission(GO:1900075) |
0.1 | 0.2 | GO:1900106 | hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106) |
0.1 | 0.2 | GO:0051673 | membrane disruption in other organism(GO:0051673) |
0.1 | 0.3 | GO:1901908 | diadenosine polyphosphate catabolic process(GO:0015961) diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911) |
0.0 | 0.1 | GO:0050902 | leukocyte adhesive activation(GO:0050902) |
0.0 | 0.2 | GO:0090158 | endoplasmic reticulum membrane organization(GO:0090158) |
0.0 | 0.3 | GO:0032468 | Golgi calcium ion homeostasis(GO:0032468) |
0.0 | 0.1 | GO:1901350 | cell-cell signaling involved in cell-cell junction organization(GO:1901350) |
0.0 | 0.1 | GO:0048213 | Golgi vesicle prefusion complex stabilization(GO:0048213) |
0.0 | 0.5 | GO:0038044 | transforming growth factor-beta secretion(GO:0038044) |
0.0 | 0.3 | GO:0030035 | microspike assembly(GO:0030035) |
0.0 | 0.4 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
0.0 | 0.4 | GO:0014051 | gamma-aminobutyric acid secretion(GO:0014051) |
0.0 | 0.2 | GO:0032641 | lymphotoxin A production(GO:0032641) lymphotoxin A biosynthetic process(GO:0042109) |
0.0 | 0.1 | GO:0090149 | mitochondrial membrane fission(GO:0090149) |
0.0 | 0.1 | GO:0009051 | pentose-phosphate shunt, oxidative branch(GO:0009051) |
0.0 | 0.2 | GO:0032416 | negative regulation of sodium:proton antiporter activity(GO:0032416) musculoskeletal movement, spinal reflex action(GO:0050883) |
0.0 | 0.4 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
0.0 | 0.1 | GO:0019085 | early viral transcription(GO:0019085) |
0.0 | 0.1 | GO:0071158 | positive regulation of cell cycle arrest(GO:0071158) |
0.0 | 0.1 | GO:0021569 | rhombomere 3 development(GO:0021569) |
0.0 | 0.2 | GO:0071484 | response to high light intensity(GO:0009644) cellular response to light intensity(GO:0071484) |
0.0 | 0.1 | GO:0021718 | superior olivary nucleus development(GO:0021718) superior olivary nucleus maturation(GO:0021722) |
0.0 | 0.6 | GO:0098828 | positive regulation of inhibitory postsynaptic potential(GO:0097151) modulation of inhibitory postsynaptic potential(GO:0098828) |
0.0 | 0.2 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
0.0 | 0.2 | GO:1901804 | beta-glucoside metabolic process(GO:1901804) beta-glucoside catabolic process(GO:1901805) positive regulation of neuronal action potential(GO:1904457) |
0.0 | 0.1 | GO:0044179 | hemolysis by symbiont of host erythrocytes(GO:0019836) hemolysis in other organism(GO:0044179) hemolysis in other organism involved in symbiotic interaction(GO:0052331) |
0.0 | 0.1 | GO:0042450 | arginine biosynthetic process via ornithine(GO:0042450) response to biotin(GO:0070781) |
0.0 | 0.1 | GO:0051685 | maintenance of ER location(GO:0051685) |
0.0 | 0.2 | GO:0097498 | endothelial tube lumen extension(GO:0097498) |
0.0 | 0.3 | GO:1903385 | regulation of homophilic cell adhesion(GO:1903385) |
0.0 | 0.1 | GO:0000117 | regulation of transcription involved in G2/M transition of mitotic cell cycle(GO:0000117) |
0.0 | 0.2 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.0 | 0.2 | GO:0006436 | tryptophanyl-tRNA aminoacylation(GO:0006436) |
0.0 | 0.3 | GO:0051295 | establishment of meiotic spindle localization(GO:0051295) |
0.0 | 0.1 | GO:1902044 | regulation of Fas signaling pathway(GO:1902044) |
0.0 | 0.1 | GO:0071105 | response to interleukin-11(GO:0071105) |
0.0 | 0.5 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
0.0 | 0.3 | GO:0001661 | conditioned taste aversion(GO:0001661) |
0.0 | 0.1 | GO:0038043 | interleukin-5-mediated signaling pathway(GO:0038043) |
0.0 | 0.8 | GO:0035589 | G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589) |
0.0 | 4.7 | GO:0070268 | cornification(GO:0070268) |
0.0 | 0.1 | GO:0045360 | regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362) |
0.0 | 0.1 | GO:0044111 | development involved in symbiotic interaction(GO:0044111) |
0.0 | 0.1 | GO:0060061 | Spemann organizer formation(GO:0060061) |
0.0 | 0.1 | GO:0002528 | regulation of vascular permeability involved in acute inflammatory response(GO:0002528) |
0.0 | 0.1 | GO:0035526 | retrograde transport, plasma membrane to Golgi(GO:0035526) |
0.0 | 0.2 | GO:0002767 | immune response-inhibiting cell surface receptor signaling pathway(GO:0002767) |
0.0 | 0.2 | GO:0071926 | endocannabinoid signaling pathway(GO:0071926) regulation of endocannabinoid signaling pathway(GO:2000124) |
0.0 | 0.8 | GO:1903861 | positive regulation of dendrite extension(GO:1903861) |
0.0 | 0.2 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
0.0 | 0.1 | GO:0017198 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
0.0 | 0.4 | GO:0006657 | CDP-choline pathway(GO:0006657) |
0.0 | 0.2 | GO:0046826 | negative regulation of protein export from nucleus(GO:0046826) |
0.0 | 0.1 | GO:0046533 | negative regulation of photoreceptor cell differentiation(GO:0046533) regulation of retinal cell programmed cell death(GO:0046668) |
0.0 | 0.1 | GO:0048867 | ganglion mother cell fate determination(GO:0007402) stem cell fate determination(GO:0048867) |
0.0 | 0.7 | GO:0035646 | endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757) |
0.0 | 0.1 | GO:1902938 | regulation of intracellular calcium activated chloride channel activity(GO:1902938) |
0.0 | 0.1 | GO:0035964 | COPI-coated vesicle budding(GO:0035964) Golgi transport vesicle coating(GO:0048200) COPI coating of Golgi vesicle(GO:0048205) |
0.0 | 0.3 | GO:0051694 | pointed-end actin filament capping(GO:0051694) |
0.0 | 0.1 | GO:0051026 | chiasma assembly(GO:0051026) |
0.0 | 0.1 | GO:0033274 | response to vitamin B2(GO:0033274) heterochromatin maintenance(GO:0070829) |
0.0 | 0.2 | GO:0046985 | positive regulation of hemoglobin biosynthetic process(GO:0046985) |
0.0 | 0.1 | GO:0006700 | C21-steroid hormone biosynthetic process(GO:0006700) |
0.0 | 0.2 | GO:0031914 | negative regulation of synaptic plasticity(GO:0031914) |
0.0 | 0.1 | GO:0014876 | response to injury involved in regulation of muscle adaptation(GO:0014876) |
0.0 | 0.1 | GO:1990502 | dense core granule maturation(GO:1990502) |
0.0 | 0.2 | GO:0045039 | protein import into mitochondrial inner membrane(GO:0045039) |
0.0 | 0.2 | GO:0014718 | positive regulation of satellite cell activation involved in skeletal muscle regeneration(GO:0014718) |
0.0 | 0.0 | GO:0072425 | signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) |
0.0 | 0.1 | GO:0038155 | interleukin-23-mediated signaling pathway(GO:0038155) |
0.0 | 0.2 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
0.0 | 0.1 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
0.0 | 0.2 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
0.0 | 0.2 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
0.0 | 0.3 | GO:0035372 | protein localization to microtubule(GO:0035372) |
0.0 | 0.1 | GO:1902896 | terminal web assembly(GO:1902896) |
0.0 | 0.1 | GO:0014835 | myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) |
0.0 | 0.2 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
0.0 | 0.1 | GO:0006663 | platelet activating factor biosynthetic process(GO:0006663) |
0.0 | 0.1 | GO:0060373 | regulation of ventricular cardiac muscle cell membrane depolarization(GO:0060373) |
0.0 | 0.2 | GO:0009730 | detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594) |
0.0 | 0.1 | GO:1905205 | positive regulation of connective tissue replacement(GO:1905205) |
0.0 | 0.0 | GO:0021764 | amygdala development(GO:0021764) |
0.0 | 0.1 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
0.0 | 0.0 | GO:0046666 | retinal cell programmed cell death(GO:0046666) |
0.0 | 0.2 | GO:0030091 | protein repair(GO:0030091) |
0.0 | 0.2 | GO:0007256 | activation of JNKK activity(GO:0007256) |
0.0 | 0.4 | GO:0000183 | chromatin silencing at rDNA(GO:0000183) |
0.0 | 0.1 | GO:0097106 | postsynaptic density organization(GO:0097106) |
0.0 | 0.1 | GO:0021937 | cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937) |
0.0 | 0.4 | GO:0002227 | innate immune response in mucosa(GO:0002227) |
0.0 | 0.0 | GO:2001027 | negative regulation of endothelial cell chemotaxis(GO:2001027) |
0.0 | 0.2 | GO:0045852 | pH elevation(GO:0045852) intracellular pH elevation(GO:0051454) |
0.0 | 0.1 | GO:0035166 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) post-embryonic hemopoiesis(GO:0035166) |
0.0 | 1.0 | GO:0043029 | T cell homeostasis(GO:0043029) |
0.0 | 0.3 | GO:0034393 | positive regulation of smooth muscle cell apoptotic process(GO:0034393) |
0.0 | 0.2 | GO:0009629 | response to gravity(GO:0009629) |
0.0 | 0.9 | GO:0000188 | inactivation of MAPK activity(GO:0000188) |
0.0 | 0.3 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
0.0 | 0.4 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
0.0 | 0.1 | GO:0070458 | cellular detoxification of nitrogen compound(GO:0070458) |
0.0 | 0.7 | GO:1903846 | positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846) |
0.0 | 0.1 | GO:1903697 | negative regulation of microvillus assembly(GO:1903697) |
0.0 | 0.1 | GO:0035965 | cardiolipin acyl-chain remodeling(GO:0035965) |
0.0 | 0.1 | GO:0048250 | mitochondrial iron ion transport(GO:0048250) |
0.0 | 0.1 | GO:0042866 | pyruvate biosynthetic process(GO:0042866) |
0.0 | 0.1 | GO:0046900 | tetrahydrofolylpolyglutamate metabolic process(GO:0046900) |
0.0 | 0.1 | GO:0008218 | bioluminescence(GO:0008218) |
0.0 | 0.1 | GO:0035616 | histone H2B conserved C-terminal lysine deubiquitination(GO:0035616) |
0.0 | 0.2 | GO:0086069 | bundle of His cell to Purkinje myocyte communication(GO:0086069) |
0.0 | 0.2 | GO:0097264 | self proteolysis(GO:0097264) |
0.0 | 0.0 | GO:0060474 | positive regulation of sperm motility involved in capacitation(GO:0060474) |
0.0 | 0.1 | GO:0045204 | MAPK export from nucleus(GO:0045204) |
0.0 | 0.1 | GO:0043686 | co-translational protein modification(GO:0043686) |
0.0 | 0.1 | GO:1902530 | regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530) |
0.0 | 0.5 | GO:0051290 | protein heterotetramerization(GO:0051290) |
0.0 | 0.1 | GO:1990180 | mitochondrial tRNA 3'-end processing(GO:1990180) |
0.0 | 0.3 | GO:0032802 | low-density lipoprotein particle receptor catabolic process(GO:0032802) |
0.0 | 0.4 | GO:0002244 | hematopoietic progenitor cell differentiation(GO:0002244) |
0.0 | 0.3 | GO:0010867 | positive regulation of triglyceride biosynthetic process(GO:0010867) |
0.0 | 0.1 | GO:0006665 | sphingolipid metabolic process(GO:0006665) |
0.0 | 0.1 | GO:0021798 | forebrain dorsal/ventral pattern formation(GO:0021798) |
0.0 | 0.1 | GO:0061056 | sclerotome development(GO:0061056) |
0.0 | 0.5 | GO:0030207 | chondroitin sulfate catabolic process(GO:0030207) |
0.0 | 0.1 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) |
0.0 | 0.1 | GO:0051005 | negative regulation of lipoprotein lipase activity(GO:0051005) |
0.0 | 0.2 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
0.0 | 0.1 | GO:1902474 | positive regulation of protein localization to synapse(GO:1902474) |
0.0 | 0.2 | GO:0042262 | DNA protection(GO:0042262) |
0.0 | 0.1 | GO:0045586 | regulation of gamma-delta T cell differentiation(GO:0045586) |
0.0 | 0.1 | GO:2000643 | positive regulation of early endosome to late endosome transport(GO:2000643) |
0.0 | 0.1 | GO:0060010 | Sertoli cell fate commitment(GO:0060010) |
0.0 | 0.1 | GO:0001545 | primary ovarian follicle growth(GO:0001545) |
0.0 | 0.1 | GO:1903715 | regulation of aerobic respiration(GO:1903715) |
0.0 | 0.1 | GO:0016554 | cytidine to uridine editing(GO:0016554) |
0.0 | 0.0 | GO:0061386 | closure of optic fissure(GO:0061386) |
0.0 | 0.1 | GO:0022614 | membrane to membrane docking(GO:0022614) |
0.0 | 0.2 | GO:0051451 | myoblast migration(GO:0051451) |
0.0 | 0.1 | GO:0051106 | positive regulation of DNA ligation(GO:0051106) |
0.0 | 0.5 | GO:0002260 | lymphocyte homeostasis(GO:0002260) |
0.0 | 0.1 | GO:1903644 | regulation of chaperone-mediated protein folding(GO:1903644) |
0.0 | 0.1 | GO:0016127 | cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127) |
0.0 | 0.7 | GO:0003254 | regulation of membrane depolarization(GO:0003254) |
0.0 | 0.1 | GO:0006172 | ADP biosynthetic process(GO:0006172) |
0.0 | 0.6 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
0.0 | 0.1 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
0.0 | 0.1 | GO:0001890 | placenta development(GO:0001890) |
0.0 | 0.1 | GO:0090080 | positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080) |
0.0 | 0.2 | GO:0070070 | proton-transporting V-type ATPase complex assembly(GO:0070070) vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
0.0 | 0.0 | GO:0035482 | gastric motility(GO:0035482) gastric emptying(GO:0035483) |
0.0 | 0.0 | GO:0016344 | meiotic chromosome movement towards spindle pole(GO:0016344) |
0.0 | 0.1 | GO:0048703 | embryonic viscerocranium morphogenesis(GO:0048703) |
0.0 | 0.1 | GO:0021562 | vestibulocochlear nerve development(GO:0021562) |
0.0 | 0.2 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
0.0 | 0.1 | GO:1903336 | negative regulation of vacuolar transport(GO:1903336) |
0.0 | 0.4 | GO:0044030 | regulation of DNA methylation(GO:0044030) |
0.0 | 0.4 | GO:0042730 | fibrinolysis(GO:0042730) |
0.0 | 0.2 | GO:0002091 | negative regulation of receptor internalization(GO:0002091) |
0.0 | 0.1 | GO:0060012 | synaptic transmission, glycinergic(GO:0060012) |
0.0 | 0.1 | GO:0006311 | meiotic gene conversion(GO:0006311) |
0.0 | 0.1 | GO:0031340 | positive regulation of vesicle fusion(GO:0031340) |
0.0 | 0.1 | GO:0035546 | interferon-beta secretion(GO:0035546) regulation of interferon-beta secretion(GO:0035547) positive regulation of interferon-beta secretion(GO:0035549) |
0.0 | 0.1 | GO:2000334 | blood microparticle formation(GO:0072564) regulation of blood microparticle formation(GO:2000332) positive regulation of blood microparticle formation(GO:2000334) |
0.0 | 0.1 | GO:0034638 | phosphatidylcholine catabolic process(GO:0034638) |
0.0 | 0.1 | GO:0007525 | somatic muscle development(GO:0007525) |
0.0 | 0.1 | GO:2000639 | regulation of SREBP signaling pathway(GO:2000638) negative regulation of SREBP signaling pathway(GO:2000639) |
0.0 | 0.0 | GO:0051541 | elastin metabolic process(GO:0051541) |
0.0 | 0.2 | GO:0003376 | sphingosine-1-phosphate signaling pathway(GO:0003376) sphingolipid mediated signaling pathway(GO:0090520) |
0.0 | 0.0 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
0.0 | 0.0 | GO:0043376 | regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) |
0.0 | 0.1 | GO:0050957 | equilibrioception(GO:0050957) |
0.0 | 0.2 | GO:0002097 | tRNA wobble base modification(GO:0002097) |
0.0 | 0.2 | GO:0036066 | protein O-linked fucosylation(GO:0036066) |
0.0 | 0.1 | GO:0030046 | parallel actin filament bundle assembly(GO:0030046) |
0.0 | 0.5 | GO:0050819 | negative regulation of coagulation(GO:0050819) |
0.0 | 0.1 | GO:0010866 | regulation of triglyceride biosynthetic process(GO:0010866) |
0.0 | 0.2 | GO:0000338 | protein deneddylation(GO:0000338) |
0.0 | 0.1 | GO:0035845 | photoreceptor cell outer segment organization(GO:0035845) |
0.0 | 0.0 | GO:0016185 | synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) neurotransmitter receptor internalization(GO:0099590) |
0.0 | 0.1 | GO:0051895 | negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392) |
0.0 | 0.2 | GO:0035414 | negative regulation of catenin import into nucleus(GO:0035414) |
0.0 | 0.1 | GO:0007173 | epidermal growth factor receptor signaling pathway(GO:0007173) |
0.0 | 0.1 | GO:0045792 | negative regulation of cell size(GO:0045792) |
0.0 | 0.1 | GO:1900239 | phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239) |
0.0 | 0.0 | GO:0060392 | negative regulation of SMAD protein import into nucleus(GO:0060392) |
0.0 | 0.1 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
0.0 | 0.3 | GO:0045932 | negative regulation of muscle contraction(GO:0045932) |
0.0 | 0.1 | GO:0048664 | neuron fate determination(GO:0048664) |
0.0 | 0.2 | GO:0007095 | mitotic G2 DNA damage checkpoint(GO:0007095) |
0.0 | 0.1 | GO:0031284 | positive regulation of guanylate cyclase activity(GO:0031284) |
0.0 | 0.0 | GO:2000504 | positive regulation of blood vessel remodeling(GO:2000504) |
0.0 | 0.0 | GO:0051490 | negative regulation of filopodium assembly(GO:0051490) |
0.0 | 0.1 | GO:0045793 | positive regulation of cell size(GO:0045793) |
0.0 | 0.2 | GO:0030214 | hyaluronan catabolic process(GO:0030214) |
0.0 | 0.1 | GO:0002200 | somatic diversification of immune receptors(GO:0002200) |
0.0 | 0.4 | GO:0022400 | regulation of rhodopsin mediated signaling pathway(GO:0022400) |
0.0 | 1.0 | GO:0000731 | DNA synthesis involved in DNA repair(GO:0000731) |
0.0 | 0.3 | GO:0001556 | oocyte maturation(GO:0001556) |
0.0 | 0.1 | GO:1901098 | positive regulation of autophagosome maturation(GO:1901098) |
0.0 | 0.1 | GO:0032526 | response to retinoic acid(GO:0032526) |
0.0 | 0.0 | GO:0044501 | modulation of signal transduction in other organism(GO:0044501) modulation by symbiont of host signal transduction pathway(GO:0052027) modulation of signal transduction in other organism involved in symbiotic interaction(GO:0052250) modulation by symbiont of host I-kappaB kinase/NF-kappaB cascade(GO:0085032) |
0.0 | 0.0 | GO:2000296 | negative regulation of hydrogen peroxide catabolic process(GO:2000296) |
0.0 | 0.4 | GO:1903959 | regulation of anion transmembrane transport(GO:1903959) |
0.0 | 0.1 | GO:0008090 | retrograde axonal transport(GO:0008090) |
0.0 | 0.1 | GO:0035413 | positive regulation of catenin import into nucleus(GO:0035413) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.4 | GO:0035692 | macrophage migration inhibitory factor receptor complex(GO:0035692) |
0.2 | 0.5 | GO:0034685 | integrin alphav-beta6 complex(GO:0034685) |
0.1 | 0.5 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.1 | 0.5 | GO:0032144 | 4-aminobutyrate transaminase complex(GO:0032144) |
0.1 | 0.4 | GO:0033186 | CAF-1 complex(GO:0033186) |
0.1 | 0.5 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
0.1 | 1.0 | GO:0097443 | sorting endosome(GO:0097443) |
0.1 | 0.3 | GO:0031523 | Myb complex(GO:0031523) |
0.1 | 0.3 | GO:0071595 | Nem1-Spo7 phosphatase complex(GO:0071595) |
0.1 | 0.4 | GO:0097125 | cyclin B1-CDK1 complex(GO:0097125) |
0.1 | 0.4 | GO:0033553 | rDNA heterochromatin(GO:0033553) |
0.1 | 0.3 | GO:0030934 | anchoring collagen complex(GO:0030934) |
0.1 | 0.2 | GO:0042721 | mitochondrial inner membrane protein insertion complex(GO:0042721) |
0.1 | 0.3 | GO:0060200 | clathrin-sculpted acetylcholine transport vesicle(GO:0060200) clathrin-sculpted acetylcholine transport vesicle membrane(GO:0060201) |
0.1 | 0.7 | GO:0005642 | annulate lamellae(GO:0005642) |
0.1 | 1.5 | GO:0043205 | microfibril(GO:0001527) fibril(GO:0043205) |
0.1 | 0.2 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
0.1 | 0.4 | GO:0031466 | Cul5-RING ubiquitin ligase complex(GO:0031466) |
0.1 | 0.2 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
0.0 | 0.3 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
0.0 | 0.1 | GO:0097058 | CRLF-CLCF1 complex(GO:0097058) |
0.0 | 1.2 | GO:0001891 | phagocytic cup(GO:0001891) |
0.0 | 0.7 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.0 | 1.1 | GO:0008074 | guanylate cyclase complex, soluble(GO:0008074) |
0.0 | 0.3 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
0.0 | 0.2 | GO:0044614 | nuclear pore cytoplasmic filaments(GO:0044614) |
0.0 | 1.5 | GO:0030673 | axolemma(GO:0030673) |
0.0 | 0.0 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.2 | GO:0035867 | alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
0.0 | 0.6 | GO:0031089 | platelet dense granule lumen(GO:0031089) |
0.0 | 0.3 | GO:0035976 | AP1 complex(GO:0035976) |
0.0 | 0.3 | GO:0071144 | SMAD2-SMAD3 protein complex(GO:0071144) |
0.0 | 2.2 | GO:0001533 | cornified envelope(GO:0001533) |
0.0 | 0.2 | GO:0005826 | actomyosin contractile ring(GO:0005826) myosin II filament(GO:0097513) |
0.0 | 0.1 | GO:0097450 | astrocyte end-foot(GO:0097450) |
0.0 | 0.5 | GO:0045180 | basal cortex(GO:0045180) |
0.0 | 0.1 | GO:0016533 | cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533) |
0.0 | 0.2 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
0.0 | 0.3 | GO:0042382 | paraspeckles(GO:0042382) |
0.0 | 1.0 | GO:0030132 | clathrin coat of coated pit(GO:0030132) |
0.0 | 0.5 | GO:0034709 | methylosome(GO:0034709) |
0.0 | 0.1 | GO:0031673 | H zone(GO:0031673) |
0.0 | 0.2 | GO:0097129 | cyclin D2-CDK4 complex(GO:0097129) |
0.0 | 0.1 | GO:0030849 | autosome(GO:0030849) |
0.0 | 0.3 | GO:0043219 | myelin sheath adaxonal region(GO:0035749) lateral loop(GO:0043219) |
0.0 | 0.1 | GO:0072536 | interleukin-23 receptor complex(GO:0072536) |
0.0 | 0.1 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
0.0 | 0.2 | GO:0030485 | smooth muscle contractile fiber(GO:0030485) |
0.0 | 0.3 | GO:0008541 | proteasome regulatory particle, lid subcomplex(GO:0008541) |
0.0 | 0.3 | GO:0042587 | glycogen granule(GO:0042587) |
0.0 | 0.2 | GO:0005610 | laminin-5 complex(GO:0005610) |
0.0 | 0.0 | GO:0000806 | Y chromosome(GO:0000806) |
0.0 | 0.2 | GO:0000796 | condensin complex(GO:0000796) |
0.0 | 0.2 | GO:0043541 | UDP-N-acetylglucosamine transferase complex(GO:0043541) |
0.0 | 0.8 | GO:0097228 | sperm principal piece(GO:0097228) |
0.0 | 0.3 | GO:0005583 | fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643) |
0.0 | 0.4 | GO:0008290 | F-actin capping protein complex(GO:0008290) |
0.0 | 0.1 | GO:0035686 | sperm fibrous sheath(GO:0035686) |
0.0 | 0.2 | GO:0030314 | junctional membrane complex(GO:0030314) |
0.0 | 0.1 | GO:0000110 | nucleotide-excision repair factor 1 complex(GO:0000110) |
0.0 | 0.1 | GO:0071065 | alpha9-beta1 integrin-vascular cell adhesion molecule-1 complex(GO:0071065) |
0.0 | 0.2 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
0.0 | 0.1 | GO:1990745 | EARP complex(GO:1990745) |
0.0 | 0.6 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 0.1 | GO:0033165 | interphotoreceptor matrix(GO:0033165) |
0.0 | 0.3 | GO:0042622 | photoreceptor outer segment membrane(GO:0042622) |
0.0 | 0.1 | GO:0031084 | BLOC-2 complex(GO:0031084) |
0.0 | 0.2 | GO:0042612 | MHC class I protein complex(GO:0042612) |
0.0 | 0.1 | GO:0031415 | NatA complex(GO:0031415) |
0.0 | 0.1 | GO:0000221 | vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221) |
0.0 | 0.0 | GO:0097679 | other organism cytoplasm(GO:0097679) |
0.0 | 0.0 | GO:1990876 | cytoplasmic side of nuclear pore(GO:1990876) |
0.0 | 0.3 | GO:0016281 | eukaryotic translation initiation factor 4F complex(GO:0016281) |
0.0 | 0.1 | GO:0043196 | varicosity(GO:0043196) |
0.0 | 0.2 | GO:0044431 | Golgi apparatus part(GO:0044431) |
0.0 | 0.2 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
0.0 | 0.1 | GO:0005602 | complement component C1 complex(GO:0005602) |
0.0 | 0.1 | GO:0005726 | perichromatin fibrils(GO:0005726) |
0.0 | 0.1 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
0.0 | 0.1 | GO:0036449 | microtubule minus-end(GO:0036449) |
0.0 | 0.2 | GO:0045120 | pronucleus(GO:0045120) |
0.0 | 0.1 | GO:0044305 | calyx of Held(GO:0044305) |
0.0 | 0.1 | GO:0031931 | TORC1 complex(GO:0031931) |
0.0 | 0.2 | GO:0043020 | NADPH oxidase complex(GO:0043020) |
0.0 | 0.1 | GO:0009328 | phenylalanine-tRNA ligase complex(GO:0009328) |
0.0 | 0.1 | GO:0071439 | clathrin complex(GO:0071439) |
0.0 | 0.1 | GO:0016272 | prefoldin complex(GO:0016272) |
0.0 | 0.1 | GO:0070765 | gamma-secretase complex(GO:0070765) |
0.0 | 0.2 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
0.0 | 0.2 | GO:0001518 | voltage-gated sodium channel complex(GO:0001518) |
0.0 | 0.2 | GO:0099634 | postsynaptic specialization membrane(GO:0099634) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 1.2 | GO:0016404 | 15-hydroxyprostaglandin dehydrogenase (NAD+) activity(GO:0016404) |
0.3 | 1.3 | GO:0050436 | microfibril binding(GO:0050436) |
0.2 | 0.7 | GO:0036487 | nitric-oxide synthase inhibitor activity(GO:0036487) |
0.2 | 0.7 | GO:0005150 | interleukin-1, Type I receptor binding(GO:0005150) |
0.2 | 0.7 | GO:0016165 | linoleate 13S-lipoxygenase activity(GO:0016165) |
0.2 | 0.6 | GO:0016899 | oxidoreductase activity, acting on the CH-OH group of donors, oxygen as acceptor(GO:0016899) |
0.1 | 0.4 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
0.1 | 0.4 | GO:0033878 | hormone-sensitive lipase activity(GO:0033878) |
0.1 | 0.3 | GO:0004711 | ribosomal protein S6 kinase activity(GO:0004711) |
0.1 | 0.5 | GO:0032145 | 4-aminobutyrate transaminase activity(GO:0003867) succinate-semialdehyde dehydrogenase binding(GO:0032145) (S)-3-amino-2-methylpropionate transaminase activity(GO:0047298) |
0.1 | 0.6 | GO:0004668 | protein-arginine deiminase activity(GO:0004668) |
0.1 | 0.5 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
0.1 | 0.9 | GO:0005176 | ErbB-2 class receptor binding(GO:0005176) |
0.1 | 0.3 | GO:0070984 | SET domain binding(GO:0070984) |
0.1 | 0.3 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
0.1 | 0.2 | GO:0019981 | interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981) |
0.1 | 0.4 | GO:0004720 | protein-lysine 6-oxidase activity(GO:0004720) |
0.1 | 0.2 | GO:0031013 | troponin I binding(GO:0031013) |
0.1 | 1.2 | GO:0008179 | adenylate cyclase binding(GO:0008179) |
0.1 | 0.4 | GO:0004105 | choline-phosphate cytidylyltransferase activity(GO:0004105) |
0.1 | 1.5 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.1 | 2.2 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
0.1 | 0.5 | GO:0045499 | chemorepellent activity(GO:0045499) |
0.1 | 0.8 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
0.1 | 0.2 | GO:0051996 | farnesyl-diphosphate farnesyltransferase activity(GO:0004310) squalene synthase activity(GO:0051996) |
0.1 | 0.2 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.1 | 0.3 | GO:0031962 | mineralocorticoid receptor binding(GO:0031962) |
0.1 | 0.4 | GO:0004465 | lipoprotein lipase activity(GO:0004465) |
0.1 | 0.4 | GO:0061575 | cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575) |
0.1 | 0.7 | GO:0048019 | receptor antagonist activity(GO:0048019) |
0.1 | 0.4 | GO:0070087 | chromo shadow domain binding(GO:0070087) |
0.1 | 0.2 | GO:0004706 | JUN kinase kinase kinase activity(GO:0004706) |
0.1 | 0.2 | GO:0017095 | heparan sulfate 6-O-sulfotransferase activity(GO:0017095) |
0.1 | 0.2 | GO:0050501 | hyaluronan synthase activity(GO:0050501) |
0.1 | 0.3 | GO:0000298 | endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432) inositol diphosphate tetrakisphosphate diphosphatase activity(GO:0052840) inositol bisdiphosphate tetrakisphosphate diphosphatase activity(GO:0052841) inositol diphosphate pentakisphosphate diphosphatase activity(GO:0052842) inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity(GO:0052843) inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity(GO:0052844) inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity(GO:0052845) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity(GO:0052846) inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052847) inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity(GO:0052848) |
0.1 | 0.3 | GO:0030348 | syntaxin-3 binding(GO:0030348) |
0.0 | 0.5 | GO:0008430 | selenium binding(GO:0008430) |
0.0 | 0.1 | GO:0050698 | proteoglycan sulfotransferase activity(GO:0050698) |
0.0 | 0.1 | GO:0050659 | N-acetylgalactosamine 4-sulfate 6-O-sulfotransferase activity(GO:0050659) |
0.0 | 0.3 | GO:0010859 | calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859) |
0.0 | 0.6 | GO:0032050 | clathrin heavy chain binding(GO:0032050) |
0.0 | 0.4 | GO:0005143 | interleukin-12 receptor binding(GO:0005143) |
0.0 | 0.3 | GO:0016314 | phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314) |
0.0 | 0.2 | GO:0031749 | D2 dopamine receptor binding(GO:0031749) |
0.0 | 0.1 | GO:0004345 | glucose-6-phosphate dehydrogenase activity(GO:0004345) |
0.0 | 0.2 | GO:0050509 | N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity(GO:0050509) |
0.0 | 0.1 | GO:0016534 | cyclin-dependent protein kinase 5 activator activity(GO:0016534) |
0.0 | 0.1 | GO:0004531 | deoxyribonuclease II activity(GO:0004531) |
0.0 | 0.1 | GO:0004464 | leukotriene-C4 synthase activity(GO:0004464) |
0.0 | 0.7 | GO:0017070 | U6 snRNA binding(GO:0017070) |
0.0 | 0.2 | GO:0004830 | tryptophan-tRNA ligase activity(GO:0004830) |
0.0 | 0.8 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
0.0 | 0.1 | GO:0008798 | beta-aspartyl-peptidase activity(GO:0008798) |
0.0 | 0.1 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
0.0 | 0.1 | GO:0003985 | acetyl-CoA C-acetyltransferase activity(GO:0003985) |
0.0 | 0.4 | GO:0010385 | double-stranded methylated DNA binding(GO:0010385) |
0.0 | 0.6 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
0.0 | 0.1 | GO:0004914 | interleukin-5 receptor activity(GO:0004914) |
0.0 | 0.4 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
0.0 | 1.5 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
0.0 | 0.8 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.0 | 0.1 | GO:0005166 | neurotrophin p75 receptor binding(GO:0005166) |
0.0 | 0.0 | GO:0010484 | H3 histone acetyltransferase activity(GO:0010484) |
0.0 | 0.6 | GO:0017017 | MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017) |
0.0 | 0.1 | GO:0031731 | CCR6 chemokine receptor binding(GO:0031731) |
0.0 | 0.2 | GO:0004348 | glucosylceramidase activity(GO:0004348) |
0.0 | 0.2 | GO:0022850 | serotonin-gated cation channel activity(GO:0022850) |
0.0 | 0.1 | GO:0010698 | acetyltransferase activator activity(GO:0010698) |
0.0 | 0.2 | GO:0044378 | non-sequence-specific DNA binding, bending(GO:0044378) |
0.0 | 0.1 | GO:1990190 | peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
0.0 | 0.1 | GO:0004618 | phosphoglycerate kinase activity(GO:0004618) |
0.0 | 0.1 | GO:0004743 | pyruvate kinase activity(GO:0004743) |
0.0 | 0.2 | GO:0004111 | creatine kinase activity(GO:0004111) |
0.0 | 0.1 | GO:0004489 | methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489) |
0.0 | 0.5 | GO:0032036 | myosin heavy chain binding(GO:0032036) |
0.0 | 0.5 | GO:0016273 | arginine N-methyltransferase activity(GO:0016273) protein-arginine N-methyltransferase activity(GO:0016274) |
0.0 | 0.1 | GO:0034189 | very-low-density lipoprotein particle binding(GO:0034189) |
0.0 | 0.1 | GO:0005294 | neutral L-amino acid secondary active transmembrane transporter activity(GO:0005294) |
0.0 | 0.1 | GO:0010465 | nerve growth factor receptor activity(GO:0010465) |
0.0 | 0.1 | GO:0051431 | corticotropin-releasing hormone receptor 2 binding(GO:0051431) |
0.0 | 0.1 | GO:0035539 | 8-oxo-7,8-dihydroguanosine triphosphate pyrophosphatase activity(GO:0008413) 8-oxo-7,8-dihydrodeoxyguanosine triphosphate pyrophosphatase activity(GO:0035539) |
0.0 | 0.2 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
0.0 | 0.5 | GO:0005225 | volume-sensitive anion channel activity(GO:0005225) |
0.0 | 0.2 | GO:0035473 | lipase binding(GO:0035473) |
0.0 | 0.1 | GO:0015173 | aromatic amino acid transmembrane transporter activity(GO:0015173) |
0.0 | 0.3 | GO:0004849 | uridine kinase activity(GO:0004849) |
0.0 | 0.2 | GO:0001591 | dopamine neurotransmitter receptor activity, coupled via Gi/Go(GO:0001591) |
0.0 | 0.1 | GO:0086006 | voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006) |
0.0 | 0.1 | GO:0003726 | double-stranded RNA adenosine deaminase activity(GO:0003726) |
0.0 | 0.1 | GO:0016934 | extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934) |
0.0 | 0.1 | GO:0047391 | alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391) |
0.0 | 0.1 | GO:0004102 | choline O-acetyltransferase activity(GO:0004102) |
0.0 | 0.2 | GO:0015252 | hydrogen ion channel activity(GO:0015252) |
0.0 | 0.2 | GO:0046976 | histone methyltransferase activity (H3-K27 specific)(GO:0046976) |
0.0 | 0.1 | GO:0033677 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) DNA/RNA helicase activity(GO:0033677) |
0.0 | 0.5 | GO:0030898 | actin-dependent ATPase activity(GO:0030898) |
0.0 | 0.4 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
0.0 | 0.1 | GO:0099609 | microtubule lateral binding(GO:0099609) |
0.0 | 0.1 | GO:0070051 | fibrinogen binding(GO:0070051) |
0.0 | 0.1 | GO:0000253 | 3-keto sterol reductase activity(GO:0000253) |
0.0 | 0.1 | GO:0046974 | histone methyltransferase activity (H3-K9 specific)(GO:0046974) |
0.0 | 0.4 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
0.0 | 0.1 | GO:0045518 | interleukin-22 receptor binding(GO:0045518) |
0.0 | 0.1 | GO:0019961 | interferon binding(GO:0019961) |
0.0 | 0.2 | GO:0070097 | delta-catenin binding(GO:0070097) |
0.0 | 0.2 | GO:0050544 | arachidonic acid binding(GO:0050544) |
0.0 | 0.1 | GO:0033743 | peptide-methionine (R)-S-oxide reductase activity(GO:0033743) |
0.0 | 0.1 | GO:0001181 | transcription factor activity, core RNA polymerase I binding(GO:0001181) |
0.0 | 0.2 | GO:0001730 | 2'-5'-oligoadenylate synthetase activity(GO:0001730) |
0.0 | 0.1 | GO:0004663 | Rab geranylgeranyltransferase activity(GO:0004663) |
0.0 | 0.1 | GO:1990599 | 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599) |
0.0 | 0.1 | GO:1990254 | keratin filament binding(GO:1990254) |
0.0 | 0.1 | GO:0045125 | bioactive lipid receptor activity(GO:0045125) |
0.0 | 0.1 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
0.0 | 0.1 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
0.0 | 1.2 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
0.0 | 0.1 | GO:0099580 | ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580) |
0.0 | 0.2 | GO:0030274 | LIM domain binding(GO:0030274) |
0.0 | 0.2 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
0.0 | 0.1 | GO:0047192 | 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192) |
0.0 | 0.0 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.0 | 0.4 | GO:0033130 | acetylcholine receptor binding(GO:0033130) |
0.0 | 0.1 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.0 | 0.1 | GO:0004126 | cytidine deaminase activity(GO:0004126) |
0.0 | 0.2 | GO:0043855 | intracellular cyclic nucleotide activated cation channel activity(GO:0005221) cyclic nucleotide-gated ion channel activity(GO:0043855) |
0.0 | 0.1 | GO:0031802 | type 5 metabotropic glutamate receptor binding(GO:0031802) |
0.0 | 0.5 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.0 | 0.5 | GO:0005523 | tropomyosin binding(GO:0005523) |
0.0 | 0.4 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
0.0 | 0.1 | GO:0004719 | protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719) |
0.0 | 0.4 | GO:0003746 | translation elongation factor activity(GO:0003746) |
0.0 | 0.2 | GO:0036402 | proteasome-activating ATPase activity(GO:0036402) |
0.0 | 0.1 | GO:0043426 | MRF binding(GO:0043426) |
0.0 | 0.2 | GO:0016175 | superoxide-generating NADPH oxidase activity(GO:0016175) |
0.0 | 0.1 | GO:0004952 | dopamine neurotransmitter receptor activity(GO:0004952) |
0.0 | 0.1 | GO:0004117 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) |
0.0 | 0.2 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
0.0 | 0.1 | GO:0003875 | ADP-ribosylarginine hydrolase activity(GO:0003875) |
0.0 | 0.1 | GO:0034711 | inhibin binding(GO:0034711) |
0.0 | 0.3 | GO:0019992 | diacylglycerol binding(GO:0019992) |
0.0 | 0.8 | GO:0004693 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) |
0.0 | 0.1 | GO:0004340 | glucokinase activity(GO:0004340) hexokinase activity(GO:0004396) fructokinase activity(GO:0008865) mannokinase activity(GO:0019158) |
0.0 | 0.1 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
0.0 | 0.1 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) |
0.0 | 0.1 | GO:0051525 | NFAT protein binding(GO:0051525) |
0.0 | 0.2 | GO:0017022 | myosin binding(GO:0017022) |
0.0 | 0.2 | GO:0035615 | clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748) |
0.0 | 0.1 | GO:0047288 | monosialoganglioside sialyltransferase activity(GO:0047288) |
0.0 | 0.1 | GO:0004000 | adenosine deaminase activity(GO:0004000) |
0.0 | 0.4 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
0.0 | 0.0 | GO:0000773 | phosphatidyl-N-methylethanolamine N-methyltransferase activity(GO:0000773) phosphatidylethanolamine N-methyltransferase activity(GO:0004608) phosphatidyl-N-dimethylethanolamine N-methyltransferase activity(GO:0080101) |
0.0 | 0.1 | GO:0005536 | glucose binding(GO:0005536) |
0.0 | 0.2 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
0.0 | 0.1 | GO:0061649 | ubiquitinated histone binding(GO:0061649) |
0.0 | 0.2 | GO:0042834 | peptidoglycan binding(GO:0042834) |
0.0 | 0.1 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.0 | 0.0 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
0.0 | 0.1 | GO:0030614 | oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) |
0.0 | 0.2 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
0.0 | 3.4 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
0.0 | 0.2 | GO:0047372 | acylglycerol lipase activity(GO:0047372) |
0.0 | 0.1 | GO:0047045 | testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045) |
0.0 | 0.4 | GO:0016628 | oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor(GO:0016628) |
0.0 | 0.3 | GO:0008327 | methyl-CpG binding(GO:0008327) |
0.0 | 0.3 | GO:0030676 | Rac guanyl-nucleotide exchange factor activity(GO:0030676) |
Gene overrepresentation in C2:CP category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 2.8 | SA_MMP_CYTOKINE_CONNECTION | Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix. |
0.0 | 0.8 | PID_VEGF_VEGFR_PATHWAY | VEGF and VEGFR signaling network |
0.0 | 0.1 | PID_ERBB4_PATHWAY | ErbB4 signaling events |
0.0 | 1.3 | PID_ERBB_NETWORK_PATHWAY | ErbB receptor signaling network |
0.0 | 0.1 | PID_TRAIL_PATHWAY | TRAIL signaling pathway |
0.0 | 0.8 | PID_LPA4_PATHWAY | LPA4-mediated signaling events |
0.0 | 0.7 | PID_ARF_3PATHWAY | Arf1 pathway |
0.0 | 0.3 | ST_IL_13_PATHWAY | Interleukin 13 (IL-13) Pathway |
0.0 | 1.6 | PID_FOXM1_PATHWAY | FOXM1 transcription factor network |
0.0 | 0.7 | PID_WNT_SIGNALING_PATHWAY | Wnt signaling network |
0.0 | 0.4 | PID_ARF6_DOWNSTREAM_PATHWAY | Arf6 downstream pathway |
0.0 | 0.7 | PID_TOLL_ENDOGENOUS_PATHWAY | Endogenous TLR signaling |
0.0 | 0.4 | PID_RHODOPSIN_PATHWAY | Visual signal transduction: Rods |
0.0 | 0.6 | PID_INTEGRIN5_PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
0.0 | 0.6 | PID_IL1_PATHWAY | IL1-mediated signaling events |
0.0 | 0.6 | PID_EPHRINB_REV_PATHWAY | Ephrin B reverse signaling |
0.0 | 0.6 | ST_INTERLEUKIN_4_PATHWAY | Interleukin 4 (IL-4) Pathway |
0.0 | 1.5 | PID_HDAC_CLASSI_PATHWAY | Signaling events mediated by HDAC Class I |
0.0 | 0.4 | PID_SMAD2_3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
0.0 | 0.3 | PID_CONE_PATHWAY | Visual signal transduction: Cones |
0.0 | 1.4 | PID_CDC42_PATHWAY | CDC42 signaling events |
0.0 | 0.7 | PID_LKB1_PATHWAY | LKB1 signaling events |
0.0 | 0.1 | PID_IL5_PATHWAY | IL5-mediated signaling events |
0.0 | 0.4 | PID_INSULIN_GLUCOSE_PATHWAY | Insulin-mediated glucose transport |
0.0 | 0.3 | PID_THROMBIN_PAR1_PATHWAY | PAR1-mediated thrombin signaling events |
0.0 | 0.4 | ST_JNK_MAPK_PATHWAY | JNK MAPK Pathway |
0.0 | 0.3 | PID_INTEGRIN_A9B1_PATHWAY | Alpha9 beta1 integrin signaling events |
0.0 | 0.3 | PID_CIRCADIAN_PATHWAY | Circadian rhythm pathway |
0.0 | 0.3 | SIG_CD40PATHWAYMAP | Genes related to CD40 signaling |
0.0 | 0.4 | PID_SYNDECAN_2_PATHWAY | Syndecan-2-mediated signaling events |
0.0 | 0.0 | PID_S1P_S1P2_PATHWAY | S1P2 pathway |
Gene overrepresentation in C2:CP:REACTOME category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 1.8 | REACTOME_HYALURONAN_UPTAKE_AND_DEGRADATION | Genes involved in Hyaluronan uptake and degradation |
0.1 | 1.6 | REACTOME_SYNTHESIS_SECRETION_AND_INACTIVATION_OF_GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
0.1 | 1.0 | REACTOME_ADENYLATE_CYCLASE_ACTIVATING_PATHWAY | Genes involved in Adenylate cyclase activating pathway |
0.0 | 0.9 | REACTOME_GAP_JUNCTION_DEGRADATION | Genes involved in Gap junction degradation |
0.0 | 0.9 | REACTOME_DOPAMINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Dopamine Neurotransmitter Release Cycle |
0.0 | 1.3 | REACTOME_CYCLIN_A_B1_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION | Genes involved in Cyclin A/B1 associated events during G2/M transition |
0.0 | 0.8 | REACTOME_NEF_MEDIATED_DOWNREGULATION_OF_MHC_CLASS_I_COMPLEX_CELL_SURFACE_EXPRESSION | Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression |
0.0 | 1.2 | REACTOME_DOWNREGULATION_OF_ERBB2_ERBB3_SIGNALING | Genes involved in Downregulation of ERBB2:ERBB3 signaling |
0.0 | 0.8 | REACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION | Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion |
0.0 | 2.0 | REACTOME_IL1_SIGNALING | Genes involved in Interleukin-1 signaling |
0.0 | 0.6 | REACTOME_CS_DS_DEGRADATION | Genes involved in CS/DS degradation |
0.0 | 0.5 | REACTOME_IL_6_SIGNALING | Genes involved in Interleukin-6 signaling |
0.0 | 0.4 | REACTOME_KERATAN_SULFATE_DEGRADATION | Genes involved in Keratan sulfate degradation |
0.0 | 0.2 | REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY | Genes involved in Endosomal/Vacuolar pathway |
0.0 | 0.7 | REACTOME_PTM_GAMMA_CARBOXYLATION_HYPUSINE_FORMATION_AND_ARYLSULFATASE_ACTIVATION | Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation |
0.0 | 0.2 | REACTOME_ERKS_ARE_INACTIVATED | Genes involved in ERKs are inactivated |
0.0 | 0.3 | REACTOME_COMMON_PATHWAY | Genes involved in Common Pathway |
0.0 | 0.9 | REACTOME_G1_PHASE | Genes involved in G1 Phase |
0.0 | 0.5 | REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PLC_BETA | Genes involved in G beta:gamma signalling through PLC beta |
0.0 | 0.4 | REACTOME_PROTEOLYTIC_CLEAVAGE_OF_SNARE_COMPLEX_PROTEINS | Genes involved in Proteolytic cleavage of SNARE complex proteins |
0.0 | 0.6 | REACTOME_SYNTHESIS_AND_INTERCONVERSION_OF_NUCLEOTIDE_DI_AND_TRIPHOSPHATES | Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates |
0.0 | 0.3 | REACTOME_ACTIVATION_OF_THE_AP1_FAMILY_OF_TRANSCRIPTION_FACTORS | Genes involved in Activation of the AP-1 family of transcription factors |
0.0 | 0.5 | REACTOME_CHOLESTEROL_BIOSYNTHESIS | Genes involved in Cholesterol biosynthesis |
0.0 | 0.3 | REACTOME_REPAIR_SYNTHESIS_FOR_GAP_FILLING_BY_DNA_POL_IN_TC_NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
0.0 | 0.5 | REACTOME_SIGNALING_BY_NODAL | Genes involved in Signaling by NODAL |
0.0 | 0.5 | REACTOME_HORMONE_SENSITIVE_LIPASE_HSL_MEDIATED_TRIACYLGLYCEROL_HYDROLYSIS | Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis |
0.0 | 0.3 | REACTOME_GABA_SYNTHESIS_RELEASE_REUPTAKE_AND_DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
0.0 | 0.1 | REACTOME_ACETYLCHOLINE_NEUROTRANSMITTER_RELEASE_CYCLE | Genes involved in Acetylcholine Neurotransmitter Release Cycle |
0.0 | 0.2 | REACTOME_HORMONE_LIGAND_BINDING_RECEPTORS | Genes involved in Hormone ligand-binding receptors |
0.0 | 0.4 | REACTOME_BETA_DEFENSINS | Genes involved in Beta defensins |
0.0 | 0.6 | REACTOME_REGULATION_OF_INSULIN_SECRETION_BY_GLUCAGON_LIKE_PEPTIDE1 | Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1 |
0.0 | 0.3 | REACTOME_REGULATION_OF_GENE_EXPRESSION_IN_BETA_CELLS | Genes involved in Regulation of gene expression in beta cells |
0.0 | 0.2 | REACTOME_PURINE_RIBONUCLEOSIDE_MONOPHOSPHATE_BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
0.0 | 0.2 | REACTOME_G0_AND_EARLY_G1 | Genes involved in G0 and Early G1 |
0.0 | 0.3 | REACTOME_SYNTHESIS_OF_PC | Genes involved in Synthesis of PC |
0.0 | 0.1 | REACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS | Genes involved in Elevation of cytosolic Ca2+ levels |
0.0 | 0.5 | REACTOME_PACKAGING_OF_TELOMERE_ENDS | Genes involved in Packaging Of Telomere Ends |